WO2023056024A1

WO2023056024A1 - Light therapy treatment devices

Info

Publication number: WO2023056024A1
Application number: PCT/US2022/045397
Authority: WO
Inventors: Richard E. Feinbloom; Liviu Steier
Original assignee: Designs For Vision, Inc.
Priority date: 2021-10-01
Filing date: 2022-09-30
Publication date: 2023-04-06

Abstract

Disclosed are a plurality of light therapy devices suitable for providing light that provide for healing of bacterial and viral infection within bodily cavities, wherein the light therapy devices include at least one probe element suitable for insertion into a body cavity through which a light generated by at least one light source may be transferred from the at least one light source so as to apply the light into an area that is substantially near to the bacterial or viral infection. This invention relates to the field of medical examination/diagnosis and treatment and more particularly to a devices utilizing Fluorescent Enhancement Theragnosis technology in the identification and treatment of medical conditions related to a body cavity, such as the nose, ear, throat, vagina, and anus.

Description

LIGHT THERAPY TREATMENT DEVICES

CLAIM OF PRIORTY

[0001] This application claims, pursuant to 35 USC 119, priority to, and the benefit of the earlier filing date of, that provisional application filing in the US Patent and Trademark Office on October 1, 2021 and afforded serial number 63/251,063, the contents of which are incorporated by reference, herein.

BACKGROUND OF THE INVENTION

FIELD OF THE INVENTION

[0002] This invention relates to the field of medical examination/diagnosis and treatment and more particularly to a devices utilizing Fluorescent Enhancement Theragnosis technology in the identification and treatment of medical conditions related to a body cavity, such as the nose, ear, throat, vagina, and anus.

BACKGROUND INFORMATION

[0003] Light based therapy has emerged as a useful tool in locating and identifying infection or bacterial load within bodily tissues and reducing or eliminating the bacterial load within these tissues found to be infected. Light based therapy is intended to provide for photoactivated disinfection, photodynamic therapy and photobiomodulation.

[0004] Photoactivated therapy is based on the use of inactive prodrugs whose biological activity is significantly increased upon exposure to light. See, for example, F. Reeling, W. Szymanski: Beyond Photodynamic Therapy: Photoactivated Cancer Chemotherapy, Curr. Med. Chem., 2018, 24, 4905-4950.

[0005] Photoactivated disinfection (PAD) is based on the concept of photodynamic therapy (PDT). PDT is a treatment method that is associated with the use of a light source and a photosensitizer (PS) that binds to cells and after absorption of light induces a chemical reaction that results in the release of radicals and singlet oxygen. See, for example, Husejnagic S, Lettner S, Laky M, Georgopoulos A, Moritz A, Rausch-Fan X. Photoactivated disinfection in periodontal treatment: A randomized controlled clinical split-mouth trial. J Periodontol. 2019;90:1260- 1269.

[0006] Photobiomodulation (PBM) is a non-invasive method that contributes to pain relief and reduces inflammation, parallel to the enhanced healing and tissue repair processes. See, for example, Dompe, C.; Moncrieff, L.; Matys, J.; Grzech-Lesniak, K.; Kocherova, I.; Bryja, A.; Bruska, M.; Dominiak, M.; Mozdziak, P.; Skiba, T.H.L; Shibli, J. A.; Angelova Volponi, A.;

Kempisty, B.; Dyszkiewicz-Konwihska, M. Photobiomodulation— Underlying Mechanism and Clinical Applications. J. Clin. Med. 2020, 9, 1724.

[0007] Fluorescent Enhancement Theragnosis (FET) has been found use in dental practice to apply light to a patient's mouth to identify bacterial load that are known to exist in the patient's mouth and in cases, reduce the activity the bacterial load.

[0008] However, the light utilized in providing for the identification and reduction of bacterial load may be harmful to the human eye and, thus, eye protection is required for both the patient and the practitioner to avoid either party from inadvertently viewing the harmful light.

[0009] Hence, there is a need in the industry for applying a light therapy to a patient or a patient's body cavity, such as the nose, ear, throat, vagina, and anus while preventing the inadvertent viewing of the light by a practitioner.

SUMMARY OF THE INVENTION

[0010] Disclosed are devices configured to apply light therapy to infection caused by bacteria and viruses within a body cavity.

[0011] In one aspect of the invention, a nasal insertion device is disclosed that comprises a pair of adjustable probe element that may be positioned within the nasal cavities to provide a light source suitable for applying a FET light within the nasal cavities while preventing the light from being viewable by a practitioner. The adjustable probe elements allows for the appropriate positioning of the FET light near or substantially adjacent the infected tissue.

[0012] In one aspect of the invention, a body cavity insertion device is disclosed that comprises at least one adjustable probe element including a FET light source that may be positioned within a bodily cavity while preventing the light from being viewable by a practitioner, wherein the adjustable probe element allows for the positioning the FET light near or substantially adjacent to the infected tissue.

[0013] In one aspect of the invention, the probe elements may include a plurality of a plurality of lighting sources distributed around a distal end of the probe elements to distribute light of one or more wavelengths toward the infected tissue.

[0014] In one aspect of the invention, the probe elements may be composed of an optically clear, semi-rigid or solid material that may be inserted within a bodily cavity.

[0015] In one aspect of the invention, the probe elements may be composed of a plurality of substantially optically clear fiber elements extending from a proximal end to a distal end of the probe element, wherein a plurality of lighting sources are positioned substantially adjacent a proximal end of the fiber elements and the emitted light is transmitted through the proximal end of the substantially optically clear fiber elements along a longitudinal axis of said fiber elements toward a distal end of the fiber elements such that light is distributed toward the infected tissue.

[0016] In one aspect of the invention, the plurality of substantially optical clear fiber elements are arranged in two bundles, wherein one bundle provides light from a proximal end of the fiber elements toward the distal end of the fiber bundles and a second bundle of fiber elements provides light from the distal end of the fiber elements to the proximal end of the fiber bundle.

[0017] In one aspect of the invention, an image capture device (e.g., a camera, a Charge Couple Device (CCD), liquid crystal device (LCD) or a TV camera) is positioned on a distal end of the probe element or the fiber elements, wherein light from images captured by the image capture device may be transmitted from the distal end of the probe and/or fiber bundle to a processing system for view of the infected area.

[0018] In one aspect of the invention, a sleeve element may be positioned on a distal end of the probe element, wherein the sleeve element may be removably attached to the probe element.

[0019] For a better understanding of exemplary embodiments and to show how the same may be carried into effect, reference is made to the accompanying drawings. It is stressed that the particulars shown are by way of example only and for purposes of illustrative discussion of the preferred embodiments of the present disclosure and are presented to clarify the most useful and readily understood description of the principles and conceptual aspects of the invention. In this regard, no attempt is made to show structural details of the invention in more detail than is necessary for a fundamental understanding of the invention, the description taken with the drawings making apparent to those skilled in the art how the several forms of the invention may be embodied in practice.

BRIEF DESCRIPTION OF THE DRAWINGS

[0020] The advantages, nature, and various additional features of the invention will appear more fully upon consideration of the illustrative embodiments described in detail in connection with the accompanying drawings, where like or similar reference numerals are used to identify like or similar elements throughout the drawings:

[0021] FIG. 1 illustrates a perspective view of a first exemplary embodiment of a light therapy device for applying light therapy to a nasal cavity in accordance with the principles of the invention.

[0022] FIG. 2 illustrates a top view of the light therapy device shown in FIG. 1.

[0023] FIG. 3 illustrates a front view of the light therapy device shown in FIG. 1

[0024] FIG. 4 illustrates a side view of the light therapy device shown in FIG. 1.

[0025] FIG. 5 illustrates a perspective view of an exemplary lighting configuration utilized in the exemplary embodiment shown in FIG. 1 in accordance with the principles of the invention.

[0026] FIG. 6 illustrates exemplary lighting configuration in accordance with the principles of the invention.

[0027] FIG. 7 illustrates a second exemplary embodiment of a light therapy device in accordance with the principles of the invention.

[0028] FIG. 8 illustrates a top view of the light therapy device shown in FIG. 7.

[0029] FIG. 9 illustrates a front view of the light therapy device shown in FIG. 7.

[0030] FIG. 10 illustrates a side view, through section B-B shown in FIG. 9, of the light therapy device shown in FIG. 1.

[0031] FIG. 11 illustrates an expanded view of the area designated as fig. 11 in FIG. 10.

[0032] FIG. 12 illustrates a perspective view of the expanded area view shown in FIG.

11.

[0033] FIG. 13 illustrates a perspective view of a third exemplary embodiment of a light therapy device in accordance with the principles of the invention.

[0034] FIG. 14 illustrates a top view of the light therapy device shown in FIG. 13.

[0035] FIG. 15 illustrates a front view of the light therapy device shown in FIG. 13.

[0036] FIG. 16 illustrates a side view, through section C-C shown in FIG. 15, of the light therapy device shown in FIG. 13.

[0037] FIG. 17 illustrates an expanded view of the area designated as fig. 17 in FIG. 16.

[0038] FIG. 18 illustrates afront view of a printed circuit board configuration associated with the light therapy device shown in FIG. 13.

[0039] FIG. 19 illustrates an exploded perspective view of an exemplary embodiment of a probe configuration in accordance with the principles of the invention.

[0040] FIG. 20 illustrates a front view of the exemplary probe configuration shown in FIG. 19.

[0041] FIG. 21 illustrates a prospective view of a distal end of the exemplary probe configuration shown in FIG. 19

[0042] FIG. 22 illustrates a perspective view of a fourth exemplary embodiment of a light therapy device in accordance with the principles of the invention.

[0043] It is to be understood that the figures, which are not drawn to scale, and descriptions of the present invention described herein have been simplified to illustrate the elements that are relevant for a clear understanding of the present invention, while eliminating, for purposes of clarity, many other elements. However, because these omitted elements are well-known in the art, and because they do not facilitate a better understanding of the present invention, a discussion of such elements are not provided herein. The disclosure, herein, is directed also to variations and modifications known to those skilled in the art.

DETAILED DESCRIPTON OF THE INVENTION

[0044] As used herein, the terms "comprises", "comprising", "includes", "including", "has", "having", or any other variation thereof, are intended to cover non-exclusive inclusions. For example, a process, method, article or apparatus that comprises a list of elements is not necessarily limited to only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. In addition, unless expressly stated to the contrary, the term "of' refers to an inclusive "or" and not to an exclusive "or". For example, a condition A or B is satisfied by any one of the following: A is true (or present) and B is false (or not present); A is false (or not present) and B is true (or present); and both A and B are true (or present).

[0045] The terms "a" or "an" as used herein are to describe elements and components of the invention. This is done for convenience to the reader and to provide a general sense of the invention. The use of these terms in the description, herein, should be read and understood to include one or at least one. In addition, the singular also includes the plural unless indicated to the contrary. For example, reference to a composition containing "a compound" includes one or more compounds. As used in this specification and the appended claims, the term "or" is generally employed in its sense including "and/or" unless the content clearly dictates otherwise.

[0046] All numeric values are herein assumed to be modified by the term "about," whether or not explicitly indicated. The term "about" generally refers to a range of numbers that one of skill in the art would consider equivalent to the recited value (i.e., having the same function or result). In any instances, the terms "about" may include numbers that are rounded (or lowered) to the nearest significant figure.

[0047] FIG. 1 illustrates a perspective view of a first exemplary embodiment of a light therapy device 100 for applying light therapy to a nasal cavity in accordance with the principles of the invention.

[0048] Light therapy device 100 comprises housing 110 and cover 120 wherein cover 120, composed of a silicon or similar flexible material, seals the interior of housing 110 from exposure to outside elements. Within housing 110 is a printed circuit board (not shown) including conventional electronic components, such as resistors, capacitors, transistors, diodes, etc., and/or integrated circuits, such a Field Programmable Gate Arrays (FPGAs) and Application Specific Integrated Circuits (ASICs) (i.e., electronic circuits or circuitry) that may be used to control an application of voltage to at least one lighting source as described, herein. Power to the electronic components on the not shown printed circuit board may be provided through a wired connection (as shown by wire 140) to a remote power source (not shown) or by a conventional, or a rechargeable, battery (not shown) that may be contained within or attached to housing 110.

[0049] Further illustrated on housing 110 are sensors (or switches) 112, 114 that control an application of a voltage provided to printed circuit board (not shown) to be applied to one or more lighting sources as described, herein.

[0050] In this illustrated embodiment, two sensors 112, 114 are shown, wherein each sensor controls the application of voltage to a corresponding one of the (not yet discussed) lighting sources. Alternatively, a single sensor (e.g., 112) may be utilized to apply voltage to the one or both of the not yet discussed lighting sources.

[0051] Cover 120, composed of a flexible or pliable material, e.g., silicon, includes an edge 115 that may be inserted into housing 110 to retain cover 120 in place. Alternatively, cover 120 may be sized to slide over housing 110. Cover 120 may be removably attached to housing 110 to allow cover 120 and cups 121 to be cleaned.

[0052] Cover 120 comprises blocking elements (e.g., inverted cups) 122, 124 that are configured to mold or conform to an opening of a passage or body cavity and to block light from escaping the passage opening. Although elements 122, 124 are shown as inverted cups, it would be recognized that blocking elements 122, 124 may include other shapes, such as a pyramid or trapezoid that engage a body cavity to block light from exiting the body cavity.

[0053] Within blocking elements 122, 124 are illustrated pass-throughs 126, 128, respectively. Pass-throughs 126, 128 are sized to allow corresponding extension rods or probe elements 132, 134 to slide therethrough, while retaining rods 132, 134 substantially stationary. [0054] Positioned on a front surface of cover 120 is shown cover sensor 130. Cover sensor 130 provides an indication to the electronic circuitry on the printed circuit board (not shown) contained within housing 110 that light therapy device 100 is properly positioned so as enable the application of light to the body passage (e.g., nasal cavity) while blocking light from exiting the nasal cavity. Cover sensor 130 may comprise at least one of a contact sensor, a proximity sensor, and a heat sensor that is activated when in contact or proximity to the body cavity; or measure a typical heat associated with a patient.

[0055] Further illustrated are probe elements 132, 134 insertable into passthroughs 126, 128, respectively. Probe elements 132, 134, which may be composed of a flexible material (e.g., silicon) or similar material that may be inserted into a body passage (e.g., a nasal passage). Probe elements 132, 134 may further be composed of a material that may be rigid, flexible or pliable (e.g., may be flexed into a desired position or configuration). In one aspect of the invention, probe elements 132, 134 may be composed of a solid material (e.g., a rod), which may be optically clear, translucent or frosted or may be an optically clear, translucent or frosted hollow tube.

[0056] In accordance with this first exemplary embodiment of a light therapy device, light arrays 142, 144 are positioned at a distal end 133, 135 of corresponding one of probe elements 132, 134.

[0057] Light arrays 142, 144 may be composed of one or more lighting sources (e.g., in this illustrated example, a plurality of lighting sources) that emit light in one or more of a plurality of light wavelength ranges. For example, an ultra-violet wavelength range, a visible wavelength range, which may be one of white (i.e., 380-750 nanometer (nm)) or one or more of a color light (e.g., violet - 380-435 nm; blue - 435-495 nm; cyan - 495-520; green - 420-570 nm; yellow - 570-590 nm; orange - 590-620 nm and red - 620-750 nm) and an infra-red wavelength range. The light emitted by the illustrate lighting sources may be emitted individually or in combination. Light arrays 152, 154 are positioned along a circumference of each of probe elements 132, 134 to provide a light output substantially perpendicular to the longitudinal axis of corresponding probe elements 132, 134.

[0058] In this illustrated example only two light array 152, which is represented as light arrays 152a andl52b and light array 154, which is represented as light arrays 154a and 154b are shown. However, it would be recognized that with the illustrated orthogonal positioning of light arrays 152a, 152b and 154a, 154b shown, allows for the positioning of at least four (4) light arrays 152a... 152d ( 154a-154d) adjacent distal end 133, 135 of probe elements 132, 134, respectively.

[0059] Further illustrated is light array 142 positioned adjacent distal end 133 of probe 132 and light arrays 144 positioned adjacent distal end 135 of probe 134. Light array 142 and light array 144, similar to light arrays 152a (152b) and 154a (154b) comprise at least one lighting source that may emit light in one or more of the aforementioned wavelength ranges. [0060] In the illustrated aspect of the first exemplary embodiment of light therapy device 100, although light arrays 142, 144 and 152 (i.e., 152a, 152b) and 154 (i.e., 154a, 154b) are shown external to probe elements 132, 134, in accordance with a second aspect of the first exemplary embodiment shown, light arrays 152 (i.e., 152a, 152b) and 154 (i.e., 154a, 154b) may be positioned within channels 182, 184, respectively, extending along a longitudinal axis of probe elements 132, 134, when probe elements are of a solid material, such that light arrays 152, 154 are substantially flush with an outer surface of probe elements 132, 134. In accordance with another aspect of the invention, light arrays 152a, 152b, 154a, 154b may be positioned internal to probe elements 132, 134, when probe elements 132, 134 are hollow or tubes. As would be recognized power and control lines to light arrays 142, 144, 152, 154 may be provided through channels 182, 184 when probe elements 132, 134 are of a solid material and within probe elements 132, 134 when probe elements 132, 134 are hollow. Similarly arrays 142, 144 may be internal to probe 132, 134.

[0061] In one aspect of the invention, a sleeve element (not shown) may be slid over each of probe elements 132, 134 to provide a smooth surface when probe elements (rods or tubes) 132, 134 are inserted into a body passage. The not shown sleeve element may be inserted into pass-throughs 126, 128, within cover 120. Cover 120 and the, not shown, sleeves may be removably attachable to housing 110 to provide for the sterilization of these elements after each use.

[0062] FIG. 2 illustrates a top view of the light therapy device 100 shown in FIG. 1, wherein cover 120 is shown attached to housing 110. Further illustrated are probe elements 132, 134 extending through blocking element 122, 124 via passthroughs 126, 128, respectively. [0063] In accordance with the principles of the invention, in this illustrated aspect of the invention, probe elements 132, 134 are of a length that allows the length of that portion of the probe elements 132, 134 inserted within a body passage to be increased or decreased, as needed. To allow for the re-sizing of the length of probe 132, 134 housing 110 may include a plurality of pass-throughs 262, 264 through which probe elements 132, 134 may pass. The adjustability of probe elements 132, 134 is advantageous as it enables the light emitted by one or more of the lighting sources to be in close proximity to an infected tissue.

[0064] Further illustrated are sleeve elements 232, 234 positioned over probe elements 132, 134, respectively. Sleeve elements 232, 234 provide for a smooth surface for probe elements 132, 134 (as previously discussed) as probe elements 132, 134 enter a body cavity and further prevent the lighting sources of light arrays 152, 154 from contacting the surfaces of the body cavity.

[0065] In one aspect of the invention, a filter element (referred to as an emission filter) 252, 254 is positioned on a distal end of a corresponding one of probe elements 132, 134. Emission filters 252, 254, as will be discussed, attenuate wavelengths in an undesired wavelength range while allowing wavelengths within a desired wavelength to pass so as to be captured by an image capture device (FIG. 5, ele. 510).

[0066] In one aspect of the invention, emission filters 252, 254 may be incorporated adjacent light array 142, 144. Alternatively, emission filters 252, 254 may be incorporated within sleeve elements. 232, 234.

[0067] Further illustrated are sensors 112, 114 positioned on a top surface of housing 110 and contact sensor 130 positioned on a front surface of cover 120.

[0068] FIG. 3 illustrates a front view of the light therapy device 100 shown in FIG. 1, wherein cover 120 is shown including blocking elements 122, 124, passthroughs 124, 126 and distal ends 133, 135 of probe elements 132, 134, respectively.

[0069] FIG. 4 illustrates a side view of the light therapy device 100 shown in FIG. 1, wherein cover 120 is attached to housing 110 through which probe elements 132 (not shown) within sleeve 232 passes through passage blocker 122 and cover pass-throughs 126. Further illustrated is probe 132 within sleeve 232 extending through housing pass-through 262 to allow for the adjustment of probe 132 within a nasal passage, for example.

[0070] Sleeve element 232, positioned over probel32, in one aspect of the invention, sleeve element 232 (and element 234) may comprise a clear or translucent material that allows for the distribution of light emitted by at least one light source within light array 152 (not shown).

[0071] FIG. 5 illustrates a perspective view of an exemplary configuration of light arrays 142 and 152 associated with probe 132 (which is also representative of light arrays 144, 154 associated with probe 134).

[0072] In this illustrated exemplary lighting configuration, each of light arrays 142 (144) and 152a, 152b (154a, 154b) comprise a plurality of light sources 525a, 525b, 525c and 525d, each of which comprise one or more of light emitting devices such as lasing semiconductor light emitting diodes or a non-lasing semiconductor light emitting diode.

[0073] Although light arrays 142 and 152 are shown comprised of four light sources 525a-525d it would be recognized that the number of light sources within each of light array 142 and 154 may be altered without altering the scope of the invention. Similarly, although four light arrays 152 are referred to positioned along a circumference of probe 132 (and four light arrays 154 positioned along a circumference of probe 134), it would be recognized that the number light arrays 152 (154) may also be altered without altering the scope of the invention. [0074] In this illustrated exemplary lighting configuration, the plurality of light sources 525a-525d may emit light in at least one of: an ultra-violet wavelength range, a visible wavelength range (e.g., white (i.e., 380-750 nm) or colored (e.g., violet - 380-435 nm; blue - 435-495 nm; cyan - 495-520; green - 420-570 nm; yellow - 570-590 nm; orange - 590-620 nm and red - 620-750 nm)) and an infra-red wavelength range.

[0075] Light array 142 (144) positioned on distal end 133 (135) may be composed of light sources 525a-525d that emit light in wavelength ranges similar to lighting sources 525a- 525d with regard to light array 152 (154). Alternatively, light sources 525a-525d within light array 142 (144) may emit a substantially white light to provide illumination within the body cavity, while light sources 525a-525d of light array 152 (154) may emit light in one or more wavelength ranges (e.g., UV, visible, IR) that provide for a therapeutic or beneficial effect to the body cavity.

[0076] In accordance with the principles of the invention, an image capture device 510 may be positioned on, or adjacent, distal end 133 (135) of probe 132 (134). Image capture device (e.g., camera, a CCD, etc.) may be configured to capture images of an area illuminated by the light emitted by one or more of the plurality of light sources 525a-525d within each of the light arrays 142, 144, 152, 154.

[0077] The ability to capture images of the area illuminated by the one or more of the plurality of light sources 525a-525d is advantageous as it allows for the viewing of an area subjected to the light therapy provided by light therapy device 100.

[0078] FIG. 6 illustrates an exemplary lighting configuration in accordance with the principles of the invention.

[0079] In this exemplary lighting configuration, each the illustrated light arrays 152a (154a), 152b (154b) include a plurality of light sources 525a-525d that emit light in one or more wavelength ranges as discussed. In this illustrated aspect, the light sources 525a-525d, within each of the arrays 154a-154b is not within a same position within light arrays 154a-154d. In this illustrated aspect of the invention, the light emitted by the lighting sources is distributed to different areas within the body passage.

[0080] Although FIG. 6 illustrates different light sources 525a-525d at different positions within different light arrays 154a, 154b, 154c, 154d, it would be obvious to those skilled in the art that the position of light sources 525a-525d within light arrays 152a (154a), 152b (154b), 152a (154c) and 154a (154d) may be the same or may be altered is a different manner. In addition, although the different light sources 525a-525d are illustrated, it would be obvious to those skilled in the art, that each of light sources 525a-525d in each of light arrays 152a-152d may emit a substantially same light wavelength. Alternatively, light arrays 152a-152d may comprise a light source (e.g., 525a) that emits a light of a substantially same wavelength while a second one of light arrays 152a-152d may comprise a light source (e.g., 525b) that emits light of a substantially same wavelength that is different than the light emitted by light source 525a. [0081] FIG. 7 illustrates a second exemplary embodiment of a light therapy device 700 in accordance with the principles of the invention.

[0082] In this illustrated second exemplary embodiment, light therapy device 700 comprises housing 110 and cover 120, wherein housing 110 includes a printed circuit board (not shown) that provides electrical energy received from power source (e.g., from a remote power source (not shown)) through wire 140 (or through a battery attached to housing 110), as discussed with regard to FIG. 1.

[0083] Further illustrated are housing sensor 112 (114), and contact sensor 130, which operate to control an application of a voltage to one or more of light sources, as previously discussed.

[0084] Further illustrated are extension rods/tubes/probe elements 732, 734 extending though pass-throughs 126, 128 of cover 120. Probe elements 732 and 734, similar to probe elements 132, 134, respectively, may be composed of a substantially solid, optically transparent, material to allow light to pass through unattenuated. Alternatively, probe elements 732, 734 may be substantially hollow to allow light to pass through unattenuated. [0085] In one aspect of the invention, probe elements 732, 734 may be clear or translucent or frosted to allow for a more diverse distribution of light passing through probe elements 732, 734.

[0086] In this illustrated embodiment, a distal end 733, 735 of extension rods 734, 734, respectively, comprises a hemi-spherical dome that distributes light that passes through probe elements 733, 734. Alternatively, distal end 732, 734 may be a flat surface similar to distal ends 133, 135, shown in FIG. 1.

[0087] In this illustrated aspect of the invention, positioned on distal ends 733, 735 are image capture devices 510 that are configured to capture images of the area illustrated by the light passing through probe elements 732, 734 in a manner as previously discussed.

[0088] Further illustrated are light arrays 742, 744, including a plurality of light sources 525a-525d, similar to those disclosed with regard to FIGs. 5 and 6, may emit light in one or more wavelength ranges as previously discussed. Further illustrated are plurality of objective lens 772 (i.e., 772a, 772b), 774 (i.e., 774a, 774b) that may be used to focus the light emitted by one or more of the plurality of light sources 525a-525d.

[0089] Although FIG. 7 illustrates an embodiment wherein the image capture element 510 is positioned on a distal end of a corresponding one of probe element 732, 734 and that light array 742 comprises light sources 525a-525d are positioned within probe elements 732, 734, it would be recognized that light array 142 (shown in FIG. 1) may replace the illustrated image capture device 510 and light array 742 without altering the scope of the invention. [0090] Similar to the embodiment shown in FIGs. 2-4, probe elements 732, 734 may include sleeve elements 232, 234, respectively, which provide for a smooth surface to prevent irritation when inserted into a body cavity.

[0091] In accordance with one aspect of the invention, each of sleeve elements 232, 234 includes a distal end endcap that includes an emission filter 252, 254, respectively, wherein the filter characteristics of the emission filter are, in this illustrated embodiment, molded into the illustrated endcap. Alternatively, emission filters 252, 254 may be a separate element that may be attached to a distal end of corresponding sleeve elements 252, 254. Alternatively, emission filters 252, 254 may be incorporated within sleeve elements 232, 234, respectively.

[0092] Emission filters 252, 254 operate to limit the light wavelength range collected by image capture device 510. See, for example, the discussion of determining filter characteristics regarding limiting the wavelength range of light collected by image capture device 510 found in USP 11,099,376, for example, which is assigned to the Assignee of the instant application, the contents of which are incorporated by reference, herein. That is, the filter characteristics of emission filters 252, 254 may be selected to block (i.e., attenuate below a known level) the viewing of the light emitted by the lighting sources while allowing the viewing (i.e., passage) of light generated by the interaction of the emitted light with bacterial, or other causes, of infection. According, the filter characteristics are, in part, determined by the wavelength of the emitted light and the expected wavelength of light generated by the interaction of the emitted light with bacterial, or other causes, of infection.

[0093] FIG. 8 illustrates a top view of the light therapy device 700 shown in FIG. 7 wherein cover 120 is attached to housing 110 and probe elements 732, 734 extend through cover 120 and housing 110, in a manner similar to the first embodiment of the invention disclosed in FIG. 1. The extension of probe elements 732, 734 through housing 110 allows for the adjustment , within a body (e.g., nasal) cavity of the distal end 733, 735 (see FIG. 7) of probe elements 732, 734, respectively.

[0094] Further illustrated are emission filters 252, 254 attached to a distal end of sleeve elements 232, 234. In this illustrated case, the emission filters 252, 254 are planar. However, it would be understood that the end caps housing emission filters 252, 254 may be domed shaped as shown in FIG. 7, for example.

[0095] FIG. 9 illustrates a front view of the light therapy device 700 shown in FIG. 7 wherein sensor 112 and cover sensor 130 are shown. The front view illustrated in FIG. 9 is similar to the front view shown in FIG. 3, for example.

[0096] FIG. 10 illustrates a side view, through section F-F shown in FIG. 9, of the light therapy device 700 shown in FIG. 7, wherein probe element 732 is shown positioned within sleeve 232, which includes emission filter 252, and light array 742 positioned within probe rod 732 a known distance from distal end 733

[0097] In one aspect of the invention, probe elements 732, 734 may be transparent or clear while sleeve 232 may be one of transparent to allow light emitted by at least one of light sources 525a-525d to pass through sleeve 232 or translucent to distribute light emitted by at least one of light sources 525a-525d.

[0098] FIG. 11 illustrates an expanded view of the area designated as fig. 11 in FIG. 10 illustrating light sources 525a, 525b on light array 742 and lens 772a, 772b. Lens 772a, 772b allow for the focusing of light emitted by one or more of the light sources 525a-525d. Although two lenses 772a, 772b are shown, it would be obvious to alter the number of, and/or the type of lenses, without altering the scope of the invention.

[0098] FIG. 12 illustrates an exploded perspective view of the expanded area designated as fig. 17 shown in FIG. 10, wherein light sources 525a-525d are arranged on light array 742, for example. Light sources 525a-525d are similar to the light sources described with regard to FIG.

5 and a detailed discussion of light sources 525a-525d with regard to FIG. 12 is believed would be understood by those skilled in the art by a reading of the discussion of FIG. 5.

[0100] In one aspect of the invention, one or more of lens 772a, 772b may include a filter system (referred to hereinafter as excitation filter) that is configured to limit a light wavelength range emitted by one or more of the light sources 525a-525d, as will be further discussed.

[0101] FIG. 13 illustrates a perspective view of a third exemplary embodiment of a light therapy device 1300 in accordance with the principles of the invention.

[0102] Light therapy device 1300, similar to light therapy device 100 (and 700), comprises housing 110 containing a printed circuit board (not shown) suitable for applying a voltage supplied through a power supply/control panel 1360, wherein power supply/control panel 1360 may comprise a portable power supply, such as a battery (preferably, rechargeable). [0103] Further shown is cover 120 comprising passageway blockage cups 122, 124 and corresponding passthroughs 126, 128, which are configured to allow probe elements 732, 734 to be adjustably positioned within a bodily cavity (e.g., nasal passage), as previously discussed. [0104] Further illustrated is control board 1350, actuators 1342, 1344 and light arrays 742, 744, comprising light sources 525a-525d, similar to those shown in FIG. 7, positioned on actuators 1342, 1344, .

[0105] Positioned within housing 110, control board 1350 includes tabs 1352, 1354 onto which actuators 1342, 1344 are positioned. Actuators 1342, 1344 provide a means to rotate light arrays 742, 744 about tabs 1352, 1354, respectively, so as to position at least one of the light sources 525a-525d along a center line of probe elements 732, 734.

[0106] Further illustrated are lens 772, 774 associated with corresponding ones of light arrays 742, 744. Lens 772, 774 may include filtering characteristics (i.e., forming excitation filters) that limit the light wavelength band of the light emitted by at least one of the light sources 525a-525d.

[0107] Lighting device 1300 further includes probe elements, in this case 732, 734 and sleeve elements 232, 234, which are similar to those discussed with regard to FIG. 7. [0108] FIG. 14 illustrates a top view of the light therapy device 1300 shown in FIG. 13, comprising housing 110 including sensor 112, 114 and cover 120 including contact sensor 130, which are similar to those element discussed with regard to FIGs. 1 and 7. Further illustrated are probe elements 732, 734, within sleeve elements 232, 234, extending through cover passthroughs 126, 128. In this illustrated example, probe elements 732, 734 are of a fixed length. Further illustrated are emission filters 252, 254 positioned on a distal end of sleeve elements 232, 234.

[0109] Further illustrated, along a top surface of housing 110, are actuators 1342, 1344, which allow for the rotation of light arrays 742, 744, respectively, within housing 110.

[0110] FIG. 15 illustrates a front view of the light therapy device 1300 shown in FIG. 13, wherein light therapy device 1300 comprises cover 120 including contact sensor 130 and cover passthroughs 126, 128 into which probe elements 732,734, are inserted.

[0111] Further illustrated are actuators 1342, 1344 configured to rotate light arrays 742, 744, respectively, to position at least one of light sources 525a-525d along a central axis of probe elements 732, 734, respectively.

[0112] FIG. 16 illustrates a side view, through section C-C shown in FIG. 15, of the light therapy device 1300 shown in FIG. 13, wherein probe element 732 extends through cover passthrough 126, and one of the light sources 525a-525d of light array 742 is positioned along a central axis of probe element 732. Further illustrated is image capture device 510 positioned on a distal end of probe element 732 and filter 252 positioned on a distal end of sleeve element 232.

[0113] FIG. 17 illustrates an expanded view of the area designated as fig. 17 in FIG. 16, wherein probe element 732 comprising lens 772 (i.e., 772a, 772b) and one of the pluralities of light sources 525a-525d is positioned along a center axis of probe element 732. In accordance with the principles of the invention, light emitted by the at least one light source 525a-525d positioned along a center axis of probe element 732 is transmitted through probe element 732 to provide light to a distal end of probe element 732. As previously discussed, probe elements 732, 734 may be of a clear or translucent solid material or hollow.

[0114] As previously discussed sleeve 232 may be clear or translucent, wherein an translucent sleeve allows for the dispersion of the light emitted by the at least one light source positioned along a center axis of, in this case, probe element 732.

[0115] FIG. 18 illustrates a front view of control board 1350 wherein light arrays 742, 744 are positioned on actuators 1342, 1344, respectively and are rotatable to place at least one of the lighting sources 525a-525d along a center axis of corresponding ones of probe elements 732, 734 to enable the light of the positioned light source to be emitted through probe elements 732, 734.

[0116] FIG. 19 illustrates a perspective view of another exemplary embodiment of probe elements 132 (134), and 732 (734) in accordance with the principles of the invention. [0117] Although the illustrated embodiment is described with regard to probe elements 732, 734, it would also be understood that the exemplary embodiment disclosed is also applicable to probe elements 132 (134) .

[0118] In this exemplary embodiment, probe elements 732, 734 comprise a hollow tube element 1902, 1904, respectively, into which may be inserted or placed optical fiber bundles 1912, 1914, respectively. Optical fiber bundles 1912, 1914 comprise a plurality of fiber optical cables 1910 arranged about a central core element 1915. Central core element 1915 may comprise one of an optical clear medium, wherein images captured by the image capture device 510 may be transmitted to an optica l/electrica I circuitry or an electrical conduit, where the electrical representations (e.g., pixels) of the image captured by the image capture device is transmitted to an electrical circuitry for further processing.

[0119] Further illustrated are light arrays 742, 744 positioned at a proximal end 1932, 1934 of probe element 732, 734, respectively. Each of light arrays 742, 744 include light sources 525a-525d, as previously discussed.

[0120] In accordance with the principles of the invention, light emitted by at least one of the light sources 525a-525d associated with light arrays 742, 744, enters a proximal end 1932, 1934 of selected ones of the illustrated fiber optic cables 1910 (i.e., light bearing cables, 1910a) within bundles 1912, 1914, respectively, and is transmitted to corresponding distal ends 1942, 1944 of the light bearing fiber optic cables 1910a within bundles 1912, 1914.

[0121] Further illustrated is image capture device 510 positioned on the distal end 1942, 1944 of fiber optic cable bundle 1912, 1914, respectively to capture images of an area illuminated by the light emitted by the at least one light source 525a-525d. Although two image capture devices are illustrated, it would be recognized that a single image capture device may be utilized and may be associated with either fiber bundle 1912 or fiber bundle 1914.

[0122] In one aspect of the invention, the electrical representations of the images (i.e., pixels) captured by image capture device 510 may be transmitted through selected ones of fiber optic cables 1910 (i.e., image bearing cables 1910b) within bundles 1912 and/or 1914 to light array 742 and/or 744, which includes electrical circuitry suitable for storing on a storage device or transmitting to a storage device the captured images or transmitting to a viewing device for viewing the captured images.

[0123] Further illustrated is sleeve elements 232, 234 positioned over hollow rod elements, 1904. Sleeve elements 232, 234 may further incorporate a filter element 252, 254 on a distal end of sleeve elements 232, 234, as previously discussed.

[0124] Although hollow rod elements 1902 (1904) and sleeve element 232(234) are shown as different elements, it would be recognized that hollow rod elements (1904) and sleeve 232 (234) may be incorporated as a single element, wherein emission filter 252, 254 may be incorporated on a distal end of hollow rod elements 1902, 1904.

[0125] FIG. 20 illustrates a front view of the first exemplary embodiment of fiber optic bundle 1912 (1914) shown in FIG. 19, wherein a plurality of light bearing fiber optic cables 1910a are arranged concentrically about centrally located core (or cable) 1915 that transfers pixels information from the image capture device 510 to an electrical circuit for further processing. 124.

[0126] FIG. 21 illustrates an expanded perspective view of the area designated as fig. 21 in FIG. 19 showing distal end 2110 of light bearing fiber cables 1910a modified to cause light transmitted in the light bearing fiber optic cables 1910a to be emitted in a direction substantially perpendicular to a longitudinal axis of optical bundle 1912.

[0127] In the illustrated aspect of the invention, distal end 2110 of the light bearing optical fibers 1910a include an angle with respect to a longitudinal axis of the fiber bundle 1910a, which enables light within fibers 1910a to be emitted substantially perpendicular to a longitudinal axis of the fiber optic cable.

[0128] Further illustrated is image capture device 510 positioned on a distal end of optical fiber 1910, wherein fiber 1910b provides means to transmit images captured by image capture device 510 to array 732 (734), where the images may be further transmitted to a collection device that allows for the viewing, in real-time, of the captured images.

[0129] FIG. 22 illustrates a fourth exemplary embodiment of a light therapy device in accordance with the principles of the invention.

[0130] In this exemplary embodiment, which is similar to the embodiment shown in FIG. 7, comprises a single probe element 732 that provides light therapy to a body cavity (e.g., a single nasal cavity, an ear canal, etc.).

[0131] A description of the elements and the operation of the light therapy device illustrated in FIG. 22 would be understood by those skilled in the art from a reading of comparable elements disclosed, herein (see FIG. 7, for example), and a detailed description of the elements and operation of the light therapy device 2200 shown in FIG. 22 is not believed necessary.

[0132] Returning to FIG. 7, emission filter 252 (254) positioned before image capture device 510 is configured to limit the wavelengths passed by emission filter 252 (254) to a wavelength range that excludes or reduces in magnitude wavelengths that are emitted by a corresponding one of light sources 525a-525d. Specifically, emission filter 252 (254) is formulated using material that absorb or reflect light emitted by selected ones of light sources 525a-525d to a level that is neither harmful to the user's eyes or interferes with the viewing (or capturing) of light at a different wavelength or in a different wavelength range. In one aspect of the invention, emission filters 252 may comprise a high pass filter that attenuates light in a first wavelength range (e.g., emitted light of one or more of light sources 525a-525d) to a known magnitude while allowing light in a second (higher) wavelength range to pass substantially unattended, wherein said known magnitude is below known safety limits associated with the viewing of the emitted light. In a second aspect of the invention, emission filters 242 may comprise a bandpass filter that attenuates light in at least a first wavelength range (e.g., emitted light of one or more light sources 525a-525d) while allowing light within a second wavelength range, wherein the second wavelength range is based on the wavelength of the emitted light and the wavelength of the expected light to be generated by an interaction of the emitted light with an object illuminated by the emitted light.

[0133] In addition, it would be recognized that the size (i.e., length or width) of probe element 132 or 732, may be adjusted based on the bodily cavity into which the disclosed devices may be inserted. As shown in FIG. 8, the length of probe element 732 may be increased to allow probe elements 132 or 732 to be positioned deeper into the body cavity. Alternatively, the length of probe element 132 (732) may be fixed and the insertion into a body cavity may be limited to the fixed length of probe element 132 (732). Similarly, probe element 132 (732) may be interchangeable such that the width (i.e., the cross-sectional diameter) of probe element 132 (732) may be increased or decreased dependent upon the size of the body cavity into which the devices disclosed, herein, may be inserted.

[0134] In an alternative embodiment, the probe elements 132 (732) may be of a fixed width and the sleeve elements 234 (234) , shown in FIG. 2, that covers the light bearing elements of probe elements 132 (732) may be of width sized based on the specific body cavity into which the devices disclosed, herein, may be inserted. That is, a device, such as shown in FIGs. 1, 7, and 13 (and 22) inserted into a nose cavity may be sized based on the expected nasal cavity diameter (e.g., male, female, adult, child). Or a device as shown in FIG. 22, for example, inserted into the vaginal cavity may be of a greater diameter. Similarly, the length of sleeve 232 (234) may be sized to allow for an increase in the length of probe element 132 (732) contained therein.

[0135] In still a further aspect of the invention, the probe element 132 (732) or sleeve element 232 may be shaped to accommodate the specific body cavity into which the devices disclosed, herein, may be inserted. For example, and as previously discussed, the probe element 132 (732) or sleeve 232 may be of a pliable material that may be flexed (and retained) into a shape to accommodate the body cavity.

[0136] In accordance with one aspect of the invention, sleeve element 232 (234) may be removably attachable to cover element 120 by one or more of a snap fit, screw thread, friction fit, a bayonet connection, and clamp connection. For example, cover 120 may include a clamp or jaw-like mechanism that may engage a distal end of sleeve element 232 (234) to retain sleeve element 232 (234) attached to cover 120. Furthermore, opening of the clamp or jaw-like mechanism releases sleeve element 232 (234) from its attachment to cover 120. In this case, sleeve element 232 (234) may comprise a disposable cover that allows for the usage of device 100, for example, to be utilized for multiple patients.

[0137] Similarly, with regard to probe element 732 (734) as shown in FIG. 19, for example, sleeve element 232 and/or hollow rod element 1902 may be removably attachable to cover 120 to allow for the usage of device 700, for example, with multiple patients.

[0138] In summary, a light therapy device is disclosed that is suitable for insertion into a body cavity, such as nasal passage, which provides for diagnostic and treatment of bacteria within the body cavity, wherein the device includes a plurality of lighting sources arranged in light arrays that emit light at a distal end of the probe elements or though the probe elements inserted into the body cavity. The emitted light is further controlled by a combination of switches that ensure the device is appropriately positioned and the user is ready to administer the light treatment.

[0139] Although the invention disclosed herein discusses specific wavelengths that are produced with currently available LEDs (i.e., non-lasing light emitting diodes and laser diodes), it would be recognized that the specific wavelengths absorbed and/or reflected may be changed and/or added to without altering the scope of the invention. In addition, it would be known in the art that the specific wavelengths discussed, herein, represent a band of wavelengths centered on the wavelength values presented herein to account for divergence of the wavelength generated by the LED during the generation of the light and/or the operation of the LED, wherein the light generated is represented as a nominal value.

[0140] The invention has been described with reference to specific embodiments. One of ordinary skill in the art, however, appreciates that various modifications and changes can be made without departing from the scope of the invention as set forth in the claims. Accordingly, the specification is to be regarded in an illustrative manner, rather than with a restrictive view, and all such modifications are intended to be included within the scope of the invention.

[0141] Benefits, other advantages, and solutions to problems have been described above regarding specific embodiments. The benefits, advantages, and solutions to problems, and any element(s) that may cause any benefits, advantages, or solutions to occur or become more pronounced, are not to be construed as a critical, required, or an essential feature or element of any or all of the claims

Claims

What is claimed is:

1. A light therapy device comprising: a housing comprising: a turn-on switch configured to: generate a first indication; and an electronic circuit configured to: receive a voltage; a cover removably attachable to said housing, said cover comprising: at least one cover passthrough; and at least one contact sensor configured to: generate a second indication based on a determination of said light therapy device being properly positioned; a probe element extending through a corresponding one of each of said at least one cover passthrough, said probe element comprising at least one of: an solid material and a hollow tube material; and a plurality of lighting sources, wherein said electronic circuit is configured to: distribute said voltage to selected ones of said plurality of lighting sources based on concurrent reception of said first indication and said second indication.

2. The light therapy device of claim 1, wherein said solid material comprises one of: an optically clear material, a translucent material and a frosted material.

3. The light therapy device of claim 1, wherein said plurality of lighting sources are arranged on a distal end of a corresponding one of said at least one probe element.

4. The light therapy device of claim 3, wherein said plurality of lighting sources are arranged on an exterior surface of a corresponding one of said at least one probe element.

5. The light therapy device of claim 3, wherein said plurality of lighting sources are arranged within channels within a corresponding one of said at least one probe element.

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6. The light therapy device of claim 1, wherein said plurality of lighting sources are arranged within said at least one probe element a known distal from a distal end of a corresponding one of said at least probe element.

6. The light therapy device of claim 1, wherein said plurality of lighting sources are arranged on a rotatable wheel positioned at a distal end of a corresponding one of said at least one probe element wherein at least one of said plurality of lighting sources is positioned along a center axis of a corresponding one of said at least one probe element.

7. The light therapy device of claim 6, comprising: at least one lens positioned between selected ones of said plurality of lighting sources and a distal end of a corresponding one of said at least one probe element.

8. The light therapy device of claim 1 comprising: a sleeve, removably attachable to a corresponding one of said at least one probe element, wherein said sleeve encapsulates at least a distal end of said corresponding one of said at least one probe element.

9. The light therapy device of claim 8, wherein said sleeve comprises a filter.

10. The light therapy device of claim 9, wherein said filter is one of: attached to said distal end of said sleeve and molding into said distal end of said sleeve.

11. The light therapy device of claim 1, wherein said plurality of lighting sources emit light in at least one of: an ultra-violet wavelength range, a visible wavelength range and an infra-red wavelength range.

12. The light therapy device of claim 1, comprising: an image capture device positioned on a distal end of at least one of said at least one probe element, said image capture device configured to: capture images illuminated by light emitted by said at least one of said plurality of lighting sources.

13. The light therapy device of claim 1, wherein solid material comprises: a plurality of optical clear fiber elements arranged about a central core, said central core configured to: transmit electrical representation of said images to said electronic circuit.

14. The light therapy device of claim 13, wherein a distal end of said selected ones of said optically clear fiber elements comprising said first bundle are shaped to emit light substantially perpendicular to a longitudinal axis of said first bundle.

15. The light therapy device of claim 1 further comprising: a power source, said power source being one of: remote from said housing and attached to said housing.

16. The light therapy device of claim 1, wherein said contact sensor is one of: a contact switch, a proximity switch, and a heat sensor.

17. The light therapy device of claim 1, wherein said at least one probe element is one of: a fixed with respect to a corresponding one of said at least one cover passthrough and adjustable with respect to a corresponding one of said at least one cover passthrough.

18. The light therapy device of claim 10, wherein said filter is configured to: attenuate wavelengths of light emitted by said plurality of lighting sources below a known magnitude.

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