WO2023092807A1 - 带有标识环的冰冻样本托 - Google Patents

带有标识环的冰冻样本托 Download PDF

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Publication number
WO2023092807A1
WO2023092807A1 PCT/CN2021/142616 CN2021142616W WO2023092807A1 WO 2023092807 A1 WO2023092807 A1 WO 2023092807A1 CN 2021142616 W CN2021142616 W CN 2021142616W WO 2023092807 A1 WO2023092807 A1 WO 2023092807A1
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WO
WIPO (PCT)
Prior art keywords
sample holder
frozen sample
identification
identification ring
frozen
Prior art date
Application number
PCT/CN2021/142616
Other languages
English (en)
French (fr)
Inventor
丁伟
施瑜
Original Assignee
丁伟
施瑜
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 丁伟, 施瑜 filed Critical 丁伟
Priority to US17/641,696 priority Critical patent/US20230415159A1/en
Priority to EP21863091.1A priority patent/EP4209772A4/en
Publication of WO2023092807A1 publication Critical patent/WO2023092807A1/zh

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/42—Low-temperature sample treatment, e.g. cryofixation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/54—Labware with identification means
    • B01L3/545—Labware with identification means for laboratory containers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/50—Clamping means, tongs
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
    • G01N1/06—Devices for withdrawing samples in the solid state, e.g. by cutting providing a thin slice, e.g. microtome
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00722—Communications; Identification
    • G01N35/00732—Identification of carriers, materials or components in automatic analysers
    • G—PHYSICS
    • G09—EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
    • G09G—ARRANGEMENTS OR CIRCUITS FOR CONTROL OF INDICATING DEVICES USING STATIC MEANS TO PRESENT VARIABLE INFORMATION
    • G09G3/00—Control arrangements or circuits, of interest only in connection with visual indicators other than cathode-ray tubes
    • G09G3/20—Control arrangements or circuits, of interest only in connection with visual indicators other than cathode-ray tubes for presentation of an assembly of a number of characters, e.g. a page, by composing the assembly by combination of individual elements arranged in a matrix no fixed position being assigned to or needed to be assigned to the individual characters or partial characters
    • G09G3/22—Control arrangements or circuits, of interest only in connection with visual indicators other than cathode-ray tubes for presentation of an assembly of a number of characters, e.g. a page, by composing the assembly by combination of individual elements arranged in a matrix no fixed position being assigned to or needed to be assigned to the individual characters or partial characters using controlled light sources
    • G09G3/30—Control arrangements or circuits, of interest only in connection with visual indicators other than cathode-ray tubes for presentation of an assembly of a number of characters, e.g. a page, by composing the assembly by combination of individual elements arranged in a matrix no fixed position being assigned to or needed to be assigned to the individual characters or partial characters using controlled light sources using electroluminescent panels
    • G09G3/32—Control arrangements or circuits, of interest only in connection with visual indicators other than cathode-ray tubes for presentation of an assembly of a number of characters, e.g. a page, by composing the assembly by combination of individual elements arranged in a matrix no fixed position being assigned to or needed to be assigned to the individual characters or partial characters using controlled light sources using electroluminescent panels semiconductive, e.g. using light-emitting diodes [LED]
    • G—PHYSICS
    • G09—EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
    • G09G—ARRANGEMENTS OR CIRCUITS FOR CONTROL OF INDICATING DEVICES USING STATIC MEANS TO PRESENT VARIABLE INFORMATION
    • G09G3/00—Control arrangements or circuits, of interest only in connection with visual indicators other than cathode-ray tubes
    • G09G3/20—Control arrangements or circuits, of interest only in connection with visual indicators other than cathode-ray tubes for presentation of an assembly of a number of characters, e.g. a page, by composing the assembly by combination of individual elements arranged in a matrix no fixed position being assigned to or needed to be assigned to the individual characters or partial characters
    • G09G3/22—Control arrangements or circuits, of interest only in connection with visual indicators other than cathode-ray tubes for presentation of an assembly of a number of characters, e.g. a page, by composing the assembly by combination of individual elements arranged in a matrix no fixed position being assigned to or needed to be assigned to the individual characters or partial characters using controlled light sources
    • G09G3/30—Control arrangements or circuits, of interest only in connection with visual indicators other than cathode-ray tubes for presentation of an assembly of a number of characters, e.g. a page, by composing the assembly by combination of individual elements arranged in a matrix no fixed position being assigned to or needed to be assigned to the individual characters or partial characters using controlled light sources using electroluminescent panels
    • G09G3/32—Control arrangements or circuits, of interest only in connection with visual indicators other than cathode-ray tubes for presentation of an assembly of a number of characters, e.g. a page, by composing the assembly by combination of individual elements arranged in a matrix no fixed position being assigned to or needed to be assigned to the individual characters or partial characters using controlled light sources using electroluminescent panels semiconductive, e.g. using light-emitting diodes [LED]
    • G09G3/3208—Control arrangements or circuits, of interest only in connection with visual indicators other than cathode-ray tubes for presentation of an assembly of a number of characters, e.g. a page, by composing the assembly by combination of individual elements arranged in a matrix no fixed position being assigned to or needed to be assigned to the individual characters or partial characters using controlled light sources using electroluminescent panels semiconductive, e.g. using light-emitting diodes [LED] organic, e.g. using organic light-emitting diodes [OLED]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/02—Identification, exchange or storage of information
    • B01L2300/021—Identification, e.g. bar codes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0803—Disc shape
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1894—Cooling means; Cryo cooling
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
    • G01N2001/2873—Cutting or cleaving
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00722—Communications; Identification
    • G01N35/00732—Identification of carriers, materials or components in automatic analysers
    • G01N2035/00792—Type of components bearing the codes, other than sample carriers
    • G01N2035/00801—Holders for sample carriers, e.g. trays, caroussel, racks
    • G—PHYSICS
    • G09—EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
    • G09G—ARRANGEMENTS OR CIRCUITS FOR CONTROL OF INDICATING DEVICES USING STATIC MEANS TO PRESENT VARIABLE INFORMATION
    • G09G2300/00—Aspects of the constitution of display devices
    • G09G2300/04—Structural and physical details of display devices
    • G09G2300/0439—Pixel structures
    • G09G2300/0443—Pixel structures with several sub-pixels for the same colour in a pixel, not specifically used to display gradations
    • G—PHYSICS
    • G09—EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
    • G09G—ARRANGEMENTS OR CIRCUITS FOR CONTROL OF INDICATING DEVICES USING STATIC MEANS TO PRESENT VARIABLE INFORMATION
    • G09G2330/00—Aspects of power supply; Aspects of display protection and defect management
    • G09G2330/04—Display protection

Definitions

  • the present application relates to the technical field of frozen section related equipment, in particular to a frozen sample holder with an identification ring.
  • Frozen section is the most widely used method in routine histological preparation techniques. Frozen section is not only used to observe the morphological structure of normal cell tissue, but also the main method used in clinical, scientific research pathology and forensic science to study, observe and judge the morphological changes of cell tissue, and has been widely used in many other disciplines research in the field.
  • the present application provides a frozen sample holder with an identification ring, which at least solves the technical problem in the related art that the frozen sample holder is difficult to identify and cause multiple samples to be confused.
  • the application provides a frozen sample holder with an identification ring, which may include an identification ring structure and a frozen sample holder structure, and the identification ring structure is connected to the outer wall of the frozen sample holder structure;
  • the identification ring structure includes an identification part, and the identification part is used to identify the information of the sample in the frozen sample holder structure.
  • the identification ring structure may include an identification ring body and an identification plate, and the identification ring body is connected to the identification plate;
  • the identification ring body is provided with an accommodating space, and the frozen sample holder structure can be at least partially accommodated in the accommodating space and connected with the identification ring body;
  • the identification part may be provided on the same side of the identification plate as the surface on which the frozen sample holder structure is placed.
  • the identification ring body and the identification plate are integrally formed, the identification ring body can be a ring structure, and the area surrounded by the inner ring wall of the identification ring body can be set as an accommodating space, so
  • the accommodating space may be a cylindrical space, the frozen sample holder structure may be arranged in the accommodating space and fixed relative to the identification ring body; the identification plate may be connected to the outer wall of the identification ring body, The identification part provided on the upper surface of the identification plate can be used to mark the two-dimensional code and the pathological number of the sample in the frozen sample holder structure.
  • the identification ring structure may also include a block, the block may be connected to the identification ring body, and the block may be located in the accommodating space;
  • the frozen sample holder structure may include a frozen sample holder body and a card slot;
  • the clamping slot can be arranged along the circumferential direction of the frozen sample holder body, and the clamping block can be clamped in the clamping slot for connecting the frozen sample holder body with the identification ring body.
  • the clamping block can be arranged on the inner ring wall of the identification ring body, and the clamping block can be clamped in the clamping groove on the edge of the frozen sample holder body, providing the frozen sample holder
  • the body provides a vertical support; the outer edge of the frozen sample holder body abuts against the inner edge of the identification ring body.
  • the identification ring structure may also include a raised portion, the raised portion may be arranged along the inner ring wall of the identification ring body in the circumferential direction, and the raised portion may be connected to the top surface of the frozen sample holder body. offset, and the raised portion is located above the block.
  • the raised portion can be arranged along the top circumference of the inner ring wall of the identification ring body to form an annular limit baffle, when the identification ring body is set on the frozen sample holder body The top surface of the frozen sample holder body abuts against the bottom surface of the protrusion; and the surrounding structure formed between the protrusion and the identification ring body is at the edge of the top surface of the frozen sample holder body.
  • At least one clamping block may be provided, and when multiple clamping blocks are provided, the multiple clamping blocks are evenly distributed along the circumference of the accommodating space.
  • the frozen sample holder body may include a groove body and a boss, and the groove body and the boss may be arranged coaxially;
  • grooves and bosses There may be multiple grooves and bosses, and multiple grooves and bosses may be alternately surrounded from outside to inside.
  • the bosses may be ring-shaped, and the distances between adjacent bosses are the same, the grooves may be arranged between adjacent bosses, and the grooves may be circular.
  • the bottom surface of the tank may be inclined toward the center along the edge of the frozen sample holder body.
  • the bottom of the frozen sample holder body can pass through the lower end of the identification ring body.
  • the inner and outer edges of the identification ring body on the side away from the placement surface of the frozen sample holder structure may be chamfered.
  • the inner and outer edges of the lower end of the identification ring body may be provided with a certain radian, so that the frozen sample holder body may not be in contact with the lower end of the identification ring body, leaving a certain gap.
  • the upper surface of the identification plate may be inclined downward toward the side away from the placement surface of the frozen sample holder structure.
  • the application provides a frozen sample holder with an identification ring, including an identification ring structure and a frozen sample holder structure, the identification ring structure is connected to the outer wall of the frozen sample holder structure; the identification ring structure includes an identification part, the The identification part is used to identify the information of the sample in the frozen sample holder structure.
  • the present application solves the technical problem of multiple samples confusion caused by the difficulty in identifying frozen sample holders in the related art.
  • FIG. 1 is a schematic top view of a frozen sample holder with an identification ring provided in Embodiment 1 of the present application;
  • Fig. 2 is the bottom view structural representation of the identification ring structure of the frozen sample holder with identification ring shown in Fig. 1;
  • Fig. 3 is the side view structure schematic diagram of the frozen sample holder structure of the frozen sample holder with identification ring shown in Fig. 1;
  • Fig. 4 is the side view structural representation of the frozen sample holder with identification ring shown in Fig. 1;
  • FIG. 5 is a schematic top view of the frozen sample holder provided in Embodiment 2 of the present application with an identification ring.
  • Icons 1-identification ring structure; 11-identification ring body; 12-identification plate; 13-block; 14-protrusion; 2-frozen sample holder structure; 21-frozen sample holder body; -boss; 22-card slot.
  • orientation or positional relationship indicated by the terms “upper”, “lower”, “vertical”, “horizontal”, “inner”, “outer” and so on are based on the Orientation or positional relationship, or the orientation or positional relationship that the invention product is usually placed in use, is only for the convenience of describing the application and simplifying the description, rather than indicating or implying that the referred device or element must have a specific orientation, constructed and operated in a particular orientation and therefore should not be construed as limiting the application.
  • the terms “first”, “second”, “third”, etc. are only used for distinguishing descriptions, and should not be construed as indicating or implying relative importance.
  • horizontal does not imply that a component is absolutely level or overhanging, but may be slightly inclined.
  • horizontal only means that its direction is more horizontal than “vertical”, and it does not mean that the structure must be completely horizontal, but can be slightly inclined.
  • the frozen sample holder with an identification ring includes an identification ring structure 1 and a frozen sample holder structure 2.
  • the identification ring structure 1 is connected to the outer wall of the frozen sample holder structure 2; the identification ring structure 1 includes an identification part, and the identification part is used to identify the information of the sample in the frozen sample holder structure 2.
  • the frozen sample holder with the identification ring provided by the embodiment of the present application at least alleviates the technical problem in the related art that the frozen sample holder is difficult to identify and cause multiple samples to be confused.
  • Some embodiments of the present application provide a frozen sample holder with an identification ring, including an identification ring structure 1 and a frozen sample holder structure 2, the identification ring structure 1 is connected to the outer wall of the frozen sample holder structure 2; the identification The ring structure 1 includes an identification part, and the identification part is used to identify the information of the sample in the frozen sample holder structure 2 .
  • the identification ring structure 1 is placed outside the frozen sample holder structure 2, and the specific information of the sample is marked on the identification ring structure 1, without hindering the normal use of the frozen sample holder.
  • the marking of different samples effectively avoids the technical problem of sample confusion caused by difficult identification of frozen sample trays.
  • the identification ring structure 1 includes an identification ring body 11 and an identification plate 12, and the identification ring body 11 is connected to the identification plate 12; the identification ring body 11 is provided with an accommodating space for freezing samples
  • the holder structure 2 is at least partially accommodated in the accommodating space and connected with the identification ring body 11; the identification plate 12 is provided with an identification part on the same side as the frozen sample holder structure 2 placement surface.
  • the identification ring body 11 and the identification plate 12 are integrally formed, the identification ring body 11 is a ring structure, and the area surrounded by its inner ring wall is set as an accommodation space, this accommodation space is a cylindrical space, and the frozen sample holder
  • the structure 2 is arranged in this accommodating space, and is fixed relative to the identification ring body 11; the identification plate 12 is connected to the outer wall of the identification ring body 11, and the identification part provided on the upper surface of the identification plate 12 is used to identify the frozen sample holder structure 2.
  • the two-dimensional code of the sample and the pathology number are marked.
  • the identification ring structure 1 also includes a block 13, which is connected to the identification ring body 11, and the block 13 is located in the accommodating space;
  • the frozen sample holder structure 2 includes a frozen sample holder body 21 and Card slot 22 ;
  • the card slot 22 is arranged along the circumferential direction of the frozen sample holder body 21 , and the clamp block 13 is snapped into the card slot 22 for connecting the frozen sample holder body 21 with the identification ring body 11 .
  • the inner ring wall of the identification ring body 11 is provided with a clamping block 13, and the clamping block 13 is clamped in the slot 22 on the edge of the frozen sample holder body 21 to provide a vertical support for the frozen sample holder body 21; and The outer edge of the frozen sample holder body 21 abuts against the inner edge of the identification ring body 11 .
  • the identification ring structure 1 also includes a raised portion 14, which is arranged circumferentially along the inner ring wall of the identification ring body 11, the raised portion 14 abuts against the top surface of the frozen sample holder body 21, and the raised portion 14 Located above the block 13.
  • the raised portion 14 is arranged along the top circumferential direction of the inner ring wall of the marking ring body 11 to form an annular limit baffle.
  • the marking ring body 11 When the marking ring body 11 is set on the frozen sample holder body 21, the frozen sample holder body 21 The top surface is against the bottom surface of the raised portion 14, which effectively prevents the frozen sample holder body 21 from protruding from the top of the identification ring body 11;
  • the enclosing structure prevents damage to the edge of the top surface of the frozen sample holder body 21 due to bumping.
  • At least one locking block 13 is provided.
  • the plurality of locking blocks 13 are evenly distributed along the circumference of the accommodating space.
  • a plurality of clamping blocks 13 are evenly distributed on the inner ring wall of the identification ring body 11, and the clamping blocks 13 are clamped in the slot 22 on the edge of the frozen sample holder body 21 to provide a vertical direction for the frozen sample holder body 21 support, and maintain the balance of the frozen sample holder body 21.
  • the frozen sample holder body 21 includes a groove 211 and a boss 212, and the groove 211 and the boss 212 are coaxially arranged; there are multiple grooves 211 and the boss 212, and there are multiple The groove body 211 and the plurality of bosses 212 are alternately surrounded from outside to inside.
  • the top surface of the frozen sample holder body 21 is alternately surrounded by a plurality of grooves 211 and a plurality of bosses 212 from the outside to the inside, the bosses 212 are ring-shaped structures, and the distance between adjacent bosses 212 is the same , the groove body 211 is disposed between adjacent bosses 212, so it can be seen that the groove body 211 is also annular.
  • the operator places the sample slices on the top surface of the frozen sample holder body 21, and the multiple grooves 211 and the multiple bosses 212 on the top surface of the frozen sample holder body 21 form a rough surface, which effectively prevents the sample slices from freezing.
  • the top surface of the sample holder body 21 slides.
  • the bottom surface of the tank body 211 is inclined toward the center along the edge of the frozen sample holder body 21 .
  • a plurality of grooves 211 are arranged between adjacent bosses 212 one by one, and the bottom surface of the grooves 211 is inclined toward the center along the edge of the frozen sample holder body 21 , which helps the samples to gather toward the center of the top surface of the frozen sample holder body 21 .
  • the bottom of the frozen sample holder body 21 passes through the lower end of the identification ring body 11 . After the frozen sample holder body 21 is placed on the machine, the bottom surface of the frozen sample holder body 21 is in contact with the machine, which avoids the problem of the frozen sample holder body 21 being tilted after being placed.
  • the inner and outer edges of the identification ring body 11 on the side away from the placement surface of the frozen sample holder structure 2 are chamfered.
  • the inner and outer edges of the lower end of the identification ring body 11 are provided with a certain radian, so that the frozen sample holder body 21 does not contact the lower end of the identification ring body 11, and a certain gap is reserved; during the process of installing the whole device on the machine, it becomes more The convenience, will not collide with the machine.
  • the upper surface of the identification plate 12 slopes downward toward the side away from the placement surface of the frozen sample holder structure 2 .
  • the identification part on the upper surface of the identification plate 12 can face the operator at an angle that is easier to observe after the frozen sample holder body 21 is placed, which is convenient for the operator to identify, scan codes and record.
  • FIG. Symmetrical polygonal structure This structure helps to improve the balance and stability of the identification ring structure 1 and the frozen sample holder structure 2 after the frozen sample holder structure 2 is placed.
  • each embodiment in this specification is described in a progressive manner, each embodiment focuses on the differences from other embodiments, and the same and similar parts of each embodiment refer to each other That is to say; the above embodiments in this description are only used to illustrate the technical solutions of the present application, not to limit it; although the application has been described in detail with reference to the foregoing embodiments, those of ordinary skill in the art should understand that: It can still modify the technical solutions described in the foregoing embodiments, or perform equivalent replacements for some or all of the technical features; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the technical solutions of the various embodiments of the application. range.
  • the application provides a frozen sample holder with an identification ring, including an identification ring structure and a frozen sample holder structure, the identification ring structure is connected to the outer wall of the frozen sample holder structure; the identification ring structure includes an identification part, and the identification part is used to identify the frozen sample holder Information about samples within the structure.
  • the present application alleviates the technical problem of the confusion of multiple samples caused by the difficulty in identifying the frozen sample holder in the frozen section operation process.
  • the frozen sample holder with identification ring of the present application is reproducible and can be used in various industrial applications.
  • the frozen sample holder with the identification ring of the present application can be used in technical fields related to frozen section related equipment.

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Computer Hardware Design (AREA)
  • Theoretical Computer Science (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

一种带有标识环的冰冻样本托，涉及冰冻切片相关设备的技术领域，包括标识环结构（1）和冰冻样本托结构（2），标识环结构（1）与冰冻样本托结构（2）外壁连接；标识环结构（1）包括标识部，标识部用于标识冰冻样本托结构内样本的信息；缓解了一直以来冰冻切片操作过程中存在的冰冻样本托难以标识而造成的多个样本混淆的技术问题。

Description

带有标识环的冰冻样本托
相关申请的交叉引用
本申请要求于2021年11月25日提交中国国家知识产权局的申请号为202111411326.X、名称为“带有标识环的冰冻样本托”的中国专利申请的优先权，其全部内容通过引用结合在本申请中。
技术领域
本申请涉及冰冻切片相关设备的技术领域，尤其是涉及一种带有标识环的冰冻样本托。
背景技术
冰冻切片是组织学常规制片技术中最为广泛应用的方法。冰冻切片不仅用于观察正常细胞组织的形态结构，也是临床、科研病理学和法医学等学科用以研究、观察及判断细胞组织的形态变化的主要方法，而且也已相当广泛地用于其他许多学科领域的研究中。
病理组织冰冻切片过程中，对于冰冻切片机内的冰冻样本托的标记，一直以来都是难点，虽然可以通过纸张打印粘贴方式实现，但冷冻后纸张容易脱落、被刀切坏等意外，导致样本混淆造成医疗事故。
发明内容
本申请提供了一种带有标识环的冰冻样本托，从而至少解决了相关技术中存在的冰冻样本托难以标识而造成的多个样本混淆的技术问题。
本申请提供了一种带有标识环的冰冻样本托，可以包括标识环结构和冰冻样本托结构，所述标识环结构与所述冰冻样本托结构外壁连接；
所述标识环结构包括标识部，所述标识部用于标识所述冰冻样本托结构内样本的信息。
本申请可选的实施方式中，所述标识环结构可以包括标识环本体和标识板，所述标识环本体与所述标识板连接；
所述标识环本体设有容置空间，所述冰冻样本托结构可以至少部分容置于所述容置空间并与所述标识环本体连接；
所述标识板相对于所述冰冻样本托结构放置面的同侧面上可以设有所述标识部。
可选地，所述标识环本体和所述标识板一体成型，所述标识环本体可以为环状结构，且所述标识环本体的内环壁围成的区域可以设置为容置空间，所述容置空间可以为圆柱体空间，所述冰冻样本托结构可以设置在所述容置空间内并相对于所述标识环本体固定；所述标识板可以与所述标识环本体外侧壁连接，所述标识板的上表面设置的所述标识部可以用于对所述冰冻样本托结构中的样本的二维码以及病理号进行标记。
可选地，所述标识环结构还可以包括卡块，所述卡块可以与所述标识环本体连接，且 所述卡块可以位于所述容置空间内；
所述冰冻样本托结构可以包括冰冻样本托本体和卡槽；
所述卡槽可以沿所述冰冻样本托本体周向设置，所述卡块可以卡接于所述卡槽内，用于将所述冰冻样本托本体与所述标识环本体连接。
可选地，所述卡块可以设置在所述标识环本体的内环壁上，所述卡块可以卡接在所述冰冻样本托本体边缘的所述卡槽内，为所述冰冻样本托本体提供一个竖直方向的支撑；所述冰冻样本托本体外边缘与所述标识环本体内边缘抵接。
可选地，所述标识环结构还可以包括凸起部，所述凸起部可以沿所述标识环本体内环壁周向设置，所述凸起部可以与所述冰冻样本托本体顶面相抵，且所述凸起部位于所述卡块的上方。
可选地，所述凸起部可以沿所述标识环本体内环壁的顶部周向设置，形成一环形限位挡板，当将所述标识环本体套装在所述冰冻样本托本体上时，所述冰冻样本托本体顶面抵在所述凸起部底面；且所述凸起部与所述标识环本体之间在所述冰冻样本托本体顶面边缘处形成的包围结构。
本申请可选的实施方式中，所述卡块可以至少设有一个，当所述卡块设为多个时，多个所述卡块沿所述容置空间周向均匀分布。
本申请可选的实施方式中，所述冰冻样本托本体可以包括槽体和凸台，所述槽体和所述凸台可以同轴设置；
所述槽体和所述凸台可以均有多个，且多个所述槽体和多个所述凸台可以由外至内交替围设。
可选地，所述凸台可以为环状结构，且相邻的所述凸台之间的间隔距离相同，所述槽体可以设置在相邻的凸台之间，所述槽体可以是环形的。
可选地，所述槽体底面可以沿所述冰冻样本托本体边缘向中心方向倾斜。
本申请可选的实施方式中，所述冰冻样本托本体底部可以从所述标识环本体下端穿出。
本申请可选的实施方式中，所述标识环本体远离所述冰冻样本托结构放置面的一面的内外边缘可以倒角。
可选地，所述标识环本体下端内外侧边缘可以设置一定的弧度，使得所述冰冻样本托本体可以不与所述标识环本体下端接触，保留一定的空隙。
本申请可选的实施方式中，所述标识板上表面朝向远离所述冰冻样本托结构放置面的一侧可以向下倾斜。
本申请的实施例能够实现至少如下有益效果：
本申请提供一种带有标识环的冰冻样本托，包括标识环结构和冰冻样本托结构，所述 标识环结构与所述冰冻样本托结构外壁连接；所述标识环结构包括标识部，所述标识部用于标识所述冰冻样本托结构内样本的信息。
在本申请中，通过在冰冻样本托结构外部套装标识环结构，并在标识环结构上标识出样本的具体信息，在不妨碍冰冻样本托正常使用的前提下，实现对不同样本的标记，有效避免了冰冻样本托难以标识而造成样本混淆的技术问题。
综上，本申请解决了相关技术中存在的冰冻样本托难以标识而造成的多个样本混淆的技术问题。
附图说明
为了更清楚地说明本申请具体实施方式或相关技术中的技术方案，下面将对具体实施方式或相关技术描述中所需要使用的附图作简单地介绍，显而易见地，下面描述中的附图是本申请的一些实施方式，对于本领域普通技术人员来讲，在不付出创造性劳动的前提下，还可以根据这些附图获得其他的附图。
图1为本申请实施例一提供的带有标识环的冰冻样本托的俯视结构示意图；
图2为图1中示出的带有标识环的冰冻样本托的标识环结构的仰视结构示意图；
图3为图1中示出的带有标识环的冰冻样本托的冰冻样本托结构的侧视结构示意图；
图4为图1中示出的带有标识环的冰冻样本托的侧视结构示意图；
图5为本申请实施例二提供的带有标识环的冰冻样本托的俯视结构示意图。
图标：1-标识环结构；11-标识环本体；12-标识板；13-卡块；14-凸起部；2-冰冻样本托结构；21-冰冻样本托本体；211-槽体；212-凸台；22-卡槽。
具体实施方式
为使本申请实施例的目的、技术方案和优点更加清楚，下面将结合本申请实施例中的附图，对本申请实施例中的技术方案进行清楚、完整地描述，显然，所描述的实施例是本申请一部分实施例，而不是全部的实施例。通常在此处附图中描述和示出的本申请实施例的组件可以各种不同的配置来布置和设计。
因此，以下对在附图中提供的本申请的实施例的详细描述并非旨在限制要求保护的本申请的范围，而是仅仅表示本申请的选定实施例。基于本申请中的实施例，本领域普通技术人员在没有作出创造性劳动前提下所获得的所有其他实施例，都属于本申请保护的范围。
应注意到：相似的标号和字母在下面的附图中表示类似项，因此，一旦某一项在一个附图中被定义，则在随后的附图中不需要对其进行进一步定义和解释。
在本申请的描述中，需要说明的是，术语“上”、“下”、“竖直”、“水平”、“内”、“外”等指示的方位或位置关系为基于附图所示的方位或位置关系，或者是该发明产品使用时惯常摆放的方位或位置关系，仅是为了便于描述本申请和简化描述，而不是指示或暗示所指的 装置或元件必须具有特定的方位、以特定的方位构造和操作，因此不能理解为对本申请的限制。此外，术语“第一”、“第二”、“第三”等仅用于区分描述，而不能理解为指示或暗示相对重要性。
此外，术语“水平”、“竖直”等术语并不表示要求部件绝对水平或悬垂，而是可以稍微倾斜。如“水平”仅仅是指其方向相对“竖直”而言更加水平，并不是表示该结构一定要完全水平，而是可以稍微倾斜。
在本申请的描述中，还需要说明的是，除非另有明确的规定和限定，术语“设置”、“安装”、“连接”应做广义理解，例如，可以是固定连接，也可以是可拆卸连接，或一体地连接；可以是机械连接，也可以是电连接；可以是直接相连，也可以通过中间媒介间接相连，可以是两个元件内部的连通。对于本领域的普通技术人员而言，可以具体情况理解上述术语在本申请中的具体含义。
下面结合附图，对本申请的一些实施方式作详细说明。在不冲突的情况下，下述的实施例及实施例中的特征可以相互组合。
本申请的一些实施例提供了一种带有标识环的冰冻样本托，参照图1和图3，该带有标识环的冰冻样本托包括标识环结构1和冰冻样本托结构2，标识环结构1与冰冻样本托结构2外壁连接；标识环结构1包括标识部，标识部用于标识冰冻样本托结构2内样本的信息。
本申请的实施例所提供的带有标识环的冰冻样本托至少缓解了相关技术中存在的冰冻样本托因难以标识而造成的多个样本混淆的技术问题。
本申请的一些实施例提供一种带有标识环的冰冻样本托，包括标识环结构1和冰冻样本托结构2，所述标识环结构1与所述冰冻样本托结构2外壁连接；所述标识环结构1包括标识部，所述标识部用于标识所述冰冻样本托结构2内样本的信息。
在本申请的一些实施例中，通过在冰冻样本托结构2外部套装标识环结构1，并在标识环结构1上标识出样本的具体信息，在不妨碍冰冻样本托正常使用的前提下，实现对不同样本的标记，有效避免了冰冻样本托出现因难以标识而造成样本混淆的技术问题。
本实施例可选的实施方式中，参照图2，标识环结构1包括标识环本体11和标识板12，标识环本体11与标识板12连接；标识环本体11设有容置空间，冰冻样本托结构2至少部分容置于容置空间并与标识环本体11连接；标识板12相对于冰冻样本托结构2放置面的同侧面上设有标识部。
具体的：标识环本体11和标识板12一体成型，标识环本体11为环状结构，且其内环壁围成的区域设置为容置空间，此容置空间为圆柱体空间，冰冻样本托结构2设置在此容置空间内，并相对于标识环本体11固定；标识板12与标识环本体11外侧壁连接，标识板 12的上表面设置的标识部用于对冰冻样本托结构2中的样本的二维码以及病理号等进行标记。
可选地，参照图2，标识环结构1还包括卡块13，卡块13与标识环本体11连接，且卡块13位于容置空间内；冰冻样本托结构2包括冰冻样本托本体21和卡槽22；卡槽22沿冰冻样本托本体21周向设置，卡块13卡接于卡槽22内，用于将冰冻样本托本体21与标识环本体11连接。
具体的：标识环本体11的内环壁上设置卡块13，卡块13卡接在冰冻样本托本体21边缘的卡槽22内，为冰冻样本托本体21提供一个竖直方向的支撑；而冰冻样本托本体21外边缘则与标识环本体11内边缘抵接。
可选地，标识环结构1还包括凸起部14，凸起部14沿标识环本体11内环壁周向设置，凸起部14与冰冻样本托本体21顶面相抵，且凸起部14位于卡块13的上方。
具体的：凸起部14沿标识环本体11内环壁的顶部周向设置，形成一环形限位挡板，当将标识环本体11套装在冰冻样本托本体21上时，冰冻样本托本体21顶面抵在凸起部14底面，有效避免了冰冻样本托本体21从标识环本体11顶部顶出；且凸起部14与标识环本体11之间在冰冻样本托本体21顶面边缘处形成的包围结构，避免冰冻样本托本体21顶面边缘因磕碰造成损坏。
本实施例可选的实施方式中，卡块13至少设有一个，当卡块13设为多个时，多个卡块13沿所述容置空间周向均匀分布。
具体的：多个卡块13均匀分布于标识环本体11的内环壁上，卡块13卡接在冰冻样本托本体21边缘的卡槽22内，为冰冻样本托本体21提供一个竖直方向的支撑，并维持冰冻样本托本体21的平衡。
本实施例可选的实施方式中，冰冻样本托本体21包括槽体211和凸台212，槽体211和凸台212同轴设置；槽体211和凸台212均有多个，且多个槽体211和多个凸台212由外至内交替围设。
具体的，冰冻样本托本体21顶面由外至内交替围设多个槽体211和多个凸台212，凸台212为环状结构，且相邻的凸台212之间的间隔距离相同，槽体211设置在相邻的凸台212之间，因此可知槽体211也为环形。
在使用过程中，操作人员将样本切片放置在冰冻样本托本体21顶面，而冰冻样本托本体21顶面的多个槽体211和多个凸台212形成粗糙表面，有效避免样本切片在冰冻样本托本体21顶面滑动。
可选地，槽体211底面沿冰冻样本托本体21边缘向中心方向倾斜。多个槽体211逐一设置在相邻的凸台212之间，且槽体211底面沿冰冻样本托本体21边缘向中心方向倾斜， 有助于样本向冰冻样本托本体21顶面中心聚拢。
本实施例可选的实施方式中，参照图4，冰冻样本托本体21底部从标识环本体11下端穿出。冰冻样本托本体21放置在机器上后，冰冻样本托本体21底面与机器接触，避免了冰冻样本托本体21在放置后发生倾斜的问题。
本实施例可选的实施方式中，标识环本体11远离冰冻样本托结构2放置面的一面的内外边缘倒角。
具体的：标识环本体11下端内外侧边缘设置一定的弧度，使得冰冻样本托本体21不与标识环本体11下端接触，保留一定的空隙；在将整个装置安装在机器的过程中，变得更加的方便，不会与机器发生碰撞。
本实施例可选的实施方式中，标识板12上表面朝向远离冰冻样本托结构2放置面的一侧向下倾斜。标识板12上表面的标识部则可在冰冻样本托本体21放置好后，可以以一个更便于观察的角度朝向操作人员，便于操作人员辨识、扫码以及记录等。
本申请的另一些实施例提供了一种带有标识环的冰冻样本托，参照图5，该带有标识环的冰冻样本托的标识环本体11和标识板12一体成型，且二者为左右对称的多边形结构。此结构有助于提高冰冻样本托结构2放置后，标识环结构1和冰冻样本托结构2的平衡性和稳定性。
最后应说明的是：本说明书中的各个实施例均采用递进的方式描述，每个实施例重点说明的都是与其它实施例的不同之处，各个实施例之间相同相似的部分相互参见即可；本说明书中的以上各实施例仅用以说明本申请的技术方案，而非对其限制；尽管参照前述各实施例对本申请进行了详细的说明，本领域的普通技术人员应当理解：其依然可以对前述各实施例所记载的技术方案进行修改，或者对其中部分或者全部技术特征进行等同替换；而这些修改或者替换，并不使相应技术方案的本质脱离本申请各实施例技术方案的范围。
工业实用性
本申请提供一种带有标识环的冰冻样本托，包括标识环结构和冰冻样本托结构，标识环结构与冰冻样本托结构外壁连接；标识环结构包括标识部，标识部用于标识冰冻样本托结构内样本的信息。本申请缓解了一直以来冰冻切片操作过程中存在的冰冻样本托难以标识而造成的多个样本混淆的技术问题。
此外，可以理解的是，本申请的带有标识环的冰冻样本托是可以重现的，并且可以用在多种工业应用中。例如，本申请的带有标识环的冰冻样本托可以用于涉及冰冻切片相关设备的技术领域。

Claims (15)

  1. 一种带有标识环的冰冻样本托，其特征在于，包括标识环结构(1)和冰冻样本托结构(2)，所述标识环结构(1)与所述冰冻样本托结构(2)外壁连接；
    所述标识环结构(1)包括标识部，所述标识部用于标识所述冰冻样本托结构(2)内样本的信息。
  2. 根据权利要求1所述的带有标识环的冰冻样本托，其特征在于，所述标识环结构(1)包括标识环本体(11)和标识板(12)，所述标识环本体(11)与所述标识板(12)连接；
    所述标识环本体(11)设有容置空间，所述冰冻样本托结构(2)至少部分容置于所述容置空间并与所述标识环本体(11)连接；
    所述标识板(12)相对于所述冰冻样本托结构(2)放置面的同侧面上设有所述标识部。
  3. 根据权利要求2所述的带有标识环的冰冻样本托，其特征在于，所述标识环本体(11)和所述标识板(12)一体成型，所述标识环本体(11)为环状结构，且所述标识环本体(11)的内环壁围成的区域设置为容置空间，所述容置空间为圆柱体空间，所述冰冻样本托结构(2)设置在所述容置空间内并相对于所述标识环本体(11)固定；
    所述标识板(12)与所述标识环本体(11)外侧壁连接，所述标识部设置在所述标识板(12)的上表面，以用于对所述冰冻样本托结构(2)中的样本的二维码以及病理号进行标记。
  4. 根据权利要求2或3所述的带有标识环的冰冻样本托，其特征在于，所述标识环结构(1)还包括卡块(13)，所述卡块(13)与所述标识环本体(11)连接，且所述卡块(13)位于所述容置空间内；
    所述冰冻样本托结构(2)包括冰冻样本托本体(21)和卡槽(22)；
    所述卡槽(22)沿所述冰冻样本托本体(21)周向设置，所述卡块(13)卡接于所述卡槽(22)内，用于将所述冰冻样本托本体(21)与所述标识环本体(11)连接。
  5. 根据权利要求4所述的带有标识环的冰冻样本托，其特征在于，所述卡块(13)设置在所述标识环本体(11)的内环壁上，所述卡块(13)卡接在所述冰冻样本托本体(21)边缘的所述卡槽(22)内，从而为所述冰冻样本托本体(21)提供一个竖直方向的支撑；所述冰冻样本托本体(21)外边缘与所述标识环本体(11)内边缘抵接。
  6. 根据权利要求4或5所述的带有标识环的冰冻样本托，其特征在于，所述标识环结构(1)还包括凸起部(14)，所述凸起部(14)沿所述标识环本体(11)内环壁周向设置，所述凸起部(14)与所述冰冻样本托本体(21)顶面相抵，且所述凸起部(14)位于所述卡块(13)的上方。
  7. 根据权利要求6所述的带有标识环的冰冻样本托，其特征在于，所述凸起部(14)沿所述标识环本体(11)内环壁的顶部周向设置，形成一环形限位挡板，当将所述标识环本体(11)套装在所述冰冻样本托本体(21)上时，所述冰冻样本托本体(21)顶面抵在所述凸起部(14)底面；且所述凸起部(14)与所述标识环本体(11)之间在所述冰冻样本托本体(21)顶面边缘处形成包围结构。
  8. 根据权利要求4至7中的任一项所述的带有标识环的冰冻样本托，其特征在于，所述卡块(13)至少设有一个，当所述卡块(13)设为多个时，多个所述卡块(13)沿所述容置空间周向均匀分布。
  9. 根据权利要求4至8中的任一项所述的带有标识环的冰冻样本托，其特征在于，所述冰冻样本托本体(21)包括槽体(211)和凸台(212)，所述槽体(211)和所述凸台(212)同轴设置；
    所述槽体(211)和所述凸台(212)均有多个，且多个所述槽体(211)和多个所述凸台(212)由外至内交替围设。
  10. 根据权利要求9所述的带有标识环的冰冻样本托，其特征在于，所述凸台(212)为环状结构，且相邻的所述凸台(212)之间的间隔距离相同，所述槽体(211)设置在相邻的凸台(212)之间，所述槽体(211)是环形的。
  11. 根据权利要求9或10所述的带有标识环的冰冻样本托，其特征在于，所述槽体(211)底面沿所述冰冻样本托本体(21)边缘向中心方向倾斜。
  12. 根据权利要求9至11中的任一项所述的带有标识环的冰冻样本托，其特征在于，所述冰冻样本托本体(21)底部从所述标识环本体(11)下端穿出。
  13. 根据权利要求2至12中的任一项所述的带有标识环的冰冻样本托，其特征在于，所述标识环本体(11)远离所述冰冻样本托结构(2)放置面的一面的内外边缘倒角。
  14. 根据权利要求13所述的带有标识环的冰冻样本托，其特征在于，所述标识环本体(11)下端内外侧边缘设置一定的弧度，使得所述冰冻样本托本体(21)不与所述标识环本体(11)下端接触，保留一定的空隙。
  15. 根据权利要求2至14中的任一项所述的带有标识环的冰冻样本托，其特征在于，所述标识板(12)上表面朝向远离所述冰冻样本托结构(2)放置面的一侧向下倾斜。
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