WO2023130820A1

WO2023130820A1 - Organ state early warning method and system for multi-parameter monitor

Info

Publication number: WO2023130820A1
Application number: PCT/CN2022/128655
Authority: WO
Inventors: 赵宏杰
Original assignee: 赵宏杰
Priority date: 2022-01-08
Filing date: 2022-10-31
Publication date: 2023-07-13
Also published as: CN115886747A

Abstract

A multi-parameter monitor (1), characterized by comprising temperature sensors (2, 3) placed on a body surface corresponding to organs, for giving an alarm and an early warning for the state of each organ according to dynamic data of body surface temperature of the organs in combination with other parameter data of the monitor (1). The early warning method comprises: threshold setting, and time sequence analysis and early warning; and risk state identification for early warning. Disclosed is a method for selecting body surface temperature feature points corresponding to organs, comprising: receiving real-time and recent meteorological factor data of a location of a user, and giving an early warning for the state of each organ according to the data in combination with parameters. Particularly, the temperature sensors (2, 3) are placed in a precordial region on the body surface of a patient, and used for collecting dynamic temperature of the body surface of the heart, and giving an early warning for myocardial ischemia, infarction and heart failure according to the dynamic temperature in combination with other parameter data.

Description

A multi-parameter monitor organ state early warning method and system

technical field

The invention belongs to the field of medical devices, and relates to a multi-parameter monitor organ state early warning method and system, in particular to a multi-parameter monitor heart state early warning method and system, which is suitable for myocardial ischemia, myocardial infarction, heart failure, etc. surveillance and early warning.

Background technique

Multi-parameter monitor is an important and widely used medical equipment, which has a good alarm function, but the lack of early warning function will delay the treatment of patients, and at the same time, it will also make medical staff lack of predictive preparation for work, resulting in overwork. The object of the present invention is to add an early warning method and function to a multi-parameter monitor.

Among the existing medical equipment, there are two representative ones that have the function of early warning or early detection of diseases, PET-CT and infrared thermal imager. PET-CT adds PET that can reflect metabolism and function to CT that reflects structure, and realizes early detection and early warning of diseases represented by tumors. Long-term continuous use of this kind of equipment will cause serious injury to patients due to huge radiation, and it is not suitable for the scene of monitors. Infrared thermal imaging can also reflect the metabolism and function of the human body, and can be used for early detection and early warning of several diseases. However, the method used by the equipment is to passively absorb the heat radiation of the human body, which requires the subject's part to be continuously exposed, and the equipment also needs to occupy a certain space, which is limited in convenience.

Invented and authorized by Guangzhou Institute of Respiratory Diseases, it is a dual-examination comprehensive diagnostic instrument using infrared thermal image-guided ultrasound, application number CN201220604134.0, authorization announcement number CN203029206U. Specifically disclosed is a dual-examination comprehensive diagnostic instrument utilizing infrared thermal image-guided ultrasound. The diagnostic instrument makes full use of the advantages of infrared thermal imaging technology and ultrasonic detection technology, can obtain and mutually confirm the functional and structural imaging examination results, and quickly and effectively make a more definite diagnosis or early warning of the disease, so that patients can diagnose the disease at an early stage. timely and accurate treatment. "Research on In Vivo Thermal Analysis Modeling Method Based on Human Infrared Images", University of Chinese Academy of Sciences, 2018, the study found that compared with X-ray imaging, infrared thermal imaging is ahead of time in the detection and diagnosis of tumors. The former detects physiological changes in human tissue, while the latter detects morphological changes. In disease, the metabolic changes of tissue cells always precede the morphological changes. The temperature field reflects the metabolic changes of tissue cells, always precedes the morphological changes, so early warning can be given.

The present invention uses a temperature sensor instead of infrared thermal imaging or PET to monitor the temperature of the human body. It realizes non-radiation continuous monitoring and has good convenience at the same time. Since infrared thermal imaging or PET has actually been refined from the overall measurement of the core temperature of the human body to the measurement of the temperature of various organs, and the temperature measurement of the thermometer has not clearly proposed related concepts, so the present invention measures the body surface temperature of each major organ , and given the title of organ body surface temperature.

The invention also proposes a method for selecting measurement feature points. Infrared thermal imaging is used in the screening research of coronary heart disease. Many studies have found that the functional state of the heart is positively correlated with the temperature of the precordial region of the body surface, which can be called feature points, or feature points of heart surface temperature. Compared with other parts of the body surface of the organ, the temperature change of the feature point has a more obvious correlation with the health and disease state of the organ. Infrared thermal imaging studies of other diseases provide support for the selection of body surface temperature feature points of various organs.

Zhang Jidong's "Relevant Research Status and Thinking of Infrared Thermal Imaging Technology in Coronary Heart Disease" and Zheng Yansong's "Application of Thermal Tomography Imaging Technology in the Diagnosis of Coronary Heart Disease" focused on the application of thermal detection technology in coronary heart disease, including early warning.

According to the research of meteorological medicine, the impact of meteorological factors on diseases of different organs and the early warning capabilities are also different. Based on these studies, meteorological medical forecasting software has also been developed to a certain extent. With the improvement of algorithms, the level of early warning is also constantly improving. The development of aerospace technology and communication technology makes it more and more convenient to obtain dynamic meteorological data. Therefore, multi-parameter monitors accept these data, which can realize convenient meteorological medical forecasting in monitoring scenarios. Synthesizing an independent variable data set with organ body surface temperature data will inevitably further improve the level of early warning. It is also in line with the development direction of intelligent multi-parameter monitors.

Contents of the invention

A multi-parameter monitor, which is characterized in that the temperature sensor is placed on the skin on the body surface corresponding to the organ, and the dynamic data of the body surface temperature of the organ is used to alarm and monitor the status of one organ or multiple organs in conjunction with other parameter data of the monitor. Early warning; the method of early warning includes setting the threshold value of the body surface temperature of each organ, using the time series analysis of the body surface temperature of the organ and other parameter data of the monitor for early warning; using the body surface temperature of the organ and other parameter data to identify the risk status for early warning; The temperature sensor is placed on the precordial area of the patient's body surface to collect the body surface temperature of the heart; use the dynamic change of the heart temperature to cooperate with other parameter data to give early warning of myocardial ischemia, infarction, and heart failure; use the dynamic change of the heart temperature , cooperate with other parameter data to give early warning to the status of other organs.

According to a kind of multi-parameter monitor described above, it is characterized in that the selection method of the body surface temperature characteristic points corresponding to each organ, and the infrared thermal imaging map is made for various disease patient populations, and the statistical observation and analysis of certain samples are carried out to screen, The body surface location for heart temperature monitoring is preferably the precordial area, near the nipples on both sides of the fourth intercostal space, the body surface location for lung temperature monitoring is preferably one intercostal space above the nipples on both sides of the fourth intercostal space, and the body surface location for liver temperature monitoring is The surface position is preferably 2 and 3 intercostal spaces down from the right precordial area, and then 1 cm to the right. The body surface position of the kidney temperature monitoring is preferably at the intersection of the second lumbar spinous process outward and the outer edge of the erector spinae on both sides. table skin.

A multi-parameter monitor, characterized in that it includes receiving real-time and near-term meteorological factor data of the user's location, referring to the method of meteorological medical forecasting and early warning, and cooperating with other parameters of the monitor to realize early warning of organ status, and coordinating with organ body surface temperature data. Early warning of organ status.

Description of drawings

Fig. 1 is a structural representation of the present invention

In the figure: 1 multi-parameter monitor, 2 body surface temperature measurement stickers, 3 body surface temperature measurement stickers, 4 receiving meteorological factor data

Detailed ways

An embodiment of the present invention will be described in detail below in conjunction with the accompanying drawings.

The embodiment of the present invention is an embodiment of a multi-parameter monitor applied to heart disease early warning. As shown in Figure 1, an organ status warning system of a multi-parameter monitor is added to a conventional multi-parameter monitor, including a body temperature probe of a temperature sensor, a body surface temperature measurement sticker, a meteorological data receiving component, an early warning display, and an early warning output Components; the software part has increased the early warning related functional modules and the connection part of software and hardware.

The organ state warning method of the multi-parameter monitor of the embodiment, using the above-mentioned multi-parameter monitor, in addition to the conventional method, the body surface temperature measuring patch 2 is pasted on the corresponding body surface of the precordial area, and the temperature is continuously monitored; the receiver 4 Receive environmental meteorological factor data; the alarm and early warning system sets thresholds for organ body surface temperature, conducts quantitative analysis and time series analysis of temperature data sensed by sensors, and identifies abnormal changes in heart body surface temperature data; when heart body surface temperature When it is abnormal, an alarm and early warning will be issued; when the heart surface temperature is accompanied by abnormalities in the ECG signal, heart rate, blood oxygen saturation, blood pressure, respiratory rate parameters and combinations, an alarm and early warning will be issued.

When the monitor was first used, a predetermined threshold and time series analysis model, such as the generalized additive model (GAM) and parameters, were used. With the accumulation of data, the operator of the monitor marked the cardiac state change events and related data, Models used for screening tests can be gradually increased, such as distributed lag non-linear model (Distributed Lag non-linear model, DLNM), artificial neural network model, deep learning model, wavelet analysis, etc.

If the early warning model predicts that a severe myocardial ischemic event will occur one hour later, the medical staff can prepare emergency equipment and medicines in advance, and pay attention to inspections when the time is close to the expected time point. In wards, especially ICU and CCU wards, advance knowledge and orderly arrangements can improve the success rate of treatment.

A general intelligent automatic modeling software module can also be added for automatic modeling to realize the localization and individualization of early warning functions.

The present invention is not limited to the technical means disclosed in the above-mentioned embodiments, and technical solutions composed of any combination, equivalent replacement, and deformation of the above-mentioned technical features all fall within the protection scope of the present invention.

Claims

A multi-parameter monitor, which is characterized in that the temperature sensor is placed on the skin on the body surface corresponding to the organ, and the dynamic data of the body surface temperature of the organ is used to alarm and monitor the status of one organ or multiple organs in conjunction with other parameter data of the monitor. Early warning; the method of early warning includes setting the threshold value of the body surface temperature of each organ, using the time series analysis of the body surface temperature of the organ and other parameter data of the monitor for early warning; using the body surface temperature of the organ and other parameter data to identify the risk status for early warning; The temperature sensor is placed on the precordial area of the patient's body surface to collect the body surface temperature of the heart; use the dynamic change of the heart temperature to cooperate with other parameter data to give early warning of myocardial ischemia, infarction, and heart failure; use the dynamic change of the heart temperature , cooperate with other parameter data to give early warning to the status of other organs.
A multi-parameter monitor according to claim 1, characterized in that the selection method of the body surface temperature characteristic points corresponding to each organ is performed by making infrared thermal imaging pictures for various disease patient populations, and performing statistical observation and analysis of certain samples. For screening, the body surface location for heart temperature monitoring is preferably the precordial region, near the nipples on both sides of the fourth intercostal space, the body surface location for lung temperature monitoring is preferably one intercostal space above the nipples on both sides of the fourth intercostal space, and liver temperature monitoring The body surface position of the right precordial area is preferably 2, 3 intercostal spaces and then 1 cm to the right. The body surface position of the kidney temperature monitoring is preferably the second lumbar spinous process horizontally outward and crossing the outer edge of the erector spinae on both sides. Body surface skin.
A multi-parameter monitor, characterized in that it includes receiving real-time and near-term meteorological factor data of the user's location, referring to the method of meteorological medical forecasting and early warning, and cooperating with other parameters of the monitor to realize early warning of organ status, and coordinating with organ body surface temperature data. Early warning of organ status.