WO2023137936A1 - Cathéter de ventilation capable de réguler automatiquement la pression dans un ballonnet hermétique, et dispositif de raccordement - Google Patents

Cathéter de ventilation capable de réguler automatiquement la pression dans un ballonnet hermétique, et dispositif de raccordement Download PDF

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Publication number
WO2023137936A1
WO2023137936A1 PCT/CN2022/094034 CN2022094034W WO2023137936A1 WO 2023137936 A1 WO2023137936 A1 WO 2023137936A1 CN 2022094034 W CN2022094034 W CN 2022094034W WO 2023137936 A1 WO2023137936 A1 WO 2023137936A1
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WIPO (PCT)
Prior art keywords
pressure
ventilation
sealed
bias
cavity
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PCT/CN2022/094034
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English (en)
Chinese (zh)
Inventor
高宏
高巨
俞卫锋
王志萍
田鸣
胡大伟
黄东晓
熊震天
张隆盛
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高宏
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Publication of WO2023137936A1 publication Critical patent/WO2023137936A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/04—Tracheal tubes
    • A61M16/0434—Cuffs
    • A61M16/044—External cuff pressure control or supply, e.g. synchronisation with respiration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3331—Pressure; Flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3379—Masses, volumes, levels of fluids in reservoirs, flow rates

Definitions

  • the present invention mainly relates to the field of medical treatment, in particular to the field of medical catheters.
  • General anesthesia or ICU patients need to place a tracheal tube into the trachea through the mouth or nose, and then be assisted by an anesthesia machine or a ventilator.
  • an anesthesia machine or a ventilator During mechanical ventilation, the head of the endotracheal tube inserted into the trachea is provided with a sealed capsule.
  • an appropriate amount of gas is filled into the sealed capsule. The gas pressure is higher than the airway pressure during mechanical ventilation. Under the pressure of the sealed capsule on the tracheal mucosa, the blood circulation of the tracheal mucosa is blocked, the blood supply is reduced, or even no blood supply.
  • the gas in the sealed air bag should be evacuated regularly to temporarily restore blood circulation in the airway mucosa.
  • This method requires more manual intervention, which is time-consuming and labor-intensive.
  • the mechanical ventilation leaks seriously, which seriously affects the patient's ventilation effect, affects the patient's oxygenation, and even causes the patient's hypoxia. If the operation is wrong and the gas is not replenished in the sealed air bag in time, it may even lead to extremely serious complications, such as hypoxemia, cardiac arrest, or even death.
  • the present invention provides a sealed airbag automatic pressure-regulating ventilation catheter, which includes a ventilation catheter tube body, and a sealed air bag is provided at the head section of the ventilation catheter tube body.
  • the invention relates to an automatic pressure regulating connection device for a sealed air bag, comprising a bias balance regulator, the bias balance regulator comprising a bias balance pressure regulating cavity and a moving sealing body arranged in the bias pressure balancing pressure regulating cavity, the moving sealing body moves freely in the bias pressure balancing pressure regulating cavity, and the bias pressure balancing pressure regulating cavity is isolated by the moving sealing body into a bag air storage chamber for communicating with the inflation port of a ventilation catheter and a ventilation variable pressure chamber for communicating with a mechanical ventilation breathing circuit; Air-fixed interface, the ventilation and pressure variable chamber is connected with a breathing connecting tube that matches the breathing circuit; a bias elastic body is arranged in the bias pressure balance pressure regulating chamber; during mechanical ventilation, the bias elastic body continuously exerts a force F directed from the ventilation variable pressure chamber to the air storage chamber of the bag to the moving sealing body 43 , so that the gas pressure P in the gas storage chamber of the bag 41 ⁇ Gas pressure in the ventilated variable pressure cavity P 42 .
  • the effective cross-sectional area of the moving sealing body in the bias pressure balance pressure regulating chamber is S, and the (F 43 ⁇ S) ⁇ 10mmHg.
  • the bias pressure balance pressure regulating chamber is set as a cylindrical cavity
  • the moving sealing body is set as a piston body matching the cross section of the cylindrical cavity
  • the biasing elastic body includes compressive elastic body arranged in the ventilation variable pressure chamber or stretched elastic body arranged in the air storage chamber of the bag.
  • the moving sealing body is set as a soft diaphragm sealingly connected with the inner wall of the bias pressure balance pressure regulating chamber
  • the bias elastic body includes an elastic body integrally provided with the soft diaphragm to protrude into the air storage chamber of the bag, a compression elastic body arranged in the ventilation variable pressure chamber for compression, or a stretching elastic body arranged in the air storage chamber of the bag for stretching.
  • an elastic valve inflation port is provided to communicate with the air storage chamber of the bag.
  • the mechanical ventilation breathing circuit includes a ventilation catheter tube body and a breathing connecting tube whose two ends are respectively matched with the ventilation catheter tube body and the breathing threaded tube.
  • the volume of the sealed airbag or the sealed bag of the ventilation catheter is V 2 ; the highest gas pressure in the mechanical ventilation breathing circuit is P max , and the lowest pressure is P min ; the maximum volume of the air storage chamber of the bag is V 41max , and the minimum volume is V 41min ; the (V 41max -V 41min ) ⁇ [(P max /P min )-1] ⁇ V 2 .
  • the outer wall of the cylindrical cavity marks the scale of the pressure generated by the biasing elastic body on the moving sealing body, and the corresponding side wall of the piston body is marked with a reading identification line corresponding to the top of the biasing elastic body.
  • the bias pressure balance pressure regulating chamber is provided with an alarm, and the cylindrical chamber is provided with alarm contacts on both sides of the moving sealing body. When the top of the moving sealing body touches the alarm contacts, the alarm is triggered to alarm.
  • the inspiratory phase time is shorter and the expiratory phase time is longer (generally 1:2).
  • the airway pressure in the inspiratory phase is high (generally not exceeding 25mmHg), and the expiratory phase pressure is low (generally not exceeding 5mmHg);
  • the pressure of the sealed airbag is extremely low, and the blood circulation of the tracheal mucosa in the compressed part of the sealed airbag is hardly affected, which can avoid ischemia of the tracheal mucosa;
  • Fig. 1 is the sectional structure diagram of first kind of embodiment of the present invention
  • Fig. 2 is the cross-sectional structural view of the second embodiment of the present invention
  • Fig. 3 is the cross-sectional structural view of the third embodiment of the present invention.
  • Fig. 4 is the exterior view of the fourth embodiment of the present invention.
  • Fig. 5 is the exterior view of another kind of scheme of the present invention.
  • Fig. 6 is a schematic diagram of the state before the tracheal intubation of the present invention.
  • Fig. 7 is a schematic diagram of the state after successful tracheal intubation of the present invention and before the end of mechanical ventilation extubation;
  • Fig. 8 is a schematic diagram of the state during mechanical ventilation of the present invention.
  • Fig. 9 is a schematic diagram of setting bias voltage difference scale and reading identification line in the present invention.
  • Fig. 10 is a structural schematic diagram of an alarm provided in the bias pressure balancing pressure regulating cavity of the present invention.
  • a sealed balloon automatic pressure-regulating ventilation catheter includes a ventilation catheter body 1, and the ventilation catheter body 1 includes various types of tracheal catheter main tubes, such as single-lumen tracheal tubes, double-lumen tracheal tubes, bronchial occluders, and tracheostomy ventilation tubes, etc.
  • the head section of the ventilation catheter tube body 1 is left in the airway cavity of the patient, and the head section of the ventilation catheter tube body 1 is provided with a sealing air bag 2.
  • the pressure of the sealing air bag 2 is stronger than the airway ventilation pressure, and the sealing air bag 2 is fully in contact with the mucous membrane in the airway cavity, so as to provide ventilation sealing for the mechanically ventilated lung tissue.
  • the inspiratory phase is shorter and the expiratory phase is longer (generally 1:2).
  • the inspiratory phase airway pressure is high (generally not exceeding 25mmHg), and the expiratory phase pressure is low (generally not exceeding 5mmHg).
  • the purpose of the present invention is to adjust the gas volume in the sealed airbag 2 to make the gas pressure in the sealed airbag 2 smaller in the expiratory phase when the time ratio is long and the airway pressure is low, so as to further reduce the pressure of the sealed airbag 2 on the airway mucosa.
  • the airbag 2 compresses the tracheal mucosa in the expiratory phase where the time is relatively long and the pressure is low, the blood circulation is intermittently restored, and the blood circulation that accounts for almost 2/3 of the ventilation time is basically not affected, thereby avoiding ischemia of the tracheal mucosa.
  • the present invention connects the sealed airbag 2 with a bias balance regulator 3, and the function of the bias balance regulator 3 is to keep the gas pressure of the sealed airbag 2 and the gas pressure in the breathing circuit in a non-isobaric balance during mechanical ventilation. That is to say, the gas pressure of the sealed airbag 2 is higher than the gas pressure in the breathing circuit, and the difference between the gas pressure in the sealed airbag 2 and the breathing circuit is optimally controlled between 2mmHg-8mmHg.
  • the airway gas pressure fluctuates between 3mmHg-12mmHg in most patients during mechanical ventilation; the pressure in the expiratory phase is low, mostly 1mmHg-2mmHg, generally not exceeding 3mmHg; the pressure in the inspiratory phase is high, mostly 10mmHg-15mmHg; patients with poor lung compliance rarely exceed 30mmHg.
  • the gas pressure in the sealed airbag 2 (that is, the pressure of the sealed airbag 2 on the airway inner wall mucosa) can be controlled to fluctuate between 5mmHg-18mmHg.
  • the expiratory phase which takes a long time, is relatively low, about 5mmHg, so that the blood circulation of the inner wall of the airway is hardly affected during the expiratory phase, thereby completely avoiding ischemic damage to the inner wall of the airway (mainly the trachea or bronchi).
  • the biasing elastic body 43 continuously exerts force on the moving sealing body 5 from the ventilation variable pressure chamber 42 to the air storage chamber 41 of the bag, and the pressure generated by it on the moving sealing body 5 and directed to the air storage chamber 41 of the bag is P 43 .
  • P airway can ensure that during mechanical ventilation, the pressure of the sealed air bag 2 on the inner wall of the airway is greater than the pressure of the gas in the airway, thereby ensuring the ventilation seal during mechanical ventilation and ensuring the safety of mechanical ventilation.
  • 3P2 (P airway + P43 )
  • P43 the pressure generated by the biasing elastic body 43 on the moving sealing body 5 and directed to the air storage cavity 41 of the bag.
  • the P airway accounts for about 1/3 of the time in the inspiratory phase, which is about 15mmHg-20mmHg, and the patient with poor lung compliance is about 25mmHg-32mmHg; at the same time, the P airway accounts for about 2/3 of the time during the expiratory phase, which is about 2mmHg-5mmHg, and the patient with poor lung compliance is about 5mmHg-8mmHg.
  • the blood supply to the inner wall of the airway is almost Unaffected, it can ensure the safety of the airway inner wall mucosa.
  • the ventilation catheter body 1 is replaced by the ventilation catheter, which is consistent with the existing ventilation catheter.
  • the ventilation catheter includes a single-lumen tracheal tube, a double-lumen tracheal tube, a bronchial occluder, a tracheostomy tube, etc., and the principles thereof will not be repeated here.
  • the effective cross-sectional area of the moving sealing body 5 in the bias pressure balance pressure regulating chamber 4 is S, and the (F 43 ⁇ S) ⁇ 10mmHg. That is to say, when the bias elastic body 43 is deformed to the maximum, the ratio of its elastic force F 43max to the effective cross-sectional area S of the moving sealing body 5 in the bias balance pressure regulating chamber 4 is not greater than 10mmHg, that is, P 43 ⁇ 10mmHg.
  • the ventilation pressure P airway in the patient's airway is relatively low
  • the gas pressure P2 in the sealed airbag 2 is dynamically balanced with the P airway , and is also relatively low
  • the gas in the sealed airbag 2 is relatively inflated
  • the moving sealing body 5 is located in the bias pressure balance pressure regulating chamber 4 and is relatively far away from the side of
  • the amplitude of the reciprocating movement of the moving sealing body 5 in the bias pressure balance pressure regulating cavity 4 is determined by the pressure of the gas filled in the sealed air bag 2 .
  • the bias pressure balance and pressure regulating chamber 4 is set as a cylindrical cavity
  • the moving sealing body 5 is set as a piston body 51 matching the section of the cylindrical cavity
  • the bias elastic body 43 includes a compressed elastic body that is compressed and set in the ventilation variable pressure cavity 42 or a stretched elastic body that is stretched and set in the air storage cavity 41 of the bladder.
  • the moving sealing body 5 is set as a soft diaphragm 52 that is sealed and connected to the inner wall of the bias pressure balance and pressure regulating chamber 41, and the bias elastic body 43 includes an elastic body that is integrated with the soft diaphragm 52 and protrudes into the air storage chamber 41 of the bag, compresses the elastic body that is arranged in the ventilation variable pressure chamber 42, or stretches the elastic body that is arranged in the air storage chamber 41 of the bag.
  • the bias elastic body 43 is a compressed elastic body (spring) arranged in the ventilating and pressure-changing cavity 42. Its working principle is basically the same as that in FIG. Matching can reduce or avoid the influence of frictional force on the reciprocating movement of the piston body 51 in the bias pressure balance pressure regulating cavity 4 .
  • the central reciprocating part of the soft diaphragm 52 should adopt hard light-duty materials and be fixedly connected with the spring; the peripheral parts of the soft diaphragm 52 should adopt non-elastic soft materials, so as to avoid interfering with the effect of the P 43 due to the elastic deformation of the soft diaphragm 52.
  • the biasing elastic body 43 is a stretching elastic body stretched and arranged in the gas storage chamber 41 of the bladder, its working principle is the same as that in FIG. 2 , and will not be repeated here.
  • the biasing elastic body 43 is an elastic body with protrusions extending into the air storage cavity 41 of the bag.
  • the force F 43 directed to the gas storage cavity 41 of the bag can reach the gas pressure P 43 acting in the gas storage cavity 41 of the bag during mechanical ventilation, so that the gas pressure P 41 in the gas storage cavity 41 ⁇ the gas pressure P 42 in the ventilation variable pressure cavity 42 .
  • an elastic valve inflation port 7 is provided to communicate with the bag air storage chamber 41 .
  • the syringe Before endotracheal intubation, it is necessary to connect the syringe to the inflation port 7 of the elastic valve, and discharge the gas in the sealing air bag 2 of the ventilation catheter body 1 or the sealing bag of the ventilation catheter, so that the sealing air bag 2 or the sealing bag membrane body is closely attached to the body 1 of the ventilation catheter or the head section of the ventilation catheter, so as to reduce the maximum outer diameter of the intubation and reduce the friction damage to the glottis and airway at this part.
  • the mechanical ventilation breathing circuit includes a ventilation catheter tube body 1 and a breathing connecting tube 8 whose two ends are respectively matched with the ventilation catheter tube body 1 and the breathing threaded tube.
  • a ventilation catheter tube body 1 and a breathing connecting tube 8 whose two ends are respectively matched with the ventilation catheter tube body 1 and the breathing threaded tube.
  • the ventilation variable pressure chamber 42 is directly communicated with the inner cavity of the ventilation catheter tube body 1;
  • the breathing connecting tube 8 is very common in mechanical ventilation, and is used to connect the front and rear segments of the breathing pipeline, and its two ends have fixed calibers, which will not be repeated here.
  • the volume of the sealing air bag 2 or the sealing bag of the ventilation catheter is V 2 .
  • the volume V2 of the sealed air bag 2 or ventilation catheter sealing bag refers to the sum of the internal volume of the sealing air bag 2 or ventilation catheter sealing bag and the volume of the pipeline connected to the bias balance regulator 3 .
  • the smaller ventilator of model, its V 2 volume is smaller, and the implementation difficulty of the present invention is smaller;
  • the larger ventilator of model, its V 2 Volume is bigger, and the implementation difficulty of the present invention is bigger;
  • the highest gas pressure in the mechanical ventilation breathing circuit is P max , and the lowest pressure is P min .
  • the gas pressure in the mechanical ventilation breathing circuit is the airway pressure of the patient during mechanical ventilation. It is higher during the inspiratory phase, generally below 15mmHg for normal people, and may be higher for special patients, generally not exceeding 30mmHg. Here we take its limit value and take the highest adjustable value of the safety pressure valve of the anesthesia machine as 70mmHg.
  • the bag gas storage chamber 41 is actually the cavity of the bias balance pressure regulating chamber 4 on the side of the moving sealing body 5 adjacent to the sealed air bag 2 or the sealed bag.
  • Inspiratory phase when airway pressure is higher, moving sealing body 5 moves to sealing air bag 2 or sealing bag, and the gas in bag air storage chamber 41 enters in sealing air bag 2 or sealing bag, and inspiratory end bag gas storage chamber 41 interior gas volume reaches minimum value, is V 41min ;
  • Exhalation phase when airway pressure is low, moving sealing body 5 moves to sealing air bag 2 or sealing bag, and the gas in bag air storage chamber 41 enters in sealing air bag 2 or sealing bag, and in end-expiration bag gas storage chamber 41 The gas volume reaches its maximum value, V 41max .
  • V 41max and V 41min are actually the difference produced by the volume difference of the sealed air bag 2 or the gas in the sealed bag under different pressures; the maximum air pressure in the sealed air bag 2 or the sealed bag is set as P max , and the minimum air pressure is P min , according to Boyle’s law:
  • V 41min is 0; it is a limit state where the volume of the gas storage cavity 41 of the bag is the smallest, then it is deduced that:
  • V 41max ⁇ V 41min [(P max /P min ) ⁇ 1] ⁇ V 2 .
  • the volume of the bias balance pressure regulating chamber 4 needs to be greater than 1.85ml at least, which is easy to do.
  • the gas pressure in the area is related to the altitude. The higher the altitude, the lower the gas pressure.
  • the volume of the bias balance pressure regulating chamber 4 needs to be greater than 3.05ml at least, which is also very easy to do.
  • the gas pressure of the hyperbaric oxygen chamber is 0.2-0.25MPa, that is, 1520-1900mmHg.
  • V 2 20ml
  • P min 1900mmHg
  • the volume of the bias balance pressure regulating chamber 4 needs to be greater than 0.74ml at least, which is also very easy to do. It should only be noted that after entering the hyperbaric oxygen chamber, when the pressure of the oxygen chamber rises, it is necessary to add gas to the sealed air bag 2 or the sealed bag in time to increase the basic gas volume of the sealed air bag 2 or the sealed bag so that the air pressure in the sealed air bag 2 or the sealed bag can adapt to the ambient pressure of the hyperbaric oxygen chamber.
  • the outer wall of the cylindrical cavity marks the scale of the pressure generated by the biasing elastic body 43 on the moving sealing body 5
  • the corresponding side wall of the piston body 51 corresponds to the top of the biasing elastic body 43 to mark the reading identification line.
  • the bias pressure balance pressure regulating chamber 4 is provided with an alarm 44
  • the cylindrical cavity is provided with alarm contacts 45 on both sides of the moving sealing body 5, and when the moving sealing body 5 touches the alarm contact 45, the alarm 44 is triggered to alarm.
  • the alarm contacts 45 are triggered, so that the circuit of the alarm 44 is connected, and the alarm 44 alarms.
  • the doctor fills or draws out an appropriate amount of gas in the sealed air bag 2, adjusts the gas content in the sealed air bag 2 to an appropriate level, and the alarm can be automatically released.
  • the present invention installs a bias pressure balance regulator, sets a moving sealing body in the bias pressure balancing pressure regulating chamber, isolates the bias pressure balancing pressure regulating chamber into a bag air storage chamber connected with the sealed airbag and a ventilation pressure variable chamber connected with the mechanical ventilation breathing circuit, and then sets a bias elastic body in the bias pressure balance pressure regulating chamber to continuously apply a force F 43 directed from the ventilation variable pressure chamber to the bag gas storage chamber on the moving sealing body.
  • During mechanical ventilation make the gas pressure P 41 in the gas storage cavity of the bag ⁇ the gas pressure P 42 in the ventilation variable pressure cavity.
  • the airway mucosa is interrupted to maintain blood circulation during the exhalation phase, so as to avoid compression damage to the airway mucosa.

Abstract

La présente invention concerne un cathéter de ventilation capable de réguler automatiquement la pression dans un ballonnet hermétique, et un dispositif de raccordement. Le cathéter de ventilation comprend un corps de cathéter de ventilation (1) ayant un segment avant pourvu d'un ballonnet hermétique (2), un dispositif de réglage de l'équilibre de la pression (3) étant en communication avec le ballonnet hermétique (2), et un tuyau de communication étant en communication avec le dispositif de réglage de l'équilibre de la pression (3) et avec un circuit respiratoire. Pendant la ventilation mécanique, le gaz dans le circuit respiratoire ajuste automatiquement la pression du gaz dans le ballonnet hermétique (2) au moyen du dispositif de réglage de l'équilibre de la pression (3), de sorte que la pression du gaz dans le ballonnet hermétique (2) est supérieure à la pression du gaz dans le circuit respiratoire, la différence de pression étant inférieure à 10 mmHg. La pression dans le ballonnet hermétique (2) du cathéter de ventilation change de manière périodique et synchronisée avec la pression des voies aériennes pendant la ventilation mécanique, de sorte que la pression du gaz dans le ballonnet hermétique (2) est relativement faible pendant la phase expiratoire avec une faible pression des voies aériennes en ventilation mécanique, et que la circulation sanguine de la muqueuse trachéale est périodiquement rétablie pour éviter les lésions de cette dernière.
PCT/CN2022/094034 2022-01-24 2022-05-20 Cathéter de ventilation capable de réguler automatiquement la pression dans un ballonnet hermétique, et dispositif de raccordement WO2023137936A1 (fr)

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CN202210080092.3 2022-01-24
CN202210080092.3A CN114432558B (zh) 2022-01-24 2022-01-24 一种密封气囊自动调压通气导管及连接装置

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Publication number Priority date Publication date Assignee Title
CN114432558B (zh) * 2022-01-24 2023-09-22 无锡圣诺亚科技有限公司 一种密封气囊自动调压通气导管及连接装置
CN115252994A (zh) * 2022-08-10 2022-11-01 江培颜 与呼吸机同步自动调节气管导管套囊压力的方法及装置

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US4501273A (en) * 1982-09-30 1985-02-26 Mcginnis Gerald E Endotracheal tube with pressure controlled inflatable cuff
US4825862A (en) * 1986-02-14 1989-05-02 Tottori University Pressure regulator for cuff of endotracheal tube with superposition of ventilating pressure variation
CN1559628A (zh) * 2004-02-23 2005-01-05 郑兴国 插管气囊自动充气机
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DE3435900A1 (de) * 1984-09-29 1986-04-10 Siemens AG, 1000 Berlin und 8000 München Einrichtung zum intermittierenden aufblasen eines cuffs fuer ein patienten-beatmungsgeraet
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US4501273A (en) * 1982-09-30 1985-02-26 Mcginnis Gerald E Endotracheal tube with pressure controlled inflatable cuff
US4825862A (en) * 1986-02-14 1989-05-02 Tottori University Pressure regulator for cuff of endotracheal tube with superposition of ventilating pressure variation
CN1559628A (zh) * 2004-02-23 2005-01-05 郑兴国 插管气囊自动充气机
CN101296724A (zh) * 2005-08-24 2008-10-29 呼吸医疗技术有限公司 气管内套管气囊填充的调节
CN114432558A (zh) * 2022-01-24 2022-05-06 无锡圣诺亚科技有限公司 一种密封气囊自动调压通气导管及连接装置

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