WO2023036112A1 - Appareil d'administration de médicament par voie rectale - Google Patents

Appareil d'administration de médicament par voie rectale Download PDF

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Publication number
WO2023036112A1
WO2023036112A1 PCT/CN2022/117206 CN2022117206W WO2023036112A1 WO 2023036112 A1 WO2023036112 A1 WO 2023036112A1 CN 2022117206 W CN2022117206 W CN 2022117206W WO 2023036112 A1 WO2023036112 A1 WO 2023036112A1
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WO
WIPO (PCT)
Prior art keywords
shaped
drug
rectal
drug delivery
delivery device
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Application number
PCT/CN2022/117206
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English (en)
Chinese (zh)
Inventor
董东生
宋玲玲
Original Assignee
浙江百获健康科技有限公司
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Publication of WO2023036112A1 publication Critical patent/WO2023036112A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A—HUMAN NECESSITIES
    • A47—FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
    • A47K—SANITARY EQUIPMENT NOT OTHERWISE PROVIDED FOR; TOILET ACCESSORIES
    • A47K7/00—Body washing or cleaning implements
    • A47K7/08—Devices or hand implements for cleaning the buttocks
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H21/00—Massage devices for cavities of the body, e.g. nose, ears and anus ; Vibration or percussion related aspects A61H23/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M3/00—Medical syringes, e.g. enemata; Irrigators
    • A61M3/02—Enemata; Irrigators
    • A61M3/0279—Cannula; Nozzles; Tips; their connection means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2201/00—Characteristics of apparatus not provided for in the preceding codes
    • A61H2201/10—Characteristics of apparatus not provided for in the preceding codes with further special therapeutic means, e.g. electrotherapy, magneto therapy or radiation therapy, chromo therapy, infrared or ultraviolet therapy
    • A61H2201/105—Characteristics of apparatus not provided for in the preceding codes with further special therapeutic means, e.g. electrotherapy, magneto therapy or radiation therapy, chromo therapy, infrared or ultraviolet therapy with means for delivering media, e.g. drugs or cosmetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/10—Trunk
    • A61M2210/1042—Alimentary tract
    • A61M2210/1067—Anus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Definitions

  • the invention relates to a rectal drug delivery device and belongs to the technical field of medical instruments.
  • Rectal administration of lubricating, stimulant drugs is a common means of coping with constipation; one of the most typical rectal delivery devices is Kaiselu.
  • the traditional Kaisailu consists of a medicine storage bottle and a drug injection tube connected with the medicine storage bottle. When in use, insert the medicine injection tube into the rectum through the anus of the human body, squeeze the medicine storage bottle, and the medicine enters the rectum through the opening of the injection tube and softens. Stool, lubricates the rectal wall, stimulates the mucous membrane and induces the defecation reflex.
  • the anal sinus at the end of the human rectum is located on the dentate line, also known as the anal recess, which opens upwards in a funnel shape, and usually has 6 to 8.
  • the dentate line also known as the anal recess
  • the depression of the anal sinus is opened, the inner wall of the anal sinus is in contact with feces.
  • Increased friction between feces and the wall of the anal canal affects the smooth discharge of feces, and the anatomical characteristics of the anal sinus make it easy for feces and foreign bodies to accumulate in it. Once infected by bacteria, the inflammatory substances are difficult to drain smoothly.
  • the traditional Kaisailu drug injection tube is a smooth tube with no obvious change in inner diameter, which is not enough to exert an effect on the expansion of the anorectal wall. Stimulation; For patients with diarrhea, the thin and soft feces retained in the rectal mucosa and anal sinus are not easy to discharge, and the bacteria, viruses, parasites, etc. in them are more likely to cause inflammation and stimulation, resulting in excessive bacterial reproduction, intestinal transport function defects, Intestinal motility disorder, accompanied by tenesmus, abdominal pain and other symptoms, the smooth thin tube of the traditional Kaiselu into the rectum cannot effectively remove the retained feces, etc. from the body.
  • Rectal drug delivery device that removes secretions, foreign bodies, etc. from the body.
  • the present invention provides a rectal drug delivery device that can effectively wipe away feces, inflammatory secretions, foreign matter, etc. remaining on the anal sinus and rectal mucosa and remove them from the body.
  • the rectal drug delivery device includes a rod-shaped part with a top end and a bottom end, an auxiliary part and a drug channel for delivering medicine.
  • a rod-shaped part with a top end and a bottom end, an auxiliary part and a drug channel for delivering medicine.
  • On top of the part at least the auxiliary part that enters the rectum is made of a material that is less rigid than the rod-shaped part, and the auxiliary part is provided with a dimple that can hold the drug and/or fecal matter, and the dimple is provided with at least one opening;
  • the rod-shaped Components, auxiliary components, each component can be composed of one part or multiple parts.
  • the dimple may be a simple depression, or a bag shape with an opening formed by partially covering the depression, or a bag shape formed by partially covering the non-depressed area of the auxiliary component.
  • the auxiliary parts are provided with openings in the same direction as and/or intersecting the longitudinal axis of the rod-shaped part, including line-shaped, drop-shaped, scatter-shaped, jagged, beaded, and ring-shaped , wrinkled, terraced, bag-shaped, continuous spiral lacuna, including at least one kind of lacuna.
  • the outer surface of the auxiliary parts is also equipped with rope-shaped, nail-shaped, boss-shaped, hook-shaped, drop-shaped, At least one kind of protrusions including striated, scatter-like, jagged, beaded, wrinkled, terraced, burr-like, and continuous spiral protrusions.
  • multiple protrusions can be arranged around the circumference; preferably, the ends of the protrusions face upward, that is, towards the top of the auxiliary component, so that the anal sinus and nearby mucous membranes can be wiped to the greatest extent.
  • the protrusions of the above shapes may also be two types of protrusions with their ends pointing up and their ends facing down, arranged in a staggered up and down and/or other staggered manner.
  • a dimple is provided at the upper position of the protruding body with the free end upward and/or a dimple is provided at the lower position of the protruding body with the free end downward.
  • the dimples arranged above the protruding body with the free end upward and/or below the protruding body with the free end downward can accommodate feces and inflammatory secretions that are scraped off by the protruding body and remain on the anal sinus and rectal mucosa. It can more effectively remove feces, inflammatory secretions, foreign bodies, etc.
  • the outer surface of the auxiliary component is provided with a protrusion conforming to the anal sinus, and the dimple is arranged on the protrusion conforming to the anal sinus;
  • the protrusion conforming to the anal sinus means that it can be inserted into and Fully filling the interior of the hollow anal sinus makes it easier to scrape off the residual feces, inflammatory secretions, foreign bodies, etc. in the anal sinus, and promptly accommodate them in the lacuna and move them out of the body.
  • the medicine channel is arranged between the outer surface of the rod-shaped part and the inner surface of the auxiliary part, the top of the auxiliary part covers the top of the rod-shaped part, and the drug outlet of the medicine channel is arranged on the auxiliary part.
  • the drug storage part for storing drugs.
  • the drug outlet of the drug storage part is connected with the drug inlet of the drug channel; the drug storage part can store liquid water or drug solution, even Paste and gel have the functions of lubricating, antibacterial, cleaning, and promoting wound healing.
  • the bottom end area of the rod-shaped part and/or the bottom end area of the auxiliary part is provided with a radially extending part, which is pressed against the anus during use, and the device above the radially extending part can be into the rectum.
  • the outer surface of the device is provided with scale lines that increase in value from the top end of the auxiliary part to the bottom end of the auxiliary part.
  • the auxiliary parts of the present invention are provided with pits that can accommodate drugs and/or fecal matter and protrusions that can penetrate into the anal sinus and stimulate the rectal mucosa. During use, feces, inflammatory secretions, foreign matter, etc.
  • anal cushion area such as tension sensory receptor Pacinian corpuscle, friction sensory receptor Genital corpuscle, pressure sensory receptor Golgi-Mazzoni body, promote defecation; help to eliminate constipation caused by anal sinus inflammation, help prevent and treat anal sinusitis after diarrhea, help prevent, care and treat anorectal diseases such as hemorrhoids and anal fissures, and help Help patients with diarrhea to clean up the feces, inflammatory secretions, foreign bodies, etc. inside the anal sinus and on the rectal mucosa in time to avoid blocking the opening of the anal glands and causing inflammation.
  • Pacinian corpuscle friction sensory receptor Genital corpuscle
  • Golgi-Mazzoni body pressure sensory receptor Golgi-Mazzoni body
  • the drug channel of the present invention is set between the outer surface of the rod-shaped part and the inner surface of the auxiliary part and/or on the auxiliary part.
  • the diameter of the drug channel is smaller than that of the existing drug delivery channels such as Kaisailu, and the drug residue is less , the drug in the drug storage part can fully act on the anal sinus and rectal mucosa of the human body; and the drug outlet of the drug channel is closer to the anal canal and rectal mucosa. Mucous membrane, it is easier to remove feces, inflammatory secretions, foreign bodies, etc.
  • the weaker area on the auxiliary part will undergo wave-like changes due to impact pressure expansion, and local swelling It can also stimulate the anal canal and rectal mucosa, stimulate the sense of fullness and reflex in the rectum, and promote defecation.
  • Figure 1A Schematic diagram of the anatomy of the anal canal and anal sinus
  • Figure 1B Cross-sectional view of the anal sinus
  • Figure 1C Schematic diagram of traditional products acting on the anal sinus
  • FIG. 1D a schematic diagram of Embodiment 1 of the present invention.
  • Figure 1E A schematic diagram of the action of Example 1 of the present invention on the anal sinus
  • Figure 1F a schematic diagram of Example 1 of the present invention entering the rectum
  • Fig. 2 schematic diagram of Embodiment 2 of the present invention
  • Fig. 3 the schematic diagram of embodiment 3 of the present invention.
  • Fig. 4A a schematic diagram of secondary dimples provided in Example 4 of the present invention.
  • Figure 4B a schematic diagram of a protrusion provided in Embodiment 4 of the present invention.
  • Figure 5 a schematic diagram of Embodiment 5 of the present invention.
  • Figure 6 a schematic diagram of Embodiment 6 of the present invention.
  • embodiment 1 of the present invention comprises: rod-shaped part 1, auxiliary part 2 and the drug channel 3 that is used to deliver medicine, and drug channel 3 is provided with at least one drug inlet 31 and at least one A drug outlet 32, the auxiliary part 2 fits on the rod-shaped part 1, at least the hardness of the material of the auxiliary part 2 that enters the rectum is lower than that of the rod-shaped part 1, and the auxiliary part 2 is provided with the opening direction and the rod-shaped part.
  • Dimples 20 that have the same and/or intersecting longitudinal axes, including line-shaped, drop-shaped, scatter-shaped, jagged, beaded, ring-shaped, wrinkled, terraced, bag-shaped, and continuous spiral-shaped dimples 20 At least one dimple 20 for containing medicine and/or fecal matter.
  • the dimple 20 is provided with at least one opening 201.
  • the dimple 20 can be a simple depression, or a pocket with an opening formed by partially covering the depression, It can also be a bag shape formed by partially covering the non-recessed area of the auxiliary part;
  • the auxiliary part 2 can be made of medical-grade thermoplastic elastomer TPE material or silicone rubber material in one piece, which not only has good biocompatibility, but also has good texture Softer and more comfortable in contact with the human body;
  • rod-shaped parts and auxiliary parts, each part can be composed of one part or multiple parts; in order to facilitate the insertion of the device into the rectum, the length of the device inserted into the rectum is limited, and the rod
  • the region of the bottom end 14 of the shaped part and/or the region of the bottom end 24 of the auxiliary part is provided with a radially extending part 24a, which abuts against the anus during use, and the part of the device above the radially extending part 24a can enter the rectum;
  • the scale line S whose value increases from the
  • the drug storage part 4 is fan-shaped and made by blow molding , the drug storage part 4 has a drug storage cavity with a certain volume, internally stores rectal lubricants such as glycerin, paraffin oil, and mannitol, and can also be ointment, emulsion, etc., which have the functions of lubricating the anorectal wall, softening feces, promoting defecation, antibacterial, anesthesia, and supplementing probiotics.
  • rectal lubricants such as glycerin, paraffin oil, and mannitol
  • rectal lubricants such as glycerin, paraffin oil, and mannitol
  • ointment, emulsion, etc. which have the functions of lubricating the anorectal wall, softening feces, promoting defecation, antibacterial, anesthesia, and supplementing probiotics.
  • the outer surface 21 of the auxiliary component is also equipped with cord-shaped, nail-shaped, boss-shaped, hook-shaped, At least one protrusion 211 including drop-shaped, striated, scatter-shaped, jagged, beaded, wrinkled, terraced, burr-shaped, and continuous spiral protrusions 211; as shown in Figures 1D-1F , in this embodiment, the protrusions 211 and the dimples 20 are both hook-shaped, and the dimples 20 are arranged between two adjacent protrusions 211.
  • the lacuna 20 can also accommodate a certain amount of lubricating, cleaning, and antibacterial drugs.
  • This device stimulates the anal canal and rectal mucosa, stimulates the sense of fullness and inflation reflex of the rectum, and at the same time can effectively remove feces and inflammatory secretions. , foreign matter, etc., are fully wiped and removed.
  • a dimple 20 is provided above the protruding body 211a with the free end upward, and a dimple 20 is provided at the lower position of the protruding body 211b with the free end downward.
  • the dimples arranged above the protruding body 211a with the free end upward and/or below the protruding body 211b with the free end downward can accommodate the anal Feces, inflammatory secretions, and foreign objects in the sinus and on the rectal mucosa, and the feces or foreign objects scraped off in the anal sinus enter the interior of the lacuna 20 and are taken out of the body together with the device, which is more effective and fully wiped to remove feces and inflammation secretions, foreign bodies, etc.
  • the dimple 20 is a pocket formed by partially covering the non-recessed area of the auxiliary part, which is easy to be molded.
  • the opening 201 faces the top end 23 of the auxiliary part and the opening 201 faces the auxiliary part.
  • the dimples 20 at the bottom end 24 are arranged in sequence.
  • the dimples 20 can not only accommodate feces, inflammatory secretions, foreign objects, etc. that are wiped away when the device moves upward or downward, but also can closely contact and stimulate the anal canal and rectal mucosa to promote defecation .
  • Example 1 The difference from Example 1 is that, as shown in Figure 4A, there are secondary dimples 201 in the dimple 20, and as shown in Figure 4B, there are a plurality of columnar protrusions 202 in the dimple 20, and the thin and soft feces of patients with diarrhea tend to stay in the Bacteria and viruses carried inside the anal sinus or on the rectal mucosa are likely to cause intestinal infection and inflammation, and the secondary lacuna 201 and/or protrusion 202 can ensure that the feces and inflammation contained in the lacuna 20 are wiped and removed. Secretion, foreign matter, etc.
  • Embodiment 1 The difference from Embodiment 1 is that, as shown in Figure 5, the outer surface 21 of the auxiliary part is provided with a protrusion 212 conforming to the anal sinus, and the dimple 20 is arranged on the protrusion 212 conforming to the anal sinus, and the protrusion 212 conforming to the anal sinus
  • the conformable protrusion 212 means that it can penetrate into and fully fill the hollow anal sinus, and the feces or foreign objects scraped off in the anal sinus enter the interior of the lacuna 20 and are taken out of the body together with the device, making it easier to displace the anal sinus Scrape off the residual feces, inflammatory secretions, foreign bodies, etc. in the anal sinus, more effectively clean the anal sinus, stimulate the defecation receptors at the bottom of the anal sinus, and promote defecation.
  • Embodiment 6 is a diagrammatic representation of Embodiment 6
  • the drug passage 3 is arranged between the outer surface 11 of the rod-shaped part and the inner surface 22 of the auxiliary part, specifically formed by a channel-like gap between the two, and the top end 23 of the auxiliary part covers
  • the top 13 of the rod-shaped part and the drug outlet 32 of the drug passage 3 are arranged on the auxiliary part 2, the diameter of the drug channel is small, the drug residue is small, and the drug in the drug storage part can fully act on the anal sinus and rectal mucosa of the human body; and
  • the drug outlet of the drug channel is closer to the anal canal and rectal mucosa.
  • the drug When the drug is extruded, it has a certain flushing speed, which can more effectively flush the anal canal and rectal mucosa, and wash away feces, inflammatory secretions, foreign objects, etc. remaining in the anal sinus ;
  • the weaker area on the auxiliary part expands in waves due to the impact pressure, and the local expansion can stimulate the anal canal and rectal mucosa, stimulate the sense of fullness and fullness reflex of the rectum, and promote defecation .
  • Various schemes of the present invention can repeatedly enter and exit the anus when used, increasing the frequency of wiping can play a more sufficient wiping and cleaning effect; wiping and stimulating the anal sinus A3 in patients with constipation can promote gland secretion, exert self-lubricating effect, and can stimulate defecation reflex ; The thin soft feces left in the anal sinus and on the rectal mucosa after defecation in patients with diarrhea are wiped and removed, and then accommodated in the lacuna and removed from the body together with the device, similar to brushing teeth as a routine oral cleaning, even if there is no anorectal disease. Wipe after defecation every day , Cleaning the anal sinus and rectal mucosa will also play a role in preventing anorectal diseases such as anal sinusitis.

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  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Otolaryngology (AREA)
  • Reproductive Health (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rehabilitation Therapy (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

L'invention concerne un appareil d'administration de médicament par voie rectale, comprenant un élément en forme de tige (1) ayant une extrémité supérieure et une extrémité inférieure, un élément auxiliaire (2), et un canal de médicament (3) utilisé pour administrer un médicament, le canal de médicament (3) étant pourvu d'au moins une entrée de médicament (31) et d'au moins une sortie de médicament (32). L'élément auxiliaire (2) est ajusté de manière conforme au-dessus de l'élément en forme de tige (1). Le matériau de l'élément auxiliaire (2) pénétrant au moins dans le rectum présente une dureté inférieure à celle de l'élément en forme de tige (1), l'élément auxiliaire (2) est pourvu d'encoches (20) pouvant contenir un médicament et/ou une substance fécale, et chaque encoche (20) est pourvue d'au moins une ouverture (201).
PCT/CN2022/117206 2021-09-07 2022-09-06 Appareil d'administration de médicament par voie rectale WO2023036112A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN202111044160.2 2021-09-07
CN202111044160.2A CN113599682A (zh) 2021-09-07 2021-09-07 直肠给药装置

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WO2023036112A1 true WO2023036112A1 (fr) 2023-03-16

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WO (1) WO2023036112A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113599682A (zh) * 2021-09-07 2021-11-05 浙江百获健康科技有限公司 直肠给药装置
CN113599681A (zh) * 2021-09-07 2021-11-05 浙江百获健康科技有限公司 一种直肠给药装置
CN115737959A (zh) * 2022-08-06 2023-03-07 浙江百获健康科技有限公司 作用于肛管的装置

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN201414996Y (zh) * 2009-03-13 2010-03-03 赵学 一种肛部疾病治疗及肛部保健装置
US20110054413A1 (en) * 2008-05-06 2011-03-03 Roemhild Ludwig Pin for hygienic and/or medical use in the anal region
CN104721947A (zh) * 2013-12-24 2015-06-24 北京万生人和科技有限公司 一种直肠内给药装置
CN105688326A (zh) * 2014-11-27 2016-06-22 北京万生人和科技有限公司 一种带止流阀直肠给药装置
CN108888857A (zh) * 2018-05-26 2018-11-27 北京仰生恒泰科技有限责任公司 一种作用于肛窦的装置
CN113599682A (zh) * 2021-09-07 2021-11-05 浙江百获健康科技有限公司 直肠给药装置
CN216061656U (zh) * 2021-09-07 2022-03-18 浙江百获健康科技有限公司 直肠给药装置

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110054413A1 (en) * 2008-05-06 2011-03-03 Roemhild Ludwig Pin for hygienic and/or medical use in the anal region
CN201414996Y (zh) * 2009-03-13 2010-03-03 赵学 一种肛部疾病治疗及肛部保健装置
CN104721947A (zh) * 2013-12-24 2015-06-24 北京万生人和科技有限公司 一种直肠内给药装置
CN105688326A (zh) * 2014-11-27 2016-06-22 北京万生人和科技有限公司 一种带止流阀直肠给药装置
CN108888857A (zh) * 2018-05-26 2018-11-27 北京仰生恒泰科技有限责任公司 一种作用于肛窦的装置
CN113599682A (zh) * 2021-09-07 2021-11-05 浙江百获健康科技有限公司 直肠给药装置
CN216061656U (zh) * 2021-09-07 2022-03-18 浙江百获健康科技有限公司 直肠给药装置

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