WO2023079240A1

WO2023079240A1 - Packaged item having documents arranged in an envelope

Info

Publication number: WO2023079240A1
Application number: PCT/FR2022/052064
Authority: WO
Inventors: Didier VILLIERE
Original assignee: Imprimerie Villiere
Priority date: 2021-11-03
Filing date: 2022-11-02
Publication date: 2023-05-11
Also published as: EP4426618A1; FR3128698A1

Abstract

The packaged item (100) comprises an envelope (101) having first and second opposite edges (102, 103), the first edge (102) having a first opening giving access to the inside of the envelope (101), and the second edge (103) having a second opening (105) giving access to the inside of the envelope (101). In addition, the packaged item (100) comprises: documents (106a, 106b, 106c, 106d, 106e) arranged in the envelope (101); a first closure member (107) partially closing the first opening; a second closure member (108) partially closing the second opening (105).

Description

Object packaged with documents arranged in an envelope

Technical field of the invention

The technical field of the invention relates to the packaging of documents. More particularly, the technical field of the invention relates to a packaged object comprising documents, a packaging method for forming at least one packaged object, an installation for forming packaged objects, a packaged pharmaceutical product comprising the packaged product and a method of forming the packaged drug product.

State of the prior art

[0002] It is known to pack a pharmaceutical product such as hyaluronic acid in a box. There is a need according to which the box can comprise several doses of said pharmaceutical product, such as two doses in an example developed below. Therefore, in this example, a practitioner can open the box, extract the two doses to inject them into different patients. The practitioner may need to access a practitioner's leaflet for the product and may need to give each of the two patients a patient leaflet and a patient card. These five documents related to the two-dose pharmaceutical product are arranged in the box with the pharmaceutical product. Conventionally, a production line for forming packaged pharmaceutical products comprises only one robot allowing a single leaflet insertion into the corresponding box, which implies having recourse to several robots to insert the various leaflets and patient cards: the inserting leaflets and patient cards is therefore not easy and slows down the production of packaged pharmaceutical products.

Object of the invention

The invention aims to find a solution to facilitate the insertion of documents in a box.

To this end, the invention relates to a packaged object comprising:

• an envelope comprising first and second opposite edges, the first edge comprising a first opening giving access to the interior of the envelope, and the second edge comprising a second opening giving access to the interior of the envelope;

• documents arranged in the envelope;

• a first closure member partially closing the first opening;

• a second closure member partially closing the second opening. [0005] Such a packaged object has the advantage that its manipulation makes it possible to simultaneously manipulate the documents it contains, thus facilitating the insertion of several documents in a box. Furthermore, due to its structure, the packaged object allows easy extraction of the documents from the envelope, in particular when one of the first and second closure members is removed or cut.

[0006] The packaged object may also include one or more of the following characteristics:

• the first closure member is a pad glued to two opposite sides of the envelope, a portion of the first closure member being arranged across the first opening;

• the second closure member is a pellet glued to the two opposite sides of the envelope, a portion of the second closure member being arranged across the second opening;

• the first closure member is temporarily bonded to the two opposite sides of the envelope;

• the envelope is made of paper;

• the envelope comprises a folded sheet so that two opposite portions of the sheet overlap, said two portions being glued together;

• the documents are such that: a first of the documents is a first patient notice; a second of the documents is a first patient card stuck to the first of the documents; a third of the documents is a second patient notice; a fourth of the documents is a second patient card stuck to the third of the documents; one-fifth of the documents is a practitioner's manual;

• the first to fifth documents relate to a pharmaceutical product;

• each of the documents has a marker;

• the envelope has a marker;

• the first edge has two superimposed notches.

The invention also relates to a packaging method comprising at least one step of forming a packaged object, the step of forming the packaged object comprising the following steps: a) providing documents; b) forming an envelope in which the documents provided in step a are arranged, the envelope comprising first and second opposite edges, the first edge comprising a first opening giving access to the interior of the envelope, and the second edge comprising a second opening giving access to the interior of the envelope; c) placing a first closure member to partially close the first opening; d) placing a second closure member to partially close the second opening.

[0008] The packaging process may also include one or more of the following characteristics

• step b) includes the following steps: b.l) position the documents provided for in step a) in relation to a sheet intended to form the envelope; b.2) folding the sheet so as to locally obtain an overlap of two portions of the sheet and so as to surround the documents with the sheet; b.3) fixing the two portions of the sheet together;

• said documents provided for in step a) are positioned so as to form a stack of documents on the sheet before the execution of step b.2);

• step b) is configured to adapt the overlap of the portions of the sheet according to the total thickness of the documents to be surrounded by the sheet;

• the packaging process comprises a verification step to verify that the documents provided for in step a) are compliant with respect to the expected packaged object, the verification step comprising a step of reading markers each belonging to the one of the documents that the packaged object must include;

• after placing the first closure member, the casing is pivoted about a pivot axis substantially orthogonal to the plane of the casing to position the second edge of the casing appropriately in order to allow the implementation of the step d);

• the packaging process makes it possible to form several packaged objects in a chain, steps a) to d) being implemented for each of the packaged objects.

The invention also relates to an installation for forming packaged objects, the installation comprising a conveying device and a first station configured to successively deposit sheets on the conveying device, the conveying device being configured to bring each of the sheets successively:

• at a second station configured to deposit documents above said sheet as it passes through said second station;

• at a third station configured to fold the sheet in order to obtain an envelope in which the deposited documents are arranged, said envelope comprising first and second opposite edges, the first edge comprising a first opening giving access to the interior of the envelope, and the second edge comprising a second opening giving access to the interior of the envelope;

• at a fourth station configured to place a first closure member at the first edge of the envelope in order to partially close the first opening and to place a second closure member at the second edge of the envelope in order to partially close the second opening.

The invention also relates to a packaged pharmaceutical product comprising: a packing box; a packaged object as described and arranged in the packaging box; and the pharmaceutical product arranged in the packaging box.

The invention also relates to a process for forming at least one packaged pharmaceutical product comprising:

• a stage of supplying a packaging box;

• a step of inserting a packaged object as described in the packaging box;

• a step of inserting the pharmaceutical product into the packaging box.

[0012] Other advantages and characteristics may emerge from the detailed description which follows.

Brief description of the figures

The invention will be better understood on reading the following detailed description, given solely by way of non-limiting example and made with reference to the accompanying drawings listed below.

[0014] Figure 1 schematically illustrates, in a perspective view, a particular embodiment according to the invention of a packaged object.

[0015] Figure 2 illustrates the packaged object of Figure 1 in a sectional view in a plane parallel to the Z and Y axes of Figure 1.

[0016] Figure 3 schematically illustrates, in a perspective view, a particular embodiment of a single envelope devoid of the documents it must contain and intended to be part of the packaged object.

[0017] FIG. 4 schematically illustrates a partial sectional view of a pharmaceutical product packaged according to a particular embodiment of the invention and showing the inside of a box of this packaged pharmaceutical product in order to visualize the contents of the box namely the pharmaceutical product and the packaged object which contains documents related to the pharmaceutical product.

[0018] Figure 5 schematically illustrates a sheet used to form an envelope for documents as part of a packaging process, according to a particular embodiment of the invention, to form the packaged object.

[0019] Figure 6 schematically illustrates, according to a particular embodiment, a step of the packaging process in which a stack of documents is formed on the sheet of Figure 5.

[0020] Figure 7 schematically illustrates, according to a particular embodiment, a step of the packaging process in which a folding of the sheet of Figure 6 is carried out to form a first flap on the stack of documents.

[0021] Figure 8 schematically illustrates, according to a particular embodiment, a step of the packaging process in which a folding of the sheet of Figure 7 is carried out to form a second flap on the stack of documents and partially cover the first flap.

[0022] Figure 9 schematically illustrates, according to a particular embodiment, steps of the packaging process in which closure members are placed on the envelope obtained in accordance with figure 8.

Figure 10 schematically illustrates, according to a particular embodiment of the invention, an installation for forming packaged objects.

[0024] Figure 11 schematically illustrates an example of a first closure member used to close the envelope of the packaged object.

In these figures, the same references are used to designate the same elements. The elements shown in the various figures are not necessarily drawn to scale in order to facilitate understanding of the figures.

detailed description

[0026] By “substantially orthogonal”, it is meant in the present description orthogonal or orthogonal to within plus or minus 10%.

An orthonormal XYZ reference is defined, this reference is represented by the X, Y and Z axes in Figures 1 and 2. The orthonormal XYZ reference gives the reference frame of the packaged object 100.

The invention relates to the packaged object 100, an example of which is illustrated in Figures 1 and 2. Such a packaged object 100 comprises an envelope 101. Figure 3 shows an example of this envelope 101 alone with lines in dotted line representing the hidden lines of this envelope 101.

The envelope 101 has first and second opposite edges 102, 103 (as shown in particular in Figures 1 and 3). The first edge 102 includes a first opening 104 (shown partly in dotted lines in Figure 3) giving access to the interior of the envelope 101. The second edge 103 includes a second opening 105 giving access to the interior of the envelope 101. The interior of such an envelope 101 is intended to contain documents 106a, 106b, 106c, 106d, 106e.

The packaged object 100 includes the documents 106a, 106b, 106c, 106d, 106e arranged in the envelope 101.

The packaged object 100 comprises a first closure member 107 partially closing the first opening 104 and a second closing member 108 partially closing the second opening 105 as shown in particular in Figure 1. Thus, the first and second Closing members 107, 108 each participate in the closing of the envelope 101 respectively at the first opening 104 and at the second opening 105. In other words, the envelope 101 is closed by the first and second closing members 107, 108.

It follows from what has been described above that these first and second closure members 107, 108 each only close respectively part of the first opening 104 and part of the second opening 105. This makes it possible to close the envelope 101 in a suitable manner according to its thickness. Furthermore, this facilitates, if necessary, the removal of the first closure member 107 when the latter is glued to the casing 101 by limiting the bonding surfaces between the casing 101 and the first closure member 107 . [0033] By "the closing of the envelope 101 by the first and second closing members 107, 108", it is understood that the first and second closing members 107, 108 oppose the withdrawal of the documents 106a, 106b , 106c, 106d, 106e present in the casing 101 when these first and second closure members 107, 108 partially block the first and second openings 104, 105 respectively. Thus, there is no need for the first and second closure members 107, 108 seal respectively the first and second openings 104, 105 as long as they ensure the maintenance of the documents 106a, 106b, 106c, 106d, 106e in the envelope 101 by respectively opposing the passage of said documents 106a, 106b, 106c, 106d, 106e through the first opening 104 and through the second opening 105 from which it follows that the envelope 101 is considered closed.

[0034] In particular, the first and second closure members 107, 108 are separate from the casing 101, that is to say they are not an integral part thereof and they cooperate with the casing 101 to partially close its first and second openings 104, 105.

[0035] The packaged object 100 has the advantage of being able to include several documents 106a, 106b, 106c, 106d, 106e contained in the envelope 101 without having to tighten/compress them significantly, for example in the sense that they can move in the envelope 101 but cannot leave it because the first closure member 107 hinders the passage of the documents 106a, 106b, 106c, 106d, 106e through the first opening 104 and because the second closure member 108 hinders the passage documents 106a, 106b, 106c, 106d, 106e through the second opening 105.

The first opening 104 may be the preferred one to allow the extraction of the documents 106a, 106b, 106c, 106d, 106e when they are arranged in the envelope 101. Thus, after removal or cutting of the first closure member 107 , the documents 106a, 106b, 106c, 106d, 106e can easily be extracted from the envelope 101 by a person.

Another advantage of the packaged object 100 as described is that the packaged objects 100 can be transported en masse while avoiding mixing the documents 106a, 106b, 106c, 106d, 106e: the use of envelopes 101 allows maintain an appropriate distribution of the documents 106a, 106b, 106c, 106d, 106e in the envelopes 101. Another advantage of the packaged object 100 lies in the fact that the documents 106a, 106b, 106c, 106d, 106e are gathered, while retaining if necessary a flexibility allowing the packaged object 100 to be curved, in order to be manipulated simultaneously by manipulation of the packaged object 100, for example by a robot. Consequently, the documents 106a, 106b, 106c, 106d, 106e can easily be inserted by the robot into a box 2001 simultaneously without modifying the usual production chains intended for the insertion of a single document into the box 2001 (see by example figure 4). The packaged object 100 as described therefore has the advantage of being able to mechanically resist manipulation, thus allowing simultaneous manipulation of the documents 106a, 106b, 106c, 106d, 106e. The first closure member 107 and/or the second closure member 108 can be bonded to the envelope 101, for example on two opposite faces 109, 110 of the envelope 101 (in particular opposite faces 109, 110 according to the Z axis in FIGS. 1 and 2) and so as to partially close the first opening 104 by the first closing member 107 and/or so as to partially close the second opening 105 by the second closing member 108.

[0040] For example, the first closure member 107 may comprise a polypropylene part, one face of which is wholly or partly covered with an adhesive, for example fugitive, to ensure the desired bonding of the first closure member 107 to the envelope 101; this glue belonging to the first closure member 107.

[0041] For example, the second closure member 108 may comprise a polypropylene part, one face of which is wholly or partly covered with an adhesive to ensure the desired bonding of the second closure member 108 to the casing 101; this glue belonging to the second member 108 of closure.

The two opposite faces 109, 110 of the envelope 101 are preferably so-called main faces interconnected by opposite sides 117, 118 of the envelope 101 (in particular opposite sides 117, 118 along the Y axis in Figures 1 and 2).

[0043] The first closure member 107 may be a pad glued to the two opposite faces 109, 110 of the casing 101, a portion (not visible in the figures) of the first closure member 107 being arranged across the first opening 104.

[0044] The second closure member 108 may be a pad glued to the two opposite faces 109, 110 of the casing 101, a portion 111 (visible in FIG. 1) of the second closure member 108 being arranged across the second opening 105. [0045] As applicable to the first closure member 107 and/or to the second closure member 108, the pastille glued as a closure member makes it possible to participate in the function of holding the documents 106a, 106b, 106c , 106d, 106e in the envelope 101 in particular because its portion across the opening concerned (the first opening 104 or the second opening 105) opposes the passage of the documents 106a, 106b, 106c, 106d, 106e. In addition, such a patch has the advantage of being able to adapt to the thickness of the envelope 101, measured parallel to the Z axis, without complication when folding the patch to stick it on the two opposite faces 109, 110 of the casing 101. Furthermore, the pellet has the advantage of being able to stick to small surfaces, thus limiting the closing of the opening concerned.

[0046] By "pad", it is for example understood a member that can adopt in whole or in part a disc shape.

[0047] According to one embodiment, the first closure member 107 is bonded fleetingly to the two opposite faces 109, 110 of the envelope 101. The advantage of using such bonding is that it makes it easier to open of the packaged object 100 to extract the documents 106a, 106b, 106c, 106d, 106e therefrom. According to this embodiment, the second closure member 108 can be glued in a non-transient manner on the two faces 109, 110 opposite the envelope 101 since the documents 106a, 106b, 106c, 106d, 106e will be intended to be removed via the first opening 104 once the first closure member 107 has been removed in whole or in part from the envelope 101.

[0048] For example, the first closure member 107 glued in a fugitive manner has a bonding surface formed by fugitive glue. In the technical field of bonding, fugitive glue is also called “repositionable glue”. Such fugitive glue has the advantage of adhering to a large number of supports while allowing removable adhesion in the sense that the fugitive glue can be peeled off in particular manually at any time from the envelope 101, thus allowing the easy removal of the first closure member 107. Fugitive glue can be defined as a glue that does not fuse with the support on which it adheres.

In order to facilitate the removal of the documents 106a, 106b, 106c, 106d, 106e, the first opening 104 may include a "nudge". A thumbs up can be defined as a particular shape at the level of the first opening 104 authorizing the seizure of the documents 106a, 106b, 106c, 106d, 106e for example between the thumb and the index finger of a person when they are arranged in the casing 101. For example, as illustrated in FIG. 3, the two faces 109, 110 of the casing 101 each comprise an edge 119, 120 delimiting a corresponding portion of the first opening 104, each of said edges 119, 120 of the first and second faces 109, 110 locally presenting a notch 121, 122. The notches 121, 122 are arranged in particular in a superimposed manner so as to allow the documents 106a, 106b, 106c, 106d, 106e to be pinched between two fingers of a person to facilitate their extraction from the envelope 101. According to another formulation, the first edge 102 (and in particular the first opening 104) may have two notches 121, 122 superimposed and in particular formed respectively in the two faces 109, 110 of the envelope 101.

In particular, the first closure member 107 covers the two notches 121, 122 within the packaged object 100.

The first closure member 107, when glued fleetingly to the casing 101, may include a tab 123 for gripping (notably visible in Figures 1 and 11). This gripping tab 123 is not glued to the envelope 101 and has a latitude of movement allowing it to be grasped by a person in order to exert a force on the first closure member 107 to take it off in whole or in part. of the envelope 101. The tongue 123 can be arranged in extension of a body 124 of the first closure member 107, said body 124 being glued to the envelope 101 in a fleeting manner while the tongue 123 devoid of glue can be gripped . Body 124 may have a circular shape and tongue 123 may extend radially from said body 124 as shown for example in Figure 11. Body 124 and tongue 123 may be made of polypropylene.

The second closure member 108 can itself be bonded in a non-transient manner, that is to say permanently to the envelope 101. The second closure member 108 can then comprise a suitable bonding surface . The envelope 101 can advantageously be made of paper. This has the advantage of allowing the formation of an envelope 101 of flexible material which can easily be gripped by a robot. Another advantage of paper is that it can be easily recycled, thus limiting pollution. For example, the paper used can have a weight equal to 115 g/m ² , this being only an example in the sense that other weights can also be used. According to a particular embodiment, the envelope 101 comprises a sheet 116 folded so that two opposite portions 112, 113 of the sheet 116 overlap, said two portions 112, 113 being glued together (Figure 2) by example with a standard glue making it possible to permanently fix the two portions 112, 113 to each other. In particular, the two opposite portions 112, 113 correspond to two opposite edges of the sheet 116 and are delimited respectively by a surface coming from one of the two sides of the sheet 116 and by a surface coming from the other of the two sides of of the sheet 116. The technical advantage linked to such an overlap is that it is possible to limit the tightening of the documents 106a, 106b, 106c, 106d, 106e in the envelope 101. Indeed, such a sheet 116 used during of the packaging allows the documents 106a, 106b, 106c, 106d, 106e to be stacked on the sheet 116 which is then folded, for example twice, to form the envelope 101 around the documents 106a, 106b, 106c, 106d, 106e. Thus, the envelope 101 can be formed according to the documents 106a, 106b, 106c, 106d, 106e that it must contain while preventing the documents 106a, 106b, 106c, 106d, 106e from being too constrained in the envelope. 101 in order to facilitate subsequent extraction after removal or cutting of the first closure member 107.

When the casing 101 adopts the form of a sheath, it is preferably sealed along its length, parallel to the axis X by gluing the portions 112, 113 of the sheet 116 together and closed at its longitudinal ends by the first and second closure members 107, 108.

According to a particular embodiment, the documents 106a, 106b, 106c, 106d, 106e are linked to a product, this product possibly being a pharmaceutical product. By relating to the product, it is understood that the documents 106a, 106b, 106c, 106d, 106e may present information relating to said product. Thus, the documents 106a, 106b, 106c, 106d, 106e can include notices linked to the pharmaceutical product. The packaged object 100 therefore makes it possible to associate several leaflets with the same 2002 pharmaceutical product.

Thus, the documents 106a, 106b, 106c, 106d, 106e can be such that: a first 106a of the documents 106a, 106b, 106c, 106d, 106e is a first patient notice; a second 106b of the documents 106a, 106b, 106c, 106d, 106e is a first patient card glued to the first 106a of the documents 106a, 106b, 106c, 106d, 106e for example by fleeting gluing; a third 106c of documents 106a, 106b, 106c, 106d, 106e is a second patient notice; a fourth 106d of documents 106a, 106b, 106c, 106d, 106e is a second patient card glued to the third 106c of documents 106a, 106b, 106c, 106d, 106e for example by fleeting gluing; a fifth 106e of documents 106a, 106b, 106c, 106d, 106e is a practitioner's note; the first to fifth documents 106a, 106b, 106c, 106d, 106e are related to the 2002 pharmaceutical product. This allows, for example, a practitioner to have access to a pharmaceutical product 2002 comprising at least two doses while allowing, if necessary, to read the practitioner's instructions for this pharmaceutical product 2002 and to sleep with each patient who has received a dose of the product 2002 pharmaceutical its patient card and its patient leaflet. Of course, if ever the pharmaceutical product 2002 comprises more than two doses, the documents may contain one or more additional pairs of patient card and patient notice pasted together, in particular fleetingly. These first through fifth documents 106a, 106b, 106c, 106d, 106e are physically distinct although some may be identical. The stacking of these first to fifth documents 106a, 106b, 106c, 106d, 106e is in particular provided according to the reading direction for the practitioner: along the Z axis which then gives the direction of the height, it is then possible to find successively from top to bottom the fifth document 106e, the third document 106c, the fourth document 106d, the first document 106a and the second document 106b. Therefore, the packaged object 100 can be inserted into the box 2001 containing the pharmaceutical product 2002 as shown, for example, in Figure 4. When the pharmaceutical product 2002 comprises two doses, the first and second documents 106a, 106b joined together by gluing can be given to a first patient and the third and fourth documents 106c, 106d joined together by gluing can be given to a second patient other than the first patient while the practitioner can keep the practitioner's manual (the fifth document 106e) to its destination.

[0059] By “practitioner”, it is understood in the present description a person from the medical profession such as, for example, a doctor. The practitioner may in particular be the person mentioned above who extracts the documents 106a, 106b, 106c, 106d, 106e from the envelope 101.

In the present description, a "practitioner's manual" is a manual for the use of the practitioner.

For example, the practitioner's notice can be linked to the pharmaceutical product 2002 which can be an injectable product. The practitioner's instructions may indicate to the practitioner: the composition of the injectable product and how to inject it.

In the present description, a “patient notice” is a notice intended for a corresponding person. The patient may be the person who will receive or who has received the injectable product by injection.

[0063] For example, the patient leaflet can be linked to the injectable product and the content of the patient leaflet can indicate to the patient one or more information, for example defined by a commission such as a drug agency, in relation to the injection of the injectable product.

[0064] In the present description, a “patient card” can give one or more additional information(s) to the patient; for example, the patient card makes it possible to determine injection points on the patient's face, thus allowing the patient to be informed of the injection sites of the injectable product on his face. The injectable product can be hyaluronic acid.

In the context of a use of the packaged object 100 in the pharmaceutical field, this allows, for example, the practitioner who can make chain injections to have an envelope 101 containing all the documents 106a, 106b, 106c , 106d, 106e necessary and easy to open.

Each of the documents 106a, 106b, 106c, 106d, 106e can include a marker 114 (FIG. 6). This makes it possible to identify the documents 106a, 106b, 106c, 106d, 106e for example during the formation of the packaged object 100. It is then possible to be sure that all the documents 106a, 106b, 106c, 106d, 106e desired are well within the packaged object 100.

The envelope 101 can include a marker 115 (FIGS. 1, 3 and 9). This makes it possible to identify the envelope 101 and therefore the contents of the envelope 101 of the packaged object 100. A marker 114, 115 within the meaning of the present description, whether this is an envelope marker 115 or a document marker 114, can be a two-dimensional barcode such as a QR code. Thus, the marker 114, 115 can make it possible to identify, where appropriate, a document or envelope content. The marker may be the same for identical documents or for envelopes 101 having the same content. For example, for a given envelope 101, the markers of the patient notices can be identical but be different from the markers of the patient cards and from the marker of the practitioner's note, the markers of the patient cards can be identical but be different from the marker of the practitioner's note . The purpose of the markers 114, 115 is to ensure, during the formation of the packaged object 100, the perfect pairing of the documents 106a, 106b, 106c, 106d, 106e with a given envelope 101 for a product to be linked with the packaged object. 100: we are then sure that an envelope 101 contains the correct documents 106a, 106b, 106c, 106d, 106e and it is possible to know the contents of the envelope 101 by simply reading its marker 115.

[0070] It follows from what has been described above that there is a need to find a solution for easily forming/manufacturing one or more packaged objects 100 and this, if necessary, in a reproducible manner and with a satisfactory production rate. To meet this need, the invention also relates to a packaging method comprising at least one step of forming the packaged object 100 in particular as described in the present description. A particular embodiment of the step of forming the packaged object 100 is illustrated in FIGS. 5 to 9.

In particular, the step of forming the packaged object 100 comprises the following steps: a) providing the documents 106a, 106b, 106c, 106d, 106e, these documents 106a, 106b, 106c, 106d, 106e also being called documents 106a, 106b, 106c, 106d, 106e to be packaged (FIG. 6), each of said documents 106a, 106b, 106c, 106d, 106e possibly comprising its marker 114; b) forming the envelope 101 as described in which the documents 106a, 106b, 106c, 106d, 106e provided in step a) are arranged (FIGS. 5 to 8); c) placing the first closure member 107 to partially close the first opening 104 (FIG. 9); d) placing the second closure member 108 to partially close the second opening 105 (FIG. 9).

[0072] It was mentioned above that the use of a sheet 116 was particularly suitable for forming the envelope 101, in particular in the sense that this makes it possible to size the envelope 101 according to the documents 106a, 106b , 106c, 106d, 106e provided in step a) of the packaging process, for example with a view to facilitating their extraction from the envelope 101. Thus, step b) may comprise the following steps: b.l) positioning the documents 106a, 106b, 106c, 106d, 106e provided in step a) relative to the sheet 116 intended to form the envelope 101, for example in the form of a stack of documents 106a, 106b, 106c, 106d, 106e placed on the sheet 116 as shown in Figure 6; b.2) folding the sheet 116 so as to locally obtain an overlap of the two portions 112, 113 of the sheet 116 and so as to surround the documents 106a, 106b, 106c, 106d, 106e by the sheet 116, this step b. 2) can be carried out in two stages by successively forming two folds, also called flaps, as shown by the passage from FIG. 6 to FIG. 7 then the passage from FIG. 7 to FIG. 8; b.3) fixing the two portions 112, 113 of the sheet 116 together, this being able for example to be achieved by gluing in particular by applying glue, for example for hot application, on one of the folds/flap of the sheet 116 before putting the other folds/flap in contact with the glue.

[0073] In particular, step b) can include a step consisting in providing the sheet 116, for example with its notches 121, 122 as described above (see for example FIG. 5).

To facilitate the folding of the sheet 116, step b) can also include a step of creasing the sheet 116 prior to its folding. The aim is to form grooves 125, 126 (see for example FIGS. 5 to 6 for groove 126 and FIGS. 5 to 7 for groove 125) in sheet 116 in order to facilitate its folding. In particular, step b) can include the step consisting in providing the sheet 116 and the creasing step implemented before step b.l). The creasing step can be implemented using one or more rollers. Thus, the opposite sides 117, 118 of the envelope 101 may have been obtained following creasing of the sheet 116.

According to a particular implementation of the packaging method, said documents 106a, 106b, 106c, 106d, 106e provided in step a) are for example positioned so as to form the stack of documents 106a, 106b, 106c , 106d, 106e on sheet 116 before execution of step b.2). In other words, step b1) can be such that said stack of documents 106a, 106b, 106c, 106d, 106e is formed on sheet 116. This has the advantage of adapting the formation of envelope 101 to the stack of documents 106a, 106b, 106c, 106d, 106e to be packaged. As a result, it is possible to obtain the packaged object 100 allowing easy removal of the documents 106a, 106b, 106c, 106d, 106e from the envelope 101, the formation of which will have advantageously been adapted to the cumulative thickness of the documents 106a, 106b, 106c, 106d, 106e superimposed.

Step b) can be configured to adapt the overlap of the portions 112, 113 of the sheet 116 according to the total thickness of the documents 106a, 106b, 106c, 106d, 106e to be surrounded by the sheet 116. Thus , for example, knowing the documents 106a, 106b, 106c, 106d, 106e to be present in the envelope 101, the creasing step can be adapted to form the grooves 125, 126 in the sheet 116 in order that the folding of the sheet (step b.2)) at the level of the grooves 125, 126 makes it possible to obtain the desired adapted overlap of the portions 112, 113 of the sheet 116. This adaptation can be provided in a predetermined manner depending on the documents 106a, 106b, 106c, 106d, 106e to be wrapped: for this a standard sample may have been made beforehand to determine the desired overlap; the aim being in particular to facilitate the removal of the documents 106a, 106b, 106c, 106d, 106e by a practitioner wearing gloves. This makes it possible to adapt the envelope 101 to the cumulative thickness of the documents 106a, 106b, 106c, 106d, 106e during the implementation of the packaging process: the documents 106a, 106b, 106c, 106d, 106e are not therefore not too tight in the envelope 101 so as to facilitate their extraction. The total thickness of the documents 106a, 106b, 106c, 106d, 106e, or cumulative thickness of the documents 106a, 106b, 106c, 106d, 106e, corresponds to the sum of the thickness of each of the documents 106a, 106b, 106c, 106d , 106th planned in step a).

[0077] The packaging process may include a verification step to verify that the documents 106a, 106b, 106c, 106d, 106e provided for in step a) are compliant with respect to the expected packaged object 100, the step of verification comprising a step of reading markers 114 each belonging to one of the documents 106a, 106b, 106c, 106d, 106e that the packaged object 100 must include. 100 given that it includes the correct documents 106a, 106b, 106c, 106d, 106e. Thus, the verification step can be such that any document 106a, 106b, 106c, 106d, 106e detected as non-compliant can be ejected with a view to being discarded or destroyed and replaced by a document 106a, 106b, 106c, 106d, 106th conforming corresponding to obtain the desired packaged object 100. Thus, when all the documents 106a, 106b, 106c, 106d are verified as compliant, the documents 106a, 106b, 106c, 106d provided are obtained (step a)) and step b) can be implemented. The quality of the process of packaging the documents 106a, 106b, 106c, 106d, 106e is thus improved because there will be no mixing of the documents 106a, 106b, 106c, 106d, 106e: the packaged object 100 will then present a compliance with what is expected without risk of mixing. Of course, the verification step can include a comparison step markers 104 read during the reading step with expected markers in order to allow the documents 106a, 106b, 106c, 106d, 106e provided in step a) and considered to be in conformity to be obtained. If the envelope 101 also includes a marker 115, a reading of its marker can be correlated with the markers 114 read from the documents 106a, 106b, 106c, 106d, 106e in order to validate that the association between the envelope 101 and the documents 106a, 106b, 106c, 106d, 106e that it contains are compliant, if the association is not compliant then the envelope 101 and the documents 106a, 106b, 106c, 106d, 106e that it contains can be discarded or destroyed. Cameras, in particular arranged within a production installation intended to form packaged objects 100, will thus make it possible to read the markers 114, 115 in order to control the correct progress of the formation of the packaged object 100.

The documents 106a, 106b, 106c, 106d, 106e provided in step a) can each include a marker 114, in particular as described previously, making it possible to identify said document 106a, 106b, 106c, 106d, 106e. In this case the markers 114 of each document 106a, 106b, 106c, 106d, 106e provided for in step a) can be checked at the time of the implementation of step a) or only some of the markers 114 of the documents 106a , 106b, 106c, 106d, 106e can be read and checked if documents have been associated together, for example by gluing as described below. For example, any check highlighting that the document 106a, 106b, 106c, 106d, 106e considered is not compliant leads to discarding or destroying the document 106a, 106b, 106c, 106d, 106e considered and replacing it with a document 106a, 106b, 106c, 106d corresponding compliant.

In the example where the documents provided for in step a) are the first to fifth documents 106a, 106b, 106c, 106d, 106e as described above. The packaging process may include a step of preparing the documents 106a, 106b, 106c, 106d, 106e comprising:

• the formation of at least a first set of documents comprising the first and second documents 106a, 106b glued to each other, preferably fleetingly;

• the formation of at least a second set of documents comprising the third and fourth documents 106c, 106d stuck together, preferably fleetingly;

• a step in which there is provided at least a fifth document 106e.

Step a) consisting in providing the documents 106a, 106b, 106c, 106d, 106e to form the corresponding packaged object 100 can then consist in providing the first set of documents 106a, 106b, the second set of documents 106c, 106d and the fifth document 106a to be packaged within said packaged object 100. The preparation step may also have been carried out upstream of the implementation of the packaging process, for example on one or more corresponding production lines; in this case the packaging process may include a step in which the documents prepared in accordance with the preparation step are provided. In the case where the packaging process makes it possible to form packaged objects 100, step a) can be implemented for each packaged object 100 to be formed by taking:

• a first set of documents 106a, 106b in a stock of first sets of documents 106a, 106b, each first set of documents comprising a corresponding first document 106a and a corresponding second document 106b glued together, preferably fleeting manner;

• a second set of documents 106c, 106d in a stock of second sets of documents 106c, 106d, each second set of documents 106c, 106d comprising a corresponding third document 106c and a corresponding fourth document 106d glued together, preferably fleetingly;

• a corresponding fifth document 106e in a stock of fifth documents 106e.

The first set(s) of documents 106a, 106b may have been obtained in a secure manner by automatic reading, for example using camera(s), markers 114 of the documents of the first set(s) of documents 106a, 106b to ensure that the or each first set of documents 106a, 106b indeed includes the desired documents.

The second set(s) of documents 106c, 106d may have been obtained in a secure manner by automatic reading, for example using camera(s), markers 114 of the documents of the second set(s) of documents 106c, 106d to ensure that the or each second set of documents 106c, 106d indeed includes the desired documents.

If necessary, when performing step a) or when depositing the corresponding documents 106a, 106b, 106c, 106d, 106e to form the stack of documents 106a, 106b, 106c, 106d, 106e on the sheet 116, a check of markers 114, for example of the fifth document 106a, of one of the documents of the first set of documents 106a, 106b and of one of the documents of the second set of documents 106c, 106d can be carried out in order to ensure that the correct documents will be deposited before folding and gluing the sheet 116 in order to obtain the desired envelope 101; for example, any second set of non-compliant documents is preferentially discarded or destroyed then replaced by a second compliant set of documents and any first non-compliant set of documents is preferentially discarded or destroyed then replaced by a second compliant set of documents. Here, as the content of each first set of documents 106a, 106b and of each second set of documents 106c, 106d could have been verified beforehand by reading corresponding markers 114, the control of only one of the documents of each of the first and second sets of documents is sufficient to ensure that the correct documents are deposited before folding and gluing the sheet 116.

According to one embodiment, after placing the first closure member 107, or the second closure member 108, the casing 101 is pivoted, for example through 180°, along a pivot axis substantially orthogonal to the plane of the envelope 101 to position the second edge 103 of the envelope 101, respectively the first edge 102 of the envelope 101, in an appropriate manner, in order to allow the implementation of the step d), respectively the implementation of step c). This makes it possible to close the envelope 101 with the first and second closing members 107, 108 in the same equipment or in two successive equipments of a production line oriented in the same way. The pivoting along the pivot axis substantially orthogonal to the plane of the envelope 101 makes it possible to avoid any reversal of the envelope 101 which would involve a risk of the documents 106a, 106b, 106c, 106d, 106e coming out of the envelope 101 before its complete closure.

Advantageously, the packaging method makes it possible to form several packaged objects 100 in a chain, steps a) to d) being implemented for each of the packaged objects 100. This makes it possible to obtain a rate of formation of the objects packed 100 satisfactory.

The invention also relates to an installation 1000 for forming packaged objects 100, also called a production line. An example of such a setup

1000 is illustrated in FIG. 10. Such an installation 1000 makes it possible to obtain the wrapped objects 100 as described and can preferentially implement the packaging method described. Thus, the installation 1000 can comprise the material means for the implementation of the packaging process. In general, the installation 1000 comprises a conveying device 1001 and a first station 1002 configured to successively deposit sheets 116 on the conveying device 1001, the device

Conveying 1001 being configured to bring each of the sheets 116 successively:

• at a second station 1003 configured to deposit documents 106a, 106b, 106c, 106d, 106e (these documents 106a, 106b, 106c, 106d, 106e being those to be arranged in the envelope 101 of a corresponding packaged object 100) above said sheet 116 as it passes through said second station 1003,

• at a third station 1004 configured to fold the sheet 116 in order to obtain the envelope 101 as described previously in which the documents 106a, 106b, 106c, 106d, 106e filed are arranged;

• at a fourth station 1005 configured to place the first closing member 107 at the first edge 102 of the envelope 101 in order to partially close the first opening 104 and to place the second closing member 108 at the second edge 103 of the envelope 101 in order to partially close the second opening 105.

The first to fifth stations 1002, 1003, 1004, 1005 are shown schematically circled in dotted lines in Figure 10. In Figure 10, the arrows shown on the conveying device 1001 make it possible to diagram the path of the sheets 116. A station 1013 creasing (represented circled in dotted lines) can be arranged between the first station 1002 and the second station 1003 to suitably crease each sheet 116 passing through the crease station 1013 in order to facilitate the folding of each of the sheets 116 in the third station 1004.

A particular embodiment is now described in relation to FIG. 10 in which the first station 1002 comprises a depositing device 1006 configured to deposit the sheets 116 successively on the conveying device 1001 . Then, the deposited sheets 116 travel along a path defined by the conveying device 1001 so as to pass through the creasing station 1013 comprising for example suitable equipment 1014, such as for example one or more rollers, making it possible to form grooves intended for the folding of the sheets 116, then by the second 1003 station which comprises in the illustrated example first, second and third depositing devices 1007, 1008, 1009 each configured to deposit at least one corresponding document 106a, 106b, 106c, 106d, 106e . For example, the second item 1003 is such that:

• its first depositing device 1007 makes it possible to deposit the first and second documents 106a, 106b glued together in particular fleetingly;

• its second depositing device 1008 makes it possible to deposit the third and fourth documents 106c, 106d glued together in particular fleetingly above the first and second documents 106c, 106d glued together;

• its third depositing device 1009 makes it possible to deposit the fifth document 106e above the third and fourth documents 106c, 106d glued together.

As a result, on leaving the second station 1003, the documents 106a, 106b, 106c, 106d, 106e of a packaged object 100 to be formed are superimposed on a corresponding sheet 116: it is then necessary to form the envelope 101 around the Documents 106a, 106b, 106c, 106d, 106e. For this purpose, the third station 1004 comprises for example a folding and gluing device 1010 configured to fold two parts of the sheet 116 over the documents 106a, 106b, 106c, 106d, 106e in order to obtain the portions 112, 113 of sheet 116 overlapping and glued together. To perform the gluing, the folding and gluing device 1010 can fold a first part of the sheet 116 over the documents 106a, 106b, 106c, 106d, 106e from which it follows that one of the portions 112 of the sheet 116 is oriented upwards, thus allowing the device 1010 for folding and gluing to glue all or part of said portion 112 before folding a second part of the sheet 116 over the portion 112 glued in whole or in part from which it results the desired overlap of the portions 112, 113 of the sheet 116 as well as the gluing of the portions 112, 113 of the sheet 116. On leaving the third station 1004, each sheet 116 introduced into the third station 1004 is in the form of a envelope 101 with first and second opposite edges 102, 103 open and in which are the documents 106a, 106b, 106c, 106d, 106e. Each envelope 101 obtained at the output of the third station 1004 then passes through the fourth station 1005 in order to receive there its first and second closure members 107, 108 each glued to the two faces 109, 110 of the envelope 101 allowing the documents 106a, 106b, 106c, 106d, 106e to be held in the envelope 101. For example, the third station 1007 comprises first and second devices 1011, 1012 for closing the envelope 101 to place the first and second members 107, 108 closure. In the example of FIG. 10, the first and second devices 1011, 1012 for closing the envelope 101 are arranged along the conveying device 1001 and on opposite edges of the conveying device 1001 so that the first and second members 107 , 108 are placed without having to rotate the envelope 101. In Figure 10, although not shown, notches 121, 122 may be present for each sheet 116.

It follows from what has been described above that the invention also relates to a packaged pharmaceutical product 2000, an exemplary embodiment of which is illustrated in FIG. 4. This packaged pharmaceutical product 2000 comprises:

• a 2001 packing box;

• a packaged object 100 as described and arranged in the packaging box 2001; And

• the 2002 pharmaceutical product arranged in the 2001 packaging box.

Such a packaged pharmaceutical product 2000 has the advantage that the documents 106a, 106b, 106c, 106d, 106e related to the pharmaceutical product 2002 are packaged within the same packaged object 100 which can be easily opened by the practitioner.

The invention also relates to a process for forming at least one packaged pharmaceutical product 2000 comprising:

• a stage of supplying a 2001 packaging box;

• a step of inserting a packaged object 100 as described in the packaging box 2001;

• a step of inserting the pharmaceutical product 2002 into the packaging box 2001.

Such a forming method has the advantage of allowing the rapid formation of the packaged pharmaceutical product 2000 in the sense that several documents 106a, 106b, 106c, 106d, 106e can be inserted into the packaging box 2001 at one time. Of course, this forming process may include a step consisting in providing the packaged object 100 or a step of implementing the packaging process to obtain the packaged object 100 to be inserted into the packaging box 2001. This forming method may also allow the formation of multiple packaged pharmaceutical products 2000 resulting from performing the supply and insertion steps for each packaged pharmaceutical product 2000 desired. For example, the flexibility of the packaged object 100 allows a gripper/robot to twist it slightly to extract it more easily from a feeder (i.e. a robot supply magazine).

An example has been described in which the envelope 101 contains five documents 106a, 106b, 106c, 106d, 106e. This example is not limiting in the sense that, depending on the needs, the envelope 101 can contain two or more documents.

[0092] In the present description, “at least one” means in particular one or more. (0093] The packaged object 100 described above has an industrial application in the field of product packaging, in particular pharmaceutical products, which will be associated with several documents 106a, 106b, 106c, 106d, 106e.

Claims

1. Packaged object (100) comprising:

• an envelope (101) comprising first and second opposite edges (102, 103), the first edge (102) comprising a first opening (104) giving access to the interior of the envelope (101), and the second edge (103) comprising a second opening (105) giving access to the interior of the casing (101);

• documents (106a, 106b, 106c, 106e) arranged in the envelope (101);

• a first closure member (107) partially closing the first opening

(104);

• a second closure member (108) partially closing the second opening

(105).

2. Packaged object (100) according to claim 1, characterized in that:

• the first closure member (107) is a pad glued to two opposite faces (109, 110) of the envelope (101), a portion of the first closure member (107) being arranged across the first opening (104 );

• the second closure member (108) is a pellet glued to the two opposite faces (109, 110) of the casing (101), a portion (111) of the second closure member (108) being arranged across the second opening (105).

3. Packaged object (100) according to claim 2, characterized in that the first closure member (107) is bonded transiently to the two opposite faces (109, 110) of the envelope (101).

4. Packaged object (100) according to any one of claims 1 to 3, characterized in that the envelope (101) is made of paper.

5. Object (100) packaged according to any one of claims 1 to 4, characterized in that the envelope (101) comprises a folded sheet (116) so that two opposite portions (112, 113) of the sheet ( 116) overlap, said two portions (112, 113) being glued together.

6. Packaged object (100) according to any one of claims 1 to 5, characterized in that the documents (106a, 106b, 106c, 106d, 106e) are such that: • a first (106a) of the documents (106a, 106b, 106c, 106d, 106e) is a first patient notice;

• a second (106b) of the documents (106a, 106b, 106c, 106d, 106e) is a first patient card stuck to the first (106a) of the documents (106a, 106b, 106c, 106d, 106e);

• a third (106c) of the documents (106a, 106b, 106c, 106d, 106e) is a second patient notice;

• a fourth (106d) of the documents (106a, 106b, 106c, 106d, 106e) is a second patient card stuck to the third (106c) of the documents (106a, 106b, 106c, 106cd 106e);

• a fifth (106e) of the documents (106a, 106b, 106c, 106d, 106e) is a practitioner's note; the first to fifth documents (106a, 106b, 106c, 106d, 106e) being related to a pharmaceutical product.

7. Packaged object (100) according to any one of claims 1 to 6, characterized in that each of the documents (106a, 106b, 106c, 106e) includes a marker (114).

8. Packaged object (100) according to any one of claims 1 to 7 characterized in that the envelope (101) includes a marker (115).

9. Packaging method comprising at least one step of forming a packaged object (100), the step of forming the packaged object (100) comprising the following steps: a) providing documents (106a, 106b, 106c, 106d, 106e); b) forming an envelope (101) in which are arranged the documents (106a, 106b, 106c, 106d, 106e) provided in step a), the envelope (101) comprising first and second edges (102, 103) opposite sides, the first edge (102) comprising a first opening (104) giving access to the interior of the casing (101), and the second edge (103) comprising a second opening (105) giving access to the interior of the envelope (101); c) placing a first closure member (107) to partially close the first opening (104); d) placing a second closure member (108) to partially close the second opening (105).

10. Packaging method according to claim 9, characterized in that step b) comprises the following steps: b.1) positioning the documents (106a, 106b, 106c, 106d, 106e) provided in step a) relative to a sheet (116) intended to form the envelope (101); b.2) folding the sheet (116) so as to locally obtain an overlap of two portions (112, 113) of the sheet (116) and so as to surround the documents (106a, 106b, 106c, 106d, 106e) by the sheet (116); b.3) fixing the two portions (112, 113) of the sheet (116) together.

11. Packaging method according to claim 10, characterized in that said documents (106a, 106b, 106c, 106d, 106e) provided in step a) are positioned so as to form a stack of documents (106a, 106b, 106c, 106d, 106e) on the sheet (116) before performing step b.2).

12. Packaging method according to any one of claims 10 to 11, characterized in that step b) is configured to adapt the overlap of the portions (112, 113) of the sheet (116) according to the thickness total of documents (106a, 106b, 106c, 106d, 106e) to be surrounded by the sheet (116).

13. Packaging method according to any one of claims 9 to 12, characterized in that it comprises a verification step to verify that the documents (106a, 106b, 106c, 106d, 106e) provided in step a ) are consistent with respect to the expected packaged object (100), the verification step comprising a step of reading markers (114) each belonging to one of the documents (106a, 106b, 106c, 106d, 106e) that must include the packaged object (100).

14. Packaging method according to any one of claims 9 to 13, characterized in that after placing the first closure member (107), the envelope (101) is pivoted along a pivot axis substantially orthogonal to the plane of the envelope (101) to position the second edge (103) of the envelope (101) in an appropriate manner in order to allow the implementation of step d).

15. Packaging method according to any one of claims 9 to 14, characterized in that it makes it possible to form several packaged objects (100) in the chain, steps a) to d) being implemented for each of the wrapped objects (100).

16. Installation (1000) for forming packaged objects (100), the installation comprising a conveying device (1001) and a first station (1002) configured to successively deposit sheets (116) on the conveying device (1001) , the conveying device (1001) being configured to bring each of the sheets (116) successively:

• at a second station (1003) configured to deposit documents (106a, 106b, 106c, 106d, 106e) above said sheet (116) during its passage through said second station (1003);

• at a third station (1004) configured to fold the sheet (116) in order to obtain an envelope (101) in which the documents (106a, 106b, 106c, 106d, 106e) deposited are arranged, said envelope (101) comprising first and second opposite edges (102, 103), the first edge (102) comprising a first opening (104) giving access to the interior of the envelope (101), and the second edge (103) comprising a second opening (105) giving access to the interior of the envelope (101);

• at a fourth station (1005) configured to place a first closing member (107) at the first edge (102) of the envelope (101) in order to partially close the first opening (104) and to place a second member (108) closing the second edge (103) of the casing (101) in order to partially close the second opening (105).

17. Packaged pharmaceutical product (2000) comprising:

• a packing box (2001);

• an object (100) packaged according to any one of claims 1 to 8 and arranged in the packaging box (2001); And

• the pharmaceutical product (2002) arranged in the packaging box (2001).

18. Process for forming at least one packaged pharmaceutical product (2000) comprising:

• a step of supplying a packaging box (2001);

• a step of inserting an object (100) packaged according to any one of claims 1 to 8 in the packaging box (2001);

• a step of inserting the pharmaceutical product (2002) into the packaging box (2001).