WO2024002118A1 - Ultrasonic probe apparatus for magnetic resonance-guided focus ultrasound - Google Patents

Ultrasonic probe apparatus for magnetic resonance-guided focus ultrasound Download PDF

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Publication number
WO2024002118A1
WO2024002118A1 PCT/CN2023/103003 CN2023103003W WO2024002118A1 WO 2024002118 A1 WO2024002118 A1 WO 2024002118A1 CN 2023103003 W CN2023103003 W CN 2023103003W WO 2024002118 A1 WO2024002118 A1 WO 2024002118A1
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probe
ultrasonic
units
focusing
connecting rod
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PCT/CN2023/103003
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French (fr)
Chinese (zh)
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张辉
田周
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上海沈德无创时代医疗科技有限公司
沈德(宁波)医疗器械科技有限公司
南通沈德医疗器械科技有限公司
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Publication of WO2024002118A1 publication Critical patent/WO2024002118A1/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32Surgical cutting instruments
    • A61B17/320068Surgical cutting instruments using mechanical vibrations, e.g. ultrasonic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/36Image-producing devices or illumination devices not otherwise provided for
    • A61B90/37Surgical systems with images on a monitor during operation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32Surgical cutting instruments
    • A61B17/320068Surgical cutting instruments using mechanical vibrations, e.g. ultrasonic
    • A61B2017/320069Surgical cutting instruments using mechanical vibrations, e.g. ultrasonic for ablating tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/36Image-producing devices or illumination devices not otherwise provided for
    • A61B90/37Surgical systems with images on a monitor during operation
    • A61B2090/374NMR or MRI

Definitions

  • the present invention relates to the field of magnetic wave knife, and in particular to an ultrasonic probe device used for magnetic wave knife.
  • Magnetic wave knife is also called ultrasonic focusing knife. It can cooperate with magnetic resonance real-time imaging and use ultrasonic waves as energy to disperse and transmit from outside the body to the inside of the body. Focusing occurs during the transmission process. Many ultrasonic waves are focused on one point. This point Through the conversion of sound waves and heat energy, a high-energy treatment point is formed to kill tumor cells.
  • magnetic wave knife has shown good results in the clinical treatment of uterine fibroids, brain tumors, prostate tumors, etc. Magnetic wave knife generally works under the guidance of imaging equipment such as magnetic resonance. Through phased array control, it is necessary to obtain real-time images around the diseased tissue from the imaging equipment. It is convenient for doctors to plan treatment before surgery and to facilitate preliminary evaluation of treatment effects after surgery. When the doctor determines the ablation area and prepares for ablation surgery, the focal length of the ultrasound probe plays a key role in selectively ablating the diseased tissue and determines the effective depth of the treatment lesion.
  • the focal distance of the ultrasonic probe of the magnetic wave knife is fixed. For different situations, it is necessary to replace the ultrasonic probe with different focal distance. Even if it is replaced multiple times in one operation, and multiple magnetic resonance guidance is performed, it will cause serious problems. Affect the efficiency of surgery, thereby increasing the safety risks of the treatment process.
  • the purpose of the present invention is to provide an ultrasonic probe device for magnetic wave knife in order to overcome the above-mentioned defects in the prior art.
  • An ultrasonic probe device for magnetic wave knife characterized in that it includes a probe holder, a probe connecting rod and a plurality of probe units.
  • the probe connecting rod is connected to one axial end of the probe holder, and each probe unit is provided with The focusing surface is used to form an ultrasonic focusing point.
  • the depth of the ultrasonic focusing point of at least one probe unit is different from that of other probe units.
  • the plurality of probe units are installed on the probe bracket so that their focusing surfaces are distributed on the circumferential side of the probe bracket.
  • curvature radii of the focusing surfaces of the plurality of probe units are different from each other.
  • mounting grooves are distributed around the circumference of the probe bracket, and the probe unit is embedded in the mounting grooves for fixation.
  • the number of the probe units is at least two.
  • probe bracket and the probe connecting rod are connected through threads.
  • the present invention has the following beneficial effects:
  • the present invention integrates multiple probe units so that one device has multiple ultrasound focus depths, thereby achieving multiple ablation of lesions in different areas under one magnetic resonance guidance, reducing the patient's treatment time and greatly improving the patient's treatment time. Usage efficiency.
  • the curvature radii of the focusing surfaces of multiple probe units are different from each other, which improves its application range.
  • the installation structure of the probe unit and probe bracket is simple, which is convenient for production and manufacturing; the probe unit and probe bracket can also adopt a detachable structure for easy replacement.
  • the probe bracket and probe connecting rod are threaded, which is easy to disassemble and replace, and has good practical value.
  • Figure 1 is a schematic structural diagram of the present invention.
  • Figure 2 is a schematic diagram of the explosion structure of the present invention.
  • Probe bracket 11. Installation slot, 2. Probe connecting rod, 3. Probe unit, 31. Focusing surface.
  • this embodiment provides an ultrasonic probe device for magnetic wave knife, including a probe holder 1 , a probe connecting rod 2 and a plurality of probe units 3 .
  • the main body of the probe holder 1 is cylindrical, and a plurality of mounting grooves 11 are distributed on the circumferential side walls of the holder.
  • the number of mounting slots 11 corresponds to the probe unit 3 and is at least two. In this embodiment, it is preferably set to three.
  • a focusing surface 31 is provided on the outer surface of each probe unit 3 for forming an ultrasonic focusing focus.
  • the focal plane 31 surrounds the probe holder 1 .
  • At least one probe unit 3 and other probe units 3 have different ultrasonic focus depths.
  • One end of the probe connecting rod 2 is threadedly connected and fixed to the probe bracket 1.
  • the external probe control mechanism can drive the probe bracket 1 to rotate and move through the probe connecting rod 2.
  • the overall manufacturing material of the probe device is non-magnetic and fully compatible with MRI equipment.
  • the method of fixing the probe unit 3 in the installation slot 11 is not limited in detail, and may be in the form of a snap, adhesive fixation or interference fit fixation.
  • the probe connecting rod 2 is a pipe structure, the ultrasonic source is located inside the probe holder 1, and its wires connected to external equipment are led out from the pipe.
  • the working principle of this embodiment is: the present invention uses probe units 3 with three curvature radii integrated into the probe holder 1.
  • the probe holder 1 follows the probe connecting rod 2 and rotates 120°, it will replace a probe unit 3 with a different curvature radius. Thereby changing the ultrasound focus.
  • This embodiment can make up for the shortcomings in the spatial movement range of the phase-controlled focusing focus of the ultrasound system during the treatment process, and is of great significance for achieving large-scale tumor ablation and reducing ablation errors.
  • this embodiment uses three curvature probes integrated together, which increases the focusing depth of the ultrasonic focus and facilitates the treatment of different patients and lesions of different depths; the integrated application of the three-curved probes improves the treatment efficiency and can achieve One magnetic resonance guidance can ablate lesions in different areas multiple times, greatly reducing the patient's treatment time and pain.

Abstract

Provided is an ultrasonic probe apparatus for magnetic resonance-guided focus ultrasound, comprising a probe support (1), a probe connecting rod (2), and a plurality of probe units (3). The probe connecting rod (2) is connected with one axial end of the probe support (1). Each probe unit (3) is provided with a focusing surface (31) configured for forming an ultrasonic focal point. At least one probe unit (3) has an ultrasonic focal depth different from those of the other probe units (3). The plurality of probe units (3) are mounted on the probe support (1), such that the focusing surfaces (31) thereof are distributed on the circumferential side surface of the probe support (1). The ultrasonic probe apparatus integrates the plurality of probe units (3) to allow multiple ultrasonic focal depths on a single apparatus, thereby achieving the ablation of multiple lesions in different areas with the guidance of a single magnetic resonance imaging, reducing the treatment period of a patient, and greatly improving the efficiency.

Description

一种用于磁波刀的超声探头装置An ultrasonic probe device for magnetic wave knife 技术领域Technical field
本发明涉及一种磁波刀领域,尤其是涉及一种用于磁波刀的超声探头装置。The present invention relates to the field of magnetic wave knife, and in particular to an ultrasonic probe device used for magnetic wave knife.
背景技术Background technique
磁波刀也称为超声聚焦刀,其可以配合磁共振实时成像,利用超声波作能源,从体外分散发射到身体里边去,在发射透射过程中间发生聚焦,很多超声波聚焦在一个点上,这一个点上通过声波和热能转化,形成一个高能治疗点,用于杀死肿瘤细胞。近年来,磁波刀在子宫肌瘤、脑肿瘤、前列腺肿瘤等临床治疗中表现出了良好的效果。磁波刀一般是在磁共振等成像设备引导下工作,通过相控阵控制,需要从成像设备中实时获取病变组织周围的图像,术前便于医生进行治疗规划,术后便于初步评估治疗效果。当医生确定了消融区域准备进行消融手术时,超声探头的焦点距离,对于有选择地消融病变组织起着关键的作用,决定了治疗病灶的有效深度。Magnetic wave knife is also called ultrasonic focusing knife. It can cooperate with magnetic resonance real-time imaging and use ultrasonic waves as energy to disperse and transmit from outside the body to the inside of the body. Focusing occurs during the transmission process. Many ultrasonic waves are focused on one point. This point Through the conversion of sound waves and heat energy, a high-energy treatment point is formed to kill tumor cells. In recent years, magnetic wave knife has shown good results in the clinical treatment of uterine fibroids, brain tumors, prostate tumors, etc. Magnetic wave knife generally works under the guidance of imaging equipment such as magnetic resonance. Through phased array control, it is necessary to obtain real-time images around the diseased tissue from the imaging equipment. It is convenient for doctors to plan treatment before surgery and to facilitate preliminary evaluation of treatment effects after surgery. When the doctor determines the ablation area and prepares for ablation surgery, the focal length of the ultrasound probe plays a key role in selectively ablating the diseased tissue and determines the effective depth of the treatment lesion.
现有技术中,磁波刀超声探头的焦点距离都是固定的,对于不同的情况需要替换采用不同焦点距离的超声探头,甚至在一次手术中替换多次,并多次进行磁共振引导,会严重影响手术效率,从而加大治疗过程的安全风险。In the existing technology, the focal distance of the ultrasonic probe of the magnetic wave knife is fixed. For different situations, it is necessary to replace the ultrasonic probe with different focal distance. Even if it is replaced multiple times in one operation, and multiple magnetic resonance guidance is performed, it will cause serious problems. Affect the efficiency of surgery, thereby increasing the safety risks of the treatment process.
发明内容Contents of the invention
本发明的目的就是为了克服上述现有技术存在的缺陷而提供一种用于磁波刀的超声探头装置。The purpose of the present invention is to provide an ultrasonic probe device for magnetic wave knife in order to overcome the above-mentioned defects in the prior art.
本发明的目的可以通过以下技术方案来实现:The object of the present invention can be achieved through the following technical solutions:
一种用于磁波刀的超声探头装置,其特征在于,包括探头支架、探头连接杆和多个探头单元,所述探头连接杆连接所述探头支架的轴向一端,每个探头单元上设有聚焦面用于形成超声聚焦点,至少一个探头单元和其它探头单元的超声聚焦点深度不同,所述多个探头单元安装在探头支架上,使其聚焦面分布在探头支架的周向侧面。 An ultrasonic probe device for magnetic wave knife, characterized in that it includes a probe holder, a probe connecting rod and a plurality of probe units. The probe connecting rod is connected to one axial end of the probe holder, and each probe unit is provided with The focusing surface is used to form an ultrasonic focusing point. The depth of the ultrasonic focusing point of at least one probe unit is different from that of other probe units. The plurality of probe units are installed on the probe bracket so that their focusing surfaces are distributed on the circumferential side of the probe bracket.
进一步地,多个探头单元的聚焦面的曲率半径互不相同。Further, the curvature radii of the focusing surfaces of the plurality of probe units are different from each other.
进一步地,所述探头支架的周向分布有安装槽,所述探头单元嵌入安装槽中进行固定。Further, mounting grooves are distributed around the circumference of the probe bracket, and the probe unit is embedded in the mounting grooves for fixation.
进一步地,所述探头单元的数量至少为两个。Further, the number of the probe units is at least two.
进一步地,所述探头支架和探头连接杆通过螺纹连接。Further, the probe bracket and the probe connecting rod are connected through threads.
与现有技术相比,本发明具有以下有益效果:Compared with the prior art, the present invention has the following beneficial effects:
1、本发明将多个探头单元集成在一起,使一个装置具有多个超声聚焦深度,从而实现一次磁共振引导下,多次消融不同区域的病灶,减少了患者的治疗时间,极大提高了使用效率。1. The present invention integrates multiple probe units so that one device has multiple ultrasound focus depths, thereby achieving multiple ablation of lesions in different areas under one magnetic resonance guidance, reducing the patient's treatment time and greatly improving the patient's treatment time. Usage efficiency.
2、多个探头单元的聚焦面的曲率半径均互不相同,提高其应用范围。2. The curvature radii of the focusing surfaces of multiple probe units are different from each other, which improves its application range.
3、探头单元和探头支架的安装结构简单,便于生产和制造;探头单元和探头支架也可采用可拆卸式结构,便于进行替换。3. The installation structure of the probe unit and probe bracket is simple, which is convenient for production and manufacturing; the probe unit and probe bracket can also adopt a detachable structure for easy replacement.
4、探头支架和探头连接杆采用螺纹连接,便于拆卸和替换,具有良好的实用价值。4. The probe bracket and probe connecting rod are threaded, which is easy to disassemble and replace, and has good practical value.
附图说明Description of drawings
图1为本发明的结构示意图。Figure 1 is a schematic structural diagram of the present invention.
图2为本发明的爆炸结构示意图。Figure 2 is a schematic diagram of the explosion structure of the present invention.
附图标记:1、探头支架,11、安装槽,2、探头连接杆,3、探头单元,31、聚焦面。Reference signs: 1. Probe bracket, 11. Installation slot, 2. Probe connecting rod, 3. Probe unit, 31. Focusing surface.
具体实施方式Detailed ways
下面结合附图和具体实施例对本发明进行详细说明。本实施例以本发明技术方案为前提进行实施,给出了详细的实施方式和具体的操作过程,但本发明的保护范围不限于下述的实施例。The present invention will be described in detail below with reference to the accompanying drawings and specific embodiments. This embodiment is implemented based on the technical solution of the present invention and provides detailed implementation modes and specific operating procedures. However, the protection scope of the present invention is not limited to the following embodiments.
如图1和图2所示,本实施例提供了一种用于磁波刀的超声探头装置,包括探头支架1、探头连接杆2和多个探头单元3。探头支架1的主体为圆柱形,在支架的周向侧壁上分布有多个安装槽11。安装槽11的数量和探头单元3对应,为至少两个,本实施例中优选设置为三个。探头单元3的数量为三个,分别嵌入三个安装槽11中。在每个探头单元3的外侧表面设有聚焦面31用于形成超声聚焦焦点,聚 焦面31环绕在探头支架1上。一般情况下,至少一个探头单元3和其它探头单元3的超声聚焦焦点深度不同,本实施例中优选采用三个聚焦面31的曲率半径均互不相同,使对应超声聚焦点的深度距离均各不相同,由此可以适用于三种不同的应用场景。探头连接杆2的一端和探头支架1螺纹连接固定,外置的探头控制机构可以通过探头连接杆2带动探头支架1旋转和移动。探头装置的整体制造材料无磁性,与MRI设备完全兼容。As shown in FIGS. 1 and 2 , this embodiment provides an ultrasonic probe device for magnetic wave knife, including a probe holder 1 , a probe connecting rod 2 and a plurality of probe units 3 . The main body of the probe holder 1 is cylindrical, and a plurality of mounting grooves 11 are distributed on the circumferential side walls of the holder. The number of mounting slots 11 corresponds to the probe unit 3 and is at least two. In this embodiment, it is preferably set to three. There are three probe units 3, which are respectively embedded in three installation slots 11. A focusing surface 31 is provided on the outer surface of each probe unit 3 for forming an ultrasonic focusing focus. The focal plane 31 surrounds the probe holder 1 . In general, at least one probe unit 3 and other probe units 3 have different ultrasonic focus depths. In this embodiment, it is preferred to use three focusing surfaces 31 with different curvature radii, so that the depth distances of the corresponding ultrasonic focus points are all different. are not the same, so they can be applied to three different application scenarios. One end of the probe connecting rod 2 is threadedly connected and fixed to the probe bracket 1. The external probe control mechanism can drive the probe bracket 1 to rotate and move through the probe connecting rod 2. The overall manufacturing material of the probe device is non-magnetic and fully compatible with MRI equipment.
探头单元3在安装槽11内的固定方式具体不限,可以是卡扣形式,也可以是黏贴固定或者过盈配合固定。探头连接杆2为管道结构,超声波源位于探头支架1内部,其连接外部设备的导线从管道中引出。The method of fixing the probe unit 3 in the installation slot 11 is not limited in detail, and may be in the form of a snap, adhesive fixation or interference fit fixation. The probe connecting rod 2 is a pipe structure, the ultrasonic source is located inside the probe holder 1, and its wires connected to external equipment are led out from the pipe.
本实施例的工作原理为:本发明采用三个曲率半径的探头单元3集成探头支架1上,当探头支架1跟随探头连接杆2每旋转120°后将更换一个曲率半径不同的探头单元3,从而改变超声聚焦焦点。本实施例能够弥补超声系统在治疗过程中相控聚焦的焦点在空间移动范围上的不足,对于实现大范围的肿瘤消融,减少消融误差具有巨大的意义。The working principle of this embodiment is: the present invention uses probe units 3 with three curvature radii integrated into the probe holder 1. When the probe holder 1 follows the probe connecting rod 2 and rotates 120°, it will replace a probe unit 3 with a different curvature radius. Thereby changing the ultrasound focus. This embodiment can make up for the shortcomings in the spatial movement range of the phase-controlled focusing focus of the ultrasound system during the treatment process, and is of great significance for achieving large-scale tumor ablation and reducing ablation errors.
综上所述,本实施例采用三个曲率的探头集成到一起,增加了超声焦点的聚焦深度,方便治疗不同病人和不同深度的病灶;三曲面探头的集成应用,提高了治疗效率,可以实现一次磁共振引导,多次消融不同区域的病灶,大大减少了患者的治疗时间和痛苦。To sum up, this embodiment uses three curvature probes integrated together, which increases the focusing depth of the ultrasonic focus and facilitates the treatment of different patients and lesions of different depths; the integrated application of the three-curved probes improves the treatment efficiency and can achieve One magnetic resonance guidance can ablate lesions in different areas multiple times, greatly reducing the patient's treatment time and pain.
以上详细描述了本发明的较佳具体实施例。应当理解,本领域的普通技术人员无需创造性劳动就可以根据本发明的构思作出诸多修改和变化。因此,凡本技术领域中技术人员依本发明的构思在现有技术的基础上通过逻辑分析、推理或者有限的实验可以得到的技术方案,皆应在由权利要求书所确定的保护范围内。 The preferred embodiments of the present invention are described in detail above. It should be understood that those skilled in the art can make many modifications and changes based on the concept of the present invention without creative efforts. Therefore, any technical solutions that can be obtained by those skilled in the art through logical analysis, reasoning or limited experiments based on the concept of the present invention and on the basis of the prior art should be within the scope of protection determined by the claims.

Claims (5)

  1. 一种用于磁波刀的超声探头装置,其特征在于,包括探头支架(1)、探头连接杆(2)和多个探头单元(3),所述探头连接杆(2)连接所述探头支架(1)的轴向一端,每个探头单元(3)上设有聚焦面(31)用于形成超声聚焦焦点,至少一个探头单元(3)和其它探头单元(3)的超声聚焦焦点深度不同,所述多个探头单元(3)安装在探头支架(1)上,使其聚焦面(31)分布在探头支架(1)的周向侧面。An ultrasonic probe device for magnetic wave knife, characterized in that it includes a probe holder (1), a probe connecting rod (2) and a plurality of probe units (3), and the probe connecting rod (2) is connected to the probe holder At one axial end of (1), each probe unit (3) is provided with a focusing surface (31) for forming an ultrasonic focusing focus. The ultrasonic focusing focus depths of at least one probe unit (3) and other probe units (3) are different. , the plurality of probe units (3) are installed on the probe holder (1), so that their focusing surfaces (31) are distributed on the circumferential side of the probe holder (1).
  2. 根据权利要求1所述的一种用于磁波刀的超声探头装置,其特征在于,多个探头单元(3)的聚焦面(31)的曲率半径互不相同。An ultrasonic probe device for magnetic wave knife according to claim 1, characterized in that the curvature radii of the focusing surfaces (31) of the plurality of probe units (3) are different from each other.
  3. 根据权利要求1所述的一种用于磁波刀的超声探头装置,其特征在于,所述探头支架(1)的周向分布有安装槽(11),所述探头单元(3)嵌入安装槽(11)中进行固定。An ultrasonic probe device for magnetic wave knife according to claim 1, characterized in that the probe holder (1) is circumferentially distributed with mounting grooves (11), and the probe unit (3) is embedded in the mounting groove. Fixed in (11).
  4. 根据权利要求1所述的一种用于磁波刀的超声探头装置,其特征在于,所述探头单元(3)的数量至少为两个。An ultrasonic probe device for magnetic wave knife according to claim 1, characterized in that the number of the probe units (3) is at least two.
  5. 根据权利要求1所述的一种用于磁波刀的超声探头装置,其特征在于,所述探头支架(1)和探头连接杆(2)通过螺纹连接。 An ultrasonic probe device for magnetic wave knife according to claim 1, characterized in that the probe holder (1) and the probe connecting rod (2) are connected through threads.
PCT/CN2023/103003 2022-07-01 2023-06-28 Ultrasonic probe apparatus for magnetic resonance-guided focus ultrasound WO2024002118A1 (en)

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