WO2023227924A1 - Producing microencapsulated powder of natural essence of herbals with retained active components, scent, flavor, and medicinal properties and extended shelf life - Google Patents

Producing microencapsulated powder of natural essence of herbals with retained active components, scent, flavor, and medicinal properties and extended shelf life Download PDF

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Publication number
WO2023227924A1
WO2023227924A1 PCT/IB2022/054915 IB2022054915W WO2023227924A1 WO 2023227924 A1 WO2023227924 A1 WO 2023227924A1 IB 2022054915 W IB2022054915 W IB 2022054915W WO 2023227924 A1 WO2023227924 A1 WO 2023227924A1
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Prior art keywords
essence
flavor
water
scent
powder
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PCT/IB2022/054915
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French (fr)
Inventor
Sadaf JAZAYERI
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Jazayeri Sadaf
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Priority to PCT/IB2022/054915 priority Critical patent/WO2023227924A1/en
Publication of WO2023227924A1 publication Critical patent/WO2023227924A1/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00—Shaping or working of foodstuffs characterised by the products
    • A23P10/30—Encapsulation of particles, e.g. foodstuff additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00—Shaping or working of foodstuffs characterised by the products
    • A23P10/40—Shaping or working of foodstuffs characterised by the products free-flowing powder or instant powder, i.e. powder which is reconstituted rapidly when liquid is added
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds

Definitions

  • Plant extracts Plant extracts, their artificial duplicates, or their derivatives (A23L 33/105)
  • the invention relates to microcapsules, and a continuous micro-encapsulation water-in-oil-in-water microencapsulation process through in situ and interfacial polymerization of the emulsion.
  • the formulation comprises a continuous water phase having a dispersion of microcapsules which contain oil drops and wherein the inside of each oil phase drop—containing optionally oil-soluble materials—there is a dispersion of water, or aqueous extract or water-dispersible material or water-soluble material.
  • the oil drops are encapsulated with a polymer able material of natural origin.
  • Such microcapsules are appropriated for spray-dry processes, to be used as a dry powder, lyophilized, self-emulsifiable powder, gel, cream, and any liquid form.
  • the active compounds included in the microcapsules are beneficial to health and other biological purposes.
  • Such formulations are appropriate to be incorporated in any class of food, especially for the production of nutraceuticals, as well as cosmetic products (such as rejuvenescence creams, anti-wrinkle creams, gels, bath and shower consumable products, and sprays).
  • the preparations are adequate to stabilize compounds added to the food, media for cultivating microbes, and nutraceuticals, especially those which are easily degradable or oxidizable.
  • this patent only the microencapsulation process is described, which is used to produce different products. However, in my plan, this process is explained to produce a beverage powder that can be easily made and consumed.
  • Milk-derived whey protein-based microencapsulating agents and a method for microencapsulation of volatile or non-volatile core materials are used for microencapsulation of active ingredients cores.
  • Whey proteins microencapsulated cores are easy to handle and store, have higher stability, protect the encapsulated core from deteriorating factors, prevent evaporation of volatile cores, transform liquid cores into free-flowing powders, and provide greater versatility of microencapsulated products.
  • Methods for fortifying a beverage with one or more citrus phytochemicals while concealing the bitter taste of these compounds in the beverage. These methods comprise microencapsulating the citrus phytochemicals and adding the microencapsulated citrus phytochemicals to beverages. Also disclosed are beverages fortified with one or more microencapsulated citrus phytochemicals but which do not have the bitter taste characteristics of these compounds.
  • a poultry feed additive composition which is a flowable mixture of phytogenic compounds including at least an oil component which is microencapsulated essential thyme oil, and a saponin component which is the saponin contained in particulate dried quillaja bark powder.
  • the mixture contains at least 0.5% saponin component (w/w), and the oil component in an effective ratio of at least 0.2:1 (w/w, oil component per saponin component), for improving the feed conversion efficiency in antibiotic-free poultry production.
  • the present invention describes the encapsulation of water-insoluble oils by concertation and the subsequent reduction in oxidative degradation of these oils in microencapsulated forms.
  • Water-insoluble oils useful in the process of the invention include food oils such as PUFA, flavor oils, and agriculturally and pharmaceutically active oils.
  • NGF microencapsulation compositions having controlled release characteristics, preferably with increased stability, for the NGF component, particularly human recombinant NGF (“rhNGF”) are provided that yield enhanced stability of NGF for use in promoting nerve cell growth, repair, survival, differentiation, maturation or function. Methods for making and using such compositions are also provided.
  • NGF component particularly human recombinant NGF (“rhNGF”)
  • rhNGF human recombinant NGF
  • Hemp seed protein fractions are provided with particular applicability for forming stable emulsions for microencapsulating lipid-based components.
  • the hemp seed protein fraction is extracted from a hemp seed protein source by aqueous alkaline extraction, followed by separation to provide an aqueous hemp protein solution and residual hemp protein source solids.
  • the hemp seed protein fraction is isolated from the aqueous hemp protein solution by either i) precipitating hemp proteins from the separated aqueous hemp protein solution at or above the isoelectric pH and at a temperature no greater than 70° C., and separating the precipitated proteins to produce a hemp seed protein fraction, or ii) ultra-filtering the separated aqueous hemp protein solution to produce a hemp seed protein fraction having a molecular weight of 5,000 Da and higher.
  • the isolated hemp seed protein fractions form stable emulsions with lipid-based components and form microencapsulated powders.
  • the invention discloses a novel moxibustion patch which comprises a base layer, and a heat source layer, a Chinese herbal medicine essential oil layer, a Chinese herbal medicine powder layer, a moxa layer and an essential oil guide layer which are sequentially arranged on the base layer, wherein medicine powder in the Chinese herbal medicine powder layer and medicine essential oil in the Chinese herbal medicine essential oil layer are prepared by the following method of selecting a traditional Chinese medicine formula for symptomatic treatment, respectively taking each raw material according to the formula, classifying each raw material according to oil yielding properties, dividing each raw material into an oil-yielding Chinese herbal medicine and an oil-yielding Chinese herbal medicine, grinding the divided oil-yielding Chinese herbal medicine into powder to obtain medicine powder, extracting medicinal component essential oil from the divided oil-yielding Chinese herbal medicine by adopting a microwave extraction technology, and wrapping the medicine essential oil by adopting ⁇ -cyclodextrin.
  • Aromatic medicinal herbs have been employed in producing drugs and in flavoring foods for a long time;
  • the active ingredients extracted from herbs are categorized into three groups: extract, distillate, and essence.
  • Distillate consists mainly of water, and has only a small amount of active ingredients, scent, and flavor in it;
  • Aromatic medicinal herbs have been known and employed in pharmaceutical and food flavor products for a long time.
  • the active ingredients extracted from herbs are categorized into three groups: extract, distillate, and essence. Each has its distinctive compound, strengths, and weaknesses point.
  • the extracts and extraction process relies on the solubility of the desired substance in the water or oil phase as their solvent. Normally this process involves a thermal treatment to make the operation easier, which results in remarkable harmful effects. On the other hand, complete separation of the solvent is not an easy process. Most importantly, even though the extract is highly concentrated, the end product is very likely to contain the harmful compounds of herbs.
  • essence is produced through distillation. Since essence is low molecular and volatile, they evaporate quickly; thus, they are exposed to less heat in the process and experience lower detrimental impacts, and contain a higher percentage of active ingredients. The little amount of essence that remains in the solvent (usually water) becomes the part of the distillate and produces hydrosol. Meanwhile, the essence would appear in a separate phase of distillate due to its hydrophobic nature. To put it another way, based on the process, the essence is the concentrate of the active ingredients and aromatic components of herbals and plants. Regardless of the nutritious and healthful nature of the essences, they can be oxidized and eventually nullified in the presence of air, light, and heat. Moreover, as essences are in liquid form, they cannot be incorporated as part of the flavoring to dry food ingredients, particularly instant or powdered food products.
  • distillate or hydrosol consists mainly of water, and has only a small amount of active ingredients, scent, and flavor; therefore, transportation and maintenance costs are incurred to preserve water.
  • this invention would concentrate the active ingredients (i.e., medicinal and chemical compounds responsible for aroma and flavor) with high yield while extending their shelf life due to the right selection of encapsulating/carrier material and enhanced solubility
  • Transformation of essence e.g., mint, tarragon, rose, and orange
  • concentration of the aromatic compounds facilitated the way for preparing a drink smelling and tasting like distillates simply by adding a smidgen of the powder into water.
  • This creation is to retain its scent and flavor for more than nine months, and due to its dry nature, this product does not need to be pasteurized and can remain intact for months, as far as decomposition is concerned.
  • the method is not just limited to the tested items, and it can apply to other herbs by tweaking the settings. Confidently, this product will be desired not only by domestic but international consumers due to its fine quality and lower transportation costs contrasted to distillates.
  • This invention is an herbal essence in the form of soluble microencapsulated powder to retain active ingredients, aroma, flavor, and medicinal properties for an extended expiration date.
  • the herbal essence is initially mixed with Maltodextrin and water, then dried and formed into powders by a spray dryer.
  • the parameters of the spray dryer, the amount of essence, water, and Maltodextrin are all optimized.
  • this substance alone will discharge its original scent and flavor, and for this product to be multipurpose, it could be packed along with instant drinks containing for example flixweed s and basil seed accompanied by sugar or rock candy Accordingly, consumers will need to do add the contents into the water to have a sweetened, mint-flavored flixweed drink.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
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  • Alternative & Traditional Medicine (AREA)
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Abstract

It is an herbal essence in the form of soluble microencapsulated powder to retain active ingredients, scent, flavor, and medicinal properties for longer shelf life. To accomplish this invention, the following have been examined: choose extract, essence, or distillate as a suitable raw material, methods/processes of drying which are convection, hot conductor/ air/ surface, optimal parameters of temperature, time, and pressure in the drying process, different ways of preservation which are microencapsulation and Nanoencapsulation, and choose kind of carrier. Due to its dry nature, this product does not need to be pasteurized and can remain intact for months, as far as decomposition is concerned and the selected technique with the capability of re-sizing the particles to a small size would facilitate their solubility in water.

Description

Producing microencapsulated powder of natural essence of herbals with retained active components, scent, flavor, and medicinal properties and extended shelf life
It is an herbal essence in the form of soluble microencapsulated powder to retain active ingredients, scent, flavor, and medicinal properties for longer shelf life. To accomplish this invention, the following have been examined: choose extract, essence, or distillate as a suitable raw material, methods/processes of drying which are convection, hot conductor/ air/ surface, optimal parameters of temperature, time, and pressure in the drying process, different ways of preservation which are microencapsulation and Nanoencapsulation, and choose kind of carrier. Due to its dry nature, this product does not need to be pasteurized and can remain intact for months, as far as decomposition is concerned and the selected technique with the capability of re-sizing the particles to a small size would facilitate their solubility in water.
Plant extracts, their artificial duplicates, or their derivatives (A23L 33/105)
Continuous multi-microencapsulation process for improving the stability and storage life of biologically active ingredients
United States Patent Application 20080102132
The invention relates to microcapsules, and a continuous micro-encapsulation water-in-oil-in-water microencapsulation process through in situ and interfacial polymerization of the emulsion. The formulation comprises a continuous water phase having a dispersion of microcapsules which contain oil drops and wherein the inside of each oil phase drop—containing optionally oil-soluble materials—there is a dispersion of water, or aqueous extract or water-dispersible material or water-soluble material. The oil drops are encapsulated with a polymer able material of natural origin. Such microcapsules are appropriated for spray-dry processes, to be used as a dry powder, lyophilized, self-emulsifiable powder, gel, cream, and any liquid form. The active compounds included in the microcapsules are beneficial to health and other biological purposes.
Such formulations are appropriate to be incorporated in any class of food, especially for the production of nutraceuticals, as well as cosmetic products (such as rejuvenescence creams, anti-wrinkle creams, gels, bath and shower consumable products, and sprays). The preparations are adequate to stabilize compounds added to the food, media for cultivating microbes, and nutraceuticals, especially those which are easily degradable or oxidizable. In this patent, only the microencapsulation process is described, which is used to produce different products. However, in my plan, this process is explained to produce a beverage powder that can be easily made and consumed.
Milk derived whey protein-based microencapsulating agents and a method of use
The United States Patent 5601760
Milk-derived whey protein-based microencapsulating agents and a method for microencapsulation of volatile or non-volatile core materials. Milk-derived whey protein concentrates or whey protein isolate alone or in admixture with other milk or non-milk-derived products are used for microencapsulation of active ingredients cores. Whey proteins microencapsulated cores are easy to handle and store, have higher stability, protect the encapsulated core from deteriorating factors, prevent evaporation of volatile cores, transform liquid cores into free-flowing powders, and provide greater versatility of microencapsulated products.
Microencapsulated citrus phytochemicals and application to beverages
The United States Patent 9545117
Methods are disclosed for fortifying a beverage with one or more citrus phytochemicals while concealing the bitter taste of these compounds in the beverage. These methods comprise microencapsulating the citrus phytochemicals and adding the microencapsulated citrus phytochemicals to beverages. Also disclosed are beverages fortified with one or more microencapsulated citrus phytochemicals but which do not have the bitter taste characteristics of these compounds.
Poultry feed additive
The United States Patent 10688145
The use of a poultry feed additive composition which is a flowable mixture of phytogenic compounds including at least an oil component which is microencapsulated essential thyme oil, and a saponin component which is the saponin contained in particulate dried quillaja bark powder. The mixture contains at least 0.5% saponin component (w/w), and the oil component in an effective ratio of at least 0.2:1 (w/w, oil component per saponin component), for improving the feed conversion efficiency in antibiotic-free poultry production.
Encapsulation of oils by a concertation
United States Patent Application 20090189304
The present invention describes the encapsulation of water-insoluble oils by concertation and the subsequent reduction in oxidative degradation of these oils in microencapsulated forms. Water-insoluble oils useful in the process of the invention include food oils such as PUFA, flavor oils, and agriculturally and pharmaceutically active oils.
Controlled release microencapsulated NGF formulation
The United States Patent 6113947
NGF microencapsulation compositions having controlled release characteristics, preferably with increased stability, for the NGF component, particularly human recombinant NGF ("rhNGF") are provided that yield enhanced stability of NGF for use in promoting nerve cell growth, repair, survival, differentiation, maturation or function. Methods for making and using such compositions are also provided.
Hemp Protein and Use for Microencapsulation
United States Patent Application 20190335800
Hemp seed protein fractions are provided with particular applicability for forming stable emulsions for microencapsulating lipid-based components. The hemp seed protein fraction is extracted from a hemp seed protein source by aqueous alkaline extraction, followed by separation to provide an aqueous hemp protein solution and residual hemp protein source solids. The hemp seed protein fraction is isolated from the aqueous hemp protein solution by either i) precipitating hemp proteins from the separated aqueous hemp protein solution at or above the isoelectric pH and at a temperature no greater than 70° C., and separating the precipitated proteins to produce a hemp seed protein fraction, or ii) ultra-filtering the separated aqueous hemp protein solution to produce a hemp seed protein fraction having a molecular weight of 5,000 Da and higher. The isolated hemp seed protein fractions form stable emulsions with lipid-based components and form microencapsulated powders.
Moxibustion patch and moxibustion patch combination
The invention discloses a novel moxibustion patch which comprises a base layer, and a heat source layer, a Chinese herbal medicine essential oil layer, a Chinese herbal medicine powder layer, a moxa layer and an essential oil guide layer which are sequentially arranged on the base layer, wherein medicine powder in the Chinese herbal medicine powder layer and medicine essential oil in the Chinese herbal medicine essential oil layer are prepared by the following method of selecting a traditional Chinese medicine formula for symptomatic treatment, respectively taking each raw material according to the formula, classifying each raw material according to oil yielding properties, dividing each raw material into an oil-yielding Chinese herbal medicine and an oil-yielding Chinese herbal medicine, grinding the divided oil-yielding Chinese herbal medicine into powder to obtain medicine powder, extracting medicinal component essential oil from the divided oil-yielding Chinese herbal medicine by adopting a microwave extraction technology, and wrapping the medicine essential oil by adopting β -cyclodextrin.
Applications of microencapsulated essential oils
The United States Patent 9717240
Method for the preparation of microencapsulated essential oils or a formulation thereof for various non-agricultural applications.
Aromatic medicinal herbs have been employed in producing drugs and in flavoring foods for a long time; The active ingredients extracted from herbs are categorized into three groups: extract, distillate, and essence. Distillate consists mainly of water, and has only a small amount of active ingredients, scent, and flavor in it; We intend to invent a natural product in the form of encapsulated micronized powder from herbs to retain active ingredients for an extended shelf life regardless of in which season it may be used.
To accomplish this invention, the following have been examined:
  • Whether to choose extract, essence, or distillate as an appropriate raw material,
  • The methods/processes of drying which are convection, hot conductor/ air/ surface,
  • The optimal parameters of temperature, time, and pressure in the drying process,
  • The different ways of preservation which are microencapsulation and Nanoencapsulation, and
  • What kind of carrier to choose?
Aromatic medicinal herbs have been known and employed in pharmaceutical and food flavor products for a long time. The active ingredients extracted from herbs are categorized into three groups: extract, distillate, and essence. Each has its distinctive compound, strengths, and weaknesses point.
The extracts and extraction process relies on the solubility of the desired substance in the water or oil phase as their solvent. Normally this process involves a thermal treatment to make the operation easier, which results in remarkable harmful effects. On the other hand, complete separation of the solvent is not an easy process. Most importantly, even though the extract is highly concentrated, the end product is very likely to contain the harmful compounds of herbs.
By contrast, the essence is produced through distillation. Since essence is low molecular and volatile, they evaporate quickly; thus, they are exposed to less heat in the process and experience lower detrimental impacts, and contain a higher percentage of active ingredients. The little amount of essence that remains in the solvent (usually water) becomes the part of the distillate and produces hydrosol. Meanwhile, the essence would appear in a separate phase of distillate due to its hydrophobic nature. To put it another way, based on the process, the essence is the concentrate of the active ingredients and aromatic components of herbals and plants. Regardless of the nutritious and healthful nature of the essences, they can be oxidized and eventually nullified in the presence of air, light, and heat. Moreover, as essences are in liquid form, they cannot be incorporated as part of the flavoring to dry food ingredients, particularly instant or powdered food products.
Comparatively, distillate or hydrosol consists mainly of water, and has only a small amount of active ingredients, scent, and flavor; therefore, transportation and maintenance costs are incurred to preserve water.
On the other hand, regarding the seasonality of herbs growth, producers have to manufacture colossal amounts of essence and distillate within a short period, in which case quite a few warehouses are required to facilitate sales through the year; however, the products may be vulnerable to degradation. In addition, manufacturers will be faced with the considerably high cost of export for a product that is composed of over 90% of water.
We intend to invent natural herbal-based products in the form of encapsulated micronized powder which retains concentrated active ingredients, scent, flavor, and medicinal properties with an extended shelf life. The product of this invention must dissolve easily in cold water, without showing phase separation due to its essential oil nature. This powdered microcapsule of essential oils would have the potential to re-hydrate and create a distillate product for a uniform steady drink with the desired scent, flavor, and medicinal properties.
To accomplish this invention, the following have been examined:
Whether to choose extract, essence, or distillate as a suitable raw material,
The methods/processes of drying which are convection or conduction (hot air or surface)
The optimal parameters of temperature, time, and pressure in the drying process,
The different ways of preservation/coating which are micro and Nanoencapsulation, and
What kind of carrier to choose?
Solution of problem
Not only nations surrounding the Persian Gulf but also European and Northern American countries have a preference for foods and drinks made basically from healthful, aromatic natural vegetation rather than synthetic materials. Distillates and essences, which encompass the favorable properties mentioned, must be able to be used effortlessly and be as available and economic as possible to consumers. Nonetheless, seasonality of the production, transportation, and warehousing costs, the fact that the amount of the active ingredients tend to vary in the production process and cannot be controlled, and degradation of the product in terms of its active ingredients, scent, and flavor are obstacles to consuming distillates both domestically and internationally.
Hence, the deployment of an advanced method of drying without adverse effect on active components would concentrate them and the final product have the potential to rehydrate and produce distillate or hydrosol with condensed active components. Concerning that volatile compounds of distillates or essential oils are not safeguarded, in this invention encapsulation is performed during the drying process, which protects the ingredients from the heat generated by dryers and is also a barrier against any kind of products exposure to the environment. It should be noted that the selected technique with the capability of re-sizing the particles to a small size would facilitate their solubility in water.
With the selection of the right high-tech drying technique, this invention would concentrate the active ingredients (i.e., medicinal and chemical compounds responsible for aroma and flavor) with high yield while extending their shelf life due to the right selection of encapsulating/carrier material and enhanced solubility
Dissolved in cold water, only a small amount of this powder can produce an aromatic, transparent drink with remedial properties corresponding to distillates. The end product is remarkably soluble in cold water, which is one of the evaluation indicators.
No emulsifiers or other additives are used in the encapsulation and production of essences. The end product is a great deal more compact than the primary product, which leads to lower transportation costs. Considering the vulnerability and hydrophobicity of the active ingredients, micronizing the ingredients and providing them with a protective coating can significantly protect them from any undesirable effects. Additionally, this invention can be extensively used in the formulation of various products; e.g., instant drinks, as opposed to distillates with their limited usage in flavoring and scenting certain foods.
Utilizing the natural essence of herbs (after examination, we discovered that a small amount of essence can create a superior aroma and flavor than distillate) and employing a spray dryer with the optimal temperature, time, and speed can cause less damage to the active ingredients compared to other drying processes. The employment of the selection of the right Maltodextrin (with correct dextrose equivalent number) is also another subject we have taken into account, as it is highly soluble and can produce a transparent drink.
Transformation of essence (e.g., mint, tarragon, rose, and orange) into powder is conducted most meticulously and cautiously in the laboratory so as not to damage the active ingredients. The concentration of the aromatic compounds facilitated the way for preparing a drink smelling and tasting like distillates simply by adding a smidgen of the powder into water. This creation is to retain its scent and flavor for more than nine months, and due to its dry nature, this product does not need to be pasteurized and can remain intact for months, as far as decomposition is concerned. It is worth mentioning, the method is not just limited to the tested items, and it can apply to other herbs by tweaking the settings. Confidently, this product will be desired not only by domestic but international consumers due to its fine quality and lower transportation costs contrasted to distillates.
This invention is an herbal essence in the form of soluble microencapsulated powder to retain active ingredients, aroma, flavor, and medicinal properties for an extended expiration date. According to the proposal, the herbal essence is initially mixed with Maltodextrin and water, then dried and formed into powders by a spray dryer. The parameters of the spray dryer, the amount of essence, water, and Maltodextrin are all optimized. Added to water, this substance alone will discharge its original scent and flavor, and for this product to be multipurpose, it could be packed along with instant drinks containing for example flixweed s and basil seed accompanied by sugar or rock candy Accordingly, consumers will need to do add the contents into the water to have a sweetened, mint-flavored flixweed drink.
Instructions on how to produce this herbal powder are mentioned below:
To begin with, we blend the following items:
Twenty grams of Maltodextrin with a dextrose equivalent over 18 (the higher the DE value, the more the solubility),
One gram of essence (mint essence or other essences) which is derived from the distillation process, and
Seventy-nine grams of water purified by reverse osmosis.
Then, we add them into a mixer. Next, we feed this mixture into the spray dryer and run the instrument (the inlet and outlet temperature of this dryer are 120°C and 60°C respectively, and the pump is set at 13%). Eventually, the product is discharged from the spray dryer as powders and is ready to be packed.
It is worth noting that the number of raw materials, temperature, and processing speed are all optimized in a way that the particles can disperse in water and stay homogeneous to a great extent with no emulsifier needed.
Advantage effects of invention
Preservation of high amounts of natural active ingredients (aroma carriers and medicinal properties) in the final product
Performing two processes of drying and coating effective compounds without the need for further processes for microbial detoxification, etc.
Microencapsulation of effective compounds that increase the shelf life, which ultimately preserves the flavor and medicinal properties
The high solubility of essential oil capsules encapsulated in cold water
Use of minimum additives to solubilize effective oily compounds in an aqueous medium and prevent two-phase in the aqueous phase
High fissure after dissolution in water
Ability to produce in the relevant plant growing season and use throughout the year
Reduce storage space and related costs
Natural and authorized product for consumption in the field of food and pharmaceutical industries
: block diagram of producing microencapsulated powder of natural essence of herbals with retained active components.
: block diagram of producing microencapsulated powder of natural essence of herbals with retained active components.
Examples
By using this design in the form of a powder of natural plant essential oils, which can be easily transported for export and can be used in all seasons. How to use and combine it in the aqueous phase is as follows: Mix water, Maltodextrin, and peppermint essential oil and pour it into the spray dryer, then it comes out of the spray dry as a powder. For multi-purpose use, this product is packaged in packages containing sorrel or syrup eggs with sugar or candy and can be provided as an instant drink in single-person packages for home consumption. It is enough for the consumer to pour the relevant package in water and prepare a syrup containing sweetened ash with mint flavor or any other essential oil.
Launching a mass production line of encapsulated powder of all kinds of natural essential oils for use in the fields of medicine, food, and cosmetics. This powder can also be used as an instant beverage alone or in combination with other ingredients in homes, food factories, offices, parties, travel transportation industries.

Claims (7)

  1. This invention is an herbal essence in the form of soluble microencapsulated powder to retain active ingredients, scent, flavor, and medicinal properties for longer shelf life.
    To accomplish this invention, the following have been examined:
    Whether to choose extract, essence, or distillate as a suitable raw material,
    The methods/processes of drying which are convection, hot conductor/ air/ surface,
    The optimal parameters of temperature, time, and pressure in the drying process,
    The different ways of preservation which are microencapsulation and Nanoencapsulation, and
    What kind of carrier to choose?
    The method is not just limited to the tested items, and it can apply to other herbs by tweaking the settings.
  2. According to claim 1, to produce this powder, we blend the following items:
    Twenty grams of Maltodextrin with a dextrose equivalent over 18 (the higher the DE value, the more the solubility),
    One gram of essence (mint essence or other essences) which is derived from the distillation process, and
    Seventy-nine grams of water purified by reverse osmosis.
    Then, we add them into a mixer.
  3. According to claim 2, we feed this mixture into the spray dryer and run the machine (the inlet and outlet temperature of this dryer are 120°C and 60°C respectively, and the pump is set at 13%). Eventually, the product is discharged from the spray dryer as powders and is ready to be packed.
  4. According to claim 3, the number of raw materials, temperature, and processing speed are all optimized in a way that the particles can disperse in water and stay homogeneous to a great extent with no emulsifier needed.
  5. Considering the vulnerability and hydrophobicity of the active ingredients, micronizing the ingredients and providing them with a protective coating can significantly protect them from any undesirable effects. Additionally, this invention can be extensively used in the formulation of various products; e.g., instant drinks.
  6. Due to its dry nature, this product does not need to be pasteurized and can remain intact for months, as far as decomposition is concerned.
  7. The selected technique with the capability of re-sizing the particles to a small size would facilitate their solubility in water.
PCT/IB2022/054915 2022-05-25 2022-05-25 Producing microencapsulated powder of natural essence of herbals with retained active components, scent, flavor, and medicinal properties and extended shelf life WO2023227924A1 (en)

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Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ADAMIEC JANUSZ, KALEMBA DANUTA: "Analysis of Microencapsulation Ability of Essential Oils during Spray Drying", DRYING TECHNOLOGY., TAYLOR & FRANCIS, PHILADELPHIA, PA., US, vol. 24, no. 9, 1 September 2006 (2006-09-01), US , pages 1127 - 1132, XP093115057, ISSN: 0737-3937, DOI: 10.1080/07373930600778288 *
ALAşALVAR HAMZA; ÇAM MUSTAFA: "Ready to drink iced teas from microencapsulated spearmint (L.) and peppermint (L.) extracts: physicochemical, bioactive and sensory characterization", JOURNAL OF FOOD MEASUREMENT AND CHARACTERIZATION, SPRINGER US, BOSTON, vol. 14, no. 3, 17 February 2020 (2020-02-17), Boston , pages 1366 - 1375, XP037109228, ISSN: 2193-4126, DOI: 10.1007/s11694-020-00386-4 *

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