WO2023141305A3 - Assays, test kits and methods for detection of lacritin - Google Patents

Assays, test kits and methods for detection of lacritin Download PDF

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Publication number
WO2023141305A3
WO2023141305A3 PCT/US2023/011291 US2023011291W WO2023141305A3 WO 2023141305 A3 WO2023141305 A3 WO 2023141305A3 US 2023011291 W US2023011291 W US 2023011291W WO 2023141305 A3 WO2023141305 A3 WO 2023141305A3
Authority
WO
WIPO (PCT)
Prior art keywords
lacritin
test
molecule
assays
test kits
Prior art date
Application number
PCT/US2023/011291
Other languages
French (fr)
Other versions
WO2023141305A2 (en
Inventor
Sergei Svarovsky
Alim SEIT-NEBI
Original Assignee
Sapphire Biotech, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sapphire Biotech, Inc. filed Critical Sapphire Biotech, Inc.
Publication of WO2023141305A2 publication Critical patent/WO2023141305A2/en
Publication of WO2023141305A3 publication Critical patent/WO2023141305A3/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G01N33/54387—Immunochromatographic test strips
    • G01N33/54388—Immunochromatographic test strips based on lateral flow

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Assays, test kits and methods for detecting and measuring monomeric lacritin in a test sample are provided herein. A method includes the steps of obtaining the test specimen from a subject, transferring the test specimen to a sample receiving portion of an assay of a test kit, and reading the results from the assay. An exemplary test kit can comprise a first molecule having a first affinity to bind to a first portion of monomeric lacritin. In some contemplated test kits, a second molecule having a second affinity to bind to a second portion of monomeric lacritin is provided. In some contemplated test kits, a second molecule is provided, wherein the first molecule has a second affinity to bind to a portion of the second molecule.
PCT/US2023/011291 2022-01-20 2023-01-20 Assays, test kits and methods for detection of lacritin WO2023141305A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202263301437P 2022-01-20 2022-01-20
US63/301,437 2022-01-20

Publications (2)

Publication Number Publication Date
WO2023141305A2 WO2023141305A2 (en) 2023-07-27
WO2023141305A3 true WO2023141305A3 (en) 2023-10-19

Family

ID=87349238

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2023/011291 WO2023141305A2 (en) 2022-01-20 2023-01-20 Assays, test kits and methods for detection of lacritin

Country Status (1)

Country Link
WO (1) WO2023141305A2 (en)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7491551B2 (en) * 1997-03-06 2009-02-17 Quidel Corporation Quantitative lateral flow assays and devices
US20120270238A1 (en) * 2009-10-22 2012-10-25 Moro Ricardo J Peptides That Bind the Alpha-Fetoprotein (AFP) Receptor and Uses Thereof
US20170176457A1 (en) * 2014-03-12 2017-06-22 University Of Virginia Patent Foundation Compositions and methods for treating eye infections and disease
US20180214545A1 (en) * 2017-02-01 2018-08-02 James Madison University Novel methods and reagents for diagnosing sjögren's syndrome
US20200261905A1 (en) * 2016-11-23 2020-08-20 Bio-Rad Laboratories, Inc. Lateral flow assay device

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7491551B2 (en) * 1997-03-06 2009-02-17 Quidel Corporation Quantitative lateral flow assays and devices
US20120270238A1 (en) * 2009-10-22 2012-10-25 Moro Ricardo J Peptides That Bind the Alpha-Fetoprotein (AFP) Receptor and Uses Thereof
US20170176457A1 (en) * 2014-03-12 2017-06-22 University Of Virginia Patent Foundation Compositions and methods for treating eye infections and disease
US20200261905A1 (en) * 2016-11-23 2020-08-20 Bio-Rad Laboratories, Inc. Lateral flow assay device
US20180214545A1 (en) * 2017-02-01 2018-08-02 James Madison University Novel methods and reagents for diagnosing sjögren's syndrome

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ANFOSSI L., DI NARDO F., GIOVANNOLI C., PASSINI C., BAGGIANI C.: "Increased sensitivity of lateral flow immunoassay for ochratoxin A through silver enhancement", ANALYTICAL AND BIOANALYTICAL CHEMISTRY, vol. 405, no. 30, 1 December 2013 (2013-12-01), Berlin/Heidelberg, pages 9859 - 9867, XP093103167, ISSN: 1618-2642, DOI: 10.1007/s00216-013-7428-6 *
JIA MIN, E ZHONGBO, ZHAI FEI, BING XIN: "Rapid Multi-Residue Detection Methods for Pesticides and Veterinary Drugs", MOLECULES, vol. 25, no. 16, pages 3590, XP093103170, DOI: 10.3390/molecules25163590 *

Also Published As

Publication number Publication date
WO2023141305A2 (en) 2023-07-27

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