WO2023161697A1

WO2023161697A1 - Smart portable container that adjusts the storage conditions of medicine for specific patients

Info

Publication number: WO2023161697A1
Application number: PCT/IB2022/061482
Authority: WO
Inventors: Faezeh GHORBANI; Arsalan ANVARI
Original assignee: Ghorbani Faezeh
Priority date: 2022-11-28
Filing date: 2022-11-28
Publication date: 2023-08-31

Abstract

The mechatronic container device for storing special drugs sensitive to impact and temperature with the ability to maintain the quality of the drug at different temperatures, the warning of unusual physical impact, the ability to remind the time of use, and the ability to connect to a smart mobile phone equipped with an antiseptic for the claimed injection equipment

Description

Smart portable container that adjusts the storage conditions of medicine for specific patients

A61J1/03

Smart medicine box and controlling method thereof

TWI701029B

This disclosure is related to a smart medicine box and the controlling method thereof. The smart medicine box comprises an upper body and a lower body, further, the upper body comprises a biometric identifier, a screen, a main controller, a plurality of lids, and a plurality of latching devices, and the lower body comprises a plurality of cells. Each cell corresponds to a lid so that the cell with the lid forms a lay-up space for placing the medicine. Wherein the plurality of latching devices is coupled to the main controller, each of the latching devices can lock some of the plurality of lids, and then one of the lids is controlled by the control signal of the main controller to determine the lid can be turned on or not. In this disclosure, the lid can be turned on only when the user takes the medicine at the correct time. All the lids will be locked when the user takes the medicine at an incorrect time or tries to reuse the medicine. Therefore, this disclosure is extremely suitable for the elder, disabled or poor memory people, and can effectively provide the user to take the medicine at the correct time.

In this invention, the inventor enables the person to access the appropriate medication at the right time by connecting the device to the smartphone and by recognizing the consumer person.

MEDICINE CONTAINER AND MEDICATION AUXILIARY DEVICE

United States Patent Application 20140042052

A medicine container detachably disposed in an electronic medicine box includes an accommodating portion and a cover portion. The accommodating portion has a medicine containing space. The cover portion is movably connected to the accommodating portion and has a barcode. When the medicine container is disposed in the electronic medicine box, the barcode is readable. A medication auxiliary device including a plurality of the above medicine containers and an electronic medicine box is also disclosed.

In this invention, the inventor has managed consumption by placing different medications in small packages together that each contains a door inside a larger device

INTELLIGENT EXTENSION MEDICINE BOX SYSTEM

United States Patent Application 20160331643

An intelligent extension medicine box system, including a main control box and more than one sub-medicine box, is provided. The main controller is arranged in the main control box, wherein a main connector is arranged on one side of the main control box. The sub-medicine box is formed by a box body and a box cover, wherein the inner part of the box body is divided into a medicine storage chamber and a sub-control chamber from top to bottom. A medicine bin with an inverted semi-conical bottom is arranged in the medicine storage chamber, wherein a medicine box light-emitting device and a detection device are arranged at the bottom of the medicine bin. A left connector and a right connector are arranged at the two sides of the sub-control chamber, wherein the left connector can be connected to the main control box or the right connectors of other sub-medicine boxes through the main connector.

In this invention; the inventor has managed medicine consumption with the possibility of connecting multiple boxes together in series and connecting them to a central processor by using light and sound.

Heated drug box

United States Patent 5183994

A heated drug box for transporting emergency drugs and I. V. solutions at a safe working temperature wherein the medical supplies usually required first are accessible in a side compartment through the door means in the side of the box. Other door means are provided at the top of the box through which the main compartment is accessible. The side and main compartments are in thermal contact with a heater means located between the side and main compartments for heating the contents of the box to a safe working temperature.

In this invention, the inventor guarantees the temperature of some drugs sensitive to low temperatures by using a portable bag for safe transmission.

MEDICATION DISPENSING SYSTEM

United States Patent Application 20190254931

Methods and systems for a drug supply with an associated dosage regimen are described. A plurality of dosage containers is sequentially stored in drug boxes. The dosage containers are associated with the first time of treatment. The drug boxes are associated with a certain recurring time, e.g., morning, afternoon, and evening or four boxes are associated with four times a day. The entire day is covered by a plurality of drug boxes for treatment. This organizes the drugs such that compliance with complex treatment regimens may be increased. The drugs in each of the dosage containers need not be the same dosage or even the same drugs each time.

In this invention, the inventor has managed medicine consumption in sequential doses by using a vertical stand and putting the drug packages based on the dose of consumption classified on each other with the possibility of pulling out from the lowest row.

The mechatronic storage container for special drugs sensitive to heat and impact is an invention in the field of storage and transportation equipment for special drugs, especially with the ability to warn consumption time and maintain proper storage temperature conditions. Considering the increasing need of people for time reminder equipment and the proper storage of medicine and the need of many of these people for different trips and the lack of suitable storage and transportation containers, in this invention, an attempt has been made to solve the above problems by using existing technologies and with this container, people who are mentally retarded or blind or who need to inject at specific times can use this device at home or on a trip with appropriate settings without fear of forgetting and the conditions of keeping drugs, syringes and vials. Also, the ability to connect the mechatronic storage container to a smart mobile phone has provided the possibility of receiving warnings and reminders at the right time.

The advancement of technology improves people's life and diet but makes modern human beings be much troubled by the diseases of civilization, such as chronic diseases including hypertension, cancer, cardiovascular disease, diabetes, or the like; or mental illnesses including depressive illness, bipolar disorder, or the like. The treatments for these diseases need to rely on long-term medical treatment. Although technology is getting more and more advanced than the prior art and the digitized era has come, the conditions of prescription drug misuse still come out one after the other.

In the current hospital administration condition, after the patient goes to the hospital or clinic for the consultation, the patient receives several days of medicines, which are usually placed in a medicine bag, and the hospital or clinic staff records the medication information, such as the time interval and the number of the medications, on the medicine bag. The patient has to take the medicines from the medicine bag according to the doctor's advice. Of course, busy office workers or elderly persons tend to forget to take the medicine or forget which medicines should be taken. In view of this, some manufacturers have produced medicine boxes to assist in solving the above-mentioned problem and make the patient dispense the medicines according to the dosage for each day and each time when the patient still remembers the information. Then, the patient only has to take the medicines in order. However, the above-mentioned method still needs the patient to remember the information. In the condition where the medicine types are diversified and the dosages may vary in every medication, this procedure provides an extremely high risk of medication error for elderly persons or critically ill patients. The typical medicine box only provides the function for the user to place the medicines. Even if some medicine boxes allow the user to mark an easy record on the container to record the common period to take medicines, such as before or after breakfast, lunch, and dinner, there are considerable risks to cause prescription drug misuse. For example, since the medicines are dispensed by the non-expert, either the family member, the caregiver, or the patient himself or herself, at home, the patient may take the wrong medicines. More particularly, upon medication, the patient cannot obtain the reference information to know whether the medication is correct or not. Thus, it is further difficult to decrease the risk of medication error. Generally speaking, the most frequently seen medication error at present includes taking the incorrect medicine, taking the medicine at the incorrect time, forgetting to take which kind of medicine, or the like, and the current industry does not provide a better solution.

Therefore, it is important subject to provide a medicine container, which can decrease the opportunity of dispensing medicines by non-experts, can assist in solving the medicine-taking problem, can precisely record the medication reference information, can remind the patient to take the medicine or remind the doctor's advice of the patient at the suitable time, and can solve the problem of the high medication error at present.

We all know the importance of taking medicines on time. The busyness and complications of life may sometimes cause us to face problems such as forgetting the time to take the medicine, doubting whether we have taken the medicine or not Delay in taking medication, and so on. The good news is that this device can somewhat reduce many of the stresses related to take the medicine and it also provides a suitable storage place with higher security for all kinds of medicines.

Moving, monitoring the amount and the sequence of taking medicines for certain patients, or even knowing the type and amount of medications stored by people in personal places, knowing about the expiration time of some drugs and the possibility of monitoring young or elderly patients who do not have the ability or attention to deal with their illness is one of the shortcomings of the medical industry. Therefore, in this invention, an attempt has been made to remove these problems by providing a smart drug container with the ability to adjust the appropriate temperature for medicines sensitive to temperature with lights that indicate when to use each drug, with a part equipped with UV lamps to disinfect drugs that need to be injected, with a cooling system and a backup battery for emergency cases or carrying medicines, and the possibility of connecting to smart phones and gadgets to inform people about the conditions of taking medicine.

Solution of problem

We used a container with several functions to solve the problem of storing, remembering, transporting, and disinfecting syringes and vials. The portable electronic container (1) supported by a handle (2) for easier carrying is equipped with a screen protector (3) and a keyboard protector (4) against physical damage and water corrosion. Also, the air conditioning port (5) can be seen on the same level as the environment. When the door of the device (6) is opened, the location of the drugs (7) is available. We also use valve (8) to ventilate the air inside. This valve (8) is made up of two air inlet and outlet sections so that maximum ventilation and a decrease or increase in temperature can take place in it. The basket (9) will be placed in the low part of the container, which is designed for easier washing and disinfection with the ability to separate. In this basket, we have several separate places for placing medicine (10), and in the part where medicine and equipment need to be disinfected, a reflector of the ultraviolet emitter (12) is used. Due to the possibility of separation and exposure to water, the ultraviolet emitters (12) are placed inside the body (7) and are irradiated into the basket space by a prism or mirror.

For easier carrying of the basket, a sliding handle (11) is installed in it. The basket is cribriform on the side walls to create proper ventilation. In the upper part of the basket, we see the quick access container, which is partitioned for different days of the week. We have 8 outputs in the radiation port (13), which includes the ultraviolet emitter in addition to the days of the week (15). The transmission of light to the outside can be done by a mirror or an optical fiber. The caps (16) also protect the drugs inside the container (17) to prevent unwanted movement during transportation. In the electronic circuits of this device, two processors are considered, one of which is the main one and the other one is the side one for the audio circuit. The main processor of the device (18) is AVR and has 7 ports with different efficiencies. Port A is intended for connecting to sensors and measuring battery voltage, which will be connected to the related module and connector (47) through connector (21). Port B will be the output of simple and ultraviolet LED indicators, which are connected to the connector (59) through the connector (20). We have port C and the connector (19) to receive touch keyboard commands selected from capacitive touch type, which made it possible to exchange keyboard data from the connector (60). Port D only receives and sends data from the Bluetooth port (22) and activates the audio warning if this module (22) is separated or too far from the smartphone.

The port controls the required outputs of the fans and the cooling/heating element. We need an operational amplifier (29) to the output connector (26) due to the weak outputs of the processor. The connector (26) is connected with the connector (39) and in addition to sending power information, there is also in all connectors. Port F sends commands directly to the display (30). This display (30) is installed behind the protector (3). The power of the above circuit is supplied from the connector (23) for entering and exiting and connecting to the battery. At the arrival of the diode bridge (24) along with the capacitor (25), they perform rectification from alternating or direct voltage, even in the case of reverse connection, to avoid damage. Then by entering the 5-volt regulator (27) and capacitor (28), the processors will be powered. The fan or fans (31) in this device should reduce or increase their speed based on the change in the required temperature so that the temperature exchange takes place properly and optimally. For this purpose, we use brushless motors (31) which change with speed frequency change. The electrical power source of this device is a rechargeable battery that is installed on the bottom of the medicine storage container and can be charged through a USB cable. The input signals from the amplifier (29) need another stage of amplification so that they are not damaged by the operation of the motor bobbins.

Three positive bipolar transistors (32) that are stimulated by the output of resistors (36) are used in the base, and we use the negative feedback of resistors (37) to prevent saturation and noise. Considering the required high power and relatively high amperage, we used a relay (34) to power the cooling element - TEG - (33). In this module, the connector (38) is used to control the recording and playback of audio messages, and the LED indicator (35) will show warnings with a blinking pattern. As mentioned earlier, we have used the connector (47) to connect the sensors, that we have the internal temperature sensor (42), the external temperature sensor (40), the harmful gas sensor (41), the GPS sensor, and the shock sensor (44), which are stimulated by changing the magnetic flux (43). By installing a Bluetooth connector in this device, it is possible to connect and manage the device through smartphones. We place the resistor to prevent diode signal return (46) and to match the impedance (45). By installing the appropriate application on the mobile phone, we experience a permanent warning in case of a high strike or change in the harmful temperature of the drug. It should be noted that the settings of the two mobile phone inputs are visible through the Bluetooth port and the keyboard, and the display of information is visible through the phone screen and the screen.

The voice record and playback circuit are suitable for people with disabilities and the connector (51) is used for powering and sending/receiving information. The keys (48) and (49) are designed to record and playback the message during the test, and the processor (50) and the gate (52) are designed to control the sound memory integrated circuit (53). The messages recorded from the microphone (55) are played by the speaker (54). It was mentioned earlier to control the LEDs of the days of the week display, we put LEDs (57) which are matched by suitable resistors with the input voltage. To turn on UV LEDs (12) according to the sensitivity of the disinfectant circuit, we have the positive type transistor (58) for powering and the photocell controller (56) so that the radiation action is carefully performed and controlled. The Capacitive touch keyboard circuit, which is based on the change of capacitance that occurs when the dielectric of the hand approaches, is on a screen with 15 keys (63), the light of which is provided by LEDs (62) and resistance (61). Output commands from connector (65) are transferred to connector (60) and power and data are exchanged from connector (64).

Advantage effects of invention

This device can be used as a general extension in domestic refrigerators as an option

It can be used exclusively for the consumption of some special patients

This device can be helpful for infirm or elderly patients who have the possibility of taking the wrong medicine or forgetting to take the medicine.

Storing special drugs sensitive to impact and temperature

The ability to maintain the quality of the drug at different temperatures

The warning of unusual physical impact

The ability to remind the time of use

The ability to connect to a smart mobile phone

: In the upper part, the three-dimensional view is shown in the closed state, and in the lower part, it shows the device door in the open state.

: It shows the medicines basket in the safe container

: In the upper part, it shows the details of the quick-access container when the doors are closed and in the lower part when the doors are open

: It shows the dimensions and sizes of the cooling container and main protective

: It shows the dimensions and sizes of the container of the main basket of medicines

: It shows the dimensions and sizes of the quick-access basket

: The proposed electronic circuit of the main processor is shown

: It shows the matching circuit of a brushless motor and cooling element

: It shows the sensors module

: It shows the audio module for recording and playback voice

: It shows LED and UV indicators

: It shows the circuit of the touch keyboard

: 1. The portable electronic container 2.handle 3. A screen protector 4. A keyboard protector 5. The air conditioning port 6. The door 7. The location of the drugs 8. The valve 13. The radiation port

: 9. The basket 10. Placing medicine 11. A sliding handle 12. The ultraviolet emitter

: 15. The week 16. The caps 17. The container

: It shows the dimensions and sizes of the quick-access basket

: 18. The main processor 19. The connector 20. Connector 21. Connector 22. The Bluetooth port 23. The connector 24. The diode bridge 25. The capacitor 27. The 5-volt regulator 28. Capacitor 29. The amplifier 30. This display

: 31. brushless motors 32. Three positive bipolar transistors 33. The cooling element - TEG 34. A relay 35. The LED indicator 36. The output of resistors 37. The negative feedback of resistors 38. The connector 39. The connector

: 40. the external temperature sensor 41. The harmful gas sensor 42. The internal temperature sensor 43. The magnetic flux 44. The shock sensor 45. The impedance 46. The resistor 47. The connector

: 48, 49. The keys 50. The processor 51. The connector 52. The gate 53. The sound memory integrated circuit 55. The microphone 54. The speaker

: 56. the photocell controller 57. LEDs 58. The positive type transistor 59. The connector

: 60. Connector 61. Resistance 62. LEDs 63. Keys 64. Connector 65. Connector

Examples

According to the capabilities of this device, after charging and connecting to a mobile phone, it can be used for diabetics, immunosuppressive diseases, patients with blood clot problems, CKD, etc. These patients should always carry their special medicines, which are generally sensitive to temperature changes. In addition, this device can be helpful for infirm or elderly patients who have the possibility of taking the wrong medicine or forgetting to take the medicine.

This device can be used as a general extension in domestic refrigerators as an option, or it can be used exclusively for the consumption of some special patients.

Claims

The mechatronic container device for storing special drugs sensitive to impact and temperature with the ability to maintain the quality of the drug at different temperatures, the warning of unusual physical impact, the ability to remind the time of use, and the ability to connect to a smart mobile phone equipped with an antiseptic for the claimed injection equipment is that includes the following main parts:
The main carrying or storage container that includes mechanical and electronic pieces, medicines, display, and keyboard.

Cribriform basket for placing secondary drugs with the ability of air conditioning, ultraviolet transfer, and separation from the main container.

The quick access drug box that is placed on the cribriform basket can be seen when the main door is opened which, in addition to categorizing drugs, can show the required drug.

Temperature control system by cooling element equipped with brushless fan

Equipment for irradiation and control of disinfectant ultraviolet radiation

Registration and impact warning module

Audio messages record and playback system

Electronic processor with the ability to receive, record, and send information and commands to mobile phones and existing modules in the device
The method of indirect transmission of radiation in disinfection equipment and drug container display is claimed.
According to main claim No. 2, the transmission of ultraviolet radiation (UVC) to the receiving place is done by the phenomenon of light refraction and light transmission to maintain the ability to wash the portable basket.
According to main claim No. 1, the container for carrying or storing medicine with the ability to transfer data to a mobile phone has used a wireless connection under Bluetooth.
According to claim No. 4, measuring the amount and radiation of the ultraviolet spectrum will be controlled by a sensor sensitive to this radiation and transfer data to the processor.
According to main claim No. 1, based on the existing description and figures, disinfection of medicine and equipment is done by ultraviolet with the ability to measure the intensity and duration of radiation.
According to main claim No.1, energy consumption optimization in controlling the temperature inside the container is done by the processor and the brushless fan motor control at different temperatures.
According to claim No. 7, receiving temperature information at two points outside and inside the container has provided processing the performance rate of temperature control equipment.
According to the main claim No. 1, based on the description of temperature control in reducing or increasing and preventing freezing and high-temperature degradation is performed by the semiconductor cooling element (TEG).
According to main claim No. 1, an impact sensor with the ability to record the impact and shock intensity and intensity warning have been used to maintain the safety of drugs sensitive to impact with specific containers.
According to main claim No. 1, placing the touch key module under the body surface and maintaining integrity for high resistance to washing is performed based on the existing technical figure.
According to the main claim No. 1, using audio warning with the ability to record and playback the desired message along with braille lines bumps in the container, the possibility of use is provided for the blind