WO2023129027A1 - Dispositif d'échantillonnage d'agents biologiques - Google Patents

Dispositif d'échantillonnage d'agents biologiques Download PDF

Info

Publication number
WO2023129027A1
WO2023129027A1 PCT/TR2022/051499 TR2022051499W WO2023129027A1 WO 2023129027 A1 WO2023129027 A1 WO 2023129027A1 TR 2022051499 W TR2022051499 W TR 2022051499W WO 2023129027 A1 WO2023129027 A1 WO 2023129027A1
Authority
WO
WIPO (PCT)
Prior art keywords
air
filter
sampling
filters
step motor
Prior art date
Application number
PCT/TR2022/051499
Other languages
English (en)
Inventor
Murat Ali YÜLEK
Ahmet KOLUMAN
Ahmet KANAT
Görkem PORTAKAL
Original Assignee
Osti̇m Tekni̇k Üni̇versi̇tesi̇
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Osti̇m Tekni̇k Üni̇versi̇tesi̇ filed Critical Osti̇m Tekni̇k Üni̇versi̇tesi̇
Publication of WO2023129027A1 publication Critical patent/WO2023129027A1/fr

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/22—Devices for withdrawing samples in the gaseous state
    • G01N1/2202—Devices for withdrawing samples in the gaseous state involving separation of sample components during sampling
    • G01N1/2205—Devices for withdrawing samples in the gaseous state involving separation of sample components during sampling with filters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/22—Devices for withdrawing samples in the gaseous state
    • G01N1/2202—Devices for withdrawing samples in the gaseous state involving separation of sample components during sampling
    • G01N2001/222—Other features
    • G01N2001/2223—Other features aerosol sampling devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/22—Devices for withdrawing samples in the gaseous state
    • G01N2001/2285—Details of probe structures
    • G01N2001/2288—Filter arrangements

Definitions

  • the invention relates to an improved sampling device for biological agents such as bacteria and/or viruses in the air and/or respirable dust and/or particles in the air and/or metals in the air and/or mold spores and/or allergens and/or asbestos fibers.
  • biological agents such as bacteria and/or viruses in the air and/or respirable dust and/or particles in the air and/or metals in the air and/or mold spores and/or allergens and/or asbestos fibers.
  • sampling of biological warfare agents from the air has become more and more valuable.
  • Existing sampling devices are generally designed for two different purposes, which are particle size control and microbiological contamination control. With said controls, sampling can be carried out in a stationary manner in a certain area, or sampling can also be carried out with portable mobile devices.
  • devices were used to sample at a lower flow rate per minute, but today’s current devices can sample 2-3 times faster per minute than in the past.
  • the data received from the devices of today’s technology are stored on such devices and the received data can be transferred to another electronic medium by means of a flash memory.
  • microbiological air sampling devices the traceability and control processes of the devices have become easier.
  • air sampling is carried out by impinging the air on a fluid, thereby trapping the bacteria in the fluid.
  • the air is collected in the petri dish by impinging on the petri dish.
  • TW201115131A in the state of the art describes an air sampling system that uses air thrust for air pollution in large-area environments. Said system calculates the sampling rate and relative position.
  • TW201400798A in the state of the art describes a particle detection system that draws air. Said device has a large number of holes and performs sampling.
  • CN110241015A in the state of the art describes an air microorganism detection device, which is compartmentalized and contains a fluid. This fluid increases the adhesion of the microorganisms and ensures a stronger adherence.
  • Another document no. CN209432548U in the state of the art describes a positive and negative pressure device comprising a sampling tube. Said document also describes an electromagnetic valve assembly for sampling.
  • WO9014437A1 in the state of the art describes a device for the detection of harmful particulate matter and harmful bacteria such as legionella. Said document also mentions that the device works on the principle of forcing the air for sampling. It is also explained that analyzed harmful organisms and substances such as particles, bacteria, etc. are transferred to the fluid. The invention therefore is fluidbased.
  • Another document no. CN 102311917A in the state of the art describes a system for collecting harmful bacteria by preparing a fluid medium. Therefore, the system in this invention is also fluid-based.
  • Another document no. CN206872829U in the state of the art describes a device that detects microorganisms for longer survival and contains granules and dust suitable for the environment in which it is to be located. Said device allows obtaining a large number of biological samples.
  • a device comprising a filter assembly for sampling biological agents such as bacteria and/or viruses in the air and/or respirable dust and/or particles in the air and/or metals in the air and/or mold spores and/or allergens and/or asbestos fibers by passing air through it.
  • biological agents such as bacteria and/or viruses in the air and/or respirable dust and/or particles in the air and/or metals in the air and/or mold spores and/or allergens and/or asbestos fibers by passing air through it.
  • UAVs Unmanned Aerial Vehicles
  • ground vehicles was not discussed.
  • bacterial damages are possible with the current techniques due to the contact of the person with the bacteria in the system for impingement on the petri dish.
  • the sampling must be done without damaging the bacteria. Therefore, the possibility of bacterial damages is higher in the prior art.
  • the fluid trapping system used in the present art can lead to oxygen stress. It is therefore necessary to develop systems that turn the disadvantages listed in the state of the art into advantages.
  • the object of the invention is to manufacture a sampling device comprising a filter assembly for sampling biological agents such as bacteria and/or viruses in the air and/or respirable dust and/or particles in the air and/or metals in the air and/or mold spores and/or allergens and/or asbestos fibers by passing air through it.
  • the air is passed through a completely specialized filter, thereby sampling the bacteria.
  • the device according to the invention can be easily adapted to unmanned aerial and ground vehicles with a different sampling technique. Furthermore, the device has a high flow rate and performs detection especially for biological warfare agents with a technique that intensifies the sampling surface. The collection speed of the device is high, allowing biological agents to penetrate the filter intensively, thus ensuring a more efficient sampling. Description of the drawings
  • Fig. 1 is an isometric view of the device.
  • Fig. 2 is a block diagram of the control part.
  • Fig. 3 is a top view of the device.
  • Fig. 4 is a front view of the device.
  • Fig. 5 is a rear view of the device.
  • Fig. 6 is a side view of the device.
  • Fig. 7 is a bottom view of the device.
  • Fig. 8 is an exploded view of the filter part.
  • Fig. 9 is a side view of the filter part.
  • Fig. 10 is a large-scale view of the electrodes contained in the filter part.
  • Fig. 11 is a large-scale view of the electrode.
  • Fig. 12 is a view of the position and order of the filters replaced by the step motor in the device.
  • the device (1) for sampling biological agents such as bacteria and/or viruses in the air and/or respirable dust and/or particles in the air and/or metals in the air and/or mold spores and/or allergens and/or asbestos fibers by passing air through it, comprising at least one air inlet part (1.1), at least one filter and control part (1.2), at least one exhaust part (1.3) and/or at least one connection point (1.4) providing connection to an unmanned aerial/ground vehicle or any mobile/stationary vehicle and at least one energy storage unit (1.5).
  • the connection points (1.4) on the top of the device (1) are 4 in number to be connected to the unmanned aerial and ground vehicle.
  • the air inlet part (1.1) comprises at least one channel (1.1.1) to direct the air flow to a filter part (1.2.1). Said channels (1.1.1) transfer the air to the filter part (1.2.1).
  • the filter and control part (1.2) comprises at least one filter part (1.2.1) and at least one control part (1.22).
  • the aforementioned filter part (1.2.1) comprises at least one filter (1.2.1.1) for collecting the pathogens in the air, at least one electrode (1.2.1.2) preferably positioned in the center of the filter part (1.2.1) and at least one step motor (1.2.1.3) for replacing the filters
  • the filter part (1.2.1.1) is in a circular form and the filters (1.2.1.1) and other components of the filter part (1.2.1.1) are mounted to the filter part (1.2.1.1) sequentially.
  • the filters (1.2.1.1) used in the preferred embodiment of the invention are polycarbonate filters having a diameter of 37 mm and a pore size of 0.2 pm. Said filter
  • (1.2.1.1) will be used for sampling biological agents such as bacteria and viruses, as well as respirable dust, particles in the air, metals in the air, mold spores, allergens and asbestos fibers.
  • the electrodes (1.2.1.2) are 2 in number to be positioned at the top and bottom of the filter (1.2.1.1), and the electrical decontamination of the filters (1.2.1.1) will be achieved by applying electrical energy to the filter (1.2.1.1) located between the electrodes (1.2.1.2), thereby creating a strong electric field between the electrodes (1.2.1.2). In this way, the filters are decontaminated after use.
  • the electrodes (1.2.1.2) are located in the chamber (or cartridge) contained in the filter part (1.2.1.1) for decontamination. In other words, said chambers contain electrodes (1.2.1.2).
  • the electrodes (1.2.1.2) are electrically connected to the control unit for the application of an electric field.
  • the exhaust part (1.3) comprises at least one air vacuum motor (1.3.1) for sending the air flow more intensively to the filters (1.2.1.1).
  • the air flow passing through the filter (1.2.1.1) is discharged from the air exhaust part (1.3) more easily through the aforementioned air vacuum motor (1.3.1).
  • the control part (1.2.2) comprises at least one control unit (1.2.2.1) to enable remote control of the device and to transmit the stored data to the user via a communication unit (1.2.2.2), at least one communication unit (1.2.2.2) that provides communication between the user and the device (1), at least one data storage unit (1.2.2.3) that stores the data and at least one screen (1.2.2.4) that allows the data to be displayed.
  • the control unit (1.2.2.1) of the control part (1.2.2) on the device (1) drives the step motor (1.2.1.3) in the filter part (1.2.1) to replace the filters (1.2.1.1) respectively at the desired time.
  • the filter part (1.2.1) therefore comprises at least one step motor (1.2.1.3).
  • the step motor (1.2.1.3) angularly rotates the filters (1.2.1.1), placing the unused filter (1.2.1.1) in the air inlet part (1.1).
  • the used filters (1.2.1.1) are kept in a closed area in the side part.
  • the control unit (1.2.2.1) drives the air vacuum motor (1.3.1) for as long as the device (1) is actively running. For electrical decontamination, the electrodes (1.2.1.2) connected to the card can be activated on demand.
  • the device (1) can be controlled remotely.
  • the communication unit (1.2.2.2) on the electronic card contained in the control unit (1.2.2.1) provides long-range remote control.
  • the filter (1.2.1.1) set can be replaced automatically by remote control.
  • the control unit (1.2.2) activates the step motor (1.2.1.3) to replace the filter (1.2.1.1) set, the old filter (1.2.1.1) is removed and the new filter (1.2.1.1) is positioned in the air inlet part (1.1).
  • the operating time of the device (1) is displayed to the user over an electronic device utilized by the user through communication units (1.2.2.2).
  • at least one fan connected to the air vacuum motor (1.3.1) is capable of withstanding high speeds.
  • the motor speed can be operated at the desired speed.
  • control unit (1.2.2.1) enables remote control of the device (1) and transmits the data stored in a data storage unit (1.2.2.3) to the user via a communication unit (1.2.2.2) and drives the step motor (1.2.1.3) in the filter part (1.2.1) to replace the filters (1.2.1.1) respectively at the desired time and enables the step motor (1.2.1.3) to angularly remove the old filter (1.2.1.1) and position the unused filter
  • step motor (1.2.1.1) in the air inlet part (1.1) and thus remotely activates/deactivates the step motor (1.2.1.3) to perform said functions.
  • the filter part (1.2.1) can be obtained from cellulose-based and/or nonwoven technological products and/or metals.
  • the device (1) is made of an aluminum profile and/or rigid PLA plastic for light weight and durability.
  • the device (1) is designed to block the air in accordance with aerodynamics.
  • the filter part (1.2.1) of the device (1) according to the invention will enable a more reliable sampling. Thanks to the device (1) according to the invention, air sampling in the desired environment can be performed with unmanned aerial and ground vehicles without endangering health in areas where biodefense is applied or suspected to be applied. There is no risk of infection thanks to the filter part (1.2.1) used. After the filters
  • the device (1) operates with filtration in contrast to the present art. All microorganisms accumulated in the filter
  • the device (1) can be easily grown on different growth cultures, and bacterial damage is reduced compared to the system for impingement on the petri dish. At the same time, the oxygen stress that can occur in the fluid trapping system in the present art will be avoided.
  • the device (1) according to the invention is developed to provide air sampling and is applicable to the industry for use in the defense industry, microbiology laboratories, clean rooms and hospitals. Chemical, Biological, Radiological and Nuclear (CBRN) units can be used for sampling in emergencies.
  • CBRN Chemical, Biological, Radiological and Nuclear

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Filtering Of Dispersed Particles In Gases (AREA)

Abstract

L'invention concerne un dispositif (1) d'échantillonnage par passage d'air d'agents biologiques tels que des bactéries et/ou des virus dans l'air et/ou des poussières inhalables et/ou des particules dans l'air et/ou des métaux dans l'air et/ou des spores de moisissure et/ou des allergènes et/ou des fibres d'amiante, comprenant : au moins une partie d'entrée d'air (1.1), au moins une partie d'échappement (1.3) comportant au moins un moteur d'aspiration d'air (1. 3.1), et/ou au moins un point de raccordement (1.4) permettant le raccordement à un véhicule aérien ou terrestre sans pilote ou à tout véhicule mobile ou stationnaire et au moins une unité de stockage d'énergie (1.5) ; et au moins une partie filtre et commande (1.2) comportant au moins une partie filtre (1.2.1) et au moins une partie commande (1.2.2) pour effectuer ledit échantillonnage.
PCT/TR2022/051499 2021-12-31 2022-12-14 Dispositif d'échantillonnage d'agents biologiques WO2023129027A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
TR2021/022152A TR2021022152A2 (tr) 2021-12-31 2021-12-31 Bi̇yoloji̇k ajanlara yöneli̇k bi̇r örneklem ci̇hazi
TR2021/022152 2021-12-31

Publications (1)

Publication Number Publication Date
WO2023129027A1 true WO2023129027A1 (fr) 2023-07-06

Family

ID=85117169

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/TR2022/051499 WO2023129027A1 (fr) 2021-12-31 2022-12-14 Dispositif d'échantillonnage d'agents biologiques

Country Status (2)

Country Link
TR (1) TR2021022152A2 (fr)
WO (1) WO2023129027A1 (fr)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6245132B1 (en) * 1999-03-22 2001-06-12 Environmental Elements Corp. Air filter with combined enhanced collection efficiency and surface sterilization
CN211927422U (zh) * 2020-03-31 2020-11-13 西北核技术研究院 一种可实现自动取样的气溶胶样品取样装置

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6245132B1 (en) * 1999-03-22 2001-06-12 Environmental Elements Corp. Air filter with combined enhanced collection efficiency and surface sterilization
CN211927422U (zh) * 2020-03-31 2020-11-13 西北核技术研究院 一种可实现自动取样的气溶胶样品取样装置

Also Published As

Publication number Publication date
TR2021022152A2 (tr) 2022-01-21

Similar Documents

Publication Publication Date Title
US7100461B2 (en) Portable contaminant sampling system
US20210396630A1 (en) Airborne agent collectors, methods, systems and devices for monitoring airborne agents
JP4671058B2 (ja) 生物学的粒子を収集する方法、チップ、装置、及びシステム
US6955075B2 (en) Portable liquid collection electrostatic precipitator
US6565638B1 (en) Portable air-borne bacteria sampler
KR20160071392A (ko) 부유 미생물 샘플러
EP1730518A2 (fr) Procede, puce, dispositif et systeme integre pour la detection de particules biologiques
US6960244B2 (en) System and method for removing contaminates from the air in a mail-sorting room
JP2005523810A (ja) 流体清浄
CN112236093A (zh) 过滤系统、设备和方法
EP1867346A1 (fr) Dispositif de traitement de l'air et procédé de traitement d'un gaz
US9446159B2 (en) Flow cytometer biosafety hood and systems including the same
EP3319644A1 (fr) Dispositif de décontamination
WO2023129027A1 (fr) Dispositif d'échantillonnage d'agents biologiques
US20070107538A1 (en) Biobriefcase aerosol collector heater
US20070107537A1 (en) Biobriefcase electrostatic aerosol collector
EP3134720B1 (fr) Cartouche d'étanchéité à bande coulissante permettant de fermer hermétiquement une chambre de manipulation d'échantillon à cytomètre à flux
CN216778853U (zh) 一种自带滤芯的新型移液枪
US20030131654A1 (en) Method and apparatus for monitoring building air flow
US7789246B1 (en) Biological sample collector
CN105266418A (zh) 一种危险化学品存放柜
US20040191113A1 (en) Spore collection and elimination apparatus and method
CN117897215A (zh) 具有可移除的入口组件的气溶胶收集器
Whitlock et al. Microbial Mayhem: Microbial Growth Potential in CO2 Removal Systems Designed for Long-Duration Spaceflight
Rubino Decontamination of indoor air to reduce the risk of airborne infections: Studies on survival and inactivation of airborne pathogens using an aerobiology chamber

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 22917028

Country of ref document: EP

Kind code of ref document: A1