WO2023233532A1

WO2023233532A1 - Tube connection system and tube connector set

Info

Publication number: WO2023233532A1
Application number: PCT/JP2022/022164
Authority: WO
Inventors: 学司加藤; 順一桑原
Original assignee: 株式会社サンプラテック
Priority date: 2022-05-31
Filing date: 2022-05-31
Publication date: 2023-12-07

Abstract

Provided is a tube connection system that is suitable for aseptically connecting various tubes. The tube connection system A1 comprises: first and second holders 2A, 2B for holding first and second tube connectors 1A, 1B; a movement means 3 for moving the first and second holders 2A, 2B toward and away from each other; a heating means 4; and a withdrawal means 5. Each of the first and second tube connectors 1A, 1B includes a tube attachment section arranged on one side in a first direction x, a heat-weldable flange section 12 arranged on the other side in the first direction x, and a sealing body 16 that has higher thermal conductivity than the flange section 12 and covers the flange section 12. The first and second holders 2A, 2B are capable of holding the first and second tube connectors 1A, 1B with the sealing bodies 16 of the first and second tube connectors 1A, 1B facing each other. The heating means 4 is capable of heating each of the sealing bodies 16 of the first and second tube connectors 1A, 1B. The withdrawal means 5 makes it possible to withdraw each of the sealing bodies 16 of the first and second tube connectors 1A, 1B in a second direction y orthogonal to the first direction x.

Description

Tube connection systems and tube connector sets

The present disclosure relates to a tube connection system and tube connector set for aseptically connecting tubes.

Conventionally, devices for aseptically joining tubes are known. For example, Patent Document 1 discloses a tube joining device for joining two tubes. The tube joining device disclosed in the document includes a pair of clamps that hold two tubes at two locations with a gap between them, a cutting plate that cuts the two tubes, and a moving means that moves the clamps as appropriate. It is equipped with When joining tubes, first, two tubes are cut between a pair of clamps using a heated cutting plate, and the clamps are rotated so that the cut surfaces of the two tubes face each other. Next, by retracting the cutting plate and pressing the cut surfaces in a high temperature state against each other in the axial direction, the cut surfaces are welded together to form one tube. The above-mentioned tube joining device is used to aseptically join tubes when exchanging a dialysate bag and a waste fluid bag, for example.

The above-mentioned conventional tube joining device requires the clamp to be appropriately moved with high precision, leading to an increase in the complexity and size of the overall configuration of the device. Furthermore, if the diameters and materials of the two tubes to be joined are different, the tubes cannot be joined appropriately.

Patent No. 4262249

The present disclosure was devised under these circumstances, and its main objective is to provide a tube connection system suitable for aseptically connecting various tubes.

In order to solve the above problems, the present disclosure employs the following technical means.

A tube connection system provided by a first aspect of the present disclosure includes a first holder holding a first tube connector, a second holder holding a second tube connector, and the first holder and the second holder. The first tube connector and the second tube connector each include a moving means for moving toward and away from each other, a heating means, and a pulling means, and each of the first tube connector and the second tube connector is a tube disposed on one side in the first direction. a mounting portion, a flange portion disposed on the other side of the first direction and capable of being heat-welded, an internal flow path penetrating in the first direction from the tube mounting portion to the flange portion, and a sealing body that has high thermal conductivity and covers the flange portion, and the first holder and the second holder include the sealing body of each of the first tube connector and the second tube connector. are capable of holding the first tube connector and the second tube connector in opposing positions, and the heating means is capable of heating the sealing body of each of the first tube connector and the second tube connector. , the pulling means is capable of pulling out the sealing bodies of each of the first tube connector and the second tube connector in a second direction perpendicular to the first direction.

In a preferred embodiment, the device further includes the first tube connector and the second tube connector.

In a preferred embodiment, the moving means has a first position in which the sealing bodies of the first tube connector and the second tube connector are opposed to each other and are spaced apart from each other; a second position in which the sealing bodies of the second tube connector are in contact with each other, and a third position in which the flange portions of the first tube connector and the second tube connector are brought into pressure contact with each other, and the heating means heats the sealing body of each of the first tube connector and the second tube connector when in the second position, and the drawing means heats the sealing body of each of the first tube connector and the second tube connector when in the second position and pulling out the heated sealing body of each of the second tube connectors in the second direction.

In a preferred embodiment, the flange portion has an annular first end face facing the other side in the first direction, and an annular first end face facing the other side in the first direction from the first end face on the radially inner side of the first end face. a recessed flange, the flange recess surrounding the internal flow path when viewed in the first direction.

In a preferred embodiment, each of the first tube connector and the second tube connector includes an annular elastic body that is attached to the flange recess and has a higher temperature limit than the first end surface, and the annular elastic body has a heat resistance temperature higher than that of the first end surface. , a first through hole communicating with the internal flow path, and a second end surface that is located on the other side in the first direction than the first end surface in a natural state and faces the other side in the first direction. The sealing body covers the first end surface and the second end surface.

In a preferred embodiment, each of the first tube connector and the second tube connector includes an annular body that is attached to the flange recess and has a higher temperature limit than the first end surface, and the annular body has a heat resistance higher than that of the first end surface. It has a second through hole communicating with the internal flow path and a third end face facing the other side in the first direction, and the sealing body covers the first end face and the third end face.

In a preferred embodiment, each of the first holder and the second holder has a first mating shape, and each of the first tube connector and the second tube connector has a second mating shape. The first fitting shape and the second fitting shape can be fitted in a positioned state.

In a preferred embodiment, the apparatus further includes a sealed body recovery section for recovering the sealed body pulled out by the pulling means.

In a preferred embodiment, the sealing body includes a thin metal plate or a thin metal film.

In a preferred embodiment, the sealing body includes a first portion that overlaps the flange portion when viewed in the first direction, and a second portion that extends from the first portion in a direction perpendicular to the first direction. and has.

In a preferred embodiment, a non-slip structure is provided on a first surface of the second portion facing one side in the first direction.

A tube connector set provided by a second aspect of the present disclosure is a tube connector set that configures the tube connection system according to the first aspect of the present disclosure, and includes the first tube connector and the second tube connector. include.

Other features and advantages of the present disclosure will become more apparent from the detailed description given below with reference to the accompanying drawings.

1 is a front view showing a schematic configuration of a tube connection system according to an embodiment of the present disclosure. 1 is a front view showing a schematic configuration of a tube connection system according to an embodiment of the present disclosure. It is a perspective view of a 1st tube connector. 4 is a cross-sectional view taken along line IV-IV in FIG. 3. FIG. 5 is a sectional view taken along line VV in FIG. 4. FIG. It is a perspective view of a 2nd tube connector. 7 is a cross-sectional view taken along line VII-VII in FIG. 6. FIG. 8 is a cross-sectional view taken along line VIII-VIII in FIG. 7. FIG. FIG. 3 is a schematic perspective view for explaining a structure in which the first and second tube connectors are held by the first and second holders. FIG. 3 is a schematic perspective view for explaining a structure in which the first and second tube connectors are held by the first and second holders. It is a front view explaining the procedure of connecting the first and second tube connectors. It is a front view explaining the procedure of connecting the first and second tube connectors. It is a front view explaining the procedure of connecting the first and second tube connectors. FIG. 3 is a sectional view showing a connected state of first and second tube connectors. It is a sectional view showing a first modification of the first and second tube connectors. FIG. 7 is a cross-sectional view showing a connected state of first and second tube connectors according to a first modification. It is a sectional view showing a second modification of the first and second tube connectors. FIG. 7 is a cross-sectional view showing a connected state of first and second tube connectors according to a second modification. It is a sectional view showing a third modification of the first and second tube connectors. FIG. 7 is a sectional view showing a connected state of first and second tube connectors according to a third modification. It is a sectional view showing a fourth modification of the first and second tube connectors. It is a sectional view showing the connection state of the 1st and 2nd tube connector concerning the 4th modification. It is a perspective view which shows the 5th modification of a 1st and 2nd tube connector. It is a front view which shows the connection procedure of the 1st and 2nd tube connector based on the 5th modification. FIG. 1 is a schematic configuration diagram showing an example of a tube connector set according to the present disclosure.

Hereinafter, preferred embodiments of the present disclosure will be specifically described with reference to the drawings.

Terms such as "first," "second," and "third" in the present disclosure are merely used as labels and are not necessarily intended to attach any permutation to those objects.

1 and 2 illustrate a tube connection system according to an embodiment of the present disclosure. The tube connection system A1 of the present embodiment includes a first tube connector 1A, a second tube connector 1B, a first holder 2A, a second holder 2B, a moving means 3, a heating means 4, a drawing means 5, and a sealing body collecting section. It is equipped with 6. The tube connection system A1 connects a pair of tubes 7 attached to the first tube connector 1A and the second tube connector 1B via the first tube connector 1A and the second tube connector 1B. Although the use of the tube connection system A1 is not particularly limited, it is used, for example, in the field of cell culture to connect a medium storage bag and a cell culture bag. In this case, a culture medium storage bag is connected to one end of the pair of tubes 7, and a cell culture bag is connected to the other end.

The tube connection system A1 includes, for example, a connection device main body 9, and the first holder 2A, second holder 2B, moving means 3, heating means 4, and extraction means 5 are arranged at appropriate positions in the connection device main body 9. has been done. In the illustrated example, the connection device main body 9 includes a fixed housing 91 and a movable housing 92. The fixed side housing 91 is arranged on the left side in the figure and has a roughly U-shape. The movable housing 92 is disposed on the right side in the figure and has a roughly L-shape.

The first holder 2A is fixed to the upper part of the fixed housing 91. In the illustrated example, the first holder 2A is arranged at the upper right end of the fixed housing 91. The second holder 2B is fixed to the upper part of the movable housing 92. In the illustrated example, the second holder 2B is arranged at the upper left end of the movable housing 92. The first holder 2A and the second holder 2B are provided to protrude upward from the upper portions of the fixed housing 91 and the movable housing 92. As shown in FIG. 1, the first holder 2A and the second holder 2B are arranged adjacent to each other in the first direction x (left-right direction in the figure).

The first tube connector 1A is held by the first holder 2A. The second tube connector 1B is held by a second holder 2B. The first tube connector 1A held by the first holder 2A and the second tube connector 1B held by the second holder 2B are arranged adjacent to each other in the first direction x. Details of the first tube connector 1A, the second tube connector 1B, the first holder 2A, and the second holder 2B will be described later.

The moving means 3 moves the first holder 2A and the second holder 2B in a direction in which they approach and separate from each other (first direction x in the illustrated example). In the illustrated example, the moving means 3 includes a slide mechanism 31. The slide mechanism 31 is a rack and pinion mechanism that includes a drive gear 32 (pinion gear section) and a movable shaft 33 (rack gear section), and moves the movable shaft 33 in the first direction x. The drive gear 32 is disposed inside the fixed housing 91 and is rotationally driven by a drive source (not shown). The movable shaft 33 has a rack gear portion that meshes with the drive gear 32 (pinion gear portion). A portion of the movable shaft 33 on the left side in the figure is supported so as to be slidable along the first direction x with respect to the fixed housing 91. The right end portion of the movable shaft 33 in the figure is fixed to the movable housing 92. When the drive gear 32 is rotated by the drive source (not shown), the movable shaft 33 moves along the first direction x, thereby causing the first holder 2A and the second holder 2B to approach or separate from each other in the first direction x. is possible. FIG. 1 shows a state in which the first holder 2A and the second holder 2B are close to each other, and FIG. 2 shows a state in which the first holder 2A and the second holder 2B are separated from each other. Note that the specific configuration of the moving means 3 is not limited to the above. The moving means 3 may be constituted by an actuator using a power cylinder, for example, in addition to the gear mechanism as described above.

An operation switch 93 is provided at a suitable location on the fixed side housing 91. For example, by operating the operation switch 93, the moving means 3 is activated, and the first holder 2A and the second holder 2B are moved from a state where they are separated from each other (see FIG. 2) to a state where the first holder 2A and the second holder 2B are close to each other. (See Figure 1). Further, by operating the operation switch 93, the heating means 4 and the drawing means 5, which will be described later, are operated.

As shown in FIGS. 3 to 5, the first tube connector 1A has a tube attachment portion 11, a flange portion 12, a body portion 13, an internal flow path 14, a locking collar 15, and a sealing body 16. As shown in FIGS. 6 to 8, the second tube connector 1B has a tube attachment portion 11, a flange portion 12, a body portion 13, an internal flow path 14, a locking collar 15, and a sealing body 16. In this embodiment, the first tube connector 1A and the second tube connector 1B have the same structure. The details of the structure of the first tube connector 1A (second tube connector 1B) will be explained mainly with reference to FIGS. 3 to 5.

The tube attachment part 11 is arranged on one side of the first direction x (hereinafter referred to as "first direction one side x1" as appropriate). In the illustrated example, the tube attachment part 11 is configured as a barb joint, and the tube 7 can be attached by fitting the flexible tube 7 into the tube attachment part 11 by fitting it externally. Note that the shape of the tube attachment portion 11 is not limited to the illustrated example, and the tube 7 may be fitted into the tube attachment portion 11, for example. Alternatively, the tube 7 may be adhesively fixed in a state in which it is fitted externally or internally into the tube attachment part 11.

The flange portion 12 is spaced apart from the tube attachment portion 11 in the first direction x, and is disposed on the other side of the first direction x (hereinafter appropriately referred to as "the other side in the first direction x2"). The flange portion 12 is approximately disk-shaped. The body portion 13 connects the tube attachment portion 11 and the flange portion 12 in the first direction x. In the illustrated example, the body 13 has a block shape with a generally rectangular cross section. The internal flow path 14 is a through hole that penetrates in the first direction x from the tube attachment part 11 to the flange part 12. The locking collar 15 is a part that locks the first holder 2A (second holder 2B) in a proper position. In the illustrated example, a pair of locking collars 15 are provided that extend horizontally (direction perpendicular to the first direction x) from one end x1 of the body 13 in the first direction.

The flange portion 12 has an end surface 120 facing the other side x2 in the first direction. The end surface 120 is annular. At least the end surface 120 of the flange portion 12 is made of a heat-weldable material. In this embodiment, the tube attachment part 11, the flange part 12, the body part 13, and the pair of locking collars 15 are integrally formed of heat-weldable synthetic resin. Examples of heat-weldable resin materials include, but are not limited to, relatively low-melting thermoplastic resins such as polyethylene and polyolefin elastomer (POE). Unlike this embodiment, a portion of the flange portion 12 including the end surface 120 may be made of a heat-weldable material, and other portions may be made of a different material (for example, a resin material or a metal material with a higher heat resistance temperature). good. In the illustrated example, the body 13 is shaped like a rectangular block, but from the viewpoint of preventing shrinkage during resin molding, appropriate recesses are provided in the body 13 to make the thickness of each part of the body 13 uniform. It may be configured as desired.

The sealing body 16 is a member that covers the flange portion 12 and has higher thermal conductivity than the flange portion 12. The sealing body 16 includes a thin metal plate or a thin metal film. In this embodiment, the sealing body 16 is constituted by a laminate including a metal thin film. The sealing body 16 has a structure in which a resin film as a heat seal layer is laminated on aluminum foil, which is a thin metal film, for example. The heat-sealing layer of the sealing body 16 is in close contact with the end surface 120 of the flange portion 12 by thermal welding and covers the end surface 120.

Note that, unlike this embodiment, the sealing body 16 may have a structure in which a metal thin film is applied to a heat-sealable resin film, such as an aluminum vapor-deposited film, by means of coating, plating, painting, or the like. Further, the sealing body 16 may be formed of a thin metal plate or a single metal thin film. In this case, for example, the sealing body 16 (a single metal thin plate or a single metal thin film) and the end surface 120 of the flange portion 12 are joined by welding. The material of the metal thin plate is not particularly limited, and for example, a copper thin plate or an aluminum thin plate can be used. Furthermore, the sealing body 16 may have a structure that does not include a thin metal plate or a thin metal film. The sealing body 16 may be formed of a thin plate made of a ceramic material having high thermal conductivity, such as alumina.

The sealing body 16 includes a first part 161 and a second part 162. The first portion 161 is a portion that overlaps the flange portion 12 when viewed in the first direction x. In this embodiment, the first portion 161 is thermally welded to the end surface 120 of the flange portion 12 and covers the end surface 120. The second portion 162 is connected to the first portion 161 and extends from the first portion 161 in a direction perpendicular to the first direction x (downward in FIGS. 4 and 7).

9 and 10 are schematic perspective views for explaining the holding structure of the first tube connector 1A and the second tube connector 1B by the first holder 2A and the second holder 2B. As shown in FIG. 9, the first holder 2A and the second holder 2B each have a connector receiving part 21 and a lid part 22. The connector receiving portion 21 has a rectangular shape with an open upper part. The lid part 22 is rotatably connected to a suitable position of the connector receiving part 21. The lid part 22 can rotate around the axis along the first direction x and close the upper part of the connector receiving part 21.

In this embodiment, as shown in FIG. 9, each of the first holder 2A and the second holder 2B has a first fitting shape F1. Each of the first tube connector 1A and the second tube connector 1B has a second fitting shape F2. The first fitting shape F1 and the second fitting shape F2 can be fitted into each other.

In the present embodiment, the connector receiving portion 21 (a rectangular portion with an open upper part) in each of the first holder 2A and the second holder 2B is included in the first fitting shape F1. Further, the flange portion 12, body portion 13, and pair of locking collars 15 in each of the first tube connector 1A and the second tube connector 1B are included in the second fitting shape F2.

The dimension of the body portion 13 in the first direction x (the gap between the flange portion 12 and the locking collar 15 in the first direction x) is approximately the same as the dimension of the connector receiving portion 21 in the first direction x. The dimension of the body portion 13 in the horizontal direction perpendicular to the first direction x is approximately the same as the gap of the connector receiving portion 21 in the horizontal direction perpendicular to the first direction x. As a result, as shown in FIG. 10, when the first tube connector 1A (second tube connector 1B) is set in the first holder 2A (second holder 2B), the first fitting shape F1 and the second fitting shape It fits into the shape F2 in a positioned state. Therefore, the first tube connector 1A (second tube connector 1B) can be positioned with respect to the first holder 2A (second holder 2B) in a direction perpendicular to the first direction x and in a rotational direction around the first direction x. is being done. As shown in FIG. 10, the first holder 2A and the second holder 2B are arranged in such a manner that the sealing bodies 16 of the first tube connector 1A and the second tube connector 1B face each other. It is possible to hold the tube connector 1B. Note that the first fitting shape F1 in the first holder 2A and the second holder 2B and the second fitting shape F2 in the first tube connector 1A and the second tube connector 1B are limited to the illustrated shapes of this embodiment. This is not a complete set and can be changed as appropriate.

The heating means 4 is for heating each sealing body 16 of the first tube connector 1A and the second tube connector 1B. In the illustrated example, the heating means 4 includes, for example, a heat source 41, a heating body 42, and a heat transfer section 43, as shown in FIGS. 1 and 11. The specific configuration of the heating source 41 is not particularly limited, but for example, a heater using a resistor that generates heat when an electric current is passed (nichrome wire heater or ceramic heater), frictional heat due to ultrasonic vibration, electromagnetic induction heating, etc. may be used as appropriate. Can be used. The heating body 42 is made of, for example, a metal rod with excellent thermal conductivity, and the tip of the heating body 42 is in contact with the sealing body 16 . The heat transfer section 43 is in contact with both the heating source 41 and the heating body 42, and is made of a material with excellent thermal conductivity. As shown in FIG. 1, when the first holder 2A and the second holder 2B are close to each other, the sealing bodies 16 of the first tube connector 1A and the second tube connector 1B are in contact with each other. The temperature of the sealing body 16 is increased by heat transmitted from the heat source 41 via the heat transfer section 43 and the heating body 42 .

The pulling means 5 is for pulling out the sealing bodies 16 of each of the first tube connector 1A and the second tube connector 1B. In the illustrated example, the pulling means 5 includes a drive gear 51, a first gear 52, a first roller 53, and a second roller 54. The drive gear 51 is disposed inside the fixed housing 91 and is rotationally driven by a drive source (not shown). The first gear 52 and the first roller 53 are integrally connected and arranged inside the fixed housing 91. The first gear 52 meshes with the drive gear 51, and when the drive gear 51 is driven to rotate, the first gear 52 and the first roller 53 are driven to rotate in the opposite direction to the drive gear 51. The second roller 54 is disposed inside the movable housing 92 and is rotatably supported by the movable housing 92. The first roller 53 and the second roller 54 are for pulling out the sealing body 16 of the first tube connector 1A and the second tube connector 1B, respectively. When the first tube connector 1A is held by the first holder 2A, the first roller 53 contacts the second portion 162 of the sealing body 16 in the first tube connector 1A. Similarly, when the second tube connector 1B is held by the second holder 2B, the second roller 54 comes into contact with the second portion 162 of the sealing body 16 in the second tube connector 1B. Although the details will be described later, as shown in FIG. It can be pulled out in the middle-down direction).

The sealing body collecting section 6 is for recovering the sealing body 16 pulled out by the pulling means 5. As shown in FIG. 1, the sealing body recovery unit 6 is arranged in the second direction y (downward in the figure) with respect to each sealing body 16 of the first tube connector 1A and the second tube connector 1B. There is. In the illustrated example, the sealing body recovery unit 6 is fixed to a stationary housing 91, and is, for example, a case body made of transparent resin and having an opening 61 at the top.

Next, a procedure for connecting the first tube connector 1A and the second tube connector 1B using the tube connection system A1 will be described with reference to FIGS. 11 to 13.

As shown in FIG. 11, the first tube connector 1A and the second tube connector 1B are set in the first holder 2A and the second holder 2B in advance. In the state shown in FIG. 11, the sealing bodies 16 of the first tube connector 1A and the second tube connector 1B face each other and are separated from each other in the first direction x. The arrangement of the first tube connector 1A and the second tube connector 1B shown in FIG. 11 corresponds to an example of the "first position" of the present disclosure.

Next, the moving means 3 is operated to bring the first holder 2A and the second holder 2B close to each other, as shown in FIG. In the state shown in FIG. 12, the sealing bodies 16 of the first tube connector 1A and the second tube connector 1B are in contact with each other. In the illustrated example, the first portions 161 of the sealing body 16 sandwiched between the flange portions 12 of the first tube connector 1A and the second tube connector 1B are in pressure contact with each other. Further, the second portions 162 of the sealing bodies 16 of the first tube connector 1A and the second tube connector 1B are sandwiched between the first roller 53 and the second roller 54, and are pressed against each other. Here, the heating means 4 heats each sealing body 16 of the first tube connector 1A and the second tube connector 1B via the heating body 42. As a result, the temperature of the sealing body 16 and each end surface 120 of the flange portion 12 covered with the sealing body 16 increases, and the respective end surfaces 120 are heated to a state where they can be thermally welded. The arrangement of the first tube connector 1A and the second tube connector 1B shown in FIG. 12 corresponds to an example of the "second position" of the present disclosure.

Note that in the illustrated example, a pair of heating bodies 42 that individually abuts on each of the sealing bodies 16 of the first tube connector 1A and the second tube connector 1B are provided, but the present disclosure is not limited thereto. For example, one heating body 42 that contacts the sealing body 16 of the first tube connector 1A is provided, and the single heating body 42 causes the sealing bodies 16 of the first tube connector 1A and the second tube connector 1B that are in pressure contact with each other to be heated. Each may be heated.

Next, the pulling means 5 is operated to pull out the sealing body 16. Specifically, in the state shown in FIG. 12, the first roller 53 is rotated clockwise. Here, the second roller 54 receives a reaction force from the pair of sealing bodies 16 sandwiched between it and the first roller 53, and rotates in the opposite direction (counterclockwise) to the first roller 53. Then, as shown in FIG. 13, the heated pair of sealing bodies 16 are pulled out in the second direction y (downward in the figure). The pair of sealed bodies 16 that have been pulled out are collected by the sealed body collecting section 6 shown in FIG. Further, at the same time as the pair of sealing bodies 16 are pulled out, the second holder 2B is moved toward the first holder 2A by the operation of the moving means 3, and the flanges of each of the first tube connector 1A and the second tube connector 1B are moved. The portions 12 are pressed against each other. As described with reference to FIG. 12, each end surface 120 of the flange portion 12 is heated to a state where thermal welding is possible, and the end surfaces 120 of the flange portion 12 that are pressed together are joined by thermal welding. In this way, the flange portions 12 of the first tube connector 1A and the second tube connector 1B are connected to each other. Thereafter, the first tube connector 1A and the second tube connector 1B are removed from the first holder 2A and the second holder 2B. Note that the arrangement of the first tube connector 1A and the second tube connector 1B shown in FIG. 13 corresponds to an example of the "third position" of the present disclosure.

Note that in the illustrated example, the pair of sealing bodies 16 are pulled out by the first roller 53 and the second roller 54, but the present disclosure is not limited to this. The pulling means 5 may be constituted by an actuator such as a solenoid (electromagnetic valve), and may pull out the pair of sealing bodies 16 while clamping them.

FIG. 14 shows the connected state of the first tube connector 1A and the second tube connector 1B. As shown in FIG. 14, by connecting the flange portions 12 of the first tube connector 1A and the second tube connector 1B, the internal flow path 14 of the first tube connector 1A and the internal flow path of the second tube connector 1B are connected. 14 is in communication. A pair of left and right tubes 7 attached to the tube attachment portions 11 of the first tube connector 1A and the second tube connector 1B are connected via the first tube connector 1A and the second tube connector 1B. In addition, in FIG. 14, for convenience of drawing, the end surface 120 of each flange portion 12 of the first tube connector 1A and the second tube connector 1B is clearly shown. It is considered that the thickness of the end surfaces 120 is actually changed to be thinner because the end surfaces 120 are integrally joined by thermal welding as described above. This also applies to modified examples and the like that will be described later.

Next, the operation of this embodiment will be explained.

In the tube connection system A1 of this embodiment, the first holder 2A holding the first tube connector 1A and the second holder 2B holding the second tube connector 1B are moved close to and separated from each other by the moving means 3. It is possible to move in the direction. The first tube connector 1A and the second tube connector 1B each include a tube attachment portion 11 disposed on one side x1 in the first direction, a flange portion 12 disposed on the other side x2 in the first direction, and a tube attachment portion 11 disposed on the other side x2 in the first direction. It has an internal flow path 14 penetrating in the first direction x from the flange portion 12 to the flange portion 12, and a sealing body 16 that covers the flange portion 12. The flange portion 12 can be thermally welded, and the sealing body 16 has higher thermal conductivity than the flange portion 12. The sealing bodies 16 of the first tube connector 1A and the second tube connector 1B held by the first holder 2A and the second holder 2B are arranged to face each other. Further, each of the sealing bodies 16 of the first tube connector 1A and the second tube connector 1B can be heated by the heating means 4, and can be heated in a direction perpendicular to the first direction x (second direction y) by the pulling means 5. It is removable. According to such a configuration, by appropriately operating the moving means 3, the heating means 4, and the pulling means 5, the first tube connector 1A and the second tube connector The heated flange parts 12 of 1B can be joined together by thermal welding. The flange portions 12 are joined together at the same time as the sealing body 16 is pulled out. Therefore, the flange portions 12 of the first tube connector 1A and the second tube connector 1B are connected to each other in a sterile manner without bacteria or foreign matter entering from the outside air. As a result, the pair of tubes 7 attached to the tube attachment portions 11 of the first tube connector 1A and the second tube connector 1B can be connected aseptically via the first tube connector 1A and the second tube connector 1B. is possible.

In the first tube connector 1A and the second tube connector 1B of the tube connection system A1, the pair of tubes 7 attached to the tube attachment part 11 can be made of different materials as appropriate. Therefore, according to this embodiment, a pair of tubes 7 made of different materials can be appropriately joined via the first tube connector 1A and the second tube connector 1B.

The first holder 2A holding the first tube connector 1A and the second holder 2B holding the second tube connector 1B are relatively moved only in the first direction x by the moving means 3. According to the tube connection system A1 having such a configuration, the overall configuration can be simplified and downsized.

In this embodiment, unlike the configuration disclosed in Patent Document 1, the first holder 2A and the second holder 2B are easily designed to protrude from the connection device main body 9, so even a short tube 7 can be easily set. Therefore, it is possible to set the length of the tube 7 short in advance, and it is possible to suppress loss of the contents of the container or the like (medium, etc. in cell culture applications) connected to the end of the tube 7.

FIG. 15 shows a first modification of the first tube connector 1A and second tube connector 1B shown in the above embodiment. FIG. 15 is a sectional view of a first tube connector 101A and a second tube connector 101B according to a first modification, and is a sectional view similar to FIGS. 4 and 7. In the drawings from FIG. 15 onward, elements that are the same as or similar to the first tube connector 1A (second tube connector 1B) of the above embodiment are given the same reference numerals as those of the above embodiment, and explanations will be given as appropriate. Omitted. Further, the configurations of each part in each modification example etc. after FIG. 15 can be appropriately combined with each other within a range that does not cause technical contradiction.

In this modification, the first tube connector 101A and the second tube connector 101B have the same structure. Each flange portion 12 of the first tube connector 101A and the second tube connector 101B has a first end surface 121 and a flange recess 122. The first end surface 121 faces the other side x2 in the first direction and is an annular plane. The flange recess 122 is recessed from the first end surface 121 toward one side x1 in the first direction on the radially inner side of the first end surface 121 . In this modification, the diameter of the tube attachment part 11 and the diameter of the internal flow path 14 are smaller than those of the first tube connector 1A and the second tube connector 1B of the above embodiment. The diameter of the tube 7 attached to the tube attachment part 11 is smaller than that of the above embodiment.

The diameter of the flange recess 122 is larger than the diameter of the internal flow path 14, and the flange recess 122 surrounds the internal flow path 14 when viewed in the first direction x. The first tube connector 101A and the second tube connector 101B of this modification are connected by the same procedure as the first tube connector 1A and the second tube connector 1B of the above embodiment described with reference to FIGS. 11 to 13. can be connected to each other.

FIG. 16 shows the connected state of the first tube connector 101A and the second tube connector 101B. As shown in FIG. 16, by connecting the flange portions 12 of the first tube connector 101A and the second tube connector 101B, the internal flow path 14 of the first tube connector 101A and the internal flow path of the second tube connector 101B are connected. 14 communicate with each other via the flange recess 122. A pair of tubes 7 attached to the tube attachment portions 11 of the first tube connector 101A and the second tube connector 101B are connected via the first tube connector 101A and the second tube connector 101B. The flange portions 12 of the first tube connector 101A and the second tube connector 101B are connected to each other in a sterile manner without introducing bacteria or foreign matter from the outside air. Thereby, the pair of tubes 7 attached to the tube attachment portions 11 of the first tube connector 101A and the second tube connector 101B can be connected aseptically via the first tube connector 101A and the second tube connector 101B. is possible.

In this modification, the flange portion 12 has a first end surface 121 and a flange recess 122. The flange recess 122 is recessed from the first end surface 121 toward one side x1 in the first direction on the radially inner side of the first end surface 121 . The flange recess 122 surrounds the internal channel 14 when viewed in the first direction x. According to the configuration having such a flange recess 122, when the sealing body 16 covering the first end surface 121 of the flange portion 12 is pulled out, even if a film-like burr is generated by the melted resin on the first end surface 121, , it is possible to prevent problems such as the burr blocking the internal flow path 14 . In addition, there are effects similar to those of the above embodiment.

FIG. 17 shows a second modification of the first tube connector 1A and the second tube connector 1B shown in the above embodiment. FIG. 17 is a sectional view of a first tube connector 102A and a second tube connector 102B according to a second modification, and is a sectional view similar to FIGS. 4 and 7.

In this modification, the first tube connector 102A has the same structure as the first tube connector 1A of the above embodiment, and the second tube connector 102B has the same structure as the second tube connector 101B of the above modification. The flange portion 12 of the second tube connector 102B has a first end surface 121 and a flange recess 122. The diameter of the tube attachment portion 11 and the diameter of the internal flow path 14 in the second tube connector 102B are smaller than those in the first tube connector 102A. The diameter of the tube 7 attached to the tube attachment part 11 of the second tube connector 102B is smaller than the diameter of the tube 7 attached to the tube attachment part 11 of the first tube connector 102A. The first tube connector 102A and the second tube connector 102B of this modification are connected by the same procedure as the first tube connector 1A and the second tube connector 1B of the above embodiment described with reference to FIGS. 11 to 13. can be connected to each other.

FIG. 18 shows the connected state of the first tube connector 102A and the second tube connector 102B. As shown in FIG. 18, by connecting the flange portions 12 of the first tube connector 102A and the second tube connector 102B, the internal flow path 14 of the first tube connector 102A and the internal flow path of the second tube connector 102B are connected. 14 communicate with each other via the flange recess 122. A pair of tubes 7 attached to the tube attachment portions 11 of the first tube connector 102A and the second tube connector 102B are connected via the first tube connector 102A and the second tube connector 102B. The flange portions 12 of the first tube connector 102A and the second tube connector 102B are connected to each other in a sterile manner without introducing bacteria or foreign matter from the outside air. Thereby, the pair of tubes 7 attached to the tube attachment portions 11 of the first tube connector 102A and the second tube connector 102B can be connected aseptically via the first tube connector 102A and the second tube connector 102B. is possible.

In this modification, the diameter of the tube attachment part 11 in the second tube connector 102B is smaller than the diameter of the tube attachment part 11 in the first tube connector 102A. According to such a configuration, it is possible to appropriately connect a pair of tubes 7 having different diameters in a sterile manner via the first tube connector 102A and the second tube connector 102B. In addition, there are effects similar to those of the above embodiment.

FIG. 19 shows a third modification of the first tube connector 1A and the second tube connector 1B shown in the above embodiment. FIG. 19 is a sectional view of a first tube connector 103A and a second tube connector 103B according to a third modification, and is a sectional view similar to FIGS. 4 and 7.

As shown in FIG. 19, the flange portion 12 of each of the first tube connector 103A and the second tube connector 103B has a first end surface, similar to the first tube connector 101A and the second tube connector 101B of the first modification. 121 and a flange recess 122. In this modification, each of the first tube connector 103A and the second tube connector 103B includes an annular elastic body 17 mounted in a flange recess 122. The annular elastic body 17 has a first through hole 171 and a second end surface 172. The first through hole 171 communicates with the internal flow path 14 . The second end surface 172 faces the other side x2 in the first direction, and is located closer to the other side x2 in the first direction than the first end surface 121 of the flange portion 12 in a natural state. The sealing body 16 (first portion 161) covers the first end surface 121 of the flange portion 12 and the second end surface 172 of the annular elastic body 17. The annular elastic body 17 has a higher temperature limit than the flange portion 12 (first end surface 121). The annular elastic body 17 is made of an elastically deformable soft material. The constituent material of the annular elastic body 17 is not particularly limited, but silicone rubber may be used, for example. The first tube connector 103A and the second tube connector 103B of this modification are connected by the same procedure as the first tube connector 1A and the second tube connector 1B of the above embodiment described with reference to FIGS. 11 to 13. can be connected to each other.

FIG. 20 shows the connected state of the first tube connector 103A and the second tube connector 103B. As shown in FIG. 20, by connecting the flange portions 12 of the first tube connector 103A and the second tube connector 103B, the internal flow path 14 of the first tube connector 103A and the internal flow path of the second tube connector 103B are connected. 14 communicate with each other through the first through hole 171. A pair of tubes 7 attached to the tube attachment portions 11 of the first tube connector 103A and the second tube connector 103B are connected via the first tube connector 103A and the second tube connector 103B. The flange portions 12 of the first tube connector 103A and the second tube connector 103B are connected to each other in a sterile manner without bacteria or foreign matter entering from the outside air. As a result, the pair of tubes 7 attached to the tube attachment portions 11 of the first tube connector 103A and the second tube connector 103B can be connected aseptically via the first tube connector 103A and the second tube connector 103B. is possible.

In this modification, the annular elastic body 17 is attached to the flange recess 122, and the second end surface 172 of the annular elastic body 17 is on the other side x2 in the first direction than the first end surface 121 of the flange portion 12 in the natural state. It stands out. According to such a configuration, in the connected state of the first tube connector 103A and the second tube connector 103B shown in FIG. 121) are joined by thermal welding. The annular elastic bodies 17 of the first tube connector 103A and the second tube connector 103B are mutually compressed, and the second end surfaces 172 are in pressure contact with each other. According to this modification, the annular elastic body 17 improves the sealing performance of the connection site between the first tube connector 103A and the second tube connector 103B, and it is possible to appropriately prevent leakage of fluid, etc. at the connection site. . In addition, there are effects similar to those of the above embodiment.

FIG. 21 shows a fourth modification of the first tube connector 1A and the second tube connector 1B shown in the above embodiment. FIG. 21 is a sectional view of a first tube connector 104A and a second tube connector 104B according to a fourth modification, and is a sectional view similar to FIGS. 4 and 7.

As shown in FIG. 21, the flange portion 12 of each of the first tube connector 104A and the second tube connector 104B has a first end surface, similar to the first tube connector 101A and the second tube connector 101B of the first modification. 121 and a flange recess 122. In this modification, each of the first tube connector 104A and the second tube connector 104B includes an annular body 18 mounted in a flange recess 122. The annular body 18 has a second through hole 181 and a third end surface 182. The second through hole 181 communicates with the internal flow path 14 . The third end surface 182 faces the other side x2 in the first direction. The sealing body 16 (first portion 161) covers the first end surface 121 of the flange portion 12 and the third end surface 182 of the annular body 18. The annular body 18 only needs to have a higher allowable temperature limit than the flange portion 12 (first end surface 121), and the constituent material of the annular body 18 is not particularly limited. For example, if the constituent material of the flange portion 12 (first end surface 121) is polyethylene, the constituent material of the annular body 18 may be polypropylene, which has a higher heat resistance temperature (higher melting point) than polyethylene. The first tube connector 104A and the second tube connector 104B of this modification are connected by the same procedure as the first tube connector 1A and the second tube connector 1B of the above embodiment described with reference to FIGS. 11 to 13. can be connected to each other.

FIG. 22 shows the connected state of the first tube connector 104A and the second tube connector 104B. As shown in FIG. 22, by connecting the flange portions 12 of the first tube connector 104A and the second tube connector 104B, the internal flow path 14 of the first tube connector 104A and the internal flow path of the second tube connector 104B are connected. 14 communicate with each other via the second through hole 181. A pair of tubes 7 attached to the tube attachment portions 11 of the first tube connector 104A and the second tube connector 104B are connected via the first tube connector 104A and the second tube connector 104B. The flange portions 12 of the first tube connector 104A and the second tube connector 104B are connected to each other in a sterile manner without contamination by outside air or foreign matter. Thereby, the pair of tubes 7 attached to the tube attachment portions 11 of the first tube connector 104A and the second tube connector 104B can be connected aseptically via the first tube connector 104A and the second tube connector 104B. is possible.

In this modification, the annular body 18 is attached to the flange recess 122, and the first end surface 121 of the flange portion 12 and the third end surface 182 of the annular body 18 are covered with the sealing body 16 (first portion 161). It is being said. According to such a configuration, even if burrs are generated by the melted resin on the first end surface 121 when the sealing body 16 covering the first end surface 121 of the flange portion 12 is pulled out, the first end surface 121 is not covered with burrs. The third end surface 182 (annular body 18) located on the radially inner side can prevent the burr from extending like a film, thereby preventing problems such as blocking the second through hole 181 communicating with the internal flow path 14. In addition, there are effects similar to those of the above embodiment.

FIG. 23 shows a fifth modification of the first tube connector 1A and the second tube connector 1B shown in the above embodiment. FIG. 23 is a perspective view of a first tube connector 105A and a second tube connector 105B according to a fifth modification, and is a perspective view similar to FIG. 9.

As shown in FIG. 23, in each of the sealing bodies 16 of the first tube connector 103A and the second tube connector 103B, a plurality of convex portions are provided on the first surface 163 of the second portion 162 facing one side x1 in the first direction. A section 164 is provided. The plurality of convex portions 164 are arranged at intervals from each other in the second direction y. Each of the plurality of convex portions 164 is a band-shaped protrusion extending in a direction perpendicular to both the first direction x and the second direction y.

FIG. 24 is a front view similar to FIG. 12, showing the connection procedure of the first tube connector 105A and the second tube connector 105B of this modification. As shown in FIG. 24, the surfaces of each of the first roller 53 and the second roller 54 are pressed against a convex portion 164 provided on each of the pair of sealing bodies 16. According to such a configuration, the grip force when pulling out the pair of sealing bodies 16 by the first roller 53 and the second roller 54 is increased, and the plurality of convex portions 164 provided on the first surface 163 are It exhibits an anti-slip effect when the pair of sealing bodies 16 are pulled out. The plurality of convex portions 164 provided on the first surface 163 are an example of the "non-slip structure" of the present disclosure. Note that the specific configuration of the anti-slip structure is not limited to the above-mentioned convex portion 164. The anti-slip structure can be achieved by roughening the first surface 163 by, for example, texturing, embossing, blasting, etching, printing, painting, coating, adhesion of different materials, welding of different materials, or inserts of different materials. It can take various forms such as molding.

FIG. 25 is a schematic configuration diagram showing an example of a tube connector set that constitutes the tube connection system according to the present disclosure. The tube connector set B1 shown in FIG. 25 includes a first tube connector 1A and a second tube connector 1B. In the illustrated example, the tube connector set B1 includes a pair of tubes 7, a culture medium storage bag 81, and a cell culture bag 82 in addition to the first tube connector 1A and the second tube connector 1B.

The culture medium storage bag 81 is connected to the end of one tube 7 attached to the first tube connector 1A. A medium (culture solution) is stored inside the medium storage bag 81 . A tube 71 is provided in the culture medium storage bag 81 . The medium in the medium storage bag 81 is injected through the tube 71 in a sterile environment, and a seal portion 711 is formed at the tip of the tube 71, which is closed by heat welding after the medium is injected. A pump P is connected to the end of the other tube 7 attached to the second tube connector 1B. Cell culture bag 82 is connected to pump P via tube 72. The tube 72 is a medium inflow path. A tube 73 is connected to the cell culture bag 82. Tube 73 is a discharge path for the medium inside cell culture bag 82 . For example, a waste liquid bag (not shown) is connected to the end of the tube 73.

The first tube connector 1A and the second tube connector 1B constituting the tube connector set B1 follow the connection procedure of the first tube connector 1A and the second tube connector 1B of the above embodiment described with reference to FIGS. 11 to 13. They can be connected to each other aseptically using a similar procedure. According to the tube connector set B1, after the first tube connector 1A and the second tube connector 1B are connected in a sterile manner, the first tube connector 1A, the second tube connector 1B and the pump P are removed from the culture medium storage bag 81. By supplying a culture medium to the cell culture bag 82 using the above method, cell culture can be performed in the cell culture bag 82 .

Although FIG. 25 shows a specific configuration example of the tube connector set B1, the configuration of the tube connector set of the present disclosure is not limited to this. Various bags and containers can be appropriately selected and connected to the ends of the pair of tubes 7 attached to the first tube connector 1A and the second tube connector 1B.

Although specific embodiments of the present invention have been described above, the present invention is not limited thereto, and various changes can be made without departing from the spirit of the invention. The specific configuration of each part of the tube connection system according to the present invention can be modified in various ways.

The present disclosure includes configurations related to the following additional notes.

[Appendix 1]
a first holder that holds the first tube connector; and a second holder that holds the second tube connector;
a moving means for moving the first holder and the second holder in directions toward and away from each other;
heating means;
and a means for extracting;
The first tube connector and the second tube connector each include a tube attachment portion disposed on one side in the first direction, a flange portion disposed on the other side in the first direction and heat weldable; an internal flow path penetrating in the first direction from the tube attachment part to the flange part, and a sealing body having higher thermal conductivity than the flange part and covering the flange part,
The first holder and the second holder are capable of holding the first tube connector and the second tube connector in a posture in which the sealing bodies of each of the first tube connector and the second tube connector face each other. ,
The heating means is capable of heating the sealing body of each of the first tube connector and the second tube connector,
The tube connection system, wherein the pulling means is capable of pulling out the sealing bodies of each of the first tube connector and the second tube connector in a second direction perpendicular to the first direction.
[Appendix 2]
The tube connection system according to supplementary note 1, further comprising the first tube connector and the second tube connector.
[Appendix 3]
The moving means includes a first position in which the sealing bodies of the first tube connector and the second tube connector are arranged facing each other and separated from each other; a second position in which the sealing bodies are brought into contact with each other, and a third position in which the flange portions of the first tube connector and the second tube connector are brought into pressure contact with each other,
The heating means heats the sealing body of each of the first tube connector and the second tube connector when in the second position,
The tube connection system according to appendix 2, wherein the pulling means pulls out the heated sealing bodies of each of the first tube connector and the second tube connector in the second direction when in the second position. .
[Appendix 4]
The flange portion has an annular first end face facing the other side in the first direction, and a flange recess that is recessed from the first end face toward one side in the first direction on the radially inner side of the first end face. death,
4. The tube connection system according to claim 2 or 3, wherein the flange recess surrounds the internal flow path when viewed in the first direction.
[Appendix 5]
Each of the first tube connector and the second tube connector includes an annular elastic body that is attached to the flange recess and has a higher temperature limit than the first end surface,
The annular elastic body has a first through hole communicating with the internal flow path, and a second through hole that is located on the other side in the first direction than the first end surface in a natural state and faces the other side in the first direction. having an end surface;
The tube connection system according to appendix 4, wherein the sealing body covers the first end surface and the second end surface.
[Appendix 6]
Each of the first tube connector and the second tube connector includes an annular body that is attached to the flange recess and has a higher temperature limit than the first end surface,
The annular body has a second through hole communicating with the internal flow path, and a third end face facing the other side in the first direction,
The tube connection system according to appendix 4, wherein the sealing body covers the first end surface and the third end surface.
[Appendix 7]
Each of the first holder and the second holder has a first fitting shape,
each of the first tube connector and the second tube connector has a second fitting shape;
The tube connection system according to any one of appendices 2 to 6, wherein the first fitting shape and the second fitting shape can be fitted in a positioned state.
[Appendix 8]
The tube connection system according to any one of Supplementary Notes 2 to 7, further comprising a sealing body collecting section for recovering the sealing body pulled out by the pulling means.
[Appendix 9]
9. The tube connection system according to any one of appendices 2 to 8, wherein the sealing body includes a thin metal plate or a thin metal film.
[Appendix 10]
Supplementary Note 2, wherein the sealing body has a first portion that overlaps the flange portion when viewed in the first direction, and a second portion that extends from the first portion in a direction perpendicular to the first direction. 10. The tube connection system according to any one of 1 to 9.
[Appendix 11]
The tube connection system according to appendix 10, wherein a non-slip structure is provided on a first surface of the second portion facing one side in the first direction.
[Appendix 12]
A tube connector set constituting the tube connection system according to any one of appendices 2 to 11,
A tube connector set including the first tube connector and the second tube connector.

A1: Tube connection system, B1: Tube connector set, 1A, 101A, 102A, 103A, 104A, 105A: 1st tube connector, 1B, 101B, 102B, 103B, 104B, 105B: 2nd tube connector, 11: Tube installation part, 12: flange part, 120: end face, 121: first end face, 122: flange recess, 13: body part, 14: internal channel, 15: locking collar, 16: sealing body, 161: first part , 162: second part, 163: first surface, 164: convex part (non-slip structure), 17: annular elastic body, 171: first through hole, 172: second end surface, 18: annular body, 181: first 2 through hole, 182: third end surface, 2A: first holder, 2B: second holder, 3: moving means, 31: slide mechanism, 32: drive gear, 33: movable shaft, 4: heating means, 41: heating source, 42: heating body, 43: heat transfer section, 5: extraction means, 51: drive gear, 52: first gear, 53: first roller, 54: second roller, 6: sealing body recovery section, 61 : Opening, 7, 71, 72, 73: Tube, 711: Seal part, 81: Medium storage bag, 82: Cell culture bag, 9: Connection device main body, 91: Fixed side housing, 92: Movable side housing, 93: operation switch, F1: first fitting shape, F2: second fitting shape, P: pump, x: first direction, x1: one side in first direction, x2: other side in first direction, y: second side 2 directions

Claims

a first holder that holds the first tube connector; and a second holder that holds the second tube connector;
a moving means for moving the first holder and the second holder in directions toward and away from each other;
heating means;
and a means for extracting;
The first tube connector and the second tube connector each include a tube attachment portion disposed on one side in the first direction, a flange portion disposed on the other side in the first direction and heat weldable; an internal flow path penetrating in the first direction from the tube attachment part to the flange part, and a sealing body having higher thermal conductivity than the flange part and covering the flange part,
The first holder and the second holder are capable of holding the first tube connector and the second tube connector in a posture in which the sealing bodies of each of the first tube connector and the second tube connector face each other. ,
The heating means is capable of heating the sealing body of each of the first tube connector and the second tube connector,
The tube connection system, wherein the pulling means is capable of pulling out the sealing bodies of each of the first tube connector and the second tube connector in a second direction perpendicular to the first direction.
The tube connection system according to claim 1, further comprising the first tube connector and the second tube connector.
The moving means includes a first position in which the sealing bodies of the first tube connector and the second tube connector are arranged facing each other and separated from each other; a second position in which the sealing bodies are brought into contact with each other, and a third position in which the flange portions of the first tube connector and the second tube connector are brought into pressure contact with each other,
The heating means heats the sealing body of each of the first tube connector and the second tube connector when in the second position,
The tube connection according to claim 2, wherein the pulling means pulls out the heated sealing bodies of each of the first tube connector and the second tube connector in the second direction when in the second position. system.
The flange portion has an annular first end face facing the other side in the first direction, and a flange recess that is recessed from the first end face toward one side in the first direction on the radially inner side of the first end face. death,
3. The tube connection system of claim 2, wherein the flange recess surrounds the internal flow path when viewed in the first direction.
Each of the first tube connector and the second tube connector includes an annular elastic body that is attached to the flange recess and has a higher temperature limit than the first end surface,
The annular elastic body has a first through hole communicating with the internal flow path, and a second through hole that is located on the other side in the first direction than the first end surface in a natural state and faces the other side in the first direction. having an end surface;
The tube connection system according to claim 4, wherein the sealing body covers the first end surface and the second end surface.
Each of the first tube connector and the second tube connector includes an annular body that is attached to the flange recess and has a higher temperature limit than the first end surface,
The annular body has a second through hole communicating with the internal flow path, and a third end face facing the other side in the first direction,
The tube connection system according to claim 4, wherein the sealing body covers the first end surface and the third end surface.
Each of the first holder and the second holder has a first fitting shape,
each of the first tube connector and the second tube connector has a second fitting shape;
The tube connection system according to claim 2, wherein the first fitting shape and the second fitting shape can be fitted in a positioned state.
The tube connection system according to claim 2, further comprising a sealing body collecting section for recovering the sealing body pulled out by the pulling means.
The tube connection system according to claim 2, wherein the sealing body includes a thin metal plate or a thin metal film.
The sealing body has a first portion that overlaps the flange portion when viewed in the first direction, and a second portion that extends from the first portion in a direction perpendicular to the first direction. 2. The tube connection system according to 2.
The tube connection system according to claim 10, wherein a non-slip structure is provided on a first surface of the second portion facing one side in the first direction.
A tube connector set constituting the tube connection system according to any one of claims 2 to 11,
A tube connector set including the first tube connector and the second tube connector.