WO2022145766A1 - Membrane de capteur optique à structure microfine de détection d'oxygène dissous - Google Patents
Membrane de capteur optique à structure microfine de détection d'oxygène dissous Download PDFInfo
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- WO2022145766A1 WO2022145766A1 PCT/KR2021/018127 KR2021018127W WO2022145766A1 WO 2022145766 A1 WO2022145766 A1 WO 2022145766A1 KR 2021018127 W KR2021018127 W KR 2021018127W WO 2022145766 A1 WO2022145766 A1 WO 2022145766A1
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- dissolved oxygen
- optical sensor
- micro
- detecting dissolved
- microstructure
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- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 title claims abstract description 40
- 229910052760 oxygen Inorganic materials 0.000 title claims abstract description 40
- 239000001301 oxygen Substances 0.000 title claims abstract description 40
- 230000003287 optical effect Effects 0.000 title claims abstract description 33
- 239000012528 membrane Substances 0.000 title abstract 4
- 239000007850 fluorescent dye Substances 0.000 claims abstract description 17
- 238000001514 detection method Methods 0.000 claims abstract description 14
- 229910052714 tellurium Inorganic materials 0.000 claims abstract description 9
- PORWMNRCUJJQNO-UHFFFAOYSA-N tellurium atom Chemical compound [Te] PORWMNRCUJJQNO-UHFFFAOYSA-N 0.000 claims abstract description 9
- 239000007983 Tris buffer Substances 0.000 claims abstract description 7
- YAYGSLOSTXKUBW-UHFFFAOYSA-N ruthenium(2+) Chemical compound [Ru+2] YAYGSLOSTXKUBW-UHFFFAOYSA-N 0.000 claims abstract description 6
- DHDHJYNTEFLIHY-UHFFFAOYSA-N 4,7-diphenyl-1,10-phenanthroline Chemical compound C1=CC=CC=C1C1=CC=NC2=C1C=CC1=C(C=3C=CC=CC=3)C=CN=C21 DHDHJYNTEFLIHY-UHFFFAOYSA-N 0.000 claims abstract description 5
- KXXXUIKPSVVSAW-UHFFFAOYSA-K pyranine Chemical compound [Na+].[Na+].[Na+].C1=C2C(O)=CC(S([O-])(=O)=O)=C(C=C3)C2=C2C3=C(S([O-])(=O)=O)C=C(S([O-])(=O)=O)C2=C1 KXXXUIKPSVVSAW-UHFFFAOYSA-K 0.000 claims description 10
- 238000000034 method Methods 0.000 claims description 9
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 claims description 8
- 229910052711 selenium Inorganic materials 0.000 claims description 8
- 239000011669 selenium Substances 0.000 claims description 8
- 239000006087 Silane Coupling Agent Substances 0.000 claims description 4
- NKSJNEHGWDZZQF-UHFFFAOYSA-N ethenyl(trimethoxy)silane Chemical compound CO[Si](OC)(OC)C=C NKSJNEHGWDZZQF-UHFFFAOYSA-N 0.000 claims description 4
- ZNOCGWVLWPVKAO-UHFFFAOYSA-N trimethoxy(phenyl)silane Chemical compound CO[Si](OC)(OC)C1=CC=CC=C1 ZNOCGWVLWPVKAO-UHFFFAOYSA-N 0.000 claims description 4
- BPSIOYPQMFLKFR-UHFFFAOYSA-N trimethoxy-[3-(oxiran-2-ylmethoxy)propyl]silane Chemical compound CO[Si](OC)(OC)CCCOCC1CO1 BPSIOYPQMFLKFR-UHFFFAOYSA-N 0.000 claims description 4
- SJECZPVISLOESU-UHFFFAOYSA-N 3-trimethoxysilylpropan-1-amine Chemical compound CO[Si](OC)(OC)CCCN SJECZPVISLOESU-UHFFFAOYSA-N 0.000 claims description 2
- UUEWCQRISZBELL-UHFFFAOYSA-N 3-trimethoxysilylpropane-1-thiol Chemical compound CO[Si](OC)(OC)CCCS UUEWCQRISZBELL-UHFFFAOYSA-N 0.000 claims description 2
- XDLMVUHYZWKMMD-UHFFFAOYSA-N 3-trimethoxysilylpropyl 2-methylprop-2-enoate Chemical compound CO[Si](OC)(OC)CCCOC(=O)C(C)=C XDLMVUHYZWKMMD-UHFFFAOYSA-N 0.000 claims description 2
- BLRPTPMANUNPDV-UHFFFAOYSA-N Silane Chemical compound [SiH4] BLRPTPMANUNPDV-UHFFFAOYSA-N 0.000 claims description 2
- BOTDANWDWHJENH-UHFFFAOYSA-N Tetraethyl orthosilicate Chemical compound CCO[Si](OCC)(OCC)OCC BOTDANWDWHJENH-UHFFFAOYSA-N 0.000 claims description 2
- KQAHMVLQCSALSX-UHFFFAOYSA-N decyl(trimethoxy)silane Chemical compound CCCCCCCCCC[Si](OC)(OC)OC KQAHMVLQCSALSX-UHFFFAOYSA-N 0.000 claims description 2
- ZZNQQQWFKKTOSD-UHFFFAOYSA-N diethoxy(diphenyl)silane Chemical compound C=1C=CC=CC=1[Si](OCC)(OCC)C1=CC=CC=C1 ZZNQQQWFKKTOSD-UHFFFAOYSA-N 0.000 claims description 2
- JJQZDUKDJDQPMQ-UHFFFAOYSA-N dimethoxy(dimethyl)silane Chemical compound CO[Si](C)(C)OC JJQZDUKDJDQPMQ-UHFFFAOYSA-N 0.000 claims description 2
- AHUXYBVKTIBBJW-UHFFFAOYSA-N dimethoxy(diphenyl)silane Chemical compound C=1C=CC=CC=1[Si](OC)(OC)C1=CC=CC=C1 AHUXYBVKTIBBJW-UHFFFAOYSA-N 0.000 claims description 2
- YYLGKUPAFFKGRQ-UHFFFAOYSA-N dimethyldiethoxysilane Chemical compound CCO[Si](C)(C)OCC YYLGKUPAFFKGRQ-UHFFFAOYSA-N 0.000 claims description 2
- FWDBOZPQNFPOLF-UHFFFAOYSA-N ethenyl(triethoxy)silane Chemical compound CCO[Si](OCC)(OCC)C=C FWDBOZPQNFPOLF-UHFFFAOYSA-N 0.000 claims description 2
- BFXIKLCIZHOAAZ-UHFFFAOYSA-N methyltrimethoxysilane Chemical compound CO[Si](C)(OC)OC BFXIKLCIZHOAAZ-UHFFFAOYSA-N 0.000 claims description 2
- 229910000077 silane Inorganic materials 0.000 claims description 2
- LFQCEHFDDXELDD-UHFFFAOYSA-N tetramethyl orthosilicate Chemical compound CO[Si](OC)(OC)OC LFQCEHFDDXELDD-UHFFFAOYSA-N 0.000 claims description 2
- CPUDPFPXCZDNGI-UHFFFAOYSA-N triethoxy(methyl)silane Chemical compound CCO[Si](C)(OCC)OCC CPUDPFPXCZDNGI-UHFFFAOYSA-N 0.000 claims description 2
- JCVQKRGIASEUKR-UHFFFAOYSA-N triethoxy(phenyl)silane Chemical compound CCO[Si](OCC)(OCC)C1=CC=CC=C1 JCVQKRGIASEUKR-UHFFFAOYSA-N 0.000 claims description 2
- -1 tris (4,7-diphenyl-1,10-phenanthroline) ruthenium (II) Chemical compound 0.000 claims description 2
- 229920001002 functional polymer Polymers 0.000 abstract description 5
- 230000002265 prevention Effects 0.000 abstract description 3
- AQCDIIAORKRFCD-UHFFFAOYSA-N cadmium selenide Chemical compound [Cd]=[Se] AQCDIIAORKRFCD-UHFFFAOYSA-N 0.000 abstract 1
- 238000011109 contamination Methods 0.000 abstract 1
- 239000010408 film Substances 0.000 description 23
- 239000007787 solid Substances 0.000 description 11
- 239000007788 liquid Substances 0.000 description 9
- 240000007472 Leucaena leucocephala Species 0.000 description 7
- 235000010643 Leucaena leucocephala Nutrition 0.000 description 7
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 4
- 238000013461 design Methods 0.000 description 4
- 230000008901 benefit Effects 0.000 description 3
- 230000008859 change Effects 0.000 description 3
- 238000006243 chemical reaction Methods 0.000 description 3
- 238000011161 development Methods 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000005284 excitation Effects 0.000 description 2
- 239000007789 gas Substances 0.000 description 2
- 229910052739 hydrogen Inorganic materials 0.000 description 2
- 239000001257 hydrogen Substances 0.000 description 2
- 230000005661 hydrophobic surface Effects 0.000 description 2
- 229910052742 iron Inorganic materials 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012544 monitoring process Methods 0.000 description 2
- 239000000523 sample Substances 0.000 description 2
- 229910052710 silicon Inorganic materials 0.000 description 2
- 239000010703 silicon Substances 0.000 description 2
- BIJNHUAPTJVVNQ-UHFFFAOYSA-N 1-Hydroxypyrene Chemical compound C1=C2C(O)=CC=C(C=C3)C2=C2C3=CC=CC2=C1 BIJNHUAPTJVVNQ-UHFFFAOYSA-N 0.000 description 1
- POEOLRMDMUNLPY-UHFFFAOYSA-N 2,3-diphenyl-1,10-phenanthroline Chemical compound C1=CC=CC=C1C1=CC2=CC=C(C=CC=N3)C3=C2N=C1C1=CC=CC=C1 POEOLRMDMUNLPY-UHFFFAOYSA-N 0.000 description 1
- DWPHNSNJHSXKPT-UHFFFAOYSA-N 4,7-diphenyl-1,10-phenanthroline;ruthenium(2+) Chemical compound [Ru+2].C1=CC=CC=C1C1=CC=NC2=C1C=CC1=C(C=3C=CC=CC=3)C=CN=C21 DWPHNSNJHSXKPT-UHFFFAOYSA-N 0.000 description 1
- BZTDTCNHAFUJOG-UHFFFAOYSA-N 6-carboxyfluorescein Chemical compound C12=CC=C(O)C=C2OC2=CC(O)=CC=C2C11OC(=O)C2=CC=C(C(=O)O)C=C21 BZTDTCNHAFUJOG-UHFFFAOYSA-N 0.000 description 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 1
- 240000002853 Nelumbo nucifera Species 0.000 description 1
- 235000006508 Nelumbo nucifera Nutrition 0.000 description 1
- 235000006510 Nelumbo pentapetala Nutrition 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000003666 anti-fingerprint Effects 0.000 description 1
- 230000003373 anti-fouling effect Effects 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 238000005102 attenuated total reflection Methods 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 229910002092 carbon dioxide Inorganic materials 0.000 description 1
- 239000001569 carbon dioxide Substances 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000000975 dye Substances 0.000 description 1
- 230000005672 electromagnetic field Effects 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 230000003100 immobilizing effect Effects 0.000 description 1
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- 239000007793 ph indicator Substances 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
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- 230000000171 quenching effect Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
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- 230000000630 rising effect Effects 0.000 description 1
- 239000011540 sensing material Substances 0.000 description 1
- 238000004611 spectroscopical analysis Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000010409 thin film Substances 0.000 description 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
- HRXKRNGNAMMEHJ-UHFFFAOYSA-K trisodium citrate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O HRXKRNGNAMMEHJ-UHFFFAOYSA-K 0.000 description 1
Images
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/18—Water
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6402—Atomic fluorescence; Laser induced fluorescence
- G01N21/6404—Atomic fluorescence
- G01N2021/6406—Atomic fluorescence multi-element
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
- G01N2021/6434—Optrodes
Definitions
- the present invention relates to an optical sensor film for detecting dissolved oxygen having a micro-microstructure, and more particularly, a micro-pattern for anti-fouling and fingerprint prevention and fluorescence gain efficiency improvement of a fluorescent sensor according to the expansion of the use of a touch screen in a smart device display. It relates to an optical sensor film for detecting dissolved oxygen having a microstructure, which is a functional polymer film based on a structure.
- Dissolved oxygen, temperature and pH are important parameters in environmental monitoring, marine research, food industry, biotechnology and medicine.
- Optical detection has advantages over other methods because it is possible to measure non-invasively through the glass window of a bioreactor or reaction vessel.
- the sensing material is placed on the inner wall of the reaction vessel, and detection by reflection or fluorescence is performed outside the reaction vessel.
- the optical sensor has an advantage in that an electromagnetic field is not generated because it measures a signal using light instead of an existing electronic device and transmits measurement information through light.
- optical dyes that selectively emit light according to specific substances (dissolved oxygen molecules, carbon dioxide molecules, etc.) or changes in pH, their use in various sensor fields is being highlighted.
- the small multi-bioreactor has the advantage of minimizing the process development cost by enabling the development of process conditions to be achieved in a short time and at low cost in the optimization of pharmaceutical and biological product production processes.
- Rudpp tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) complex
- HPTS 8-hydroxypyrene
- CdSeTe cadimium selenium tellurium
- HPTS has a characteristic of emitting fluorescence of 520 nm when excitation light of 410 nm is incident, and the fluorescence intensity tends to increase as the concentration of hydrogen ions decreases.
- CdSeTe cadimium selenium tellurium
- CdSeTe cadimium selenium tellurium
- the present invention was devised to improve the above problems, and has a micro microstructure, which is a functional polymer film based on a micro pattern structure, so that the stain resistance and fingerprint prevention and fluorescent sensor according to the expansion of the use of touch screens in smart device displays. It aims to improve the fluorescence gain efficiency.
- an optical sensor film for detecting dissolved oxygen having a microstructure includes a sensor layer for temperature detection in which CdSeTe (cadimium selenium tellurium) fluorescent dye is fixed on a support, and tris (4,7-) and forming a sensor layer for detecting dissolved oxygen to which a diphenyl-1,10-phenanthroline)ruthenium(II) complex (Rudpp) fluorescent dye is immobilized.
- CdSeTe cadimium selenium tellurium
- Rudpp diphenyl-1,10-phenanthroline
- the optical sensor film for detecting dissolved oxygen having the microstructure includes a) preparing a sensor layer for temperature detection in which CdSeTe (cadimium selenium tellurium) fluorescent dye is fixed on a support, and b) Tris on the sensor layer for temperature detection (4,7-diphenyl-1,10-phenanthroline) ruthenium (II) complex (Rudpp) characterized in that it comprises the step of preparing a sensor layer for detecting dissolved oxygen immobilized with a fluorescent dye.
- CdSeTe cadimium selenium tellurium
- Fluorescent dyes are 3-glycidoxypropyltrimethoxysilane, 3-aminopropyltrimethoxysilane, phenyltrimethoxysilane, vinyltrimethoxysilane, and 3-(trimethoxysilyl)propyl methacrylate. It is characterized in that it is immobilized using at least one silane coupling agent selected from the group consisting of.
- the tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) complex (Rudpp) fluorescent dye in step b) is methyltrimethoxysilane, tetramethoxysilane, dimethyldimethoxysilane, tetra Ethoxysilane, methyltriethoxysilane, dimethyldiethoxysilane, phenyltrimethoxysilane, diphenyldimethoxysilane, phenyltriethoxysilane, diphenyldiethoxysilane, decyltrimethoxysilane, isobutyltrimethoxy It is characterized by immobilization using at least one silane coupling agent selected from the group consisting of silane, vinyltrimethoxysilane, vinyltriethoxysilane, glycidooxypropyltrimethoxysilane, and mercaptopropyltrimethoxysilane. .
- the optical sensor film for detecting dissolved oxygen having a micro microstructure according to the present invention has a micro microstructure, which is a functional polymer film based on a micro pattern structure. has the effect of improving the fluorescence gain efficiency of
- FIG. 1 shows the configuration of an optical sensor film for detecting dissolved oxygen having a microstructure according to an embodiment of the present invention
- FIG. 2 is a liquid drop model in the micro pattern structure of the optical sensor film for detecting dissolved oxygen having a micro microstructure according to an embodiment of the present invention
- FIG. 3 is a design shape structure of an optical sensor film for detecting dissolved oxygen having a microstructure according to an embodiment of the present invention
- FIG. 4 is a process diagram showing a photomask manufacturing process of an optical sensor film for detecting dissolved oxygen having a microstructure according to an embodiment of the present invention
- FIG. 5 is a photomask drawing and a manufactured photomask image for realizing a designed hydrogen surface of an optical sensor film for detecting dissolved oxygen having a microstructure according to an embodiment of the present invention
- FIG. 6 is a silicon stamp manufacturing process diagram for imprint for realization of the hydrophobic surface of the optical sensor film for detecting dissolved oxygen having a microstructure according to an embodiment of the present invention is shown,
- FIG. 7 is a micro-patterned silicon stamp image for the fabricated hydrophobic surface structure of the optical sensor film for detecting dissolved oxygen having a micro-structure according to an embodiment of the present invention.
- first, second, etc. may be used to describe various elements, but the elements should not be limited by the terms. The above terms are used only for the purpose of distinguishing one component from another. For example, without departing from the scope of the present invention, a first component may be referred to as a second component, and similarly, a second component may also be referred to as a first component.
- FIG. 1 to 7 show an optical sensor film 10 for detecting dissolved oxygen having a microstructure according to an embodiment of the present invention.
- the optical sensor film 10 for detecting dissolved oxygen having a microstructure includes a support 300 , a sensor layer 200 for detecting temperature, and a sensor layer 100 for detecting dissolved oxygen.
- the contact angle of the liquid droplet on the flat solid surface of the support 300 is determined by Young's equation.
- Equation 1 denotes the interfacial energy between solid-gas, solid-liquid, and liquid-gas, respectively.
- the contact angle no longer follows Young's equation, and the contact angle is determined by two models proposed by Wenzel and Cassie.
- r is the area where the droplet actually touches the solid surface ( ) and the area projected from the top ( ), and is defined as the roughness ratio.
- FIG. 3 the design shape structure of the micro-pattern of the support is shown.
- Equation 4 is calculated by Equation 4 in the square protrusion and depression shapes having shape parameters.
- wenzel's model states that when the contact angle of a liquid droplet is less than 90° on a flat solid surface ( ), the contact angle on an uneven solid surface Is If the contact angle of the liquid droplet is greater than 90° on a flat solid surface ( ), Is will get bigger
- the contact angle at this time is calculated by Equation 5 above, is the area the liquid droplet actually touches the solid surface ( , the projected area) and the projected area from the top ( ), and is defined as a solid fraction.
- the micro-pattern shape is designed based on a pattern of protrusion and depression of a square having micro-sized protrusions similar to the surface shape of a lotus leaf.
- Table 1 shows the theoretical contact angle change values according to the micro-pattern pillar structure
- Table 2 shows the theoretical contact angle change values according to the micro-pattern pore structure.
- the design dimensions are summarized as in Tables 1 and 2 above, and the pitch was changed while the width a and the height h of the exit structure were fixed to 10 ⁇ m, respectively.
- Table 1 represents the roughness ratio and the dent ratio defined as the ratio of the floor area to the total area projected from the top, respectively.
- the spacing between structures approaches or becomes larger than the diameter of the water droplet measured when the contact angle is measured, and the actual contact angle shows a different aspect from the theoretical contact angle.
- the concave shape of the square is the reverse of the protrusion of the square, and has a major difference from the protrusion.
- a network-type channel is formed between the square microstructures, so that the water droplets are easy to spread or move.
- the recessed microstructure follows Cassie's model even when the surface is hydrophilic because it is relatively difficult to move water droplets due to the rising network-type barrier ribs, and thus exhibits greater hydrophobicity.
- the optical sensor film for detecting dissolved oxygen having a micro microstructure of the present invention described above has a micro microstructure, which is a functional polymer film based on a micro pattern structure. There is an effect of improving the fluorescence gain efficiency of the fluorescent sensor.
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- Physics & Mathematics (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Optics & Photonics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Abstract
La présente invention concerne une membrane de capteur optique à structure microfine de détection d'oxygène dissous et plus particulièrement un film polymère fonctionnel à base de structure à micromotifs permettant d'améliorer la résistance à la contamination, la prévention d'empreintes digitales et l'efficacité de gain de fluorescence d'un capteur fluorescent, grâce à l'agrandissement de l'utilisation d'un écran tactile d'un affichage de dispositif intelligent. Selon la présente invention, la membrane de capteur optique à structure microfine de détection d'oxygène dissous comprend : une étape de formation, sur un support, d'une couche de capteur thermosensible à laquelle est fixé un colorant fluorescent de cadmium, de sélénium et de tellure (Cd, Se, Te) ; et une couche détectrice d'oxygène dissous, à laquelle est fixé un colorant fluorescent complexe de tris(4,7-diphényl-1,10-phénanthroline)ruthénium (II) (Ru-dpp).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020200186272A KR20220094741A (ko) | 2020-12-29 | 2020-12-29 | 마이크로 미세구조를 가지는 용존산소 검출용 광학식 센서막 |
| KR10-2020-0186272 | 2020-12-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| WO2022145766A1 true WO2022145766A1 (fr) | 2022-07-07 |
Family
ID=82260504
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/KR2021/018127 WO2022145766A1 (fr) | 2020-12-29 | 2021-12-02 | Membrane de capteur optique à structure microfine de détection d'oxygène dissous |
Country Status (2)
| Country | Link |
|---|---|
| KR (1) | KR20220094741A (fr) |
| WO (1) | WO2022145766A1 (fr) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116574399A (zh) * | 2023-06-14 | 2023-08-11 | 广东隆宇传感科技有限公司 | 一种荧光帽用改性硅溶胶及其制备和应用方法、氧敏感荧光帽 |
| CN117030667A (zh) * | 2023-07-14 | 2023-11-10 | 北京邮电大学 | 多功能的光学传感器及其制备方法 |
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| KR100940513B1 (ko) * | 2008-04-30 | 2010-02-10 | 전남대학교산학협력단 | 용존산소, ｐＨ 및 온도의 2종 이상의 변수의 동시 검출용광학 센서막, 장치 및 방법 |
| KR101002716B1 (ko) * | 2008-12-05 | 2010-12-21 | 전남대학교산학협력단 | 용존산소, ｐＨ 및 온도의 2종 이상의 변수의 동시 검출용 다중층 광학 센서막 제조방법 및 장치 |
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| KR101493645B1 (ko) | 2013-03-07 | 2015-02-13 | 이영환 | 센서막이 보호된 광학적 용존산소 측정센서 |
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| US20020025547A1 (en) * | 2000-08-14 | 2002-02-28 | Govind Rao | Bioreactor and bioprocessing technique |
| KR100860958B1 (ko) * | 2007-08-08 | 2008-09-30 | 전남대학교산학협력단 | 광학센서막 부착형 다채널 소형 생물반응기 |
| KR100940513B1 (ko) * | 2008-04-30 | 2010-02-10 | 전남대학교산학협력단 | 용존산소, ｐＨ 및 온도의 2종 이상의 변수의 동시 검출용광학 센서막, 장치 및 방법 |
| KR101002716B1 (ko) * | 2008-12-05 | 2010-12-21 | 전남대학교산학협력단 | 용존산소, ｐＨ 및 온도의 2종 이상의 변수의 동시 검출용 다중층 광학 센서막 제조방법 및 장치 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116574399A (zh) * | 2023-06-14 | 2023-08-11 | 广东隆宇传感科技有限公司 | 一种荧光帽用改性硅溶胶及其制备和应用方法、氧敏感荧光帽 |
| CN116574399B (zh) * | 2023-06-14 | 2023-12-19 | 广东隆宇传感科技有限公司 | 一种荧光帽用改性硅溶胶及其制备和应用方法、氧敏感荧光帽 |
| CN117030667A (zh) * | 2023-07-14 | 2023-11-10 | 北京邮电大学 | 多功能的光学传感器及其制备方法 |
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| KR20220094741A (ko) | 2022-07-06 |
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