WO2023227874A1

WO2023227874A1 - An agrochemical concentrate composition

Info

Publication number: WO2023227874A1
Application number: PCT/GB2023/051344
Authority: WO
Inventors: Pradip WAGH; Rohit Patil; Robert Burton; Charles FLOOD
Original assignee: Upl Mauritius Limited; Upl Europe Ltd
Priority date: 2022-05-23
Filing date: 2023-05-23
Publication date: 2023-11-30
Also published as: GB202207511D0

Abstract

The present disclosure relates to an agrochemical concentrate composition comprising a neonicotinoid insecticide and a diamide insecticide. The present disclosure also relates to a process for preparing the agrochemical concentrate composition and a method for controlling growth of insects/pests using the same.

Description

TITLE: AN AGROCHEMICAL CONCENTRATE COMPOSITION

FIELD OF THE DISCLOSURE:

The present disclosure relates to an agrochemical concentrate composition, and in particular to an insecticidal concentrate composition.

BACKGROUND OF THE DISCLOSURE:

In the agrochemical applications, liquid concentrate compositions are sometimes preferred over other types of formulations due to ease of making and using. Concentrated compositions have grown in popularity due to various benefits such as being free from dust that may cause health hazard to people exposed during manufacturing as well as at the end user level. They can be conveniently diluted to bigger volumes during application without involving sophisticated machinery before final use.

Concentrated compositions such as suspension concentrate (SC) and flowable concentrate for seed treatment (FS) are dispersions of an insoluble solid into a liquid media. The liquid media can be water or any organic/inorganic solvent. Problem arises when slightly water-soluble ingredients are to be formulated as a concentrate. A major drawback of formulating a slightly water-soluble ingredient in water-based concentrate compositions is Ostwald ripening, which refers to instances in which larger crystals of the ingredient grow while the smaller crystals dissolve. Physical instability is one manifestation of Ostwald ripening. Further effects of Ostwald ripening include limited utility of the formulation because an acceptable shelf-life may not be obtained. For instance, a two-year shelf-life is typically needed for a successful commercial product in agrochemicals. Also, crystals that grow too large may plug spray equipment and may not stay suspended in the spray tank or concentrated formulation. Acetamiprid is chemically known as N-(N-cyano group-ethyleneimine base)-N- methyl-2-chloropyridine-5-methylamine. Acetamiprid is a high-efficiency neonicotinoid insecticide that has good control on variety of agricultural pests. Acetamiprid acts by affecting the synapses in the insect central nervous system. It is a systemic insecticide with translaminar activity and with contact and stomach action. It has been widely used for control of Hemiptera, especially aphids, Thysanoptera and Lepidoptera, by soil and foliar application, on a wide range of crops, especially vegetables, fruits and tea.

Compositions containing combinations of two or more insecticides have been known in the art, but problems such as the physical instability of such mixtures during manufacture, shelf life or dilution at the time of application can adversely impact the efficacy associated with the insecticide combination.

Compositions of neonicotinoid insecticides, especially acetamiprid when formulated in the liquid concentrate form exhibits stability problems related to rapid crystal formation as it is slightly soluble in water. When concentrate composition is made, instability appears due to gelling, caking and settling due to aggregation of particles of acetamiprid. This leads to crystal growth in the composition. The problem further aggravates when at least one additional active ingredient is combined with acetamiprid. The interaction at molecular level facilitated by a liquid medium brings upon morphological changes, which further contributes to the instability of the overall composition.

Selection of appropriate excipients constituting the concentrate composition plays a critical role towards stability of the composition. Hence, there is a need to develop stable agrochemical concentrate composition of acetamiprid in combination with at least one additional active ingredient, wherein the composition does not undergo crystal formation of the active in the medium and remains stable throughout the shelf life as well as during application when it is diluted with water. OBJECTIVES OF THE DISCLOSURE:

An objective of the present disclosure is to provide a stable agrochemical concentrate composition.

Another objective of the present disclosure is to provide a stable agrochemical concentrate composition of a neonicotinoid insecticide.

Another objective of the present disclosure is to provide a stable agrochemical concentrate composition of a neonicotinoid insecticide in combination with at least one additional insecticide.

Another object of the present disclosure is to provide a stable agrochemical concentrate composition of a neonicotinoid insecticide in combination with at least one additional insecticide, which prevents crystal growth in the composition upon storage.

Still another object of the present disclosure is to provide a process of preparing a stable agrochemical concentrate composition of a neonicotinoid insecticide in combination with at least one additional insecticide.

Yet another object of the present disclosure is to provide a method of controlling pests using the stable agrochemical concentrate composition of a neonicotinoid insecticide in combination with at least one additional insecticide.

SUMMARY OF THE DISCLOSURE:

In an aspect of the present disclosure, an agrochemical concentrate composition comprises a neonicotinoid insecticide; a diamide insecticide; at least one polyhydric solvent in an amount from about 0.1% w/w to about 10% w/w of total weight of the composition; and at least one C1-C4 polyalkylene oxide block copolymer. In another aspect of the present disclosure, the agrochemical concentrate composition comprises a neonicotinoid insecticide; a diamide insecticide; at least one polyhydric solvent in an amount from about 0.1% w/w to about 10% w/w of total weight of the composition; and at least one C1-C4 polyalkylene oxide block copolymer; wherein the neonicotinoid insecticide and the diamide insecticide are in a weight ratio from about 2: 1 to about 1 : 1.

In another aspect of the present disclosure, the agrochemical concentrate composition comprises acetamiprid; chlorantraniliprole; at least one polyhydric solvent in an amount from about 0.1% w/w to about 10% w/w of total weight of the composition; and at least one C1-C4 polyalkylene oxide block copolymer; wherein acetamiprid and chlorantraniliprole are in a weight ratio from about 2: 1 to about 1: 1.

In yet another aspect of the present disclosure, a method of controlling insects comprises applying to the insects or their locus thereof, an insectici dally effective amount of an agrochemical concentrate composition comprising a neonicotinoid insecticide; a diamide insecticide; at least one polyhydric solvent in an amount from about 0.1% w/w to about 10% w/w of total weight of the composition; and at least one C1-C4 polyalkylene oxide block copolymer; wherein the neonicotinoid insecticide and the diamide insecticide are in weight ratio from about 2: 1 to about 1: 1.

Additional features and advantages of the present disclosure will be apparent from the detailed description that follows, which illustrates by way of example, the most preferred features of the present disclosure which are not to be construed as limiting the scope of the disclosure described herein.

DETAILED DESCRIPTION OF THE DISCLOSURE:

The present disclosure will now be described hereinafter with reference to the accompanying examples, in which embodiments of the disclosure are shown. This description is not intended to be a detailed catalogue of all the different ways in which the disclosure may be implemented, or all the features that may be added to the instant disclosure. For example, features illustrated with respect to one embodiment may be incorporated into other embodiments, and features illustrated with respect to a particular embodiment may be deleted from that embodiment. Thus, the disclosure contemplates that in some embodiments of the disclosure, any feature or combination of features set forth herein can be excluded or omitted. In addition, numerous variations and additions to the various embodiments suggested herein will be apparent to those skilled in the art in light of the instant disclosure, which do not depart from the instant disclosure. Hence, the following descriptions are intended to illustrate some particular embodiments of the disclosure, and not to exhaustively specify all permutations, combinations and variations thereof.

Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this disclosure belongs. Although methods and materials similar or equivalent to those described herein can be used in the practice or testing of the disclosure, suitable methods and materials are described herein.

It must be noted that, as used in this specification, the singular forms “a”, “an”, and “the” include plural referents unless the content clearly dictates otherwise. The terms “preferred” and “preferably” refer to embodiments of the disclosure that may afford certain benefits, under certain circumstances.

As used herein, the terms “comprising”, “including”, “having”, “containing”, “involving” and the like are to be understood to be open-ended i.e., to mean including but not limited to.

As used herein, the terms “about” or “approximately” are inclusive of the stated value and means within an acceptable range of deviation for the particular value as determined by one of ordinary skill in the art, considering the measurement in question and the error associated with measurement of the particular quantity (i.e., the limitations of the measurement system). For example, “about” can mean within one or more standard deviations, or within ±10% or ±5% of the stated value.

Recitation of ranges of values are merely intended to serve as a shorthand method of referring individually to each separate value falling within the range, unless otherwise indicated herein, and each separate value is incorporated into the specification as if it were individually recited herein. The endpoints of all ranges are included within the range and independently combinable. As used herein, all numerical values or numerical ranges include integers within such ranges and fractions of the values or the integers within ranges unless the context clearly indicates otherwise. Thus, for example, reference to a range of 90-100%, includes 91%, 92%, 93%, 94%, 95%, 95%, 97%, etc., as well as 91.1%, 91.2%, 91.3%, 91.4%, 91.5%, etc., 92.1%, 92.2%, 92.3%, 92.4%, 92.5%, etc., and so forth. All methods described herein can be performed in a suitable order unless otherwise indicated herein or otherwise clearly contradicted by context.

The use of any and all examples, or exemplary language (e.g., “such as”), is intended merely to better illustrate the disclosure and does not pose a limitation on the scope of the disclosure unless otherwise claimed. No language in the specification should be construed as indicating any non-claimed element as essential to the practice of the disclosure as used herein.

While the disclosure has been described with reference to an exemplary embodiment, it will be understood by those skilled in the art that various changes may be made, and equivalents may be substituted for elements thereof without departing from the scope of the disclosure. In addition, many modifications may be made to adapt a particular situation or material to the teachings of the disclosure without departing from the essential scope thereof. Therefore, it is intended that the disclosure is not limited to the particular embodiment disclosed as the best mode contemplated for carrying out this disclosure, but that the disclosure will include all embodiments falling within the scope of the appended claims.

The expression of various quantities in terms of “%” or “% w/v” or “% w/w” means the percentage by weight of the total solution or composition unless otherwise specified.

As used herein, the term “agrochemical” is understood to denote an agricultural chemical such as pesticides, fungicides, insecticides, acaricides, herbicides, nematicides, plant growth regulators and can be used interchangeably.

As used herein, the term “insecticide” refers to the ability of a substance to decrease or inhibit growth of insects or pests.

As used herein, the term “insecticidal” refers to the ability of a substance to control or modify the growth of insects or pests. Insecticidal refers to the ability of a substance to increase mortality and/or inhibit the growth rate of insects or pests.

The term “insecticidally effective amount” means the amount of the composition needed to achieve an observable adverse effect on growth, including the effects of necrosis, death, retardation, prevention, and removal, destruction, insect pest mortality, insect pest weight loss, insect pest reduced plant defoliation, and other behavioural and physical changes of an insect pest after feeding and exposure for an appropriate length of time.

The term “insects” includes all organisms in the class "Insecta”.

The term “control” or “controlling” insects refers to inhibition of insects, through a toxic effect, the ability of insect pests to survive, grow, feed, and/or reproduce, or to limit insect-related damage or loss in crop plants. To “control” insects may or may not mean killing the insects, although it preferably means reducing insect population by killing the insects.

The term “plant” refers to all physical parts of a plant, including seeds, seedlings, saplings, roots, tubers, stems, stalks, foliage and fruits. The term plant includes transgenic and non-transgenic plants.

The term “locus” of a plant as used herein is intended to embrace the place on which the plants are growing, where the plant propagation materials of the plants are sown or where the plant propagation materials of the plants will be placed into the soil.

The term “plant propagation material” is understood to denote generative parts of a plant, such as seeds, vegetative material such as cuttings or tubers, roots, fruits, tubers, bulbs, rhizomes and parts of plants, germinated plants and young plants which are to be transplanted after germination or after emergence from the soil.

The term “seed” as used herein means any resting stage of a plant that is physically detached from the vegetative stage of a plant.

The term “stable” referred to herein refers to chemical and/or physical stabilization of the composition in terms of achieving chemical stability of the active ingredient and desired suspensibility and dispersibility of the composition by maintaining homogeneity of the components that imparts better shelf life.

The inventors of the present disclosure faced challenge of handling crystal growth in concentrated compositions wherein a neonicotinoid insecticide is combined with other active ingredients. It was observed that the presence of two active ingredients, one from neonicotinoid insecticide class and at least one additional active ingredient was found to destabilize the concentrate composition and to cause irreversible crystal growth. The inventors of the present disclosure found that crystal growth in neonicotinoid insecticides based concentrated compositions can be controlled by incorporating at least one polyhydric solvent in an amount from about 0.1% w/w to about 10% w/w of total weight of the composition and at least one C1-C4 polyalkylene oxide block copolymer. If the quantity of the polyhydric solvent increases more than about 10% w/w of total weight of the composition, crystal growth was observed. Similarly, presence of C1-C4 polyalkylene oxide block copolymer was found to be essential in controlling crystal growth in the concentrated composition. Other non-ionic surfactants could not demonstrate crystal growth control. Therefore, inventors found presence of polyhydric solvent and C1-C4 polyalkylene oxide block copolymer essential for stabilizing the composition of the neonicotinoid insecticide.

The present disclosure results into a storage stable agrochemical concentrate composition in which polyhydric solvent is present in an amount from about 0.1% w/w to about 10% w/w of total weight of the composition and presence of at least one C1-C4 polyalkylene oxide block copolymer overcomes crystal growth issues, and the concentrated composition remains stable throughout the shelf life.

Accordingly, the present disclosure provides an agrochemical composition.

In an embodiment, the present disclosure provides an agrochemical concentrate composition.

In an embodiment of the present disclosure, an agrochemical concentrate composition comprises: a neonicotinoid insecticide; a diamide insecticide; at least one polyhydric solvent; and at least one C1-C4 polyalkylene oxide block copolymer.

In an embodiment of the present disclosure, an agrochemical concentrate composition comprises: a neonicotinoid insecticide; a diamide insecticide; at least one polyhydric solvent in an amount from about 0.1% w/w to about 10% w/w of total weight of the composition; and at least one C1-C4 polyalkylene oxide block copolymer.

In an embodiment of the present disclosure, the neonicotinoid insecticide is selected from the group comprising acetamiprid, clothianidin, imidacloprid, nitenpyram, nithiazine, thiacloprid, thiamethoxam, or combinations thereof.

In a preferred embodiment of the present disclosure, the neonicotinoid insecticide is acetamiprid.

In a preferred embodiment of the present disclosure, the neonicotinoid insecticide is imidacloprid.

In a preferred embodiment of the present disclosure, the neonicotinoid insecticide is thiacloprid.

In a preferred embodiment of the present disclosure, the neonicotinoid insecticide is clothianidin.

In an embodiment of the present disclosure, the agrochemical concentrate composition comprises from about 1% w/w to about 60% w/w neonicotinoid insecticide of total weight of the composition.

In an embodiment of the present disclosure, the agrochemical concentrate composition comprises from about 1% w/w to about 50% w/w neonicotinoid insecticide of total weight of the composition. In an embodiment of the present disclosure, the agrochemical concentrate composition comprises from about 1% w/w to about 40% w/w neonicotinoid insecticide of total weight of the composition.

In a preferred embodiment, the agrochemical concentrate composition comprises about 18.18% w/w neonicotinoid insecticide of total weight of the composition.

In a preferred embodiment, the agrochemical concentrate composition comprises about 18.18% w/w acetamiprid of total weight of the composition.

In a preferred embodiment, the agrochemical concentrate composition comprises about 20.40% w/w neonicotinoid insecticide of total weight of the composition.

In a preferred embodiment, the agrochemical concentrate composition comprises about 20.40% w/w acetamiprid of total weight of the composition.

In a preferred embodiment, the agrochemical concentrate composition comprises about 20% w/w acetamiprid of total weight of the composition.

In another preferred embodiment, the agrochemical concentrate composition comprises neonicotinoid insecticide in a concentration of about 200 g/L.

In another preferred embodiment, the agrochemical concentrate composition comprises acetamiprid in a concentration of about 200 g/L.

In an embodiment of the present disclosure, the diamide insecticide is selected from the group comprising chlorantraniliprole (CTPR), cyantraniliprole, tetraniliprole, tetrachlorantraniliprole, or combinations thereof.

In a preferred embodiment of the present disclosure, the diamide insecticide is chlorantraniliprole (CTPR). In a preferred embodiment of the present disclosure, the diamide insecticide is cyantraniliprole.

In an embodiment of the present disclosure, the agrochemical concentrate composition comprises from about 0.1% w/w to about 50% w/w diamide insecticide of total weight of the composition.

In an embodiment of the present disclosure, the agrochemical concentrate composition comprises from about 0.1% w/w to about 40% w/w diamide insecticide of total weight of the composition.

In an embodiment of the present disclosure, the agrochemical concentrate composition comprises from about 0.1% w/w to about 30% w/w diamide insecticide of total weight of the composition.

In a preferred embodiment, the agrochemical concentrate composition comprises about 9.09% w/w diamide insecticide of total weight of the composition.

In a preferred embodiment, the agrochemical concentrate composition comprises about 9.09% w/w chlorantraniliprole of total weight of the composition.

In a preferred embodiment, the agrochemical concentrate composition comprises about 20.60% w/w diamide insecticide of total weight of the composition.

In a preferred embodiment, the agrochemical concentrate composition comprises about 20.60% w/w chlorantraniliprole of total weight of the composition.

In a preferred embodiment, the agrochemical concentrate composition comprises about 20% w/w chlorantraniliprole of total weight of the composition. In a preferred embodiment, the agrochemical concentrate composition comprises about 10% w/w chlorantraniliprole of total weight of the composition.

In another preferred embodiment, the agrochemical concentrate composition comprises diamide insecticide in a concentration of about 100 g/L.

In another preferred embodiment, the agrochemical concentrate composition comprises chlorantraniliprole in a concentration of about 100 g/L.

According to an embodiment of the present disclosure, the agrochemical concentrate composition comprises the neonicotinoid insecticide and the diamide insecticide in a weight ratio from about 2: 1 to about 1 : 1.

In a preferred embodiment, the neonicotinoid insecticide and the diamide insecticide are present in a weight ratio of about 2: 1.

In a preferred embodiment, the neonicotinoid insecticide .and the diamide insecticide are present in a weight ratio of about 1 : 1.

In a preferred embodiment, the neonicotinoid insecticide .and the diamide insecticide are present in a weight ratio of about 0.99: 1.

According to an embodiment of the present disclosure, the agrochemical concentrate composition comprises at least one polyhydric solvent.

According to an embodiment of the present disclosure, the polyhydric solvent is selected from group comprising propylene glycol, glycerin, or combinations thereof.

In a preferred embodiment of the present disclosure, the polyhydric solvent is propylene glycol. In a preferred embodiment of the present disclosure, the polyhydric solvent is glycerin.

In an embodiment of the present disclosure, the agrochemical concentrate composition comprises from about 0.1% w/w to about 10% w/w polyhydric solvent of total weight of the composition.

In an embodiment of the present disclosure, the agrochemical concentrate composition comprises from about 0.5% w/w to about 10% w/w polyhydric solvent of total weight of the composition.

In another embodiment of the present disclosure, the agrochemical concentrate composition comprises from about 1% w/w to about 10% w/w polyhydric solvent of total weight of the composition.

In a preferred embodiment, the agrochemical concentrate composition comprises about 5% w/w polyhydric solvent of total weight of the composition.

In a preferred embodiment, the agrochemical concentrate composition comprises about 5% w/w propylene glycol of total weight of the composition.

In a preferred embodiment, the agrochemical concentrate composition comprises about 10% w/w polyhydric solvent of total weight of the composition.

In a preferred embodiment, the agrochemical concentrate composition comprises about 10% w/w glycerin of total weight of the composition.

According to a preferred embodiment of the present invention, the agrochemical concentrate composition comprises at least one polyhydric solvent in an amount of about 10% of total weight of the composition. According to another embodiment of the present invention, the agrochemical concentrate composition comprises at least one polyhydric solvent in an amount less than about 10% of total weight of the composition.

According to a preferred embodiment of the present invention, the agrochemical concentrate composition comprises at least one polyhydric solvent in an amount less than about 7% of total weight of the composition.

According to a preferred embodiment of the present invention, the agrochemical concentrate composition comprises at least one polyhydric solvent in an amount of about 5% of total weight of the composition.

According to an embodiment of the present disclosure, the agrochemical concentrate composition comprises at least one C1-C4 polyalkylene oxide block copolymer.

According to an embodiment of the present disclosure, the C1-C4 polyalkylene oxide block copolymer is selected from the group comprising Ci polyalkylene oxide block copolymer, C2 polyalkylene oxide block copolymer, C3 polyalkylene oxide block copolymer, C4 polyalkylene oxide block copolymer, or combinations thereof.

According to an embodiment of the present disclosure, the agrochemical concentrate composition comprises at least one Ci polyalkylene oxide block copolymer.

According to an embodiment of the present disclosure, the agrochemical concentrate composition comprises at least one C2 polyalkylene oxide block copolymer. According to an embodiment of the present disclosure, the agrochemical concentrate composition comprises at least one C3 polyalkylene oxide block copolymer.

According to an embodiment of the present disclosure, the agrochemical concentrate composition comprises at least one C4 polyalkylene oxide block copolymer.

According to an embodiment of the present disclosure, the agrochemical concentrate composition comprises mixtures of C1-C4 polyalkylene oxide block copolymer.

According to an embodiment of the present disclosure, the agrochemical concentrate composition comprises a mixture of Ci and C2 polyalkylene oxide block copolymer.

According to an embodiment of the present disclosure, the agrochemical concentrate composition comprises a mixture of Ci and C3 polyalkylene oxide block copolymer.

According to an embodiment of the present disclosure, the agrochemical concentrate composition comprises a mixture of Ci and C4 polyalkylene oxide block copolymer.

According to an embodiment of the present disclosure, the agrochemical concentrate composition comprises a mixture of C2 and C3 polyalkylene oxide block copolymer.

According to an embodiment of the present disclosure, the agrochemical concentrate composition comprises a mixture of C2 and C4 polyalkylene oxide block copolymer. According to an embodiment of the present disclosure, the agrochemical concentrate composition comprises a mixture of C3 and C4 polyalkylene oxide block copolymer.

According to an embodiment of the present disclosure, the C1-C4 polyalkylene oxide block copolymer is selected from the group comprising 1,2-propylene oxide, butyl block polymer; Oxirane, methyl-, polymer with oxirane, monobutyl ether; polyethylene oxide (PEO)-polypropylene oxide (PPO)-polyethylene oxide (PEO) based copolymer; ethylene oxide (EO) propylene oxide (PO)) block copolymer, ether with ethylene diamine tetrapropanol (4: 1); polyalkylene glycol ether, acrylic copolymer solution; C4 polyalkylene oxide block copolymer; C3 polyalkylene oxide block copolymer; or combinations thereof.

In a preferred embodiment, the C1-C4 polyalkylene oxide block copolymer is oxirane, methyl-, polymer with oxirane, monobutyl ether.

In a preferred embodiment, the C1-C4 polyalkylene oxide block copolymer is EO- PO block copolymer.

In a preferred embodiment, the C1-C4 polyalkylene oxide block copolymer is C4 polyalkylene oxide block copolymer.

In a preferred embodiment, the C1-C4 polyalkylene oxide block copolymer is C3 polyalkylene oxide block copolymer.

In an embodiment of the present disclosure, the agrochemical concentrate composition comprises from about 0.1% w/w to about 10% w/w C1-C4 polyalkylene oxide block copolymer of total weight of the composition. In an embodiment of the present disclosure, the agrochemical concentrate composition comprises from about 0.5% w/w to about 10% w/w C1-C4 polyalkylene oxide block copolymer of total weight of the composition.

In a preferred embodiment of the present disclosure, the agrochemical concentrate composition comprises from about 1% w/w to about 10% w/w C1-C4 polyalkylene oxide block copolymer of total weight of the composition.

In a preferred embodiment, the agrochemical concentrate composition comprises about 0.8% w/w C1-C4 polyalkylene oxide block copolymer of total weight of the composition.

In a preferred embodiment, the agrochemical concentrate composition comprises about 0.8% w/w C4 polyalkylene oxide block copolymer of total weight of the composition.

In a preferred embodiment, the agrochemical concentrate composition comprises about 3% w/w C1-C4 polyalkylene oxide block copolymer of total weight of the composition.

In a preferred embodiment, the agrochemical concentrate composition comprises about 3% w/w C3 polyalkylene oxide block copolymer of total weight of the composition.

According to an embodiment, the agrochemical concentrate composition further comprises a dispersant.

In a preferred embodiment, the dispersant is an acrylic copolymer solution.

According to an embodiment, the agrochemical concentrate composition further comprises an adjuvant. In a preferred embodiment, the adjuvant is a mineral oil.

According to an embodiment, the agrochemical concentrate composition further comprises a structuring agent.

In a preferred embodiment, the structuring agent is selected from xanthan gum, smectite clay, or combinations thereof.

In a preferred embodiment, the structuring agent is xanthan gum.

In a preferred embodiment, the structuring agent is smectite clay.

According to an embodiment, the agrochemical concentrate composition further comprises an anti-freeze agent.

In a preferred embodiment, the anti-freeze agent is propylene glycol.

According to an embodiment, the agrochemical concentrate composition further comprises a biocide.

In a preferred embodiment, the biocide is benzisothiazolinone (BIT) solution.

In a preferred embodiment, the biocide is l,2-benzisothiazolin-3-one.

According to an embodiment, the agrochemical concentrate composition further comprises a surfactant.

In a preferred embodiment, the surfactant is selected from EO-PO block copolymer, sodium lignosulphonate, or combinations thereof. In a preferred embodiment, the surfactant is EO-PO block copolymer.

In a preferred embodiment, the surfactant is sodium lignosulphonate.

According to an embodiment, the agrochemical concentrate composition further comprises a suspending agent.

In a preferred embodiment, the suspending agent is micro-fibrillated cellulose.

According to an embodiment, the agrochemical concentrate composition further comprises an adhesion agent.

In a preferred embodiment, the adhesion agent is hydrotreated light paraffinic distillate (white mineral oil).

According to an embodiment, the agrochemical concentrate composition further comprises a colorant.

In a preferred embodiment, the colorant is organic azo pigment.

According to an embodiment, the agrochemical concentrate composition further comprises a pH-regulating agent.

In a preferred embodiment, the pH-regulating agent is acetic acid.

According to an embodiment, the agrochemical concentrate composition further comprises an antifoaming agent.

In a preferred embodiment, the antifoaming agent is non-ionic aqueous emulsion of polydimethylsiloxane. According to an embodiment of the present disclosure, an agrochemical concentrate composition comprises a neonicotinoid insecticide; a diamide insecticide; at least one polyhydric solvent; and at least one C1-C4 polyalkylene oxide block copolymer; wherein the neonicotinoid insecticide and the diamide insecticide are in a weight ratio from about 2: 1 to about 1 : 1.

According to an embodiment of the present disclosure, an agrochemical concentrate composition comprises a neonicotinoid insecticide; a diamide insecticide; at least one polyhydric solvent in an amount from about 0.1% w/w to about 10% w/w of total weight of the composition; and at least one C1-C4 polyalkylene oxide block copolymer; wherein the neonicotinoid insecticide and the diamide insecticide are in a weight ratio from about 2: 1 to about 1 : 1.

According to an embodiment of the present disclosure, an agrochemical concentrate composition comprises: acetamiprid; chlorantraniliprole; at least one polyhydric solvent; and at least one C1-C4 polyalkylene oxide block copolymer.

According to an embodiment of the present disclosure, an agrochemical concentrate composition comprises: acetamiprid; chlorantraniliprole; at least one polyhydric solvent in an amount from about 0.1% w/w to about 10% w/w of total weight of the composition; and at least one C1-C4 polyalkylene oxide block copolymer.

According to an embodiment of the present disclosure, an agrochemical concentrate composition comprises: acetamiprid and chlorantraniliprole in a weight ratio from about 2: 1 to about 1 : 1; at least one polyhydric solvent in an amount from about 0.1% w/w to about 10% w/w of total weight of the composition; and at least one C1-C4 polyalkylene oxide block copolymer.

According to an embodiment of the present disclosure, an agrochemical concentrate composition comprises: acetamiprid and chlorantraniliprole in a weight ratio of about 2: 1 to about 1 : 1; at least one polyhydric solvent in an amount from about 5% w/w to about 10% w/w of total weight of the composition; and at least one C1-C4 polyalkylene oxide block copolymer.

According to an embodiment of the present disclosure, an agrochemical concentrate composition comprises: acetamiprid and chlorantraniliprole in a weight ratio of about 2: 1; at least one polyhydric solvent in an amount of about 5% w/w of total weight of the composition; and at least one C1-C4 polyalkylene oxide block copolymer.

According to an embodiment of the present disclosure, an agrochemical concentrate composition comprises: acetamiprid and chlorantraniliprole in a weight ratio of about 1 : 1; at least one polyhydric solvent in an amount of about 10% w/w of total weight of the composition; and at least one C1-C4 polyalkylene oxide block copolymer.

According to an embodiment of the present disclosure, the agrochemical concentrate composition comprises: about 1% w/w to about 60%w/w neonicotinoid insecticide, about 0.1% w/w to about 50% w/w diamide insecticide; about 0.1% w/w to about 10% w/w at least one polyhydric solvent; about 0.1% w/w to about 10% w/w at least one C1-C4 polyalkylene oxide block copolymer of total weight of the composition; wherein the neonicotinoid insecticide and the diamide insecticide are in a weight ratio from about 2: 1 to about 1 : 1.

According to an embodiment of the present disclosure, an agrochemical concentrate composition comprises: about 1% w/w to about 50% w/w neonicotinoid insecticide; about 0.1% w/w to about 40% w/w diamide insecticide; about 0.5% w/w to about 10% w/w at least one polyhydric solvent; about 0.5% w/w to about 10% w/w at least one C1-C4 polyalkylene oxide block copolymer of total weight of the composition; wherein the neonicotinoid insecticide and the diamide insecticide are in a weight ratio from about 2: 1 to about 1 : 1.

According to an embodiment of the present disclosure, an agrochemical concentrate composition comprises: about 1% w/w to about 40%w/w neonicotinoid insecticide; about 0.1% w/w to about 30% w/w diamide insecticide; about 1% w/w to about 10% w/w at least one polyhydric solvent; about 1% w/w to about 10% w/w at least one C1-C4 polyalkylene oxide block copolymer of total weight of the composition; wherein the neonicotinoid insecticide and the diamide insecticide are in a weight ratio from about 2: 1 to about 1 : 1.

In a preferred embodiment, the present disclosure provides an agrochemical concentrate composition consisting of: a neonicotinoid insecticide; a diamide insecticide; at least one polyhydric solvent; at least one C1-C4 polyalkylene oxide block copolymer; and at least one agrochemically acceptable excipient.

In an embodiment, the composition that can be used in the present disclosure include liquid-based compositions. The compositions of the present disclosure can be formulated in a manner which suits the specific application. The formulation is a liquid formulation. Non-limiting examples of suitable liquid formulations may be emulsion concentrates (EC), suspension concentrates (SC), flowable concentrate for seed treatment (FS), or combinations thereof.

According to an embodiment of the present disclosure, the agrochemical concentrate composition is in form of a suspension concentrate (SC) or flowable concentrate for seed treatment (FS).

In a preferred embodiment, the agrochemical concentrate composition is in a form of a suspension concentrate (SC).

In a preferred embodiment, the agrochemical concentrate composition is in a form of a flowable concentrate for seed treatment (FS).

According to an embodiment of the present disclosure, a suspension concentrate (SC) agrochemical composition comprises: about 1% w/w to about 60% w/w neonicotinoid insecticide; about 0.1% w/w to about 50% w/w diamide insecticide; about 0.1% w/w to about 10% w/w at least one polyhydric solvent; about 0.1% w/w to about 10% w/w C1-C4 polyalkylene oxide block copolymer of total weight of the composition; wherein the neonicotinoid insecticide and the diamide insecticide are in a weight ratio from about 2: 1 to about 1 : 1.

In a preferred embodiment, the present disclosure provides a suspension concentrate agrochemical composition consisting of: acetamiprid; chlorantraniliprole; oxirane, methyl-, polymer with oxirane, monobutyl ether; acrylic copolymer solution; mineral oil; xanthan gum and/or smectite clay; propylene glycol;

BIT solution; and silicone emulsion.

According to an embodiment of the present disclosure, a flowable concentrate for seed treatment (FS) agrochemical composition comprises: about 1% w/w to about 60%w/w neonicotinoid insecticide; about 0.1% w/w to about 50% w/w diamide insecticide; about 0.1% w/w to about 10% w/w at least one polyhydric solvent; about 0.1% w/w to about 10% w/w C1-C4 polyalkylene oxide block copolymer of total weight of the composition; wherein the neonicotinoid insecticide and the diamide insecticide are in a weight ratio from about 2: 1 to about 1 : 1.

In a preferred embodiment, the present disclosure provides a flowable concentrate agrochemical composition consisting of: acetamiprid; chlorantraniliprole;

EO-PO block copolymer;

Sodium lignosulphonate; glycerin; micro-fibrillated cellulose; hydrotreated light paraffinic distillate; propylene glycol; organic azo pigment; xanthan gum; l,2-benzisothiazolin-3-onel; acetic acid; and non-ionic aqueous emulsion of polydimethylsiloxane.

According to an embodiment of the present disclosure, an agrochemical concentrate composition comprises: about 1% w/w to about 60%w/w acetamiprid; about 0.1% w/w to about 50% w/w chlorantraniliprole; about 0.1% w/w to about 10% w/w propylene glycol; and about 0.1% w/w to about 10% w/w C1-C4 polyalkylene oxide block copolymer of total weight of the composition.

According to an embodiment of the present disclosure, the agrochemical concentrate composition comprises: about 1% w/w to about 60%w/w acetamiprid; about 0.1% w/w to about 50% w/w chlorantraniliprole; about 0.1% w/w to about 10% w/w at least one polyhydric solvent selected from propylene glycol, glycerin, or combinations thereof; about 0.1% w/w to about 10% w/w C1-C4 polyalkylene oxide block copolymer of total weight of the composition; wherein acetamiprid and chlorantraniliprole are in a weight ratio from about 2: 1 to about 1 : 1; and wherein said composition is in a form of a suspension concentrate (SC) or flowable concentrate for seed treatment (FS).

According to an embodiment of the present disclosure, the agrochemical concentrate composition comprises: about 1% w/w to about 60% w/w acetamiprid; about 0.1% w/w to about 50% w/w chlorantraniliprole; about 0.1% w/w to about 10% w/w propylene glycol; about 0.1% w/w to about 10% w/w C3 polyalkylene oxide block copolymer of total weight of the composition; wherein acetamiprid and chlorantraniliprole are in a weight ratio from about 2: 1 to about 1 : 1; and wherein said composition is in a form of a suspension concentrate (SC).

According to an embodiment of the present disclosure, an agrochemical concentrate composition comprises: about 1% w/w to about 60%w/w acetamiprid; about 0.1% w/w to about 50% w/w chlorantraniliprole; about 0.1% w/w to about 10% w/w glycerin; about 0.1% w/w to about 10% w/w C4 polyalkylene oxide block copolymer of total weight of the composition; wherein acetamiprid and chlorantraniliprole are in a weight ratio from about 2: 1 to about 1 : 1; and wherein said composition is in a form of a flowable concentrate for seed treatment (FS).

According to an embodiment of the present invention, the agrochemical concentrate composition has a particle size distribution (D50) of less than about 15.0 microns.

According to an embodiment of the present invention, the agrochemical concentrate composition has a particle size distribution (D50) of less than about 10.0 microns.

According to an embodiment of the present invention, the agrochemical concentrate composition has a particle size distribution (D50) of less than about 7.0 microns.

According to an embodiment of the present invention, the agrochemical concentrate composition has a particle size distribution (D50) of less than about 5.0 microns. According to an embodiment of the present invention, the agrochemical concentrate composition has a particle size distribution (D50) in range from about 1.0 micron to about 15 microns.

According to an embodiment of the present disclosure, the agrochemical composition further comprises at least one agrochemically acceptable excipient.

In an embodiment of the present disclosure, an agrochemical concentrate composition comprises: a neonicotinoid insecticide; a diamide insecticide; at least one polyhydric solvent; at least one C1-C4 polyalkylene oxide block copolymer; and at least one agrochemically acceptable excipient.

According to an embodiment of the present disclosure, the agrochemically acceptable excipient comprises is selected from the group comprising antifreeze agent(s), wetting agent(s), filler(s), surfactant(s), adjuvant(s), structuring agent(s), thickening agent(s), suspending agent(s), adhesion agent(s), pH-regulating agents, preservative(s), biocides, antifoaming agent(s), colorant(s), solvent(s)/carrier(s)/diluent(s), or combinations thereof.

According to an embodiment of the present disclosure, the surfactant(s) are selected from non-ionic and anionic class of surfactants. According to an embodiment of the present disclosure, anionic surfactants are selected the group comprising alkyl and aryl sulfates and sulfonates, including sodium alkyl sulfates, sodium mono- and dialkyl naphthalene sulfonates, sodium alpha-olefin sulfonate, lignin and its derivatives (such as lignosulfonate salts), sodium lignosulphonate, sodium alkane sulfonates, polyoxyalkylene alkylether sulfate, polyoxyalkylene alkyl aryl ether sulfates, polyoxy-alkylene styrylphenyl ether sulfate, mono- and di- alkylbenzene sulfonates, alkylnaphthalene sulfonate, alkylnaphthalene sulfonate formaldehyde condensate, alkyl diphenylether sulfonates, alkylphosphates, polyoxyalkylene alkyl phosphates, polyoxyalkylene phenylether phosphate, polyoxyalkylphenol phosphates, poly-carboxylates, fatty acids and salts thereof, alkyl glycinates, sulfonated methyl esters, sulfonated fatty acids, sulfosuccinates and their derivatives, acyl glutamates, acyl sarcosinates, alkyl sulfoacetates, acylated peptides, alkyl ether carboxylates, acyl lactylates, or combinations thereof.

According to an embodiment of the present disclosure, the non-ionic surfactants are selected from the group comprising ethoxylated fatty acids, alcohol ethoxylates, tri styrylphenol ethoxylates, ethoxylated sorbitan fatty acid esters (examples include polyoxyethylene sorbitan esters widely known as polysorbates), or combinations thereof.

According to an embodiment of the present disclosure, the suitable antifreeze agent(s) that can be added to the agrochemical concentrate composition are liquid polyols, for example ethylene glycol, propylene glycol, glycerol, or combinations thereof.

According to an embodiment of the present disclosure, the wetting agent(s) that can be added to the agrochemical concentrate composition of the present disclosure include but are not limited to polyarylalkoxylated phosphate esters and their potassium salts. Other suitable wetting agents include sodium dioctylsulfosuccinates and ethoxylated alcohols.

According to an embodiment of the present disclosure, the preferred antifoaming agent(s) is selected from the group comprising silicone-based compounds, alcohols, glycol ethers, mineral spirits, acetylene diols, polysiloxanes, organosiloxanes, siloxane glycols, reaction products of silicon dioxide and organosiloxane polymer, polydimethylsiloxanes, polydimethylsiloxanes oil, polydimethylsiloxanes antifoam emulsion, silicone emulsion, non-ionic aqueous emulsion of polydimethyl siloxane, polyalkylene glycols, or combinations thereof. According to an embodiment of the present disclosure, the examples of an adjuvant include mineral oil and the like.

According to an embodiment of the present disclosure, the examples of a structuring agent include smectite clay and the like.

According to an embodiment of the present disclosure, the examples of thickening agent(s) based on anionic heteropolysaccharides are from the xanthan gum group.

According to an embodiment of the present disclosure, the examples of a suspending agent include micro-fibrillated cellulose and the like.

According to an embodiment of the present disclosure, the examples of an adhesion agent include hydrotreated light paraffinic distillate, white mineral oil, and the like.

According to an embodiment of the present disclosure, the examples of a pH- regulating agent include acetic acid and the like.

According to an embodiment of the present disclosure, the preservative(s) used may be benzisothiazolinone or phenols, 2-bromo-2-nitropropane-l,3-diol, 5-chloro-2- methyl-4-isothiazolin-3-one and 2 methyl-4-isothiazolin-3 one, Glutaraldehyde, Chloromethylisothiazolinone (CMIT)/Methylisothiazolinone (MIT), 2.2-dibromo- 3-nitrilopropioamide, Natamycin and Nisin, Bronopol/CMIT/MIT, or combinations thereof.

In an embodiment, the biocide(s) used may be l,2-benzisothiazolin-3-one, 20% aqueous solution of l,2-benzisothiazolin-3-one in dipropylene glycol, benzisothiazolinone (BIT) solution, or combinations thereof. According to an embodiment of the present disclosure, the colorant(s) (for example in red, blue and green) are, preferably, pigments, which are sparingly soluble in water, and dyes, which are water-soluble. Examples are inorganic coloring agents (for example iron oxide, titanium oxide, and iron hexacyanoferrate) and organic coloring agents (for example alizarin, organic azo pigment, and phthalocyanin coloring agents).

According to an embodiment of the present disclosure, the filler(s) may include an organic or inorganic solid inert substance such as talc, clay, diatomaceous earth, magnesium aluminum silicate, white carbon black, pyrophyllite, light calcium carbonate, high clay, organic bentonite, smectite clay, or combinations thereof.

According to an embodiment of the present disclosure, the examples of solvent/carrier/diluent include water and the like.

In an embodiment, the agrochemically acceptable excipients are present in an amount ranging from about 0.1% w/w to about 30% w/w of total weight of the composition.

In an embodiment, the agrochemically acceptable excipients are present in an amount ranging from about 0.1% w/w to about 20% w/w of total weight of the composition.

In an embodiment, the agrochemically acceptable excipients are present in an amount ranging from about 0.1% w/w to about 10% w/w of total weight of the composition.

According to an embodiment of the present disclosure, an agrochemical concentrate composition comprises: about 1% w/w to about 60% w/w neonicotinoid insecticide; about 0.1% w/w to about 50% w/w diamide insecticide; about 0.1% w/w to about 10% w/w at least one polyhydric solvent; about 0.1% w/w to about 10% w/w C1-C4 polyalkylene oxide block copolymer; and about 0.1% w/w to about 30% w/w at least one agrochemically acceptable excipient of total weight of the composition.

According to an embodiment, the present disclosure provides an agrochemical concentrate composition in a form of a pre-formulated (pre-mix) formulation.

In an embodiment of the present disclosure, a pre-mix agrochemical concentrate composition comprises: a neonicotinoid insecticide; a diamide insecticide; at least one polyhydric solvent; at least one C1-C4 polyalkylene oxide block copolymer; and at least one agrochemically acceptable excipient.

Accordingly in an embodiment, the agrochemical concentrate composition disclosed herein may be applied together as a pre-mix formulation.

In an embodiment, the present disclosure provides a process for preparation of the agrochemical concentrate composition, more particularly suspension concentrate (SC) composition or flowable concentrate for seed treatment (FS) composition.

According to an embodiment of the present disclosure, a process of preparing an agrochemical concentrate composition comprises: admixing a neonicotinoid insecticide, a diamide insecticide, at least one polyhydric solvent in an amount from about 0.1% w/w to about 10% w/w of total weight of the composition; and at least one C1-C4 polyalkylene oxide block copolymer to obtain the agrochemical concentrate composition; wherein the neonicotinoid insecticide and the diamide insecticide are in a weight ratio from about 2: 1 to about 1 : 1. According to an embodiment, the present disclosure provides a process for preparing an agrochemical concentrate composition comprising:

(a) admixing at least one polyhydric solvent in an amount from about 0.1% w/w to about 10% w/w of total weight of the composition, at least one C1-C4 polyalkylene oxide block copolymer and optionally at least one agrochemically acceptable excipient to obtain a mixture;

(b) adding a neonicotinoid insecticide and a diamide insecticide to the mixture of step (a);

(c) milling the mixture to obtain a uniform dispersion with a desired particle size; and

(d) jellifying the dispersion to obtain the agrochemical concentrate composition.

According to an embodiment, the present disclosure provides a process for preparing a suspension concentrate composition, the process comprising:

(a) admixing acetamiprid, chlorantraniliprole, propylene glycol in an amount from about 0.1% w/w to about 10% w/w of total weight of the composition, and at least one C1-C4 polyalkylene oxide block copolymer to obtain a mixture;

(b) milling the mixture to obtain a uniform dispersion with a desired particle size (Dso) less than about 15 microns; and

(c) jellifying the dispersion to obtain the suspension concentrate composition.

According to an embodiment of the present disclosure, the agrochemical concentrate composition prepared is subjected to particle size reduction by milling the mixture of active ingredients, polyhydric solvent, C1-C4 polyalkylene oxide block copolymer and agrochemically acceptable excipients. Suitable devices for this purpose are the devices that offer milling operations such as high shear mixers like ROS high-speed milling (HSM), Ultra-Turrax® apparatus, and dissolvers, static mixers such as systems having mixing nozzles, bead mills, vibratory mills, agitator bead mills, colloid mills, cone mills, circulating mills (agitator ball mills with pin grinding system), disk mills, annular chamber mills, double cone mills, sprocket dispersers, homogenizers, other homogenizers, or combinations thereof.

According to an embodiment of the present disclosure, the agrochemical concentrate composition is designed to be diluted with water (or a water-based liquid) to form the corresponding end-use agrochemical formulations, typically spray formulations.

According to an embodiment of the present disclosure, the agrochemical concentrate composition has a pH value ranging from about 5 to about 7.

According to an embodiment of the present disclosure, the agrochemical concentrate composition has a variation in pH value of less than about 20%, when the temperature is about 54°C between a time period from about 24 hours to about 28 days.

According to an embodiment of the present disclosure, provided is, use of the agrochemical concentrate composition for controlling pests, the composition comprising: a neonicotinoid insecticide, a diamide insecticide; at least one polyhydric solvent in an amount from about 0.1% w/w to about 10% w/w of total weight of the composition; and at least one C1-C4 polyalkylene oxide block copolymer; wherein the neonicotinoid insecticide and the diamide insecticide are in a weight ratio from about 2: 1 to about 1 : 1.

According to an embodiment of the present disclosure, provided is, use of the agrochemical concentrate composition for controlling pests, the composition comprising: acetamiprid; chlorantraniliprole; at least one polyhydric solvent in an amount from about 0.1% w/w to about 10% w/w of total weight of the composition; and at least one C1-C4 polyalkylene oxide block copolymer; wherein acetamiprid and chlorantraniliprole are in a weight ratio from about 2: 1 to about 1 : 1.

According to an embodiment of the present disclosure, provided is, use of the agrochemical concentrate composition for controlling pests, the composition comprising: about 1% w/w to about 60% w/w acetamiprid; about 0.1% w/w to about 50% w/w chlorantraniliprole; about 0.1% w/w to about 10% w/w at least one polyhydric solvent selected from propylene glycol, glycerin, or combinations thereof; and about 0.1% w/w to about 10% w/w C1-C4 polyalkylene oxide block copolymer of total weight of the composition; wherein acetamiprid and chlorantraniliprole are in a weight ratio from about 2: 1 to about 1 : 1; and wherein said agrochemical concentrate composition is in a form of a suspension concentrate (SC) or a flowable concentrate for seed treatment (FS).

According to an embodiment of the present disclosure, a method of controlling pests by applying to a plant, or a locus at which the plant is growing or intended to be grown, or a plant propagation material, or a habitat area thereof, an insecticidally effective amount of an agrochemical concentrate composition comprising a neonicotinoid insecticide, a diamide insecticide, at least one polyhydric solvent in an amount from about 0.1% w/w to about 10% w/w of total weight of the composition, and at least one C1-C4 polyalkylene oxide block copolymer; wherein the neonicotinoid insecticide and the diamide insecticide are in a weight ratio from about 2: 1 to about 1 : 1. According to an embodiment of the present disclosure, a method of controlling undesired insects comprises applying to the insects/pests or to their locus thereof, an insecticidally effective amount of an agrochemical concentrate composition comprising a neonicotinoid insecticide, a diamide insecticide, at least one polyhydric solvent in an amount from about 0.1% w/w to about 10% w/w of total weight of the composition, and at least one C1-C4 polyalkylene oxide block copolymer; wherein the neonicotinoid insecticide and the diamide insecticide are in a weight ratio from about 2: 1 to about 1 : 1.

According to an embodiment of the present disclosure, a method of controlling undesired insects comprises applying to the insects/pests or to their locus thereof, an insecticidally effective amount of an agrochemical concentrate composition comprising acetamiprid, chlorantraniliprole, at least one polyhydric solvent in an amount from about 0.1% w/w to about 10% w/w of total weight of the composition, and at least one C1-C4 polyalkylene oxide block copolymer; wherein acetamiprid and chlorantraniliprole are in a weight ratio of about 2: 1.

According to an embodiment of the present disclosure, a method of controlling undesired insects comprises applying to the insects or to their locus thereof, an insecticidally effective amount of an agrochemical concentrate composition comprising acetamiprid, chlorantraniliprole, at least one polyhydric solvent in an amount from about 0.1% w/w to about 10% w/w of total weight of the composition, and at least one C1-C4 polyalkylene oxide block copolymer; wherein acetamiprid and chlorantraniliprole are in a weight ratio of about 1 : 1.

According to an embodiment of the present disclosure, the agrochemical concentrate composition comprising acetamiprid, chlorantraniliprole, at least one polyhydric solvent in an amount from about 0.1% w/w to about 10% w/w of total weight of the composition, and at least one C1-C4 polyalkylene oxide block copolymer, is used as an insecticide to control insect pests population that are responsible for the damage to the plants/crops. In an embodiment, the insect pest may be from Lepidopteran, Coleopteran, Hemipteran, or Homopteran species. However, the choice of the target insect pests is not limiting.

In an embodiment, Lepidopteran pest species which negatively impact agriculture include, but are not limited to, Ach37iziphnata, Adoxophyes spp., Adoxophyes orana. Agrotis spp. (cutworms), Agrotis ipsdon (black cutworm), Alabama argillacea (cotton leafworm), Amorbia cuneana. Amyelosis transitella (navel orangeworm), Anacamptodes defectaria, Anarsia lineatella (peach twig borer), Anomis sabulifera (jute looper), Anticarsia gemmatalis (velvetbean caterpillar), Archips argyrospila (fruittree leafroller), Archips rosana (rose leaf roller), Argyrotaenia spp. (tortricid moths), Argyrotaenia citrana (orange tortrix), Autographa gamma, Bonagota cranaodes, Borbo cinnara (rice leaf folder), Bucculatrix thurberiella (cotton leafperforator), Caloptilia spp. (leaf miners), Capua reticulana, Carposina niponensis (peach fruit moth), Chilo spp., Chlumetia transversa (mango shoot borer), Choristoneura rosaceana (obliquebanded leafroller), Chrysodeixis spp., Cnaphalocerus medinalis (grass leafroller), Colias spp., Conpomorpha cramerella, Cossus cossus (carpenter moth), Crambus spp. (Sod webworms), Cydia funebrana (plum fruit moth), Cydia molesta (oriental fruit moth), Cydia nignicana (pea moth), Cydia pomonella (codling moth), Darna diducta, Diaphania spp. (stem borers), Diatraea spp. (stalk borers), Diatraea saccharalis (sugarcane borer), Diatraea graniosella (southwester com borer), Earias spp. (boll worms), Earias insulata (Egyptian bollworm), Elar37iziphiella (rough northern bollworm), Ecdytopopha aurantianum, Elasmopalpus lignosellus (lesser comstalk borer), Epiphysias postruttana (light brown apple moth), Ephestia spp. (flour moths), Ephestia cautella (almond moth), Ephestia elutella, Ephestia kuehniella (Mediterranean flour moth), Epimeces spp. , Epinotia aporema, Erionota thrax (banana skipper), Eupoecilia ambiguella (grape berry moth), Euxoa auxiliaris (army cutworm), Feltia spp. (cutworms), Gortyna spp. (stemborers), Grapholita molesta (oriental fruit moth), Hedyle iziphincata (bean leaf webber), Helicoverpa spp. (noctuid moths), Helicoverpa armigera (cotton bollworm), Helicoverpa zea (bollworm/com earworm), Heliothis spp. (noctuid moths), Heliothis virescens (tobacco budworm), Hellula undalis (cabbage webworm), Indarbela spp. (root borers), Keiferia ly coper sicella (tomato pinworm), Leucinodes orbonalis (eggplant fruit borer), Leucoptera malifoliella. Lithocollectis spp., Lobesia botrana (grape fruit moth), Loxagrotis spp. (noctuid moths), Loxagrotis albicosta (western bean cutworm), Lymantria dispar (gypsy moth), Lyonetia clerkella (apple leaf miner), Mahasena corbetti (oil palm bagworm), Malacosoma spp. (tent caterpillars), Mamestra brassicae (cabbage armyworm), Maruca testulalis (bean pod borer), Metisa plana (bagworm), Mythimna unipuncta (true armyworm), Neoleucinodes elegantalis (small tomato borer), Nymphula depunctalis (rice caseworm), Operophthera brumata (winter moth), Ostrinia nubilalis (European corn borer), Oxydia vesulia, Pandemis cerasana (common currant tortrix), Pandemis heparana (brown apple tortrix), Papilio demodocus, Pectinophora gossypiella (pink bollworm), Peridroma spp. (cutworms), Peridroma saucia (variegated cutworm), Perileucoptera coffeella (white coffee leafminer), Phthorimaea operculella (potato tuber moth), Phyllocnisitis citrella, Phyllonorycter spp. (leafminers), Pieris rapae (imported cabbageworm), Plathypena scabra, Plodia interpunctella (Indian meal moth), Plutella xylostella (diamondback moth), Polychrosis viteana (grape berry moth), Prays endocarpa, Prays oleae (olive moth), Pseudaletia spp. (noctuid moths), Pseudaletia unipunctata (armyworm), Pseudoplusia includens (soybean looper), Rachiplusia nu, Scirpophaga incertulas, Sesamia spp. (stemborers), Sesamia inferens (pink rice stem borer), Sesamia nonagrioides, Setora nitens, Sitotroga cerealella (Angoumois grain moth), Sparganothis pilleriana, Spodoptera spp. (armyworms), Spodoptera exigua (beet armyworm), Spodoptera fugiperda (fall armyworm), Spodoptera oridania (southern armyworm), Synanthedon spp. (root borers), Thermisia gemmatalis, Tineola bisselliella (webbing clothes moth), Trichoplusia ni (cabbage looper), Tula absoluta, Yponomeuta spp., Zeuzera coffeae (red branch borer) and Zeuzera pyrina (leopard moth). In another embodiment, the insect pests of the order Orthoptera which negatively impact agriculture include but are not limited to Anabrus simplex (Mormon cricket), Gryllotalpidae (mole crickets), Locusta migratoria, Melanoplus spp. (grasshoppers), Microcentrum retinerve (angularwinged katydid), Pterophylla spp. (kaydids), chistocerca gregaria, Scudde iziphicata (forktailed bush katydid) and Valanga nigricorni.

In another embodiment, the insect pests of the order Thysanoptera, which negatively impact agriculture include, but are not limited to Frankliniella fusca (tobacco thrips), Frankliniella occidentalis (western flower thrips), Frankliniella shultzei Frankliniella williamsi (com thrips), Heliothrips haemorrhaidalis (greenhouse thrips), Riphiphorothrips cruentatus. Scirtothrips spp., Scirtothrips citri (citrus thrips), Scirtothrips dorsalis (yellow tea thrips), Taeniothrips rhopalantennalis and Thrips spp.

In an embodiment, the Coleopteran insect pests may be selected from but not limited to Acanthoscelides spp. (weevils), Acanthoscelides obtectus (common bean weevil), Agrilus planipennis (emerald ash borer), Agriotes spp. (wireworms), Anoplophora glabripennis (Asian longhorned beetle), Anthonomus spp. (weevils), Anthonomus grandis (boll weevil), Aphidius spp., Apion spp. (weevils), Apogonia spp. (grubs), Ataenius spretulus (Black Turgrass Ataenius), Atomaria linearis (pygmy mangold beetle), Aulacophore spp., Bothynoderes punctiventris (beet root weevil), Bruchus spp. (weevils), Bruchus pisorum (pea weevil), Cacoesia spp., Callosobruchus maculatus (southern cow pea weevil), Carpophilus hemipteras (dried fruit beetle), Cass iziphitata, Cerosterna spp, Cerotoma spp. (chrysomeids), Cerotoma trifurcata (bean leaf beetle), Ceutorhynchus spp. (weevils), Ceutorhynchus assimilis (cabbage seedpod weevil), Ceutorhynchus napi (cabbage curculio), Chaetocnema spp. (chrysomelids), Colaspis spp. (soil beetles), Conoderus scalaris, Conoderus stigmosus, Conotrachelus nenuphar (plum curculio), Cotinus nitidis (Green June beetle), Crioceris asparagi (asparagus beetle), Cryptolestes ferrugineus (rusty grain beetle), Cryptolestes pusillus (flat grain beetle), Cryptolestes turcicus (Turkish grain beetle), Ctenicera spp. (wireworms), Curculio spp. (weevils), Cyclocephala spp. (grubs), Cylindr ocpturus adspersus (sunflower stem weevil), Deporaus marginatus (mango leaf-cutting weevil), Dermes40iziphin40rius (larder beetle), Dermestes maculates (hide beetle), Diabrotica spp. (chrysolemids), Epilachna varivestis (Mexican bean beetle), Faustinus cubae. Hylobius pales (pales weevil), Hypera spp. (weevils), Hypera postica (alfalfa weevil), Hyperdoes spp. (Hyperodes weevil), Hypothenemus hampei (coffee berry beetle), Ips spp. (engravers), Lasioderma serricorne (cigarette beetle), Leptinotarsa decemlineata (Colorado potato beetle), Liogenys futscus, Liogenys suturalis. Lissorhoptrus oryzophilus (rice water weevil), Lyctus spp. (wood beetles/powder post beetles), Maecolaspis joliveti, Megascelis spp., Melanotus communis, Meligethes spp., Meligethes aeneus (blossom beetle), Melolontha melolontha (common European cockchafer), Oberea brevis, Oberea linearis, Oryctes rhinoceros (date palm beetle), Oryzaephilus mercator (merchant grain beetle), Oryzaephilus surinamensis (sawtoothed grain beetle), Otiorhynchus spp. (weevils), Oulema melanopus (cereal leaf beetle), Oulema oryzae , Pantomorus spp. (weevils), Phyllophaga spp. (May/June beetle), Phyllophaga cuyabana, Phyllotreta spp. (chrysomelids), Phynchites spp., Popillia japonica (Japanese beetle), Prostephanus truncates (larger grain borer), Rhizopertha dominica (lesser grain borer), Rhynchophorus spp. (weevils), Scolytus spp. (wood beetles), Shenophorus spp. (Billbug), Sitona lineatus (pea leaf weevil), Sitophilus spp. (grain weevils), Sitophilus granaries (granary weevil), Sitophilus oryzae (rice weevil), Stegobium paniceum (drugstore beetle), Tribolium spp. (flour beetles), Tribolium castaneum (red flour beetle), Tribolium confusum (confused flour beetle), Trogoderma variabile (warehouse beetle) and Zabrus tenebioides .

In an embodiment, the insect pests are of the order Hemiptera, such as Acrosternum hilare (green stink bug), Blissus leucopterus (chinch bug), Calocoris norvegicus (potato mind), Cimex hemipterus (tropical bed bug), Cimex lectularius (bed bug), Dagbertus fasciatus, Dichelops furcatus, Dysdercus suturellus (cotton Stainer), Edessa meditabunda, Eurygaster maura (cereal bug), Euschistus heros, Euschistus servus (brown stink bug), Helopeltis antonii, Helopeltis theivora (tea blight plantbug), Lagynotomus spp. (stink bugs), Leptocorisa oratorius, Leptocorisa varicornis, Lygus spp. (plant bugs), Maconellicoccus hir stilus. Neurocolpus longirostris. Nezara viridula (southern green stink bug), Paratrioza cockereHi. Phytocoris spp. (plant bugs), Phytocoris californicus. Phytocoris relativus, Piezodorus guildingi. Poecilocapsus lineatus (fourlined plant bug), Psallus vaccinicola, Pseudacysta perseae, Scaptocoris castanea and Triatoma spp. (bloodsucking conenose bugs/kissing bugs).

In an embodiment, the insect pests are of the order Homoptera, such as Acrythosiphon pisum (pea aphid), Adelges spp. (adelgids), Aleurodes proletella (cabbage whitefly), Aleurodicus disperses, Aleurothrixus floccosus (woolly whitefly), Aluacaspis spp., Amrasca bigutella, Aphrophora spp. (leafhoppers), Aphis spp. (aphids), Aphis gossypii (cotton aphid), Aphis pomi (apple aphid), Aulacorthum solani (foxglove aphid), Bemisia spp. (whiteflies), Bemisia argentifolii, Bemisia tabaci (sweet potato whitefly), Brachycolus noxius (Russian aphid), Brachycorynella asparagi (asparagus aphid), Brevennia rehi, Brevicoryne brassicae (cabbage aphid), Ceroplastes spp. (scales), Ceroplastes rubens (red bawax scale), Chionaspis spp. (scales), Chrysomphalus spp. (scales), Coccus spp. (scales), Dysaphis plantaginea (rosy apple aphid), Empoasca spp. (leafhoppers), Eriosoma lanigerum (woolly apple aphid), Idioscopus nitidulus (mango leafhopper), Laodelphax striatellus (smaller brown planthopper), Lepidosaphes spp., Macrosiphum spp., Macrosiphum euphorbiae (potato aphid), Macrosiphum granarium (English grain aphid), Macrosiphum rosae (rose aphid), Macrosteles quadrilineatus (aster leafhopper), Mahanarva frimbiolata, Metopolophium dirhodum (rose grain aphid), Midis longicornis, Myzus persicae (green peach aphid), Nephotettix spp. (leafhoppers), Nephotettix cindipes (green leafhopper), Nilaparvata lugens (brown planthopper), Parlatoria pergandii (chaff scale), Peregrinus maidis (com delphacid), Philaenus spp. (spittlebugs), Phylloxera vitifoliae (grape phylloxera), Physokermes piceae (spruce bud scale), Pianococcus spp. (mealybugs), Pseudococcus spp. (mealybugs), Pseudococcus brevipes (pine apple mealybug), Quadraspidiotus perniciosus (San Jose scale), Rhapalosiphum spp. (aphids), Rhapalosiphum maida (corn leaf aphid), Rhapalosiphum padi (oat bird-cherry aphid), Saissetia spp. (scales), Saissetia oleae (black scale), Schizaphis graminum (greenbug), Sitobion avenae (English grain aphid), Sogatella furcifera (white-backed planthopper), Therioaphis spp. (aphids), Toumeyella spp. (scales), Toxoptera spp. (aphids), Trialeurodes spp. (whiteflies), Trialeurodes vaporariorum (greenhouse whitefly), Trialeurodes abutiloneus (bandedwing whitefly), Unaspis spp. (scales), Unaspis yanonensis (arrowhead scale) and Zulia entreriana.

Accordingly, the agrochemical concentrate composition of the present disclosure is found to be highly active against a wide variety of insects/pests in various crops.

In an embodiment, the crops can be selected from but not limited to cereals, such as wheat, oats, barley, spelt, triticale, rye, maize, millet, rice, crops such as sugarcane, soybean, sunflower, rape, canola, tobacco, sugar beet, fodder beet; tuber crops such as potatoes, sweet potatoes etc., crops such as asparagus, hops etc., fruit plants such as apples, pears, stone- fruits such as for example peaches, nectarines, cherries, plums, apricots, citrus fruits such as oranges, grapefruit, limes, lemons, kumquats, mandarins, satsumas; nuts such as pistachios, almonds, walnuts, pecan nuts, tropical fruits such as mango, papaya, pineapple, dates, bananas etc., grapes, vegetables such as endives, lambs, lettuce, fennel, globe and loose-leaf salad, chard, spinach, chicory, cauliflower, broccoli, Chinese cabbage, kale (winter kale or curly kale), kohlrabi, Brussel sprouts, red cabbage, white cabbage and savoy, fruiting vegetables such as aubergines, cucumbers, paprika, marrow, tomatoes, courgettes, sweetcorn, root vegetables such as celeriac, turnip, carrots, swedes, radishes, horse radish, beetroot, salsify, celery, pulses such as peas, beans etc., bulb vegetables such as leeks, onions etc., oil crops such as mustard, poppy, olives, sunflowers, coconut, castor oil plants, cocoa beans, groundnuts; fiber crops such as cotton, jute, flex, hemp, crops such as tea, coffee, rubber, ornamentals including shrubs and flowering plants, vines, rangeland and pastures. According to an embodiment, the various components of the agrochemical concentrate composition are used individually or already partially or completely mixed with one another to prepare the agrochemical concentrate composition. It is also possible for the component to be separately packaged and used as a component in a kit of parts.

According to an embodiment of the present disclosure, provided is a kit comprising:

(a) a neonicotinoid insecticide;

(b) a diamide insecticide; wherein the neonicotinoid insecticide and the diamide insecticide are in a weight ratio from about 2: 1 to about 1 : 1;

(c) at least one polyhydric solvent; and

(d) at least one C1-C4 polyalkylene oxide block copolymer; and optionally further comprises:

(e) instructions for use.

(a) a neonicotinoid insecticide;

(b) a diamide insecticide; wherein the neonicotinoid insecticide and the diamide insecticide are in a weight ratio from about 2: 1 to about 1 : 1; at least one polyhydric solvent in an amount from about 0.1% w/w to about 10% w/w of total weight of the composition; and

(c) at least one C1-C4 polyalkylene oxide block copolymer; and optionally further comprises:

(d) instructions for use.

In one embodiment of the disclosure, the kits may include one or more, including all, components that may be used to prepare the agrochemical concentrate composition. E. g., kits may include active ingredients and/or polyhydric solvent in an amount from about 0.1% w/w to about 10% w/w of total weight of the composition and C1-C4 polyalkylene oxide block copolymer system. One or more of the components may already be combined together or pre-formulated. In those embodiments where more than two components are provided in a kit, the components may already be combined together and as such are packaged in a single container such as a vial, bottle, can, pouch, bag or canister.

In a preferred embodiment of the present disclosure, the kit comprises acetamiprid, chlorantraniliprole, at least one polyhydric solvent in an amount from about 0.1% w/w to about 10% w/w of total weight of the composition and at least one C1-C4 polyalkylene oxide block copolymer.

The composition described above is insecticidally active and is stable. It has been found that the polyhydric solvent in an amount from about 0.1% w/w to about 10% w/w of total weight of the composition and at least one C1-C4 polyalkylene oxide block copolymer provided improved stability over time and at various temperatures, and even when the agrochemical composition underwent shear forces for example on mixing. Also, the agrochemical composition obtained had an improved suspensibility, better dispersibility, low or no sedimentation and little particle degradation.

All the features described herein may be combined with any of the above aspects, in any combination. In order that the present disclosure may be more readily understood, reference will now be made, by way of example, to the following description. It will be understood that all tests and physical properties listed have been determined at atmospheric pressure and room temperature (i.e., 25°C), unless otherwise stated herein, or unless otherwise stated in the referenced test methods and procedures.

It will be understood that the specification and examples are illustrative but not limitative of the present disclosure and that other embodiments within the spirit and scope of the disclosure will suggest themselves to those skilled in the art. Other embodiments can be practiced that are also within the scope of the present disclosure. The following examples illustrate the disclosure, but by no means intend to limit the scope of the claims.

EXAMPLES:

Example 1 : Acetamiprid 20% w/w and Chlorantraniliprole 10% w/w Suspension

Concentrate, SC (Working example)

Process:

C4 polyalkylene oxide block copolymer, propylene glycol and water were added in a tank and mixed until a homogeneous mixture was formed. Acetamiprid was added to the mixture under high shear followed by addition of chlorantraniliprole and milled to achieve a particle size D50 of less than or equal to 7 micrometres (pm). Finally, the mixture was gently stirred to obtain the suspension concentrate composition according to the present disclosure.

Example 2: Acetamiprid 20% w/w and Chlorantraniliprole 20% w/w Flowable concentrate for seed treatment, FS (Working example)

Process:

Glycerine and C3 polyalkylene oxide block copolymer were charged into a vessel under continuous stirring and homogenized to obtain a mixture. Acetamiprid and Chlorantraniliprole were then added under high shear and milled to achieve a particle size D50 of less than or equal to 7 pm. Then, the mixture was gently stirred to obtain the flowable concentrate composition according to the present disclosure.

Example 3 : Active Ingredient stability

Composition of Example 1 was taken for active ingredient stability testing. Degradation of acetamiprid and chlorantraniliprole were checked at various stages like in ambient conditions, at accelerated heat stability (AHS) for 2 weeks at 54°C, after 3 months, after 6 months and after 12 months. It was found that acetamiprid and chlorantraniliprole, both remained quite stable in the agrochemical concentrate of the present disclosure with very slight degradation of acetamiprid within acceptable range. (Table 1)

Table 1 : Active ingredient stability

Example 4: Stability study in Real Time

Composition of Example 1 was considered for real time study. To observe crystal growth, particle size of the composition was calculated. Observations were made after 6 months, 12 months and 24 months. The temperature ranges used for the study were 0°C, 25°C and temperature cycling (12/38°C) (T/C) and both D50 and D90 were calculated. It was found that the composition remained quite stable up to 24 months in real time study in various temperature conditions. The composition exhibited all the characteristics of a stable dispersion up to 24 months in real time. (Table 2)

Table 2: Stability study in real time

Example 5: Optimization of polyhydric solvent and C1-C4 polyalkylene oxide block copolymer concentration

While developing a stable composition according to the present disclosure, the inventors of the present disclosure found polyhydric solvent concentration and presence of at least one polyalkylene oxide block copolymer to be critical for regulating the crystal growth. Several compositions (Example 3 & 4) were prepared by varying the quantity of propylene glycol. It was found that higher concentration of propylene glycol in the composition caused crystal growth. Concentration of more than about 10% w/w of total weight of the composition resulted into large crystals such that they were visible to naked eyes. Compositions with polyhydric solvent in higher concentration were found to have controlled particle size in ambient conditions but crystal growth was observed in AHS study conducted at 54°C for 14 days. (Table 3)

Table 3: Concentration of polyhydric solvent and C1-C4 polyalkylene oxide block copolymer

Example 6: Study of crystal growth and other physico-chemical parameters Composition of Example 1 developed according to the present disclosure was evaluated on various physico-chemical parameters. The objective was to identify crystal growth issues especially associated with acetamiprid and also other parameters governing stability of the overall product. 2% dilution was prepared from the composition of Example 1 and sedimentation was measured in water with different hardness, i.e., 57 ppm, 342 ppm and 1026 ppm. The test was conducted on the composition of Example 1 at ambient condition. It was found that all the dilutions remained stable at various hardness with sedimentation less than 1%. This indicates that the agrochemical concentrate composition according to the present disclosure remained stable in shelf as well as at dilution. The pH of the composition was found to be within acceptable range varying from about 6.3 to about 7.1 in ambient and AHS study.

Viscosity was tested in Brookfield Cone/Plate Viscometer using cone with CP-52 specification. Viscosity was tested:

1. In CP52 cone for 2 minutes at 6 rpm; and

2. In CP52 cone for 2 minutes at 60 rpm.

Viscosity remained constant with acceptable variation within 500-616 cps at 6rpm test and also at 60 rpm with an acceptable variation within 100-150 cps.

Further, the particle size of the suspended actives was measured to ensure crystal growth abnormalities. The particle size was analysed by laser diffraction with a Mastersizer 3000. D50 was found to be less than 2 pm and D90 was found to be less than 7 pm. The agrochemical concentrate of Example 1 was also taken for microscopic appearance evaluation. Overall, a stable dispersion was observed in ambient and AHS study. The composition of Example 1 was also analysed on Freeze Thaw (FT) parameters. In this test said composition was subjected to freeze thaw daily cycles (-30°C to ambient temperature) followed by 1 month at 40°C. Sedimentation, viscosity and particle size were found to be well within the acceptable range exhibiting good dispersion after 11 months. Therefore, the composition was found to satisfy all the physico-chemical parameters and remained free from crystal-growth issues. (Table 4)

Table 4: Physico-chemical stability

Example 7: Evaluation of physico-chemical parameters of composition of Example 2

Composition of Example 2 was also evaluated to ascertain the effectiveness of polyhydric solvent in an amount from about 0.1% w/w to about 10% w/w of total weight of the composition and presence of C1-C4 polyalkylene oxide block copolymer in controlling crystal growth issues. It was found that the particle size of the composition of Example 2 remained within acceptable limit with D50 1.39 pm in ambient and 2.02 pm in AHS respectively. Also, D90 remained within acceptable limit with 5.08 pm in ambient and 7.85 pm in AHS respectively. Viscosity of the composition was found to be 460 cps in ambient and 440 cps in AHS study. Overall, composition of Example 2 complied with the ambient and AHS study. (Table-5)

Table 5 : Physico-chemical stability

Example 8: Acetamiprid 200 g/L and Chlorantraniliprole 100 g/L (SC)

Process:

The process of preparation of Example 8 is the same as the process of preparation of Example 1. Example 9: Acetamiprid 19,5% w/w and Chlorantraniliprole 19,5% w/w (FS)

Process:

The process of preparation of Example 9 is the same as the process of preparation of Example 2.

Therefore, inventors of the present disclosure successfully solved crystal growth issues associated with acetamiprid in the agrochemical concentrate composition with more than one active ingredient according to the present disclosure. Presence of at least one polyhydric solvent in an amount from about 0.1% w/w to about 10% w/w of total weight of the composition; and at least one C1-C4 polyalkylene oxide block copolymer in the agrochemical concentrate were found to tackle crystal growth issues and provide stabilizing effect to the composition of the present disclosure. While the present subject matter has been shown and described with reference to preferred embodiments thereof, it will be understood by those skilled in the art that many alternatives, modifications and variations may be made thereto without departing from the spirit and scope thereof. Accordingly, it is intended to embrace all such alternatives, modifications, and variations that fall within the spirit and broad scope of the appended claims.

Claims

We claim:

1. An agrochemical concentrate composition comprising: a neonicotinoid insecticide; a diamide insecticide; at least one polyhydric solvent in an amount from about 0.1% w/w to about 10% w/w of total weight of the composition; and at least one C1-C4 polyalkylene oxide block copolymer.

2. The composition as claimed in claim 1, wherein the neonicotinoid insecticide and the diamide insecticide are in a weight ratio from about 2: 1 to about 1 : 1.

3. The composition as claimed in claim 1, wherein the neonicotinoid insecticide is selected from the group comprising acetamiprid, clothianidin, imidacloprid, nitenpyram, nithiazine, thiacloprid, thiamethoxam, or combinations thereof.

4. The composition as claimed in claim 1, wherein the diamide insecticide is selected from the group comprising chlorantraniliprole, cyantraniliprole, tetraniliprole, tetrachlorantraniliprole, or combinations thereof.

5. The composition as claimed in claim 1, wherein the polyhydric solvent is selected from group comprising propylene glycol, glycerin, or combinations thereof.

6. The composition as claimed in claim 1, wherein the C1-C4 polyalkylene oxide block copolymer is selected from the group comprising 1,2-propylene oxide, butyl block polymer; oxirane, methyl-, polymer with oxirane, monobutyl ether; polyethylene oxide-polypropylene oxide-polyethylene oxide based copolymer; propylene oxide ethylene oxide polymer, ether with ethylene diamine tetrapropanol (4: 1); polyalkylene glycol ether; C4 polyalkylene oxide block copolymer; C3 polyalkylene oxide block copolymer; or combinations thereof. The composition as claimed in claim 1, wherein the composition further comprises at least one agrochemically acceptable excipient selected from the group comprising antifreeze agent, wetting agent, filler, surfactant, adjuvant, structuring agent, thickening agent, suspending agent, adhesion agent, pH- regulating agent, preservative, biocide, antifoaming agent, colorant, solvent, carrier, diluent, or combinations thereof. The composition as claimed in claim 1, wherein the composition comprises: about 1% w/w to about 60% w/w neonicotinoid insecticide; about 0.1% w/w to about 50% w/w diamide insecticide; about 0.1% w/w to about 10% w/w at least one polyhydric solvent; about 0.1% w/w to about 10% w/w at least one C1-C4 polyalkylene oxide block copolymer; and about 0.1% w/w to about 30% w/w at least one agrochemically acceptable excipient of total weight of the composition; wherein the neonicotinoid insecticide and the diamide insecticide are in a weight ratio from about 2: 1 to about 1 : 1. The composition as claimed in claim 1, wherein the composition is in a form of a suspension concentrate or a flowable concentrate. A suspension concentrate composition comprises: about 1% w/w to about 60% w/w acetamiprid; about 0.1% w/w to about 50% w/w chlorantraniliprole; about 0.1% w/w to about 10% w/w propylene glycol; about 0.1% w/w to about 10% w/w C4 polyalkylene oxide block copolymer; and about 0.1% w/w to about 30% w/w at least one agrochemically acceptable excipient of total weight of the composition; wherein acetamiprid and chlorantraniliprole are in a weight ratio of about 2: 1. A flowable concentrate composition comprises: about 1% w/w to about 60% w/w acetamiprid; about 0.1% w/w to about 50% w/w chlorantraniliprole; about 0.1% w/w to about 10% w/w glycerin; about 0.1% w/w to about 10% w/w C3 polyalkylene oxide block copolymer; and about 0.1% w/w to about 30% w/w at least one agrochemically acceptable excipient of total weight of the composition; wherein acetamiprid and chlorantraniliprole are in a weight ratio of about 1 : 1. The composition as claimed in claim 1, wherein a particle size distribution (D50) of the composition is in a range from about 1 micron to about 15.0 microns. A process for preparing an agrochemical concentrate composition as claimed in claim 1, the process comprising:

(d) jellifying the dispersion to obtain the agrochemical concentrate composition. Use of the agrochemical concentrate composition as claimed in claim 1, for controlling pests. A method of controlling pests by applying to a plant, or a locus at which the plant is growing or intended to be grown, or a plant propagation material, or a habitat area thereof, an insecticidally effective amount of an agrochemical concentrate composition as claimed in claim 1.