WO2023123628A1 - Multi-dimensional signal control system and method - Google Patents

Multi-dimensional signal control system and method Download PDF

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WO2023123628A1
WO2023123628A1 PCT/CN2022/076498 CN2022076498W WO2023123628A1 WO 2023123628 A1 WO2023123628 A1 WO 2023123628A1 CN 2022076498 W CN2022076498 W CN 2022076498W WO 2023123628 A1 WO2023123628 A1 WO 2023123628A1
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signal
dimensional
eye movement
reward
eye
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PCT/CN2022/076498
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French (fr)
Chinese (zh)
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姚洋
徐婵
王龙飞
詹阳
周晖晖
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中国科学院深圳先进技术研究院
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/40Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4076Diagnosing or monitoring particular conditions of the nervous system
    • A61B5/4088Diagnosing of monitoring cognitive diseases, e.g. Alzheimer, prion diseases or dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/113Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for determining or recording eye movement
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/369Electroencephalography [EEG]
    • A61B5/377Electroencephalography [EEG] using evoked responses
    • A61B5/378Visual stimuli
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M2021/0005Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
    • A61M2021/0044Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus by the sight sense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M2021/0005Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
    • A61M2021/0044Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus by the sight sense
    • A61M2021/005Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus by the sight sense images, e.g. video
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P90/00Enabling technologies with a potential contribution to greenhouse gas [GHG] emissions mitigation
    • Y02P90/02Total factory control, e.g. smart factories, flexible manufacturing systems [FMS] or integrated manufacturing systems [IMS]

Definitions

  • the embodiments of the present application relate to the technical field of visual cognition detection and control, for example, to a multi-dimensional signal control system and method.
  • Non-human primates are ideal model animals for studying brain cognitive function and exploring the neural network of brain diseases.
  • macaques have always been the main model animals for vision-based brain cognition research due to their visual system very similar to that of humans and their high intelligence.
  • Related technologies Based on the visual cognition research of macaques, a large amount of histological, behavioral and electrophysiological experimental data have been accumulated, which has laid a good foundation for future research on the analysis of brain functional circuits. Vision-based attention, learning and memory, decision-making, emotional perception and regulation are important components of higher brain cognitive functions, and abnormal visual cognitive functions are also closely related to a variety of brain diseases.
  • the visual system mainly receives visual stimuli.
  • the structure and function of the visual system are also gradually evolved in the process of adapting to the complex natural environment. Therefore, visual stimuli that can be precisely controlled and that are similar to natural environments are crucial for resolving visual cognitive brain functions.
  • the embodiment of the present application provides a multi-dimensional signal control system and method to realize the cognitive function test in the three-dimensional environment and improve the test signal dimension of the cognitive function test.
  • the embodiment of the present application provides a multi-dimensional signal control system, including: a multi-dimensional signal control device, a three-dimensional visual stimulation device, an eye movement detection device and an eye movement signal processing device, wherein:
  • the three-dimensional visual stimulation device is configured to generate a three-dimensional visual stimulation signal based on a preloaded three-dimensional visual stimulation perception task, and display the three-dimensional visual stimulation signal to the eyes of the examinee, so that the eyes of the examinee follow the displayed three-dimensional Visual stimuli signal movement;
  • the eye movement detection device is configured to detect the eye detection information of the inspected party, and send the eye detection information to the multi-dimensional signal control device;
  • the multi-dimensional signal control device is configured to generate eye movement information according to the eye detection information, and send the eye movement information to the eye movement signal processing device;
  • the eye movement signal processing device is configured to generate a feedback signal according to the eye movement information, and send the feedback signal to the multi-dimensional signal control device;
  • the multi-dimensional signal control device is also configured to perform the operation corresponding to the feedback signal.
  • the embodiment of the present application also provides a multi-dimensional signal control method, which is executed by the multi-dimensional signal control system provided in any embodiment of the present application, including:
  • the 3D visual stimulation device generates 3D visual stimulation signals according to the preloaded 3D visual stimulation perception tasks, and displays the 3D visual stimulation signals to the eyes of the inspected party, so that the inspected party's eyes follow the displayed 3D visual stimulation signals.
  • the eye movement detection device detects the eye detection information of the inspected party, and sends the eye detection information to the multi-dimensional signal control device;
  • the multi-dimensional signal control device generates eye movement information according to the eye detection information, and sends the eye movement information to the eye movement signal processing device;
  • the eye movement signal processing device generates a feedback signal according to the eye movement information, and sends the feedback signal to the multi-dimensional signal control device;
  • the multi-dimensional signal control device executes the operation corresponding to the feedback signal.
  • FIG. 1 is a schematic structural diagram of a multi-dimensional signal control system provided in Embodiment 1 of the present application;
  • FIG. 2 is a schematic structural diagram of a computer device provided in Embodiment 1 of the present application.
  • FIG. 3 is a flow chart of a multi-dimensional signal control method provided in Embodiment 2 of the present application.
  • the cognitive tasks of related technologies are realized based on two-dimensional visual stimuli, which are somewhat different from the three-dimensional visual environment in the natural environment. Therefore, how to realize the cognitive function test in the three-dimensional environment is a technical problem to be solved urgently.
  • FIG. 1 is a schematic structural diagram of a multi-dimensional signal control system provided in Embodiment 1 of the present application.
  • the multi-dimensional signal control system provided in this embodiment is applicable to situations where primates are controlled based on multi-dimensional control signals.
  • the multi-dimensional signal control system includes a multi-dimensional signal control device 10, a three-dimensional visual stimulation device 20, an eye movement detection device 30 and an eye movement signal processing device 40, wherein:
  • the three-dimensional visual stimulation device 20 is configured to generate a three-dimensional visual stimulation signal based on a preloaded three-dimensional visual stimulation perception task, and present the three-dimensional visual stimulation signal to the subject's eyes, so that the subject's eyes follow the displayed Three-dimensional visual stimuli signal movement;
  • the eye movement detection device 30 is configured to detect the eye detection information of the inspected party, and send the eye detection information to the multi-dimensional signal control device 10;
  • the multi-dimensional signal control device 10 is configured to generate eye movement information according to the eye detection information, and send the eye movement information to the eye movement signal processing device 40;
  • the eye movement signal processing device 40 is configured to generate a feedback signal according to the eye movement information, and send the feedback signal to the multi-dimensional signal control device 10;
  • the multi-dimensional signal control device 10 is further configured to perform an operation corresponding to the feedback signal.
  • the three-dimensional visual stimulation device, the eye movement detection device, and the eye movement signal processing device are all communicatively connected to the multi-dimensional signal control device.
  • the multi-dimensional signal control device is the core of the multi-dimensional signal control system, and coordinates the interaction with the 3D visual stimulation device and the eye movement detection device to realize the input and interaction of the 3D visual stimulation device and the eye movement detection device.
  • the output control can complete operations such as eye movement signal transmission, reward signal transmission, and event coding signal transmission.
  • the three-dimensional visual stimulation sensory task is developed in the development tool in advance, and the developed three-dimensional visual stimulation perception task is imported into the three-dimensional visual stimulation device, and the three-dimensional visual stimulation device stores the three-dimensional visual stimulation perception task, and the three-dimensional visual stimulation can be performed.
  • the three-dimensional visual stimulation equipment consists of two parts: a control system and a display device. Among them, the control system is used for operations such as storing, switching, and transmitting three-dimensional visual stimulation perception tasks, and the display device can be a head-mounted 3D display screen for displaying three-dimensional visual stimulation signals.
  • the 3D visual stimulation device generates 3D visual stimulation signals based on the preloaded 3D visual stimulation perception tasks for display, the eyes of the examinee move with the displayed 3D visual stimulation signals, and the eye movement detection equipment detects the motion of the examinee.
  • Eye movement get eye detection information, and send the eye detection information to the multi-dimensional signal control device
  • the multi-dimensional signal control device generates eye movement information according to the eye detection information, and sends the eye movement information to the eye movement signal
  • the processing device the eye movement signal processing device generates a feedback signal according to the eye movement information, and sends the feedback signal to the multi-dimensional signal control device, so that the multi-dimensional signal control device performs the operation corresponding to the feedback signal to complete the three-dimensional visual cognition task.
  • the feedback signal can be task execution information, such as task execution completion or task execution incomplete, and it can also be a reward signal after task execution is completed.
  • the display device in the three-dimensional visual stimulation device may adopt a related technology virtual reality (Virtual Reality, VR) and/or augmented reality (Augmented Reality, AR) device.
  • VR Virtual Reality
  • AR Augmented Reality
  • a 3D visual stimulus perception task can be pre-developed based on Unity3D.
  • Unity3D supports multiple mainstream platforms at the same time, which greatly reduces the difficulty for developers to release multiple platforms; it also supports scripting languages such as C#, JavaScript, and Boo; it also supports major art resource file formats, which can meet the needs of developers with no development experience.
  • it also provides highly optimized graphics rendering, embedded Mecanim animation system, Shuriken particle system and other functions.
  • the development logic of the three-dimensional visual stimulation perception task is to present the subject (such as a macaque) with a visual cognition task based on three-dimensional visual stimulation, and at the same time collect the subject's eye movement signals.
  • a reward signal can be sent to reward the inspected party when the inspected party successfully completes the task; it can also be used during the completion of the three-dimensional visual stimulus perception task, such as the beginning of the event, the end of the event, the appearance of the visual stimulus, the visual Stimulus types and reward delivery are digitally coded, and task events are marked by digitally coded events.
  • the multi-dimensional signal control device can be developed based on an embedded development board.
  • the embedded development board has strong computing power, flexible development architecture, a sufficient number of digital and analog I/O ports, serial port interrupts, and functions such as timers and counters at the same time, meeting the multi-dimensional requirements of 3D visual cognitive function tests. Functional requirements for signal control equipment.
  • the eye movement detection device may be an eye movement detector (eye tracker).
  • the eye tracker is based on a fast image processing method, uses a high-speed camera to directly collect eye images, and calculates the position of the eyes based on the eye images.
  • the eye tracker may use an eye tracker of related technology. Take SensoMotoric Instrumens iView X High-speed Primate Eye Tracker (SMI Eye Tracker) as an example. Reliable tracking, high temporal and spatial resolution, and easy integration as part of an animal training system.
  • SI Eye Tracker SensoMotoric Instrumens iView X High-speed Primate Eye Tracker
  • the SMI eye tracker can track the dark pupils of one or both eyes, and output the analog voltage of the X and Y directions of the eye position, and the pupil size and other information at the same time.
  • the eye movement signal of the subject is collected by the eye tracker, instead of directly implanting a tracking device into the subject's eye through the eye tracking device built in the 3D helmet or an invasive method.
  • the method is simple to implement and can be directly and effectively observed The status of the party under prosecution.
  • the eye tracker When performing a three-dimensional visual cognitive function test, the eye tracker was placed in front of the macaque, and its position was adjusted so that it could completely track the pupil of the macaque, that is, the white coil wrapped around the dark pupil. Through the control software of the eye tracker, set the hardware parameters of sampling frequency, eye position voltage range, single eye or binocular output. Hardware parameters can be determined according to actual test requirements.
  • the eye detection information is analog voltage information
  • the eye movement information is generated according to the eye detection information, including: performing analog-to-digital conversion on the analog voltage information to obtain eye movement information.
  • the multi-dimensional signal control device is developed based on the STM32 development board, and the eye movement detection device is an eye tracker.
  • the eye movement detection device is an eye tracker.
  • two analog voltage output wires are drawn from the eye tracker port.
  • the two signals are the position of the eye movement.
  • X and Y coordinates, the range can generally be set to -5V ⁇ +5V.
  • ADC Analog-to-Digital Converter
  • the eye detection information in the form of an analog voltage signal first passes through the AD7606 module, and converts the analog voltage in the range of -5V to +5V with 16-bit precision for analog-to-digital conversion. Then, the STM32 development board timer interrupts the data sampling of the AD7606 module, packs the data to obtain eye movement information, and outputs the data to the 3D visual stimulation device through the USB serial port communication.
  • the multi-dimensional signal control system includes: multi-dimensional signal control equipment, three-dimensional visual stimulation equipment, eye movement detection equipment and eye movement signal processing equipment, wherein: the three-dimensional visual stimulation equipment is set based on preloaded three-dimensional The visual stimulation perception task generates a three-dimensional visual stimulation signal, and displays the three-dimensional visual stimulation signal to the eyes of the inspected party, so that the inspected party's eyes move with the displayed three-dimensional visual stimulation signal; the eye movement detection device is set In order to detect the eye detection information of the inspected party, and send the eye detection information to the multi-dimensional signal control device; the multi-dimensional signal control device is set to generate eye movement information according to the eye detection information, and send the eye movement information to to the eye movement signal processing device; the eye movement signal processing device is also set to generate a feedback signal according to the eye movement information, and sends the feedback signal to the multi-dimensional signal control device; the multi-dimensional signal control device is also set to execute the feedback signal corresponding operate.
  • the cognitive function test improves the test signal dimension of the cognitive function test.
  • generating the feedback signal according to the eye movement information includes: judging whether the three-dimensional visual stimulation perception task is completed according to the eye movement information; when the three-dimensional visual stimulation perception task is completed, generating a reward signal as the feedback signal .
  • the feedback signal generated by the 3D visual stimulation device may be a reward signal, which rewards the inspected party when completing the 3D visual stimulation perception task, and positively promotes the completion of the 3D visual stimulation perception task.
  • the three-dimensional visual stimulation signal can be a red sphere
  • the displayed red sphere can be compared with the collected eye detection information to determine whether the subject is staring at the red sphere, and when the subject is staring at the red sphere, It is judged that the three-dimensional visual stimulation perception task is completed, if the subject does not stare at the red sphere, it is judged that the three-dimensional visual stimulation perception task is not completed.
  • the system also includes a reward device; the multi-dimensional signal control device is also set to generate a set level signal according to the reward signal and output it to the reward device; the reward device is set to receive the set level signal Perform reward actions.
  • a reward device is set in the system to complete the reward operation for the inspected party. Taking macaques as the subject of the prosecution as an example, in order to show the macaques that the task is completed correctly or to appease the macaques, they will give grape juice, apple juice and other drinks as rewards.
  • the multi-dimensional signal control device After receiving the reward signal sent by the three-dimensional visual stimulation device, the multi-dimensional signal control device generates a signal with a set level and outputs it to the reward device, so that the reward device performs a reward operation.
  • the set level signal can be set according to actual needs, such as the high level signal can be set as the reward level signal, the low level signal can be set as the stop reward level signal; the low level signal can also be set For reward level signal, set high level signal to stop reward level signal.
  • generating a set level signal according to the reward signal and outputting it to the reward device includes: determining the reward duration according to the reward signal, using the reward duration as the counting period; starting timing, outputting the reward level signal, and When the output time reaches the reward duration, the stop reward level signal is output.
  • the output of the set level signal can be implemented based on a timer. First, determine the duration of the reward according to the set bit value in the reward signal, use the duration of the reward as the counting period of the timer, call the timer initialization, and configure the timer based on the counting period of the timer.
  • the timer function When the multi-dimensional cognitive function test is executed, the timer function is turned on, and the timer starts counting; after the timer starts counting, the reward level signal is output by setting the output port, and the timer counting ends in response to the timer interrupt function , the timer is closed, the interrupt flag is cleared, and the timer interrupt function outputs the stop reward level signal by setting the output port to complete the reward program.
  • the incentive device includes a liquid storage device, a solenoid valve pump and a liquid conduit, one end of the liquid conduit is connected to the liquid storage device, and the reward operation is performed according to the received level signal, including: when receiving the reward level signal, the electromagnetic The valve pump is turned on, and the liquid in the liquid storage device flows out through the liquid conduit; when receiving the stop reward level signal, the electromagnetic valve pump is closed, and the liquid in the liquid storage device stops flowing out.
  • the reward device may be a square box with a solenoid valve pump integrated inside, a liquid conduit arranged above the box, and a power line, conduction control line, and ground line below the box.
  • One end of the liquid conduit is inserted into a measuring bottle (i.e., a liquid storage device) containing fruit juice, and the other end is connected to a small nozzle and put into the mouth of the inspected party.
  • a measuring bottle i.e., a liquid storage device
  • the electromagnetic valve is opened, and the juice flows out along the conduit, and the inspected party is rewarded at this time.
  • the set stop reward voltage is applied to the conduction control line, the electromagnetic valve is closed, and the juice stops flowing out. At this time, the inspected party does not get a reward.
  • the system also includes an electrophysiological signal acquisition device; a three-dimensional visual stimulation device, which is also configured to generate an electrophysiological event trigger signal and send it to the multi-dimensional signal control device when a preset electrophysiological event is detected; the multi-dimensional The signal control device is also configured to process the electrophysiological event trigger signal to obtain the electrophysiological event marker signal, and send the electrophysiological event marker signal to the electrophysiological signal acquisition device; the electrophysiological signal acquisition device is configured to monitor the electrophysiological event The labeled signal is processed to obtain the detection and analysis results.
  • the preset electrophysiological event includes at least one of appearance of visual stimulus, disappearance of visual stimulus, change of presentation position of visual stimulus, and change of presentation depth of visual stimulus.
  • the preset electrophysiological events may also include a visual stimulus set position event and a visual stimulus set depth event.
  • an electrophysiological signal acquisition device is added to collect the electrophysiological event signals during the test.
  • the principle of electrophysiological event marking is: when an electrophysiological event is detected, the Strobe bit is initialized as a high-level signal, and the electrophysiological event is transmitted to 16 digital signal input bits , and then give Strobe a low level, and then quickly give a high level.
  • the multi-dimensional signal control device refreshes the receiving port at a set frequency and reads the value once. In this way, the encoded transmission of an electrophysiological event is successfully completed, and the marker signal of the electrophysiological event can be seen on the control host interface of the multi-dimensional signal control device.
  • the electrophysiological event trigger signal is an electrophysiological event code
  • processing the electrophysiological event trigger signal to obtain an electrophysiological event marker signal includes: converting the encoded value of the electrophysiological event code into a binary value to obtain an electrophysiological event Physiological event marker signals.
  • the electrophysiological event trigger signals can be set in the form of encoding.
  • the transmitted electrophysiological event signal is packaged data, which is a series of arrays with different byte lengths. The data at each position in the array sets its corresponding meaning.
  • the coded value of the electrophysiological event code is converted into a binary value to obtain an electrophysiological event marker signal, which is sequentially assigned to each output port for output. Always keep the output until the next output flush.
  • the three-dimensional visual stimulation equipment, eye movement detection equipment, eye movement signal processing equipment, multi-dimensional signal control equipment, electrophysiological signal acquisition equipment and rewarding devices can all be in the form of general computer equipment Performance.
  • FIG. 2 shows a schematic structural diagram of an exemplary computer device 212 suitable for implementing the embodiments of the present application.
  • the computer device 212 provided by the present application may include: one or more processors or processing units 216 , the system memory 228, the bus 218 connecting different system components (including the system memory 228 and the processing unit 216).
  • the bus 218 represents one or more of several types of bus structures, including a memory bus or memory controller, a peripheral bus, a graphics acceleration port, a processor, or a local bus using any bus structure in various bus structures.
  • These architectures may include, for example, an Industrial Standard Architecture (ISA) bus, a Micro Channel Architecture bus, an Enhanced ISA bus, a Video Electronics Standards Association local bus, and a Peripheral Component Interconnect bus.
  • Computer device 212 may include a variety of computer system readable media. These media can be any available media that can be accessed by computing device 212 and include both volatile and nonvolatile media, removable and non-removable media.
  • System memory 228 may include computer system readable media in the form of volatile memory, such as Random Access Memory (RAM) 230 and/or cache memory 232 .
  • Computer device 212 may further include other removable/non-removable, volatile/nonvolatile computer system storage media.
  • storage system 234 may be used to read from and write to non-removable, non-volatile magnetic media (commonly referred to as a "hard drive”).
  • System memory 228 may also provide disk drives for reading and writing to removable non-volatile disks (such as "floppy disks"), and for removable non-volatile optical disks (such as CD-ROM, DVD-ROM, or other optical media). ) read and write CD-ROM drive. In these cases, each drive may be connected to bus 218 through one or more data media interfaces.
  • the system memory 228 may include at least one program product having a set (eg, at least one) of program modules configured to perform the functions of the embodiments of the present application.
  • Programs/utilities 240 may be stored, for example, in system memory 228 as a set (at least one) of program modules 242, such program modules 242 including an operating system, one or more application programs, other program modules, and program data, which Each or some combination of the examples may include the implementation of a network environment.
  • the program module 242 generally executes the functions and/or methods in the embodiments described in this application.
  • the computer device 212 may also communicate with one or more external devices 214 (e.g., a keyboard, pointing device, display 224, etc.), and with one or more devices that enable a user to interact with the computer device 212, and/or with Any device (eg, network card, modem, etc.) that enables the computing device 212 to communicate with one or more other computing devices. Such communication may occur through input/output (I/O) interface 222 . Also, the computer device 212 can also communicate with one or more networks (eg, a local area network, a wide area network, and/or a public network, such as the Internet) through the network adapter 220 . As shown in FIG.
  • network adapter 220 communicates with other modules of computer device 212 via bus 218 . It should be appreciated that other hardware and/or software modules may also be used in conjunction with computer device 212, including: microcode, device drivers, redundant processing units, external disk drive arrays, disk array systems, tape drives, and data backup storage systems, among others.
  • the processing unit 216 can execute various functional applications and data processing by running at least one of other programs among a plurality of programs stored in the system memory 228 .
  • any of the three-dimensional visual stimulation equipment, eye movement detection equipment, eye movement signal processing equipment, multi-dimensional signal control equipment, electrophysiological signal acquisition equipment and rewarding device may include the general-purpose computer as described above equipment.
  • FIG. 3 is a flow chart of a multi-dimensional signal control method provided in Embodiment 2 of the present application. This embodiment is applicable to the situation of controlling primates based on multi-dimensional control signals. The method is executed by the multi-dimensional signal control system provided in any embodiment of the present application. In this embodiment, explanations of terms that are the same as or corresponding to those in the foregoing embodiments are not repeated here.
  • the method includes:
  • the three-dimensional visual stimulation device generates three-dimensional visual stimulation signals according to the preloaded three-dimensional visual stimulation perception tasks, and displays the three-dimensional visual stimulation signals to the eyes of the examinee, so that the eyes of the examinee follow the displayed three-dimensional vision. Stimulate signal movement.
  • the eye movement detection device detects the eye detection information of the inspected party, and sends the eye detection information to the multi-dimensional signal control device.
  • the multi-dimensional signal control device generates eye movement information according to the eye detection information, and sends the eye movement information to the eye movement signal processing device.
  • the eye movement signal processing device generates a feedback signal according to the eye movement information, and sends the feedback signal to the multi-dimensional signal control device.
  • the multi-dimensional signal control device executes an operation corresponding to the feedback signal.
  • a 3D visual stimulation device is used to generate a 3D visual stimulation signal according to a preloaded 3D visual stimulation perception task, and the 3D visual stimulation signal is displayed to the examinee's eyes, so that the examinee's eyes follow the display.
  • the three-dimensional visual stimulation signal movement the eye movement detection device detects the eye detection information of the inspected party, and sends the eye detection information to the multi-dimensional signal control device; the multi-dimensional signal control device generates eye movement information according to the eye detection information , and send the eye movement information to the eye movement signal processing device; the eye movement signal processing device generates a feedback signal according to the eye movement information, and sends the feedback signal to the multi-dimensional signal control device; the multi-dimensional signal control device executes the feedback signal corresponding to Operation, through the multi-dimensional signal control equipment to realize the information interaction between the three-dimensional visual stimulation equipment and the eye movement detection equipment, realize the cognitive function test in the three-dimensional environment, and improve the test signal dimension of the cognitive function test.
  • generating a feedback signal according to eye movement information includes: judging whether the three-dimensional visual stimulation perception task is completed according to the eye movement information; when the three-dimensional visual stimulation perception task is completed, generating a reward signal as feedback Signal.
  • the system also includes a reward device, and the method also includes:
  • the multi-dimensional signal control device generates a set level signal according to the reward signal and outputs it to the reward device;
  • the reward means performs a reward operation upon receiving the set level signal.
  • a set level signal is generated according to the reward signal and output to the reward device, including:
  • the incentive device includes a liquid storage device, a solenoid valve pump, and a liquid conduit.
  • One end of the liquid conduit is connected to the liquid storage device, and the reward operation is performed according to the received level signal, including:
  • the solenoid valve pump When the reward level signal is received, the solenoid valve pump is turned on, and the liquid in the liquid storage device flows out through the liquid conduit;
  • the solenoid valve pump When receiving the stop incentive level signal, the solenoid valve pump is turned off, and the liquid in the liquid storage device stops flowing out.
  • the eye detection information is analog voltage information
  • the eye movement information is generated according to the eye detection information, including:
  • the system also includes an electrophysiological signal acquisition device, and the method also includes:
  • the three-dimensional visual stimulation device When the three-dimensional visual stimulation device detects a preset electrophysiological event, it generates an electrophysiological event trigger signal and sends it to the multi-dimensional signal control device;
  • the multi-dimensional signal control device processes the electrophysiological event trigger signal to obtain the electrophysiological event marker signal, and sends the electrophysiological event marker signal to the electrophysiological signal acquisition device;
  • the electrophysiological signal acquisition device processes the electrophysiological event marker signal to obtain detection and analysis results.
  • the electrophysiological event trigger signal is an electrophysiological event code
  • the electrophysiological event trigger signal is processed to obtain an electrophysiological event marker signal, including:
  • the encoded value of the electrophysiological event code is converted into a binary value to obtain an electrophysiological event marker signal.
  • the preset electrophysiological events include at least one of appearance of visual stimulus, disappearance of visual stimulus, change of presentation position of visual stimulus, and change of presentation depth of visual stimulus.

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Abstract

A multi-dimensional signal control system and a method. The system comprises: a three-dimensional visual stimulation device (20), configured to generate a three-dimensional visual stimulation signal on the basis of a pre-loaded three-dimensional visual stimulation perception task, and display the three-dimensional visual stimulation signal to the eyes of a subject, so that the eyes of the subject move with the displayed three-dimensional visual stimulation signal; an eye movement detection device (30), configured to detect eye detection information of the subject and send the eye detection information to a multi-dimensional signal control device (10); a multi-dimensional signal control device (10), configured to generate eye movement information according to the eye detection information, and send the eye movement information to an eye movement signal processing device (40); an eye movement signal processing device (40), configured to generate a feedback signal according to the eye movement information, and send the feedback signal to the multi-dimensional signal control device (10), the multi-dimensional signal control device (10) also being configured to execute an operation corresponding to the feedback signal.

Description

多维度信号控制系统和方法Multi-dimensional signal control system and method
本公开要求在2021年12月29日提交中国专利局、申请号为202111644254.3的中国专利申请的优先权,该申请的全部内容通过引用结合在本申请中。This disclosure claims priority to a Chinese patent application with application number 202111644254.3 filed with the China Patent Office on December 29, 2021, the entire contents of which are incorporated herein by reference.
技术领域technical field
本申请实施例涉及视觉认知检测与控制技术领域,例如涉及一种多维度信号控制系统和方法。The embodiments of the present application relate to the technical field of visual cognition detection and control, for example, to a multi-dimensional signal control system and method.
背景技术Background technique
非人灵长类是研究脑认知功能,探索脑疾病神经网络的理想模式动物。在各种灵长类动物中,猕猴由于拥有与人类非常近似的视觉系统以及较高的智力,一直是基于视觉的脑认知研究的主要模式动物。相关技术基于猕猴的视觉认知研究,已经积累了大量的组织学、行为学以及电生理学的实验数据,这为未来脑功能环路解析的研究奠定了良好的基础。基于视觉的注意、学习记忆、决策、情绪感知和调控等是脑高级认知功能的重要组成部分,而视觉认知功能异常也与多种脑疾病密切相关。Non-human primates are ideal model animals for studying brain cognitive function and exploring the neural network of brain diseases. Among various primates, macaques have always been the main model animals for vision-based brain cognition research due to their visual system very similar to that of humans and their high intelligence. Related technologies Based on the visual cognition research of macaques, a large amount of histological, behavioral and electrophysiological experimental data have been accumulated, which has laid a good foundation for future research on the analysis of brain functional circuits. Vision-based attention, learning and memory, decision-making, emotional perception and regulation are important components of higher brain cognitive functions, and abnormal visual cognitive functions are also closely related to a variety of brain diseases.
在自然环境中,视觉系统主要接受视觉刺激,大脑为满足自然环境的需要,其视觉系统的结构和功能也在适应复杂自然环境的过程中逐渐进化形成。因此,可以精确控制的、与自然环境相似的视觉刺激,对解析视觉认知脑功能是至关重要的。In the natural environment, the visual system mainly receives visual stimuli. In order to meet the needs of the natural environment, the structure and function of the visual system are also gradually evolved in the process of adapting to the complex natural environment. Therefore, visual stimuli that can be precisely controlled and that are similar to natural environments are crucial for resolving visual cognitive brain functions.
发明内容Contents of the invention
本申请实施例提供了一种多维度信号控制系统和方法,以实现三维环境下的认知功能测试,提高认知功能测试的测试信号维度。The embodiment of the present application provides a multi-dimensional signal control system and method to realize the cognitive function test in the three-dimensional environment and improve the test signal dimension of the cognitive function test.
第一方面,本申请实施例提供了一种多维度信号控制系统,包括:多维度 信号控制设备、三维视觉刺激设备、眼部运动检测设备和眼动信号处理设备,其中:In the first aspect, the embodiment of the present application provides a multi-dimensional signal control system, including: a multi-dimensional signal control device, a three-dimensional visual stimulation device, an eye movement detection device and an eye movement signal processing device, wherein:
三维视觉刺激设备,设置为基于预先加载的三维视觉刺激感知任务生成三维视觉刺激信号,并将三维视觉刺激信号向受检方的眼部进行展示,以使受检方的眼部随展示的三维视觉刺激信号运动;The three-dimensional visual stimulation device is configured to generate a three-dimensional visual stimulation signal based on a preloaded three-dimensional visual stimulation perception task, and display the three-dimensional visual stimulation signal to the eyes of the examinee, so that the eyes of the examinee follow the displayed three-dimensional Visual stimuli signal movement;
眼部运动检测设备,设置为检测受检方的眼部检测信息,并将眼部检测信息发送至多维度信号控制设备;The eye movement detection device is configured to detect the eye detection information of the inspected party, and send the eye detection information to the multi-dimensional signal control device;
多维度信号控制设备,设置为根据眼部检测信息生成眼部运动信息,并将眼部运动信息发送至眼动信号处理设备;The multi-dimensional signal control device is configured to generate eye movement information according to the eye detection information, and send the eye movement information to the eye movement signal processing device;
眼动信号处理设备,设置为根据眼部运动信息生成反馈信号,并将反馈信号发送至多维度信号控制设备;The eye movement signal processing device is configured to generate a feedback signal according to the eye movement information, and send the feedback signal to the multi-dimensional signal control device;
多维度信号控制设备,还设置为执行反馈信号对应的操作。The multi-dimensional signal control device is also configured to perform the operation corresponding to the feedback signal.
第二方面,本申请实施例还提供了一种多维度信号控制方法,由本申请任意实施例所提供的多维度信号控制系统执行,包括:In the second aspect, the embodiment of the present application also provides a multi-dimensional signal control method, which is executed by the multi-dimensional signal control system provided in any embodiment of the present application, including:
三维视觉刺激设备根据预先加载的三维视觉刺激感知任务生成三维视觉刺激信号,并将三维视觉刺激信号向受检方的眼部进行展示,以使受检方的眼部随展示的三维视觉刺激信号运动;The 3D visual stimulation device generates 3D visual stimulation signals according to the preloaded 3D visual stimulation perception tasks, and displays the 3D visual stimulation signals to the eyes of the inspected party, so that the inspected party's eyes follow the displayed 3D visual stimulation signals. sports;
眼部运动检测设备检测受检方的眼部检测信息,并将眼部检测信息发送至多维度信号控制设备;The eye movement detection device detects the eye detection information of the inspected party, and sends the eye detection information to the multi-dimensional signal control device;
多维度信号控制设备根据眼部检测信息生成眼部运动信息,并将眼部运动信息发送至眼动信号处理设备;The multi-dimensional signal control device generates eye movement information according to the eye detection information, and sends the eye movement information to the eye movement signal processing device;
眼动信号处理设备根据眼部运动信息生成反馈信号,并将反馈信号发送至多维度信号控制设备;The eye movement signal processing device generates a feedback signal according to the eye movement information, and sends the feedback signal to the multi-dimensional signal control device;
多维度信号控制设备执行反馈信号对应的操作。The multi-dimensional signal control device executes the operation corresponding to the feedback signal.
附图说明Description of drawings
图1是本申请实施例一所提供的一种多维度信号控制系统的结构示意图;FIG. 1 is a schematic structural diagram of a multi-dimensional signal control system provided in Embodiment 1 of the present application;
图2是本申请实施例一所提供的一种计算机设备的结构示意图;FIG. 2 is a schematic structural diagram of a computer device provided in Embodiment 1 of the present application;
图3是本申请实施例二所提供的一种多维度信号控制方法的流程图。FIG. 3 is a flow chart of a multi-dimensional signal control method provided in Embodiment 2 of the present application.
具体实施方式Detailed ways
下面结合附图和实施例对本申请作进一步的详细说明。可以理解的是,此处所描述的具体实施例仅仅用于解释本申请,而非对本申请的限定。另外还需要说明的是,为了便于描述,附图中仅示出了与本申请相关的部分而非全部结构。The application will be further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described here are only used to explain the present application, but not to limit the present application. In addition, it should be noted that, for the convenience of description, only some structures related to the present application are shown in the drawings but not all structures.
相关技术的认知任务是基于二维视觉刺激实现的,与自然环境中三维视觉环境存在一定的区别。因此,如何实现三维环境下的认知功能测试是一个亟待解决的技术问题。The cognitive tasks of related technologies are realized based on two-dimensional visual stimuli, which are somewhat different from the three-dimensional visual environment in the natural environment. Therefore, how to realize the cognitive function test in the three-dimensional environment is a technical problem to be solved urgently.
实施例一Embodiment one
图1是本申请实施例一所提供的一种多维度信号控制系统的结构示意图。本实施例提供的多维度信号控制系统可适用于灵长类动物基于多维度控制信号进行控制时的情形。如图1所示,多维度信号控制系统包括多维度信号控制设备10、三维视觉刺激设备20、眼部运动检测设备30和眼动信号处理设备40,其中:FIG. 1 is a schematic structural diagram of a multi-dimensional signal control system provided in Embodiment 1 of the present application. The multi-dimensional signal control system provided in this embodiment is applicable to situations where primates are controlled based on multi-dimensional control signals. As shown in Figure 1, the multi-dimensional signal control system includes a multi-dimensional signal control device 10, a three-dimensional visual stimulation device 20, an eye movement detection device 30 and an eye movement signal processing device 40, wherein:
三维视觉刺激设备20,设置为基于预先加载的三维视觉刺激感知任务生成三维视觉刺激信号,并将三维视觉刺激信号向受检方的眼部进行展示,以使受检方的眼部随展示的三维视觉刺激信号运动;The three-dimensional visual stimulation device 20 is configured to generate a three-dimensional visual stimulation signal based on a preloaded three-dimensional visual stimulation perception task, and present the three-dimensional visual stimulation signal to the subject's eyes, so that the subject's eyes follow the displayed Three-dimensional visual stimuli signal movement;
眼部运动检测设备30,设置为检测受检方的眼部检测信息,并将眼部检测 信息发送至多维度信号控制设备10;The eye movement detection device 30 is configured to detect the eye detection information of the inspected party, and send the eye detection information to the multi-dimensional signal control device 10;
多维度信号控制设备10,设置为根据眼部检测信息生成眼部运动信息,并将眼部运动信息发送至眼动信号处理设备40;The multi-dimensional signal control device 10 is configured to generate eye movement information according to the eye detection information, and send the eye movement information to the eye movement signal processing device 40;
眼动信号处理设备40,设置为根据眼部运动信息生成反馈信号,并将反馈信号发送至多维度信号控制设备10;The eye movement signal processing device 40 is configured to generate a feedback signal according to the eye movement information, and send the feedback signal to the multi-dimensional signal control device 10;
多维度信号控制设备10,还设置为执行反馈信号对应的操作。The multi-dimensional signal control device 10 is further configured to perform an operation corresponding to the feedback signal.
在一实施例中,三维视觉刺激设备、眼部运动检测设备和眼动信号处理设备均分别与多维度信号控制设备通信连接。In one embodiment, the three-dimensional visual stimulation device, the eye movement detection device, and the eye movement signal processing device are all communicatively connected to the multi-dimensional signal control device.
在本实施例中,多维度信号控制设备为多维度信号控制系统的核心,统筹处理与三维视觉刺激设备、眼部运动检测设备的交互,实现三维视觉刺激设备、眼部运动检测设备的输入与输出控制,可以完成眼动信号传输、奖励信号传输、以及事件编码信号的传输等操作。In this embodiment, the multi-dimensional signal control device is the core of the multi-dimensional signal control system, and coordinates the interaction with the 3D visual stimulation device and the eye movement detection device to realize the input and interaction of the 3D visual stimulation device and the eye movement detection device. The output control can complete operations such as eye movement signal transmission, reward signal transmission, and event coding signal transmission.
在一个实施例中,预先在开发工具内开发三维视觉刺激感觉任务,将开发好的三维视觉刺激感知任务导入三维视觉刺激设备,三维视觉刺激设备存储三维视觉刺激感知任务,即可执行三维视觉刺激感知任务。三维视觉刺激设备包括两部分:控制系统和显示设备。其中,控制系统用于存储、切换、传输三维视觉刺激感知任务等操作,显示设备可以为头戴3D显示屏,用于显示三维视觉刺激信号。整体来说,三维视觉刺激设备基于预先加载的三维视觉刺激感知任务生成三维视觉刺激信号进行展示,受检方的眼部随展示的三维视觉刺激信号运动,眼部运动检测设备检测受检方的眼部运动,得到眼部检测信息,并将眼部检测信息发送至多维度信号控制设备,多维度信号控制设备根据眼部检测信息生成眼部运动信息,并将眼部运动信息发送至眼动信号处理设备,眼动信号处理设备根据眼部运动信息生成反馈信号,并将反馈信号发送至多维度信号控制设备,以使多维度信号控制设备执行反馈信号对应的操作,完成三维视觉认知任务。其中,反馈信号可以为任务执行信息,如任务执行完成或任务执行未 完成,还可以为任务执行完成后的奖励信号。三维视觉刺激设备中的显示设备可以采用相关技术的虚拟现实(Virtual Reality,VR)和/或增强现实(Augmented Reality,AR)设备。In one embodiment, the three-dimensional visual stimulation sensory task is developed in the development tool in advance, and the developed three-dimensional visual stimulation perception task is imported into the three-dimensional visual stimulation device, and the three-dimensional visual stimulation device stores the three-dimensional visual stimulation perception task, and the three-dimensional visual stimulation can be performed. perception task. The three-dimensional visual stimulation equipment consists of two parts: a control system and a display device. Among them, the control system is used for operations such as storing, switching, and transmitting three-dimensional visual stimulation perception tasks, and the display device can be a head-mounted 3D display screen for displaying three-dimensional visual stimulation signals. Generally speaking, the 3D visual stimulation device generates 3D visual stimulation signals based on the preloaded 3D visual stimulation perception tasks for display, the eyes of the examinee move with the displayed 3D visual stimulation signals, and the eye movement detection equipment detects the motion of the examinee. Eye movement, get eye detection information, and send the eye detection information to the multi-dimensional signal control device, the multi-dimensional signal control device generates eye movement information according to the eye detection information, and sends the eye movement information to the eye movement signal The processing device, the eye movement signal processing device generates a feedback signal according to the eye movement information, and sends the feedback signal to the multi-dimensional signal control device, so that the multi-dimensional signal control device performs the operation corresponding to the feedback signal to complete the three-dimensional visual cognition task. Among them, the feedback signal can be task execution information, such as task execution completion or task execution incomplete, and it can also be a reward signal after task execution is completed. The display device in the three-dimensional visual stimulation device may adopt a related technology virtual reality (Virtual Reality, VR) and/or augmented reality (Augmented Reality, AR) device.
可选的,可以预先基于Unity3D开发三维视觉刺激感知任务。Unity3D同时支持多个主流平台,极大降低开发者发布多个平台的难度;并且支持C#、JavaScript和Boo等脚本语言;同时支持主要的美术资源文件格式,能够满足无开发经验的开发者的开发需求;另外,还提供了高度优化的图形渲染,内嵌Mecanim动画系统、Shuriken粒子系统等功能。三维视觉刺激感知任务的开发逻辑是向受检方(如猕猴)呈现基于三维视觉刺激的视觉认知任务,同时采集受检方的眼睛运动信号。在上述基础上,可以在受检方顺利完成任务时,发送奖励信号,给予受检方奖励;还可以在三维视觉刺激感知任务完成过程中,对比如事件开始、事件结束、视觉刺激出现、视觉刺激类型以及奖励发送等进行数字编码,通过数字编码事件的方式对任务事件进行标记。Optionally, a 3D visual stimulus perception task can be pre-developed based on Unity3D. Unity3D supports multiple mainstream platforms at the same time, which greatly reduces the difficulty for developers to release multiple platforms; it also supports scripting languages such as C#, JavaScript, and Boo; it also supports major art resource file formats, which can meet the needs of developers with no development experience. In addition, it also provides highly optimized graphics rendering, embedded Mecanim animation system, Shuriken particle system and other functions. The development logic of the three-dimensional visual stimulation perception task is to present the subject (such as a macaque) with a visual cognition task based on three-dimensional visual stimulation, and at the same time collect the subject's eye movement signals. On the basis of the above, a reward signal can be sent to reward the inspected party when the inspected party successfully completes the task; it can also be used during the completion of the three-dimensional visual stimulus perception task, such as the beginning of the event, the end of the event, the appearance of the visual stimulus, the visual Stimulus types and reward delivery are digitally coded, and task events are marked by digitally coded events.
可选的,多维度信号控制设备可以基于嵌入式开发板开发。嵌入式开发板具有较强的计算能力,灵活的开发架构,足够数量的数字和模拟的I/O端口,串口中断,同时具备定时器和计数器等功能,满足三维视觉认知功能测试中多维度信号控制设备的功能需求。Optionally, the multi-dimensional signal control device can be developed based on an embedded development board. The embedded development board has strong computing power, flexible development architecture, a sufficient number of digital and analog I/O ports, serial port interrupts, and functions such as timers and counters at the same time, meeting the multi-dimensional requirements of 3D visual cognitive function tests. Functional requirements for signal control equipment.
可选的,眼部运动检测设备可以为眼睛运动检测仪(眼动仪)。眼动仪基于快速图像处理的方法,利用高速摄像头直接采集眼睛图像,根据眼睛图像就可以计算出眼睛的位置。基于已有算法和电子计算机的计算能力,相关技术的眼动仪对眼睛运动的采样频率可以达到1000赫兹(Hz)以上,精度<=0.5度,已逐渐成为追踪眼睛运动的主要方法。眼动仪可以采用相关技术的眼动仪。以SensoMotoric Instrumens iView X高速Primate眼动仪(SMI眼动仪)为例,SMI眼动仪是一款用于非人灵长类动物的眼球运动记录仪,具有非侵入性、操作简单、眼动追踪可靠、高时间和空间解析率等特点,易整合为动物训练系统的一部分。SMI眼动仪可对单眼或者双眼暗瞳孔进行跟踪,同时输出眼睛位置的X、Y方向 的模拟电压,以及瞳孔大小等信息。通过眼动仪采集受检方的眼动信号,而非直接通过三维头盔内置的眼动追踪仪器或有创式方法向受检方眼睛植入追踪装置,方法实施简单,且能直接有效地观察受检方的状态。Optionally, the eye movement detection device may be an eye movement detector (eye tracker). The eye tracker is based on a fast image processing method, uses a high-speed camera to directly collect eye images, and calculates the position of the eyes based on the eye images. Based on existing algorithms and the computing power of electronic computers, eye trackers in related technologies can sample eye movements at a frequency above 1000 hertz (Hz), with an accuracy of <=0.5 degrees, and have gradually become the main method for tracking eye movements. The eye tracker may use an eye tracker of related technology. Take SensoMotoric Instrumens iView X High-speed Primate Eye Tracker (SMI Eye Tracker) as an example. Reliable tracking, high temporal and spatial resolution, and easy integration as part of an animal training system. The SMI eye tracker can track the dark pupils of one or both eyes, and output the analog voltage of the X and Y directions of the eye position, and the pupil size and other information at the same time. The eye movement signal of the subject is collected by the eye tracker, instead of directly implanting a tracking device into the subject's eye through the eye tracking device built in the 3D helmet or an invasive method. The method is simple to implement and can be directly and effectively observed The status of the party under prosecution.
在进行三维视觉认知功能测试时,将眼动仪置于猕猴前方,调节其位置至可以完整追踪猕猴的瞳孔,即白色线圈包裹住暗色瞳孔。通过眼动仪的控制软件,设置采样频率、眼睛位置电压范围、单眼或者双眼输出的硬件参数。硬件参数可根据实际测试需求确定。When performing a three-dimensional visual cognitive function test, the eye tracker was placed in front of the macaque, and its position was adjusted so that it could completely track the pupil of the macaque, that is, the white coil wrapped around the dark pupil. Through the control software of the eye tracker, set the hardware parameters of sampling frequency, eye position voltage range, single eye or binocular output. Hardware parameters can be determined according to actual test requirements.
在上述方案的基础上,眼部检测信息为模拟电压信息,根据眼部检测信息生成眼部运动信息,包括:对模拟电压信息进行模数转换,得到眼部运动信息。假设多维度信号控制设备基于STM32开发板开发,且眼部运动检测设备为眼动仪,在进行测试时,从眼动仪端口引出两路模拟电压输出导线,该两路信号为眼睛运动位置的X和Y坐标,范围一般可以设置为-5V~+5V。但对于STM32开发板的模数转换器(Analog-to-Digital Converter,ADC)转换范围:0V~3.6V而言,并不符合眼动仪两路输出电压的ADC要求。因此,需要采用真双极模拟电压范围±5V、±10V的ADC模块。相关技术高度符合需求的ADC模块有AD7606多通道AD数据采集模块(AD7606模块)等。眼部检测信息通过眼动仪进行信号采集,输出两路模拟电压信号,对该模拟电压信号进行模数转换后得到眼部运动信息,才能输入到三维视觉刺激设备。可选的,模拟电压信号形式的眼部检测信息先经过AD7606模块,将-5V~+5V范围模拟电压,以16位精度进行模数转换。然后,STM32开发板定时器中断对AD7606模块进行数据采样,并将该数据进行打包得到眼部运动信息,通过USB串口通信方式将数据输出至三维视觉刺激设备。On the basis of the above solution, the eye detection information is analog voltage information, and the eye movement information is generated according to the eye detection information, including: performing analog-to-digital conversion on the analog voltage information to obtain eye movement information. Assume that the multi-dimensional signal control device is developed based on the STM32 development board, and the eye movement detection device is an eye tracker. During the test, two analog voltage output wires are drawn from the eye tracker port. The two signals are the position of the eye movement. X and Y coordinates, the range can generally be set to -5V ~ +5V. However, for the conversion range of the Analog-to-Digital Converter (ADC) of the STM32 development board: 0V to 3.6V, it does not meet the ADC requirements of the two output voltages of the eye tracker. Therefore, an ADC module with a true bipolar analog voltage range of ±5V, ±10V is required. Related technologies ADC modules that highly meet the requirements include the AD7606 multi-channel AD data acquisition module (AD7606 module) and the like. The eye detection information is collected through the eye tracker, and two analog voltage signals are output. The analog voltage signals are converted to analog to digital to obtain eye movement information, which can then be input to the 3D visual stimulation device. Optionally, the eye detection information in the form of an analog voltage signal first passes through the AD7606 module, and converts the analog voltage in the range of -5V to +5V with 16-bit precision for analog-to-digital conversion. Then, the STM32 development board timer interrupts the data sampling of the AD7606 module, packs the data to obtain eye movement information, and outputs the data to the 3D visual stimulation device through the USB serial port communication.
本申请实施例提供的多维度信号控制系统包括:多维度信号控制设备、三维视觉刺激设备、眼部运动检测设备和眼动信号处理设备,其中:三维视觉刺激设备,设置为基于预先加载的三维视觉刺激感知任务生成三维视觉刺激信号,并将三维视觉刺激信号向受检方的眼部进行展示,以使受检方的眼部随展示的三维视觉刺激信号运动;眼部运动检测设备,设置为检测受检方的眼部检测信 息,并将眼部检测信息发送至多维度信号控制设备;多维度信号控制设备,设置为根据眼部检测信息生成眼部运动信息,并将眼部运动信息发送至眼动信号处理设备;眼动信号处理设备,还设置为根据眼部运动信息生成反馈信号,并将反馈信号发送至多维度信号控制设备;多维度信号控制设备,还设置为执行反馈信号对应的操作。通过预先在三维视觉刺激设备中加载开发好的三维视觉刺激感知任务实现三维环境下的刺激,通过多维度信号控制设备实现三维视觉刺激设备与眼部运动检测设备的信息交互,实现了三维环境下的认知功能测试,提高了认知功能测试的测试信号维度。The multi-dimensional signal control system provided by the embodiment of the present application includes: multi-dimensional signal control equipment, three-dimensional visual stimulation equipment, eye movement detection equipment and eye movement signal processing equipment, wherein: the three-dimensional visual stimulation equipment is set based on preloaded three-dimensional The visual stimulation perception task generates a three-dimensional visual stimulation signal, and displays the three-dimensional visual stimulation signal to the eyes of the inspected party, so that the inspected party's eyes move with the displayed three-dimensional visual stimulation signal; the eye movement detection device is set In order to detect the eye detection information of the inspected party, and send the eye detection information to the multi-dimensional signal control device; the multi-dimensional signal control device is set to generate eye movement information according to the eye detection information, and send the eye movement information to to the eye movement signal processing device; the eye movement signal processing device is also set to generate a feedback signal according to the eye movement information, and sends the feedback signal to the multi-dimensional signal control device; the multi-dimensional signal control device is also set to execute the feedback signal corresponding operate. Realize stimulation in a three-dimensional environment by pre-loading the developed three-dimensional visual stimulation perception task in the three-dimensional visual stimulation device, and realize the information interaction between the three-dimensional visual stimulation device and the eye movement detection device through the multi-dimensional signal control device, and realize the three-dimensional environment. The cognitive function test improves the test signal dimension of the cognitive function test.
在本申请的一种实施方式中,根据眼部运动信息生成反馈信号,包括:根据眼部运动信息判断三维视觉刺激感知任务是否完成;当三维视觉刺激感知任务完成时,生成奖励信号作为反馈信号。可选的,三维视觉刺激设备生成的反馈信号可以为奖励信号,在受检方完成三维视觉刺激感知任务时进行奖励,正向促进了三维视觉刺激感知任务的完成。示例性的,三维视觉刺激信号可以为红色球体,可以将展示的红色球体和采集的眼部检测信息进行比对,判断受检方是否盯住红色球体,并在受检方盯住红色球体时判定三维视觉刺激感知任务完成,若受检方未盯住红色球体,则判定三维视觉刺激感知任务未完成。In one embodiment of the present application, generating the feedback signal according to the eye movement information includes: judging whether the three-dimensional visual stimulation perception task is completed according to the eye movement information; when the three-dimensional visual stimulation perception task is completed, generating a reward signal as the feedback signal . Optionally, the feedback signal generated by the 3D visual stimulation device may be a reward signal, which rewards the inspected party when completing the 3D visual stimulation perception task, and positively promotes the completion of the 3D visual stimulation perception task. Exemplarily, the three-dimensional visual stimulation signal can be a red sphere, and the displayed red sphere can be compared with the collected eye detection information to determine whether the subject is staring at the red sphere, and when the subject is staring at the red sphere, It is judged that the three-dimensional visual stimulation perception task is completed, if the subject does not stare at the red sphere, it is judged that the three-dimensional visual stimulation perception task is not completed.
在上述方案的基础上,系统还包括奖励装置;多维度信号控制设备,还设置为根据奖励信号生成设定电平信号输出至奖励装置;奖励装置,设置为在接收到设定电平信号时执行奖励操作。可选的,系统中设置奖励装置完成对受检方的奖励操作。以受检方为猕猴为例,为了给猕猴示意任务完成正确或者安抚猕猴情绪时,会给予葡萄果汁、苹果果汁等饮料奖励。多维度信号控制设备接收到三维视觉刺激设备发送的奖励信号后,生成设定电平信号输出至奖励装置,以使奖励装置执行奖励操作。可选的,设定电平信号可以根据实际需求设置,如可以将高电平信号设置为奖励电平信号,将低电平信号设置为停止奖励电平信号;还可以将低电平信号设置为奖励电平信号,将高电平信号设置为停止奖励电平信号。On the basis of the above scheme, the system also includes a reward device; the multi-dimensional signal control device is also set to generate a set level signal according to the reward signal and output it to the reward device; the reward device is set to receive the set level signal Perform reward actions. Optionally, a reward device is set in the system to complete the reward operation for the inspected party. Taking macaques as the subject of the prosecution as an example, in order to show the macaques that the task is completed correctly or to appease the macaques, they will give grape juice, apple juice and other drinks as rewards. After receiving the reward signal sent by the three-dimensional visual stimulation device, the multi-dimensional signal control device generates a signal with a set level and outputs it to the reward device, so that the reward device performs a reward operation. Optionally, the set level signal can be set according to actual needs, such as the high level signal can be set as the reward level signal, the low level signal can be set as the stop reward level signal; the low level signal can also be set For reward level signal, set high level signal to stop reward level signal.
在一个实施例中,根据奖励信号生成设定电平信号输出至奖励装置,包括:根据奖励信号确定奖励持续时间,将奖励持续时间作为计数周期;启动计时,输出奖励电平信号,在奖励电压输出时间到达奖励持续时间时输出停止奖励电平信号。示例性的,可以基于定时器实现设定电平信号的输出。首先,根据奖励信号中的设定位数值,确定奖励持续时间,将奖励持续时间作为定时器的计数周期,调用定时器初始化,基于定时器的计数周期配置定时器。在多维度认知功能测试执行时,开启定时器功能,启动定时器开始计数;定时器启动计数后,通过设定输出口输出奖励电平信号,并在通过定时器中断函数响应定时器计数结束时,关闭定时器,清除中断标志,定时器中断函数内通过设定输出口输出停止奖励电平信号,完成奖励程序。In one embodiment, generating a set level signal according to the reward signal and outputting it to the reward device includes: determining the reward duration according to the reward signal, using the reward duration as the counting period; starting timing, outputting the reward level signal, and When the output time reaches the reward duration, the stop reward level signal is output. Exemplarily, the output of the set level signal can be implemented based on a timer. First, determine the duration of the reward according to the set bit value in the reward signal, use the duration of the reward as the counting period of the timer, call the timer initialization, and configure the timer based on the counting period of the timer. When the multi-dimensional cognitive function test is executed, the timer function is turned on, and the timer starts counting; after the timer starts counting, the reward level signal is output by setting the output port, and the timer counting ends in response to the timer interrupt function , the timer is closed, the interrupt flag is cleared, and the timer interrupt function outputs the stop reward level signal by setting the output port to complete the reward program.
可选的,奖励装置包括液体存放装置、电磁阀泵和液体导管,液体导管一端连接至液体存放装置,根据接收到的电平信号执行奖励操作,包括:在接收到奖励电平信号时,电磁阀泵开启,液体存放装置中的液体通过液体导管流出;在接收到停止奖励电平信号时,电磁阀泵关闭,液体存放装置中的液体停止流出。示例性的,奖励装置可以为方形盒子,内部集成一个电磁阀泵,盒子上方设置一条液体导管,盒子下方为电源线、导通控制线以及地线。液体导管的一端插入装有果汁的量瓶(即液体存放装置),另外一端连接一个小喷头放入受检方嘴部内。当对导通控制线施加设定奖励电压时,则开启电磁阀,果汁顺着导管流出,此时受检方获得奖励。当对导通控制线施加设定停止奖励电压时,则关闭电磁阀,果汁停止流出,此时受检方不获得奖励。Optionally, the incentive device includes a liquid storage device, a solenoid valve pump and a liquid conduit, one end of the liquid conduit is connected to the liquid storage device, and the reward operation is performed according to the received level signal, including: when receiving the reward level signal, the electromagnetic The valve pump is turned on, and the liquid in the liquid storage device flows out through the liquid conduit; when receiving the stop reward level signal, the electromagnetic valve pump is closed, and the liquid in the liquid storage device stops flowing out. Exemplarily, the reward device may be a square box with a solenoid valve pump integrated inside, a liquid conduit arranged above the box, and a power line, conduction control line, and ground line below the box. One end of the liquid conduit is inserted into a measuring bottle (i.e., a liquid storage device) containing fruit juice, and the other end is connected to a small nozzle and put into the mouth of the inspected party. When the set reward voltage is applied to the conduction control line, the electromagnetic valve is opened, and the juice flows out along the conduit, and the inspected party is rewarded at this time. When the set stop reward voltage is applied to the conduction control line, the electromagnetic valve is closed, and the juice stops flowing out. At this time, the inspected party does not get a reward.
在上述方案的基础上,系统还包括电生理信号采集设备;三维视觉刺激设备,还设置为在检测到预先设置的电生理事件时,生成电生理事件触发信号发送至多维度信号控制设备;多维度信号控制设备,还设置为对电生理事件触发信号进行处理,得到电生理事件标记信号,并将电生理事件标记信号发送至电生理信号采集设备;电生理信号采集设备,设置为对电生理事件标记信号进行处理,得到检测分析结果。可选的,预先设置的电生理事件包括视觉刺激出现、 视觉刺激消失、视觉刺激呈现位置变化和视觉刺激呈现深度变化中的至少一个。On the basis of the above scheme, the system also includes an electrophysiological signal acquisition device; a three-dimensional visual stimulation device, which is also configured to generate an electrophysiological event trigger signal and send it to the multi-dimensional signal control device when a preset electrophysiological event is detected; the multi-dimensional The signal control device is also configured to process the electrophysiological event trigger signal to obtain the electrophysiological event marker signal, and send the electrophysiological event marker signal to the electrophysiological signal acquisition device; the electrophysiological signal acquisition device is configured to monitor the electrophysiological event The labeled signal is processed to obtain the detection and analysis results. Optionally, the preset electrophysiological event includes at least one of appearance of visual stimulus, disappearance of visual stimulus, change of presentation position of visual stimulus, and change of presentation depth of visual stimulus.
可选的,预先设置的电生理事件还可以包括视觉刺激设定位置事件和视觉刺激设定深度事件。Optionally, the preset electrophysiological events may also include a visual stimulus set position event and a visual stimulus set depth event.
为了实现测试过程的记录及测试的统计分析,添加电生理信号采集设备采集测试过程中的电生理事件信号。以多维度信号控制设备基于STM32开发板开发为例,电生理事件标记原理为:在检测到电生理事件时,初始化Strobe位为高电平信号,并向16个数字信号输入位传递电生理事件,然后再给Strobe一个低电平,随后迅速给一个高电平。多维度信号控制设备以设定频率对接收端口进行刷新,读取一次值。这样就顺利完成了一次电生理事件的编码传送,可在多维度信号控制设备的控制主机界面看到电生理事件的标记信号。In order to realize the recording of the test process and the statistical analysis of the test, an electrophysiological signal acquisition device is added to collect the electrophysiological event signals during the test. Taking the development of multi-dimensional signal control equipment based on the STM32 development board as an example, the principle of electrophysiological event marking is: when an electrophysiological event is detected, the Strobe bit is initialized as a high-level signal, and the electrophysiological event is transmitted to 16 digital signal input bits , and then give Strobe a low level, and then quickly give a high level. The multi-dimensional signal control device refreshes the receiving port at a set frequency and reads the value once. In this way, the encoded transmission of an electrophysiological event is successfully completed, and the marker signal of the electrophysiological event can be seen on the control host interface of the multi-dimensional signal control device.
在一个实施例中,电生理事件触发信号为电生理事件编码,对电生理事件触发信号进行处理,得到电生理事件标记信号,包括:将电生理事件编码的编码值转换为二进制数值,得到电生理事件标记信号。In one embodiment, the electrophysiological event trigger signal is an electrophysiological event code, and processing the electrophysiological event trigger signal to obtain an electrophysiological event marker signal includes: converting the encoded value of the electrophysiological event code into a binary value to obtain an electrophysiological event Physiological event marker signals.
为实现电生理事件的快速传输,可以将电生理事件触发信号设置为编码的形式。示例性的,发送的电生理事件信号为打包数据,是一串字节长度不等长的数组。数组中每个位置的数据均设置其对应的含义。在接收到电生理事件编码后,将电生理事件编码的编码值转换为二进制数值,得到电生理事件标记信号,依次赋给每个输出口输出。始终保持输出,直到下一次输出刷新。In order to realize the rapid transmission of electrophysiological events, the electrophysiological event trigger signals can be set in the form of encoding. Exemplarily, the transmitted electrophysiological event signal is packaged data, which is a series of arrays with different byte lengths. The data at each position in the array sets its corresponding meaning. After receiving the electrophysiological event code, the coded value of the electrophysiological event code is converted into a binary value to obtain an electrophysiological event marker signal, which is sequentially assigned to each output port for output. Always keep the output until the next output flush.
需要说明的是,本实施例中的三维视觉刺激设备、眼部运动检测设备、眼动信号处理设备、多维度信号控制设备、电生理信号采集设备和奖励装置等均可以以通用计算机设备的形式表现。It should be noted that in this embodiment, the three-dimensional visual stimulation equipment, eye movement detection equipment, eye movement signal processing equipment, multi-dimensional signal control equipment, electrophysiological signal acquisition equipment and rewarding devices can all be in the form of general computer equipment Performance.
如图2所示,图2示出了适于用来实现本申请实施例的示例性计算机设备212的结构示意图,本申请提供的计算机设备212可以包括:一个或者多个处理器或者处理单元216,系统存储器228,连接不同系统组件(包括系统存储器228和处理单元216)的总线218。As shown in FIG. 2, FIG. 2 shows a schematic structural diagram of an exemplary computer device 212 suitable for implementing the embodiments of the present application. The computer device 212 provided by the present application may include: one or more processors or processing units 216 , the system memory 228, the bus 218 connecting different system components (including the system memory 228 and the processing unit 216).
其中,总线218表示几类总线结构中的一种或多种,包括存储器总线或者存储器控制器,外围总线,图形加速端口,处理器或者使用多种总线结构中的任意总线结构的局域总线。举例来说,这些体系结构可以包括工业标准体系结构(Industrial Standard Architecture,ISA)总线,微通道体系结构总线,增强型ISA总线、视频电子标准协会局域总线以及外围组件互连总线。Wherein, the bus 218 represents one or more of several types of bus structures, including a memory bus or memory controller, a peripheral bus, a graphics acceleration port, a processor, or a local bus using any bus structure in various bus structures. These architectures may include, for example, an Industrial Standard Architecture (ISA) bus, a Micro Channel Architecture bus, an Enhanced ISA bus, a Video Electronics Standards Association local bus, and a Peripheral Component Interconnect bus.
计算机设备212可以包括多种计算机系统可读介质。这些介质可以是任何能够被计算机设备212访问的可用介质,包括易失性和非易失性介质,可移动的和不可移动的介质。 Computer device 212 may include a variety of computer system readable media. These media can be any available media that can be accessed by computing device 212 and include both volatile and nonvolatile media, removable and non-removable media.
系统存储器228可以包括易失性存储器形式的计算机系统可读介质,例如随机存取存储器(Random Access Memory,RAM)230和/或高速缓存存储器232。计算机设备212可以进一步包括其它可移动/不可移动的、易失性/非易失性计算机系统存储介质。仅作为举例,存储系统234可以用于读写不可移动的、非易失性磁介质(通常称为“硬盘驱动器”)。系统存储器228还可以提供用于对可移动非易失性磁盘(例如“软盘”)读写的磁盘驱动器,以及对可移动非易失性光盘(例如CD-ROM,DVD-ROM或者其它光介质)读写的光盘驱动器。在这些情况下,每个驱动器可以通过一个或者多个数据介质接口与总线218相连。系统存储器228可以包括至少一个程序产品,该程序产品具有一组(例如至少一个)程序模块,这些程序模块被配置以执行本申请实施例的功能。 System memory 228 may include computer system readable media in the form of volatile memory, such as Random Access Memory (RAM) 230 and/or cache memory 232 . Computer device 212 may further include other removable/non-removable, volatile/nonvolatile computer system storage media. By way of example only, storage system 234 may be used to read from and write to non-removable, non-volatile magnetic media (commonly referred to as a "hard drive"). System memory 228 may also provide disk drives for reading and writing to removable non-volatile disks (such as "floppy disks"), and for removable non-volatile optical disks (such as CD-ROM, DVD-ROM, or other optical media). ) read and write CD-ROM drive. In these cases, each drive may be connected to bus 218 through one or more data media interfaces. The system memory 228 may include at least one program product having a set (eg, at least one) of program modules configured to perform the functions of the embodiments of the present application.
具有一组(至少一个)程序模块242的程序/实用工具240,可以存储在例如系统存储器228中,这样的程序模块242包括操作系统、一个或者多个应用程序、其它程序模块以及程序数据,这些示例中的每一个或某种组合中可能包括网络环境的实现。程序模块242通常执行本申请所描述的实施例中的功能和/或方法。Programs/utilities 240 may be stored, for example, in system memory 228 as a set (at least one) of program modules 242, such program modules 242 including an operating system, one or more application programs, other program modules, and program data, which Each or some combination of the examples may include the implementation of a network environment. The program module 242 generally executes the functions and/or methods in the embodiments described in this application.
计算机设备212也可以与一个或多个外部设备214(例如键盘、指向设备、显示器224等)通信,还可与一个或者多个使得用户能与该计算机设备212交互的设备通信,和/或与使得该计算机设备212能与一个或多个其它计算设备进行通 信的任何设备(例如网卡,调制解调器等)通信。这种通信可以通过输入/输出(I/O)接口222进行。并且,计算机设备212还可以通过网络适配器220与一个或者多个网络(例如局域网,广域网和/或公共网络,例如因特网)通信。如图2所示,网络适配器220通过总线218与计算机设备212的其它模块通信。应当明白,还可以结合计算机设备212使用其它硬件和/或软件模块,包括:微代码、设备驱动器、冗余处理单元、外部磁盘驱动阵列、磁盘阵列系统、磁带驱动器以及数据备份存储系统等。The computer device 212 may also communicate with one or more external devices 214 (e.g., a keyboard, pointing device, display 224, etc.), and with one or more devices that enable a user to interact with the computer device 212, and/or with Any device (eg, network card, modem, etc.) that enables the computing device 212 to communicate with one or more other computing devices. Such communication may occur through input/output (I/O) interface 222 . Also, the computer device 212 can also communicate with one or more networks (eg, a local area network, a wide area network, and/or a public network, such as the Internet) through the network adapter 220 . As shown in FIG. 2 , network adapter 220 communicates with other modules of computer device 212 via bus 218 . It should be appreciated that other hardware and/or software modules may also be used in conjunction with computer device 212, including: microcode, device drivers, redundant processing units, external disk drive arrays, disk array systems, tape drives, and data backup storage systems, among others.
处理单元216可以通过运行存储在系统存储器228中的多个程序中其他程序的至少一个,从而执行各种功能应用以及数据处理。The processing unit 216 can execute various functional applications and data processing by running at least one of other programs among a plurality of programs stored in the system memory 228 .
在一实施例中,三维视觉刺激设备、眼部运动检测设备、眼动信号处理设备、多维度信号控制设备、电生理信号采集设备和奖励装置中的任一,可以包括如上所述的通用计算机设备。In one embodiment, any of the three-dimensional visual stimulation equipment, eye movement detection equipment, eye movement signal processing equipment, multi-dimensional signal control equipment, electrophysiological signal acquisition equipment and rewarding device may include the general-purpose computer as described above equipment.
实施例二Embodiment two
图3是本申请实施例二所提供的一种多维度信号控制方法的流程图。本实施例可适用于对灵长类动物基于多维度控制信号进行控制时的情形。该方法由本申请任意实施例所提供的多维度信号控制系统执行。本实施例中,与上述各实施例相同或相应的术语的解释在此不再赘述。FIG. 3 is a flow chart of a multi-dimensional signal control method provided in Embodiment 2 of the present application. This embodiment is applicable to the situation of controlling primates based on multi-dimensional control signals. The method is executed by the multi-dimensional signal control system provided in any embodiment of the present application. In this embodiment, explanations of terms that are the same as or corresponding to those in the foregoing embodiments are not repeated here.
如图3所示,该方法包括:As shown in Figure 3, the method includes:
S310、三维视觉刺激设备根据预先加载的三维视觉刺激感知任务生成三维视觉刺激信号,并将三维视觉刺激信号向受检方的眼部进行展示,以使受检方的眼部随展示的三维视觉刺激信号运动。S310. The three-dimensional visual stimulation device generates three-dimensional visual stimulation signals according to the preloaded three-dimensional visual stimulation perception tasks, and displays the three-dimensional visual stimulation signals to the eyes of the examinee, so that the eyes of the examinee follow the displayed three-dimensional vision. Stimulate signal movement.
S320、眼部运动检测设备检测受检方的眼部检测信息,并将眼部检测信息发送至多维度信号控制设备。S320. The eye movement detection device detects the eye detection information of the inspected party, and sends the eye detection information to the multi-dimensional signal control device.
S330、多维度信号控制设备根据眼部检测信息生成眼部运动信息,并将眼部运动信息发送至眼动信号处理设备。S330. The multi-dimensional signal control device generates eye movement information according to the eye detection information, and sends the eye movement information to the eye movement signal processing device.
S340、眼动信号处理设备根据眼部运动信息生成反馈信号,并将反馈信号发送至多维度信号控制设备。S340. The eye movement signal processing device generates a feedback signal according to the eye movement information, and sends the feedback signal to the multi-dimensional signal control device.
S350、多维度信号控制设备执行反馈信号对应的操作。S350. The multi-dimensional signal control device executes an operation corresponding to the feedback signal.
本申请实施例通过三维视觉刺激设备根据预先加载的三维视觉刺激感知任务生成三维视觉刺激信号,并将三维视觉刺激信号向受检方的眼部进行展示,以使受检方的眼部随展示的三维视觉刺激信号运动;眼部运动检测设备检测受检方的眼部检测信息,并将眼部检测信息发送至多维度信号控制设备;多维度信号控制设备根据眼部检测信息生成眼部运动信息,并将眼部运动信息发送至眼动信号处理设备;眼动信号处理设备根据眼部运动信息生成反馈信号,并将反馈信号发送至多维度信号控制设备;多维度信号控制设备执行反馈信号对应的操作,通过多维度信号控制设备实现三维视觉刺激设备与眼部运动检测设备的信息交互,实现了三维环境下的认知功能测试,提高了认知功能测试的测试信号维度。In the embodiment of the present application, a 3D visual stimulation device is used to generate a 3D visual stimulation signal according to a preloaded 3D visual stimulation perception task, and the 3D visual stimulation signal is displayed to the examinee's eyes, so that the examinee's eyes follow the display. The three-dimensional visual stimulation signal movement; the eye movement detection device detects the eye detection information of the inspected party, and sends the eye detection information to the multi-dimensional signal control device; the multi-dimensional signal control device generates eye movement information according to the eye detection information , and send the eye movement information to the eye movement signal processing device; the eye movement signal processing device generates a feedback signal according to the eye movement information, and sends the feedback signal to the multi-dimensional signal control device; the multi-dimensional signal control device executes the feedback signal corresponding to Operation, through the multi-dimensional signal control equipment to realize the information interaction between the three-dimensional visual stimulation equipment and the eye movement detection equipment, realize the cognitive function test in the three-dimensional environment, and improve the test signal dimension of the cognitive function test.
可选的,在上述方案的基础上,根据眼部运动信息生成反馈信号,包括:根据眼部运动信息判断三维视觉刺激感知任务是否完成;当三维视觉刺激感知任务完成时,生成奖励信号作为反馈信号。Optionally, on the basis of the above scheme, generating a feedback signal according to eye movement information includes: judging whether the three-dimensional visual stimulation perception task is completed according to the eye movement information; when the three-dimensional visual stimulation perception task is completed, generating a reward signal as feedback Signal.
可选的,在上述方案的基础上,系统还包括奖励装置,方法还包括:Optionally, on the basis of the above scheme, the system also includes a reward device, and the method also includes:
多维度信号控制设备根据奖励信号生成设定电平信号输出至奖励装置;The multi-dimensional signal control device generates a set level signal according to the reward signal and outputs it to the reward device;
奖励装置在接收到设定电平信号时执行奖励操作。The reward means performs a reward operation upon receiving the set level signal.
可选的,在上述方案的基础上,根据奖励信号生成设定电平信号输出至奖励装置,包括:Optionally, on the basis of the above scheme, a set level signal is generated according to the reward signal and output to the reward device, including:
根据奖励信号确定奖励持续时间,将奖励持续时间作为计数周期;Determine the reward duration according to the reward signal, and use the reward duration as the counting period;
启动计时,输出奖励电平信号,在奖励电压输出时间到达奖励持续时间时输出停止奖励电平信号。Start the timing, output the reward level signal, and output the stop reward level signal when the reward voltage output time reaches the reward duration.
可选的,在上述方案的基础上,奖励装置包括液体存放装置、电磁阀泵和液体导管,液体导管一端连接至液体存放装置,根据接收到的电平信号执行奖励操作,包括:Optionally, on the basis of the above solution, the incentive device includes a liquid storage device, a solenoid valve pump, and a liquid conduit. One end of the liquid conduit is connected to the liquid storage device, and the reward operation is performed according to the received level signal, including:
在接收到奖励电平信号时,电磁阀泵开启,液体存放装置中的液体通过液体导管流出;When the reward level signal is received, the solenoid valve pump is turned on, and the liquid in the liquid storage device flows out through the liquid conduit;
在接收到停止奖励电平信号时,电磁阀泵关闭,液体存放装置中的液体停止流出。When receiving the stop incentive level signal, the solenoid valve pump is turned off, and the liquid in the liquid storage device stops flowing out.
可选的,在上述方案的基础上,眼部检测信息为模拟电压信息,根据眼部检测信息生成眼部运动信息,包括:Optionally, on the basis of the above solution, the eye detection information is analog voltage information, and the eye movement information is generated according to the eye detection information, including:
对模拟电压信息进行模数转换,得到眼部运动信息。Perform analog-to-digital conversion on the analog voltage information to obtain eye movement information.
可选的,在上述方案的基础上,系统还包括电生理信号采集设备,方法还包括:Optionally, on the basis of the above solution, the system also includes an electrophysiological signal acquisition device, and the method also includes:
三维视觉刺激设备在检测到预先设置的电生理事件时,生成电生理事件触发信号发送至多维度信号控制设备;When the three-dimensional visual stimulation device detects a preset electrophysiological event, it generates an electrophysiological event trigger signal and sends it to the multi-dimensional signal control device;
多维度信号控制设备对电生理事件触发信号进行处理,得到电生理事件标记信号,并将电生理事件标记信号发送至电生理信号采集设备;The multi-dimensional signal control device processes the electrophysiological event trigger signal to obtain the electrophysiological event marker signal, and sends the electrophysiological event marker signal to the electrophysiological signal acquisition device;
电生理信号采集设备对电生理事件标记信号进行处理,得到检测分析结果。The electrophysiological signal acquisition device processes the electrophysiological event marker signal to obtain detection and analysis results.
可选的,在上述方案的基础上,电生理事件触发信号为电生理事件编码,对电生理事件触发信号进行处理,得到电生理事件标记信号,包括:Optionally, on the basis of the above scheme, the electrophysiological event trigger signal is an electrophysiological event code, and the electrophysiological event trigger signal is processed to obtain an electrophysiological event marker signal, including:
将电生理事件编码的编码值转换为二进制数值,得到电生理事件标记信号。The encoded value of the electrophysiological event code is converted into a binary value to obtain an electrophysiological event marker signal.
可选的,在上述方案的基础上,预先设置的电生理事件包括视觉刺激出现、视觉刺激消失、视觉刺激呈现位置变化和视觉刺激呈现深度变化中的至少一个。Optionally, based on the above solution, the preset electrophysiological events include at least one of appearance of visual stimulus, disappearance of visual stimulus, change of presentation position of visual stimulus, and change of presentation depth of visual stimulus.

Claims (10)

  1. 一种多维度信号控制系统,包括:多维度信号控制设备、三维视觉刺激设备、眼部运动检测设备和眼动信号处理设备,其中:A multi-dimensional signal control system, including: multi-dimensional signal control equipment, three-dimensional visual stimulation equipment, eye movement detection equipment and eye movement signal processing equipment, wherein:
    所述三维视觉刺激设备,设置为基于预先加载的三维视觉刺激感知任务生成三维视觉刺激信号,并将所述三维视觉刺激信号向受检方的眼部进行展示,以使所述受检方的眼部随展示的所述三维视觉刺激信号运动;The 3D visual stimulation device is configured to generate a 3D visual stimulation signal based on a preloaded 3D visual stimulation perception task, and present the 3D visual stimulation signal to the eyes of the examinee, so that the examinee's Eyes move with the three-dimensional visual stimulation signal displayed;
    所述眼部运动检测设备,设置为检测所述受检方的眼部检测信息,并将所述眼部检测信息发送至所述多维度信号控制设备;The eye movement detection device is configured to detect eye detection information of the inspected party, and send the eye detection information to the multi-dimensional signal control device;
    所述多维度信号控制设备,设置为根据所述眼部检测信息生成眼部运动信息,并将所述眼部运动信息发送至所述眼动信号处理设备;The multi-dimensional signal control device is configured to generate eye movement information according to the eye detection information, and send the eye movement information to the eye movement signal processing device;
    所述眼动信号处理设备,设置为根据所述眼部运动信息生成反馈信号,并将所述反馈信号发送至所述多维度信号控制设备;The eye movement signal processing device is configured to generate a feedback signal according to the eye movement information, and send the feedback signal to the multi-dimensional signal control device;
    所述多维度信号控制设备,还设置为执行所述反馈信号对应的操作。The multi-dimensional signal control device is further configured to perform an operation corresponding to the feedback signal.
  2. 根据权利要求1所述的系统,其中,所述根据所述眼部运动信息生成反馈信号,包括:The system according to claim 1, wherein said generating a feedback signal according to said eye movement information comprises:
    根据所述眼部运动信息判断所述三维视觉刺激感知任务是否完成;judging whether the three-dimensional visual stimulus perception task is completed according to the eye movement information;
    当所述三维视觉刺激感知任务完成时,生成奖励信号作为所述反馈信号。When the three-dimensional visual stimulus perception task is completed, a reward signal is generated as the feedback signal.
  3. 根据权利要求2所述的系统,所述系统还包括奖励装置;The system of claim 2, further comprising a reward device;
    所述多维度信号控制设备,还设置为根据所述奖励信号生成设定电平信号输出至所述奖励装置;The multi-dimensional signal control device is further configured to generate a set level signal according to the reward signal and output it to the reward device;
    所述奖励装置,设置为在接收到所述设定电平信号时执行奖励操作。The rewarding device is configured to perform a rewarding operation when receiving the set level signal.
  4. 根据权利要求3所述的系统,其中,所述根据所述奖励信号生成设定电平信号输出至所述奖励装置,包括:The system according to claim 3, wherein said generating a set level signal according to said reward signal to output to said reward device comprises:
    根据所述奖励信号确定奖励持续时间,将所述奖励持续时间作为计数周期;determining a reward duration according to the reward signal, using the reward duration as a counting period;
    启动计时,输出奖励电平信号,在奖励电压输出时间到达所述奖励持续时间时输出停止奖励电平信号。Start timing, output a reward level signal, and output a stop reward level signal when the reward voltage output time reaches the reward duration.
  5. 根据权利要求4所述的系统,其中,所述奖励装置包括液体存放装置、电磁阀泵和液体导管,所述液体导管一端连接至所述液体存放装置,所述根据接收到的电平信号执行奖励操作,包括:The system according to claim 4, wherein the incentive device comprises a liquid storage device, a solenoid valve pump, and a liquid conduit, one end of the liquid conduit is connected to the liquid storage device, and the execution according to the received level signal Reward actions, including:
    在接收到所述奖励电平信号时,所述电磁阀泵开启,所述液体存放装置中的液体通过所述液体导管流出;When receiving the reward level signal, the solenoid valve pump is turned on, and the liquid in the liquid storage device flows out through the liquid conduit;
    在接收到所述停止奖励电平信号时,所述电磁阀泵关闭,所述液体存放装置中的液体停止流出。When receiving the stop incentive level signal, the solenoid valve pump is turned off, and the liquid in the liquid storage device stops flowing out.
  6. 根据权利要求1所述的系统,其中,所述眼部检测信息为模拟电压信息,所述根据所述眼部检测信息生成眼部运动信息,包括:The system according to claim 1, wherein the eye detection information is analog voltage information, and the generating eye movement information according to the eye detection information comprises:
    对所述模拟电压信息进行模数转换,得到所述眼部运动信息。performing analog-to-digital conversion on the analog voltage information to obtain the eye movement information.
  7. 根据权利要求1所述的系统,所述系统还包括电生理信号采集设备;The system according to claim 1, further comprising an electrophysiological signal acquisition device;
    所述三维视觉刺激设备,还设置为在检测到预先设置的电生理事件时,生成电生理事件触发信号发送至所述多维度信号控制设备;The three-dimensional visual stimulation device is further configured to generate an electrophysiological event trigger signal and send it to the multi-dimensional signal control device when a preset electrophysiological event is detected;
    所述多维度信号控制设备,还设置为对所述电生理事件触发信号进行处理,得到电生理事件标记信号,并将所述电生理事件标记信号发送至所述电生理信号采集设备;The multi-dimensional signal control device is further configured to process the electrophysiological event trigger signal to obtain an electrophysiological event marker signal, and send the electrophysiological event marker signal to the electrophysiological signal acquisition device;
    所述电生理信号采集设备,设置为对所述电生理事件标记信号进行处理,得到检测分析结果。The electrophysiological signal acquisition device is configured to process the electrophysiological event marker signal to obtain detection and analysis results.
  8. 根据权利要求7所述的系统,其中,所述电生理事件触发信号为电生理事件编码,所述对所述电生理事件触发信号进行处理,得到电生理事件标记信号,包括:The system according to claim 7, wherein the electrophysiological event trigger signal is an electrophysiological event code, and the processing of the electrophysiological event trigger signal to obtain an electrophysiological event marker signal includes:
    将所述电生理事件编码的编码值转换为二进制数值,得到所述电生理事件标记信号。converting the encoded value of the electrophysiological event into a binary value to obtain the electrophysiological event marker signal.
  9. 根据权利要求7所述的系统,其中,所述预先设置的电生理事件包括视觉刺激出现、视觉刺激消失、视觉刺激呈现位置变化和视觉刺激呈现深度变化中的至少一个。The system according to claim 7, wherein the preset electrophysiological event includes at least one of appearance of visual stimulus, disappearance of visual stimulus, change of visual stimulus presentation position, and change of visual stimulus presentation depth.
  10. 一种多维度信号控制方法,由权利要求1-9任一项所述的多维度信号控制系统执行,包括:A multi-dimensional signal control method, performed by the multi-dimensional signal control system according to any one of claims 1-9, comprising:
    三维视觉刺激设备根据预先加载的三维视觉刺激感知任务生成三维视觉刺激信号,并将所述三维视觉刺激信号向受检方的眼部进行展示,以使所述受检方的眼部随展示的所述三维视觉刺激信号运动;The 3D visual stimulation device generates 3D visual stimulation signals according to the preloaded 3D visual stimulation perception tasks, and displays the 3D visual stimulation signals to the eyes of the examinee, so that the eyes of the examinee follow the displayed The three-dimensional visual stimulation signal movement;
    眼部运动检测设备检测所述受检方的眼部检测信息,并将所述眼部检测信息发送至多维度信号控制设备;The eye movement detection device detects the eye detection information of the inspected party, and sends the eye detection information to the multi-dimensional signal control device;
    所述多维度信号控制设备根据所述眼部检测信息生成眼部运动信息,并将所述眼部运动信息发送至眼动信号处理设备;The multi-dimensional signal control device generates eye movement information according to the eye detection information, and sends the eye movement information to an eye movement signal processing device;
    所述眼动信号处理设备根据所述眼部运动信息生成反馈信号,并将所述反馈信号发送至多维度信号控制设备;The eye movement signal processing device generates a feedback signal according to the eye movement information, and sends the feedback signal to a multi-dimensional signal control device;
    所述多维度信号控制设备执行所述反馈信号对应的操作。The multi-dimensional signal control device executes an operation corresponding to the feedback signal.
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