WO2023000771A1 - 一种基于超声下瞳孔变化的麻醉深度监测系统及检测方法 - Google Patents

一种基于超声下瞳孔变化的麻醉深度监测系统及检测方法 Download PDF

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WO2023000771A1
WO2023000771A1 PCT/CN2022/091607 CN2022091607W WO2023000771A1 WO 2023000771 A1 WO2023000771 A1 WO 2023000771A1 CN 2022091607 W CN2022091607 W CN 2022091607W WO 2023000771 A1 WO2023000771 A1 WO 2023000771A1
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pupil
ultrasound
ultrasonic
monitoring system
probes
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PCT/CN2022/091607
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English (en)
French (fr)
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王琛
邓岩军
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苏州科技城医院
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Priority to US18/251,508 priority Critical patent/US20240023887A1/en
Publication of WO2023000771A1 publication Critical patent/WO2023000771A1/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4821—Determining level or depth of anaesthesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/11—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for measuring interpupillary distance or diameter of pupils
    • A61B3/112—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for measuring interpupillary distance or diameter of pupils for measuring diameter of pupils
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/14—Arrangements specially adapted for eye photography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6802—Sensor mounted on worn items
    • A61B5/6803—Head-worn items, e.g. helmets, masks, headphones or goggles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813—Specially adapted to be attached to a specific body part
    • A61B5/6814—Head
    • A61B5/6821—Eye
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/74—Details of notification to user or communication with user or patient ; user input means
    • A61B5/746—Alarms related to a physiological condition, e.g. details of setting alarm thresholds or avoiding false alarms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/10—Eye inspection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/42—Details of probe positioning or probe attachment to the patient
    • A61B8/4209—Details of probe positioning or probe attachment to the patient by using holders, e.g. positioning frames
    • A61B8/4227—Details of probe positioning or probe attachment to the patient by using holders, e.g. positioning frames characterised by straps, belts, cuffs or braces
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/52—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/5215—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data
    • A61B8/5223—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data for extracting a diagnostic or physiological parameter from medical diagnostic data
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0204—Acoustic sensors

Definitions

  • the invention belongs to the technical field of anesthesia depth monitoring, in particular to an anesthesia depth monitoring system and detection method based on pupil changes under ultrasound.
  • Anesthesia can be described as a state of analgesia, unconsciousness, and muscle paralysis induced by specific drugs. Any overdose or underdose during anesthesia poses additional risks.
  • anesthesiologists judged the depth of analgesia based on experience and used physiological responses to assess inhibition of nociceptive pathways, such as movement, tachycardia, lacrimation, or sweating, which occurred relatively late, were insensitive, and were imprecise.
  • Processed electroencephalography EEG is widely used to monitor drug-induced hypnotic states, however, current monitoring methods do not fully meet clinical needs in terms of both analgesia and unconsciousness.
  • Pupil monitoring is an important index in the traditional anesthesia observation process. Regular and quantitative monitoring of pupils can reflect physiological arousal, reflect and evaluate autonomic nervous activity, reflect heart rate changes and realize non-contact and non-injury measurement of heart rate variability; helpful for coma , convulsions, shock, poisoning, respiratory failure and circulatory failure, especially for patients with craniocerebral injury, it can determine the location of intracranial injury.
  • Pupil changes can reflect the depth of anesthesia, but the existing pupil diameter measurement methods include manual measurement by doctors, infrared pupillometers or handheld ultrasonic pupillometers, which require the patient to cooperate with the doctor to make a certain posture, and the measurement requirements are high, resulting in the inability to accurately measure the pupillary diameter. Responses are measured quantitatively and the accuracy of pupillary observations cannot be guaranteed.
  • the purpose of the present invention is to provide an anesthesia depth monitoring system and detection method based on pupil changes under ultrasound.
  • the micro-ultrasonic probe of the ultrasonic monitoring device can obtain the patient's eye. Pupil ultrasound images, and display pupil changes through the monitor of the ultrasound host to monitor the depth of anesthesia.
  • the present invention adopts a kind of anesthesia depth monitoring system based on pupil changes under ultrasound, comprising:
  • Ultrasonic monitoring device which includes a head-mounted mounting part and two miniature ultrasonic probes, the two miniature ultrasonic probes are symmetrically arranged on both sides of the head-mounted mounting part, the position of one miniature ultrasonic probe corresponds to one eye, and the miniature ultrasonic probe fits Facial and pupillary ultrasound images obtained by ultrasound;
  • Ultrasound host which includes a monitor, and transmits the pupil ultrasound image acquired by the miniature ultrasound probe to the ultrasound host.
  • the ultrasound host processes the pupil ultrasound image, and displays the pupil image, the real-time value of pupil diameter, the average pupil diameter of both eyes, and the change of pupil diameter through the monitor.
  • Data information such as trend graphs;
  • the shading patch which is applied on the eyelids, eliminates the influence of indoor light on the pupil's light reflection and positions the ultrasonic monitoring device.
  • Two tiny ultrasound probes are placed on the outside of the eyes or the lower eyelids of the eyes respectively.
  • the head-mounted mounts include a first head-mounted mount, a second head-mounted mount, and a mask mount.
  • the first head-mounted mounting part includes an arc-shaped first elastic headband, two micro-ultrasound probes are symmetrically arranged at both ends of the first elastic headband, and the two micro-ultrasound probes are respectively arranged outside the eyes.
  • the second head-mounted mounting part includes a second elastic headband and a nose frame.
  • the nose frame is stuck on the bridge of the nose of the person's face.
  • Two micro-ultrasound probes are arranged symmetrically on both sides of the nose frame. The micro-ultrasound probes fit the lower eyelids of the eyes.
  • the mask-type installation includes a mask and straps.
  • the mask includes a first mask body and a second mask body.
  • the first mask body is connected to the ventilation pipeline, and the second mask body fits the facial contour around the eyes.
  • Two miniature ultrasonic probes are set on the In the installation groove of the second mask body, the miniature ultrasonic probe fits the lower eyelid of the eye, and the strap is fixedly installed on the mask.
  • the shading patch is a medical cold compress eye patch.
  • the ultrasonic host also includes a sound alarm module or a light alarm module.
  • the present invention adopts a detection method of an anesthesia depth monitoring system based on pupil changes under ultrasound, comprising the following steps:
  • the positions of the two micro-ultrasound probes correspond to the left and right eyes respectively, and adjust the micro-ultrasound probes to fit the face;
  • the micro-ultrasound probe emits and receives ultrasonic waves, monitors the left and right eyes, and obtains pupil ultrasonic images;
  • the pupil ultrasound image acquired by the micro-ultrasound probe is transmitted to the ultrasound host.
  • the ultrasound host processes the pupil ultrasound image and displays data information such as the pupil image, the real-time value of pupil diameter, the average pupil diameter of both eyes, and the trend chart through the monitor.
  • the transmission methods of the pupillary ultrasound image include bluetooth, wireless, and wired.
  • the patient wears a head-mounted ultrasonic monitoring device before anesthesia.
  • the miniature ultrasonic probe of the ultrasonic monitoring device fits the face, but does not cause pressure on the eyes.
  • the two micro-ultrasound probes of the ultrasonic monitoring device acquire the pupil ultrasound images of the patient's two eyes, and the ultrasound host processes the pupil ultrasound images, and displays the pupil images, real-time pupil diameter values, and the average pupil diameter of both eyes on the monitor.
  • the anesthesia depth can be judged through the pupil change to realize the monitoring of the anesthesia depth.
  • the pupil image can switch to observe a certain eye or observe the left and right eyes at the same time, and mark the pupil distance.
  • two micro-ultrasound probes can be placed on the outside of the eyes or on the lower eyelids of both eyes.
  • the position of the micro-ultrasound probes can be set flexibly, which reduces the use restrictions.
  • the position of the probes can be flexibly set according to the needs, ensuring the effect of anesthesia depth monitoring .
  • different head-mounted mounting parts can be used to install the miniature ultrasonic probe.
  • Fig. 1 is a flowchart of a detection method of an anesthesia depth monitoring system based on pupil changes under ultrasound.
  • FIG. 2 is a first structural schematic diagram of the first head-mounted mounting part in an anesthesia depth monitoring system based on pupil changes under ultrasound.
  • Fig. 3 is a second structural schematic diagram of the first head-mounted mounting part in an anesthesia depth monitoring system based on pupil changes under ultrasound.
  • Fig. 4 is a schematic structural diagram of the first elastic headband in an anesthesia depth monitoring system based on pupil changes under ultrasound.
  • Fig. 5 is a first structural schematic diagram of a second head-mounted mounting part in an anesthesia depth monitoring system based on pupil changes under ultrasound.
  • FIG. 6 is a second structural schematic diagram of a second head-mounted mounting part in an anesthesia depth monitoring system based on pupil changes under ultrasound.
  • Fig. 7 is a schematic structural diagram of a mask-type mounting part in an anesthesia depth monitoring system based on pupil changes under ultrasound.
  • the present invention provides a technical solution:
  • the present invention adopts an anesthesia depth monitoring system based on pupil changes under ultrasound, including:
  • Ultrasonic monitoring device which includes a head-mounted mount and two miniature ultrasonic probes 1, the two miniature ultrasonic probes 1 are symmetrically arranged on both sides of the head-mounted mount, one micro-ultrasonic probe 1 corresponds to one eye, and the miniature ultrasonic Probe 1 fits the face and obtains pupillary ultrasound images through ultrasound;
  • Ultrasound host which includes a display, transmits the pupil ultrasound image acquired by the micro-ultrasound probe 1 to the ultrasound host, and the ultrasound host processes the pupil ultrasound image, and displays the pupil image, the real-time value of the pupil diameter, the average value of the pupil diameter of both eyes, and the pupil diameter through the monitor.
  • Data information such as trend charts;
  • the shading patch which is applied on the eyelids, eliminates the influence of indoor light on the pupil's light reflection and positions the ultrasonic monitoring device.
  • the two micro-ultrasound probes 1 are respectively set on the outside of the eyes or the lower eyelids of both eyes, and the position of the micro-ultrasound probes 1 can be flexibly set according to the needs to better monitor the changes of the pupils, thereby realizing the monitoring of the depth of anesthesia.
  • the head-mounted mounts include a first head-mounted mount, a second head-mounted mount, and a mask mount.
  • the first head-mounted mounting part includes an arc-shaped first elastic headband 2, and two miniature ultrasonic probes 1 are symmetrically arranged at both ends of the first elastic headband 2, and the two miniature ultrasonic probes 1 are respectively arranged outside the eyes for ultrasonic monitoring.
  • the device is easy to wear.
  • the second head-mounted mounting part includes a second elastic headband 3 and a nose frame 4.
  • the nose frame 4 is stuck on the bridge of the nose of the personnel face.
  • Two miniature ultrasonic probes 1 are symmetrically arranged on both sides of the nose frame 4. Close the lower eyelid of the eye.
  • a couplant is placed between the micro-ultrasound probe 1 and the skin.
  • the micro-ultrasound probe 1 fits the face.
  • the thickness of the couplant can be adjusted to help adjust the angle of the ultrasonic probe.
  • the mask-type mounting part includes a mask 5 and a strap 6.
  • the mask 5 includes a first cover body 51 and a second cover body 52.
  • the first cover body 51 is connected to the ventilation pipeline, and the second cover body 52 fits the facial contour around the eyes.
  • two micro-ultrasound probes 1 are arranged in the installation groove of the second cover body 52, the micro-ultrasound probe 1 fits the lower eyelid of the eye, the strap 6 is fixedly installed on the mask 5, the mask 5 is fixed by the strap 6, the first Both the cover body 51 and the second cover body 52 are provided with straps to ensure the fixing effect.
  • the face mask has been improved in shape, and there are more second mask bodies 5 that fit the contours of the face.
  • the setting of the second mask body 5 makes the mask body relatively Compared with the traditional breathing mask, it does not compress the eyes and the probe when it is fixed, and does not leak air, ensuring the monitoring effect of pupil changes.
  • the shading patch is a medical cold compress eye patch, which can prevent the eyes from being dry for a long time under anesthesia, and can also prevent the indoor light from affecting the pupil's light reflex.
  • the ultrasound host also includes a sound alarm module or a light alarm module.
  • the ultrasound host sets a baseline value and an alarm value for pupil changes, and gives a sound or light alarm when the pupil changes exceed the alarm value.
  • the present invention adopts a detection method of an anesthesia depth monitoring system based on pupil changes under ultrasound, comprising the following steps:
  • the positions of the two micro-ultrasound probes 1 correspond to the left and right eyes respectively, and adjust the micro-ultrasound probe 1 to fit the face;
  • the micro-ultrasound probe 1 emits and receives ultrasonic waves, monitors the left and right eyes, and obtains pupil ultrasonic images;
  • the pupil ultrasonic image acquired by the miniature ultrasonic probe 1 is transmitted to the ultrasonic host, and the ultrasonic host processes the pupil ultrasonic image, and displays data information such as the pupil image, the real-time value of the pupil diameter, the average pupil diameter of both eyes, and the trend chart through the monitor.
  • the transmission methods of the pupillary ultrasound images include bluetooth, wireless, and wired, and data transmission can be performed in various ways.
  • the patient wears a head-mounted ultrasonic monitoring device.
  • the miniature ultrasonic probe of the ultrasonic monitoring device fits the face, but does not cause pressure on the eyes.
  • the two micro-ultrasound probes of the ultrasonic monitoring device acquire the pupil ultrasound images of the patient's two eyes, and the ultrasound host processes the pupil ultrasound images, and displays the pupil images, real-time pupil diameter values, and the average pupil diameter of both eyes on the monitor.
  • the anesthesia depth can be judged through the pupil change to realize the monitoring of the anesthesia depth.
  • the pupil image can switch to observe a certain eye or observe the left and right eyes at the same time, and mark the pupil distance.
  • the two micro-ultrasound probes can be set on the outside of the eyes or on the lower eyelids of the eyes.
  • the position of the micro-ultrasound probes can be set flexibly, which reduces the use restrictions.
  • the position of the probes can be flexibly set according to the needs to ensure the effect of anesthesia depth monitoring.
  • different head-mounted mounting parts can be used to install the miniature ultrasonic probe.

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Abstract

一种基于超声下瞳孔变化的麻醉深度监测系统和检测方法，基于超声下瞳孔变化的麻醉深度监测系统包括：超声监测装置，其包括头戴式安装件和两个微型超声探头（1），两个微型超声探头（1）对称布置在头戴式安装件两侧，微型超声探头（1）贴合面部并通过超声波获取瞳孔超声图像；超声主机，其包括显示器，微型超声探头（1）获取的瞳孔超声图像传输给超声主机，超声主机对瞳孔超声图像进行处理，并通过显示器显示瞳孔图像、瞳孔直径实时变化数值等；遮光贴，其敷贴在眼皮上。通过让患者佩戴头戴式的超声监测装置，在患者处于麻醉/镇静状态时，超声监测装置的微型探头监测瞳孔变化，实现麻醉深度的实时动态监测。

Description

一种基于超声下瞳孔变化的麻醉深度监测系统及检测方法 技术领域
本发明属于麻醉深度监测技术领域，尤其涉及一种基于超声下瞳孔变化的麻醉深度监测系统及检测方法。
背景技术
麻醉可以被描述为由特定药物诱导的镇痛、无意识和肌肉麻痹的状态。麻醉期间任何用药过量或不足的情况都会带来额外的风险。以前麻醉医生根据经验判断镇痛深度，使用生理反应来评估伤害感受通路的抑制，如运动、心动过速、流泪或出汗，这些症状发生的相对较晚，不敏感且不精确。处理后的脑电图(EEG)被广泛用于监测药物诱导的催眠状态，然而，就镇痛和无意识两方面而言，目前的监测方法还不能完全满足临床需要。
在传统麻醉观察过程中瞳孔监测是一个重要的指标，对瞳孔的定时定量监控可以反映生理觉醒，反映和评价自主神经活动，反映心率变化并实现无接触无损伤测量心率变异性；有助于昏迷、惊厥、休克、中毒、呼吸衰竭及循环衰竭患者的病情判断，尤其对颅脑损伤病人，可以判定颅内损伤部位。
瞳孔变化能够反映麻醉深度，但是现有的瞳孔直径测量方式包括医生的人工测量、红外瞳孔测量仪或手持超声瞳孔测量仪，需要患者配合医生做一定的姿势，测量的要求高，导致不能对瞳孔反应进行定量测量，且无法保证观测瞳孔的准确性。
发明内容
本发明的目的在于：提供一种基于超声下瞳孔变化的麻醉深度监测系统及检测方法，患者通过头戴式的超声监测装置，当处于麻醉状态时，超声监测装置的微型超声探头获取患者眼睛的瞳孔超声图像，并通过超声主机的显示器显示瞳孔变化情况，实现麻醉深度的监测。
为了实现上述目的，一方面，本发明采用了一种基于超声下瞳孔变化的麻醉 深度监测系统，包括：
超声监测装置，其包括头戴式安装件和两个微型超声探头，两个微型超声探头对称布置在头戴式安装件两侧，一个微型超声探头的位置对应一只眼睛，微型超声探头贴合面部并通过超声波获取瞳孔超声图像；
超声主机，其包括显示器，微型超声探头获取的瞳孔超声图像传输给超声主机，超声主机对瞳孔超声图像进行处理，并通过显示器显示瞳孔图像、瞳孔直径实时数值、双眼瞳孔直径平均值、瞳孔直径变化趋势图等数据信息；
遮光贴，其敷贴在眼皮上，遮光贴消除室内光线对瞳孔对光反射的影响，并定位超声监测装置。
作为上述技术方案的进一步描述：
两个微型超声探头分别设置在双眼外侧或双眼的下眼睑处。
作为上述技术方案的进一步描述：
头戴式安装件包括第一头戴式安装件、第二头戴式安装件和面罩式安装件。
作为上述技术方案的进一步描述：
第一头戴式安装件包括弧形的第一弹力头带，两个微型超声探头对称布置在第一弹力头带两端，两个微型超声探头分别设置在双眼外侧。
作为上述技术方案的进一步描述：
第二头戴式安装件包括第二弹力头带和鼻架，鼻架卡在人员面部的鼻梁上，两个微型超声探头对称布置在鼻架两侧，微型超声探头贴合眼睛的下眼睑。
作为上述技术方案的进一步描述：
面罩式安装件包括面罩和绑带，面罩包括第一罩体和第二罩体，第一罩体连接通气管路，第二罩体贴合眼部周围的面部轮廓，两个微型超声探头设置在第二罩体的安装槽内，微型超声探头贴合眼睛的下眼睑，绑带固定安装在面罩上。
作为上述技术方案的进一步描述：
遮光贴为医用冷敷眼贴。
作为上述技术方案的进一步描述：
超声主机还包括声音报警模块或灯光报警模块。
另一方面，本发明采用了一种基于超声下瞳孔变化的麻醉深度监测系统的检测方法，包括以下步骤：
1)为患者戴上超声监测装置，两个微型超声探头位置分别对应左、右眼，调整微型超声探头贴合面部；
2)在患者的眼皮上敷贴遮光贴，遮光贴定位超声监测装置；
3)微型超声探头发射接收超声波，对左、右眼进行监测，获取瞳孔超声图像；
4)微型超声探头获取的瞳孔超声图像传输给超声主机，超声主机对瞳孔超声图像进行处理，并通过显示器显示瞳孔图像、瞳孔直径实时数值、双眼瞳孔直径平均值、变化趋势图等数据信息。
作为上述技术方案的进一步描述：
在步骤4)中，瞳孔超声图像的传输方式包括蓝牙、无线、有线。
综上所述，由于采用了上述技术方案，本发明的有益效果是：
1、本发明中，患者麻醉之前先佩戴头戴式的超声监测装置，超声监测装置的微型超声探头贴合面部，但不会对眼部造成压迫。当处于麻醉状态时，超声监测装置的两个微型超声探头获取患者两只眼睛的瞳孔超声图像，超声主机对瞳孔超声图像进行处理，并通过显示器显示瞳孔图像、瞳孔直径实时数值、双眼瞳孔直径平均值、瞳孔直径变化趋势图等数据信息，通过瞳孔变化判断麻醉深度，实现麻醉深度监测。瞳孔图像可切换观测某一只眼或同时观测左右眼，标注瞳孔距离。
2、本发明中，两个微型超声探头可以设置双眼外侧或双眼的下眼睑处，微型超声探头的位置设置灵活，减少了使用限制，可根据需求灵活设置探头的位置，保证麻醉深度监测的效果。相应的，可以采用不同的头戴式安装件来安装微型超 声探头。
附图说明
为了更清楚地说明本发明实施例的技术方案，下面将对实施例中所需要使用的附图作简单地介绍，应当理解，以下附图仅示出了本发明的某些实施例，因此不应被看作是对范围的限定，对于本领域普通技术人员来讲，在不付出创造性劳动的前提下，还可以根据这些附图获得其他相关的附图。
图1为一种基于超声下瞳孔变化的麻醉深度监测系统的检测方法的流程图。
图2为一种基于超声下瞳孔变化的麻醉深度监测系统中第一头戴式安装件的结构示意图一。
图3为一种基于超声下瞳孔变化的麻醉深度监测系统中第一头戴式安装件的结构示意图二。
图4为一种基于超声下瞳孔变化的麻醉深度监测系统中第一弹力头带的结构示意图。
图5为一种基于超声下瞳孔变化的麻醉深度监测系统中第二头戴式安装件的结构示意图一。
图6为一种基于超声下瞳孔变化的麻醉深度监测系统中第二头戴式安装件的结构示意图二。
图7为一种基于超声下瞳孔变化的麻醉深度监测系统中面罩式安装件的结构示意图。
图例说明：
1、微型超声探头；2、第一弹力头带；3、第二弹力头带；4、鼻架；5、面罩；51、第一罩体；52、第二罩体；6、绑带。
具体实施方式
下面将结合本发明实施例中的附图，对本发明实施例中的技术方案进行清 楚、完整地描述，显然，所描述的实施例仅仅是本发明一部分实施例，而不是全部的实施例。基于本发明中的实施例，本领域普通技术人员在没有作出创造性劳动前提下所获得的所有其它实施例，都属于本发明保护的范围。
请参阅图1-7，本发明提供一种技术方案：一方面，本发明采用了一种基于超声下瞳孔变化的麻醉深度监测系统，包括：
超声监测装置，其包括头戴式安装件和两个微型超声探头1，两个微型超声探头1对称布置在头戴式安装件两侧，一个微型超声探头1的位置对应一只眼睛，微型超声探头1贴合面部并通过超声波获取瞳孔超声图像；
超声主机，其包括显示器，微型超声探头1获取的瞳孔超声图像传输给超声主机，超声主机对瞳孔超声图像进行处理，并通过显示器显示瞳孔图像、瞳孔直径实时数值、双眼瞳孔直径平均值、瞳孔直径变化趋势图等数据信息；
遮光贴，其敷贴在眼皮上，遮光贴消除室内光线对瞳孔对光反射的影响，并定位超声监测装置。
两个微型超声探头1分别设置在双眼外侧或双眼的下眼睑处，根据需求灵活的设置微型超声探头1的位置，以更好的监测瞳孔变化，从而实现麻醉深度的监测。
头戴式安装件包括第一头戴式安装件、第二头戴式安装件和面罩式安装件。
第一头戴式安装件包括弧形的第一弹力头带2，两个微型超声探头1对称布置在第一弹力头带2两端，两个微型超声探头1分别设置在双眼外侧，超声监测装置佩戴方便。
第二头戴式安装件包括第二弹力头带3和鼻架4，鼻架4卡在人员面部的鼻梁上，两个微型超声探头1对称布置在鼻架4两侧，微型超声探头1贴合眼睛的下眼睑。微型超声探头1设置在下眼睑处时，微型超声探头1与皮肤之间设置耦合剂，一方面使得微型超声探头1契合面部，另一方面可通过调整耦合剂厚薄，协助调节超声探头的角度。
面罩式安装件包括面罩5和绑带6，面罩5包括第一罩体51和第二罩体52，第一罩体51连接通气管路，第二罩体52贴合眼部周围的面部轮廓，两个微型超声探头1设置在第二罩体52的安装槽内，微型超声探头1贴合眼睛的下眼睑，绑带6固定安装在面罩5上，面罩5通过绑带6固定，第一罩体51和第二罩体52上都设置有绑带，保证固定效果。面罩相对于传统的呼吸面罩进行了外形改良，多了与面部轮廓契合的第二罩体5，第二罩体5内留有放置微型超声探头的空间，第二罩体5的设置使得面罩相较于传统的呼吸面罩，在固定时不压迫眼睛以及探头，不漏气，保证瞳孔变化监测效果。
遮光贴为医用冷敷眼贴，防止长时间处于麻醉状态，眼睛干涩，也可防止室内光线对瞳孔对光反射的影响。
超声主机还包括声音报警模块或灯光报警模块，超声主机为瞳孔变化设定基线值和报警值，瞳孔变化超出报警值时进行声音或灯光报警。
另一方面，本发明采用了一种基于超声下瞳孔变化的麻醉深度监测系统的检测方法，包括以下步骤：
1)为患者戴上超声监测装置，两个微型超声探头1位置分别对应左、右眼，调整微型超声探头1贴合面部；
2)在患者的眼皮上敷贴遮光贴，遮光贴定位超声监测装置；
3)微型超声探头1发射接收超声波，对左、右眼进行监测，获取瞳孔超声图像；
4)微型超声探头1获取的瞳孔超声图像传输给超声主机，超声主机对瞳孔超声图像进行处理，并通过显示器显示瞳孔图像、瞳孔直径实时数值、双眼瞳孔直径平均值、变化趋势图等数据信息。
在步骤4)中，瞳孔超声图像的传输方式包括蓝牙、无线、有线，可通过多种方式进行数据传输。
工作原理：患者麻醉之前先佩戴头戴式的超声监测装置，超声监测装置的微 型超声探头贴合面部，但不会对眼部造成压迫。当处于麻醉状态时，超声监测装置的两个微型超声探头获取患者两只眼睛的瞳孔超声图像，超声主机对瞳孔超声图像进行处理，并通过显示器显示瞳孔图像、瞳孔直径实时数值、双眼瞳孔直径平均值、瞳孔直径变化趋势图等数据信息，通过瞳孔变化判断麻醉深度，实现麻醉深度监测。瞳孔图像可切换观测某一只眼或同时观测左右眼，标注瞳孔距离。两个微型超声探头可以设置双眼外侧或双眼的下眼睑处，微型超声探头的位置设置灵活，减少了使用限制，可根据需求灵活设置探头的位置，保证麻醉深度监测的效果。相应的，可以采用不同的头戴式安装件来安装微型超声探头。
以上所述，仅为本发明较佳的具体实施方式，但本发明的保护范围并不局限于此，任何熟悉本技术领域的技术人员在本发明揭露的技术范围内，根据本发明的技术方案及其发明构思加以等同替换或改变，都应涵盖在本发明的保护范围之内。

Claims (10)

  1. 一种基于超声下瞳孔变化的麻醉深度监测系统，其特征在于，包括：
    超声监测装置，其包括头戴式安装件和两个微型超声探头(1)，两个所述微型超声探头(1)对称布置在所述头戴式安装件两侧，一个所述微型超声探头(1)的位置对应一只眼睛，所述微型超声探头(1)贴合面部并通过超声波获取瞳孔超声图像；
    超声主机，其包括显示器，所述微型超声探头(1)获取的瞳孔超声图像传输给所述超声主机，所述超声主机对瞳孔超声图像进行处理，并通过所述显示器显示瞳孔图像、瞳孔直径实时数值、双眼瞳孔直径平均值、瞳孔直径变化趋势图等数据信息；
    遮光贴，其敷贴在眼皮上，所述遮光贴消除室内光线对瞳孔对光反射的影响，并定位所述超声监测装置。
  2. 根据权利要求1所述的一种基于超声下瞳孔变化的麻醉深度监测系统，其特征在于，两个所述微型超声探头(1)分别设置在双眼外侧或双眼的下眼睑处。
  3. 根据权利要求2所述的一种基于超声下瞳孔变化的麻醉深度监测系统，其特征在于，所述头戴式安装件包括第一头戴式安装件、第二头戴式安装件和面罩式安装件。
  4. 根据权利要求3所述的一种基于超声下瞳孔变化的麻醉深度监测系统，其特征在于，所述第一头戴式安装件包括弧形的第一弹力头带(2)，两个所述微型超声探头(1)对称布置在所述第一弹力头带(2)两端，两个所述微型超声探头(1)分别设置在双眼外侧。
  5. 根据权利要求3所述的一种基于超声下瞳孔变化的麻醉深度监测系统，其特征在于，所述第二头戴式安装件包括第二弹力头带(3)和鼻架(4)，所述鼻架(4)卡在人员面部的鼻梁上，两个所述微型超声探头(1)对称布置在所述鼻架(4)两侧，所述微型超声探头(1)贴合眼睛的下眼睑。
  6. 根据权利要求3所述的一种基于超声下瞳孔变化的麻醉深度监测系统，其特征在于，所述面罩式安装件包括面罩(5)和绑带(6)，所述面罩(5)包括第一罩体(51)和第二罩体(52)，所述第一罩体(51)连接通气管路，所述第二罩体(52)贴合眼部周围的面部轮廓，两个所述微型超声探头(1)设置在所述第二罩体(52)的安装槽内，所述微型超声探头(1)贴合眼睛的下眼睑，所述绑带(6)固定安装在所述面罩(5)上。
  7. 根据权利要求1所述的一种基于超声下瞳孔变化的麻醉深度监测系统，其特征在于，所述遮光贴为医用冷敷眼贴。
  8. 根据权利要求1所述的一种基于超声下瞳孔变化的麻醉深度监测系统，其特征在于，所述超声主机还包括声音报警模块或灯光报警模块。
  9. 一种基于超声下瞳孔变化的麻醉深度监测系统的检测方法，其特征在于，包括以下步骤：
    1)为患者戴上超声监测装置，两个微型超声探头(1)位置分别对应左、右眼，调整所述微型超声探头(1)贴合面部；
    2)在患者的眼皮上敷贴遮光贴，遮光贴定位超声监测装置；
    3)所述微型超声探头(1)发射接收超声波，对左、右眼进行监测，获取瞳孔超声图像；
    4)所述微型超声探头(1)获取的瞳孔超声图像传输给超声主机，超声主机对瞳孔超声图像进行处理，并通过显示器显示瞳孔图像、瞳孔直径实时数值、双眼瞳孔直径平均值、变化趋势图等数据信息。
  10. 根据权利要求9所述的一种基于超声下瞳孔变化的麻醉深度监测系统的检测方法，其特征在于，在所述步骤4)中，瞳孔超声图像的传输方式包括蓝牙、无线、有线。
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CN113558575A (zh) * 2021-07-20 2021-10-29 苏州科技城医院 一种基于超声下瞳孔变化的麻醉深度监测系统及检测方法
CN216021126U (zh) * 2021-07-20 2022-03-15 苏州科技城医院 一种头戴式瞳孔变化监测用超声装置

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