WO2023202265A1 - Image processing method and apparatus for artifact removal, and device, product and medium - Google Patents

Image processing method and apparatus for artifact removal, and device, product and medium Download PDF

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WO2023202265A1
WO2023202265A1 PCT/CN2023/081283 CN2023081283W WO2023202265A1 WO 2023202265 A1 WO2023202265 A1 WO 2023202265A1 CN 2023081283 W CN2023081283 W CN 2023081283W WO 2023202265 A1 WO2023202265 A1 WO 2023202265A1
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image
artifact
network
level
dictionary
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PCT/CN2023/081283
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French (fr)
Chinese (zh)
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王红
李悦翔
郑冶枫
孟德宇
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腾讯科技(深圳)有限公司
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    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T11/002D [Two Dimensional] image generation
    • G06T11/003Reconstruction from projections, e.g. tomography
    • G06T11/008Specific post-processing after tomographic reconstruction, e.g. voxelisation, metal artifact correction
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06NCOMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N3/00Computing arrangements based on biological models
    • G06N3/02Neural networks
    • G06N3/08Learning methods
    • G06N3/084Backpropagation, e.g. using gradient descent
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T11/002D [Two Dimensional] image generation
    • G06T11/003Reconstruction from projections, e.g. tomography
    • G06T11/006Inverse problem, transformation from projection-space into object-space, e.g. transform methods, back-projection, algebraic methods
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T5/00Image enhancement or restoration
    • G06T5/73Deblurring; Sharpening
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/10Image acquisition modality
    • G06T2207/10072Tomographic images
    • G06T2207/10081Computed x-ray tomography [CT]
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/20Special algorithmic details
    • G06T2207/20081Training; Learning
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/20Special algorithmic details
    • G06T2207/20084Artificial neural networks [ANN]
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2211/00Image generation
    • G06T2211/40Computed tomography
    • G06T2211/421Filtered back projection [FBP]

Definitions

  • the present disclosure relates to the field of artificial intelligence, and more particularly, to image processing for artifact removal.
  • Image processing technology is a technology that uses computers to process image information. It mainly includes image digitization, image enhancement and restoration, image data encoding, image segmentation and image recognition, etc.
  • image restoration technology is to restore the degraded image to its original true appearance as much as possible. For example, it is used in the field of removing artifacts in images, such as removing noise in images, removing raindrops in rainy images taken on rainy days, removing metal artifacts in CT images, etc.
  • current image processing methods face technical bottlenecks such as complex mathematical models, limited application scope, and difficulty in obtaining some data when removing artifacts.
  • the present disclosure provides an image processing method, device, computer equipment, computer program product and storage medium for artifact removal.
  • the image processing method for artifact removal provided by the present disclosure includes: establishing a training data set for training a neural network, wherein the training data set includes multiple groups of image samples, and each group of image samples includes images with artifacts.
  • the adaptive convolutional dictionary network is iteratively trained to optimize network parameters of the adaptive convolutional dictionary network, wherein the adaptive convolutional dictionary network includes a basic artifact dictionary, and the basic artifact dictionary is The convolution dictionary does not change with the sample and includes an artifact convolution kernel, and the adaptation for the image sample is determined by a plurality of artifact convolution kernels in the basic artifact dictionary and a weighting coefficient that changes with the sample.
  • a convolution kernel wherein the artifact image in the artifact-bearing image is determined by convolution of the adaptive convolution kernel with image features of the artifact-bearing image, and from the artifact-bearing image The artifact image is removed to obtain the processed image.
  • the image processing method of the present disclosure can simply and effectively remove artifacts in images to obtain clearer images free from artifact interference.
  • Embodiments of the present disclosure also provide an image processing method for artifact removal, including: obtaining an input image to be processed; using an adaptive convolution dictionary network to process the input image to obtain artifact removal results.
  • the adaptive convolutional dictionary network is trained based on the artifact database (D) and includes a T-level network, wherein the level 1 network outputs level 1 image features and level 1 based on the input image Artifact removal image; the t-th level network outputs the t-level image features and the t-th level artifact based at least in part on the t-1th level image features and the t-1th level artifact removal image output by the t-1th level network.
  • the T-th level network removes the image based on the T-1-th level image features and T-1-th level artifacts output by the T-1-th level network, and outputs the T-th level artifact removal
  • the image is the processed image after artifact removal.
  • An embodiment of the present disclosure provides an image processing device for artifact removal, including: a training data set establishment module configured to: establish a training data set for training a neural network, wherein the training data set includes Multiple sets of image samples, each set of image samples includes an image with artifacts (Y) and its corresponding image without artifacts (X) and image mask (I); the adaptive convolutional dictionary network is configured as: Any group of image samples among the plurality of groups of image samples performs artifact removal processing on the artifact-containing image (Y) to obtain a processed image; the training module is configured to: based on the artifact-free image The adaptive convolutional dictionary network is iteratively trained using the shadow image (X), the processed image, and the objective function processed by the image mask (I) to optimize the performance of the adaptive convolutional dictionary network.
  • the adaptive convolution dictionary network includes a basic artifact dictionary
  • the basic artifact dictionary is a convolution dictionary that does not change with samples and includes an artifact convolution kernel
  • Multiple artifact convolution kernels and weighting coefficients that change with the sample are used to determine the adaptive convolution kernel for the image sample
  • the adaptive convolution kernel and the image features of the image with artifacts are convolution to determine the artifact image in the image with artifacts, and remove the artifact image from the image with artifacts to obtain the processed image.
  • An embodiment of the present disclosure provides an image processing device for artifact removal, including: an image acquisition module configured to: acquire an input image to be processed; an image processing module configured to: utilize an adaptive convolution dictionary A network that processes the input image to obtain a processed image with artifacts removed; wherein the adaptive convolutional dictionary network is trained based on the artifact database (D) and includes a T-level network, wherein the The level 1 network outputs the level 1 image features and the level 1 artifact removal image based on the input image; the level t network is based at least in part on the level t-1 image features and the t-1 level output by the level t-1 network.
  • an image acquisition module configured to: acquire an input image to be processed
  • an image processing module configured to: utilize an adaptive convolution dictionary A network that processes the input image to obtain a processed image with artifacts removed
  • the adaptive convolutional dictionary network is trained based on the artifact database (D) and includes a T-level network, wherein the The level 1 network outputs the
  • the level t artifact removal image outputs the t level image features and the t level artifact removal image, where t is greater than 1 and less than or equal to T; the T level network is based on the T-1 level image features output by the T-1 level network. and the T-1-th level artifact removal image, and the T-th level artifact removal image is output as the processed image after artifact removal.
  • Embodiments of the present disclosure provide a computer program product.
  • the computer program product includes a computer program.
  • the computer program executes the above method.
  • Embodiments of the present disclosure provide a computer-readable storage medium on which a computer program is stored. When the computer program is executed by a processor, the above method is performed.
  • An embodiment of the present disclosure provides a computer device, including:
  • the processor, the communication interface and the memory complete communication with each other through the communication bus;
  • the communication interface is an interface of a communication module;
  • the memory is used to store a computer program and transmit the computer program to the processor; the processor is used to call the computer program in the memory to execute the above method.
  • the image processing method of the present disclosure can perform artifact removal processing only based on the image to be processed without additional Get the chord diagram of the image.
  • the adaptive convolutional dictionary network adopted in this disclosure makes full use of the prior structure of the artifact image, resulting in better artifact removal and stronger model generalization.
  • the mathematical model used in the image processing method of the present disclosure has clear physical meaning and strong interpretability, and the physical meaning of each network module is clearer, which facilitates understanding and application by those skilled in the art.
  • the image processing method of the present disclosure can simply and effectively remove artifacts in images to obtain clearer images free from artifact interference.
  • FIGS. 1A-1B are schematic diagrams respectively showing images with artifacts and images without artifacts according to embodiments of the present disclosure
  • Figures 2A-2B are schematic diagrams showing an image processing method based on chord diagrams
  • 3A-3B are schematic flowcharts illustrating an image processing method for artifact removal according to an embodiment of the present disclosure
  • FIG. 4 is an exemplary schematic diagram illustrating an image processing model based on a weighted adaptive convolution dictionary according to an embodiment of the present disclosure
  • 5A-5B are schematic diagrams illustrating the iterative update process of each level of the network in the adaptive convolutional dictionary network according to an embodiment of the present disclosure
  • FIG. 6 is a schematic flowchart illustrating an image processing process for artifact removal according to an embodiment of the present disclosure
  • FIGS. 7A-7B are schematic diagrams illustrating the composition of an image processing device for artifact removal according to an embodiment of the present disclosure
  • FIG. 8 is an architecture diagram illustrating a computing device according to an embodiment of the present disclosure.
  • FIG. 9 is a schematic diagram illustrating a storage medium according to an embodiment of the present disclosure.
  • the method of the present disclosure may be based on artificial intelligence (AI).
  • Artificial intelligence is a theory, method, technology and application system that uses digital computers or machines controlled by digital computers to simulate, extend and expand human intelligence, perceive the environment, acquire knowledge and use knowledge to obtain the best results.
  • artificial intelligence is a comprehensive technology of computer science that attempts to understand the essence of intelligence and produce a new method that is similar to human intelligence.
  • Intelligent machines that respond. For example, for artificial intelligence-based methods, it can perform machine learning in a manner similar to human perception, such as training neural networks to extract image information, perform image analysis and processing.
  • Image processing technology is a technology that uses computers to process image information. Mainly include: image digitization, image enhancement and restoration, image data encoding, image segmentation and image recognition, etc. At present, image processing technology is mainly implemented based on computers. Artificial Neural Networks (ANN) is an algorithmic mathematical model that simulates the structure and behavior of biological nervous systems and performs distributed parallel information processing. ANN achieves the purpose of processing information by adjusting the weight relationship between internal neurons and neurons. When processing images, the computer uses the original image or appropriately preprocessed image as the input signal of the neural network, and obtains the processed image signal or classification result at the output end of the neural network.
  • ANN Artificial Neural Networks
  • FIG. 1A is a schematic diagram showing an image with artifacts according to an embodiment of the present disclosure.
  • X-ray computed tomography has been widely used in clinical diagnosis.
  • CT X-ray computed tomography
  • metal implants in the patient's body, such as dental fillings and hip prostheses
  • projection data is usually lost, causing severe metal artifacts to appear in the reconstructed CT images.
  • the structure of the metal artifact is a group of striped shadows with similar shapes.
  • the thickness and lightness of the strip shadow will be different.
  • the presence of metal artifacts makes CT images blurred, seriously interfering with the clear presentation of patient body details in CT images, and making it difficult for doctors to make correct judgments based on CT images.
  • an image processing method is needed that can effectively identify artifacts in images and remove them from artifact-bearing images, so that the processed artifact-free image is as shown in Figure 1B.
  • Clear, artifact-free CT images such as those shown in Figure 1B can help doctors make more accurate diagnoses.
  • FIG. 2A shows a schematic diagram of a chord diagram-based image processing method according to an embodiment of the present disclosure.
  • DuDoNet++ is a joint learning scheme based on CT images and chord diagrams.
  • This scheme uses two network modules, SE-Net and IE-Net, to jointly process CT images with metal artifacts.
  • SE -Net is a network module for chord images
  • IE-Net is a network module for CT images.
  • S ma represents the chord image contaminated by metal
  • S se represents the chord image after repair and enhancement
  • X se represents the CT image obtained by S se after reverse projection transformation (RIL)
  • M represents the CT image.
  • the shape characteristics of the metal in the domain ie, mask
  • M p represents the shape characteristics of the metal in the chord diagram domain obtained by M after Radon transformation (FP)
  • X ma represents the CT image with metal artifacts
  • X out represents the output reconstructed image.
  • CT images with metal artifacts need to be processed jointly by the chord image domain (using SE-Net) and the CT image domain (using IE-Net) to achieve the purpose of image artifact removal.
  • chord The transformation between the image domain and the CT image domain is performed through a differentiable Radon transform layer.
  • FIG. 2B shows a schematic diagram of another chord diagram-based image processing method according to an embodiment of the present disclosure.
  • DSCMAR is also a joint processing scheme based on CT image chord diagrams. Different from DuDoNet++, this scheme first uses PriorNet to obtain a cleaner repaired image, and then uses SinoNet to further correct and enhance the chord diagrams. Finally, The reconstructed CT image is obtained through filtered back projection (FBP) transformation.
  • FBP filtered back projection
  • S ma represents the chord diagram contaminated by metal
  • T r represents the chord diagram with metal characteristics
  • S LI represents the chord diagram after linear interpolation
  • X LI represents the chord diagram obtained by S LI after back-projection transformation.
  • CT image X ma represents CT image with metal artifacts Image
  • X prior represents the initial repaired CT image processed by PriorNet
  • S prior represents the initial repaired chord image obtained by forward projection transformation of X prior
  • S res represents the difference obtained by S LI and S prior
  • the chord diagram S corr represents the further modified and enhanced chord diagram processed by SinoNet.
  • the image processing method based on chord diagrams shown in FIGS. 2A and 2B can implement image processing for artifact removal as shown in FIGS. 1A and 1B .
  • the common limitation of DuDoNet++ and DSCMAR is that in these two solutions, the chord diagram information used is difficult to obtain in practice and usually needs to be provided by the equipment manufacturer.
  • the designed network does not embed the prior information unique to the Metal Artifacts Reduction (MAR) task well, and the generalization ability of the network model is limited.
  • MAR Metal Artifacts Reduction
  • each network module included in these two solutions has weak physical interpretability and is not easy to understand and use by those skilled in the art.
  • the present disclosure proposes an image processing method for artifact removal, which can perform reconstruction processing based only on images with artifacts, overcoming the problem of difficulty in obtaining chord diagram data.
  • the image processing method of the present disclosure uses a specific weighted convolution dictionary model to encode the prior structure of the artifact, making the network more reliable and with stronger generalization ability.
  • the adaptive convolutional dictionary network model of the present disclosure has clear physical interpretability and is easy to understand and use by those skilled in the art.
  • FIG. 4 is an exemplary schematic diagram of an image processing model based on a weighted adaptive convolution dictionary according to an embodiment of the present disclosure.
  • the CT image with metal artifacts is the CT image with metal artifacts; H and W are the height and width of the image respectively; ;A is a metallic artifact.
  • the non-metallic region mask I may be known, which is used to focus the solved mathematical model on the non-metallic domain and no longer pay attention to the solution of the metallic domain.
  • the metal artifacts A contained therein basically show a common or similar pattern, that is, strip structures with similar shapes.
  • the artifact patterns contained in different CT images with metal artifacts have some specific attributes, such as pixel intensity.
  • the basic artifact dictionary learned in advance from existing samples to build an adaptive convolution kernel for the image And extract the artifact features of the image Then the adaptive convolution kernel based on this image can be with artifact features
  • the metal artifact A of the image is obtained, thereby realizing the extraction of the metal artifact.
  • the basic artifact dictionary It can be either an existing known basic artifact dictionary or a basic artifact dictionary obtained through training and synthesis of existing samples.
  • a weighted convolution dictionary model can be used to encode the metal artifact A:
  • a common database representing different metal artifact types in all CT images with metal artifacts is the weighting coefficient that changes with the sample;
  • Position; N is the number of real specific convolution kernels used to encode A; It is a two-dimensional plane convolution operation, and p and d are both positive integers.
  • the basic artifact dictionary is a convolutional dictionary that does not change with samples and includes a first number (d) of artifact convolution kernels.
  • the second number of adaptive convolution kernels for the image sample can be determined by a plurality of artifact convolution kernels in the basic artifact dictionary and a weighting coefficient (K) that changes with the sample.
  • equation (2) the model of the non-metallic area corresponding to the final CT image with metal artifacts can be obtained as:
  • FIG. 5A shows a schematic structure of an adaptive convolutional dictionary network according to an embodiment of the present disclosure, which includes a T-level network. In each level of network, the weighting coefficient K, feature layer and clean CT image X are updated.
  • Figure 5B shows a schematic structure of a network at each level according to an embodiment of the present disclosure.
  • 3B is a schematic flowchart 320 illustrating a model usage process of an image processing method for artifact removal according to an embodiment of the present disclosure.
  • the input image to be processed may be an image obtained after applying its corresponding image mask (I) to the original CT image, that is, I ⁇ Y.
  • the input image to be processed may be an image with artifacts, or may be an image with artifacts that has undergone preprocessing (eg, denoising processing, normalization processing).
  • preprocessing eg, denoising processing, normalization processing.
  • the image mask (I) in this disclosure is a mask of the area to be studied or the area of interest.
  • the input image is processed using an adaptive convolutional dictionary network to obtain a processed image with artifacts removed.
  • the adaptive convolutional dictionary network is trained based on the artifact database (D) and includes a T-level network (as shown in Figure 5A), wherein the level 1 network outputs a level 1 image based on the input image Features and level 1 artifact removal images; the t-th level network is based at least in part on the t-1th level image features and the t-1th level artifact removal image output by the t-1th level network, and outputs the t-th level image features and The t-th level artifact removal image, where t is greater than 1 and less than or equal to T; the T-th level network outputs the T-1th level image feature and the T-1th level artifact removal image based on the T-1th level network output
  • the T-level artifact removal image is used as the processed image after artifact removal.
  • the processed image with artifacts removed can be output to the user through a display or through film, drawings, etc.
  • the adaptive convolution dictionary network includes a basic artifact dictionary, which is a convolution dictionary that does not change with the input image and includes an artifact convolution kernel.
  • a basic artifact dictionary which is a convolution dictionary that does not change with the input image and includes an artifact convolution kernel.
  • the t-th level network First, determine the t-th level weighting coefficient of the t-th level network, and then determine the adaptive convolution for the t-th level network through the artifact convolution kernel in the basic artifact dictionary and the t-th level weighting coefficient.
  • convolution kernel then based on the adaptive convolution kernel and the image characteristics of the t-th level network Characteristics determine the t-th level artifact removal image.
  • the number of artifact convolution kernels can be recorded as the first number, which is an integer value greater than 1. This application does not limit the number of adaptive convolution kernels, and their number can be recorded as the second number.
  • each level of the network may include a weighted coefficient update network, an image feature update network, and an artifact removal image update network, wherein the weighted coefficient update network, the image feature update network, and the artifact removal image update network include residual Differential network structure and normalization processing layer.
  • the network structures of the weighted coefficient update network, image feature update network, and artifact removal image update network can be diverse, and the network structure is usually related to the dimensional characteristics of the solution variables corresponding to the network.
  • the weighted coefficient update network solves for coefficients, so it usually includes a linear layer
  • the image feature update network and the artifact removal image update network solve for two-dimensional images, so it usually includes a convolutional layer.
  • the artifact image may be a metal artifact
  • the input image to be processed may be a CT image with metal artifacts
  • the image mask (I) may be the same as a CT image with metal artifacts.
  • each level of the network may include a weighted coefficient update network, a metal artifact image feature update network, and a metal artifact removal image update network, where the weighted coefficient update network, the metal artifact image feature update network, and the metal artifact removal image update network are
  • the artifact removal image update network includes a residual network structure; and the weighted coefficient update network includes: a linear layer, a rectified linear unit (Rectified Linear Unit, ReLU) layer, a cross-link layer, and a batch normalization (Batch Normalization, BN) layer; metal
  • the artifact image feature update network includes: convolution layer, BN layer, ReLU layer, and cross-link layer;
  • the metal artifact removal image update network includes: convolution layer, BN layer, ReLU layer, and cross-link layer.
  • 3A is a schematic flowchart 310 illustrating a neural network training process of an image processing method for artifact removal according to an embodiment of the present disclosure.
  • a training data set for training the neural network is established, wherein the training data set includes multiple groups of image samples, each group of image samples includes an image with artifacts (Y) and its corresponding image without artifacts. (X) and image mask (I).
  • public image libraries and different types of metal masks can be used to synthesize artifacts according to the data simulation process, and the artifact-bearing image and the metal mask corresponding to the artifact-bearing image ( Me ) as training data.
  • the public DeepLesion image library and different types of metal masks to synthesize metal artifacts according to the data simulation process, and convert the CT images with metal artifacts into Images and metal masks are used as training data.
  • the different types of masks or different types of metal masks are used to set the size and shape of the implant in the CT image.
  • establishing a training data set for training a neural network may include: normalizing the pixel values of the image with artifacts (Y).
  • the establishment of a training data set for training a neural network may include: randomly cropping the artifact-bearing image (Y) to obtain image blocks, and classifying all the artifacts according to a predetermined probability.
  • the above image blocks are randomly flipped.
  • the normalized data can also be converted to the [0,255] range to facilitate computer processing.
  • each training image and the corresponding mask can also be randomly cropped to form a smaller image block (for example, it can be an image block of 64x64 pixel size), and then with a predetermined probability (for example, it can be 0.5) Perform random horizontal mirror flipping and random vertical mirror flipping respectively to obtain more diverse training sample data.
  • a predetermined probability for example, it can be 0.5
  • optimization of the network parameters of the adaptive convolutional dictionary network can be achieved by executing the following S312-S313.
  • an adaptive convolutional dictionary network is used to perform artifact removal processing on the image with artifacts (Y) to obtain a processed image.
  • the adaptive convolution dictionary network may include a basic artifact dictionary, which is a convolution dictionary that does not change with samples and includes an artifact convolution kernel, and may The adaptive convolution kernel for the image sample is determined through a plurality of artifact convolution kernels in the basic artifact dictionary and a weighting coefficient that changes with the sample.
  • the artifact image in the artifact-bearing image can be determined by convolving the adaptive convolution kernel with the image features of the artifact-bearing image, and the artifact-bearing image can be removed from the artifact-bearing image. Artifact image to obtain the processed image.
  • the adaptive convolutional dictionary network is iteratively trained based on the artifact-free image (X), the processed image, and the objective function processed by the image mask (I) to optimize Network parameters of the adaptive convolutional dictionary network.
  • the objective function may be a loss objective function constructed based on the artifact-free image (X) and the processed image, wherein the objective function is constructed based on the artifact-free image (X) and the processed image.
  • the processed image and the objective function are used to iteratively train the adaptive convolutional dictionary network to optimize the network parameters of the adaptive convolutional dictionary network, including: calculating the loss objective function and backpropagating the result to the adaptive convolutional dictionary network.
  • the adaptive convolutional dictionary network is described, and the network parameters of the adaptive convolutional dictionary network are optimized based on the adaptive moment estimation (Adaptive moment estimation, Adam) algorithm.
  • the objective function may also be a loss objective function constructed based on the artifact-free image (X) and the processed image and processed by the image mask (I).
  • the artifact convolution kernel indicates an artifact pattern
  • the image feature indicates the location of the artifact pattern
  • the adaptive convolution dictionary network includes a T-level network
  • the iterative update rule based on proximal gradient descent is used to update the weighted coefficients and image features output by the t-1 level network to obtain the weighted coefficients and image features of the t-level network, where t is greater than An integer that is 1 and less than or equal to T.
  • each level of the network may include a weighted coefficient update network, an image feature update network, and an artifact removal image update network, wherein the weighted coefficient update network, the image feature update network, and the artifact removal image update network include residual Differential network structure and normalization processing layer.
  • the network structures of the weighted coefficient update network, image feature update network, and artifact removal image update network can be diverse, and the network structure is usually related to the dimensional characteristics of the solution variables corresponding to the network.
  • the weighted coefficient update network solves for coefficients, so it usually includes a linear layer
  • the image feature update network and the artifact removal image update network solve for two-dimensional images, so it usually includes a convolutional layer.
  • the image processing method for artifact removal may further include: after the training is completed, The adaptive convolutional dictionary network was tested to evaluate the effect of image processing.
  • testing the adaptive convolutional dictionary network includes: preprocessing the artifact-bearing image to be tested and inputting it into the adaptive convolutional dictionary network; using the adaptive convolutional dictionary network to The image with artifacts to be tested is processed to obtain a processed image with artifacts removed.
  • the artifact image may be a metal artifact
  • the image with artifacts may be a CT image with metal artifacts. Therefore, the training data set includes multiple groups of CT image samples, each group of image samples includes CT images with metal artifacts and corresponding CT images without metal artifacts;
  • the adaptive convolution dictionary network includes basic metal Artifact dictionary, the basic metal artifact dictionary is a metal artifact convolution dictionary that does not change with CT image samples and includes a metal artifact convolution kernel, and is passed through a plurality of metal artifact volumes in the basic metal artifact dictionary
  • the adaptive convolution kernel for the CT image sample is determined with a weighting coefficient that changes with the CT image sample, wherein the metal artifact convolution kernel indicates a metal artifact pattern, and the image feature indicates the Where the metal artifact pattern is located.
  • each level of the network may include a weighted coefficient update network, a metal artifact image feature update network, and a metal artifact removal image update network, where the weighted coefficient update network
  • the network, the metal artifact image feature update network, and the metal artifact removal image update network include a residual network structure; and the weighted coefficient update network includes: a linear layer, a ReLU layer, a cross-link layer, and a BN layer; metal artifact image features
  • the update network includes: convolution layer, BN layer, ReLU layer, and cross-link layer; the metal artifact removal image update network includes: convolution layer, BN layer, ReLU layer, and cross-link layer.
  • a common database representing different metal artifact types in all CT images with metal artifacts can be It is constructed as a convolution layer, based on which an adaptive convolutional dictionary network is constructed, and the optimized parameters of the adaptive convolutional dictionary network are obtained through end-to-end training on the training data set.
  • ⁇ , ⁇ and ⁇ are compromise parameters
  • f 1 ( ⁇ ), f 2 ( ⁇ ) and f 3 ( ⁇ ) are regular terms, which respectively represent the weighting coefficient K, feature layer and the prior structure of the clean CT image X, which can be designed as a neural network module to solve.
  • proximal gradient technology can be used to alternately update the weighting coefficient K and the feature layer and clean CT image X. details as follows:
  • K can be updated as:
  • ⁇ K
  • ⁇ 1 is the update step size, which can be derived:
  • Equation (7) can be equivalently written as:
  • equation (9) can be written as:
  • is a proximal operator, related to the regular term f 1 ( ⁇ ); ⁇ can be obtained by Introduce a normalization operation to achieve this.
  • Equation (11) can be written as:
  • ACDNet Adaptive Convolutional Dictionary Network
  • FIG. 5A A schematic structure of an adaptive convolutional dictionary network according to an embodiment of the present disclosure is shown in FIG. 5A , which includes a T-level network. In each level of network, the weighting coefficient K, feature layer and processed CT image X are updated. A schematic structure of each level network according to an embodiment of the present disclosure is shown in Figure 5B.
  • ACDNet as shown in Figure 5A is composed of T stages (i.e., T-level network).
  • T stages i.e., T-level network
  • the corresponding network structure consists of K-net, and X-net, which are used to implement K, and iterative updates of X.
  • K-net in It is a residual structure, specifically: linear layer, ReLU layer, linear layer, cross-link layer and normalization operation layer at dimension d;
  • each residual block includes in turn: convolution layer, BN layer, ReLU layer, convolution layer, BN layer, and cross-link layer;
  • X-net in It is composed of 3 residual blocks, and each residual block includes in turn: convolution layer, BN layer, ReLU layer, convolution layer, BN layer, and cross-link layer.
  • the first-level network obtains the first-level image feature M (1) and the first-level artifact removal image X (1) output by the first-level network based on the input image; the t-level network at least partially Based on the t-1th level image feature M (t-1) output by the t-1th level network and the t-1th level artifact removal image X (t-1) , obtain and output the t-th level network output
  • the t-th level image feature M (t) and the t-th level artifact removal image X (t) where t is greater than 1 and less than or equal to T;
  • the T-th level network is based on the T-1 level image output by the T-1 level network Feature M (T-1) and T-1th level artifact removal image X (T-1) , obtain and output the Tth level artifact removal image X (T) output by the Tth level network as the artifact removal image The processed image of the shadow.
  • the iterative solution process is shown in Figure 5B.
  • the weighted coefficients and image features output by the t-1 level network are updated using the iterative update rule based on proximal gradient descent to obtain the weighting coefficients and image features of the t-level network, where t is an integer greater than 1 and less than or equal to T.
  • K-net, M-net, and X-net are solved iteratively in a serial manner.
  • the adaptive convolutional dictionary network can be iteratively trained based on the artifact-free image (X), the processed image, and the objective function processed by the image mask (I) to optimize the network of the adaptive convolutional dictionary network.
  • the objective function may be a loss objective function constructed based on the artifact-free image (X) and the processed image, that is,
  • ⁇ t is the compromise parameter
  • ⁇ 1 and ⁇ 2 are the weights used to balance various losses.
  • the optimization parameters can be updated and solved based on the Adam algorithm, including: Convolution kernel Step sizes eta 1 , eta 2 and eta 3 .
  • the prediction result error is calculated and back-propagated to the convolutional neural network model, the gradient is calculated and the parameters of the convolutional neural network model are updated.
  • FIG. 6 is a schematic flowchart illustrating an image processing process for artifact removal according to an embodiment of the present disclosure.
  • the image processing process for artifact removal includes a neural network training phase and a testing phase.
  • images with artifacts can first be preprocessed to establish a training data set for training the neural network, where the training data set includes multiple groups of image samples, and each group of image samples includes Artifact image (Y) and its corresponding artifact-free image (X) and image mask (I). Then based on the preprocessed image samples, the computer iteratively trains ACDNet according to the neural network training settings. During the training process, the parameters of ACDNet are updated based on the predetermined objective function and the Adam optimization algorithm. If the predetermined number of iterations is reached during the training process, the trained model is saved. If the predetermined number of iterations is not reached, ACDNet continues to be trained.
  • the purpose of using the predetermined number of iterations as the criterion for judging the completion of ACDNet training is to prevent the network from overfitting.
  • the input image to be processed and its corresponding image mask (I) are input to the computer.
  • the computer loads the trained model and obtains the artifact-removed image through ACDNet forward calculation.
  • the computer can output the artifact-removed image.
  • the post-production images are for user reference.
  • FIG. 7A is a schematic diagram 710 showing the composition of an image processing device for artifact removal according to an embodiment of the present disclosure.
  • the device 710 is used for a neural network training process during image processing.
  • the image processing device 710 for artifact removal may include: a training data set establishment module 711, an adaptive convolutional dictionary network 712, and a training module 713.
  • the training data set establishment module 711 can be configured to: establish a training data set for training the neural network, wherein the training data set includes multiple groups of image samples, and each group of image samples includes images with artifacts (Y ) and its corresponding artifact-free image (X) and image mask (I).
  • the training data set establishment module 711 may be configured to: perform pixel values of the image with artifacts (Y). Perform normalization processing; and ⁇ or, randomly crop the image with artifacts (Y) to obtain image blocks, and perform random flip processing on the image blocks according to a predetermined probability.
  • the adaptive convolutional dictionary network 712 may be configured to: perform artifact removal processing on the artifact-bearing image (Y) for at least one group of image samples among the plurality of groups of image samples to obtain a processed image. .
  • the adaptive convolution dictionary network 712 may include a basic artifact dictionary, which is a convolution dictionary that does not change with samples and includes an artifact convolution kernel.
  • the artifact convolution kernel and the weighting coefficient that change with the sample are used to determine the adaptive convolution kernel for the image sample.
  • the artifact image in the artifact-bearing image can be determined by convolving the adaptive convolution kernel with the image features of the artifact-bearing image, and the artifact-bearing image can be removed from the artifact-bearing image. Artifact image to obtain the processed image.
  • the training module 713 may be configured to iterate the adaptive convolutional dictionary network based on the artifact-free image (X) and the processed image, and an objective function processed by the image mask (I) Train to optimize the network parameters of the adaptive convolutional dictionary network.
  • the objective function may be a loss objective function constructed based on the artifact-free image (X) and the processed image
  • the training module 713 may be configured to: calculate the loss objective function and The results are backpropagated to the adaptive convolutional dictionary network, and the network parameters of the adaptive convolutional dictionary network are optimized based on the Adam algorithm.
  • the artifact convolution kernel indicates an artifact pattern
  • the image feature indicates the location of the artifact pattern
  • the adaptive convolution dictionary network includes a T-level network
  • the iterative update rule based on proximal gradient descent is used to update the weighted coefficients and image features output by the t-1 level network to obtain the weighted coefficients and image features of the t-level network, where t is greater than An integer that is 1 and less than or equal to T
  • each level of the network includes a weighted coefficient update network, an image feature update network, and an artifact removal image update network, wherein the weighted coefficient update network, the image feature update network, and the artifact removal image update network include residual Network structure and normalization processing layer.
  • the image processing device 710 for artifact removal may further include: a testing module 714 configured to: test the adaptive convolutional dictionary network after the training is completed, wherein the Testing the adaptive convolutional dictionary network includes: preprocessing the artifact-containing image to be tested and inputting it into the adaptive convolutional dictionary network; using the adaptive convolutional dictionary network to preprocess the artifact-containing image to be tested.
  • Artifact images are processed to obtain a processed image with artifacts removed.
  • FIG. 7B is a schematic diagram 720 showing the composition of an image processing device for artifact removal according to an embodiment of the present disclosure.
  • the device 720 is used in a model usage process during image processing.
  • the image processing device 720 for artifact removal may include: an image acquisition module 721 and an image processing module 722.
  • the image acquisition module 721 may be configured to: acquire the input image to be processed.
  • the input image to be processed may be an image obtained after applying its corresponding image mask to the original CT image.
  • the image acquisition module 721 may receive the original CT image and its corresponding image mask, and apply its corresponding image mask to the original CT image, thereby acquiring the input image to be processed.
  • the input image to be processed may be an image with artifacts, or may be a pre-processed image (for example Such as denoising processing, normalization processing) images with artifacts.
  • the image processing module 722 may be configured to use an adaptive convolutional dictionary network to process the input image to obtain a processed image with artifacts removed.
  • the adaptive convolutional dictionary network is trained based on the artifact database (D) and includes a T-level network, wherein the level 1 network outputs level 1 image features and level 1 artifacts based on the input image. Remove the image; the t-th level network outputs the t-level image features and the t-th level artifact removal image based at least in part on the t-1 level image features and the t-1 level artifact removal image output by the t-1 level network.
  • D artifact database
  • the T-level network is based on the T-1-th level image features and the T-1-th level artifact removal image output by the T-1-th level network, and outputs the T-th level artifact removal image as The processed image after artifact removal.
  • the adaptive convolution dictionary network includes a basic artifact dictionary, which is a convolution dictionary that does not change with the input image and includes an artifact convolution kernel, which determines the t-th level network
  • the t-level weighting coefficient determines the adaptive convolution kernel for the t-th level network through multiple artifact convolution kernels in the basic artifact dictionary and the t-th level weighting coefficient; and based on the The adaptive convolution kernel and the image features of the t-th level network determine the t-th level artifact removal image.
  • the various example embodiments of the present disclosure may be implemented in hardware or special purpose circuits, software, firmware, logic, or any combination thereof. Some aspects may be implemented in hardware, while other aspects may be implemented in firmware or software that may be executed by a controller, microprocessor, or other computing device. While aspects of embodiments of the present disclosure are illustrated or described as block diagrams, flowcharts, or using some other graphical representation, it will be understood that the blocks, devices, systems, techniques, or methods described herein may be used as non-limiting Examples are implemented in hardware, software, firmware, special purpose circuitry or logic, general purpose hardware or controllers, or other computing devices, or some combination thereof.
  • computing device 3000 may include a bus 3010, one or more CPUs 3020, read only memory (ROM) 3030, random access memory (RAM) 3040, communication port 3050 connected to a network, input/output components 3060, hard disk 3070, etc.
  • the storage device in the computing device 3000 such as the ROM 3030 or the hard disk 3070, can store various data or files used for processing and/or communication of the methods provided by the present disclosure, as well as program instructions executed by the CPU.
  • Computing device 3000 may also include user interface 3080.
  • the architecture shown in FIG. 8 is only exemplary, and when implementing different devices, one or more components in the computing device shown in FIG. 8 may be omitted according to actual needs.
  • Figure 9 shows a schematic diagram 4000 of a storage medium in accordance with the present disclosure.
  • Computer readable instructions 4010 are stored on computer storage medium 4020. When the computer readable instructions 4010 are executed by the processor, the methods according to the embodiments of the present disclosure described with reference to the above figures may be performed.
  • Computer-readable storage media in embodiments of the present disclosure may be volatile memory or non-volatile memory, or may include both volatile and non-volatile memory.
  • Non-volatile memory may be read-only memory (ROM), programmable read-only memory (PROM), erasable programmable read-only memory (EPROM), electrically erasable programmable read-only memory (EEPROM), or flash memory.
  • Volatile memory may be random access memory (RAM), which acts as an external cache.
  • RAM dynamic random access memory
  • DRAM dynamic random access memory
  • SDRAM synchronous dynamic random access memory
  • DDRSDRAM double data rate synchronous dynamic Follow machine access memory
  • ESDRAM enhanced synchronous dynamic random access memory
  • SLDRAM synchronous link dynamic random access memory
  • DR RAM direct memory bus random access memory
  • Embodiments of the present disclosure also provide a computer program product or computer program, which includes a computer program, and the computer program is stored in a computer-readable storage medium.
  • the processor of the computer device reads the computer program from the computer-readable storage medium, and the processor executes the computer program, so that the computer device performs the method according to the embodiment of the present disclosure.
  • each block in the flowchart or block diagrams may represent a module, segment, or portion of code that contains at least one element for implementing the specified logical function. Executable instructions. It should also be noted that, in some alternative implementations, the functions noted in the block may occur out of the order noted in the figures. For example, two blocks shown one after another may actually execute substantially in parallel, or they may sometimes execute in the reverse order, depending on the functionality involved.
  • each block of the block diagram and/or flowchart illustration, and combinations of blocks in the block diagram and/or flowchart illustration can be implemented by special purpose hardware-based systems that perform the specified functions or operations. , or can be implemented using a combination of specialized hardware and computer instructions.
  • first/second embodiment means a certain feature, structure or characteristic related to at least one embodiment of the present disclosure. Therefore, it should be emphasized and noted that “one embodiment” or “an embodiment” or “an alternative embodiment” mentioned twice or more at different places in this specification does not necessarily refer to the same embodiment. . In addition, certain features, structures or characteristics of one or more embodiments of the present disclosure may be combined appropriately.

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Abstract

Provided in the embodiments of the present disclosure are an image processing method and apparatus for artifact removal, and a computer program product and a storage medium. The image processing method in the present disclosure comprises: establishing a training data set used for training a neural network; performing artifact removal processing on an artifact-containing image by using an adaptive convolutional dictionary network, so as to obtain a processed image; and on the basis of an artifact-free image, the processed image, and an objective function which has been subjected to image mask processing, performing iterative training on the adaptive convolutional dictionary network, so as to optimize network parameters of the adaptive convolutional dictionary network. By means of the image processing method in the present disclosure, artifacts in an image can be simply and effectively removed to obtain a clearer image which is not interfered with by the artifacts.

Description

用于伪影去除的图像处理方法、装置、设备、产品和介质Image processing methods, devices, equipment, products and media for artifact removal
本申请要求于2022年04月19日提交中国专利局、申请号为202210408968.2、申请名称为“用于伪影去除的图像处理方法及装置”的中国专利申请的优先权,其全部内容通过引用结合在本申请中。This application claims priority to the Chinese patent application filed with the China Patent Office on April 19, 2022, with application number 202210408968.2 and the application title "Image processing method and device for artifact removal", the entire content of which is incorporated by reference. in this application.
技术领域Technical field
本公开涉及人工智能领域,更具体地,涉及用于伪影去除的图像处理。The present disclosure relates to the field of artificial intelligence, and more particularly, to image processing for artifact removal.
背景技术Background technique
图像作为人类获取信息最重要的来源之一,在各种信息库中占有极大比重。随着计算机技术的快速发展,图像处理已经广泛应用到了人类社会生活的各个方面,如:工业检测、医学、智能机器人等。图像以其生动性和直观性常被应用于各领域来描述和表达事物的特性与逻辑关系,应用范围广泛,因此,图像处理技术的发展及对各领域的信息处理都极为重要。As one of the most important sources for humans to obtain information, images occupy a huge proportion in various information libraries. With the rapid development of computer technology, image processing has been widely used in all aspects of human social life, such as industrial testing, medicine, intelligent robots, etc. Images are often used in various fields to describe and express the characteristics and logical relationships of things due to their vividness and intuitiveness. They have a wide range of applications. Therefore, the development of image processing technology and information processing in various fields are extremely important.
图像处理技术是用计算机对图像信息进行处理的技术。主要包括图像数字化、图像增强和复原、图像数据编码、图像分割和图像识别等。其中,图像复原技术的目的是使退化了的图像尽可能恢复到原来的真实面貌。例如,用于图像中伪影的去除领域,比如对于图像中的噪声进行去除,对于雨天中拍摄的带雨图像中的雨点进行去除,对CT图像中的金属伪影进行去除等。然而,目前的图像处理方法在去除伪影时面临着数学模型复杂、应用范围局限、部分数据获取困难等技术瓶颈。Image processing technology is a technology that uses computers to process image information. It mainly includes image digitization, image enhancement and restoration, image data encoding, image segmentation and image recognition, etc. Among them, the purpose of image restoration technology is to restore the degraded image to its original true appearance as much as possible. For example, it is used in the field of removing artifacts in images, such as removing noise in images, removing raindrops in rainy images taken on rainy days, removing metal artifacts in CT images, etc. However, current image processing methods face technical bottlenecks such as complex mathematical models, limited application scope, and difficulty in obtaining some data when removing artifacts.
因此,需要一种能够应用广泛并有效识别图像中的伪影,将其从带伪影图像中去除的图像处理方法,以帮助人们获得更清晰的,不受伪影干扰的图像。Therefore, there is a need for an image processing method that can be widely used and effectively identify artifacts in images and remove them from artifact-bearing images, so as to help people obtain clearer images without interference from artifacts.
发明内容Contents of the invention
为了解决上述问题,本公开提供了一种用于伪影去除的图像处理方法、装置、计算机设备、计算机程序产品和存储介质。本公开提供的用于伪影去除的图像处理方法包括:建立用于训练神经网络的训练数据集,其中,所述训练数据集包括多组图像样本,每组图像样本包括带伪影图像(Y)及与其对应的无伪影图像(X)和图像掩膜(I);对于所述多组图像样本中的任意一组图像样本,利用自适应卷积字典网络,对所述带伪影图像(Y)进行伪影去除处理,以得到处理后图像,基于所述无伪影图像(X)和所述处理后图像、以及经所述图像掩膜(I)处理的目标函数对所述自适应卷积字典网络进行迭代训练,以优化所述自适应卷积字典网络的网络参数,其中,所述自适应卷积字典网络包括基本伪影字典,所述基本伪影字典是不随样本变化的卷积字典并且包括伪影卷积核,并且通过所述基本伪影字典中的多个伪影卷积核与随样本变化的加权系数来确定用于所述图像样本的自适应卷积核,其中,通过所述自适应卷积核与所述带伪影图像的图像特征的卷积来确定所述带伪影图像中的伪影图像,并从所述带伪影图像中去除所述伪影图像以得到所述处理后图像。In order to solve the above problems, the present disclosure provides an image processing method, device, computer equipment, computer program product and storage medium for artifact removal. The image processing method for artifact removal provided by the present disclosure includes: establishing a training data set for training a neural network, wherein the training data set includes multiple groups of image samples, and each group of image samples includes images with artifacts. (Y) and its corresponding artifact-free image (X) and image mask (I); for any group of image samples among the multiple groups of image samples, use an adaptive convolution dictionary network to The artifact-bearing image (Y) is subjected to artifact removal processing to obtain a processed image, based on the artifact-free image (X), the processed image, and the objective function processed by the image mask (I) The adaptive convolutional dictionary network is iteratively trained to optimize network parameters of the adaptive convolutional dictionary network, wherein the adaptive convolutional dictionary network includes a basic artifact dictionary, and the basic artifact dictionary is The convolution dictionary does not change with the sample and includes an artifact convolution kernel, and the adaptation for the image sample is determined by a plurality of artifact convolution kernels in the basic artifact dictionary and a weighting coefficient that changes with the sample. A convolution kernel, wherein the artifact image in the artifact-bearing image is determined by convolution of the adaptive convolution kernel with image features of the artifact-bearing image, and from the artifact-bearing image The artifact image is removed to obtain the processed image.
通过本公开的图像处理方法能够简单、有效地去除图像中的伪影,以获得更清晰的、不受伪影干扰的图像。The image processing method of the present disclosure can simply and effectively remove artifacts in images to obtain clearer images free from artifact interference.
本公开的实施例还提供了一种用于伪影去除的图像处理方法,包括:获取待处理的输入图像;利用自适应卷积字典网络,对所述输入图像进行处理,以得到去除伪影的处理后 图像,其中,所述自适应卷积字典网络是基于伪影数据库(D)训练的,并且包括T级网络,其中,第1级网络基于所述输入图像输出第1级图像特征和第1级伪影去除图像;第t级网络至少部分基于第t-1级网络输出的第t-1级图像特征和第t-1级伪影去除图像,输出第t级图像特征和第t级伪影去除图像,其中t大于1且小于等于T;第T级网络基于第T-1级网络输出的第T-1级图像特征和第T-1级伪影去除图像,输出第T级伪影去除图像作为所述去除伪影的处理后图像。Embodiments of the present disclosure also provide an image processing method for artifact removal, including: obtaining an input image to be processed; using an adaptive convolution dictionary network to process the input image to obtain artifact removal results. After processing Image, wherein the adaptive convolutional dictionary network is trained based on the artifact database (D) and includes a T-level network, wherein the level 1 network outputs level 1 image features and level 1 based on the input image Artifact removal image; the t-th level network outputs the t-level image features and the t-th level artifact based at least in part on the t-1th level image features and the t-1th level artifact removal image output by the t-1th level network. Remove the image, where t is greater than 1 and less than or equal to T; the T-th level network removes the image based on the T-1-th level image features and T-1-th level artifacts output by the T-1-th level network, and outputs the T-th level artifact removal The image is the processed image after artifact removal.
本公开的实施例提供了一种用于伪影去除的图像处理装置,包括:训练数据集建立模块,被配置为:建立用于训练神经网络的训练数据集,其中,所述训练数据集包括多组图像样本,每组图像样本包括带伪影图像(Y)及与其对应的无伪影图像(X)和图像掩膜(I);自适应卷积字典网络,被配置为:对于所述多组图像样本中的任意一组图像样本,对所述带伪影图像(Y)进行伪影去除处理,以得到处理后图像;训练模块,被配置为:基于所述无伪影图像(X)和所述处理后图像、以及经所述图像掩膜(I)处理的目标函数对所述自适应卷积字典网络进行迭代训练,以优化所述自适应卷积字典网络的网络参数;其中,所述自适应卷积字典网络包括基本伪影字典,所述基本伪影字典是不随样本变化的卷积字典并且包括伪影卷积核,并且通过所述基本伪影字典中的多个伪影卷积核与随样本变化的加权系数来确定用于所述图像样本的自适应卷积核,其中,通过所述自适应卷积核与所述带伪影图像的图像特征的卷积来确定所述带伪影图像中的伪影图像,并从所述带伪影图像中去除所述伪影图像以得到所述处理后图像。An embodiment of the present disclosure provides an image processing device for artifact removal, including: a training data set establishment module configured to: establish a training data set for training a neural network, wherein the training data set includes Multiple sets of image samples, each set of image samples includes an image with artifacts (Y) and its corresponding image without artifacts (X) and image mask (I); the adaptive convolutional dictionary network is configured as: Any group of image samples among the plurality of groups of image samples performs artifact removal processing on the artifact-containing image (Y) to obtain a processed image; the training module is configured to: based on the artifact-free image The adaptive convolutional dictionary network is iteratively trained using the shadow image (X), the processed image, and the objective function processed by the image mask (I) to optimize the performance of the adaptive convolutional dictionary network. Network parameters; wherein, the adaptive convolution dictionary network includes a basic artifact dictionary, the basic artifact dictionary is a convolution dictionary that does not change with samples and includes an artifact convolution kernel, and through the basic artifact dictionary Multiple artifact convolution kernels and weighting coefficients that change with the sample are used to determine the adaptive convolution kernel for the image sample, wherein the adaptive convolution kernel and the image features of the image with artifacts are convolution to determine the artifact image in the image with artifacts, and remove the artifact image from the image with artifacts to obtain the processed image.
本公开的实施例提供了一种用于伪影去除的图像处理装置,包括:图像获取模块,被配置为:获取待处理的输入图像;图像处理模块,被配置为:利用自适应卷积字典网络,对所述输入图像进行处理,以得到去除伪影的处理后图像;其中,所述自适应卷积字典网络是基于伪影数据库(D)训练的,并且包括T级网络,其中,第1级网络基于所述输入图像输出第1级图像特征和第1级伪影去除图像;第t级网络至少部分基于第t-1级网络输出的第t-1级图像特征和第t-1级伪影去除图像,输出第t级图像特征和第t级伪影去除图像,其中t大于1且小于等于T;第T级网络基于第T-1级网络输出的第T-1级图像特征和第T-1级伪影去除图像,输出第T级伪影去除图像作为所述去除伪影的处理后图像。An embodiment of the present disclosure provides an image processing device for artifact removal, including: an image acquisition module configured to: acquire an input image to be processed; an image processing module configured to: utilize an adaptive convolution dictionary A network that processes the input image to obtain a processed image with artifacts removed; wherein the adaptive convolutional dictionary network is trained based on the artifact database (D) and includes a T-level network, wherein the The level 1 network outputs the level 1 image features and the level 1 artifact removal image based on the input image; the level t network is based at least in part on the level t-1 image features and the t-1 level output by the level t-1 network. The level t artifact removal image outputs the t level image features and the t level artifact removal image, where t is greater than 1 and less than or equal to T; the T level network is based on the T-1 level image features output by the T-1 level network. and the T-1-th level artifact removal image, and the T-th level artifact removal image is output as the processed image after artifact removal.
本公开的实施例提供了一种计算机程序产品,计算机程序产品包括计算机程序,计算机程序在被处理器运行时,执行上述方法。Embodiments of the present disclosure provide a computer program product. The computer program product includes a computer program. When the computer program is run by a processor, the computer program executes the above method.
本公开的实施例提供了一种计算机可读存储介质,其上存储有计算机程序,计算机程序在被处理器执行时,执行上述方法。Embodiments of the present disclosure provide a computer-readable storage medium on which a computer program is stored. When the computer program is executed by a processor, the above method is performed.
本公开的实施例提供了一种计算机设备,包括:An embodiment of the present disclosure provides a computer device, including:
处理器、通信接口、存储器和通信总线;Processors, communication interfaces, memory and communication buses;
其中,所述处理器、所述通信接口和所述存储器通过所述通信总线完成相互间的通信;所述通信接口为通信模块的接口;Wherein, the processor, the communication interface and the memory complete communication with each other through the communication bus; the communication interface is an interface of a communication module;
所述存储器,用于存储计算机程序,并将所述计算机程序传输给所述处理器;处理器,用于调用存储器中计算机程序执行上述方法。The memory is used to store a computer program and transmit the computer program to the processor; the processor is used to call the computer program in the memory to execute the above method.
本公开的图像处理方法,能够只基于待处理的图像进行伪影去除处理,而不需再额外 获取图像的弦图。本公开采用的自适应卷积字典网络充分利用了伪影图像的先验结构,伪影去除的效果更佳,模型泛化性更强。此外,本公开的图像处理方法所采用的数学模型物理含义清晰、解释性强,每个网络模块的物理含义更明确,方便了本领域技术人员理解和应用。通过本公开的图像处理方法能够简单、有效地去除图像中的伪影,以获得更清晰的、不受伪影干扰的图像。The image processing method of the present disclosure can perform artifact removal processing only based on the image to be processed without additional Get the chord diagram of the image. The adaptive convolutional dictionary network adopted in this disclosure makes full use of the prior structure of the artifact image, resulting in better artifact removal and stronger model generalization. In addition, the mathematical model used in the image processing method of the present disclosure has clear physical meaning and strong interpretability, and the physical meaning of each network module is clearer, which facilitates understanding and application by those skilled in the art. The image processing method of the present disclosure can simply and effectively remove artifacts in images to obtain clearer images free from artifact interference.
附图说明Description of the drawings
在此,附图中:Here, in the attached picture:
图1A-图1B是分别示出根据本公开的实施例的带伪影图像和无伪影图像的示意图;1A-1B are schematic diagrams respectively showing images with artifacts and images without artifacts according to embodiments of the present disclosure;
图2A-图2B是示出一种基于弦图的图像处理方法的示意图;Figures 2A-2B are schematic diagrams showing an image processing method based on chord diagrams;
图3A-图3B是示出根据本公开的实施例的用于伪影去除的图像处理方法的示意性流程图;3A-3B are schematic flowcharts illustrating an image processing method for artifact removal according to an embodiment of the present disclosure;
图4是示出根据本公开实施例的基于加权自适应卷积字典的图像处理模型的示例性示意图;FIG. 4 is an exemplary schematic diagram illustrating an image processing model based on a weighted adaptive convolution dictionary according to an embodiment of the present disclosure;
图5A-图5B是示出根据本公开的实施例的自适应卷积字典网络中各级网络迭代更新过程的示意图;5A-5B are schematic diagrams illustrating the iterative update process of each level of the network in the adaptive convolutional dictionary network according to an embodiment of the present disclosure;
图6是示出根据本公开的实施例的用于伪影去除的图像处理过程的示意性流程图;6 is a schematic flowchart illustrating an image processing process for artifact removal according to an embodiment of the present disclosure;
图7A-图7B是示出根据本公开的实施例的用于伪影去除的图像处理装置的组成示意图;7A-7B are schematic diagrams illustrating the composition of an image processing device for artifact removal according to an embodiment of the present disclosure;
图8是示出根据本公开的实施例的计算设备的架构;以及8 is an architecture diagram illustrating a computing device according to an embodiment of the present disclosure; and
图9是示出根据本公开的实施例的存储介质的示意图。9 is a schematic diagram illustrating a storage medium according to an embodiment of the present disclosure.
具体实施方式Detailed ways
为了使得本公开的目的、技术方案和优点更为明显,下面将参考附图详细描述根据本公开的示例实施例。显然,所描述的实施例仅仅是本公开的一部分实施例,而不是本公开的全部实施例,应理解,本公开不受这里描述的示例实施例的限制。In order to make the objects, technical solutions and advantages of the present disclosure more apparent, example embodiments according to the present disclosure will be described in detail below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present disclosure, rather than all embodiments of the present disclosure, and it should be understood that the present disclosure is not limited to the example embodiments described here.
此外,在本说明书和附图中,具有基本上相同或相似步骤和元素用相同或相似的附图标记来表示,且对这些步骤和元素的重复描述将被省略。Furthermore, in this specification and the drawings, steps and elements that are substantially the same or similar are denoted by the same or similar reference numerals, and repeated descriptions of these steps and elements will be omitted.
此外,在本说明书和附图中,根据实施例,元素以单数或复数的形式来描述。然而,单数和复数形式被适当地选择用于所提出的情况仅仅是为了方便解释而无意将本公开限制于此。因此,单数形式可以包括复数形式,并且复数形式也可以包括单数形式,除非上下文另有明确说明。Furthermore, in this specification and the drawings, elements are described in singular or plural form depending on the embodiment. However, the singular and plural forms are chosen as appropriate for the circumstances presented merely for convenience of explanation and are not intended to limit the disclosure thereto. Thus, the singular may include the plural and the plural may also include the singular unless the context clearly dictates otherwise.
在本说明书和附图中,具有基本上相同或相似步骤和元素用相同或相似的附图标记来表示,且对这些步骤和元素的重复描述将被省略。同时,在本公开的描述中,术语“第一”、“第二”等仅用于区分描述,而不能理解为指示或暗示相对重要性或排序。In this specification and the drawings, steps and elements that are substantially the same or similar are denoted by the same or similar reference numerals, and repeated descriptions of these steps and elements will be omitted. Meanwhile, in the description of the present disclosure, the terms “first”, “second”, etc. are only used to differentiate the description and cannot be understood as indicating or implying relative importance or ordering.
为便于描述本公开,以下介绍与本公开有关的概念。To facilitate describing the present disclosure, concepts related to the present disclosure are introduced below.
本公开的方法可以是基于人工智能(Artificial intelligence,AI)的。人工智能是利用数字计算机或者数字计算机控制的机器模拟、延伸和扩展人的智能,感知环境、获取知识并使用知识获得最佳结果的理论、方法、技术及应用系统。换句话说,人工智能是计算机科学的一个综合技术,它企图了解智能的实质,并生产出一种新的能以人类智能相似的方式 做出反应的智能机器。例如,对于基于人工智能的方法而言,其能够以类似于人类感知的方式来进行机器学习,比如通过训练神经网络来提取图像信息、进行图像分析和处理。The method of the present disclosure may be based on artificial intelligence (AI). Artificial intelligence is a theory, method, technology and application system that uses digital computers or machines controlled by digital computers to simulate, extend and expand human intelligence, perceive the environment, acquire knowledge and use knowledge to obtain the best results. In other words, artificial intelligence is a comprehensive technology of computer science that attempts to understand the essence of intelligence and produce a new method that is similar to human intelligence. Intelligent machines that respond. For example, for artificial intelligence-based methods, it can perform machine learning in a manner similar to human perception, such as training neural networks to extract image information, perform image analysis and processing.
图像处理技术是用计算机对图像信息进行处理的技术。主要包括:图像数字化、图像增强和复原、图像数据编码、图像分割和图像识别等。目前图像处理技术主要基于计算机来实现。人工神经网络(Artificial Neural Networks,ANN)是一种模拟生物神经系统的结构和行为,进行分布式并行信息处理的算法数学模型。ANN通过调整内部神经元与神经元之间的权重关系,从而达到处理信息的目的。在处理图像时,计算机把原始图像或经过适当预处理的图像作为神经网络输入信号,在神经网络的输出端得到处理后的图像信号或分类结果。Image processing technology is a technology that uses computers to process image information. Mainly include: image digitization, image enhancement and restoration, image data encoding, image segmentation and image recognition, etc. At present, image processing technology is mainly implemented based on computers. Artificial Neural Networks (ANN) is an algorithmic mathematical model that simulates the structure and behavior of biological nervous systems and performs distributed parallel information processing. ANN achieves the purpose of processing information by adjusting the weight relationship between internal neurons and neurons. When processing images, the computer uses the original image or appropriately preprocessed image as the input signal of the neural network, and obtains the processed image signal or classification result at the output end of the neural network.
综上所述,本公开的实施例提供的方案涉及人工智能、图像处理、神经网络等计算机技术,下面将结合附图对本公开的实施例进行进一步地描述。To sum up, the solutions provided by the embodiments of the present disclosure involve computer technologies such as artificial intelligence, image processing, and neural networks. The embodiments of the present disclosure will be further described below with reference to the accompanying drawings.
以CT图像为例,图1A是示出根据本公开的实施例的带伪影图像的示意图。Taking a CT image as an example, FIG. 1A is a schematic diagram showing an image with artifacts according to an embodiment of the present disclosure.
X射线计算机断层扫描(CT)已被广泛用于临床诊断。但是,在成像过程中,由于患者体内的金属植入物,比如牙齿填充物和髋关节假体的存在,通常会导致投影数据的丢失,从而引起重建的CT图像中呈现出严重的金属伪影。如图1A所示,该金属伪影的结构呈一组形态类似的条状阴影。对于不同的组织结构和/或金属植入物,条状阴影的粗细及明暗程度会不同。从图1A中可以看出,金属伪影的存在使得CT图像变得模糊,严重干扰了CT图像中对于患者身体细节图像的清晰呈现,不易于医生根据CT图像做出正确的判断。X-ray computed tomography (CT) has been widely used in clinical diagnosis. However, during the imaging process, due to the presence of metal implants in the patient's body, such as dental fillings and hip prostheses, projection data is usually lost, causing severe metal artifacts to appear in the reconstructed CT images. . As shown in Figure 1A, the structure of the metal artifact is a group of striped shadows with similar shapes. For different tissue structures and/or metal implants, the thickness and lightness of the strip shadow will be different. As can be seen from Figure 1A, the presence of metal artifacts makes CT images blurred, seriously interfering with the clear presentation of patient body details in CT images, and making it difficult for doctors to make correct judgments based on CT images.
因此需要一种能够有效识别图像中的伪影,并将其从带伪影图像中去除的图像处理方法,使得经处理后的无伪影图像如图1B所示。通过例如图1B所示清晰的、不受伪影干扰的CT图像,可以帮助医生更准确地做出诊断。Therefore, an image processing method is needed that can effectively identify artifacts in images and remove them from artifact-bearing images, so that the processed artifact-free image is as shown in Figure 1B. Clear, artifact-free CT images such as those shown in Figure 1B can help doctors make more accurate diagnoses.
图2A示出了根据本公开的实施例的一种基于弦图的图像处理方法的示意图。FIG. 2A shows a schematic diagram of a chord diagram-based image processing method according to an embodiment of the present disclosure.
如图2A所示,DuDoNet++是一种基于CT图像和弦图的联合学习方案,该方案使用SE-Net和IE-Net两个网络模块来共同对带金属伪影的CT图像进行处理,其中,SE-Net为针对弦图的网络模块,IE-Net为针对CT图像的网络模块。在图2A中,Sma表示被金属污染的弦图,Sse表示经修复增强后的弦图,Xse表示由Sse经反向投影变换(RIL)后得到的CT图像,M表示CT图像域的金属的形状特征(即,掩膜(Mask)),Mp表示M经拉东变换(FP)后得到的弦图域的金属的形状特征,Xma表示带金属伪影的CT图像,Xout表示输出的重构图像。由图2A可以看出,带金属伪影的CT图像需经过弦图域(利用SE-Net)和CT图像域(利用IE-Net)的共同处理来实现图像去伪影的目的,其中,弦图域与CT图像域之间的变换通过可微分的拉东变换层进行转换。As shown in Figure 2A, DuDoNet++ is a joint learning scheme based on CT images and chord diagrams. This scheme uses two network modules, SE-Net and IE-Net, to jointly process CT images with metal artifacts. SE -Net is a network module for chord images, and IE-Net is a network module for CT images. In Figure 2A, S ma represents the chord image contaminated by metal, S se represents the chord image after repair and enhancement, X se represents the CT image obtained by S se after reverse projection transformation (RIL), and M represents the CT image. The shape characteristics of the metal in the domain (ie, mask), M p represents the shape characteristics of the metal in the chord diagram domain obtained by M after Radon transformation (FP), X ma represents the CT image with metal artifacts, X out represents the output reconstructed image. As can be seen from Figure 2A, CT images with metal artifacts need to be processed jointly by the chord image domain (using SE-Net) and the CT image domain (using IE-Net) to achieve the purpose of image artifact removal. Among them, chord The transformation between the image domain and the CT image domain is performed through a differentiable Radon transform layer.
类似地,图2B示出了根据本公开的实施例的另一种基于弦图的图像处理方法的示意图。Similarly, FIG. 2B shows a schematic diagram of another chord diagram-based image processing method according to an embodiment of the present disclosure.
如图2B所示,DSCMAR也是一种基于CT图像和弦图的联合处理方案,与DuDoNet++不同的是,该方案先采用PriorNet获得较为干净的修复图像,然后再用SinoNet对弦图进一步修正增强,最后通过滤波后投影层(Filtered back projection,FBP)转换得到重构的CT图像。在图2B中,Sma表示被金属污染的弦图,Tr表示金属特征的弦图,SLI表示经线性插值处理后的弦图,XLI表示由SLI经反向投影变换后得到的CT图像,Xma表示带金属伪影的CT图 像,Xprior表示经PriorNet处理后的初始修复CT图像,Sprior表示由Xprior经正向投影变换后得到的初始修复的弦图,Sres表示通过对SLI和Sprior作差值后得到的弦图,Scorr表示经SinoNet处理后的进一步修正增强后的弦图,通过将Scorr进行滤波反向投影变换可以得到无金属伪影的图像。As shown in Figure 2B, DSCMAR is also a joint processing scheme based on CT image chord diagrams. Different from DuDoNet++, this scheme first uses PriorNet to obtain a cleaner repaired image, and then uses SinoNet to further correct and enhance the chord diagrams. Finally, The reconstructed CT image is obtained through filtered back projection (FBP) transformation. In Figure 2B, S ma represents the chord diagram contaminated by metal, T r represents the chord diagram with metal characteristics, S LI represents the chord diagram after linear interpolation, and X LI represents the chord diagram obtained by S LI after back-projection transformation. CT image, X ma represents CT image with metal artifacts Image, X prior represents the initial repaired CT image processed by PriorNet, S prior represents the initial repaired chord image obtained by forward projection transformation of X prior , S res represents the difference obtained by S LI and S prior The chord diagram, S corr represents the further modified and enhanced chord diagram processed by SinoNet. By filtering the back projection transformation of S corr , an image without metal artifacts can be obtained.
图2A和图2B所示的基于弦图的图像处理方法能够实现如图1A和图1B所示意的针对伪影去除的图像处理。然而,DuDoNet++与DSCMAR共同的局限性在于:在这两个方案中,所使用的弦图信息在实际中很难获取,通常需要设备制造商进行提供。而且,所设计的网络没有很好地嵌入该金属伪影移除(Metal Artifacts Reduction,MAR)任务特有的先验信息,网络模型的泛化能力有限。此外,这两个方案中包含的每个网络模块物理可解释性较弱,不易于本领域的技术人员理解和使用。The image processing method based on chord diagrams shown in FIGS. 2A and 2B can implement image processing for artifact removal as shown in FIGS. 1A and 1B . However, the common limitation of DuDoNet++ and DSCMAR is that in these two solutions, the chord diagram information used is difficult to obtain in practice and usually needs to be provided by the equipment manufacturer. Moreover, the designed network does not embed the prior information unique to the Metal Artifacts Reduction (MAR) task well, and the generalization ability of the network model is limited. In addition, each network module included in these two solutions has weak physical interpretability and is not easy to understand and use by those skilled in the art.
针对这些问题,本公开提出了一种用于伪影去除的图像处理方法,该方法可以只基于带伪影图像进行重构处理,克服了弦图数据获取困难的问题。而且本公开的图像处理方法利用特定的加权卷积字典模型来编码伪影的先验结构,使得网络更可靠,泛化能力更强。此外,本公开的自适应卷积字典网络模型具有清晰物理可解释性,易于本领域的技术人员理解和使用。In response to these problems, the present disclosure proposes an image processing method for artifact removal, which can perform reconstruction processing based only on images with artifacts, overcoming the problem of difficulty in obtaining chord diagram data. Moreover, the image processing method of the present disclosure uses a specific weighted convolution dictionary model to encode the prior structure of the artifact, making the network more reliable and with stronger generalization ability. In addition, the adaptive convolutional dictionary network model of the present disclosure has clear physical interpretability and is easy to understand and use by those skilled in the art.
图4为根据本公开实施例的基于加权自适应卷积字典的图像处理模型的示例性示意图。FIG. 4 is an exemplary schematic diagram of an image processing model based on a weighted adaptive convolution dictionary according to an embodiment of the present disclosure.
对于带金属伪影的CT图像,可以将其非金属区域分解为如下模型:
I⊙Y=I⊙X+I⊙A,   (1)
For CT images with metal artifacts, their non-metal regions can be decomposed into the following model:
I⊙Y=I⊙X+I⊙A, (1)
其中,是带金属伪影的CT图像;H和W分别为图像的高度和宽度;X是待复原的干净CT图像;I是非金属区域mask,其元素为{0,1},其中1表示非金属区域;A是金属伪影。根据本公开实施例,非金属区域mask I可以是已知的,其用于将求解的数学模型聚焦于非金属域,而不再关注金属域的求解。in, is the CT image with metal artifacts; H and W are the height and width of the image respectively; ;A is a metallic artifact. According to embodiments of the present disclosure, the non-metallic region mask I may be known, which is used to focus the solved mathematical model on the non-metallic domain and no longer pay attention to the solution of the metallic domain.
应了解,对于不同的带金属伪影的CT图像,其包含的金属伪影A基本呈现出共同或相似的模式,即形态类似的条状结构。同时,由于人体正常组织与金属伪影的互相影响,在不同的带金属伪影的CT图像中,其包含的伪影模式又具有一些特定的属性,比如像素强度。It should be understood that for different CT images with metal artifacts, the metal artifacts A contained therein basically show a common or similar pattern, that is, strip structures with similar shapes. At the same time, due to the interaction between normal human tissue and metal artifacts, the artifact patterns contained in different CT images with metal artifacts have some specific attributes, such as pixel intensity.
考虑带金属伪影的CT图像的上述特点,根据本公开实施例,对于每个待处理的带伪影图像(Y),通过利用预先从已有样本中学习得到的基本伪影字典来构建用于该图像的自适应卷积核并且提取该图像的伪影特征然后可以基于该图像的自适应卷积核与伪影特征得到该图像的金属伪影A,从而实现了金属伪影的提取。应理解,基本伪影字典既可以是现有已知的基本伪影字典,也可以是通过现有样本训练、合成而得到的基本伪影字典。Considering the above characteristics of CT images with metal artifacts, according to embodiments of the present disclosure, for each artifact image (Y) to be processed, by using a basic artifact dictionary learned in advance from existing samples to build an adaptive convolution kernel for the image And extract the artifact features of the image Then the adaptive convolution kernel based on this image can be with artifact features The metal artifact A of the image is obtained, thereby realizing the extraction of the metal artifact. It should be understood that the basic artifact dictionary It can be either an existing known basic artifact dictionary or a basic artifact dictionary obtained through training and synthesis of existing samples.
根据本公开实施例,可以采用加权的卷积字典模型对金属伪影A进行编码建模:
According to embodiments of the present disclosure, a weighted convolution dictionary model can be used to encode the metal artifact A:
其中,是一个样本不变的字典,包括了d个卷积核,代表了不同金属伪影的共同模式,简言之,代表所有带金属伪影的CT图像中不同金属伪影类型的共同数据库;是随着样本变化的加权系数;表示特定的卷积核,它代表了某一金属伪影重复出现的模式,p×p是卷积核尺寸大小;是特征层,代表局部模式重复出现的 位置;N是用来编码A所使用的真正的特定卷积核的数量;是二维平面卷积运算,p和d都为正整数。此外,并且
in, is a sample-invariant dictionary, including d convolution kernels, representing the common patterns of different metal artifacts. In short, A common database representing different metal artifact types in all CT images with metal artifacts; is the weighting coefficient that changes with the sample; Represents a specific convolution kernel, which represents a recurring pattern of a certain metal artifact, p×p is the size of the convolution kernel; is the feature layer, which represents the recurrence of local patterns. Position; N is the number of real specific convolution kernels used to encode A; It is a two-dimensional plane convolution operation, and p and d are both positive integers. also, and
即,基本伪影字典是不随样本变化的卷积字典并且包括第一数量(d)的伪影卷积核。通过基本伪影字典中的多个伪影卷积核与随样本变化的加权系数(K)可以确定用于图像样本的第二数量的自适应卷积核 That is, the basic artifact dictionary is a convolutional dictionary that does not change with samples and includes a first number (d) of artifact convolution kernels. The second number of adaptive convolution kernels for the image sample can be determined by a plurality of artifact convolution kernels in the basic artifact dictionary and a weighting coefficient (K) that changes with the sample.
将方程(2)带入方程(1),可以得到最终的带金属伪影的CT图像对应的非金属区域的模型为:
Putting equation (2) into equation (1), the model of the non-metallic area corresponding to the final CT image with metal artifacts can be obtained as:
图5A示出了根据本公开实施例的自适应卷积字典网络的示意性结构,其包括T级网络。在每级网络中,分别对加权系数K、特征层和干净CT图像X进行更新。图5B示出了根据本公开实施例的每级网络的示意性结构。FIG. 5A shows a schematic structure of an adaptive convolutional dictionary network according to an embodiment of the present disclosure, which includes a T-level network. In each level of network, the weighting coefficient K, feature layer and clean CT image X are updated. Figure 5B shows a schematic structure of a network at each level according to an embodiment of the present disclosure.
下面将首先结合图4、图5A和图5B来描述根据本公开实施例的图像处理方法,然后再描述图5A和图5B的自适应卷积字典网络的数学模型。The image processing method according to the embodiment of the present disclosure will first be described below in conjunction with Figures 4, 5A and 5B, and then the mathematical model of the adaptive convolutional dictionary network of Figures 5A and 5B will be described.
图3B是示出根据本公开的实施例的用于伪影去除的图像处理方法的模型使用过程的示意性流程图320。3B is a schematic flowchart 320 illustrating a model usage process of an image processing method for artifact removal according to an embodiment of the present disclosure.
在S321中,获取待处理的输入图像。In S321, the input image to be processed is obtained.
根据本公开实施例,待处理的输入图像可以是对原始的CT图像应用了其对应的图像掩膜(I)之后得到的图像,即I⊙Y。可选地,待处理的输入图像可以是带伪影的图像,也可以是经过预处理(例如,去噪处理、归一化处理)的带伪影的图像。需要说明的是,本公开中的图像掩膜(I)为待研究区或所关注区的掩膜。According to an embodiment of the present disclosure, the input image to be processed may be an image obtained after applying its corresponding image mask (I) to the original CT image, that is, I⊙Y. Optionally, the input image to be processed may be an image with artifacts, or may be an image with artifacts that has undergone preprocessing (eg, denoising processing, normalization processing). It should be noted that the image mask (I) in this disclosure is a mask of the area to be studied or the area of interest.
在S322中,利用自适应卷积字典网络,对所述输入图像进行处理,以得到去除伪影的处理后图像。In S322, the input image is processed using an adaptive convolutional dictionary network to obtain a processed image with artifacts removed.
其中,所述自适应卷积字典网络是基于伪影数据库(D)训练的,并且包括T级网络(如图5A所示),其中,第1级网络基于所述输入图像输出第1级图像特征和第1级伪影去除图像;第t级网络至少部分基于第t-1级网络输出的第t-1级图像特征和第t-1级伪影去除图像,输出第t级图像特征和第t级伪影去除图像,其中t大于1且小于等于T;第T级网络基于第T-1级网络输出的第T-1级图像特征和第T-1级伪影去除图像,输出第T级伪影去除图像作为所述去除伪影的处理后图像。该去除伪影的处理后图像可以通过显示器的方式输出也可以通过胶片、图纸等方式输出给用户。Wherein, the adaptive convolutional dictionary network is trained based on the artifact database (D) and includes a T-level network (as shown in Figure 5A), wherein the level 1 network outputs a level 1 image based on the input image Features and level 1 artifact removal images; the t-th level network is based at least in part on the t-1th level image features and the t-1th level artifact removal image output by the t-1th level network, and outputs the t-th level image features and The t-th level artifact removal image, where t is greater than 1 and less than or equal to T; the T-th level network outputs the T-1th level image feature and the T-1th level artifact removal image based on the T-1th level network output The T-level artifact removal image is used as the processed image after artifact removal. The processed image with artifacts removed can be output to the user through a display or through film, drawings, etc.
根据本公开实施例,所述自适应卷积字典网络包括基本伪影字典,所述基本伪影字典是不随输入图像变化的卷积字典并且包括伪影卷积核,在第t级网络中,首先确定第t级网络的第t级加权系数,接着通过所述基本伪影字典中的伪影卷积核与所述第t级加权系数来确定用于所述第t级网络的自适应卷积核;然后基于所述自适应卷积核与所述第t级网络的图像特 征确定第t级伪影去除图像。According to an embodiment of the present disclosure, the adaptive convolution dictionary network includes a basic artifact dictionary, which is a convolution dictionary that does not change with the input image and includes an artifact convolution kernel. In the t-th level network, First, determine the t-th level weighting coefficient of the t-th level network, and then determine the adaptive convolution for the t-th level network through the artifact convolution kernel in the basic artifact dictionary and the t-th level weighting coefficient. convolution kernel; then based on the adaptive convolution kernel and the image characteristics of the t-th level network Characteristics determine the t-th level artifact removal image.
伪影卷积核的数量可以记为第一数量,为大于1的整数值。本申请不限定自适应卷积核的数量,其数量可以记为第二数量。The number of artifact convolution kernels can be recorded as the first number, which is an integer value greater than 1. This application does not limit the number of adaptive convolution kernels, and their number can be recorded as the second number.
根据本公开实施例,每级网络可以包括加权系数更新网络、图像特征更新网络、及伪影去除图像更新网络,其中,加权系数更新网络、图像特征更新网络、及伪影去除图像更新网络包括残差网络结构及归一化处理层。应当理解,加权系数更新网络、图像特征更新网络、及伪影去除图像更新网络的网络结构可以是多样的,网络结构通常与该网络所对应的求解变量的维度特征有关。例如,加权系数更新网络求解变量为系数,所以通常包括线性层,而图像特征更新网络及伪影去除图像更新网络求解变量为二维图像,所以通常包括卷积层。According to an embodiment of the present disclosure, each level of the network may include a weighted coefficient update network, an image feature update network, and an artifact removal image update network, wherein the weighted coefficient update network, the image feature update network, and the artifact removal image update network include residual Differential network structure and normalization processing layer. It should be understood that the network structures of the weighted coefficient update network, image feature update network, and artifact removal image update network can be diverse, and the network structure is usually related to the dimensional characteristics of the solution variables corresponding to the network. For example, the weighted coefficient update network solves for coefficients, so it usually includes a linear layer, while the image feature update network and the artifact removal image update network solve for two-dimensional images, so it usually includes a convolutional layer.
根据本公开实施例,所述伪影图像可以为金属伪影,所述待处理的输入图像可以为带金属伪影的CT图像,所述图像掩膜(I)可以为与带金属伪影的CT图像对应的非金属区掩膜。在该实施例下,每级网络可以包括加权系数更新网络、金属伪影图像特征更新网络、及金属伪影去除图像更新网络,其中,加权系数更新网络、金属伪影图像特征更新网络、及金属伪影去除图像更新网络包括残差网络结构;并且加权系数更新网络包括:线性层、修正线性单元(Rectified Linear Unit,ReLU)层、跨链接层,及批标准化(Batch Normalization,BN)层;金属伪影图像特征更新网络包括:卷积层、BN层、ReLU层,及跨链接层;金属伪影去除图像更新网络包括:卷积层、BN层、ReLU层,及跨链接层。According to an embodiment of the present disclosure, the artifact image may be a metal artifact, the input image to be processed may be a CT image with metal artifacts, and the image mask (I) may be the same as a CT image with metal artifacts. Non-metal area mask corresponding to CT image. In this embodiment, each level of the network may include a weighted coefficient update network, a metal artifact image feature update network, and a metal artifact removal image update network, where the weighted coefficient update network, the metal artifact image feature update network, and the metal artifact removal image update network are The artifact removal image update network includes a residual network structure; and the weighted coefficient update network includes: a linear layer, a rectified linear unit (Rectified Linear Unit, ReLU) layer, a cross-link layer, and a batch normalization (Batch Normalization, BN) layer; metal The artifact image feature update network includes: convolution layer, BN layer, ReLU layer, and cross-link layer; the metal artifact removal image update network includes: convolution layer, BN layer, ReLU layer, and cross-link layer.
图3A是示出根据本公开的实施例的用于伪影去除的图像处理方法的神经网络训练过程的示意性流程图310。3A is a schematic flowchart 310 illustrating a neural network training process of an image processing method for artifact removal according to an embodiment of the present disclosure.
在S311中,建立用于训练神经网络的训练数据集,其中,所述训练数据集包括多组图像样本,每组图像样本包括带伪影图像(Y)及与其对应的无伪影图像(X)和图像掩膜(I)。In S311, a training data set for training the neural network is established, wherein the training data set includes multiple groups of image samples, each group of image samples includes an image with artifacts (Y) and its corresponding image without artifacts. (X) and image mask (I).
根据本公开实施例,可以使用公开的图像库以及不同类型的金属掩膜(mask),根据数据仿真流程合成伪影,并将带伪影图像和与该带伪影图像对应的金属掩膜(Me)作为训练数据。例如,在针对带金属伪影的CT图像去伪影的应用场景下,可以使用公开的DeepLesion图像库以及不同类型的金属mask,根据数据仿真流程合成金属伪影,并将带金属伪影的CT图像和金属mask作为训练数据。应了解,所述不同类型的掩膜(mask)或不同类型的金属mask,用于设定CT图像中植入物的尺寸及形状,可以基于植入物的尺寸及形状,仿真得到其对应的伪影形状。金属掩膜(Me)与非金属区掩膜(I)存在对应关系,可以互相推导,即Me+I=1。According to embodiments of the present disclosure, public image libraries and different types of metal masks can be used to synthesize artifacts according to the data simulation process, and the artifact-bearing image and the metal mask corresponding to the artifact-bearing image ( Me ) as training data. For example, in the application scenario of removing artifacts from CT images with metal artifacts, you can use the public DeepLesion image library and different types of metal masks to synthesize metal artifacts according to the data simulation process, and convert the CT images with metal artifacts into Images and metal masks are used as training data. It should be understood that the different types of masks or different types of metal masks are used to set the size and shape of the implant in the CT image. Based on the size and shape of the implant, the corresponding simulation can be obtained. Artifact shape. There is a corresponding relationship between the metal mask (M e ) and the non-metal area mask (I), and they can be deduced from each other, that is, Me + I = 1.
根据本公开实施例,为了处理更大数据范围的样本数据,所述建立用于训练神经网络的训练数据集可以包括:对所述带伪影图像(Y)的像素值进行归一化处理。According to an embodiment of the present disclosure, in order to process sample data of a larger data range, establishing a training data set for training a neural network may include: normalizing the pixel values of the image with artifacts (Y).
此外,为了获得样本数据的多样性,所述建立用于训练神经网络的训练数据集可以包括:对所述带伪影图像(Y)进行随机裁剪以获得图像块,并按照预定的概率对所述图像块进行随机翻转处理。In addition, in order to obtain the diversity of sample data, the establishment of a training data set for training a neural network may include: randomly cropping the artifact-bearing image (Y) to obtain image blocks, and classifying all the artifacts according to a predetermined probability. The above image blocks are randomly flipped.
例如,可以将训练数据中带伪影的图像的数值范围进行裁剪(比如,去除数值太大的值或负值,使得不需要的数值范围不再被保留,但不会丢失需要的组织信息),然后做归一 化处理使得图像的像素值处于阈值[0,1]范围内。可选地,还可以将归一化处理后的数据再转换到[0,255]范围以方便计算机处理。For example, you can crop the numerical range of images with artifacts in the training data (for example, remove values that are too large or negative values, so that unnecessary numerical ranges are no longer retained, but the required organizational information will not be lost) , and then normalize The pixel value of the image is within the threshold range [0,1]. Optionally, the normalized data can also be converted to the [0,255] range to facilitate computer processing.
根据本公开的实施例,还可以将每张训练图像以及对应的mask进行随机裁剪以形成较小的图像块(例如,可以是64x64像素大小的图像块),然后以预定概率(例如,可以是0.5)分别进行随机水平镜像翻转和随机垂直镜像翻转,以获得更加多样化的训练样本数据。According to embodiments of the present disclosure, each training image and the corresponding mask can also be randomly cropped to form a smaller image block (for example, it can be an image block of 64x64 pixel size), and then with a predetermined probability (for example, it can be 0.5) Perform random horizontal mirror flipping and random vertical mirror flipping respectively to obtain more diverse training sample data.
对于所述多组图像样本中的任意一组图像样本,均可以通过执行下述S312-S313来实现对自适应卷积字典网络的网络参数的优化。For any group of image samples among the plurality of groups of image samples, optimization of the network parameters of the adaptive convolutional dictionary network can be achieved by executing the following S312-S313.
在S312中,利用自适应卷积字典网络,对所述带伪影图像(Y)进行伪影去除处理,以得到处理后图像。In S312, an adaptive convolutional dictionary network is used to perform artifact removal processing on the image with artifacts (Y) to obtain a processed image.
根据本公开实施例,如图4所示,所述自适应卷积字典网络可以包括基本伪影字典,所述基本伪影字典是不随样本变化的卷积字典并且包括伪影卷积核,可以通过所述基本伪影字典中的多个伪影卷积核与随样本变化的加权系数来确定用于所述图像样本的自适应卷积核。而且,可以通过所述自适应卷积核与所述带伪影图像的图像特征的卷积来确定所述带伪影图像中的伪影图像,并从所述带伪影图像中去除所述伪影图像以得到所述处理后图像。According to an embodiment of the present disclosure, as shown in Figure 4, the adaptive convolution dictionary network may include a basic artifact dictionary, which is a convolution dictionary that does not change with samples and includes an artifact convolution kernel, and may The adaptive convolution kernel for the image sample is determined through a plurality of artifact convolution kernels in the basic artifact dictionary and a weighting coefficient that changes with the sample. Furthermore, the artifact image in the artifact-bearing image can be determined by convolving the adaptive convolution kernel with the image features of the artifact-bearing image, and the artifact-bearing image can be removed from the artifact-bearing image. Artifact image to obtain the processed image.
在S313中,基于所述无伪影图像(X)和所述处理后图像、以及经所述图像掩膜(I)处理的目标函数对所述自适应卷积字典网络进行迭代训练,以优化所述自适应卷积字典网络的网络参数。In S313, the adaptive convolutional dictionary network is iteratively trained based on the artifact-free image (X), the processed image, and the objective function processed by the image mask (I) to optimize Network parameters of the adaptive convolutional dictionary network.
根据本公开实施例,所述目标函数可以为基于所述无伪影图像(X)和所述处理后图像所构建的损失目标函数,其中,所述基于所述无伪影图像(X)和所述处理后图像、以及目标函数对所述自适应卷积字典网络进行迭代训练,以优化所述自适应卷积字典网络的网络参数包括:计算损失目标函数并将其结果反向传播到所述自适应卷积字典网络,并基于自适应矩估计(Adaptive moment estimation,Adam)算法优化所述自适应卷积字典网络的网络参数。According to an embodiment of the present disclosure, the objective function may be a loss objective function constructed based on the artifact-free image (X) and the processed image, wherein the objective function is constructed based on the artifact-free image (X) and the processed image. The processed image and the objective function are used to iteratively train the adaptive convolutional dictionary network to optimize the network parameters of the adaptive convolutional dictionary network, including: calculating the loss objective function and backpropagating the result to the adaptive convolutional dictionary network. The adaptive convolutional dictionary network is described, and the network parameters of the adaptive convolutional dictionary network are optimized based on the adaptive moment estimation (Adaptive moment estimation, Adam) algorithm.
根据本公开实施例,所述目标函数还可以为基于所述无伪影图像(X)和所述处理后图像所构建的并经图像掩膜(I)处理后的损失目标函数。According to an embodiment of the present disclosure, the objective function may also be a loss objective function constructed based on the artifact-free image (X) and the processed image and processed by the image mask (I).
根据本公开实施例,所述伪影卷积核指示伪影模式,所述图像特征指示所述伪影模式所在的位置,其中,所述自适应卷积字典网络包括T级网络,其中,在第t级网络中,利用基于近端梯度下降的迭代更新规则对第t-1级网络输出的加权系数和图像特征进行更新,以得到第t级网络的加权系数和图像特征,其中t为大于1且小于等于T的整数。According to an embodiment of the present disclosure, the artifact convolution kernel indicates an artifact pattern, and the image feature indicates the location of the artifact pattern, wherein the adaptive convolution dictionary network includes a T-level network, wherein In the t-level network, the iterative update rule based on proximal gradient descent is used to update the weighted coefficients and image features output by the t-1 level network to obtain the weighted coefficients and image features of the t-level network, where t is greater than An integer that is 1 and less than or equal to T.
根据本公开实施例,每级网络可以包括加权系数更新网络、图像特征更新网络、及伪影去除图像更新网络,其中,加权系数更新网络、图像特征更新网络、及伪影去除图像更新网络包括残差网络结构及归一化处理层。应当理解,加权系数更新网络、图像特征更新网络、及伪影去除图像更新网络的网络结构可以是多样的,网络结构通常与该网络所对应的求解变量的维度特征有关。例如,加权系数更新网络求解变量为系数,所以通常包括线性层,而图像特征更新网络及伪影去除图像更新网络求解变量为二维图像,所以通常包括卷积层。According to an embodiment of the present disclosure, each level of the network may include a weighted coefficient update network, an image feature update network, and an artifact removal image update network, wherein the weighted coefficient update network, the image feature update network, and the artifact removal image update network include residual Differential network structure and normalization processing layer. It should be understood that the network structures of the weighted coefficient update network, image feature update network, and artifact removal image update network can be diverse, and the network structure is usually related to the dimensional characteristics of the solution variables corresponding to the network. For example, the weighted coefficient update network solves for coefficients, so it usually includes a linear layer, while the image feature update network and the artifact removal image update network solve for two-dimensional images, so it usually includes a convolutional layer.
根据本公开实施例,用于伪影去除的图像处理方法还可以包括:在训练完成后,对所 述自适应卷积字典网络进行测试,以评估图像处理的效果。其中,所述对所述自适应卷积字典网络进行测试包括:对待测试的带伪影图像进行预处理,并输入到所述自适应卷积字典网络;利用自适应卷积字典网络,对所述待测试的带伪影图像进行处理,以得到去除伪影的处理后图像。According to embodiments of the present disclosure, the image processing method for artifact removal may further include: after the training is completed, The adaptive convolutional dictionary network was tested to evaluate the effect of image processing. Wherein, testing the adaptive convolutional dictionary network includes: preprocessing the artifact-bearing image to be tested and inputting it into the adaptive convolutional dictionary network; using the adaptive convolutional dictionary network to The image with artifacts to be tested is processed to obtain a processed image with artifacts removed.
根据本公开的实施例,所述伪影图像可以为金属伪影,所述带伪影图像可以为带金属伪影的CT图像。因此,所述训练数据集包括多组CT图像样本,每组图像样本包括带金属伪影的CT图像及与其对应的无金属伪影的CT图像;所述自适应卷积字典网络包括基本金属伪影字典,所述基本金属伪影字典是不随CT图像样本变化的金属伪影卷积字典并且包括金属伪影卷积核,并且通过所述基本金属伪影字典中的多个金属伪影卷积核与随CT图像样本变化的加权系数来确定用于所述CT图像样本的自适应卷积核,其中,所述金属伪影卷积核指示金属伪影模式,所述图像特征指示所述金属伪影模式所在的位置。According to an embodiment of the present disclosure, the artifact image may be a metal artifact, and the image with artifacts may be a CT image with metal artifacts. Therefore, the training data set includes multiple groups of CT image samples, each group of image samples includes CT images with metal artifacts and corresponding CT images without metal artifacts; the adaptive convolution dictionary network includes basic metal Artifact dictionary, the basic metal artifact dictionary is a metal artifact convolution dictionary that does not change with CT image samples and includes a metal artifact convolution kernel, and is passed through a plurality of metal artifact volumes in the basic metal artifact dictionary The adaptive convolution kernel for the CT image sample is determined with a weighting coefficient that changes with the CT image sample, wherein the metal artifact convolution kernel indicates a metal artifact pattern, and the image feature indicates the Where the metal artifact pattern is located.
根据本公开实施例,在针对CT图像去除伪影的应用场景下,每级网络可以包括加权系数更新网络、金属伪影图像特征更新网络、及金属伪影去除图像更新网络,其中,加权系数更新网络、金属伪影图像特征更新网络、及金属伪影去除图像更新网络包括残差网络结构;并且加权系数更新网络包括:线性层、ReLU层、跨链接层,及BN层;金属伪影图像特征更新网络包括:卷积层、BN层、ReLU层,及跨链接层;金属伪影去除图像更新网络包括:卷积层、BN层、ReLU层,及跨链接层。According to embodiments of the present disclosure, in the application scenario of removing artifacts from CT images, each level of the network may include a weighted coefficient update network, a metal artifact image feature update network, and a metal artifact removal image update network, where the weighted coefficient update network The network, the metal artifact image feature update network, and the metal artifact removal image update network include a residual network structure; and the weighted coefficient update network includes: a linear layer, a ReLU layer, a cross-link layer, and a BN layer; metal artifact image features The update network includes: convolution layer, BN layer, ReLU layer, and cross-link layer; the metal artifact removal image update network includes: convolution layer, BN layer, ReLU layer, and cross-link layer.
下面继续以图4中对带金属伪影的CT图像的去除金属伪影的数学模型作为示例,参考图4、5A和图5B来描述具体地阐述本公开所述的用于伪影去除的图像处理方法的数学模型和自适应卷积字典网络的结构。The following continues to take the mathematical model for removing metal artifacts from CT images with metal artifacts in Figure 4 as an example. The image used for artifact removal according to the present disclosure will be described in detail with reference to Figures 4, 5A and 5B. Mathematical model of the processing method and structure of the adaptive convolutional dictionary network.
根据本公开实施例,可以将代表所有带金属伪影的CT图像中不同金属伪影类型的共同数据库的构建为一个卷积层,基于此构建出自适应卷积字典网络,并且通过训练数据集端到端训练得到自适应卷积字典网络的优化参数。According to embodiments of the present disclosure, a common database representing different metal artifact types in all CT images with metal artifacts can be It is constructed as a convolution layer, based on which an adaptive convolutional dictionary network is constructed, and the optimized parameters of the adaptive convolutional dictionary network are obtained through end-to-end training on the training data set.
对于以上方程(4)所示的数学模型:
For the mathematical model shown in equation (4) above:
其求解目标为从Y中估计出K,和X,其对应的优化问题为:
The solution goal is to estimate K from Y, and X, the corresponding optimization problem is:
其中,α、β和γ为折衷参数,f1(·)、f2(·)和f3(·)均为正则项,分别代表加权系数K、特征层和干净CT图像X的先验结构,可以将其设计为神经网络模块以进行求解。Among them, α, β and γ are compromise parameters, f 1 (·), f 2 (·) and f 3 (·) are regular terms, which respectively represent the weighting coefficient K, feature layer and the prior structure of the clean CT image X, which can be designed as a neural network module to solve.
为求解(5)中的优化问题,可以采用近端梯度技术来交替更新加权系数K、特征层 和干净CT图像X。具体如下:In order to solve the optimization problem in (5), proximal gradient technology can be used to alternately update the weighting coefficient K and the feature layer and clean CT image X. details as follows:
更新K:Update K:
在第(t+1)次迭代中,K可以被更新为:
In the (t+1)th iteration, K can be updated as:
其对应的二次近似形式为:
The corresponding quadratic approximation form is:
其中,Ω={K|‖Kn2=1,n=1,2,…,N}; η1为更新步长,可以推导得到:
Among them, Ω={K|‖K n2 =1,n=1,2,…,N}; η 1 is the update step size, which can be derived:
其中,为深度卷积操作;表示在第3个维度对张量进行展开;vec(·)表示向量化操作。in, For depth convolution operation; Represents the expansion of the tensor in the third dimension; vec(·) represents the vectorization operation.
方程(7)可以等价写为:
Equation (7) can be equivalently written as:
对于一般的先验项f1(·),方程(9)可以写为:
For the general prior term f 1 (·), equation (9) can be written as:
其中,
in,
是近端算子,与正则项f1(·)有关;Ω可以通过对引入一个归一化操作来实现。 is a proximal operator, related to the regular term f 1 (·); Ω can be obtained by Introduce a normalization operation to achieve this.
更新 renew
与N的更新类似,在第(t+1)次迭代中,可以被更新为:
Similar to the update of N, in the (t+1)th iteration, can be updated to:
其中,η2为更新步长,对于一般的先验项f2(·),方程(11)可以写为:
Among them, eta 2 is the update step size, For the general prior term f 2 (·), equation (11) can be written as:
其中,是近端算子,与正则项f2(·)有关; 为转置卷积运算。in, is a proximal operator, related to the regular term f 2 (·); is the transposed convolution operation.
更新X: UpdateX:
给定N(t+1) 可以被更新为:
Given N (t+1) and can be updated to:
其中,进一步地,可以得到X的更新规则为:
in, Further, the update rule of X can be obtained as:
其中, 是近端算子,与正则项f3(·)有关。in, is a proximal operator, related to the regular term f 3 (·).
通过将更新公式(10)(12)(14)进行展开,最终可以构建出完整的自适应卷积字典网络(Adaptive Convolutional Dictionary Network,ACDNet),其中,各网络具有良好的物理解释性。By expanding the update formulas (10) (12) (14), a complete adaptive convolutional dictionary network (Adaptive Convolutional Dictionary Network, ACDNet) can finally be constructed, in which each network has good physical interpretability.
在图5A中示出了根据本公开实施例的自适应卷积字典网络的示意性结构,其包括T级网络。在每级网络中,分别对加权系数K、特征层和经处理的CT图像X进行更新。在图5B中示出了根据本公开实施例的每级网络的示意性结构。A schematic structure of an adaptive convolutional dictionary network according to an embodiment of the present disclosure is shown in FIG. 5A , which includes a T-level network. In each level of network, the weighting coefficient K, feature layer and processed CT image X are updated. A schematic structure of each level network according to an embodiment of the present disclosure is shown in Figure 5B.
根据本公开实施例,如图5A所示的ACDNet由T个阶段(即T级网络)构成,在每个阶段,对应的网络结构依次由K-net、和X-net构成,其分别用于实现K、和X的迭代更新。According to the embodiment of the present disclosure, ACDNet as shown in Figure 5A is composed of T stages (i.e., T-level network). In each stage, the corresponding network structure consists of K-net, and X-net, which are used to implement K, and iterative updates of X.
下面,解释图5A和图5B中网络结构与上述数学模型之间的对应关系。Next, the correspondence between the network structure in Figures 5A and 5B and the above mathematical model is explained.
在图5A和图5B中,具体地,In Figure 5A and Figure 5B, specifically,
K-net:其中是一个残差结构,具体为:线性层、ReLU层、线性层、跨链接层以及在维度d处的归一化操作层;K-net: in It is a residual structure, specifically: linear layer, ReLU layer, linear layer, cross-link layer and normalization operation layer at dimension d;
其中由3个残差块构成,每个残差块依次包括:卷积层,BN层,ReLU层,卷积层,BN层,以及跨链接层; in Composed of 3 residual blocks, each residual block includes in turn: convolution layer, BN layer, ReLU layer, convolution layer, BN layer, and cross-link layer;
X-net:其中由3个残差块构成,每个残差块依次包括:卷积层,BN层,ReLU层,卷积层,BN层,以及跨链接层。X-net: in It is composed of 3 residual blocks, and each residual block includes in turn: convolution layer, BN layer, ReLU layer, convolution layer, BN layer, and cross-link layer.
由图5A可以看出,第1级网络基于输入图像得到该第1级网络输出的第1级图像特征M(1)和第1级伪影去除图像X(1);第t级网络至少部分基于第t-1级网络的输出的第t-1级图像特征M(t-1)和第t-1级伪影去除图像X(t-1),得到并输出该第t级网络输出的第t级图像特征M(t)和第t级伪影去除图像X(t),其中t大于1且小于等于T;第T级网络基于第T-1级网络输出的第T-1级图像特征M(T-1)和第T-1级伪影去除图像X(T-1),得到并输出该第T级网络输出的第T级伪影去除图像X(T)作为所述去除伪影的处理后图像。As can be seen from Figure 5A, the first-level network obtains the first-level image feature M (1) and the first-level artifact removal image X (1) output by the first-level network based on the input image; the t-level network at least partially Based on the t-1th level image feature M (t-1) output by the t-1th level network and the t-1th level artifact removal image X (t-1) , obtain and output the t-th level network output The t-th level image feature M (t) and the t-th level artifact removal image X (t) , where t is greater than 1 and less than or equal to T; the T-th level network is based on the T-1 level image output by the T-1 level network Feature M (T-1) and T-1th level artifact removal image X (T-1) , obtain and output the Tth level artifact removal image X (T) output by the Tth level network as the artifact removal image The processed image of the shadow.
对于自适应卷积字典网络中的每级网络,其迭代求解过程如图5B所示。其中,在第t级网络中,利用基于近端梯度下降的迭代更新规则对第t-1级网络输出的加权系数和图像特征进行更新,以得到第t级网络的加权系数和图像特征,其中t为大于1且小于等于T的整数。 K-net,M-net,X-net按照串行的方式依次迭代求解。For each level of network in the adaptive convolutional dictionary network, the iterative solution process is shown in Figure 5B. Among them, in the t-th level network, the weighted coefficients and image features output by the t-1 level network are updated using the iterative update rule based on proximal gradient descent to obtain the weighting coefficients and image features of the t-level network, where t is an integer greater than 1 and less than or equal to T. K-net, M-net, and X-net are solved iteratively in a serial manner.
对于自适应卷积字典网络可以基于无伪影图像(X)和处理后图像、以及经图像掩膜(I)处理的目标函数来进行迭代训练,以优化所述自适应卷积字典网络的网络参数。其中,目标函数可以为基于所述无伪影图像(X)和所述处理后图像所构建的损失目标函数,即
The adaptive convolutional dictionary network can be iteratively trained based on the artifact-free image (X), the processed image, and the objective function processed by the image mask (I) to optimize the network of the adaptive convolutional dictionary network. parameter. Wherein, the objective function may be a loss objective function constructed based on the artifact-free image (X) and the processed image, that is,
其中,μt为折衷参数,ω1和ω2是用来平衡各项损失的权重。例如,在仿真实验中,可以设置μt=0.1(t=0,1,…,T-1),μT=1,ω1=ω2=5×10-4,T=10。Among them, μ t is the compromise parameter, and ω 1 and ω 2 are the weights used to balance various losses. For example, in the simulation experiment, μ t =0.1 (t = 0, 1,..., T-1), μ T =1, ω 12 =5×10 -4 , and T = 10 can be set.
根据本公开的实施例,可以采用基于Adam算法更新求解优化参数,包括,卷积核步长η1、η2和η3。在每次迭代过程中,计算预测结果误差并反向传播到卷积神经网络模型,计算梯度并更新卷积神经网络模型的参数。According to embodiments of the present disclosure, the optimization parameters can be updated and solved based on the Adam algorithm, including: Convolution kernel Step sizes eta 1 , eta 2 and eta 3 . During each iteration, the prediction result error is calculated and back-propagated to the convolutional neural network model, the gradient is calculated and the parameters of the convolutional neural network model are updated.
图6是示出根据本公开的实施例的用于伪影去除的图像处理过程的示意性流程图。FIG. 6 is a schematic flowchart illustrating an image processing process for artifact removal according to an embodiment of the present disclosure.
如图6所示,根据本公开的实施例的用于伪影去除的图像处理过程包括神经网络训练阶段和测试阶段。As shown in FIG. 6 , the image processing process for artifact removal according to an embodiment of the present disclosure includes a neural network training phase and a testing phase.
在神经网络训练阶段可以首先对带伪影的图像进行预处理,以建立用于训练神经网络的训练数据集,其中,所述训练数据集包括多组图像样本,每组图像样本包括带伪影图像(Y)及与其对应的无伪影图像(X)和图像掩膜(I)。然后基于预处理后的图像样本,计算机根据神经网络训练的设置来迭代训练ACDNet,其中,在训练过程中,ACDNet的参数是基于预定目标函数和Adam优化算法来更新的。如果在训练过程中达到了预定的迭代次数则保存训练的模型,如果未达到预定的迭代次数则继续训练ACDNet。In the neural network training stage, images with artifacts can first be preprocessed to establish a training data set for training the neural network, where the training data set includes multiple groups of image samples, and each group of image samples includes Artifact image (Y) and its corresponding artifact-free image (X) and image mask (I). Then based on the preprocessed image samples, the computer iteratively trains ACDNet according to the neural network training settings. During the training process, the parameters of ACDNet are updated based on the predetermined objective function and the Adam optimization algorithm. If the predetermined number of iterations is reached during the training process, the trained model is saved. If the predetermined number of iterations is not reached, ACDNet continues to be trained.
应当理解,这里采用达到预定的迭代次数来作为判断ACDNet训练完成的判据是为了防止网络过拟合。可选地,还可以以可视化的方式输出优化的图像,再确认经优化的图像满足需求后即停止继续训练ACDNet。It should be understood that the purpose of using the predetermined number of iterations as the criterion for judging the completion of ACDNet training is to prevent the network from overfitting. Optionally, you can also output the optimized image in a visual way, and then stop training ACDNet after confirming that the optimized image meets the requirements.
在测试阶段,将待处理的输入图像及与其对应的图像掩膜(I)输入给计算机,计算机加载经训练的模型,并通过ACDNet前向计算得到去除伪影后的图像,计算机可以输出去除伪影后的图像供用户参考。In the testing phase, the input image to be processed and its corresponding image mask (I) are input to the computer. The computer loads the trained model and obtains the artifact-removed image through ACDNet forward calculation. The computer can output the artifact-removed image. The post-production images are for user reference.
类似地,在实际使用过程中,图像处理过程与测试阶段类似,因此不再赘述。Similarly, in actual use, the image processing process is similar to the testing stage, so no details will be given.
图7A是示出根据本公开的实施例的用于伪影去除的图像处理装置的组成示意图710,该装置710用于图像处理时的神经网络训练过程。FIG. 7A is a schematic diagram 710 showing the composition of an image processing device for artifact removal according to an embodiment of the present disclosure. The device 710 is used for a neural network training process during image processing.
根据本公开的实施例,用于伪影去除的图像处理装置710可以包括:训练数据集建立模块711、自适应卷积字典网络712和训练模块713。According to an embodiment of the present disclosure, the image processing device 710 for artifact removal may include: a training data set establishment module 711, an adaptive convolutional dictionary network 712, and a training module 713.
其中,训练数据集建立模块711可以被配置为:建立用于训练神经网络的训练数据集,其中,所述训练数据集包括多组图像样本,每组图像样本包括带伪影图像(Y)及与其对应的无伪影图像(X)和图像掩膜(I)。Wherein, the training data set establishment module 711 can be configured to: establish a training data set for training the neural network, wherein the training data set includes multiple groups of image samples, and each group of image samples includes images with artifacts (Y ) and its corresponding artifact-free image (X) and image mask (I).
可选地,训练数据集建立模块711可以被配置为:对所述带伪影图像(Y)的像素值进 行归一化处理;和\或,对所述带伪影图像(Y)进行随机裁剪以获得图像块,并按照预定的概率对所述图像块进行随机翻转处理。Optionally, the training data set establishment module 711 may be configured to: perform pixel values of the image with artifacts (Y). Perform normalization processing; and\or, randomly crop the image with artifacts (Y) to obtain image blocks, and perform random flip processing on the image blocks according to a predetermined probability.
自适应卷积字典网络712可以被配置为:对于所述多组图像样本中的至少一组图像样本,对所述带伪影图像(Y)进行伪影去除处理,以得到处理后图像。The adaptive convolutional dictionary network 712 may be configured to: perform artifact removal processing on the artifact-bearing image (Y) for at least one group of image samples among the plurality of groups of image samples to obtain a processed image. .
所述自适应卷积字典网络712可以包括基本伪影字典,所述基本伪影字典是不随样本变化的卷积字典并且包括伪影卷积核,可以通过所述基本伪影字典中的多个伪影卷积核与随样本变化的加权系数来确定用于所述图像样本的自适应卷积核。而且,可以通过所述自适应卷积核与所述带伪影图像的图像特征的卷积来确定所述带伪影图像中的伪影图像,并从所述带伪影图像中去除所述伪影图像以得到所述处理后图像。The adaptive convolution dictionary network 712 may include a basic artifact dictionary, which is a convolution dictionary that does not change with samples and includes an artifact convolution kernel. The artifact convolution kernel and the weighting coefficient that change with the sample are used to determine the adaptive convolution kernel for the image sample. Furthermore, the artifact image in the artifact-bearing image can be determined by convolving the adaptive convolution kernel with the image features of the artifact-bearing image, and the artifact-bearing image can be removed from the artifact-bearing image. Artifact image to obtain the processed image.
训练模块713可以被配置为:基于所述无伪影图像(X)和所述处理后图像、以及经所述图像掩膜(I)处理的目标函数对所述自适应卷积字典网络进行迭代训练,以优化所述自适应卷积字典网络的网络参数。The training module 713 may be configured to iterate the adaptive convolutional dictionary network based on the artifact-free image (X) and the processed image, and an objective function processed by the image mask (I) Train to optimize the network parameters of the adaptive convolutional dictionary network.
根据本公开实施例,所述目标函数可以为基于所述无伪影图像(X)和所述处理后图像所构建的损失目标函数,其中,训练模块713可以被配置为:计算损失目标函数并将其结果反向传播到所述自适应卷积字典网络,并基于Adam算法优化所述自适应卷积字典网络的网络参数。According to an embodiment of the present disclosure, the objective function may be a loss objective function constructed based on the artifact-free image (X) and the processed image, wherein the training module 713 may be configured to: calculate the loss objective function and The results are backpropagated to the adaptive convolutional dictionary network, and the network parameters of the adaptive convolutional dictionary network are optimized based on the Adam algorithm.
根据本公开实施例,所述伪影卷积核指示伪影模式,所述图像特征指示所述伪影模式所在的位置,其中,所述自适应卷积字典网络包括T级网络,其中,在第t级网络中,利用基于近端梯度下降的迭代更新规则对第t-1级网络输出的加权系数和图像特征进行更新,以得到第t级网络的加权系数和图像特征,其中t为大于1且小于等于T的整数According to an embodiment of the present disclosure, the artifact convolution kernel indicates an artifact pattern, and the image feature indicates the location of the artifact pattern, wherein the adaptive convolution dictionary network includes a T-level network, wherein In the t-level network, the iterative update rule based on proximal gradient descent is used to update the weighted coefficients and image features output by the t-1 level network to obtain the weighted coefficients and image features of the t-level network, where t is greater than An integer that is 1 and less than or equal to T
根据本公开实施例,每级网络包括加权系数更新网络、图像特征更新网络、及伪影去除图像更新网络,其中,加权系数更新网络、图像特征更新网络、及伪影去除图像更新网络包括残差网络结构及归一化处理层。According to an embodiment of the present disclosure, each level of the network includes a weighted coefficient update network, an image feature update network, and an artifact removal image update network, wherein the weighted coefficient update network, the image feature update network, and the artifact removal image update network include residual Network structure and normalization processing layer.
根据本公开实施例,用于伪影去除的图像处理装置710还可以包括:测试模块714,被配置为:在训练完成后,对所述自适应卷积字典网络进行测试,其中,所述对所述自适应卷积字典网络进行测试包括:对待测试的带伪影图像进行预处理,并输入到所述自适应卷积字典网络;利用自适应卷积字典网络,对所述待测试的带伪影图像进行处理,以得到去除伪影的处理后图像。According to an embodiment of the present disclosure, the image processing device 710 for artifact removal may further include: a testing module 714 configured to: test the adaptive convolutional dictionary network after the training is completed, wherein the Testing the adaptive convolutional dictionary network includes: preprocessing the artifact-containing image to be tested and inputting it into the adaptive convolutional dictionary network; using the adaptive convolutional dictionary network to preprocess the artifact-containing image to be tested. Artifact images are processed to obtain a processed image with artifacts removed.
图7B是示出根据本公开的实施例的用于伪影去除的图像处理装置的组成示意图720,该装置720用于图像处理时的模型使用过程。FIG. 7B is a schematic diagram 720 showing the composition of an image processing device for artifact removal according to an embodiment of the present disclosure. The device 720 is used in a model usage process during image processing.
根据本公开的实施例,用于伪影去除的图像处理装置720可以包括:图像获取模块721、图像处理模块722。According to an embodiment of the present disclosure, the image processing device 720 for artifact removal may include: an image acquisition module 721 and an image processing module 722.
其中,图像获取模块721可以被配置为:获取待处理的输入图像。Wherein, the image acquisition module 721 may be configured to: acquire the input image to be processed.
根据本公开实施例,待处理的输入图像可以是对原始的CT图像应用于了其对应的图像掩膜之后得到的图像。例如,图像获取模块721可以接收原始CT图像以及与其对应的图像掩膜,并对原始的CT图像应用于了其对应的图像掩膜,从而获取到待处理的输入图像。According to embodiments of the present disclosure, the input image to be processed may be an image obtained after applying its corresponding image mask to the original CT image. For example, the image acquisition module 721 may receive the original CT image and its corresponding image mask, and apply its corresponding image mask to the original CT image, thereby acquiring the input image to be processed.
根据本公开实施例,待处理的输入图像可以是带伪影的图像,也可以是经过预处理(例 如,去噪处理、归一化处理)的带伪影的图像。According to embodiments of the present disclosure, the input image to be processed may be an image with artifacts, or may be a pre-processed image (for example Such as denoising processing, normalization processing) images with artifacts.
图像处理模块722可以被配置为:利用自适应卷积字典网络,对所述输入图像进行处理,以得到去除伪影的处理后图像。The image processing module 722 may be configured to use an adaptive convolutional dictionary network to process the input image to obtain a processed image with artifacts removed.
其中,所述自适应卷积字典网络是基于伪影数据库(D)训练的,并且包括T级网络,其中,第1级网络基于所述输入图像输出第1级图像特征和第1级伪影去除图像;第t级网络至少部分基于第t-1级网络输出的第t-1级图像特征和第t-1级伪影去除图像,输出第t级图像特征和第t级伪影去除图像,其中t大于1且小于等于T;第T级网络基于第T-1级网络输出的第T-1级图像特征和第T-1级伪影去除图像,输出第T级伪影去除图像作为所述去除伪影的处理后图像。Wherein, the adaptive convolutional dictionary network is trained based on the artifact database (D) and includes a T-level network, wherein the level 1 network outputs level 1 image features and level 1 artifacts based on the input image. Remove the image; the t-th level network outputs the t-level image features and the t-th level artifact removal image based at least in part on the t-1 level image features and the t-1 level artifact removal image output by the t-1 level network. , where t is greater than 1 and less than or equal to T; the T-level network is based on the T-1-th level image features and the T-1-th level artifact removal image output by the T-1-th level network, and outputs the T-th level artifact removal image as The processed image after artifact removal.
根据本公开实施例,所述自适应卷积字典网络包括基本伪影字典,所述基本伪影字典是不随输入图像变化的卷积字典并且包括伪影卷积核,确定第t级网络的第t级加权系数,通过所述基本伪影字典中的多个伪影卷积核与所述第t级加权系数来确定用于所述第t级网络的自适应卷积核;并且基于所述自适应卷积核与所述第t级网络的图像特征确定第t级伪影去除图像。According to an embodiment of the present disclosure, the adaptive convolution dictionary network includes a basic artifact dictionary, which is a convolution dictionary that does not change with the input image and includes an artifact convolution kernel, which determines the t-th level network The t-level weighting coefficient determines the adaptive convolution kernel for the t-th level network through multiple artifact convolution kernels in the basic artifact dictionary and the t-th level weighting coefficient; and based on the The adaptive convolution kernel and the image features of the t-th level network determine the t-th level artifact removal image.
一般而言,本公开的各种示例实施例可以在硬件或专用电路、软件、固件、逻辑,或其任何组合中实施。某些方面可以在硬件中实施,而其他方面可以在可以由控制器、微处理器或其他计算设备执行的固件或软件中实施。当本公开的实施例的各方面被图示或描述为框图、流程图或使用某些其他图形表示时,将理解此处描述的方框、装置、系统、技术或方法可以作为非限制性的示例在硬件、软件、固件、专用电路或逻辑、通用硬件或控制器或其他计算设备,或其某些组合中实施。Generally speaking, the various example embodiments of the present disclosure may be implemented in hardware or special purpose circuits, software, firmware, logic, or any combination thereof. Some aspects may be implemented in hardware, while other aspects may be implemented in firmware or software that may be executed by a controller, microprocessor, or other computing device. While aspects of embodiments of the present disclosure are illustrated or described as block diagrams, flowcharts, or using some other graphical representation, it will be understood that the blocks, devices, systems, techniques, or methods described herein may be used as non-limiting Examples are implemented in hardware, software, firmware, special purpose circuitry or logic, general purpose hardware or controllers, or other computing devices, or some combination thereof.
例如,根据本公开的实施例的方法或装置也可以借助于图8所示的计算设备3000的架构来实现。如图8所示,计算设备3000可以包括总线3010、一个或多个CPU 3020、只读存储器(ROM)3030、随机存取存储器(RAM)3040、连接到网络的通信端口3050、输入/输出组件3060、硬盘3070等。计算设备3000中的存储设备,例如ROM 3030或硬盘3070可以存储本公开提供的方法的处理和/或通信使用的各种数据或文件以及CPU所执行的程序指令。计算设备3000还可以包括用户界面3080。当然,图8所示的架构只是示例性的,在实现不同的设备时,根据实际需要,可以省略图8示出的计算设备中的一个或多个组件。For example, methods or apparatuses according to embodiments of the present disclosure may also be implemented with the aid of the architecture of the computing device 3000 shown in FIG. 8 . As shown in Figure 8, computing device 3000 may include a bus 3010, one or more CPUs 3020, read only memory (ROM) 3030, random access memory (RAM) 3040, communication port 3050 connected to a network, input/output components 3060, hard disk 3070, etc. The storage device in the computing device 3000, such as the ROM 3030 or the hard disk 3070, can store various data or files used for processing and/or communication of the methods provided by the present disclosure, as well as program instructions executed by the CPU. Computing device 3000 may also include user interface 3080. Of course, the architecture shown in FIG. 8 is only exemplary, and when implementing different devices, one or more components in the computing device shown in FIG. 8 may be omitted according to actual needs.
根据本公开的又一方面,还提供了一种计算机可读存储介质。图9示出了根据本公开的存储介质的示意图4000。According to yet another aspect of the present disclosure, a computer-readable storage medium is also provided. Figure 9 shows a schematic diagram 4000 of a storage medium in accordance with the present disclosure.
如图9所示,计算机存储介质4020上存储有计算机可读指令4010。当计算机可读指令4010由处理器运行时,可以执行参照以上附图描述的根据本公开的实施例的方法。本公开的实施例中的计算机可读存储介质可以是易失性存储器或非易失性存储器,或可包括易失性和非易失性存储器两者。非易失性存储器可以是只读存储器(ROM)、可编程只读存储器(PROM)、可擦除可编程只读存储器(EPROM)、电可擦除可编程只读存储器(EEPROM)或闪存。易失性存储器可以是随机存取存储器(RAM),其用作外部高速缓存。通过示例性但不是限制性说明,许多形式的RAM可用,例如静态随机存取存储器(SRAM)、动态随机存取存储器(DRAM)、同步动态随机存取存储器(SDRAM)、双倍数据速率同步动态随 机存取存储器(DDRSDRAM)、增强型同步动态随机存取存储器(ESDRAM)、同步连接动态随机存取存储器(SLDRAM)和直接内存总线随机存取存储器(DR RAM)。应注意,本文描述的方法的存储器旨在包括但不限于这些和任意其它适合类型的存储器。应注意,本文描述的方法的存储器旨在包括但不限于这些和任意其它适合类型的存储器。As shown in Figure 9, computer readable instructions 4010 are stored on computer storage medium 4020. When the computer readable instructions 4010 are executed by the processor, the methods according to the embodiments of the present disclosure described with reference to the above figures may be performed. Computer-readable storage media in embodiments of the present disclosure may be volatile memory or non-volatile memory, or may include both volatile and non-volatile memory. Non-volatile memory may be read-only memory (ROM), programmable read-only memory (PROM), erasable programmable read-only memory (EPROM), electrically erasable programmable read-only memory (EEPROM), or flash memory. Volatile memory may be random access memory (RAM), which acts as an external cache. By way of illustration, but not limitation, many forms of RAM are available, such as static random access memory (SRAM), dynamic random access memory (DRAM), synchronous dynamic random access memory (SDRAM), double data rate synchronous dynamic Follow machine access memory (DDRSDRAM), enhanced synchronous dynamic random access memory (ESDRAM), synchronous link dynamic random access memory (SLDRAM) and direct memory bus random access memory (DR RAM). It should be noted that memory for the methods described herein is intended to include, but is not limited to, these and any other suitable types of memory. It should be noted that memory for the methods described herein is intended to include, but is not limited to, these and any other suitable types of memory.
本公开的实施例还提供了一种计算机程序产品或计算机程序,该计算机程序产品或计算机程序包括计算机程序,该计算机程序存储在计算机可读存储介质中。计算机设备的处理器从计算机可读存储介质读取该计算机程序,处理器执行该计算机程序,使得该计算机设备执行根据本公开的实施例的方法。Embodiments of the present disclosure also provide a computer program product or computer program, which includes a computer program, and the computer program is stored in a computer-readable storage medium. The processor of the computer device reads the computer program from the computer-readable storage medium, and the processor executes the computer program, so that the computer device performs the method according to the embodiment of the present disclosure.
需要说明的是,附图中的流程图和框图,图示了按照本公开各种实施例的系统、方法和计算机程序产品的可能实现的体系架构、功能和操作。在这点上,流程图或框图中的每个方框可以代表一个模块、程序段、或代码的一部分,所述模块、程序段、或代码的一部分包含至少一个用于实现规定的逻辑功能的可执行指令。也应当注意,在有些作为替换的实现中,方框中所标注的功能也可以以不同于附图中所标注的顺序发生。例如,两个接连地表示的方框实际上可以基本并行地执行,它们有时也可以按相反的顺序执行,这依所涉及的功能而定。也要注意的是,框图和/或流程图中的每个方框、以及框图和/或流程图中的方框的组合,可以用执行规定的功能或操作的专用的基于硬件的系统来实现,或者可以用专用硬件与计算机指令的组合来实现。It should be noted that the flowcharts and block diagrams in the accompanying drawings illustrate the possible implementation architecture, functions and operations of systems, methods and computer program products according to various embodiments of the present disclosure. In this regard, each block in the flowchart or block diagrams may represent a module, segment, or portion of code that contains at least one element for implementing the specified logical function. Executable instructions. It should also be noted that, in some alternative implementations, the functions noted in the block may occur out of the order noted in the figures. For example, two blocks shown one after another may actually execute substantially in parallel, or they may sometimes execute in the reverse order, depending on the functionality involved. It will also be noted that each block of the block diagram and/or flowchart illustration, and combinations of blocks in the block diagram and/or flowchart illustration, can be implemented by special purpose hardware-based systems that perform the specified functions or operations. , or can be implemented using a combination of specialized hardware and computer instructions.
本公开使用了特定词语来描述本公开的实施例。如“第一/第二实施例”、“一实施例”、和/或“一些实施例”意指与本公开至少一个实施例相关的某一特征、结构或特点。因此,应强调并注意的是,本说明书中在不同位置两次或多次提及的“一实施例”或“一个实施例”或“一替代性实施例”并不一定是指同一实施例。此外,本公开的一个或多个实施例中的某些特征、结构或特点可以进行适当的组合。This disclosure uses specific words to describe embodiments of the disclosure. For example, "first/second embodiment", "an embodiment", and/or "some embodiments" means a certain feature, structure or characteristic related to at least one embodiment of the present disclosure. Therefore, it should be emphasized and noted that “one embodiment” or “an embodiment” or “an alternative embodiment” mentioned twice or more at different places in this specification does not necessarily refer to the same embodiment. . In addition, certain features, structures or characteristics of one or more embodiments of the present disclosure may be combined appropriately.
除非另有定义,这里使用的所有术语(包括技术和科学术语)具有与本申请所属领域的普通技术人员共同理解的相同含义。还应当理解,诸如在通常字典里定义的那些术语应当被解释为具有与它们在相关技术的上下文中的含义相一致的含义,而不应用理想化或极度形式化的意义来解释,除非这里明确地这样定义。Unless otherwise defined, all terms (including technical and scientific terms) used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. It should also be understood that terms such as those defined in ordinary dictionaries should be construed to have meanings consistent with their meanings in the context of the relevant technology and should not be interpreted in an idealized or highly formalized sense unless expressly stated herein Ground is defined this way.
上面是对本申请的说明,而不应被认为是对其的限制。尽管描述了本申请的若干示例性实施例,但本领域技术人员将容易地理解,在不背离本申请的新颖教学和优点的前提下可以对示例性实施例进行许多修改。因此,所有这些修改都意图包含在权利要求书所限定的本申请范围内。应当理解,上面是对本申请的说明,而不应被认为是限于所公开的特定实施例,并且对所公开的实施例以及其他实施例的修改意图包含在所附权利要求书的范围内。本申请由权利要求书及其等效物限定。 The above is a description of the present application and should not be considered as a limitation thereof. Although several exemplary embodiments of the present application have been described, those skilled in the art will readily appreciate that many modifications are possible in the exemplary embodiments without departing from the novel teachings and advantages of the present application. Accordingly, all such modifications are intended to be included within the scope of the application as defined by the claims. It is to be understood that the above is a description of the present application and should not be construed as limited to the particular embodiments disclosed, and that modifications to the disclosed embodiments as well as other embodiments are intended to be included within the scope of the appended claims. The application is defined by the claims and their equivalents.

Claims (18)

  1. 一种用于伪影去除的图像处理方法,包括:An image processing method for artifact removal, including:
    建立用于训练神经网络的训练数据集,其中,所述训练数据集包括多组图像样本,每组图像样本包括带伪影图像(Y)及与其对应的无伪影图像(X)和图像掩膜(I);Establish a training data set for training the neural network, wherein the training data set includes multiple groups of image samples, each group of image samples includes an image with artifacts (Y) and its corresponding image without artifacts (X) and ImageMask(I);
    对于所述多组图像样本中的任意一组图像样本,For any group of image samples among the plurality of groups of image samples,
    利用自适应卷积字典网络,对所述带伪影图像(Y)进行伪影去除处理,以得到处理后图像,Using an adaptive convolutional dictionary network, perform artifact removal processing on the image with artifacts (Y) to obtain the processed image,
    基于所述无伪影图像(X)和所述处理后图像、以及经所述图像掩膜(I)处理的目标函数对所述自适应卷积字典网络进行迭代训练,以优化所述自适应卷积字典网络的网络参数,The adaptive convolutional dictionary network is iteratively trained based on the artifact-free image (X) and the processed image, and the objective function processed by the image mask (I) to optimize the adaptive Network parameters of convolutional dictionary network,
    其中,所述自适应卷积字典网络包括基本伪影字典,所述基本伪影字典是不随样本变化的卷积字典并且包括伪影卷积核,并且通过所述基本伪影字典中的多个伪影卷积核与随样本变化的加权系数来确定用于所述图像样本的自适应卷积核,Wherein, the adaptive convolution dictionary network includes a basic artifact dictionary, which is a convolution dictionary that does not change with samples and includes an artifact convolution kernel, and through multiple artifacts in the basic artifact dictionary The artifact convolution kernel and the weighting coefficient that change with the sample are used to determine the adaptive convolution kernel for the image sample,
    其中,通过所述自适应卷积核与所述带伪影图像的图像特征的卷积来确定所述带伪影图像中的伪影图像,并从所述带伪影图像中去除所述伪影图像以得到所述处理后图像。Wherein, the artifact image in the artifact-bearing image is determined through convolution of the adaptive convolution kernel and the image features of the artifact-bearing image, and the artifact is removed from the artifact-bearing image. shadow image to obtain the processed image.
  2. 如权利要求1所述的图像处理方法,其中,所述第一数量的伪影卷积核指示伪影模式,所述图像特征指示所述伪影模式所在的位置,The image processing method of claim 1, wherein the first number of artifact convolution kernels indicates an artifact pattern, and the image feature indicates a location where the artifact pattern is located,
    其中,所述自适应卷积字典网络包括T级网络,其中,在第t级网络中,利用基于近端梯度下降的迭代更新规则对第t-1级网络输出的加权系数和图像特征进行更新,以得到第t级网络的加权系数和图像特征,其中t为大于1且小于等于T的整数。Wherein, the adaptive convolutional dictionary network includes a T-level network, wherein in the t-level network, the weighted coefficients and image features output by the t-1th level network are updated using an iterative update rule based on proximal gradient descent. , to obtain the weighting coefficients and image features of the t-th level network, where t is an integer greater than 1 and less than or equal to T.
  3. 如权利要求2所述的图像处理方法,其中,每级网络包括加权系数更新网络、图像特征更新网络、及伪影去除图像更新网络,其中,The image processing method of claim 2, wherein each level of network includes a weighted coefficient update network, an image feature update network, and an artifact removal image update network, wherein,
    加权系数更新网络、图像特征更新网络、及伪影去除图像更新网络包括残差网络结构及归一化处理层。The weighted coefficient update network, image feature update network, and artifact removal image update network include a residual network structure and a normalization processing layer.
  4. 如权利要求1所述的图像处理方法,其中,所述建立用于训练神经网络的训练数据集包括以下至少一项:The image processing method according to claim 1, wherein said establishing a training data set for training a neural network includes at least one of the following:
    对所述带伪影图像(Y)的像素值进行归一化处理;以及Normalize the pixel values of the artifact-bearing image (Y); and
    对所述带伪影图像(Y)进行随机裁剪以获得图像块,并按照预定的概率对所述图像块进行随机翻转处理。The image with artifacts (Y) is randomly cropped to obtain image blocks, and the image blocks are randomly flipped according to a predetermined probability.
  5. 如权利要求1所述的图像处理方法,其中,所述目标函数为基于所述无伪影图像(X)和所述处理后图像所构建的损失目标函数,The image processing method according to claim 1, wherein the objective function is a loss objective function constructed based on the artifact-free image (X) and the processed image,
    其中,所述基于所述无伪影图像(X)和所述处理后图像、以及目标函数对所述自适应卷积字典网络进行迭代训练,以优化所述自适应卷积字典网络的网络参数包括:Wherein, the adaptive convolutional dictionary network is iteratively trained based on the artifact-free image (X), the processed image, and an objective function to optimize network parameters of the adaptive convolutional dictionary network. include:
    计算损失目标函数并将其结果反向传播到所述自适应卷积字典网络,并基于自适应矩估计Adam算法优化所述自适应卷积字典网络的网络参数。The loss objective function is calculated and the result is back-propagated to the adaptive convolutional dictionary network, and the network parameters of the adaptive convolutional dictionary network are optimized based on the adaptive moment estimation Adam algorithm.
  6. 如权利要求1所述的图像处理方法,还包括:在训练完成后,对所述自适应卷积字典网络进行测试, The image processing method as claimed in claim 1, further comprising: after training is completed, testing the adaptive convolutional dictionary network,
    其中,所述对所述自适应卷积字典网络进行测试包括:Wherein, the testing of the adaptive convolutional dictionary network includes:
    对待测试的带伪影图像进行预处理,并输入到所述自适应卷积字典网络;Preprocess the image with artifacts to be tested and input it into the adaptive convolutional dictionary network;
    利用自适应卷积字典网络,对所述待测试的带伪影图像进行处理,以得到去除伪影的处理后图像。The image with artifacts to be tested is processed using an adaptive convolutional dictionary network to obtain a processed image with artifacts removed.
  7. 如权利要求1所述的图像处理方法,其中,所述伪影图像为金属伪影,所述带伪影图像为带金属伪影的计算机断层扫描CT图像,The image processing method according to claim 1, wherein the artifact image is a metal artifact, and the artifact image is a computed tomography CT image with metal artifact,
    所述训练数据集包括多组CT图像样本,每组图像样本包括带金属伪影的CT图像及与其对应的无金属伪影的CT图像和非金属区掩膜;The training data set includes multiple groups of CT image samples, each group of image samples includes a CT image with metal artifacts and a corresponding CT image without metal artifacts and a non-metal area mask;
    所述自适应卷积字典网络包括基本金属伪影字典,所述基本金属伪影字典是不随CT图像样本变化的金属伪影卷积字典并且包括金属伪影卷积核,并且通过所述基本金属伪影字典中的多个金属伪影卷积核与随CT图像样本变化的加权系数来确定用于所述CT图像样本的自适应卷积核,其中,所述金属伪影卷积核指示金属伪影模式,所述图像特征指示所述金属伪影模式所在的位置。The adaptive convolution dictionary network includes a basic metal artifact dictionary, which is a metal artifact convolution dictionary that does not change with CT image samples and includes a metal artifact convolution kernel, and through the basic metal artifact dictionary Multiple metal artifact convolution kernels in the artifact dictionary and weighting coefficients that change with the CT image sample are used to determine an adaptive convolution kernel for the CT image sample, wherein the metal artifact convolution kernel indicates metal Artifact pattern, the image feature indicates where the metal artifact pattern is located.
  8. 如权利要求7所述的图像处理方法,其中,每级网络包括加权系数更新网络、金属伪影图像特征更新网络、及金属伪影去除图像更新网络,其中,The image processing method according to claim 7, wherein each level of the network includes a weighted coefficient update network, a metal artifact image feature update network, and a metal artifact removal image update network, wherein,
    加权系数更新网络、金属伪影图像特征更新网络、及金属伪影去除图像更新网络包括残差网络结构;并且The weighted coefficient update network, the metal artifact image feature update network, and the metal artifact removal image update network include a residual network structure; and
    加权系数更新网络包括:线性层、修正线性单元ReLU层、跨链接层,及批标准化BN层;The weighted coefficient update network includes: linear layer, modified linear unit ReLU layer, cross-link layer, and batch normalized BN layer;
    金属伪影图像特征更新网络包括:卷积层、BN层、ReLU层,及跨链接层;The metal artifact image feature update network includes: convolution layer, BN layer, ReLU layer, and cross-link layer;
    金属伪影去除图像更新网络包括:卷积层、BN层、ReLU层,及跨链接层。The metal artifact removal image update network includes: convolution layer, BN layer, ReLU layer, and cross-link layer.
  9. 一种用于伪影去除的图像处理方法,包括:An image processing method for artifact removal, including:
    获取待处理的输入图像;Get the input image to be processed;
    利用自适应卷积字典网络,对所述输入图像进行处理,以得到去除伪影的处理后图像,Using an adaptive convolutional dictionary network, the input image is processed to obtain a processed image with artifacts removed,
    其中,所述自适应卷积字典网络是基于伪影数据库(D)训练的,并且包括T级网络,其中,第1级网络基于所述输入图像输出第1级图像特征和第1级伪影去除图像;第t级网络至少部分基于第t-1级网络输出的第t-1级图像特征和第t-1级伪影去除图像,输出第t级图像特征和第t级伪影去除图像,其中t大于1且小于等于T;第T级网络基于第T-1级网络输出的第T-1级图像特征和第T-1级伪影去除图像,输出第T级伪影去除图像作为所述去除伪影的处理后图像。Wherein, the adaptive convolutional dictionary network is trained based on the artifact database (D) and includes a T-level network, wherein the level 1 network outputs level 1 image features and level 1 artifacts based on the input image. Remove the image; the t-th level network outputs the t-level image features and the t-th level artifact removal image based at least in part on the t-1 level image features and the t-1 level artifact removal image output by the t-1 level network. , where t is greater than 1 and less than or equal to T; the T-level network is based on the T-1-th level image features and the T-1-th level artifact removal image output by the T-1-th level network, and outputs the T-th level artifact removal image as The processed image after artifact removal.
  10. 如权利要求9所述的图像处理方法,其中,所述自适应卷积字典网络包括基本伪影字典,所述基本伪影字典是不随输入图像变化的卷积字典并且包括伪影卷积核,The image processing method according to claim 9, wherein the adaptive convolution dictionary network includes a basic artifact dictionary, the basic artifact dictionary is a convolution dictionary that does not change with the input image and includes an artifact convolution kernel,
    确定第t级网络的第t级加权系数,通过所述基本伪影字典中的多个伪影卷积核与所述第t级加权系数来确定用于所述第t级网络的自适应卷积核;并且基于所述自适应卷积核与所述第t级网络的图像特征确定第t级伪影去除图像。Determine the t-th level weighting coefficient of the t-th level network, and determine the adaptive convolution for the t-th level network through multiple artifact convolution kernels in the basic artifact dictionary and the t-th level weighting coefficient. convolution kernel; and determine the t-th level artifact removal image based on the image features of the adaptive convolution kernel and the t-th level network.
  11. 如权利要求9所述的图像处理方法,其中,每级网络包括加权系数更新网络、图像特征更新网络、及伪影去除图像更新网络,其中, The image processing method according to claim 9, wherein each level of the network includes a weighted coefficient update network, an image feature update network, and an artifact removal image update network, wherein,
    加权系数更新网络、图像特征更新网络、及伪影去除图像更新网络包括残差网络结构及归一化处理层。The weighted coefficient update network, image feature update network, and artifact removal image update network include a residual network structure and a normalization processing layer.
  12. 如权利要求9所述的图像处理方法,其中,所述待处理的输入图像是应用了图像掩膜(I)后的图像。The image processing method according to claim 9, wherein the input image to be processed is an image after applying the image mask (I).
  13. 如权利要求12所述的图像处理方法,其中,所述伪影为金属伪影,所述待处理的输入图像为带金属伪影的计算机断层扫描CT图像,所述图像掩膜(I)为与带金属伪影的CT图像对应的非金属区掩膜,The image processing method according to claim 12, wherein the artifact is a metal artifact, the input image to be processed is a computed tomography CT image with metal artifact, and the image mask (I) is Non-metal area mask corresponding to CT image with metal artifacts,
    其中,每级网络包括加权系数更新网络、金属伪影图像特征更新网络、及金属伪影去除图像更新网络,其中,Among them, each level of network includes a weighted coefficient update network, a metal artifact image feature update network, and a metal artifact removal image update network, where,
    加权系数更新网络、金属伪影图像特征更新网络、及金属伪影去除图像更新网络包括残差网络结构;并且The weighted coefficient update network, the metal artifact image feature update network, and the metal artifact removal image update network include a residual network structure; and
    加权系数更新网络包括:线性层、修正线性单元ReLU层、跨链接层,及批标准化BN层;The weighted coefficient update network includes: linear layer, modified linear unit ReLU layer, cross-link layer, and batch normalized BN layer;
    金属伪影图像特征更新网络包括:卷积层、BN层、ReLU层,及跨链接层;The metal artifact image feature update network includes: convolution layer, BN layer, ReLU layer, and cross-link layer;
    金属伪影去除图像更新网络包括:卷积层、BN层、ReLU层,及跨链接层。The metal artifact removal image update network includes: convolution layer, BN layer, ReLU layer, and cross-link layer.
  14. 一种用于伪影去除的图像处理装置,包括:An image processing device for artifact removal, including:
    训练数据集建立模块,被配置为:建立用于训练神经网络的训练数据集,其中,所述训练数据集包括多组图像样本,每组图像样本包括带伪影图像(Y)及与其对应的无伪影图像(X)和图像掩膜(I);A training data set creation module configured to: create a training data set for training a neural network, wherein the training data set includes multiple groups of image samples, and each group of image samples includes an artifact image (Y) and its Corresponding artifact-free image (X) and image mask (I);
    自适应卷积字典网络,被配置为:对于所述多组图像样本中的任意一组图像样本,对所述带伪影图像(Y)进行伪影去除处理,以得到处理后图像;An adaptive convolutional dictionary network configured to: perform artifact removal processing on the artifact-bearing image (Y) for any group of image samples among the plurality of groups of image samples to obtain a processed image;
    训练模块,被配置为:基于所述无伪影图像(X)和所述处理后图像、以及经所述图像掩膜(I)处理的目标函数对所述自适应卷积字典网络进行迭代训练,以优化所述自适应卷积字典网络的网络参数;a training module configured to iteratively train the adaptive convolutional dictionary network based on the artifact-free image (X), the processed image, and an objective function processed by the image mask (I) , to optimize the network parameters of the adaptive convolutional dictionary network;
    其中,所述自适应卷积字典网络包括基本伪影字典,所述基本伪影字典是不随样本变化的卷积字典并且包括伪影卷积核,并且通过所述基本伪影字典中的多个伪影卷积核与随样本变化的加权系数来确定用于所述图像样本的自适应卷积核,Wherein, the adaptive convolution dictionary network includes a basic artifact dictionary, which is a convolution dictionary that does not change with samples and includes an artifact convolution kernel, and through multiple artifacts in the basic artifact dictionary The artifact convolution kernel and the weighting coefficient that change with the sample are used to determine the adaptive convolution kernel for the image sample,
    其中,通过所述自适应卷积核与所述带伪影图像的图像特征的卷积来确定所述带伪影图像中的伪影图像,并从所述带伪影图像中去除所述伪影图像以得到所述处理后图像。Wherein, the artifact image in the artifact-bearing image is determined through convolution of the adaptive convolution kernel and the image features of the artifact-bearing image, and the artifact is removed from the artifact-bearing image. shadow image to obtain the processed image.
  15. 一种用于伪影去除的图像处理装置,包括:An image processing device for artifact removal, including:
    图像获取模块,被配置为:获取待处理的输入图像;The image acquisition module is configured to: acquire the input image to be processed;
    图像处理模块,被配置为:利用自适应卷积字典网络,对所述输入图像进行处理,以得到去除伪影的处理后图像;An image processing module configured to: use an adaptive convolutional dictionary network to process the input image to obtain a processed image with artifacts removed;
    其中,所述自适应卷积字典网络是基于伪影数据库(D)训练的,并且包括T级网络,其中,第1级网络基于所述输入图像输出第1级图像特征和第1级伪影去除图像;第t级网络至少部分基于第t-1级网络输出的第t-1级图像特征和第t-1级伪影去除图像,输出第t级图像特征和第t级伪影去除图像,其中t大于1且小于等于T;第T级网络基于第T-1级网络输出的第T-1 级图像特征和第T-1级伪影去除图像,输出第T级伪影去除图像作为所述去除伪影的处理后图像。Wherein, the adaptive convolutional dictionary network is trained based on the artifact database (D) and includes a T-level network, wherein the level 1 network outputs level 1 image features and level 1 artifacts based on the input image. Remove the image; the t-th level network outputs the t-level image features and the t-th level artifact removal image based at least in part on the t-1 level image features and the t-1 level artifact removal image output by the t-1 level network. , where t is greater than 1 and less than or equal to T; the T-th level network is based on the T-1-th level network output level image features and the T-1th level artifact removal image, and output the T-th level artifact removal image as the processed image after artifact removal.
  16. 一种计算机程序产品,所述计算机程序产品包括计算机程序,所述计算机程序在被处理器运行时用于实现如权利要求1-13中任一项所述的方法。A computer program product, which includes a computer program that, when run by a processor, is used to implement the method according to any one of claims 1-13.
  17. 一种计算机可读存储介质,其上存储有计算机程序,所述计算机程序在被处理器执行时用于实现如权利要求1-13中任一项所述的方法。A computer-readable storage medium having a computer program stored thereon, the computer program being used to implement the method according to any one of claims 1-13 when executed by a processor.
  18. 一种计算机设备,所述计算机设备包括:A kind of computer equipment, described computer equipment includes:
    处理器、通信接口、存储器和通信总线;Processors, communication interfaces, memory and communication buses;
    其中,所述处理器、所述通信接口和所述存储器通过所述通信总线完成相互间的通信;所述通信接口为通信模块的接口;Wherein, the processor, the communication interface and the memory complete communication with each other through the communication bus; the communication interface is an interface of a communication module;
    所述存储器,用于存储计算机程序,并将所述计算机程序传输给所述处理器;The memory is used to store a computer program and transmit the computer program to the processor;
    所述处理器,用于调用存储器中计算机程序执行权利要求1-13中任一项所述的方法。 The processor is configured to call a computer program in a memory to execute the method described in any one of claims 1-13.
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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108122265A (en) * 2017-11-13 2018-06-05 深圳先进技术研究院 A kind of CT reconstruction images optimization method and system
US20190147588A1 (en) * 2017-11-13 2019-05-16 Siemens Healthcare Gmbh Artifact identification and/or correction for medical imaging
CN111127354A (en) * 2019-12-17 2020-05-08 武汉大学 Single-image rain removing method based on multi-scale dictionary learning
CN112258423A (en) * 2020-11-16 2021-01-22 腾讯科技(深圳)有限公司 Deartifact method, device, equipment and storage medium based on deep learning
CN114283088A (en) * 2021-12-24 2022-04-05 中北大学 Low-dose CT image noise reduction method and device
CN115131452A (en) * 2022-04-19 2022-09-30 腾讯医疗健康(深圳)有限公司 Image processing method and device for artifact removal

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108122265A (en) * 2017-11-13 2018-06-05 深圳先进技术研究院 A kind of CT reconstruction images optimization method and system
US20190147588A1 (en) * 2017-11-13 2019-05-16 Siemens Healthcare Gmbh Artifact identification and/or correction for medical imaging
CN111127354A (en) * 2019-12-17 2020-05-08 武汉大学 Single-image rain removing method based on multi-scale dictionary learning
CN112258423A (en) * 2020-11-16 2021-01-22 腾讯科技(深圳)有限公司 Deartifact method, device, equipment and storage medium based on deep learning
CN114283088A (en) * 2021-12-24 2022-04-05 中北大学 Low-dose CT image noise reduction method and device
CN115131452A (en) * 2022-04-19 2022-09-30 腾讯医疗健康(深圳)有限公司 Image processing method and device for artifact removal

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