WO2022235066A1 - Structure mobile pour diagnostic - Google Patents

Structure mobile pour diagnostic Download PDF

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Publication number
WO2022235066A1
WO2022235066A1 PCT/KR2022/006363 KR2022006363W WO2022235066A1 WO 2022235066 A1 WO2022235066 A1 WO 2022235066A1 KR 2022006363 W KR2022006363 W KR 2022006363W WO 2022235066 A1 WO2022235066 A1 WO 2022235066A1
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WO
WIPO (PCT)
Prior art keywords
space
front room
open area
mobile structure
opening
Prior art date
Application number
PCT/KR2022/006363
Other languages
English (en)
Inventor
Seong Youl Kim
Hae Hui PARK
Sung Eun Kim
Original Assignee
Seegene, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seegene, Inc. filed Critical Seegene, Inc.
Priority to KR1020237040145A priority Critical patent/KR20230173183A/ko
Publication of WO2022235066A1 publication Critical patent/WO2022235066A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61G—TRANSPORT, PERSONAL CONVEYANCES, OR ACCOMMODATION SPECIALLY ADAPTED FOR PATIENTS OR DISABLED PERSONS; OPERATING TABLES OR CHAIRS; CHAIRS FOR DENTISTRY; FUNERAL DEVICES
    • A61G3/00—Ambulance aspects of vehicles; Vehicles with special provisions for transporting patients or disabled persons, or their personal conveyances, e.g. for facilitating access of, or for loading, wheelchairs
    • A61G3/001—Vehicles provided with medical equipment to perform operations or examinations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61G—TRANSPORT, PERSONAL CONVEYANCES, OR ACCOMMODATION SPECIALLY ADAPTED FOR PATIENTS OR DISABLED PERSONS; OPERATING TABLES OR CHAIRS; CHAIRS FOR DENTISTRY; FUNERAL DEVICES
    • A61G10/00—Treatment rooms or enclosures for medical purposes
    • A61G10/02—Treatment rooms or enclosures for medical purposes with artificial climate; with means to maintain a desired pressure, e.g. for germ-free rooms
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B60—VEHICLES IN GENERAL
    • B60P—VEHICLES ADAPTED FOR LOAD TRANSPORTATION OR TO TRANSPORT, TO CARRY, OR TO COMPRISE SPECIAL LOADS OR OBJECTS
    • B60P3/00—Vehicles adapted to transport, to carry or to comprise special loads or objects
    • B60P3/14—Vehicles adapted to transport, to carry or to comprise special loads or objects the object being a workshop for servicing, for maintenance, or for carrying workmen during work
    • E—FIXED CONSTRUCTIONS
    • E04—BUILDING
    • E04H—BUILDINGS OR LIKE STRUCTURES FOR PARTICULAR PURPOSES; SWIMMING OR SPLASH BATHS OR POOLS; MASTS; FENCING; TENTS OR CANOPIES, IN GENERAL
    • E04H3/00—Buildings or groups of buildings for public or similar purposes; Institutions, e.g. infirmaries or prisons
    • E04H3/08—Hospitals, infirmaries, or the like; Schools; Prisons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2209/00—Aspects relating to disinfection, sterilisation or deodorisation of air
    • A61L2209/10—Apparatus features
    • A61L2209/14—Filtering means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2209/00—Aspects relating to disinfection, sterilisation or deodorisation of air
    • A61L2209/10—Apparatus features
    • A61L2209/16—Connections to a HVAC unit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L9/00—Disinfection, sterilisation or deodorisation of air
    • A61L9/16—Disinfection, sterilisation or deodorisation of air using physical phenomena
    • A61L9/18—Radiation
    • A61L9/20—Ultraviolet radiation
    • E—FIXED CONSTRUCTIONS
    • E04—BUILDING
    • E04H—BUILDINGS OR LIKE STRUCTURES FOR PARTICULAR PURPOSES; SWIMMING OR SPLASH BATHS OR POOLS; MASTS; FENCING; TENTS OR CANOPIES, IN GENERAL
    • E04H1/00—Buildings or groups of buildings for dwelling or office purposes; General layout, e.g. modular co-ordination or staggered storeys
    • E04H1/12—Small buildings or other erections for limited occupation, erected in the open air or arranged in buildings, e.g. kiosks, waiting shelters for bus stops or for filling stations, roofs for railway platforms, watchmen's huts or dressing cubicles
    • E04H2001/1283—Small buildings of the ISO containers type
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F24—HEATING; RANGES; VENTILATING
    • F24F—AIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
    • F24F11/00—Control or safety arrangements
    • F24F11/0001—Control or safety arrangements for ventilation
    • F24F2011/0002—Control or safety arrangements for ventilation for admittance of outside air
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F24—HEATING; RANGES; VENTILATING
    • F24F—AIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
    • F24F8/00—Treatment, e.g. purification, of air supplied to human living or working spaces otherwise than by heating, cooling, humidifying or drying
    • F24F8/10—Treatment, e.g. purification, of air supplied to human living or working spaces otherwise than by heating, cooling, humidifying or drying by separation, e.g. by filtering
    • F24F8/108—Treatment, e.g. purification, of air supplied to human living or working spaces otherwise than by heating, cooling, humidifying or drying by separation, e.g. by filtering using dry filter elements

Definitions

  • the present disclosure relates to a mobile structure for diagnosis.
  • the 21st century healthcare paradigm is changing from the era of disease treatment through the era of public health to the era of health and life extension by means of the prevention and management of diseases.
  • IVD in vitro diagnostics
  • IVD in vitro diagnostics
  • the aging of the global population and the emergence of new viruses are additional factors in the growth of the in vitro diagnostic market.
  • treatment is also shifting to personalized treatment, and the scope of in vitro diagnostics on a patient undertaken before deciding on a treatment or prescription for the patient is also expanding.
  • Such in vitro diagnostics include various types of diagnostics.
  • immune-based diagnostics based on proteins, such as antigens and antibodies
  • nucleic acid-based diagnostics based on nucleic acids, such as deoxyribonucleic acid (DNA) or ribonucleic acid (RNA).
  • DNA deoxyribonucleic acid
  • RNA ribonucleic acid
  • nucleic acid-based diagnostics is the fastest growing field among in vitro diagnostics and plays a key role in the continuity of patient management. Compared to other diagnostic platforms with overlapping disease portfolios, nucleic acid-based diagnostics is advantageous in terms of, for example, superior test precision, the possibility of equipment miniaturization, and fast processing times.
  • Such nucleic acid-based diagnosis is performed by the following steps: first, a nucleic acid is extracted from a sample. Afterwards, the extracted nucleic acid is mixed with a nucleic acid detection reaction solution. Subsequently, whether a target nucleic acid is present in the mixed result is determined or detected.
  • steps are performed using at least one device.
  • the steps may be performed using a dispenser also referred to as a liquid handling device, a nucleic acid extraction device, a setup device, a nucleic acid detection device, and the like.
  • the amount of a sample handled using each device and a reagent administered to the sample may be, for example, several to several hundred milliliters or, in some cases, several to several hundred microliters.
  • each device is designed to perform highly precise/precise movements.
  • a high level of professionalism is also required in the process of installing or operating each device.
  • facilities are required to prevent leakage of pathogens that may exist in a specific sample.
  • the environment in which these devices are provided must also meet strict predetermined requirements.
  • an objective of the present disclosure is to enable devices performing respective steps of nucleic acid-based diagnosis to be easily used and operated anywhere in the world.
  • a mobile structure for diagnosis including: a housing comprising a space therein to accommodate diagnostic equipment, with a housing open area being formed in the housing; and a front room part connected to peripheral portions of the housing open area to seal the housing open area and providing a size-variable front room to a portion of the space of the housing.
  • the front room part may include: a wall part defining an internal space of the front room; and a sealing-connecting part connecting one end of the wall part to the peripheral portions of the housing open area in a sealing manner.
  • the wall part may include a urethane material.
  • the wall part may have a foldable structure to minimize the size of the front room when folded and maximize the size of the front room when unfolded.
  • the front room part may further include a guide part extending in a direction from the housing open area to the space.
  • the size of the front room may vary as the other end of the wall part slides along the guide part.
  • the front room part may further include a front room opening/closing part to open and close a front room open area provided in the wall part.
  • the front room opening/closing part may include a zipper member or a magnet member to open and close the front room open area.
  • the mobile structure for diagnosis may further include: a housing open area opening/closing part to open and close the housing open area; and an atmospheric pressure adjustment part to adjust the atmospheric pressure of the space.
  • the atmospheric pressure of the space adjusted by the atmospheric pressure adjustment part may be maintained when the front room open area is closed by the front room opening/closing part even though the housing open area is opened by the housing open area opening/closing part.
  • the mobile structure may further include: a housing open area opening/closing part to open and close the housing open area; and an opening/closing adjustment part to control at least one of the housing open area opening/closing part and the front room opening/closing part so that, when one of the housing open area opening/closing part and the front room opening/closing part is opened, the other of the housing open area opening/closing part and the front room opening/closing part is not opened.
  • the mobile structure may further include: a housing open area opening/closing part to open and close the housing open area; and an alarm generator to generate a warning signal when both the housing open area opening/closing part and the front room opening/closing part are opened.
  • a diagnosis vehicle including: the above-described mobile structure for diagnosis; and a vehicle connected to the mobile structure for diagnosis.
  • the vehicle may be a vibration-free vehicle.
  • nucleic acid based diagnosis can be performed by the mobile diagnostic structure in the area where the facilities or environments for the nucleic acid based diagnosis are not provided.
  • specific illness or disease can be detected throughout the world or the country without missing regions. Thereby, overall monitoring for the specific illness or disease can be facilitated, as well as preventive measures against epidemics can be carefully established when the epidemics are generated.
  • an introduction path through which a raw sample collected from a sample provider is introduced into the mobile structure for diagnosis
  • a movement path through which an operator handling the introduced raw sample moves
  • the sample is delivered by the delivery part rather than by a person.
  • the delivery of air or pathogens between respective spaces can be minimized, thereby minimizing the risk of contamination or infection.
  • a calibration warning signal for the devices installed inside the mobile structure for diagnosis is generated.
  • the status of nucleic acid-based diagnosis devices designed to perform highly sophisticated/precise movements can be managed optimally, and thus an accurate nucleic acid-based diagnosis result can be derived.
  • the front room may be provided in the pretreatment space.
  • the level of atmospheric pressure, for example, negative pressure, provided to the pretreatment space may be maintained even in the case in which the entrance between the pretreatment space and the outside is opened.
  • the size of the front room in the pretreatment space may be changed or variable.
  • the front room may have a predetermined volume when an operator is required to move between the pretreatment space and the outside.
  • the front room may have a minimum volume. Accordingly, even in the case in which the mobile structure for diagnosis has a limited internal space, the front room for maintaining negative pressure may be provided regardless of the size of the internal space.
  • FIG. 1 schematically illustrates a situation in which regional hubs performing nucleic acid based diagnosis are disposed only in some regions among a plurality of regions, but not in the other regions, and a situation in which detection results detected from the regional hubs disposed in some regions are transmitted to a control center are conceptually illustrated.
  • FIG. 2 schematically illustrates a situation in which the mobile structure for diagnosis according to the first embodiment is disposed in the remaining regions and is conceptually illustrated;
  • FIG. 3 is a perspective diagram illustrating the appearance of the mobile structure for diagnosis according to the first embodiment
  • FIGS. 4 and 5 are left elevation diagrams illustrating the appearance of the mobile structure for diagnosis according to the first embodiment
  • FIGS. 6 and 7 are right elevation diagrams illustrating the appearance of the mobile structure for diagnosis according to the first embodiment
  • FIGS. 8 to 11 are schematic diagrams illustrating the internal structure of the mobile structure for diagnosis
  • FIG. 12 illustrates a negative pressure arrangement in the internal space of the mobile structure for diagnosis
  • FIG. 13 is a perspective diagram illustrating an inlet part open area formed in the housing and the inlet part disposed in the inlet part open area in the mobile structure for diagnosis according to the first embodiment
  • FIG. 14 is a perspective diagram illustrating another example of the inlet part disposed in the inlet part open area in the mobile structure for diagnosis according to the first embodiment
  • FIG. 15 is a schematic diagram illustrating a configuration of the door opening/closing adjustment part
  • FIG. 16 is a perspective diagram illustrating a delivery part open area provided in the wall part of the partitioning part and the delivery part disposed in the delivery part open area in the mobile structure for diagnosis according to the first embodiment;
  • FIG. 17 is a perspective diagram illustrating another example of the delivery part open area provided in the wall part of the partitioning part and the delivery part disposed in the delivery part open area in the mobile structure for diagnosis according to the first embodiment;
  • FIG. 18 is a table illustrating example internal atmospheric pressures of the intermediate chamber of the delivery part adjusted using the atmospheric pressure adjustment part
  • FIG. 19 is a schematic diagram illustrating a configuration of the door opening/closing adjustment part to adjusting the opening and closing of the door of the delivery part;
  • FIG. 20 is a schematic diagram illustrating additional components of the mobile structure for diagnosis according to the first embodiment
  • FIG. 21 is a schematic diagram illustrating a process flow on which a sample is processed in the mobile structure for diagnosis according to the first embodiment
  • FIGS. 22 to 26 are snapshot virtual images illustrating situations that may actually occur in the mobile structure for diagnosis
  • FIG. 28 is a flowchart illustrating the process flow illustrated in FIG. 21;
  • FIGS. 29 and 30 are perspective diagrams illustrating an internal structure of a mobile structure for diagnosis according to a second embodiment
  • FIG. 31 is a plan diagram illustrating the internal structure of the mobile structure for diagnosis according to the second embodiment.
  • FIGS. 32 to 35 illustrate portions of an internal structure of a mobile structure for diagnosis according to a third embodiment.
  • an analyte is an antigen, an antibody, an enzyme or a nucleic acid.
  • a sample refers to a material that contains or is estimated to contain the above-described analyte.
  • the object of analysis or detection is to determine whether an analyte is contained in the sample.
  • samples include biological samples and non-biological samples.
  • biological samples include at least one of viruses, bacteria, tissues, cells, blood (including whole blood, plasma, and serum), lymph, bone marrow fluid, sputum, swab, aspiration, bronchial lavage fluid, bronchoalveolar lavage fluid, nasal lavage fluid, milk, urine, excrement, ocular fluid, saliva, semen, brain extract, spinal fluid (SCF), joint fluid, appendix, spleen and tonsil tissue extract, amniotic fluid, and abnormal serous fluid, but are not limited thereto.
  • viruses include at least one of viruses, bacteria, tissues, cells, blood (including whole blood, plasma, and serum), lymph, bone marrow fluid, sputum, swab, aspiration, bronchial lavage fluid, bronchoalveolar lavage fluid, nasal lavage fluid, milk, urine, excrement, ocular fluid, saliva, semen, brain extract, spinal fluid (SCF), joint fluid, appendix, spleen and tonsil tissue extract, amn
  • non-biological samples may include, for example, at least one of food, water, and soil.
  • At least one of a pretreatment operation, a nucleic acid extraction operation, a setup operation, and an analysis operation may be sequentially performed on samples.
  • the pretreatment operation may include unpacking and deactivation.
  • the unpacking operation refers to an operation of unpacking a container when a sample is packed in the container.
  • the deactivation operation refers to an operation of reducing or removing the activity of an activated sample.
  • the nucleic acid extraction operation refers to an operation of extracting nucleic acids from a sample.
  • the nucleic acid extraction operation may be performed in a variety of methods.
  • the nucleic acid extraction operation may be performed by one of a method of using a cell lysis solution, a method of using heating instead of using a cell lysis solution, a method of using a separate enzyme (PKase), a method of using a separate chemical, and combinations of at least two thereof.
  • PKase separate enzyme
  • the setup operation refers to an operation of preparing a reagent or the like so that a nucleic acid can be detected.
  • the setup operation may include an operation of mixing a reagent necessary for detection of a nucleic acid with a sample or an operation for an IC or PC, but is not limited thereto.
  • the analysis operation includes an operation of detecting a signal generated depending on the amount of a nucleic acid, if any, present in the sample.
  • the analysis operation may include a genetic analysis process, such as polymerase chain reaction (PCR), real-time PCR, or microarray analysis.
  • the signal may include an optical signal.
  • various methods are known as a method for detecting an optical signal. Representative examples thereof include TaqMan TM probe method (United States Patent No. 5,210,015), a molecular beacon method (Tyagi et al., Nature Biotechnology v.14 MARCH 1996), a Scorpion method (Whitcombe et al., Nature Biotechnology 17:804-807(1999)), a Sunrise or Amplifluor method (Nazarenko et al., 2516-2521 Nucleic Acids Research, 25(12):2516-2521(1997), and United States Patent No. 6,117,635), an LUX method (United States Patent No.
  • PTOCE PTO cleavage and extension
  • PCE-SH PTO cleavage and extension-dependent signaling oligonucleotide hybridization
  • a nucleic acid amplification reaction may be performed by various methods according to embodiments.
  • amplification methods include: polymerase chain reaction (PCR), ligase chain reaction (LCR) (United States Patent Nos. 4,683,195 and 4,683,202; PCR Protocols: A Guide to Methods and Applications (Innis et al., eds, 1990)), strand displacement amplification (SDA) (Walker, et al. Nucleic Acids Res. 20(7):1691-6 (1992), Walker PCR Methods Appl. 3(1):1-6 (1993)), transcription-mediated amplification (Phyffer, et al., J. Clin. Microbiol.
  • a nucleic acid amplification reaction involving a temperature change may be performed.
  • a cycle comprised of a denaturing step, an annealing step, and an extension (or amplification) step may be repeatedly performed dozens of times.
  • a raw sample refers to a sample from after the sample is obtained from a sample provider to immediately before the above-described pretreatment operation is performed.
  • the raw sample may be packed in a container such as a tube.
  • the tube may contain a preservative for preserving the raw sample or a deactivating agent for deactivating the raw sample.
  • a pretreatment sample may refer to a sample from immediately after the above-described pretreatment operation is performed to immediately before the above-described setup operation is performed, i.e., a sample in the pretreatment operation and the nucleic acid extraction operation.
  • an analysis sample may refer to a sample from after the above-described setup operation is performed until the above-described analysis operation is completed, i.e., a sample in the setup operation and the analysis operation.
  • a space refers to a space in which various operations, such as a pretreatment operation, a nucleic acid extraction operation, a setup operation, and an analysis operation, are performed on a sample.
  • the space may include a pretreatment space, an analysis space, a first servant space, and a second servant space.
  • the pretreatment space the above-described pretreatment operation and the nucleic acid extraction operation are performed.
  • the setup operation and the analysis operation are performed.
  • the pretreatment space is sealed from the outside and other spaces.
  • the internal atmospheric pressure of the pretreatment space is adjustable, with respect to an external atmospheric pressure or an internal atmospheric pressure of the analysis space to be described later.
  • the internal atmospheric pressure of the pretreatment space may be a negative pressure compared to the external atmospheric pressure and the internal atmospheric pressure of the analysis space to be described later while the above-described pretreatment operation is performed, and may be the same as the outside atmospheric pressure at other times, but is not limited thereto.
  • the internal atmospheric pressure of the analysis space may be adjusted in comparison to the external atmospheric pressure or the internal atmospheric pressure of the pretreatment space.
  • the internal atmospheric pressure of the analysis space may be a positive pressure compared to the internal atmospheric pressure of the pretreatment space, but is not limited thereto.
  • first servant space and the second servant space refer to spaces other than the pretreatment space and the analysis space in the above-described spaces, respectively.
  • devices for providing a constant temperature and constant humidity function to the pretreatment space and the analysis space may be disposed or devices for providing power or a negative pressure to the devices disposed in the pretreatment space or the analysis space devices may be disposed.
  • Various devices or components not mentioned may be disposed in the first servant space and the second servant space.
  • the pretreatment sample may refer to a sample from after the above-described pretreatment operation is performed to immediately before the above-described analysis operation is performed, i.e., a sample in the pretreatment operation, the nucleic acid extraction operation, and the setup operation.
  • the analysis sample may refer to a sample from after the above-described analysis operation is performed until the analysis operation is completed.
  • the pretreatment operation, the nucleic acid extraction operation, and the setup operation described above are performed in the pretreatment space, and the analysis operation is performed in the analysis space.
  • the pretreatment sample may refer to a sample from after the above-described pre-treatment operation is performed until the above-described pre-treatment operation is completed, i.e., a sample in the pretreatment operation.
  • the analysis sample may refer to a sample from after the above-described nucleic acid extraction operation is performed until the setup operation and the analysis operation are completed.
  • the above-described pretreatment operation is performed in the pretreatment space, and the acid extraction operation, the setup operation, and the analysis operation are performed in the analysis space.
  • FIG. 1 a situation in which, only in some regions 1 to 5 among a plurality of regions 1 to 7, a regional hub institution (hereinafter, referred to as a regional hub) 60 carrying out nucleic acid based diagnosis is disposed, but not in the other regions 6 and 7, and a situation in which detection results that are detected from the regional hub 60 disposed in some regions 1 to 5 are transmitted to a control center (or central control institution) 40 are conceptually illustrated.
  • a regional hub institution hereinafter, referred to as a regional hub 60 carrying out nucleic acid based diagnosis
  • the regions 1 to 7 may be given districts (e.g., administrative districts) that belong to the same country or countries different from each other.
  • the regional hub 60 refers to clinics and hospitals where equipment and environments for the nucleic acid based diagnosis are provided.
  • the control center 40 refers to clinics and hospitals or national institutes where the detection results performed at each of the regional hubs 60 are collected and administered.
  • the aforementioned regional hub 60 is disposed only in some regions 1 to 5 among the regions 1 to 7 divided in the plural number.
  • humans or animals who live in the regions 1 to 5 can get the nucleic acid based diagnosis at the regional hub 60 that is disposed in the relevant region.
  • Results obtained by carrying out the nucleic acid based diagnosis at the regional hub 60 are delivered to the control center 40 illustrated in FIG. 1.
  • the delivery method may be any one of a network, a post, a person, or a vehicle.
  • the regional hub 60 is not disposed. Living bodies who live in the other regions 6 and 7 do not get the nucleic acid based diagnosis in the relevant region. Of course, the living bodies who live in the other regions 6 and 7 migrate to the regions 1 to 5 where the regional hub 60 is disposed, they can get the nucleic acid based diagnosis.
  • FIG. 2 a situation in which the mobile structure 10 for diagnosis according to the first embodiment is disposed in the remaining regions 6 and 7 is conceptually illustrated.
  • the regional hub 60 is disposed in some regions 1 to 5 among the plurality of regions 1 to 7, which is the same as in FIG. 1. However, unlike FIG. 1, it is illustrated in FIG. 2 that the mobile structure 10 for diagnosis is disposed in the remaining regions 6 and 7.
  • the mobile structure 10 for diagnosis refers to a structure in which facilities and environments for the nucleic acid based diagnosis are provided.
  • This mobile structure 10 for diagnosis may be connected with any vehicle. In this case, the movement is possible.
  • the mobile structure 10 for diagnosis is moved to and disposed in the regions 6 and 7 where the regional hub 60 is not disposed, the living bodies who live in the relevant regions 6 and 7 are allowed to get the nucleic acid based diagnosis in the region where they own live without moving to another region.
  • the nucleic acid based diagnosis can be carried out through the mobile structure 10 for diagnosis in the region where the facilities or environments for the nucleic acid based diagnosis are not provided.
  • detection of specific illnesses or diseases can be conducted without omitted regions throughout the world or the country.
  • overall monitoring for specific illnesses or diseases can be facilitated, as well as preventive measures against epidemics can be carefully established when the epidemics are generated.
  • FIG. 3 A perspective view for the appearance of the mobile structure 10 for diagnosis according to the first embodiment is illustrated in FIG. 3. Left and right side views for the appearance of the mobile structure 10 for diagnosis according to the first embodiment are illustrated in FIGS. 4 and 5. Right side views for the appearance of the mobile structure 10 for diagnosis according to the first embodiment are illustrated in FIGS. 6 and 7.
  • the mobile structure 10 for diagnosis can be connected to a vehicle 20.
  • each of the mobile structure 10 for diagnosis and the vehicle 20 may be provided with components such as ligaments which mutually enable ligament.
  • this vehicle 20 may be a vibration-free vehicle.
  • the mobile structure 10 for diagnosis includes a housing 100 in which a space is provided.
  • This housing 100 includes a steel structure 110.
  • a material such as steel as well as a material containing an antibacterial or antiviral component. Due to this material, a disease germ that has a possibility of existing within the housing 100 can penetrate the housing 100 to move to the outside, and vice versa.
  • a sunlight collector plate may be disposed above the housing 100 (not illustrated).
  • a solar power generator may be disposed inside the housing 100 (not illustrated). Through the sunlight collector plate and the photovoltaic power generator, electric power generated through sunlight may be provided to devices disposed inside the mobile structure 10 for diagnosis.
  • the housing 100 is provided with a plurality of opening sections. Various components for given purposes are disposed at each of the opening sections.
  • an inlet part 300 may be disposed at any one of the plurality of opening sections provided to the housing 100.
  • the inlet part 300 is a component that provides the incoming path along which the raw sample comes into the exterior of the mobile structure 10 for diagnosis.
  • a first entrance part 500, a second entrance part 600, at least one window part 151, an outdoor fan-purpose door part 161, a first servant space-purpose door part 171, a second servant space-purpose door part 181, and a waste withdrawal door part 191 may be disposed in any one of the plurality of opening sections.
  • the first entrance part 500 is a component that is used by a person who intends to treat a raw sample when moving between the exterior section and a pretreatment space.
  • a traffic line along which the person who intends to treat a raw sample moves will be referred to as a first entrance path. Meanwhile, a specific embodiment of the first entrance part 500 will be described below in greater detail.
  • the second entrance part 600 is a component that is used by a person who intends to treat the pretreated sample when moving between the exterior section and the analysis space.
  • a traffic line along which the person who intends to treat the pretreated sample moves will be referred to as a second entrance path.
  • a specific embodiment of the second entrance part 600 will be described below in greater detail.
  • the window part 151 indicates a window made of an optically transparent glass, and, as illustrated, at least one window part may be disposed. Persons (or operators) within the housing 100 can check exterior situations through the window part 151. Moreover, this window part 151 makes it possible to enter light toward the interior of the housing 100. At least one window part 151 may be disposed on the side of the aforementioned pretreatment space and the aforementioned analysis space. In this case, sizes and shapes of the window parts 151 may be different from each other. However, such sizes and shapes are not interpreted as being limited by being illustrated in the drawings.
  • the outdoor fan-purpose door part 161 is a door for the outdoor unit to be disposed in the second servant space.
  • the outdoor fan-purpose door part 161 is opened when the outdoor unit is operated. Through the opening section that is opened in this way, heat or moisture inside a pretreatment space 700 and an analysis space 800, which is absorbed at an outdoor unit 920, can be discharged outside.
  • the first servant space-purpose door part 171 is a component that is used for entry of a person or a specific object between the first servant space and the exterior section
  • the second servant space-purpose door part 181 is a component that is used for entry of a person or a specific object between the second servant space and the exterior section.
  • Each of the first servant space-purpose door part 171 and the second servant space-purpose door part 181 may be, but not limited to, a hinged or sliding type door.
  • the waste withdrawal door part 191 is a component that is used when wastes generated from the pretreatment space is withdrawn to the exterior section. Through this waste withdrawal door part 191, a variety of wastes such as wastes, pipette tips or swaps which are generated by unpacking raw samples, can be withdrawn to the exterior section.
  • the waste withdrawal door part 191 includes an intermediate chamber, an exterior-side door part, and a pretreatment space-side door part.
  • the pretreatment space-side door part is disposed so as to open/close the opening section formed in the housing 100.
  • the intermediate chamber is formed outside the housing 100 by a partition wall of which a side surface is formed.
  • the intermediate chamber may be formed under or aside the exterior surface of the housing 100.
  • the exterior-side door part is disposed to open/close the connection passage between the intermediate chamber and the exterior section.
  • the wastes contained in the intermediate chamber are stored while dropping to a separate waste disposal bin disposed on the bottom outside the mobile structure 10 for diagnosis0.
  • the components that are previously described that they can be disposed in the plurality of opening sections respectively are merely illustrative. Therefore, some of the previously described components may be disposed at positions different form the previously described positions in some cases, or at positions at which the opening sections are located. Alternatively, unmentioned components may be disposed at the opening sections.
  • the mobile structure 10 for diagnosis includes the housing 100, a partitioning part 200, an inlet part 300, a delivery part 400, a first entrance part 500, and a second entrance part 600.
  • the mobile structure 10 for diagnosis may further include additional components, which will be described later.
  • the housing 100 will be described.
  • the steel structure 110 forming the housing 100 is illustrated.
  • a window part 151 an outdoor fan-purpose door part 161, a first servant space-purpose door part 171, a second servant space-purpose door part 181, and a waste withdrawal door part 191.
  • the housing 100 and the components 151, 161, 171, 181, 191 included or disposed in the housing 100 the foregoing descriptions thereof will be referred to.
  • the partitioning part 200 is configured to partition and divide the internal space of the housing 100 into a plurality of subspaces. Referring to FIG. 8, the internal space of the housing 100 may be divided into the pretreatment space 700, the analysis space 800, a first servant space 900, and a second servant space 1000.
  • the partitioning part 200 includes a wall part 210, a transparent part 220, and a curtain part 230, but is not limited thereto.
  • the wall part 210 refers to a wall.
  • the wall includes a material preventing the penetration of air, moisture, pathogens, or the like therethrough.
  • the wall part 210 is disposed between the pretreatment space 700 and the first servant space 900 and between the pretreatment space 700 and the analysis space 800. The movement of air, pathogens, or the like through the wall part 210 between these spaces is prevented.
  • At least one open area may be provided in the wall part 210.
  • the transparent part 220 may be disposed in some of these open areas.
  • the transparent part 220 refers to an optically transparent component.
  • the transparent part 220 may include a glass window.
  • a person in one space of the pretreatment space and the analysis space may identify a person or a processing situation in the counterpart space through the transparent part 220.
  • the delivery part 400 may be disposed on some of the open areas. The delivery part 400 will be described later.
  • the curtain part 230 is one of means for diving the space, and may be referred to as a curtain.
  • the analysis space 800 and the second servant space 1000 are divided from each other by the curtain part 230.
  • a person in the second servant space 1000 may draw the curtain part 230 when changing clothes so that a person in the analysis space 800 cannot see him or her.
  • the inlet part 300 is configured to provide an inlet path for a raw sample from the outside to the pretreatment space 700. That is, a sample collected from a sample provider outside may be packed and introduced to the pretreatment space 700 through the inlet part 300.
  • the raw sample is introduced to the pretreatment space 700 from the outside through the inlet part 300, whereas an operator handling the raw sample introduced in this manner moves between the outside and the pretreatment space 700 through the first entrance part 500. That is, the introduction path for the raw sample and a movement path, through which the operator handling the introduced raw sample moves, do not overlap each other when viewed from above the mobile structure 10 for diagnosis (i.e., in a top view). Since the introduction path and the movement path do not overlap each other, the possibility of contamination between the raw sample and the operator may be reduced.
  • the inlet part 300 and a raw sample sealing part 710 (to be described later) disposed in the pretreatment space 700 may be connected to each other in a sealing manner.
  • the position of the inlet part 300 may be determined in consideration of the position of the raw sample sealing part 710 in the pretreatment space 700.
  • the inlet part 300 may be disposed such that the inlet part 300 and the inlet part 300 face each other while being on both sides of the steel structure 110 of the housing 100, but is not limited thereto.
  • the concept of the present disclosure is not limited to the inlet part 300 and the raw sample sealing part 710 being connected to each other in a sealing manner.
  • the inlet part 300 and the raw sample sealing part 710 may be disposed in the pretreatment space 700 to be spaced apart from while not being connected to each other.
  • the delivery part 400 may be disposed in an open area of the wall part 210 as described above.
  • the delivery part 400 is configured to form a path through which the pretreatment sample is delivered from the pretreatment space 700 to the analysis space 800. That is, the pretreatment sample pretreated in the pretreatment space 700 may be delivered to the analysis space 800 through the delivery part 400.
  • the pretreatment sample is not delivered by an operator moving from the pretreatment space 700 to the analysis space 800.
  • the pretreatment sample is delivered through the delivery part 400 without requiring the operator to move from the pretreatment space 700 to the analysis space 800.
  • the possibility of contamination caused by the operator moving between the spaces may be reduced.
  • each of the subspaces such as the first servant space 900, the second servant space 1000, the pretreatment space 700, and the analysis space 800, will be described.
  • an atmospheric pressure adjustment part 910, an outdoor fan-purpose door part 920, and a thermostat 930 are disposed in the first servant space 900, but the present disclosure is not limited thereto.
  • the atmospheric pressure adjustment part 910 is configured to generate various levels of gas pressure, i.e., atmospheric pressure.
  • the level of the atmospheric pressure generated may have at least one.
  • the atmospheric pressure adjustment part 910 may generate various levels of atmospheric pressure (i.e., positive pressure or a negative pressure) different from an external atmospheric pressure n times 2.5pa (where n is an integer).
  • the atmospheric pressure adjustment part 910 include an atmospheric pressure sensing unit to sense an outside atmospheric pressure or an atmospheric pressure in a space to which the atmospheric pressure is provided, an atmospheric pressure generating unit to generate various levels of atmospheric pressure, pipe members, such as ducts, to deliver or provide various levels of atmospheric pressure to different spaces, and the like.
  • pipe members such as ducts
  • a negative pressure or a positive pressure generated by the atmospheric pressure generating unit of the atmospheric pressure adjustment part 910 is supplied to the internal space of the raw sample sealing part 710 or the pretreatment space 700 through the pipe members.
  • the negative pressure or the positive pressure may be provided to an intermediate chamber 310 of the inlet part 300 and an intermediate chamber 410 of the delivery part 400 or the analysis space 800.
  • the negative pressure When the negative pressure is provided, air in each of the spaces is drawn toward the atmospheric pressure adjustment part 910.
  • the pipe members may extend into respective spaces while being separated from each other. thus, the possibility of cross contamination caused by common use of the pipe members may be removed or reduced.
  • air may be drawn from each space by an outdoor fan 920 to be described later or the thermostat 930. Likewise, the risk of movement of air in each space and pathogens that may be contained in the air to another space may be reduced.
  • the atmospheric pressure adjustment part 910 may include an antibacterial filter.
  • the atmospheric pressure adjustment part 910 may include, for example, a HEPA filter, but is not limited thereto.
  • air drawn to the atmospheric pressure adjustment part 910 from each space due to the negative pressure applied is discharged to the outside after having passed through the antibacterial filter.
  • Pathogens that may be contained in the air drawn from each space are filtered out by the antibacterial filter.
  • the cross-section of the HEPA filter may be referred to as having a honeycomb structure comprised of a plurality of hexagons butted to each other. This structure may maximize the area of the antibacterial filter which the air comes into contact with, thereby maximizing antibacterial ability of the antibacterial filter.
  • the atmospheric pressure adjustment part 910 may include an alarm unit to generate a warning signal when the level of an atmospheric pressure sensed by the atmospheric pressure sensing unit exceeds a reference value.
  • the atmospheric pressure generating unit may control the atmospheric pressure generating unit so that the atmospheric pressure supplied to each space meets the reference value.
  • the outdoor fan 920 is configured to control the temperature or moisture of the pretreatment space 700 and the analysis space 800.
  • the outdoor fan 920 may have a function similar to that included in an air conditioner system or a dehumidifier.
  • the outdoor fan 920 may be disposed adjacent to the outdoor fan-purpose door part 161.
  • the outdoor fan 920 When the outdoor fan 920 is operated, the outdoor fan-purpose door part 161 is opened, and the outdoor fan 920 discharges at least one of heat and moisture absorbed from inside the pretreatment space 700 and the analysis space 800 through the opened door part.
  • the outdoor fan 920 may include the antibacterial filter included in the atmospheric pressure adjustment part 910. Pathogens that may be contained in the air drawn from the pretreatment space 700 or the analysis space 800 may be filtered out by the antibacterial filter, and thus the air without pathogens may be discharged to the outside.
  • the thermostat 930 is configured to control the temperature of the pretreatment space 700 and the analysis space 800.
  • the second servant space 1000 accommodates a power generator 1010, an emergency power supply 1011, and a reagent refrigerator 1012, but is not limited thereto.
  • the power generator 1010 is configured to generate electric power.
  • the power generator 1010 is supplied with fuel, such as diesel. As the fuel supplied is combusted, the rotor of the power generator 1010 is rotated, thereby generating electric power using rotating force of the rotor.
  • the power generator 1010 may be disposed adjacent to the second servant space-purpose door part 181.
  • the power generator 1010 may be taken out from the second servant space 1000 through the opened door part, and then may be operated outside.
  • the power generator 1010 is operated outside instead of in the second servant space 1000, operators or a variety of devices in the mobile structure 10 for diagnosis may be less influenced by noise or vibration resulting from power generation.
  • an embodiment in which the power generator 1010 is disposed in the second servant space 1000 instead of being disposed outside is not excluded from the present disclosure.
  • the second servant space-purpose door part 181 may be opened or closed about the hinge. Differently from FIG. 7, the second servant space-purpose door part 181 may be opened or closed in a sliding manner.
  • the emergency power supply 1011 is a component also referred to as an uninterruptible power supply (UPS).
  • the emergency power supply 1011 may provide emergency power before the power generator 1010 is operated when constant external power fails.
  • the reagent refrigerator 1012 is a generator storing reagents.
  • the reagent refrigerator 1012 is connected to the power generator 1010, the emergency power supply 1011, and a constant external power source (not shown).
  • the constant external power source malfunctions or fails, the reagent refrigerator 1012 may be immediately operated to use electric power supplied by the emergency power supply 1011.
  • the reagent refrigerator 1012 may operate using electric power supplied by the power generator 1010.
  • the reagent refrigerator 1012 may be driven at a temperature of about -20°C.
  • the pretreatment space 700 accommodates the raw sample sealing part 710, the dispenser 730, the nucleic acid extraction device 720, and the sample refrigerator 740, but is not limited thereto.
  • the raw sample sealing part 710 is configured to pretreat the packed raw sample introduced through the inlet part 300.
  • the dispenser 730 is also referred to as a liquid handling device.
  • the dispenser 730 may be an automated liquid handling device that is automatically operated by a computer program or a liquid handling device that is manually operated by an operator.
  • the configuration of such a liquid handling device is well known in the art, and thus a description thereof will be omitted.
  • the nucleic acid extraction device 720 is configured to receive the mixed sample from the dispenser 730 and extract nucleic acid from the sample.
  • the dispenser 730 and the nucleic acid extraction device 720 are disposed in the pretreatment space 700.
  • the nucleic acid extraction operation is performed. Specifically, the dispenser 730 mixes the sample with a nucleic acid extraction reagent, and the nucleic acid extraction device 720 extracts nucleic acid from the sample.
  • the sample refrigerator 740 is a refrigerator that stores the remaining raw samples, among the raw samples unpacked and deactivated by the raw sample sealing part 710, except for the raw samples provided to the dispenser 730.
  • the sample refrigerator 740 may be driven to maintain a temperature of about -70°C.
  • the sample refrigerator 740 is connected to the power generator 1010, the emergency power supply 1011, and a constant external power source (not shown).
  • the constant external power source malfunctions or fails, the reagent refrigerator 1012 may be immediately operated to use electric power supplied by the emergency power supply 1011. After the power generator 1010 starts to operate stably, the reagent refrigerator 1012 may operate using electric power supplied by the power generator 1010.
  • the analysis space 800 accommodates a dispenser 810, an additional operation device 820, an analysis device 830, and a computer 890, but is not limited thereto.
  • the dispenser 810 has the same name as the dispenser disposed in the pretreatment space 700, the dispenser 810 performs a different operation from the dispenser disposed in the pretreatment space 700.
  • the dispenser 810 and the additional operation device 820 perform the above-described setup operation. Described in detail, for example, the dispenser 810 mixes the sample, delivered from the delivery part 400, with a reagent. In addition, the additional operation device 820 performs an operation related to an IC or PC.
  • the analysis device 830 performs the nucleic acid detection operation.
  • the computer 890 reads a result received from the analysis device 830, the result being obtained from the operation performed by the analysis device 830.
  • the computer 890 may detect, for example, whether or not a pathogen is present in the sample from the result of the operation performed by the analysis device 830.
  • the detected result may be stored in the form of data, and be transmitted to a control center 40 through a network by way of a regional base 60 or directly through the network.
  • FIG. 13 is a perspective diagram illustrating an inlet part housing open area 120 formed in the housing 100 and the inlet part 300 disposed in the inlet part housing open area 120 in the mobile structure for diagnosis according to the first embodiment.
  • FIG. 13 is merely an example, and the concept of the present disclosure shall not be interpreted as being limited to the illustration of FIG. 13.
  • FIG. 13 (a) illustrates the wall part 110 of the housing 100 and the inlet part housing open area 120 formed in the wall part 110.
  • the inlet part 300 is not illustrated.
  • FIG. 13 (b) illustrates a situation in which the inlet part housing open area 120 is closed by a door part 302 of the inlet part 300. In this situation, the movement of air, disease-causing viruses or bacteria, and the like between the outside and the pretreatment space 700 is blocked.
  • FIG. 13 (c) illustrates a situation in which a portion of the inlet part housing open area 120 is closed by the door part 302 and the remaining portion of the inlet part housing open area 120 is opened. That is, the door part 302 is moved upward by sliding from the position in FIG. 13 (b), thereby opening a portion of the inlet part housing open area 120.
  • the inlet part 300 in the present embodiment may include a UV emitter and an air curtain.
  • the UV emitter emits UV radiation and the air curtain blows air toward the inlet part housing open area 120, respectively, as indicated with arrows in FIG. 13 (c-1).
  • the UV radiation emitted, an effect of sterilizing the air introduced from the outside may be obtained, and flow of air between the outside and the pretreatment space 700 may be blocked by the blown air. Consequently, it is possible to reduce the risk that pathogens which may be contained in the air may enter the pretreatment space 700 from the outside.
  • FIG. 13 (c-2) also illustrates a situation in which only a portion of the inlet part housing open area 120 is closed by the door part 302 and the remaining portion of the inlet part housing open area 120 is opened. That is, the door part 302 may rotate about a top horizontal shaft from the position in FIG. 13 (b), thereby opening a portion of the inlet part housing open area 120.
  • the situation in FIG. 13 (c-2) is different from the situation in FIG. 13 (c-1) in that the door part 302 rotates about the hinge.
  • FIG. 14 is a perspective diagram illustrating another example of the inlet part 300 disposed in the inlet part housing open area 120 in the mobile structure for diagnosis according to the first embodiment.
  • FIG. 14 is merely an example, and the concept of the present disclosure shall not be interpreted as being limited to the illustration of FIG. 14.
  • the inlet part 300 includes the intermediate chamber 310, the outside door part 311, and the pretreatment space-side door part 312, but is not limited thereto.
  • the intermediate chamber 310 refers to a space in which a raw sample is to be placed.
  • the intermediate chamber 310 may be defined by a wall of a side surface of the space, the outside door part 311, and the pretreatment space-side door part 312.
  • the outside door part 311 is configured to open and close the connection path between the outside and the intermediate chamber 310.
  • the pretreatment space-side door part 312 is configured to open and close the connection path between the intermediate chamber 310 and the pretreatment space 700.
  • Each of the outside door part 311 and the pretreatment space-side door part 312 may contain an optically transparent material. Thus, an operator or the like may visually determine whether or not the raw sample is placed in the intermediate chamber 310.
  • the inlet part 300 may further include a UV emitter (not shown) to emit UV radiation into the intermediate chamber 310. Due to the UV radiation emitted, an effect of sterilizing the air introduced from the outside may be obtained. Consequently, it is possible to reduce the risk that pathogens which may be contained in the air introduced from the outside may enter the mobile structure 10 for diagnosis through the inlet part 300.
  • a UV emitter not shown
  • the intermediate chamber 310 of the inlet part 300 may be connected to the atmospheric pressure adjustment part 910.
  • the atmospheric pressure adjustment part 910 adjusts the internal atmospheric pressure of the intermediate chamber 310 with respect to the external atmospheric pressure and the internal atmospheric pressure of the pretreatment space 700.
  • the atmospheric pressure adjustment part 910 may adjust the internal atmospheric pressure of the intermediate chamber 310 to be lower than the external atmospheric pressure and higher than the internal atmospheric pressure of the pretreatment space 700.
  • the inlet part 300 may further include a door opening/closing adjustment part 340.
  • the door opening/closing adjustment part 340 is configured to adjust the opening and closing of the door parts 311 and 312 so that the outside door part 311 and the pretreatment space-side door part 312 are not opened at the same time.
  • the door opening/closing adjustment part 340 may be implemented electronically or mechanically. Irrespective of whether the door opening/closing adjustment part 340 is implemented electronically or mechanically, the door opening/closing adjustment part 340 includes a door open/close detection part 342 detecting whether each of the doors 311 and 312 is opened or closed and a locking part 343, when one door is opened, locking the remaining door.
  • the door open/close detection part 342 may be a sensor detecting whether the door is opened or closed, and the locking part 343 may be a lock adjusting the locking of the door by receiving a signal from the sensor.
  • the door open/close detection part 342 and the locking part 343 may be implemented as a single device.
  • the configuration of the door opening/closing adjustment part 340 implemented mechanically is well known in the art, and thus a detailed description thereof will be omitted.
  • FIG. 16 is a perspective diagram illustrating a delivery part open area 212 provided in the wall part 210 of the partitioning part 200 and the delivery part 400 disposed in the delivery part open area 212 in the mobile structure for diagnosis according to the first embodiment.
  • FIG. 16 is merely an example, and the concept of the present disclosure shall not be interpreted as being limited to the illustration of FIG. 16.
  • FIG. 16 (a) illustrates the wall part 210 of the partitioning part 200 and the delivery part open area 212 formed in the wall part 210.
  • a door part 402 of the delivery part 400 to be described later is not shown.
  • FIG. 16 (b) illustrates a situation in which the delivery part open area 212 is closed by the door part 402 of the delivery part 400. In this situation, the movement of air, disease-causing germs or bacteria, and the like between the pretreatment space 700 and the pretreatment space 700 is blocked.
  • FIG. 16 (c-1) illustrates a situation in which only a portion of the delivery part open area 212 is closed by the door part 402 and the remaining portion of the delivery part open area 212 is opened. That is, the door part 402 is moved upward by sliding from the position in FIG. 16 (b), thereby opening a portion of the delivery part open area 212.
  • the delivery part 400 in the present embodiment may include a UV emitter and an air curtain.
  • the UV emitter emits UV radiation and the air curtain blows air toward the delivery part open area 212, respectively, as indicated with arrows in FIG. 16 (c-1).
  • the UV radiation emitted, an effect of sterilizing the air introduced from the outside may be obtained, and flow of air between the pretreatment space 700 and the analysis space 800 may be blocked by the blown air. Consequently, it is possible to reduce the possibility of contamination caused by flow of air between the pretreatment space 700 and the analysis space 800 through the opened space.
  • FIG. 16 (c-2) also illustrates a situation in which only a portion of the delivery part open area 212 is closed by the door part 402 and the remaining portion of the delivery part open area 212 is opened. That is, the door part 402 may rotate about the hinge, thereby opening a portion of the delivery part open area 212.
  • the situation in FIG. 16 (c-2) is different from the situation in FIG. 16 (c-1) in that the door part 402 is opened in a different manner.
  • FIG. 17 is a perspective diagram illustrating another example of the delivery part open area 212 provided in the wall part 210 of the partitioning part 200 and the delivery part 400 disposed in the delivery part open area 212 in the mobile structure for diagnosis according to the first embodiment.
  • FIG. 17 is merely an example, and the concept of the present disclosure shall not be interpreted as being limited to the illustration of FIG. 17.
  • the delivery part 400 includes the intermediate chamber 410, a pretreatment space-side door part 411, and an analysis space-side door part 412, but is not limited thereto.
  • the intermediate chamber 410 refers to a space in which a raw sample is to be placed.
  • the intermediate chamber 410 may be defined by a wall of a side surface of the space, as well as the pretreatment space-side door part 411 and the analysis space-side door part 412 to be described below.
  • the pretreatment space-side door part 411 is configured to open and close the connection path between the pretreatment space 700 and the intermediate chamber 410.
  • the analysis space-side door part 412 is configured to open and close the connection path between the intermediate chamber 410 and the analysis space 800.
  • Each of the pretreatment space-side door part 411 and the analysis space-side door part 412 may contain an optically transparent material. Thus, an operator or the like may visually determine whether or not the raw sample is placed in the intermediate chamber 410.
  • the delivery part 400 may further include a UV emitter (not shown) to emit UV radiation into the intermediate chamber 410. Due to the UV radiation emitted, an effect of sterilizing the air introduced from the outside may be obtained. Consequently, it is possible to reduce the risk of pathogens which may be contained in the air that will be introduced to the analysis space 800 from the pretreatment space 700.
  • a UV emitter not shown
  • the intermediate chamber 410 of the delivery part 400 may be connected to the atmospheric pressure adjustment part 910.
  • the atmospheric pressure adjustment part 910 adjusts the internal atmospheric pressure of the intermediate chamber 410 with respect to the internal atmospheric pressure of the pretreatment space 700 and the internal atmospheric pressure of the analysis space 800.
  • FIG. 18 is a table illustrating example internal atmospheric pressures of the intermediate chamber 410 adjusted using the atmospheric pressure adjustment part 910. A description will be given with reference to FIG. 18. First, the internal atmospheric pressure of the pretreatment space 700 will be indicated with A, the internal atmospheric pressure of the analysis space 800 will be indicated with B, and the internal atmospheric pressure of the intermediate chamber 410 will be indicated with x. In addition, the internal atmospheric pressure A of the pretreatment space 700 will be referred to as negative, compared to the internal atmospheric pressure B of the analysis space 800.
  • the atmospheric pressure adjustment part 910 may set the internal atmospheric pressure x of the intermediate chamber 410 to be lower than each of the internal atmospheric pressures A and B. This may be a situation in which the pretreatment sample is placed inside the intermediate chamber 410.
  • the atmospheric pressure adjustment part 910 may adjust the internal atmospheric pressure x of the intermediate chamber 410 to be the same as the internal atmospheric pressure B of the analysis space-side door part 412.
  • the atmospheric pressure adjustment part 910 may adjust the internal atmospheric pressure x of the intermediate chamber 410 to be the same as the internal atmospheric pressure A of the pretreatment space-side door part 411.
  • both the pretreatment space-side door part 411 and the analysis space-side door part 412 cannot be opened at the same time by a door opening/closing adjustment part 440.
  • the door opening/closing adjustment part 440 will be described as follows.
  • the delivery part 400 may further include the door opening/closing adjustment part 440 illustrated in FIG. 19.
  • the door opening/closing adjustment part 440 is configured to adjust the opening and closing of the door parts 411 and 412 so that both the outside door part 411 and the pretreatment space-side door part 412 are not opened at the same time.
  • the door opening/closing adjustment part 440 may be implemented electronically or mechanically. Irrespective of whether the door opening/closing adjustment part 440 is implemented electronically or mechanically, the door opening/closing adjustment part 440 includes a door open/close detection part 442 detecting whether each of the doors 411 and 412 is opened or closed and a locking part 443, when one door is opened, locking the remaining door.
  • the door open/close detection part 442 may be a sensor detecting whether the door is opened or closed, and the locking part 443 may be a lock adjusting the locking of the door by receiving a signal from the sensor.
  • the door open/close detection part 442 and the locking part 443 may be implemented as a single device.
  • the configuration of the door opening/closing adjustment part 440 implemented mechanically is well known in the art, and thus a detailed description thereof will be omitted.
  • the mobile structure 10 for diagnosis may further include components not described hereinabove.
  • the mobile structure 10 for diagnosis may include a vibration detection part 1100, a calibration alarm part 1101, a vibration reducing part 1102, a balance detection part 1103, and a balance adjustment part 1104, but is not limited thereto.
  • the vibration detection part 1100 refers to a sensor attached to the mobile structure 10 for diagnosis or each of devices provided inside mobile structure 10 for diagnosis to detect vibration.
  • the vibration detection part 1100 may be implemented as a piezoelectric sensor.
  • the vibration detection part 1100 may include, for example, a memory recording or storing the magnitude of the detected vibration, the duration of the detected vibration, and the like. A type of numerical value may be calculated on the basis of the magnitude, the duration, and the like.
  • the calibration alarm part 1101 is an alarm notifying that calibration of the devices disposed inside the mobile structure 10 is required.
  • the calibration alarm part 1101 may be a means for generating a warning signal using sound, an image, or the like.
  • the calibration alarm part 1101 may periodically generate the warning signal. There may be a variety of periods, such as 1 week, 1 month, 6 months, 1 year, and the like. The period may also be set or changed.
  • the calibration alarm part 1101 may generate a warning signal when the numerical value calculated by the vibration detection part 1100 exceeds a predetermined threshold value. For example, when the mobile structure 10 for diagnosis moves from one region to another region or an earthquake occurs in a region in which the mobile structure 10 for diagnosis is disposed, the vibration detection part 1100 may obtain a numerical value exceeding a reference value, and the calibration alarm part 1101 may generate the warning signal notifying that the calibration is required, on the basis of the numerical value obtained.
  • first entrance part 500 and the second entrance part 600 described above may be embodied in a variety of forms, in a manner similar to the inlet part 300.
  • each of the entrance parts 500 and 600 may be implemented as a door part opening and closing the open area provided in the housing 100.
  • a UV emitter, an air curtain, or the like may be disposed in a position in which the door part is provided.
  • the intermediate chamber may be disposed in an intermediate portion of each of the entrance parts 500 and 600, and the door parts may be disposed on both ends of the intermediate chamber.
  • the operator When an operator is required to enter the pretreatment space 700 from the outside, the operator opens the outside door part, enters the intermediate chamber, closes the outside door part, opens the pretreatment space-side door part, and then enters the pretreatment space 700.
  • the above operations are performed in the reverse order.
  • the width of variation of the atmospheric pressure, such as a negative pressure, formed in the pretreatment space 700 caused by the operator moving through the entrance part 500 may be reduced as compared to a situation in which no intermediate chamber is provided. The same applies to the entrance part 600.
  • FIG. 21 illustrates the above-described situation in which a sampling booth 30 and a regional base 60 are added to a plan diagram of the mobile structure 10 for diagnosis.
  • FIGS. 22 to 26 are snapshot virtual images illustrating situations that may actually occur in the mobile structure 10 for diagnosis.
  • a raw sample is collected from a sample provider 31 in the sampling booth 30.
  • the packed raw sample is delivered to a raw sample unpacking part 710 through the inlet part 300.
  • the raw sample unpacking part 710 serves to unpack and deactivate the sample.
  • Some of the samples processed in 3 are stored in a sample refrigerator 740, and the remaining samples are delivered to a dispenser 730.
  • the dispenser 730 performs a dispensing operation to the samples delivered.
  • a nucleic acid extraction device 720 extracts nucleic acid from the samples processed in 4. As a result, pretreatment samples including the extracted nucleic acid are obtained.
  • the pretreatment samples are delivered to a dispenser 810 through the delivery part 400.
  • the dispenser 810 mixes the pretreatment samples delivered from the delivery part 400 with a reagent.
  • An additional operation device 820 performs an operation related to an additional reagent.
  • the samples processed in 9 are delivered to an analysis device 830.
  • the analysis device 830 analyzes the samples delivered.
  • the analysis may include nucleic acid detection.
  • a result obtained by the analysis in 9 is transmitted to a computer 890.
  • the computer 890 derives a nucleic acid-based diagnostic result for the raw samples.
  • the derived nucleic acid-based diagnostic result may be transmitted to the control center 40 through the network 50 by way of the regional base 60 or to the control center 40 directly through the network 50.
  • FIG. 22 is a snapshot image illustrating a situation in which an operator enters the analysis space 800 by opening the second entrance part 600.
  • FIG. 23 is a snapshot image illustrating a situation in which the operator who has entered the second servant space 1000 is changing clothes by drawing the curtain part 230 in the second servant space 1000.
  • Such situations include a situation in which the operator enters the first entrance part 500 by opening the door part and a situation in which the operator changes clothes in a dressing space.
  • FIG. 24 is a snapshot image illustrating a situation in which a raw sample collected in the sampling booth 30 is being delivered to the inlet part 300 in a packed state.
  • FIG. 25 is a snapshot image illustrating a situation in which the raw sample delivered to the raw sample unpacking part 710 through the inlet part 300 is being unpacked and deactivated in the raw sample unpacking part 710.
  • the unpacking and deactivation may be performed while the raw sample unpacking part 710 is under a negative pressure.
  • FIG. 26 is a snapshot image illustrating a situation in which the pretreatment sample is being delivered from the pretreatment space 700 to the analysis space 800 through the delivery part 400.
  • FIG. 27 is a snapshot image illustrating a situation in which the additional operation device 820 of the analysis space 800 performs an additional operation to the pretreatment sample and the analysis device 830 analyzes the pretreatment sample to which the additional operation has been performed.
  • FIG. 28 is a flowchart illustrating the process flow illustrated in FIG. 21.
  • FIG. 28 is merely an example, and the concept of the present disclosure shall not be interpreted as being limited to the illustration of FIG. 28.
  • a raw sample is collected from the sample provider 31 in the sampling booth 30.
  • the raw sample collected in S100 is in a packed state and delivered to the raw sample unpacking part 710 of the pretreatment space 700 through the inlet part 300 of the mobile structure 10 for diagnosis.
  • the raw sample unpacking part 710 unpacks and deactivates the raw sample.
  • the dispenser 730 performs a dispensing operation to the raw samples delivered.
  • the dispensing operation may include mixing each of the raw samples with a nucleic acid extraction reagent.
  • the nucleic acid extraction device 720 performs an operation of extracting a nucleic acid from the sample to which the mixing operation in S130 is completed. As a result, a pretreatment sample containing the extracted nucleic acid is obtained.
  • the pretreatment sample obtained in S140 is delivered to the analysis space 800 through the delivery part 400.
  • the dispenser 810 mixes the sample delivered from the delivery part 400 with a reagent.
  • the additional operation device 820 performs an operation related to an additional reagent (IC or PC).
  • the sample processed in S120 is delivered to the analysis device 830.
  • the analysis device 830 analyzes the analysis sample delivered.
  • the analysis operation may include a nucleic acid detection operation.
  • a result regarding completion of the analysis operation in S220 is transmitted to the computer 890.
  • the computer 890 derives a nucleic acid-based diagnosis result regarding the raw sample.
  • the derived nucleic acid-based diagnosis result may be transmitted to the control center 40 through the network 50 by way of the regional base 60 or to the control center 40 directly through the network 50.
  • nucleic acid-based diagnosis may be performed using the mobile structure for diagnosis.
  • a specific disease or illness can be detected throughout the world or the country without missing regions. Consequently, not only can overall monitoring of specific diseases or disorders be easily performed, but also anti-epidemic measures can be thoroughly established in preparation of an outbreak of an infectious disease.
  • the introduction path through which the raw sample collected from the sample provider is introduced into the mobile structure for diagnosis
  • the movement path through which the operator handling the raw sample moves
  • the introduction path and the movement path do not overlap each other, the possibility of contamination between the raw sample and the operator may be reduced.
  • the raw sample is delivered by the delivery part, rather than by a person, in the pretreatment space in which the raw sample is pretreated and the analysis space in which the pretreatment sample is analyzed.
  • the delivery of air or pathogens between respective spaces can be minimized, thereby minimizing the risk of contamination or infection.
  • a calibration warning signal for the devices installed inside the mobile structure for diagnosis is generated.
  • the status of nucleic acid-based diagnosis devices designed to perform highly sophisticated/precise movements can be managed optimally, and thus an accurate nucleic acid-based diagnosis result can be derived.
  • nucleic acid extraction device 720 is disposed in the pretreatment space 720, and the dispenser 810 and the additional operation device 820 are disposed in the analysis space 800.
  • this illustration is only an example, and the concept of the present disclosure is not limited thereto.
  • nucleic acid extraction device 720 may be disposed in the pretreatment space 700.
  • all of the devices 720, 810, and 820 may be disposed in the analysis space 800.
  • the pretreatment sample refers to a sample subjected to the pretreatment operation, the nucleic acid extraction operation, and the setup operation
  • the analysis sample refers to a sample subjected to the analysis operation.
  • the pretreatment sample refers to a sample subjected to the pretreatment operation
  • the analysis sample refers to a sample subjected to the nucleic acid extraction operation, the setup operation, and the analysis operation.
  • FIGS. 29 to 31 are perspective diagrams illustrating a mobile structure 10 for diagnosis according to a second embodiment.
  • FIGS. 29 to 31 are merely an example, and the concept of the present disclosure shall not be interpreted as being limited to the illustration of FIGS. 29 to 31.
  • the mobile structure 10 for diagnosis according to the second embodiment includes the partitioning part 200, the inlet part 300, the delivery part 400, the first entrance part 500, and the second entrance part 600, but is not limited thereto.
  • the housing 100 according to the second embodiment is the same as the housing 100 according to the first embodiment. Thus, regarding the housing 100 according to the second embodiment, the description of the housing 100 according to the first embodiment will be referred to.
  • the second embodiment is different from the first embodiment in that the partitioning part 200 according to the second embodiment is disposed between the pretreatment space 700 and the analysis space 800.
  • the wall part 210 having the delivery part open area 212 is disposed between the pretreatment space 700 and the analysis space 800.
  • the open area 211 for the transparent part is not disposed between the pretreatment space 700 and the analysis space 800.
  • the first entrance part 500 and the second entrance part 600 are disposed on distal ends of the extension of the wall part 210.
  • the first entrance part 500 and the second entrance part 600 are components that operators use to enter or exit the pretreatment space 700 and the analysis space 800.
  • the object and use of the first entrance part 500 and the second entrance part 600 are the same as those of the first embodiment.
  • the positions of the first entrance part 500 and the second entrance part 600 are different from those of the first embodiment.
  • the first entrance part 500 and the second entrance part 600 according to the first embodiment are disposed in positions spaced apart from each other, whereas the first entrance part 500 and the second entrance part 600 according to the second embodiment are disposed in positions in contact with each other.
  • first entrance part 500 and the second entrance part 600 are configured as separate components and are blocked from each other by a wall. Thus, even in the case in which both the door of the first entrance part 500 and the door of the second entrance part 600 are opened at the same time, there is low possibility that air or pathogens may be delivered from the pretreatment space 700 to the analysis space 800 or vice versa.
  • the mobile structure 10 for diagnosis according to the second embodiment is the same as the mobile structure 10 for diagnosis according to the first embodiment except for the above-described components, and thus descriptions of the same features will be omitted.
  • the sample collection space may be disposed inside the mobile structure 10 for diagnosis.
  • the partitioning part 200 may divide the internal space of the housing 100 into a sample collection space, the pretreatment space 700, the analysis space 800, the first servant space 900, and the second servant space 1000.
  • the inlet part 300 having the same structure as described above may be disposed between the sample collection space and the pretreatment space 700.
  • the sample collection space may be provided with a door allowing entrance to and egress from the sample collection space. More specifically, a door through which a sample provider enters and exits, a first space for the sample provider, a second space for a sample collector, a partitioning member separating the first space and the second space from each other, a glove box used by the sample collector in the second space to obtain a sample from the sample provider in the first space, and the like may be disposed in the sample collection space.
  • FIGS. 32 to 35 illustrate portions of an internal structure of a mobile structure for diagnosis according to a third embodiment.
  • a front room 591 i.e., an anterior room, is illustrated inside the mobile structure 10 for diagnosis.
  • the front room 591 serves to block flow of external air entering the pretreatment space 700 through the first entrance part 500 so that air does not leak from the pretreatment space 700 through the first entrance part 500 even in the case in which the first entrance part 500 is opened.
  • the front room 591 causes the negative pressure in the pretreatment space 700 to be maintained irrespective of whether the first entrance part 500 is opened or closed.
  • the first entrance part 500 is a means for opening and closing the housing open area 120, and thus may be referred to as an "housing opening/closing part" in the third embodiment.
  • the first entrance part 500 will be referred to by name.
  • the front room 591 is disposed in the pretreatment space 700 while being connected to a peripheral portion of the housing open area 120 so as to seal the housing open area 120, illustrated in FIG. 13, with respect to the pretreatment space 700.
  • a space i.e., an internal space
  • the size of the internal space may be changed or can be varied. Comparing FIGS. 33 and 34 with FIG. 35, the front room 591 may slide along the ceiling of the pretreatment space 700. When the state of the front room 591 that has slid is as illustrated in FIGS. 33 and 34, the size of the front room 591 in the pretreatment space 700 is maximized. Even at this time, the front room 591 also serves to block flow of air between the pretreatment space 700 and the first entrance part 500.
  • the size of the front room 591 in the pretreatment space 700 is minimized. Even at this time, the front room 591 blocks flow of air between the pretreatment space 700 and the first entrance part 500.
  • the front room 591 is provided by the front room part 5911 illustrated in FIGS. 33 to 35.
  • the front room part 5911 may include a guide part 59111 allowing the front room 591 to slide, a wall part 59112 defining an internal space inside the front room 591, a fixing member (not shown) by which the wall part 59112 is hung on the guide part 59111, a sealing-connecting part 59113 connecting one end of the wall part 59112 to a peripheral portion of the housing open area 120, and a front room opening/closing part 59114 opening and closing the front room open area formed in the wall part 59112, but is not limited thereto.
  • the guide part 59111 has a rail formed along a bar-shaped body forming a guide.
  • the guide part 59111 guides a predetermined object to move along the rail.
  • the guide part 59111 is comprised of two members, but is not limited thereto.
  • the guide part 59111 may be embodied as a single member or be comprised of three or more members.
  • the length of the guide part 59111 may be changed.
  • the guide part 59111 may be provided with a joint or the like, by which the length of the guide part 59111 may be adjusted.
  • the wall part 59112 defines an enclosed space therein.
  • the material of the wall part 59112 may include a material preventing the penetration of air, moisture, pathogens, or the like therethrough, but is not limited thereto.
  • the wall part 59112 may be optically transparent or semitransparent.
  • the wall part 59112 may include a material suitable to a foldable structure that may be folded and unfolded.
  • the wall part 59112 may be formed of a hard material or a soft material, such as urethane.
  • a UV emitter or a negative pressure providing part may be provided inside the wall part 59112.
  • UV radiation may be emitted into the front room or a negative pressure may be provided into the front room.
  • the sealing-connecting part 59113 is a component connecting the wall part 59112 to the housing open area 120 in a sealing manner, as indicated with dotted lines in FIGS. 33 and 34.
  • the sealing-connecting part 59113 may include Velcro tape.
  • the sealing-connecting part 59113 may also be referred to as portions of the wall part 59112 sealed to peripheral portions of the housing open area 120 using an adhesive or the like, but is not limited thereto.
  • the fixing member is a means for hanging the wall part 59112 on the guide part 59111.
  • the fixing member may be a component that may slide along the rail while being hung on the rail.
  • the front room opening/closing part 59114 is configured to open and close the front room open area of the wall part 59112.
  • the front room opening/closing part 59114 serves as an entrance through which an operator exits the pretreatment space 700 through the front room 591 and the first entrance part 500 or enters the pretreatment space 700 through the front room 591 by way of the first entrance part 500.
  • FIG. 34 illustrates the opened shaped of the front room opening/closing part 59114.
  • the shape of the front room opening/closing part 59114 is not limited to the shape illustrated in the figures, but may a circular shape, an elliptical shape, a triangular shape, or the like.
  • the front room open area formed in the wall part 59112 may be positioned in a side portion of the wall part 59112 differently from the front room open area illustrated in FIGS. 33 to 35, but is not limited thereto.
  • the front room opening/closing part 59114 may be opened and closed using a magnet, Velcro tape, a zipper, or the like.
  • the wall part 59112 may have another front room open area in addition to the front room open area illustrated in FIG. 34.
  • the front room open area may be provided in a position opposite the front room open area illustrated in FIG. 34.
  • the front room open area may be provided in a direction facing the first entrance part 500 in FIG. 33.
  • the front room part 5911 may further include an opening/closing part to open and close the other front room open area. When the opening/closing part opens or closes the other front room open area, the internal space of the front room may be constantly closed irrespective of the first entrance part 500.
  • the front room 591 is disposed as illustrated in FIG. 33.
  • the front room opening/closing part 59114 is closed.
  • air in the pretreatment space 700 may not exit through the first entrance part 500 or external air may not enter the pretreatment space 700 through the first entrance part 500, because the entrance or exit of air is blocked by the front room 591 even when the first entrance part 500 is opened.
  • the pretreatment space 700 is maintained in a negative pressure, the negative pressure of the pretreatment space 700 may be maintained irrespective of whether or not the first entrance part 500 is opened.
  • the size of the front room 591 may change as described above.
  • the front room 591 may have slid so that the size thereof is minimized.
  • the front room 591 is slid so that the internal volume thereof is maximized as illustrated in FIG. 33. Thereafter, the front room opening/closing part 59114 is opened as illustrated in FIG. 34. Then, the operator enters the internal space of the front room 591 through the front room opening/closing part 59114 and then closes the front room opening/closing part 59114. Subsequently, the operator opens the first entrance part 500 and moves to the outside. When the operator has moved to the outside, the front room 591 slides so that the volume thereof is minimized again.
  • a subject that slides the front room 591 may be another operator present in the pretreatment space 700 or an electric means (not shown), but is not limited thereto. In this case, at any moment that the operator exits the pretreatment space 700, the negative pressure in the pretreatment space 700 may be maintained.
  • the operator opens the first entrance part 500.
  • the front room opening/closing part 59114 is in a closed state.
  • the negative pressure in the pretreatment space 700 is maintained.
  • the front room 591 is slid so that the internal volume thereof is minimized as illustrated in FIG. 33.
  • the first entrance part 500 is closed.
  • the front room opening/closing part 59114 is opened, and the operator enters the pretreatment space 700.
  • the operator closes the front room opening/closing part 59114.
  • the front room 591 is slid so that the volume thereof is minimized. In this case, at any moment, the negative pressure in the pretreatment space 700 may be maintained.
  • the front room may be provided to the analysis space 800 and the second entrance part 600 for the analysis space 800.
  • the above-described front room 591 has been described as being provided in the pretreatment space 700 selected from the pretreatment space 700 and the outside, but the concept of the present disclosure is not limited thereto.
  • at least one front room 591 may be provided between a variety of spaces, for example, between the pretreatment space 700 and the analysis space 800, between the pretreatment space 700 and the first servant space 900, and between the analysis space 800 and the second servant space 1000.
  • an open area and an opening/closing part for opening and closing the open area may be provided in each of the spaces 700, 800, 900, and 1000.
  • each of the foregoing methods may be implemented as a computer program configured to perform the steps of the method and stored in a computer readable recording medium.
  • each of the methods may be implemented as a computer readable recording medium storing a computer program configured to perform the steps of the method.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Architecture (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Mechanical Engineering (AREA)
  • Biomedical Technology (AREA)
  • Transportation (AREA)
  • Pulmonology (AREA)
  • Civil Engineering (AREA)
  • Structural Engineering (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Combustion & Propulsion (AREA)
  • General Engineering & Computer Science (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

L'invention concerne une structure mobile pour le diagnostic. Un boîtier a un espace à l'intérieur de celui-ci pour recevoir un équipement de diagnostic, une zone ouverte de boîtier étant formée dans le boîtier. Une partie de chambre avant est reliée à des parties périphériques de la zone ouverte de boîtier pour sceller la zone ouverte de boîtier et fournit une chambre avant à dimension variable à une partie de l'espace du boîtier.
PCT/KR2022/006363 2021-05-03 2022-05-03 Structure mobile pour diagnostic WO2022235066A1 (fr)

Priority Applications (1)

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KR1020237040145A KR20230173183A (ko) 2021-05-03 2022-05-03 이동형 진단 구조물

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KR10-2021-0061105 2021-05-12
KR20210061105 2021-05-12

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040074212A1 (en) * 2002-10-22 2004-04-22 Sanki Engineering Co., Ltd. Patient isolation unit
US20080057854A1 (en) * 2006-08-15 2008-03-06 William David Muggah Patient isolation module and use thereof
US8733813B2 (en) * 2011-11-21 2014-05-27 Med 1 Partners, Llc Mobile treatment, diagnostic and minor surgery facility
KR20200089606A (ko) * 2017-03-16 2020-07-27 케어 스트레티직 디 아이 알 홀딩스 피티와이 리미티드 격리 텐트
KR102188117B1 (ko) * 2020-10-06 2020-12-08 (주)비에이에너지 안전관리 시스템형 음압 병상

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040074212A1 (en) * 2002-10-22 2004-04-22 Sanki Engineering Co., Ltd. Patient isolation unit
US20080057854A1 (en) * 2006-08-15 2008-03-06 William David Muggah Patient isolation module and use thereof
US8733813B2 (en) * 2011-11-21 2014-05-27 Med 1 Partners, Llc Mobile treatment, diagnostic and minor surgery facility
KR20200089606A (ko) * 2017-03-16 2020-07-27 케어 스트레티직 디 아이 알 홀딩스 피티와이 리미티드 격리 텐트
KR102188117B1 (ko) * 2020-10-06 2020-12-08 (주)비에이에너지 안전관리 시스템형 음압 병상

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