WO2023113178A1

WO2023113178A1 - Method and system for analyzing microparticles of cells or microorganisms

Info

Publication number: WO2023113178A1
Application number: PCT/KR2022/015336
Authority: WO
Inventors: 조홍; 태석호; 김상훈; 김지혜
Original assignee: 조홍
Priority date: 2021-12-16
Filing date: 2022-10-12
Publication date: 2023-06-22

Abstract

A method for analyzing microparticles of cells or microorganisms according to one embodiment of the present invention may comprise the steps in which: a communication unit receives a captured image of target particles from a portable terminal; a calculation unit calculates calculation information on the type and number of the target particles using the captured image and external data of microparticles stored in advance; a processing unit generates result information by mapping the calculation information onto the captured image.

Description

Cell or microorganism fine particle analysis method and system

The present invention relates to a method and system for analyzing fine particles of cells or microorganisms, and more particularly, to a method and system for analyzing fine particles of cells or microorganisms for analyzing the type and number of fine particles such as cells or microorganisms.

Various types of microorganisms present in the human body can affect human diseases by closely interacting with human cells and tissues like organisms.

In particular, the genes, proteins, and metabolites of microorganisms in the human body cause abnormal reactions with human gene expression or tissue cells, and cause immune system disturbances to cause diseases.

Therefore, in recent years, a technology for diagnosing diseases by measuring changes in the distribution and genetic changes of microorganisms present in the human body has emerged as an important issue.

In addition, not only disease diagnosis using microorganisms, but also various treatment methods based on microorganisms such as immuno-cancer drugs are being studied.

In order to measure the distribution and change of microorganisms in the human body, a method of extracting DNA and analyzing genes, a naked eye or microscopic examination using feces, and a bacterial culture test have been conventionally performed.

1 shows a conventional method for analyzing microparticles of cells or microorganisms, which requires a person to classify cells or microorganisms cultured in a petri dish by type and count the number of cells or microorganisms.

Meanwhile, Korean Patent Publication No. 10-2001-0017092 A (Mar. 5, 2001) discloses a method for automatically analyzing and counting the shape of blood cells.

However, there is a problem that the user cannot easily recognize the analysis result of the cells analyzed on the input image, since the analysis result is simply provided through the method of automatically analyzing and counting the morphology of blood cells.

The present invention is to solve the above problems, and it is possible to very easily analyze fine particles of cells or microorganisms using a user's terminal without the need for an expensive analysis device, and the user can easily recognize the analysis result. It is intended to provide a method and system for analyzing fine particles of cells or microorganisms.

The problem to be solved by the present invention is not limited to the above-mentioned problems, and problems not mentioned will be clearly understood by those skilled in the art from this specification and the accompanying drawings. .

A method for analyzing fine particles of cells or microorganisms according to an embodiment of the present invention includes the steps of receiving a photographed image of a target particle from a mobile terminal by a communication unit; Calculating calculation information on the type and number of target particles using the captured image and external data of fine particles stored in advance by a calculation unit; generating result information by a processing unit by mapping the calculated information onto the photographed image; and transmitting the result information to the portable terminal by the communication unit.

According to the method and system for analyzing fine particles of cells or microorganisms according to an embodiment of the present invention, it is possible to analyze fine particles of cells or microorganisms very easily using a user's terminal without the need for an expensive analysis device, and the user can It has the advantage of being able to easily recognize the analysis results.

Effects of the present invention are not limited to the above-mentioned effects, and effects not mentioned will be clearly understood by those skilled in the art from this specification and the accompanying drawings.

1 is a schematic diagram for explaining a conventional method for analyzing microparticles of cells or microorganisms.

2 is a schematic view showing that a system for analyzing fine particles of cells or microorganisms embodying a method for analyzing fine particles of cells or microorganisms according to an embodiment of the present invention communicates with a data server and a portable terminal of a user.

Figure 3 is a schematic configuration block diagram of a system for analyzing fine particles of cells or microorganisms implementing the method for analyzing fine particles of cells or microorganisms according to an embodiment of the present invention.

Figure 4 is a schematic diagram for explaining a photographic image taken of cultured microparticles of the method for analyzing microparticles of cells or microorganisms according to an embodiment of the present invention.

5 is a schematic diagram for explaining result information of a method for analyzing fine particles of cells or microorganisms according to an embodiment of the present invention.

6 and 7 are schematic diagrams for explaining feedback result information of a method for analyzing microparticles of cells or microorganisms according to an embodiment of the present invention.

8 is a schematic view illustrating a second captured image to explain a method for analyzing microparticles of cells or microorganisms according to another embodiment of the present invention.

9 is a schematic diagram for explaining result information of a method for analyzing microparticles of cells or microorganisms according to another embodiment of the present invention.

10 is a schematic flowchart of a method for analyzing microparticles of cells or microorganisms according to one embodiment and another embodiment of the present invention.

Hereinafter, specific embodiments of the present invention will be described in detail with reference to the drawings. However, the spirit of the present invention is not limited to the presented embodiments, and those skilled in the art who understand the spirit of the present invention may add, change, delete, etc. other elements within the scope of the same spirit, through other degenerative inventions or the present invention. Other embodiments included within the scope of the inventive idea can be easily proposed, but it will also be said to be included within the scope of the inventive concept.

In addition, the result information includes an identification icon displaying the target particle calculated by the calculation unit on the photographed image, and the identification icon may be displayed differently for each type of target particle.

In addition, the step of receiving the selection information of the identification icon from the mobile terminal by the communication unit; generating, by the processing unit, feedback result information displaying only target particles corresponding to the identification icon selected on the photographed image; and transmitting, by the communication unit, the feedback result information to the portable terminal.

In addition, the result information may include a discrimination icon for displaying target particles that the calculation unit could not calculate on the photographed image.

In addition, the step of receiving the selection information of the distinction icon from the mobile terminal by the communication unit; calculating a degree of similarity between the target particle calculated by the calculation unit and the target particle that has not been calculated corresponding to the selected discrimination icon; generating, by the processing unit, feedback result information indicating a degree of similarity calculated on the photographed image; and transmitting, by the communication unit, the feedback result information to the portable terminal.

A system for analyzing fine particles of cells or microorganisms according to an embodiment of the present invention includes a communication unit for receiving a photographed image of a target particle from a portable terminal; a calculation unit for calculating calculation information on the type and number of target particles using the previously stored external data of the fine particles and the captured image; and a processing unit generating result information by mapping the calculated information onto the photographed image, wherein the communication unit may transmit the result information to the portable terminal.

A method for analyzing microparticles of cells or microorganisms according to another embodiment of the present invention includes receiving, by a communication unit, a first captured image of a target particle at a first time point from a portable terminal; Calculating first calculation information about the type and number of target particles using the first photographed image and external data of fine particles stored in advance by a calculation unit; receiving, by the communication unit, a second captured image of a target particle at a second point in time after the first point in time from the portable terminal; and calculating, by the calculation unit, second calculation information about the type and number of target particles in the second captured image by using the first and second captured images.

In addition, the calculating of the second calculation information may include using the first calculation information for the first captured image when the similarity between the first captured image and the target particle on the second captured image is equal to or greater than a preset similarity. The second calculation information for the second captured image is calculated, and when the similarity between the first captured image and the target particle on the second captured image is less than a preset similarity, the previously stored external data of the fine particles and the second The second calculation information may be calculated using the photographed image.

In addition, generating result information by mapping the second calculation information onto the second photographed image by a processing unit; and transmitting, by the communication unit, the result information to the mobile terminal, wherein the generating of the result information is performed on the second captured image by using the first calculated information on the first captured image. When the second calculation information for the second captured image is calculated, the result information obtained by overlapping the first captured image with the second captured image may be generated.

A system for analyzing fine particles of cells or microorganisms according to another embodiment of the present invention includes a communication unit for receiving a first photographed image of a target particle at a first time point from a portable terminal; and a calculation unit configured to calculate first calculation information on the type and number of target particles using previously stored external data of fine particles and the first photographed image, wherein the communication unit receives information from the portable terminal after the first point in time. Receives a second captured image of the target particle at a second point in time when , and the operation unit performs a second calculation on the type and number of target particles in the second captured image using the first and second captured images. information can be derived.

Elements having the same function within the scope of the same idea appearing in the drawings of each embodiment are described using the same reference numerals.

2 is a schematic diagram illustrating that a system for analyzing fine particles of cells or microorganisms embodying a method for analyzing fine particles of cells or microorganisms according to an embodiment of the present invention communicates with a data server and a portable terminal of a user.

3 is a schematic configuration block diagram of a system for analyzing fine particles of cells or microorganisms implementing the method for analyzing fine particles of cells or microorganisms according to an embodiment of the present invention.

5 is a schematic diagram for explaining result information of a method for analyzing microparticles of cells or microorganisms according to an embodiment of the present invention.

8 is a schematic diagram illustrating a second captured image to explain a method for analyzing microparticles of cells or microorganisms according to another embodiment of the present invention.

In the accompanying drawings, in order to more clearly express the technical idea of the present invention, parts that are not related to the technical idea of the present invention or can be easily derived from those skilled in the art are simplified or omitted.

Throughout the specification, when a part is said to be "connected" to another part, this includes not only the case where it is "directly connected" but also the case where it is "electrically connected" with another element interposed therebetween. . In addition, when a part "includes" a certain component, this means that it may further include other components, not excluding other components, unless otherwise stated, and one or more other characteristics. However, it should be understood that it does not preclude the possibility of existence or addition of numbers, steps, operations, components, parts, or combinations thereof.

In this specification, a "unit" includes a unit realized by hardware, a unit realized by software, and a unit realized using both. Further, one unit may be realized using two or more hardware, and two or more units may be realized by one hardware.

In this specification, some of the operations or functions described as being performed by a terminal or device may be performed instead by a server connected to the terminal or device. Likewise, some of the operations or functions described as being performed by the server may also be performed in a terminal or device connected to the corresponding server.

A method for analyzing fine particles of cells or microorganisms according to an embodiment of the present invention is a method for analyzing the number and/or type of fine particles such as animal/plant cells or microorganisms such as Escherichia coli, yeast, and actinomycetes.

Conventionally, fine particles were analyzed using an expensive analysis device, but the present invention simply analyzes a photographed image of fine particles taken using a user's portable terminal (P) to provide the user with the result of analyzing the fine particles There are advantages.

Hereinafter, with reference to FIGS. 2 to 7 and 10, a method for analyzing microparticles of cells or microorganisms according to an embodiment of the present invention will be described in more detail.

As an example, FIG. 2 shows that the system 10 for analyzing fine particles of cells or microorganisms implementing the method for analyzing fine particles of cells or microorganisms communicates with a portable terminal P and a data server D of a user. .

As shown in FIG. 2, the cell or microbe fine particle analysis system 10 can transmit and receive predetermined data/information with the user's portable terminal P, and also with the data server D. information can be transmitted and received.

For example, the user's portable terminal P may be a smart phone or a tablet PC having a touch display, but is not limited thereto.

As an example, the data server (D) refers to a server that stores information about cells or microorganisms, and refers to an external server that stores in advance the type, image, size, shape, and/or characteristics of cells or microorganisms. can

As an example, as shown in FIG. 3, the cell or microorganism fine particle analysis system 10 includes a mobile terminal P and a data server D and data necessary to implement the cell or microorganism fine particle analysis method. / The communication unit 200 for transmitting and receiving information, the memory unit 300 for storing the data / information necessary to implement the method for analyzing the fine particles of the cells or microorganisms, the data necessary for implementing the method for analyzing the fine particles of the cells or microorganisms / A display unit 400 for displaying information, an input unit 500 for receiving data/information/calculations, etc. required to implement the method for analyzing fine particles of cells or microorganisms from a manager, and a method for analyzing fine particles of cells or microorganisms It may include a processor 100 that calculates and processes data/information necessary for implementation.

For example, the processor 100 may include a calculation unit 110 and a processing unit 120 which will be described in more detail below.

Hereinafter, with reference to FIGS. 4 to 7 and 10, a method for analyzing microparticles of cells or microorganisms according to an embodiment of the present invention will be described in more detail.

FIG. 4 describes a photographed image (C) of a cell or microorganism (target particle), which is an analysis target cultured in a petri dish, by a user using his/her portable terminal (P), and FIG. 4 (a) As shown in , the target particle (a) on the captured image (C) may be a single type of cell or microorganism, and as shown in FIG. 4 (b), the target particles (a1, a2, a3) may be several types of cells or microorganisms.

Hereinafter, for convenience of explanation, as shown in FIG. I will assume and explain.

For example, the method for analyzing microparticles of cells or microorganisms may include a step (S10) of receiving, by the communication unit 200, a captured image C of target particles from a portable terminal P.

That is, the user generates the photographed image C by photographing the target particle as shown in FIG. can be sent to

Here, as an example, in the method for analyzing fine particles of cells or microorganisms, the calculation unit 110 calculates calculation information on the type and number of target particles using the captured image C and external data of fine particles stored in advance. It may further include a step (S12) of doing.

To explain this in more detail, the calculation unit 110 can acquire (S11) information (external data) on a number of fine particles from the data server D through the communication unit 200, and the data server D It is possible to define/calculate the type of target particle by comparing a number of fine particles obtained from the target particle on the photographed image (C), and the calculation information can be generated by calculating the number for each type.

For example, the calculation unit 110 obtains information on a large number of fine particles from the data server D in advance and turns it into big data, and in Korean Patent Publication No. 10-2001-0017092 A (2001.03.05) described above The calculation information may be generated by calculating the type and number of target particles in the captured image C through the disclosed artificial neural network or a previously known artificial intelligence technique.

Here, as an example, the method of analyzing microparticles of cells or microorganisms includes the steps of, by the processing unit 120, mapping the calculation information onto the captured image C to generate result information B (S13) and the communication unit (200) may further include a step (S14) of transmitting the result information (B) to the portable terminal (P).

For example, the processing unit 120 maps the calculation information generated by the calculation unit 110 onto the captured image C so that the user can easily recognize the calculation information to generate the result information B. can be config.

That is, the result information (B) may refer to information displayed at a predetermined position of the calculation information based on the photographed image (C).

To explain this in more detail, FIG. 5 is an example of the result information (B) displayed on the user's portable terminal (P), and the processing unit 120 is defined as 'OO type' by the operation unit 110 / The calculated name and number of the first target particles (a1) and the calculated name and number of the second target particles (a2) are defined as 'ΔΔ species' by the calculation unit 110/ It is possible to generate the result information (B) capable of discriminating the number of unknown third target particles (a3) that have not been calculated.

For example, the result information (B) includes an identification icon (I) indicating the target particle calculated by the calculation unit 110 on the photographed image (C), and the identification icon (I) is It may be displayed differently for each type.

That is, as shown in FIG. 5, in the result information (B), the first identification icon (I1) identifying the first target particle (a1) defined/calculated as 'OO species' is the captured image (C). ), which can be displayed on the edge of the first target particle (a1) (for example, displayed as a red box or a box with a two-dot chain line), and defined / calculated as 'ΔΔ species' The second target A second identification icon (I2) identifying the particle (a2) is displayed on the border of the second target particle (a2) on the photographed image (C) (for example, displayed as a blue box or a box with a chain line) ) may be information.

Therefore, the user determines the position of the first target particle a1 defined/calculated as 'OO species' on the captured image C through the result information B displayed on the user's portable terminal P, The position and number of the second target particles a2 defined/calculated by the number and 'ΔΔ species' can be easily recognized.

In addition, the result information (B) is a discrimination icon (K ), and the discrimination icon (K) may be displayed differently from the identification icon (I).

That is, as shown in FIG. 5, the result information (B) is used to distinguish the unknown third target particle a3, which is not defined/calculated as a specific species, from other fine particles. ) may be information displayed on the edge of the third target particle (a3) on the captured image (C) (for example, displayed as a green dotted line box or a dotted line box) there is.

Therefore, the user easily recognizes the location and number of unknown target particles that are not defined/calculated as a specific species on the captured image (C) through the result information (B) displayed on the user's portable terminal (P). can do

Here, as an example, in the method for analyzing fine particles of cells or microorganisms, the communication unit 200 receives selection information of the identification icon (I) from the portable terminal (P) or the communication unit 200 receives the selection information of the portable terminal ( A step (S15) of receiving selection information of the distinction icon K from P) may be further included.

To explain this in more detail, the user may select the identification icon (I) by touching/inputting it in the result information (B) displayed as shown in FIG. ) can be selected by touching/inputting.

For example, when the user touches and selects the first identification icon I1 among the identification icons I, the communication unit 200 selects the first identification icon I1 from the portable terminal P. The selection information may be received.

In addition, when the user touches and selects the distinction icon (K) among the identification icon (I) and the distinction icon (K), the communication unit 200 receives the first identification icon (I1) from the portable terminal (P). ) can be received.

Here, as an example, when the communication unit 200 receives the selection information of the identification icon (I), the method for analyzing fine particles of cells or microorganisms has the processing unit 120 selected on the captured image (C). Generating feedback result information (F) displaying only target particles corresponding to the identification icon (I) (S17) and transmitting the feedback result information (F) to the mobile terminal (P) by the communication unit 200 A step (S18) of doing may be further included.

To explain this in more detail, if the selection information is information for selecting the first identification icon I1, the processing unit 120 corresponds to the first identification icon I1 selected on the captured image C. The feedback result information F may be generated with only the first target particle a1 being displayed, and the second target particle a2 and the third target particle a3 deleted.

That is, FIG. 6 is an example of the feedback result information (F) displayed on the user's portable terminal (P) to explain the previous example. Only the first target particle a1 corresponding to 1 identification icon I1 may be displayed, and the second target particle a2 and the third target particle a3 may be deleted and provided to the user.

As a result, the user can easily recognize the location and number of fine particles of a specific species selected by the user.

Meanwhile, as an example, when the communication unit 200 receives the selection information of the discrimination icon K, the method for analyzing fine particles of cells or microorganisms is based on the target particle calculated by the calculation unit 110 and the selected discrimination icon. Calculating the similarity between (K) and the corresponding uncalculated target particles (S16), generating feedback result information (F) displaying the similarity calculated on the photographed image (C) by the processing unit 120 Step S17 and step S18 of transmitting the feedback result information F to the portable terminal P by the communication unit 200 may be further included.

To explain this in more detail, if the selection information is the information for selecting the discrimination icon K, the calculation unit 110 calculates the calculation information in the previous step (S12) of the target particle defined/calculated as a specific species. (For example, a1 and a2 particles) and an unknown target particle (eg, a3 particle) that is not defined/calculated as a specific species corresponding to the discrimination icon (K) are compared to calculate the degree of similarity between them. can do.

Here, the degree of similarity is the degree of similarity between shapes, colors, and images between particles. A similarity calculation formula may be pre-determined by a manager, or a known image similarity calculation technique may be applied.

Also, the processing unit 120 may generate the feedback result information F obtained by mapping the similarity calculated by the calculation unit 110 onto the photographed image C.

7 is an example of the feedback result information (F) displayed on the user's portable terminal (P), when selection information of the distinction icon (K) is received, the feedback result information (F) is the captured image (C) The feedback result in which only the third target particle a3 corresponding to the selected discrimination icon K is displayed, and the second target particle a2 and the third target particle a3 are deleted. Information (F) can be created.

In addition, the feedback result information (F) is a similarity between the third target particle (a3) and the first target particle (a1) for each of the third target particle (a3) on the photographed image (C), The similarity between the third target particle a3 and the second target particle a2 may be information displayed.

As a result, the user can easily recognize how similar the unknown target particle defined/calculated as a specific species is to the target particle defined/calculated as a specific species in the current situation.

Meanwhile, identification information of the mobile terminal P, the captured image C, the calculation information, the result information B, and the feedback information may be stored in the memory unit 300 .

Hereinafter, with reference to FIGS. 8 to 10 , a method and system 10 for analyzing microparticles of cells or microorganisms as an additional embodiment of the present invention will be described.

For contents that are duplicated with the above description or can be easily derived from the viewpoint of those skilled in the art, the description will be omitted or simplified.

As an example, the method for analyzing fine particles of cells or microorganisms may refer to a method of efficiently analyzing target particles when photographed images of target particles are acquired multiple times with a time difference.

That is, since the shape and/or size of target particles cultured in one petri dish may change over time, a method for analyzing target particles more efficiently is required.

For example, the method of analyzing microparticles of cells or microorganisms includes the steps of the communication unit 200 receiving a first captured image C of target particles at a first point in time from a portable terminal P, and the operation unit 110 Calculating first calculation information on the type and number of target particles using the previously stored external data of the fine particles and the first photographed image (C).

Here, the step of receiving the first captured image C corresponds to the step of receiving the captured image C described above (S10), and the step of calculating the first calculation information calculates the calculation information described above. It may be a step corresponding to the step (S12).

Meanwhile, similarly, the processing unit 120 generates the result information (B) for the first captured image (C) (S13) and the communication unit 200 transmits the result information (B). (S14) may be implemented.

That is, all of the fine particle analysis methods described above may be implemented (for example, steps S10 to S18 are implemented) using the first captured image (C).

On the other hand, the method of analyzing fine particles of cells or microorganisms includes the step of receiving, by the communication unit 200, a second captured image C2 of target particles at a second time point after the first time point from the portable terminal P ( S20) may be further included.

For example, when it is assumed that the first captured image C is the image of FIG. 4(b) described above, the second captured image C2 is a target particle of FIG. 4(a) different from the target particle of FIG. 4(b). ), or the image of the target particle of FIG. 8 after the target particle of FIG. 4(b) has been cultured for two days.

Meanwhile, in the method of analyzing fine particles of cells or microorganisms, the calculation unit 110 uses the first captured image C and the second captured image C2 to determine the size of the target particle on the second captured image C2. It may further include calculating second calculation information about the type and number (S21).

To explain this in more detail, in the step of calculating the second calculation information (S21), when the similarity between the first captured image C and the target particle on the second captured image C2 is equal to or greater than a preset similarity, the first The second calculation information for the second captured image C2 is calculated using the first calculation information for the captured image C, and the first captured image C and the second captured image C2 are calculated. ) If the similarity of the target particle on the image is less than the preset similarity, the second calculation information may be calculated using previously stored external data of fine particles and the second captured image C2.

That is, when the calculation unit 110 acquires the second captured image C2 from the portable terminal P through the communication unit 200, the first captured particle is the same as the target particle on the second captured image C2. A similarity between target particles in the first captured image C obtained from the portable terminal P may be calculated.

For example, the degree of similarity here is a value for determining whether the target particles on the first captured image C and the target particles on the second captured image C2 are target particles cultured in the same petri dish, and the calculation unit (110) After calculating the center point of the target particle in the first captured image C and the center point of the target particle in the second captured image C2, the arrangement relationship between the center points (disposition position, distance between dots, etc.) ), the degree of similarity can be digitized to calculate the degree of similarity. Meanwhile, the calculation unit 110 may calculate the similarity of two images using a known technique for calculating the similarity.

In addition, the preset similarity may be set in advance by an administrator, and may be set to 95%, for example.

Here, as an example, the calculation unit 110 calculates the first captured image C when the similarity between the target particles on the second captured image C2 is equal to or greater than a preset similarity. The second calculation information for the second captured image C2 may be calculated using the first calculation information.

That is, the first captured image C is the image of FIG. 4(b) and the second captured image C2 is the image of the target particle of FIG. 8 after the target particle of FIG. 4(b) has been cultured for two days. Optionally, when the similarity of the target particles on the first captured image C and the second captured image C2 is equal to or greater than a preset similarity, the operation unit 110 determines the first captured image C2 as the second captured image C2. 2 Comparison between the first calculation information for the first captured image C and the second captured image C2 is performed without calculating calculation information through external data obtained from the external data server D. Second calculation information may be calculated.

That is, the calculation unit 110 compares each target particle of the second captured image C2 with each target particle of the first captured image C for which the first calculation information has already been generated, 2 It is possible to calculate the type and number of target particles on the captured image C2.

Meanwhile, the calculation unit 110 determines whether the first captured image C and the second captured image C2 have a similarity of target particles that is less than a preset similarity, and determines the first captured image C with respect to the first captured image C2. The second calculation information may be calculated using the previously stored external data of the fine particles and the second captured image C2 as in the step of calculating the calculation information described above (S12) without using the calculation information.

On the other hand, the method of analyzing microparticles of cells or microorganisms includes the step (S22) of generating result information (B) by mapping the second calculation information onto the second captured image (C2) by the processing unit 120; The communication unit 200 may further include a step (S23) of transmitting the result information (B) to the portable terminal (P), wherein the step (S22) of generating the result information (B) is the first When the second calculation information for the second captured image C2 is calculated using the first calculation information for the captured image C, the first captured image ( The result information (B) overlapping C) can be generated.

To explain this in more detail, when the second calculation information for the second captured image C2 is calculated using the first calculation information for the first captured image C, that is, the first captured image When the similarity between (C) and the target particle on the second captured image (C2) is greater than or equal to the preset similarity, the processing unit 120 may allow the user to more easily recognize the cultured state and culture change of the particle in the second captured image. The result information (B) obtained by overlapping the first captured image (C) in (C2) may be generated.

9 is an example for explaining the result information (B) displayed on the user's portable terminal (P), using the first calculation information for the first captured image (C) to obtain the second captured image. When the second calculation information for (C2) is calculated, the result information (B) is on the second captured image C2 described with reference to FIG. 8, and the second calculation information described with reference to FIG. 4(b) 1 captured image C may overlap, and furthermore, target particles on the first captured image C may be converted into dotted lines and displayed, and furthermore, the identification icon displaying each target particle and the discrimination icon It may be displayed information.

In particular, the third target particle a3, which is an unknown target particle that is not defined/calculated as a specific species in the first captured image C described with reference to FIG. 5, is cultured to form the second captured image C2. In the image, when the first target particle (a1) is defined/calculated as 'OO species', the discrimination icon is displayed on the target particle (for example, displayed as a green box or a dotted box), and the border thereof The first identification icon may be additionally displayed (eg, displayed as a red box or a box with a dashed-two dotted line), and the number of the first target particles a1 is added by one more information (number information on differences) may also be included.

Similarly, the third target particle a3, which is an unknown target particle that is not defined/calculated as a specific species in the first captured image C, is cultured, and the second target particle a3 in the second captured image C2 If it is defined/calculated as 'ΔΔ species' in (a2), the discrimination icon is displayed on the target particle (for example, displayed as a green box or a dotted box), and the second identification is displayed on the border thereof. An icon may be additionally displayed (for example, displayed as a blue box or a box with a dashed-dot line), and information in which one more number of the second target particles a2 is added (information on the difference in the number) may also be displayed. can be included

As a result, the user can easily recognize the type and number of target particles at the first time point and the type and number of target particles at the second time point, and can also easily recognize a change in target particles due to a change in point of view. can

In the above, the configuration and characteristics of the present invention have been described based on the embodiments according to the present invention, but the present invention is not limited thereto, and various changes or modifications can be made within the spirit and scope of the present invention. It is apparent to those skilled in the art, and therefore such changes or modifications are intended to fall within the scope of the appended claims.

Claims

In the method for analyzing fine particles of cells or microorganisms,

receiving, by a communication unit, a captured image of a target particle from a portable terminal;

Calculating calculation information on the type and number of target particles using the captured image and external data of fine particles stored in advance by a calculation unit;

generating result information by a processing unit by mapping the calculated information onto the photographed image; and

Transmitting the result information to the portable terminal by the communication unit; including,

A method for analyzing microparticles in cells or microorganisms.
According to claim 1,

The result information,

An identification icon displaying the target particle calculated by the calculation unit on the photographed image,

The identification icon,

Displayed differently for each type of target particle,

A method for analyzing microparticles in cells or microorganisms.
According to claim 2,

receiving, by the communication unit, selection information of the identification icon from the portable terminal;

generating, by the processing unit, feedback result information displaying only target particles corresponding to the identification icon selected on the photographed image; and

Transmitting the feedback result information to the portable terminal by the communication unit; further comprising,

A method for analyzing microparticles in cells or microorganisms.
According to claim 2,

The result information is

Including a distinction icon for displaying target particles that the calculation unit could not calculate on the captured image,

A method for analyzing microparticles in cells or microorganisms.
According to claim 4,

receiving, by the communication unit, selection information of the distinction icon from the portable terminal;

calculating a degree of similarity between the target particle calculated by the calculation unit and the target particle that has not been calculated corresponding to the selected distinction icon;

generating, by the processing unit, feedback result information indicating a degree of similarity calculated on the photographed image; and

Transmitting the feedback result information to the portable terminal by the communication unit; further comprising,

A method for analyzing microparticles in cells or microorganisms.
In the cell or microbial fine particle analysis system,

a communication unit for receiving a photographed image of a target particle from a portable terminal;

a calculation unit that calculates calculation information on the type and number of target particles using previously stored external data of fine particles and the captured image; and

A processor configured to generate result information by mapping the calculated information onto the photographed image;

The communication department,

Transmitting the result information to the portable terminal,

A method for analyzing microparticles in cells or microorganisms.