WO2023119465A1

WO2023119465A1 - Information processing method, computer program, and information processing device

Info

Publication number: WO2023119465A1
Application number: PCT/JP2021/047486
Authority: WO
Inventors: 修一松田
Original assignee: 株式会社エクサウィザーズ
Priority date: 2021-12-22
Filing date: 2021-12-22
Publication date: 2023-06-29
Also published as: JP7253123B1; JPWO2023119465A1

Abstract

Provided are an information processing method, a computer program, and an information processing device that can be expected to assist selection of a pharmaceutical by a user.　An information processing method according to an embodiment comprises an information processing device: acquiring information in which a pharmaceutical prescribed for an injury/disease and a utilization period of the pharmaceutical are associated with each other; and estimating the level of the medicinal effect of the pharmaceutical on the basis of the acquired information. The information processing device may estimate that the shorter the utilization period of the pharmaceutical, the higher the medicinal effect of the pharmaceutical, in which case the pharmaceutical may be a pharmaceutical for remedying the state of the injury/disease by administration. Alternatively, the information processing device may estimate that the longer the utilization period of the pharmaceutical, the higher the medicinal effect of the pharmaceutical, in which case the pharmaceutical may be a pharmaceutical for maintaining the state of the injury/disease by administration.

Description

Information processing method, computer program and information processing apparatus

The present invention relates to an information processing method, a computer program, and an information processing device that support drug selection.

There are multiple drugs with the same active ingredient or the same mechanism of action that can be prescribed for injuries. For example, generic drugs that are marketed after the exclusive sales period of the original drug expires have the same active ingredients or the same mechanism of action as the original drug.

Patent Document 1 proposes a drug candidate search database server device for searching drug candidates for animals and plants. This drug candidate search database server device stores drug specific information including the name of the drug applied for the purpose of improving or preventing disease for each type of animal and plant and the name of the contained active ingredient, the purpose of the drug, the target animal and plant, and the drug efficacy. And the usage information including the usage such as usage method and the classification information including the classification code indicating the efficacy equivalence of the drug and the active ingredient are associated and stored in the database. The drug candidate search database server device searches for data on applicable drugs or applicable active ingredients based on any of the type of animal or plant, purpose, name of drug, name of active ingredient, usage or classification code, and obtains search results to the client terminal device.

Patent No. 6718186

When there are multiple drugs with the same active ingredient or the same mechanism of action, it is difficult to understand the differences between these multiple drugs, especially whether the efficacy of the drug is high or low. The drug candidate search database server device described in Patent Document 1 searches for applicable drugs from the database and displays them on the client terminal device. It is difficult to decide which one to choose.

SUMMARY OF THE INVENTION The present invention has been made in view of such circumstances, and an object thereof is to provide an information processing method, a computer program, and an information processing apparatus that can be expected to assist a user in drug selection. It is in.

In an information processing method according to one embodiment, an information processing device acquires information that associates a type of injury or disease with a usage period of a drug prescribed for the injury or disease, and based on the acquired information, Estimate the efficacy of the drug.

According to one embodiment, it can be expected to support the selection of drugs by the user.

1 is a schematic diagram for explaining an overview of an information processing system according to Embodiment 1; FIG. 1 is a block diagram showing the configuration of a server device according to an embodiment; FIG. 2 is a block diagram showing the configuration of a terminal device according to this embodiment; FIG. FIG. 4 is a schematic diagram showing an example of usage period information; 7 is a flow chart showing a procedure of a process of generating usage period information performed by the server device according to the present embodiment; FIG. 10 is a schematic diagram showing a display example of an estimation result of the efficacy of a drug. 4 is a flow chart showing a procedure of efficacy estimation processing performed by the server device according to the present embodiment. FIG. 10 is a schematic diagram for explaining an outline of an information processing system according to a second embodiment; FIG.

A specific example of the information processing system according to the embodiment of the present invention will be described below with reference to the drawings. The present invention is not limited to these exemplifications, but is indicated by the scope of the claims, and is intended to include all modifications within the meaning and scope of equivalents to the scope of the claims.

<System configuration>
FIG. 1 is a schematic diagram for explaining an outline of an information processing system according to Embodiment 1. FIG. The information processing system according to the present embodiment is a system that provides various users such as doctors, pharmacists, pharmaceutical companies, administrative agencies, and the like with information on presumed efficacy of medicines. The information processing system according to the present embodiment includes a server device 1 that performs processing for estimating the efficacy of a drug, and one or more terminal devices 3 that are used by users of the system. there is The server device 1 estimates the efficacy of the drug based on various information accumulated in the medical DB (database) 5, for example, information on the usage period of the drug.

The medical DB 5 is a database that stores and accumulates medical data, so-called RWD (Real World Data), which is obtained in daily clinical practice at medical institutions, for example. The RWD stored in the medical DB 5 includes, for example, information on medical fees (so-called receipt data), information on evaluation of medical fees by the DPC (Diagnosis Procedure Combination, diagnosis group classification) system, electronic medical records created in medical institutions, etc. Various information may be included, such as data, information about the results of a physical examination of the patient, or vital data obtained by a wearable device worn by the patient. In this embodiment, the information stored in the medical DB 5 includes at least information regarding the prescription period of the drug by the patient.

The server device 1 is a device managed and operated by a company that provides this service, etc., communicates with one or a plurality of terminal devices 3 via a network such as the Internet, and provides the above services to the terminal devices 3. Various information processing is performed to The server device 1 may be a device managed and operated by a company or the like that collects RWD, and in this case, the server device 1 may include a medical DB 5 . The terminal device 3 is an information processing device such as a personal computer used by a user such as a doctor or a pharmacist, and may be a portable information processing device such as a smart phone or a tablet terminal device.

For example, the user inputs information on a patient's injury or disease and a drug to be prescribed for this injury or disease from the terminal device 3, and requests the server device 1 to evaluate the efficacy of this drug. The server device 1 receives a drug evaluation request from the terminal device 3, and estimates the efficacy of the drug to be evaluated and other drugs having the same active ingredient or the same mechanism of action as this drug. Based on the estimation results of these multiple drugs, the server device 1 transmits to the terminal device 3, for example, information in which multiple drugs are arranged in descending order of efficacy (or lowest) as efficacy estimation information. The terminal device 3 receives the estimated efficacy information from the server device 1, displays a list of a plurality of drugs that can be prescribed to the patient in descending order of efficacy (or lowest), and presents the list to the user.

The server device 1 selects, from among various information accumulated in the medical DB 5, for example, the patient's attribute information, the patient's injury or disease, the type of drug prescribed for the injury or disease, the name of the drug, and the name of the drug. Information such as the usage period (start date and end date of usage) is extracted and acquired, and the effectiveness of the drug is estimated based on the acquired information. The server device 1 according to the present embodiment classifies a drug to be estimated into either a drug for recovering the state of injury or disease by administration or a drug for maintaining the state of injury or disease by administration. Estimate high or low efficacy in a manner suitable for classification.

For example, it can be inferred that the shorter the period of use, the higher the medicinal efficacy of a drug that is used to recover from an injury or illness, because it is believed that the shorter the period of use by the patient, the faster the recovery from the illness. Conversely, for progressive injuries, it can be inferred that the longer the period of use, the more the progression of symptoms can be suppressed, and the higher the efficacy. The server device 1 collects information about the period of use of the drug to be inferred from the medical DB 5, and calculates a value such as the median value or average value of the period of use. In addition, the server device 1 similarly calculates values such as the median duration of use for other drugs having the same medicinal ingredient or the same action mechanism, and arranges the calculated values in ascending order to find a plurality of drugs. Generating estimated efficacy information arranged in descending order of efficacy. The server device 1 transmits the generated medicinal efficacy estimation information to the terminal device 3 , thereby displaying the estimated medicinal efficacy level on the terminal device 3 . As described above, the information processing system according to the present embodiment can provide a user with information that estimates the relative efficacy of a plurality of drugs having the same active ingredient or the same mechanism of action.

<Device configuration>
FIG. 2 is a block diagram showing the configuration of the server device 1 according to this embodiment. The server device 1 according to the present embodiment includes a processing unit 11, a storage unit (storage) 12, a communication unit (transceiver) 13, and the like. In this embodiment, the explanation is given assuming that the processing is performed by one server device, but the processing may be performed by a plurality of server devices in a distributed manner.

The processing unit 11 includes an arithmetic processing unit such as a CPU (Central Processing Unit), MPU (Micro-Processing Unit), GPU (Graphics Processing Unit) or quantum processor, ROM (Read Only Memory), RAM (Random Access Memory), etc. It is configured using By reading and executing the server program 12a stored in the storage unit 12, the processing unit 11 performs various processes such as a process of acquiring information regarding the usage period of the drug from the medical DB 5 and a process of estimating the efficacy of the drug. process.

The storage unit 12 is configured using a large-capacity storage device such as a hard disk. The storage unit 12 stores various programs executed by the processing unit 11 and various data required for processing by the processing unit 11 . In the present embodiment, the storage unit 12 stores a server program 12a executed by the processing unit 11. FIG. The storage unit 12 also stores identical drug information 12b regarding drugs having the same active ingredient or the same mechanism of action, and use period information 12c regarding the use period of the drug.

In this embodiment, the server program (computer program, program product) 12a is provided in a form recorded in a recording medium 99 such as a memory card or an optical disc, and the server device 1 reads the server program 12a from the recording medium 99 and stores it. Store in section 12 . However, the server program 12a may be written in the storage unit 12 during the manufacturing stage of the server device 1, for example. Further, for example, the server program 12a may be delivered by another remote server device or the like, and the server device 1 may acquire the program through communication. For example, the server program 12 a may be recorded in the recording medium 99 and read by a writing device and written in the storage unit 12 of the server device 1 . The server program 12 a may be provided in the form of distribution via a network, or may be provided in the form of being recorded on the recording medium 99 .

The same drug information 12b is information for the server device 1 to determine which drug has the same active ingredient or the same mechanism of action. The same drug information 12b is, for example, information in which the generic name of the drug and the product name are associated with each other. In the information processing system according to the present embodiment, even if the product names are different, the server device 1 determines that drugs with the same generic name are drugs with the same active ingredient or the same mechanism of action.

The usage period information 12c is information obtained by extracting information about the usage period of the drug from the various information stored in the medical DB 5 by the server device 1. The usage period information 12c includes, for example, patient attribute information, information about the patient's injury or disease, the type of drug (generic name) prescribed for this injury or disease, the name of the drug (trade name), and the usage period of this drug. It is information in which information such as (start date and end date of use) are associated with each other. The server device 1 periodically or as needed acquires necessary information from the medical DB 5 , generates usage period information 12 c based on the acquired information, and stores it in the storage unit 12 . The server device 1 performs a process of estimating the efficacy of the drug based on the usage period information 12 c stored in the storage unit 12 .

The communication unit 13 communicates with various devices via a network N including a mobile phone communication network, a wireless LAN (Local Area Network), the Internet, and the like. In this embodiment, the communication unit 13 communicates with one or more terminal devices 3 via the network N, and communicates with the medical DB 5 (or another server device including the medical DB 5). I do. The communication unit 13 transmits the data given from the processing unit 11 to other devices, and gives the data received from the other devices to the processing unit 11 .

The storage unit 12 may be an external storage device connected to the server device 1. The server device 1 may be a multicomputer including a plurality of computers, or may be a virtual machine virtually constructed by software. The server device 1 is not limited to the above configuration, and may include, for example, a reading unit that reads information stored in a portable storage medium, an input unit that receives operation inputs, or a display unit that displays images. .

Further, in the server device 1 according to the present embodiment, the processing unit 11 reads and executes the server program 12a stored in the storage unit 12, so that the usage period information acquisition unit 11a, the efficacy estimation unit 11b, and the efficacy estimation information The output unit 11c and the like are implemented in the processing unit 11 as software functional units. In this figure, as the functional units of the processing unit 11, the functional units related to the process of estimating the efficacy of the medicine are illustrated, and the functional units related to other processes are omitted.

The usage period information acquisition unit 11a extracts and acquires information about the period during which the patient used the drug from various information stored in the medical DB 5. In this embodiment, the medical DB 5 stores RWD including various medical information. The usage period information acquisition unit 11a extracts information about a patient having a certain disease from the medical DB 5, for example, and based on the extracted information, the first prescribed time point and the last prescribed time point for a drug prescribed to each patient. By looking at the point in time when the drug was taken, the period during which this drug was prescribed to this patient, ie, the period of use of the drug, is calculated. Based on the information extracted from the medical DB 5, the usage period information acquisition unit 11a obtains, for example, the patient's attribute information (gender, age, etc.), the patient's injury or disease, and the drug prescribed for this patient's injury or disease. Information is generated that associates the type (generic name), the name (trade name) of the drug, and the period of use (start date and end date of use) of the drug, and the generated information is used in the storage unit 12. It is stored as period information 12c.

Note that in the present embodiment, the period during which the doctor prescribed the drug to the patient is used as the period of use of the drug. However, the period of use of the drug is not limited to this. For example, the period during which the patient actually took the prescribed drug (the period from the start of the drug to the end of the drug) may be used as the drug use period. Also, for example, the period during which the patient opens the medicine package containing the prescribed medicine (from the time the medicine package is first opened to the time the medicine package is finally opened) may be used as the medicine utilization period, or other periods than these. may be used as the usage period of the drug.

The efficacy estimating unit 11b performs a process of estimating the efficacy of the drug based on the usage period information 12c acquired by the usage period information acquisition unit 11a. In the present embodiment, the efficacy estimating unit 11b estimates whether the efficacy of a plurality of drugs having the same active ingredient or the same mechanism of action (a plurality of drugs having the same generic name) is relatively high or low. Information in which a plurality of drugs are arranged in order from highest (or lowest) is created as efficacy estimation information. Based on the same drug information 12b pre-stored in the storage unit 12, the efficacy estimation unit 11b can determine whether or not a plurality of drugs have the same active ingredient or the same mechanism of action.

The efficacy estimating unit 11b calculates the median value or average value of the period of use for each drug whose efficacy is to be estimated, and estimates the relative efficacy of multiple drugs based on these calculated values. At this time, the efficacy estimating unit 11b determines whether the drug whose efficacy is to be estimated is a drug for recovering the state of injury or disease by administration or a drug for maintaining the state of injury or disease by administration. do. In the case of a drug for recovering from an injury or illness by administration, the drug efficacy estimating unit 11b estimates that the shorter the median value of the calculated usage period, the higher the drug efficacy of the drug. On the other hand, in the case of a drug for maintaining the state of injury or disease by administration, the efficacy estimating unit 11b estimates that the longer the calculated median usage period, etc., the higher the efficacy of the drug.

The estimated efficacy information output unit 11c performs processing for outputting estimated efficacy information created by the efficacy estimation unit 11b as an estimation result. In the present embodiment, the estimated medicinal efficacy information output unit 11c communicates with the terminal device 3 through the communication unit 13, and transmits (outputs) the estimated medicinal efficacy information to the terminal device 3, thereby outputting the estimated medicinal efficacy information to the terminal device 3. to display (output).

FIG. 3 is a block diagram showing the configuration of the terminal device 3 according to this embodiment. The terminal device 3 according to this embodiment includes a processing unit 31, a storage unit (storage) 32, a communication unit (transceiver) 33, a display unit (display) 34, an operation unit 35, and the like. The terminal device 3 is a device used by a user such as a doctor, a pharmacist, a pharmaceutical company, or an administrative agency, for example, and may be configured using an information processing device such as a smart phone, a tablet terminal device, or a personal computer.

The processing unit 31 is configured using an arithmetic processing unit such as a CPU or MPU, a ROM, and the like. By reading and executing the program 32a stored in the storage unit 32, the processing unit 31 performs various processes such as processing for receiving input of information from the user and processing for displaying the results of estimation of drug efficacy by the server device 1. process.

The storage unit 32 is configured using, for example, a non-volatile memory device such as a flash memory or a storage device such as a hard disk. The storage unit 32 stores various programs executed by the processing unit 31 and various data required for processing by the processing unit 31 . In the present embodiment, the storage unit 32 stores a program 32a executed by the processing unit 31. FIG. In this embodiment, the program 32a is distributed by a remote server device or the like, and the terminal device 3 acquires it through communication and stores it in the storage unit 32. FIG. However, the program 32a may be written in the storage unit 32 during the manufacturing stage of the terminal device 3, for example. For example, the program 32a may be stored in the storage unit 32 after the terminal device 3 reads the program 32a recorded in the recording medium 98 such as a memory card or an optical disk. For example, the program 32 a may be recorded in the recording medium 98 and read by a writing device and written in the storage unit 32 of the terminal device 3 . The program 32 a may be provided in the form of distribution via a network, or may be provided in the form of being recorded on the recording medium 98 .

The communication unit 33 communicates with various devices via a network N including a mobile phone communication network, a wireless LAN, the Internet, and the like. In the present embodiment, the communication unit 33 communicates with the server device 1 via the network N. FIG. The communication unit 33 transmits data received from the processing unit 31 to other devices, and provides the processing unit 31 with data received from other devices.

The display unit 34 is configured using a liquid crystal display or the like, and displays various images, characters, etc. based on the processing of the processing unit 31. The operation unit 35 receives a user's operation and notifies the processing unit 31 of the received operation. For example, the operation unit 35 receives a user's operation using an input device such as mechanical buttons or a touch panel provided on the surface of the display unit 34 . Further, for example, the operation unit 35 may be an input device such as a mouse and a keyboard, and these input devices may be detachable from the terminal device 3 .

Further, in the terminal device 3 according to the present embodiment, the processing unit 31 reads out and executes the program 32a stored in the storage unit 32, so that the information acquisition unit 31a, the display processing unit 31b, etc. function as software functional units. It is implemented in the processing unit 31 . The program 32a may be a program dedicated to the information processing system according to the present embodiment, or may be a general-purpose program such as an Internet browser or web browser.

The information acquisition unit 31a performs processing for acquiring information such as injuries or medicines input by the user. The information acquisition unit 31 a displays an information input screen on the display unit 34 , for example, and receives input of illness or medicine from the user based on the user's operation on the operation unit 35 . The information acquisition unit 31a sends the acquired information about the disease or the drug to the server device 1, and requests estimation of the level of efficacy of the drug when the input drug is used for the input disease. The drug information acquired by the information acquisition unit 31a may be the generic name of the drug or the product name of the drug. The server device 1 that has received the information transmitted from the information acquisition unit 31a performs a process of estimating the degree of medicinal efficacy, and transmits the estimation result to the terminal device 3 .

The display processing unit 31b performs processing for displaying various information such as images and characters on the display unit 34. For example, the display processing unit 31b displays an input screen on the display unit 34 for the information acquisition unit 31a to receive information input by the user. Further, for example, the display processing unit 31b displays on the display unit 34 the result of estimation of the efficacy of the medicine received from the server device 1 .

<Efficacy estimation processing>
In the information processing system according to the present embodiment, various information obtained from medical institutions or the like is stored in the medical DB 5 as real world data, and the server apparatus 1 calculates the efficacy of the drug based on the information stored in the medical DB 5. Perform processing to estimate the height of Information stored in the medical DB 5 may include various information such as medical bill data or electronic medical record data. information on the usage period of the drug is extracted and acquired from the storage unit 12, and the acquired information is stored in the storage unit 12 as usage period information 12c.

At this time, the server device 1 acquires information such as drug prescription records stored in the medical DB 5, for example. of the drug was prescribed, then a month's worth of the drug was prescribed in March, and so on. , the end date of use, the period of use, etc., can be stored as the period of use information 12c in association with the information such as the name of the patient, the disease, the name of the medicine, and the like. For example, if the first month's worth of medication was prescribed on January 1, 2022, and the last month's worth of medication was prescribed on August 1, 2021, the use of this medication A period of 8 months can be considered.

In the present embodiment, the usage period of the drug is the period during which the drug is prescribed, but it is not limited to this. For example, if the medical DB 5 stores daily drug administration records for a patient hospitalized in a hospital, or information such as the patient's daily drug intake status is stored in the medical DB 5. In such a case, the server apparatus 1 may set the period during which the patient takes the medicine or the period during which the medicine package is opened by the patient based on this information as the utilization period of the medicine.

FIG. 4 is a schematic diagram showing an example of the usage period information 12c. The usage period information 12c shown in the figure is information in which "patient attribute information", "injury or disease information", "medicine information" and "period information" are associated and stored. "Patient attribute information" is information relating to a patient who has been administered a drug, and may include information such as "patient ID", "age" and "gender", for example. “Patient ID” is identification information uniquely attached to a patient. In addition to this information, the "patient attribute information" may include various information such as the patient's place of residence, medical history, or surgical history. The “injury or disease information” is information relating to the patient's injury or disease, and may include information such as “injury or disease name”, for example. In addition, the "injury or disease information" may include information such as the degree of injury or disease.

"Drug information" is information about the drug administered to the patient, and may include information such as "generic name" and "trade name". A "generic name" may be, for example, the name of the main ingredient of a drug. "Product name" is the name of a drug as a product named by a pharmaceutical company or the like that manufactures or sells the drug. In the present embodiment, drugs with different "brand names" but with the same "generic name" are drugs with the same active ingredient or the same mechanism of action. When the server device 1 can acquire the generic name and product name of the drug from the information stored in the medical DB 5, the server device 1 uses the generic name and product name acquired from the medical DB 5 as "drug information" in the usage period information 12c. On the other hand, if only the product name of the drug can be acquired from the information stored in the medical DB 5, the server device 1, based on the identical drug information 12b stored in the storage unit 12, calculates the generic name corresponding to the product name. is obtained and set as "medicine information" of the usage period information 12c.

"Period information" is information about the period during which the drug was administered to the patient, and may include information such as "use start date", "use end date", and "use period". In the information processing system according to the present embodiment, it is the "use period" that is used in the process of estimating the level of medicinal efficacy. may not be included in In addition, since the "period of use" can be calculated from the "start date of use" and the "end date of use", the "period information" includes the "start date of use" and the "end date of use", may not contain

The server device 1 repeatedly acquires information from the medical DB 5 at a predetermined cycle such as one day, one week or one month, extracts information about the usage period of the drug, and stores the extracted information in the storage unit 12 for the usage period. It is stored and accumulated as information 12c. Alternatively, the server device 1 may acquire information on the drug to be estimated from the medical DB 5 and create the usage period information 12c when performing the process of estimating the efficacy of the drug.

FIG. 5 is a flow chart showing the procedure of generation processing of the usage period information 12c performed by the server device 1 according to the present embodiment. The usage period information acquisition unit 11a of the processing unit 11 of the server device 1 according to the present embodiment acquires information from the medical DB 5 at a predetermined cycle such as one week or one month. It is determined whether or not it has reached (step S1). If the timing for acquiring information has not yet arrived (S1: NO), the usage period information acquisition unit 11a waits until the timing for acquiring information. When it is time to acquire information (S1: YES), the usage period information acquisition unit 11a accesses the medical DB 5 by communicating with the communication unit 13 via the network, and obtains various information stored in the medical DB 5. information on drug prescription is obtained from the information (step S2).

Next, the usage period information acquisition unit 11a selects one patient from many patients included in the acquired information (step S3). The usage period information acquisition unit 11a extracts the drug prescription history for the patient selected in step S3 from the information acquired from the medical DB 5 in step S2 (step S4). Based on the extracted prescription history, the usage period information acquisition unit 11a acquires the start date and end date when the target drug was prescribed to the patient for the target injury or disease (step S5). The usage period information acquiring unit 11a calculates the usage period of the drug based on the start date and end date of the prescription of the drug acquired in step S5 (step S6).

The usage period information acquisition unit 11a determines whether or not the calculation of the drug usage period has been completed for all patients included in the information acquired in step S2 (step S7). If the calculation of the usage period has not been completed for all patients (S7: NO), the usage period information acquisition unit 11a returns the process to step S3 and calculates the usage period for another patient. When the calculation of the usage period for all patients has been completed (S7: YES), the usage period information acquisition unit 11a associates the calculated usage period information with information such as patient attribute information, injury or disease information, and drug information. , is stored as the usage period information 12c in the storage unit 12 (step S8), and the process is terminated.

In the information processing system according to the present embodiment, a user can input information about an injury or disease and a drug to the terminal device 3 and request the server device 1 to estimate the efficacy of the drug. The terminal device 3 acquires the information of the disease (sickness name, disease ID, etc.) input by the user and the medicine (product name or general name), and transmits the acquired information to the server device 1 . The server device 1 that has received the information from the terminal device 3 performs a process of estimating the efficacy of the drug based on the received information on the disease and the drug.

In the present embodiment, it is assumed that the server device 1 performs processing for estimating the degree of drug efficacy in response to a request from the terminal device 3, but the present invention is not limited to this. The server device 1 acquires information from the medical DB 5 at a predetermined cycle such as one day, one week or one month, estimates the efficacy of one or more drugs each time the information is acquired, and outputs the estimation result. You can store it. The server device 1 may, for example, periodically transmit the estimation result to the terminal device 3 of a pre-registered user, or may transmit the stored estimation result to the terminal device 3 upon request from the user, for example. good.

The server device 1 according to the present embodiment, in response to a request received from the terminal device 3, performs a process of estimating the efficacy of the drug based on the usage period information 12c stored in the storage unit 12. The server device 1 acquires the drug to be estimated included in the request received from the terminal device 3, and if the drug is specified by the product name, the same drug information 12b stored in the storage unit 12 is used. Then, the generic name of this drug is obtained, and the trade name of another drug with the same generic name is obtained. In addition, when a drug is specified by a generic name, the server device 1, based on the identical drug information 12b stored in the storage unit 12, specifies the product name of one or more drugs to which the generic name is assigned. to get One or a plurality of brand name drugs acquired by the server device 1 are subject to estimation of efficacy.

It should be noted that in the present embodiment, different product names are given to the same product, such as "Drug A 2 mg (milligrams)" and "Drug A 3 mg", because the doses of the drugs are different. are treated as drugs of the same product with the product name of "medicine A", for example. For example, the server device 1 preliminarily stores information on drugs treated as the same product even if the product names are different in the same drug information 12b. can be determined. Further, for example, the server device 1 may perform a process of deleting character strings corresponding to numerical values and units from product names, and may determine drugs with the same product name from which these character strings are deleted as the same products.

The server device 1 stores, in the storage unit 12, information on prescribing one or more brand name medicines to be estimated for the injury or disease to be estimated included in the request received from the terminal device 3. Usage period information Extract from 12c. The server device 1 aggregates the extracted information for each product name of the drug, and calculates the median value of the period of use for each drug. The median value of the usage period is the value located in the middle when the usage periods are arranged in order of magnitude. In the present embodiment, the server device 1 calculates the median value of the usage period, but is not limited to this, and calculates statistical values such as average value, mode value, maximum value or minimum value. You may

In the information processing system according to the present embodiment, drugs to be estimated are classified into either of the following two types of drugs. The server device 1 pre-stores in the storage unit 12, for example, information indicating the correspondence relationship between the common name of a drug and which of the following two types the drug is classified into. Based on this information, the common name Drugs can be classified from
(1) A drug for recovering the state of injury or disease by administration (2) A drug for maintaining the state of injury or disease by administration

(1) Drugs for recovering the state of injury or disease by administration It can be estimated that the shorter the period of use, the higher the efficacy. Such medications may include, for example, medications prescribed for stomach ulcers, infections or injuries such as hepatitis C. Therefore, the server apparatus 1 compares the median value of the period of use calculated for each product name of the drug for recovering the state of injury or disease by administration, and determines that the drug with the smaller median period of use has higher efficacy. presume. The server device 1 generates, as an estimation result, information in which a plurality of drugs with the same generic name but different product names are arranged in descending order of the median usage period.

However, even if the usage period is short, if the use of the drug is terminated for reasons other than recovery from injury or illness, such as a change in the drug administered to the patient or the death of the patient, the efficacy of the drug will be lost. cannot be estimated to be high. For this reason, the server device 1 selects the use period information 12c stored in the storage unit 12 for medicines that are used to recover from injury or disease by administration, and the use period of the medicine ends for reasons other than recovery from injury or illness. from the information for estimating high or low drug efficacy. The server device 1 can determine whether the end of drug use is due to recovery from injury or illness or for reasons other than recovery based on the patient's chart data stored in the medical DB 5, for example. . It should be noted that the server device 1 determines whether or not the end of use of a medicine for recovering from an injury or disease is due to recovery from an injury or disease when acquiring the usage period information 12c from the medical DB, and determines whether the end of use is due to a reason other than recovery. may not be included in the information stored as the usage period information 12c.

(2) Drugs administered to maintain the state of injury or disease Therefore, it can be estimated that the longer the period of use, the higher the efficacy. It can be presumed that the drug to be used is changed, for example, when the doctor or the like determines that the effect on the disease is low and the doctor prescribes another drug to the patient. Such drugs may include, for example, drugs prescribed for injuries such as rheumatoid arthritis, ulcerative colitis, Crohn's disease or dementia. Therefore, the server apparatus 1 compares the median value of the period of use calculated for each product name of the drug for maintaining the state of injury or disease by administration, and considers that the drug with the larger median period of use has higher efficacy. presume. The server device 1 generates, as an estimation result, information in which a plurality of drugs with the same generic name but different product names are arranged in descending order of the median usage period.

The server device 1 transmits the result of estimating the efficacy of the drug, that is, information in which the product names of the drugs are arranged in descending order of efficacy to the terminal device 3 of the request source. The terminal device 3 receives the estimation result of the level of the drug from the server device 1 and presents the received estimation result to the user by displaying it on the display unit 34 .

FIG. 6 is a schematic diagram showing a display example of the estimation result of the level of drug efficacy. The terminal device 3 according to the present embodiment displays in the left area of the screen that the "generic name" of the drug to be estimated is "drug A", and in the central area of the screen, a plurality of drugs with the same generic name ( That is, the "trade names" of the same medicinal ingredients or drugs with the same mechanism of action) are arranged in the vertical direction and displayed as a list. In the illustrated example, 11 product names of "drug a1" to "drug a11" are listed as a plurality of drugs having the same active ingredient or the same mechanism of action.

In addition, the terminal device 3 displays a graph indicating the usage period (prescription period) of each drug in the right area of the screen in association with the product name of each drug. In the illustrated example, the terminal device 3 collects usage period information for each drug from the usage period information 12c, and plots the collected information on a one-dimensional scatter diagram with the horizontal axis representing the period for each drug product name. to generate and display. In addition, the terminal device 3 displays the median value of the usage period of each graph in an overlapping manner. In the illustrated example, the median usage period of "medicine a1" is 546, and the median usage period of "medicine a2" is 460.

The example shown in the figure is an estimation result related to a drug for maintaining the state of injury or disease by administration. The drug names and graphs of a plurality of drugs are arranged and displayed in descending order of the median usage period from top to bottom, with smaller drugs (that is, drugs with lower efficacy) on the lower side. Although illustration is omitted, in the case of displaying the estimated results of medicines for recovering from an injury or illness by administration, the terminal device 3 arranges and displays the results in descending order of the median usage period from top to bottom. .

Based on the estimation results displayed by the terminal device 3, the user can determine which of the multiple drugs with the same generic name but different brand names has high efficacy and which has low efficacy. That is, it is possible to judge the relative efficacy of a plurality of drugs.

FIG. 7 is a flow chart showing the procedure of the efficacy estimation process performed by the server device 1 according to the present embodiment. The efficacy estimating unit 11b of the processing unit 11 of the server device 1 according to the present embodiment determines whether or not it has received a request from the terminal device 3 to perform the process of estimating the efficacy of the drug (step S21). If the request for the estimation process has not been received (S21: NO), the efficacy estimation unit 11b waits until the request is received from the terminal device 3.

When the request for the estimation process is received (S21: YES), the efficacy estimation unit 11b selects from the information on various drugs included in the usage period information 12c stored in the storage unit 12, in the request from the terminal device 3 Information corresponding to (the generic name of) the designated target drug is acquired (step S22). Based on the information acquired in step S22, the efficacy estimation unit 11b aggregates the duration of use corresponding to each drug (product name) (step S23), and calculates the median value of the duration of use for each drug (step S24).

The efficacy estimating unit 11b determines whether or not the target drug specified in the request from the terminal device 3 is a drug for recovering from an injury or illness by administration (step S25). If the drug is for recovering from an injury or illness (S25: YES), the drug efficacy estimating unit 11b, based on the median value of the duration of use for each drug calculated in step S24, sequentially Information in which drugs are arranged is created (step S26), and the process proceeds to step S28. If the drug is not for recovering from the injury or disease (S25: NO), the efficacy estimating unit 11b selects the drug in descending order of the median duration of use for each drug calculated in step S24. are arranged (step S27), and the process proceeds to step S28. The medicinal efficacy estimation information output unit 11c of the processing unit 11 transmits the information on the medicinal efficacy estimation results created in step S26 or S27 to the terminal device 3 that is the request source (step S28), and ends the process.

<Summary>
In the information processing system according to the present embodiment having the configuration described above, the server device 1 acquires information that associates a drug prescribed for an injury or illness with a usage period of the drug from the medical DB 5, and the acquired information Based on this, the server device 1 performs a process of estimating the degree of efficacy of the drug. Thereby, the user can select the drug to be used based on the efficacy of the drug estimated by the server device 1 . The information processing system according to the present embodiment can be expected to support the selection of drugs by the user.

In addition, in the information processing system according to the present embodiment, the server device 1 estimates that the shorter the usage period of the drug, the higher the drug efficacy. As a result, the server device 1 can be expected to accurately estimate the degree of efficacy of a drug for recovering from an injury or illness when administered. In addition, the server device 1 excludes information when the use of the medicine is stopped due to factors other than recovery, and estimates the level of efficacy of the medicine. As a result, the server device 1 can be expected to more accurately estimate the level of efficacy.

In addition, in the information processing system according to the present embodiment, the server device 1 estimates that the longer the usage period of the drug, the higher the drug efficacy. As a result, the server device 1 can be expected to accurately estimate the degree of efficacy of a drug that is administered to maintain the state of an injury or disease.

In addition, in the information processing system according to the present embodiment, the relative efficacy of a plurality of drugs having the same active ingredient or the same mechanism of action is estimated, and the estimated efficacy of each drug is determined, for example, by a drug having a high efficacy. The drugs are displayed side-by-side in (or in descending) order and displayed in a list. This allows the user to easily comprehend the relative efficacy of multiple drugs with the same active ingredient or the same mechanism of action.

In addition, in the information processing system according to the present embodiment, the server device 1 estimates the degree of efficacy of a plurality of drugs with the same name but different volumes as the same drug. As a result, the server device 1 can prevent estimating the level of efficacy of substantially the same drug as different drugs.

In addition, in the information processing system according to the present embodiment, the server device 1 estimates the degree of efficacy of the drug by regarding the period during which the doctor prescribes the drug as the period of use of the drug. As a result, the server device 1 can be expected to accurately estimate the efficacy of the drug based on the information such as the prescription record of the drug stored in the medical DB 5 .

In the present embodiment, the server device 1 is configured to acquire information from the medical DB 5 by communication via a network, but the present invention is not limited to this. may be collected. Further, in the present embodiment, the server device 1 is configured to perform processing for estimating the level of efficacy of a drug in response to a request from the terminal device 3, but the present invention is not limited to this. For example, the server device 1 performs a process of estimating the efficacy of a plurality of drugs at a predetermined cycle regardless of whether or not there is a request from the terminal device 3, and periodically transmits information about the estimation results to the terminal device 3. may

In addition, in the present embodiment, information obtained by arranging a plurality of drugs in descending order of efficacy (or lowest) is used as the estimation result, but the information is not limited to this. For example, the server device 1 may calculate a numerical value such as a ranking or a deviation value regarding the level of efficacy of a target drug among a plurality of drugs having the same active ingredient or the same mechanism of action, and the calculated numerical value may be used as the estimation result of the level of efficacy. . In addition, in the present embodiment, the estimation result is the relative effectiveness of a plurality of drugs with the same active ingredient or the same mechanism of action compared with the period of use, but the present invention is not limited to this. The level of drug efficacy may be estimated by comparing a value such as a value with a predetermined threshold value.

<Embodiment 2>
The information processing system according to Embodiment 2 is configured such that the server device 1 collects information on the period of use of the drug by the patient. FIG. 8 is a schematic diagram for explaining an outline of an information processing system according to the second embodiment. In the information processing system according to the second embodiment, the drug taken by the patient is, for example, a drug in the form of powdered drug enclosed in a capsule, and the sensor 7 is enclosed in the capsule together with the drug. The capsule is made of a material that dissolves in the patient's body, and when the capsule dissolves in the patient's body, the sensor 7 comes into contact with gastric juice or the like. The sensor 7 is provided with, for example, two exposed electrodes, and the sensor 7 detects that the two electrodes are electrically connected via gastric juice or the like. The sensor 7 has a function of transmitting a wireless signal, and transmits a wireless signal to the terminal device 8 existing outside the patient's body when it detects that the two electrodes are electrically connected.

The terminal device 8 is, for example, a communication device attached to the patient's body, or an information processing device such as a smartphone used by the patient, and is capable of receiving wireless signals transmitted by the sensor 7. When receiving the radio signal from the sensor 7, the terminal device 8 stores information such as the date and time when the radio signal was received and the name of the drug taken by the patient. In addition, the terminal device 8 stores the stored information with information such as a patient ID, etc., as drug utilization information, and uses it at an appropriate timing, for example, once a day, or receives a wireless signal from the sensor 7. is transmitted to the server device 1 each time it receives the

The server device 1 according to Embodiment 2 includes a medical DB 5. When receiving the drug use information from the terminal device 8 , the server device 1 stores and accumulates the received drug use information in the medical DB 5 . The server device 1 can perform a process of calculating the period of use of the drug based on the drug use information stored in the medical DB 5 and estimating the level of efficacy of the drug based on the calculated period of use.

In the information processing system according to the second embodiment having the above configuration, the sensor 7 enclosed in the capsule detects the drug intake by the patient, and the terminal device 8 transmits the drug use information based on the detection result of the sensor 7 to the server device 1. , and the server device 1 stores the drug use information in the medical DB 5 . The server device 1 calculates the usage period of the drug based on the drug use information stored in the medical DB 5, and estimates the degree of efficacy of the drug. As a result, the server device 1 can more accurately calculate the duration of use of the medicine by the patient, and therefore it can be expected to improve the accuracy of estimating the effectiveness of the medicine.

(Modification)
In the information processing system according to the second embodiment described above, the sensor 7 enclosed in a drug capsule is used to detect drug ingestion by the patient, but the method of detecting drug ingestion is not limited to this. In the information processing system according to the modification, a sensor is provided in the medicine package that wraps the medicine, and the sensor detects opening of the medicine package. The sensor that detects the opening transmits a radio signal, and the terminal device 8 that receives the radio signal stores information such as the date and time when the medicine package was opened and the name of the medicine taken by the patient. The terminal device 3 adds information such as a patient's ID to the stored information, and transmits the information to the server device 1 as drug use information. The server device 1 receives the drug use information from the terminal device 8, stores it in the medical DB 5, calculates the drug use period based on the drug use information stored in the medical DB 5, and uses the drug based on the calculated use period. Estimate high and low drug efficacy.

In addition, in Embodiment 2 and its modification, the server device 1 that performs the process of estimating the level of drug efficacy of a drug is configured to include the medical DB 5, but the present invention is not limited to this. A server device different from the server device 1 that performs the estimation process may have the medical DB 5 , and this server device may receive the drug use information from the patient's terminal device 8 and store it in the medical DB 5 . The server device 1 that performs the estimation process can acquire the drug utilization information stored in the medical DB 5 and use it for the estimation process by communicating with the server device having the medical DB 5 via a network.

In addition, since other configurations of the information processing system according to Embodiment 2 are the same as those of the information processing system according to Embodiment 1, similar parts are denoted by the same reference numerals, and detailed description thereof will be omitted.

The embodiments disclosed this time are illustrative in all respects and should be considered not restrictive. The scope of the present invention is indicated by the scope of the claims rather than the meaning described above, and is intended to include all changes within the meaning and scope equivalent to the scope of the claims.

1 server device (information processing device)
3 terminal device 5 medical DB
7 sensor 8 terminal device 11 processing unit 11a usage period information acquisition unit (acquisition unit)
11b Efficacy estimation part (estimation part)
11c Efficacy estimation information output unit 12 Storage unit 12a Server program (computer program)
12b same drug information 12c use period information 13 communication unit 31 processing unit 31a information acquisition unit 31b display processing unit 32 storage unit 32a program 33 communication unit 34 display unit 35

operation unit

98, 99 recording medium N network

Claims

The information processing device
Acquire information that associates the drug prescribed for the injury and the period of use of the drug,
estimating the efficacy of the drug based on the acquired information;
Information processing methods.
The information processing device estimates that the shorter the period of use of the drug, the higher the efficacy of the drug.
The information processing method according to claim 1 .
The drug is a drug for recovering the state of injury or disease by administration,
The information processing device excludes information when use is discontinued due to factors other than recovery from the acquired information, and estimates the efficacy of the drug.
The information processing method according to claim 2.
The information processing device estimates that the longer the period of use of the drug, the higher the efficacy of the drug,
The information processing method according to claim 1 .
The drug is a drug for maintaining the state of injury or disease by administration,
The information processing method according to claim 4.
The information processing device
Estimating the efficacy of multiple drugs with the same active ingredient or the same mechanism of action,
Contrasting and displaying the estimated effectiveness of each drug,
The information processing method according to any one of claims 1 to 5.
The information processing device regards a plurality of drugs with the same name but different volumes as the same drug, and estimates the efficacy of the drug.
The information processing method according to claim 6.
The usage period is the period during which the doctor prescribed the drug, the period during which the patient took the drug, or the period during which the patient opened the drug.
The information processing method according to any one of claims 1 to 7.
The drug contains a sensor that detects ingestion by the patient,
The information processing device acquires information including the usage period of the drug based on the detection result of the sensor, and estimates the level of efficacy of the drug.
The information processing method according to any one of claims 1 to 8.
The drug package enclosing the drug is provided with a sensor for detecting opening,
The information processing device acquires information including the usage period of the drug based on the detection result of the sensor, and estimates the level of efficacy of the drug.
The information processing method according to any one of claims 1 to 8.
to the computer,
Acquire information that associates the type of injury and disease with the period of use of the drug prescribed for the injury,
A computer program for executing a process of estimating the efficacy of the drug based on the obtained information.
an acquisition unit that acquires information that associates the type of injury or disease with the usage period of the drug prescribed for the injury or disease;
An information processing apparatus comprising: an estimation unit for estimating the efficacy of the drug based on the obtained information.