WO2022142458A1 - 动物扫描方法、装置和系统 - Google Patents

动物扫描方法、装置和系统 Download PDF

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Publication number
WO2022142458A1
WO2022142458A1 PCT/CN2021/117615 CN2021117615W WO2022142458A1 WO 2022142458 A1 WO2022142458 A1 WO 2022142458A1 CN 2021117615 W CN2021117615 W CN 2021117615W WO 2022142458 A1 WO2022142458 A1 WO 2022142458A1
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WIPO (PCT)
Prior art keywords
animal
scanned
scanning
cabin
type
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Application number
PCT/CN2021/117615
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English (en)
French (fr)
Inventor
昌赢
彭程远
陈力
柯海良
Original Assignee
武汉联影生命科学仪器有限公司
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Priority claimed from CN202011636941.6A external-priority patent/CN114694822A/zh
Priority claimed from CN202011636936.5A external-priority patent/CN114680873A/zh
Priority claimed from CN202011633122.6A external-priority patent/CN114697538B/zh
Application filed by 武汉联影生命科学仪器有限公司 filed Critical 武汉联影生命科学仪器有限公司
Priority to EP21913205.7A priority Critical patent/EP4272624A1/en
Publication of WO2022142458A1 publication Critical patent/WO2022142458A1/zh
Priority to US18/217,134 priority patent/US20230337638A1/en

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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K29/00—Other apparatus for animal husbandry
    • A01K29/005—Monitoring or measuring activity, e.g. detecting heat or mating
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K29/00—Other apparatus for animal husbandry
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0077—Devices for viewing the surface of the body, e.g. camera, magnifying lens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/103—Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A61B5/107—Measuring physical dimensions, e.g. size of the entire body or parts thereof
    • A61B5/1072—Measuring physical dimensions, e.g. size of the entire body or parts thereof measuring distances on the body, e.g. measuring length, height or thickness
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/103—Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A61B5/11—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb
    • A61B5/1104—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb induced by stimuli or drugs
    • A61B5/1105—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb induced by stimuli or drugs of laboratory animals, e.g. activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/44—Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
    • A61B5/448—Hair evaluation, e.g. for hair disorder diagnosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6887—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient mounted on external non-worn devices, e.g. non-medical devices
    • A61B5/6888—Cabins
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K11/00—Marking of animals
    • A01K11/006—Automatic identification systems for animals, e.g. electronic devices, transponders for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2503/00—Evaluating a particular growth phase or type of persons or animals
    • A61B2503/40—Animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2503/00—Evaluating a particular growth phase or type of persons or animals
    • A61B2503/42—Evaluating a particular growth phase or type of persons or animals for laboratory research
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0033—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room
    • A61B5/0037—Performing a preliminary scan, e.g. a prescan for identifying a region of interest
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
    • A61B5/0816—Measuring devices for examining respiratory frequency
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/318—Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • A61B5/325—Preparing electrode sites, e.g. by abrasion

Definitions

  • the present application relates to the technical field of medical imaging, and more particularly, to an animal scanning method, device and system.
  • the corresponding scanning protocol Before performing preclinical image scanning on animals, the corresponding scanning protocol needs to be set first. After the scanning protocol is determined, the animal is set up according to the optimal scanning body position corresponding to the scanning protocol, and then the scanning is performed. When setting up the animal, in order to avoid the animal moving, the animal is usually anesthetized, and then the animal's body is fixed.
  • Some embodiments of the present application provide an animal scanning method, the method comprising:
  • the type of the animal to be scanned matches the type of the animal cabin, matching and presenting a corresponding scanning protocol according to the type of the animal to be scanned;
  • the method further includes:
  • the type of the animal to be scanned is acquired according to the image of the animal to be scanned, and/or the animal to be scanned is monitored in real time according to the image of the animal to be scanned.
  • the method before the scanning according to the user-defined scanning protocol, the method further includes: judging whether the user-defined scanning protocol matches the type of the animal to be scanned, and if not, Then, it prompts to modify the user-defined scanning protocol.
  • the method further includes:
  • the acquiring the type of the animal to be scanned includes:
  • the acquiring the type of the animal to be scanned includes:
  • the obtained body length parameters and body weight parameters of the animal are compared with the pre-stored standard body length and standard body weight respectively to determine the type information of the animal.
  • the method further includes:
  • the animal's hair parameters are also obtained, and the animal type information is determined according to the animal's hair parameters, body length parameters and weight parameters; the hair parameters include at least one of the length of the hair, the diameter of the hair, and the color of the hair .
  • the obtaining the body length parameter of the animal by identifying the image includes:
  • Set scales with scales on both sides of the animal identify the scales on the scale to obtain body length parameters and/or mark feature points on the animal's body, and determine the animal's body length parameters by identifying the feature points.
  • the acquiring the body weight parameter of the animal to be scanned includes:
  • the body weight parameters of the animal to be scanned are obtained.
  • the method further includes:
  • identifying the type of the animal cabin where the animal to be scanned is located, and judging whether the type of the animal to be scanned matches the type of the animal cabin includes:
  • the type of the animal cabin includes the corresponding animal bed type and the number of animal beds;
  • the method before performing scanning according to a corresponding scanning protocol, or scanning according to a user-defined scanning protocol, the method further includes:
  • the scanning body position includes scanning feature points corresponding to a plurality of the actual feature points one-to-one;
  • the body position adjustment parameters are output to guide the body position adjustment, and scanning is performed until the similarity between the actual body position and the scanned body position is greater than the set threshold.
  • the method before acquiring the image of the animal to be scanned, the method further includes:
  • the distance between the animal cabin and the camera is acquired, and the focal length of the camera is adjusted according to the distance, so as to realize the focusing of the camera.
  • the obtaining the distance between the animal cabin and the camera includes:
  • the real-time distance between the animal cabin and the camera is calculated according to the initial distance and the real-time travel.
  • an animal scanning device including:
  • a first acquisition unit used to acquire the type of the animal to be scanned
  • a judgment unit for identifying the type of the animal cabin where the animal to be scanned is located, and judging whether the type of the animal to be scanned matches the type of the animal cabin;
  • a matching unit configured to match and present a corresponding scanning protocol according to the type of the animal to be scanned if the type of the animal to be scanned matches the type of the animal cabin;
  • the scanning unit is used for scanning according to a corresponding scanning protocol, or scanning according to a user-defined scanning protocol.
  • Some embodiments of the present application provide an animal scanning system, including the animal scanning device according to the second aspect, and further including an animal cabin, an image acquisition device, and a physiological signal detection device;
  • the animal cabin is arranged on the bed and is used to place the animals to be scanned;
  • the image acquisition device is used to acquire the image of the animal to be scanned
  • the physiological signal detection device is used to obtain the physiological signal of the animal to be scanned
  • the animal scanning device is used for scanning the animal to be scanned.
  • it also includes a light source and an animal imaging device body, wherein,
  • the animal imaging device body has a scanning hole, the animal cabin can move along the axial direction of the scanning hole, and the light source is fixedly installed on the animal imaging device body.
  • the image acquisition device is provided on the animal cabin and/or on the body of the animal imaging device.
  • FIG. 1 is a schematic flowchart of an animal scanning method provided according to some embodiments of the present application.
  • FIG. 2 is a schematic flowchart of an animal scanning method provided according to some embodiments of the present application.
  • FIG. 3 is a schematic flowchart of an animal scanning method provided according to some embodiments of the present application.
  • FIG. 4 is a schematic flowchart of an animal scanning method provided according to some embodiments of the present application.
  • FIG. 5 is a schematic flowchart of an animal scanning method provided according to some embodiments of the present application.
  • FIG. 6 is a diagram of an animal cabin registration information input interface diagram of an animal scanning method provided according to some embodiments of the present application.
  • FIG. 7 is a schematic flowchart of an animal scanning method provided according to some embodiments of the present application.
  • FIG. 8 is a schematic diagram of similarity calculation of an animal scanning method provided according to some embodiments of the present application.
  • FIG. 9 is a schematic structural diagram of a video surveillance system of an animal imaging device provided according to some embodiments of the present application.
  • FIG. 10 is a schematic diagram of a physical model of imaging by a camera lens provided according to some embodiments of the present application.
  • FIG. 11 is a structural block diagram of an animal scanning device provided according to some embodiments of the present application.
  • FIG. 12 is an architectural diagram of an animal scanning system provided according to some embodiments of the present application.
  • 1 camera; 2: animal cabin; 3: light source; 4: animal imaging device body; 5: animal scanning device;
  • FIG. 1 is a flowchart of an animal scanning method disclosed according to some embodiments of the present application, the method includes steps:
  • the scanning device may acquire an image of the animal to be scanned, and acquire the type of the animal to be scanned according to the image of the animal to be scanned.
  • the scanning device may capture images of the animals to be scanned through a camera, for example, the camera may be a video camera or a high-definition camera.
  • S102 Identify the type of the animal cabin where the animal to be scanned is located, and determine whether the type of the animal to be scanned matches the type of the animal cabin.
  • data such as a scanned image of an animal to be scanned are transmitted to a scanning terminal outside the animal cabin during scanning, and a data transmission interface is provided on the animal cabin, and the animal can be identified by the type of the data transmission interface and the type of data transmitted Type of cabin.
  • the matching judgment between the animal cabin and the animal can be completed. If the animal cabin does not match the animal, the user is prompted to replace the animal; if the animal cabin matches the animal, the animal cabin can be matched according to the animal The type matches the corresponding scan protocol.
  • the selection of the scanning protocol can be implemented in two ways: automatic matching or user-defined.
  • the automatic matching of scanning protocols can be achieved by establishing a scanning protocol library, establishing a corresponding scanning protocol for each scanning area of each animal, and automatically matching in the scanning protocol library according to the type of animal to be scanned and the scanning area. That's it. If the user feels that the scanning protocol obtained by automatic matching is wrong or the matching degree is not high, or if the experienced operator thinks that the scanning protocol of automatic matching needs to be modified, the user can customize the scanning protocol.
  • S104 scan according to a corresponding scanning protocol, or scan according to a user-defined scanning protocol.
  • the scanning device may scan according to a scanning protocol matching the type of the animal to be scanned, or may scan according to a user-defined scanning protocol.
  • animal species identification is performed before animal scanning, so as to perform automatic matching of scanning protocols according to animal species.
  • scanning protocol matching there is no need to manually input basic information of animals, and scanning protocol matching Then, it is presented to the user. If the user is not satisfied with the matching scanning protocol, the scanning protocol can be customized, thereby making the selection of the scanning protocol more flexible.
  • the matching situation of the animal and the animal cabin is automatically judged, and the subsequent scanning protocol is determined and the scanning process is carried out on the premise of ensuring the matching between the animal and the animal cabin, which further improves the automation of the scanning process.
  • an image of the animal to be scanned is acquired, the type of the animal to be scanned is acquired according to the image of the animal to be scanned, and/or, the image to be scanned is to be scanned according to the image of the animal to be scanned Animals are monitored in real time.
  • the scanning device can also monitor the animal to be scanned in real time.
  • the animal scanning method includes:
  • the scanning device acquires images of the animal to be scanned. In some embodiments, the scanning device can acquire the image of the animal to be scanned through its own camera, and can also acquire the image of the animal to be scanned collected from the camera through a communication connection with the camera.
  • S202 Acquire the type of the animal to be scanned according to the image of the animal to be scanned, and/or monitor the animal to be scanned in real time.
  • the scanning device may obtain the body length parameter of the animal to be scanned according to the image of the animal to be scanned, and obtain the body length parameter of the animal to be scanned according to the body length parameter of the animal to be scanned. Scan the species of animals.
  • the image of the animal to be scanned here is a static image of the animal to be scanned. The static image may be captured by an optical camera with a camera before scanning, or may be acquired by a high-definition camera with a camera.
  • the scanning device may monitor the animal to be scanned in real time according to the image of the animal to be scanned.
  • the image of the animal to be scanned here is a real-time image of the animal to be scanned.
  • the real-time image can be acquired in real-time during the scanning process by a high-definition camera with a camera.
  • the type of the animal to be scanned can be quickly acquired according to the image of the animal to be scanned, and real-time video monitoring of the animal to be scanned can be performed according to the image of the animal to be scanned during the animal imaging experiment, so that the staff can obtain real-time access to the animal cabin. of animals.
  • the above-mentioned method further includes: It is judged whether the user-defined scanning protocol matches the type of the animal to be scanned. If it does not match, the user-defined scanning protocol is prompted to be modified.
  • the scanning protocol and its corresponding optimal scanning body position output value can be displayed on the scanning terminal, so that the user can view it and at the same time guide the animal's position.
  • the scanning terminal displays the scanning protocol and the corresponding optimal scanning body position
  • the user can manually check the matching scanning protocol and scanning body position on the scanning terminal. Select the automatically recommended scanning protocol and the best scanning body position, but manually set the scanning protocol and scanning body position, or modify the matching scanning protocol and scanning body position. It is preferable to display the scanned body position in the form of a body model diagram. The body model diagram of the animal is displayed on the scanning terminal.
  • mice support whole-body scans, brain scans, etc.
  • dogs support single/multi-bed, chest, brain scans, etc.
  • the scanning device can prompt the scanning device to respond to the user's self-definition if the user-defined scanning protocol does not match the type of the animal to be scanned.
  • the defined scan protocol is modified to ensure the accuracy of the scan protocol for the animals to be scanned.
  • the animal scanning method includes:
  • the physiological signal of the animal to be scanned and the real-time image of the animal can be combined. Judging the survival status of animals, to avoid the death of some animals due to intolerance to anesthetics or other reasons, and users do not find out in time, resulting in invalid scanning.
  • the physiological signal does not exist and the animal to be scanned is not identified in the real-time image of the animal, it is determined that the animal is not placed in the scanning area; if the physiological signal exists, and the animal to be scanned can be identified in the real-time image of the animal Scan the animal, it is judged that the animal has been placed in the scanning area and is alive; if the physiological signal does not exist, but the animal to be scanned can be identified in the real-time image of the animal, it is judged that the animal is dead. With the animal to be scanned alive, the scanning process can continue.
  • a physiological signal or a real-time image can be used alone to determine whether the animal to be scanned is alive, or a physiological signal can be obtained through the real-time image (for example, according to the real-time image). Obtain breathing signal) to judge whether the animal to be scanned is alive.
  • the scanning device determines that the animal to be scanned is dead in combination with the physiological signals and real-time images of the animal to be scanned, it outputs an animal sample replacement reminder to promptly replace the dead animal sample.
  • the scanning device can combine the physiological signals and real-time images of the animals to be scanned to determine whether the animals to be scanned are alive, so as to avoid some animals due to intolerance to anesthetics or other diseases. The cause of death occurs, and the user does not find it in time, and an invalid scan occurs.
  • the type of the animal to be scanned may be acquired directly by performing image recognition on the acquired image.
  • the type of the animal to be scanned can also be obtained through the physiological signal of the animal to be scanned, and the type of the animal to be scanned can also be obtained according to the body length parameter and weight parameter of the animal to be scanned.
  • the above S101 includes:
  • the animal species is identified by physiological signals.
  • the physiological signal database includes three animals: mice, rats, and rabbits.
  • the physiological signal range of mice is set to: body temperature 37-39 °C, heart rate 470-780 beats/min, body weight 15- 25 grams;
  • the physiological signal range of the rat is set as: body temperature 37.8-38.8 °C, heart rate 260-450 beats/min, body weight of 180-500 grams;
  • the physiological signal range of the rabbit is set as: body temperature 38.5-39.5 °C, heart rate 180- 250 times/min, weight 500-2000 grams.
  • the physiological signals of the animal to be scanned are acquired, and the physiological signals of the animal to be scanned are matched in the physiological signal database to match the animal species whose physiological signals of the animal to be scanned are all within the corresponding physiological signal range, Get the type of animal to be scanned. If there are more than one animal species matching the animal to be scanned (all physiological signals are in the corresponding physiological signal range), the animal species with the highest matching degree is selected as the final animal species to be scanned.
  • the matching degree can be calculated by the following formula: Among them, P j is the matching degree between the animal to be scanned and the j-th animal species, xi is the value of the physiological signal of the animal to be scanned i-th, The mean value of the physiological signal of the ith physiological signal of the jth animal species, The average value of the upper limit value and the lower limit value of the corresponding physiological signal range can be taken.
  • the animal species matching the animal to be scanned is zero, the animal species with the largest number of items matching the physiological signals of the animal to be scanned is selected as the final species of the animal to be scanned. If there are multiple animal species with the largest number of matching physiological signals, select the animal species with the highest matching degree as the final animal species to be scanned; the calculation method of the matching degree can be calculated by referring to the above formula.
  • the identification of animal species is realized by the comparison of physiological signals.
  • the comparison of physiological signals does not need to set marks on the animal body. It is sufficient to set a measuring device such as a wristband or a foot ring on the animal body. Non-invasive identification can be achieved.
  • the above S101 includes:
  • the scanning device obtains the body length parameter of the animal by identifying the image of the animal to be scanned, that is, the length of the animal from the head to the tail.
  • a camera located in the animal cabin takes pictures of the animal to be scanned to obtain a picture of the animal, and the picture is a static image of the animal to be scanned. After the picture is identified, the body length parameter of the animal is obtained according to the picture , and transmit the body length parameters to the terminal device with computing logic such as the server or the cloud.
  • the method for identifying the picture to obtain the animal body length parameter is to set scales with scales on both sides of the animal, so as to obtain the body length parameter directly by identifying the scale on the scale after the picture is formed. It can also mark the feature points on the body of the animal in advance, such as setting the first feature point on the head of the animal, and then setting multiple reflective points at equal intervals from the head to the tail. number to determine the body length parameters of animals.
  • a scale and feature points may also be set at the same time to identify the scale and feature points of the scale respectively, so as to verify the accuracy of the obtained body length parameters.
  • the body weight parameter of the animal is obtained by measuring the body weight of the animal.
  • a gravity sensor is used to read the body weight of the animal located in the animal cabin, so as to obtain the body weight parameter.
  • the scanning device can also obtain the body weight parameters of the animal to be scanned by the following method:
  • the breathing will be accompanied by a small range of movements, that is, the extension of the lungs during the breathing process will drive the body to perform a slight movement, and the slight movement will affect the weight measurement of the gravity sensor. time value.
  • the measurement error caused by slight movement will account for a larger proportion of the body weight. Taking one measurement improves the accuracy of your weight measurement.
  • the selection of the preset time is based on the respiratory rate of the animal.
  • the respiratory rate of each species of animals is different, such as the respiratory rate of rhesus monkeys is 30-50 times/min, the respiratory rate of dogs is 16-20 times/min, and the respiratory rate of cats is 20-30 times/min.
  • the preset time is different. For example, for animals with high breathing rates, the preset time interval is reduced, and for animals with low breathing rates, the preset time interval is increased.
  • the respiratory rate may be detected and counted by a device such as a monitor, a respiratory detector, and the like.
  • a four-corner membrane pressure sensor is used to measure body weight each time.
  • the body weight value of the animal is simultaneously measured by four four-corner membrane pressure sensors located around the animal, and the animal body weight value obtained by each measurement is the sum of the values collected by the four membrane pressure sensors.
  • the use of the four-corner membrane pressure sensor can ensure that a relatively accurate single measurement result can be obtained regardless of whether the animal is located in the center of the animal cabin.
  • the average value of the obtained body weight value is calculated, and the obtained result is the body weight parameter of the animal. That is, adding up the body weight values obtained for multiple times and then dividing by the number of times of collection is the body weight parameter of the animal. In one embodiment, the number of times the weight value is obtained is at least twice.
  • S503 compare the acquired body length parameters and body weight parameters of the animal with the pre-stored standard body length and standard body weight, respectively, to determine the type information of the animal.
  • the standard body lengths and standard weights corresponding to various animals are pre-stored in the terminal device. After obtaining the body length parameters and body weight parameters of the animals, the scanning device will acquire the body length parameters. Compare the body length and body weight parameters with multiple pre-stored standard body lengths and body weights, respectively, and find a group that is equal to the obtained body length parameters and body weight parameters from the multiple pre-stored standard body lengths and body weight parameters, that is, the standard body If the parameters of length and body length are equal, and the parameters of standard body weight and body weight are consistent, the animal species corresponding to the standard body length and standard body weight of this group is the species of animals in the animal cabin.
  • the process of obtaining the body length parameter of the animal to be scanned and obtaining the body weight parameter of the animal to be scanned by recognizing the image of the animal to be scanned is relatively simple, and can be realized only by simple identification, so that the obtained animal can be quickly
  • the body length parameters and body weight parameters of the system are compared with the pre-stored standard body length and body weight respectively, so as to quickly determine the type information of the animal and improve the efficiency of determining the type information of the animal.
  • the hair parameter of the animal can also be obtained.
  • the above method further includes: after acquiring the image of the animal to be scanned, also acquiring the animal's hair parameters, and determining the animal type information according to the animal's hair parameters, body length parameters and body weight parameters; at least one of the colors.
  • the hair parameter of the animal when identifying the image of the animal to be scanned, in addition to the body length parameter of the animal, the hair parameter of the animal is also obtained, wherein the hair parameter includes at least one of the length of the hair, the diameter of the hair, and the color of the hair.
  • the hair parameter includes at least one of the length of the hair, the diameter of the hair, and the color of the hair.
  • a sort of. There are also pre-stored standard hairs of a variety of animals in the terminal device, and the standard hair also includes at least one of the length of the hair, the diameter of the hair, and the color of the hair.
  • the scanning device can also acquire the animal's hair parameters, and the animal type information of the to-be-scanned animal can be determined according to the animal's hair parameters, body length parameters and body weight parameters.
  • the animal type information of the to-be-scanned animal can be determined according to the animal's hair parameters, body length parameters and body weight parameters.
  • body weight parameters and body length parameters of animals of the same family and different genera assist in distinguishing animal types to improve the accuracy of determining animal species information.
  • the animal scanning method includes: when a respiration-ECG protocol is selected, identifying whether a specified part of the animal body is shaved and affixed with electrode pads through the image of the animal to be scanned.
  • a protocol when a protocol is selected for scanning, it is first determined whether the selected protocol is related to respiration-ECG. If it is, the image of the animal to be scanned is captured by the camera, and the image of the animal to be scanned is directly observed with the naked eye. Or through automatic image recognition, identify and judge whether the designated part of the animal in the animal cabin is shaved and attached with electrode pads. Only when the designated part is shaved and attached with electrode pads, the respiration-ECG-related protocol will be executed, otherwise, first Perform shaving and padding. If the selected protocol is not related to respiration-ECG, the scan can be performed directly.
  • the scanning device uses the image of the animal to be scanned to identify whether the designated part of the animal body is shaved and attached with electrode pads, which can ensure the safety of the scanning device during the execution of the scanning protocol. , to make sure the scan goes smoothly.
  • the above S102 includes: the type of the animal cabin includes the corresponding The type of animal bed and the number of animal beds; obtain the occupancy of each animal bed in the animal cabin; identify the type of animals to be scanned on the occupied animal bed; determine whether the type of animal to be scanned is the same as the type of animal bed, if so , the type of the animal to be scanned matches the type of the animal cabin, otherwise it does not match.
  • the animal cabins include animal cabins of different types of animals, such as mouse cabins, rat cabins, and rabbit cabins.
  • an animal cabin may include multiple animal beds, for example: a single mouse cabin, two mouse cabins, four mouse cabins, a single rat cabin, two rat cabins, a single Rabbit cabin.
  • a registration page is dynamically set according to the number of beds to guide the user to enter the registration information, and the registration information of each scanning object is supported to facilitate the realization of the subsequent scanning process.
  • the animal cabin model is displayed, and the user selects different beds to enter the registration information of the corresponding scanning object.
  • the workstation detects an animal cabin (4 mouse animal cabin) that can place 4 mice at the same time, and the registration page displays 4 beds, that is, the upper right corner in Figure 3 has numbers "1, 2, 3, 4” circular icons, users can click the corresponding numbers in the circular icons to enter the registration information of the animals to be scanned in the corresponding beds.
  • the registration information is automatically verified to determine whether all the required registration information has been entered, and if not, a supplementary entry prompt will be given.
  • the basic registration information of the scanned object includes but is not limited to: name, position, gender, age, weight, length, species, and description;
  • the registration information of the injected drug includes but is not limited to: drug name, radionuclide, dose, injection date, injection time.
  • the registration system For animal cabins with multiple beds, before entering the registration information, first determine the occupancy of each bed, and set the bed to the unused state or the used state according to the occupancy of the bed. If one or some beds in the multi-bed animal cabin do not have scanning objects, you can set the beds as unused on the registration page. When a bed is set to be unused, the registration system will not check the scanning object information corresponding to the unused bed when checking the required registration information.
  • the judgment of the occupancy of the bed can also be implemented in combination with the corresponding physiological signals and/or corresponding images at the bed, and can be judged with reference to the animal survival judgment method. For example: if the physiological signal does not exist and the animal to be scanned is not identified in the image, it is judged that the animal is not placed in the scanning area, that is, the bed is not in use; if the physiological signal exists and the animal to be scanned can be identified in the image, then It is judged that the animal has been placed in the scanning area and is alive, that is, the bed is in the used state; if the physiological signal does not exist, but the animal to be scanned can be identified in the image, it is judged that the animal is dead, that is, the bed is in the used state, but cannot be scanned. Animal needs to be changed.
  • the animal scanning method includes:
  • the scanning device obtains the best scanning body position corresponding to the scanning protocol according to the scanning body position corresponding to the scanning protocol.
  • the scanning device may determine the best scanning body position corresponding to the scanning protocol among the plurality of scanning body positions corresponding to the scanning protocol.
  • S702 Acquire an image of the animal to be scanned, identify feature points in the image as actual feature points, and obtain the actual body position of the animal to be scanned by combining the coordinates of multiple actual feature points.
  • the actual body position is described by feature points, and the types of feature points used to describe the body position can be selected and set according to the characteristics of the animal to be scanned and the characteristics of the scanning area, including the feature points describing the position and the description
  • the feature points of the direction are two types of feature points. For example, when the head of a mouse needs to be scanned, its eyes can be selected as feature points to describe the head position, and then the ears and eyes can be selected to describe the head direction. Orientation for comprehensive positioning and accurate description of the head position of the mouse.
  • the scanning body position corresponding to the scanning protocol includes scanning feature points corresponding to a plurality of the above-mentioned actual feature points one-to-one.
  • S703 Calculate the sum of the distances between the actual feature points and the corresponding scanning feature points as the distance similarity.
  • the sum of the distances of all feature points is not calculated, but the sum of the distances of the feature points describing the position is calculated, which not only reduces the amount of calculation, but also eliminates the need for Unnecessary influence of the feature points describing the direction on the distance similarity calculation.
  • S706 Calculate the weighted sum of the distance similarity and the angle similarity to obtain the similarity between the actual body position and the scanned body position.
  • the influence of the position (including the distance) and the direction (including the angle) is considered, so that the calculated similarity can be calculated from the two Aspects describe the gap between the actual body position and the scanned body position.
  • This embodiment ensures that the scanning is performed after the actual body position and the scanned body position both reach a qualified similarity in these two aspects.
  • the sum of the distances between the feature points of its two eyes can be selected as the distance similarity, and then the line connecting the intersection of the tail and the body and the two eyes can be selected as the feature line, and the two The sum of the angles of the feature lines is used as the angle similarity.
  • the solid line in FIG. 8 shows the scanning body position of the mouse, and the dotted line shows the actual body position of the mouse.
  • Points A1, A2, and A3 are all scanning feature points
  • A1 and A2 are the eyes of the mouse
  • A3 is the intersection of the mouse tail and the body.
  • Points B1, B2 and B3 are all actual feature points, B1 and B2 are the eyes of the mouse, and B3 is the intersection of the tail and the body of the mouse.
  • Calculate the distance AB1 between the scanning feature point A1 and the actual feature point B1 calculate the distance AB2 between the scanning feature point A2 and the actual feature point B2, and use AB1+AB2 as the distance similarity.
  • Connect A1 and A3 to obtain the first scanning characteristic line connect A2 and A3 to obtain the second scanning characteristic line; connect B1 and B3 to obtain the first actual characteristic line, and connect B2 and B3 to obtain the second actual characteristic line.
  • Calculate the angle value between the first scan feature line and the first actual feature line calculate the angle value between the second scan feature first and the second actual feature line, and use the sum of the two angle values as the angle similarity Spend.
  • the distance weight and the angle weight can be set according to the type of the animal to be scanned and the degree of requirements for the position and direction of the scanning area, and the sum of the distance weight and the angle weight is 1.
  • S707 determine whether the similarity is greater than the set threshold, if not, output body position adjustment parameters to guide the body position adjustment, and perform scanning until the similarity between the actual body position and the scanned body position is greater than the set threshold.
  • the output body position adjustment parameters are used to guide the body position adjustment, including: outputting the distance between each actual feature point and the corresponding scan feature point, and the angle between each actual feature line and the corresponding scan feature line as the body position adjustment parameters.
  • the adjustment can be performed manually, preferably by an automatic method. For example, an animal bed including an adjustment mechanism is set, and after the animal is fixed on the bed by the fixing component, the parameters of the adjustment mechanism are corrected according to the body position adjustment parameters, and the animal body position is automatically adjusted.
  • the adjustment mechanism includes a rotation mechanism and a translation mechanism.
  • the rotation mechanism is connected to the corresponding fixed component and is used to drive the corresponding fixed component to rotate to adjust the orientation direction of the scanning area of the animal to be scanned.
  • the translation mechanism is connected to the corresponding fixed component for driving.
  • the corresponding fixing components are moved to adjust the setup position of the scanning area of the animal to be scanned.
  • the influences of the position (including the distance) and the direction (including the angle) are considered, so that the calculated similarity can be obtained from two aspects. Describe the difference between the actual body position and the scanned body position, and then judge whether the similarity is greater than the set threshold. If the similarity is less than the set threshold, output the body position adjustment parameters to guide the body position adjustment until the actual body position and the scanned body position are between Scanning is performed when the similarity is greater than the set threshold, to ensure that the actual body position and the scanned body position have reached a qualified similarity in these two aspects before scanning.
  • a camera is provided on the animal cabin and/or on the body of the animal imaging device. Through the camera, the image of the animal to be scanned is obtained.
  • the camera can be set on the animal cabin, also can be set on the animal imaging device body, or can be set on the animal cabin and the animal imaging device body at the same time. It can be understood that the camera disposed on the animal cabin includes being disposed on the inside or the outer surface of the animal cabin, as long as it is attached to the structure of the animal cabin, the image of the animal to be scanned in the animal cabin can be acquired.
  • the camera is arranged on the body of the animal imaging device, either on the outer surface of the body of the animal imaging device, or in the scanning hole of the body of the animal imaging device.
  • the animal imaging device body 4 is provided with a camera 1, which may be a surveillance camera, and the animal scanning method includes: acquiring the distance between the animal cabin 2 and the camera 1, and adjusting the distance according to the distance The focal length of camera 1 to achieve the focus of the camera.
  • the animal imaging equipment when the animal imaging equipment is working, in order to facilitate the experimenter to observe the animal state, the animal imaging equipment is integrated with a monitoring device, that is, the camera in the embodiment of the present invention, and the camera is used for real-time observation of animals undergoing experiments.
  • the camera is set on the animal imaging device body, the initial position of the animal cabin is outside the animal imaging device, and can be driven and pushed into the animal imaging device body, so that the animal imaging device scans the animal placed on the animal cabin.
  • the camera is monitoring animals, in order to ensure the clarity of the surveillance video, the camera needs to have a suitable focal length so that a suitable image can be obtained.
  • the focal length of the camera is related to the distance between the camera and the object to be photographed and the image distance of the camera.
  • the focal length of the camera is adjusted in real time by obtaining the distance between the camera and the animal cabin.
  • the camera is a zoom optical camera.
  • the scanning device obtains the distance between the animal cabin and the camera, and adjusts the focal length of the camera according to the distance between the animal cabin and the camera, so as to realize the focusing of the camera.
  • the distance between the animal cabin and the camera obtained by the scanning device may be obtained by the following steps:
  • Step A obtain the initial distance between the animal cabin and the camera.
  • Step B acquiring real-time data of the encoder on the animal cabin driving device, and obtaining the real-time itinerary of the animal cabin according to the real-time data of the encoder; wherein, the animal cabin driving device is used for driving the animal cabin to move.
  • Step C Calculate the real-time distance between the animal cabin and the camera according to the initial distance and the real-time itinerary.
  • the animal cabin is reset (returning the position of the animal cabin to the initial position), and the initial position of the animal cabin before the animal imaging experiment is a preset position, and the camera The position of the camera is fixed, and the initial distance between the animal cabin and the camera is fixed, which can be obtained directly through the installation parameters during installation, which is simple and convenient.
  • the animal cabin is slowly approached to the body of the animal imaging device.
  • the real-time travel of the animal cabin is the travel distance of the animal cabin from the initial position, wherein the animal cabin is driven by the driving device,
  • An encoder is installed on the driving device, and the data of the encoder reflects the motion data of the driving device, and the motion data of the driving device corresponds to the stroke of the animal cabin in real time.
  • the method for obtaining the real-time itinerary of the animal cabin is:
  • the real-time data of the encoder on the animal cabin driving device is acquired, and the stroke of the animal cabin is obtained according to the real-time data of the encoder; wherein, the animal cabin driving device is used to drive the movement of the animal cabin.
  • the driving device is a motor.
  • the real-time distance between the animal cabin and the camera can be calculated according to the principle of kinematics. Specifically, the distance between the animal cabin and the camera is The calculation method of the real-time distance is: calculate the difference between the initial distance between the animal cabin and the camera and the real-time travel of the animal cabin, and use the difference as the real-time distance between the animal cabin and the camera.
  • the motion of the animal cabin is a motion close to the camera, so the real-time distance between the animal cabin and the camera is the value obtained by subtracting the real-time travel from the initial distance.
  • the camera can be arranged on the side of the animal cabin away from the body of the animal imaging device.
  • the real-time distance between the camera and the animal cabin is the sum of the initial distance and the real-time travel. Therefore, the specific real-time distance
  • the calculation method is determined according to the position of the camera, which is not limited in the present invention, but it should be understood that no matter where the position of the camera is set, the calculation method of the real-time distance should be consistent with the initial distance between the animal cabin and the camera and the animal cabin. real-time itinerary.
  • the target focal length of the camera can be calculated according to the real-time distance and the image distance of the camera, and the real-time focal length of the camera can be adjusted according to the target focal length to realize the focusing of the camera.
  • the distance is a fixed parameter.
  • the object distance of the camera changes with the real-time travel of the animal cabin, and has a linear relationship.
  • the object distance of the camera can be directly calculated through the real-time travel of the animal cabin obtained above.
  • the focal length can be calculated from the lens imaging formula. It should be noted that, in this embodiment, the real-time distance is the distance between the imaging point of the camera and a certain fixed point of the animal cabin.
  • the fixed point is the front end of the animal cabin.
  • the fixed point can also be selected from the rear end of the animal cabin or a certain point in the middle.
  • the distance between the front end of the animal cabin and the camera in the forward direction is denoted as l 0
  • the stroke of the animal cabin is denoted as d
  • the real-time distance between the front end of the animal cabin and the imaging point of the camera is is l 0 -d. Therefore, please also refer to FIG. 10, which is a physical model diagram of a preferred embodiment of camera lens imaging. As can be seen from FIG.
  • the calculation method to obtain the target focal length of the camera is as follows: Among them, f represents the target focal length of the camera, i represents the image distance of the camera, and o represents the object distance of the camera. Therefore, when performing animal scanning experiments, it is only necessary to monitor the travel of the animal cabin in real time, and then the target focal length of the camera can be quickly calculated according to the above formula, which is simple and convenient. Furthermore, since the camera is a zoom optical camera, it only needs to zoom according to the target focal length to ensure that the camera can capture a clear image without additional ranging, and the system is simple and accurate.
  • the focal length of the camera can be adjusted according to the distance between the animal cabin and the camera, so that the focusing of the camera can be achieved, and the camera can ensure that the camera captures a clear image when the camera is in focus.
  • the monitoring camera can also be used to monitor the animals to be scanned in real time, so that the staff can obtain the conditions of the animals on the animal cabin in real time.
  • FIGS. 2-7 are shown in sequence according to the arrows, these steps are not necessarily executed in the sequence shown by the arrows. Unless explicitly stated herein, the execution of these steps is not strictly limited to the order, and these steps may be performed in other orders. Moreover, at least a part of the steps in FIGS. 2-7 may include multiple steps or multiple stages. These steps or stages are not necessarily executed and completed at the same time, but may be executed at different times. The execution of these steps or stages The order is also not necessarily sequential, but may be performed alternately or alternately with other steps or at least a portion of the steps or phases within the other steps.
  • an animal scanning device including: a first acquiring unit, a judging unit, a matching unit and a scanning unit, wherein:
  • a first acquisition unit used to acquire the type of the animal to be scanned
  • the judgment unit is used to identify the type of the animal cabin where the animal to be scanned is located, and to determine whether the type of the animal to be scanned matches the type of the animal cabin;
  • a matching unit configured to match and present a corresponding scanning protocol according to the type of the animal to be scanned if the type of the animal to be scanned matches the type of the animal cabin;
  • the scanning unit is used for scanning according to a corresponding scanning protocol, or scanning according to a user-defined scanning protocol.
  • the animal scanning device provided in this embodiment can execute the above method embodiments, and its implementation principle and technical effect are similar, and details are not repeated here.
  • the above-mentioned apparatus further includes: a second acquisition unit and a third acquisition unit, wherein:
  • the second acquiring unit is used for acquiring the image of the animal to be scanned.
  • the third acquiring unit is configured to acquire the type of the animal to be scanned according to the image of the animal to be scanned, and/or monitor the animal to be scanned in real time according to the image of the animal to be scanned.
  • the animal scanning device provided in this embodiment can execute the above method embodiments, and its implementation principle and technical effect are similar, and details are not repeated here.
  • the above-mentioned device further includes: a first judgment unit, wherein:
  • the first judging unit is used for judging whether the user-defined scanning protocol matches the type of the animal to be scanned, and if not, prompting to modify the user-defined scanning protocol.
  • the animal scanning device provided in this embodiment can execute the above method embodiments, and its implementation principle and technical effect are similar, and details are not repeated here.
  • the above-mentioned device further includes: a second judgment unit, wherein:
  • the second judging unit is used to obtain the physiological signal and real-time image of the animal to be scanned, and determine whether the animal to be scanned is alive in combination with the physiological signal and the real-time image; if not, output a reminder for animal sample replacement.
  • the animal scanning device provided in this embodiment can execute the above method embodiments, and its implementation principle and technical effect are similar, and details are not repeated here.
  • the above-mentioned first acquisition unit is used to set the physiological signal range of different types of animals, and establish a physiological signal database; match the animal type corresponding to the physiological signal in the physiological signal database to obtain the type of the animal to be scanned.
  • the animal scanning device provided in this embodiment can execute the above method embodiments, and its implementation principle and technical effect are similar, and details are not repeated here.
  • the above-mentioned first obtaining unit is used to obtain the body length parameter of the animal by identifying the image; obtain the body weight parameter of the animal to be scanned; and compare the obtained body length parameter and body weight parameter with the pre-stored parameters respectively The standard body length and standard body weight are compared to determine the species information of the animal.
  • the animal scanning device provided in this embodiment can execute the above method embodiments, and its implementation principle and technical effect are similar, and details are not repeated here.
  • the foregoing apparatus further includes: a fourth obtaining unit, wherein:
  • the fourth obtaining unit is used to obtain the animal's hair parameters after obtaining the image of the animal to be scanned, and determine the animal type information according to the animal's hair parameters, body length parameters and body weight parameters; the hair parameters include the length of the hair, the diameter of the hair, the At least one of the colors of the hair.
  • the animal scanning device provided in this embodiment can execute the above method embodiments, and its implementation principle and technical effect are similar, and details are not repeated here.
  • the above-mentioned first acquisition unit is used to set scales with scales on both sides of the animal, and obtain body length parameters and/or mark feature points on the body of the animal by identifying the scales on the scales, Determine the body length parameters of animals by identifying feature points.
  • the animal scanning device provided in this embodiment can execute the above method embodiments, and its implementation principle and technical effect are similar, and details are not repeated here.
  • the above-mentioned first acquisition unit is configured to acquire multiple body weight values of the animal to be scanned; and based on the multiple body weight values, obtain the body weight parameters of the to-be-scanned animal.
  • the animal scanning device provided in this embodiment can execute the above method embodiments, and its implementation principle and technical effect are similar, and details are not repeated here.
  • the above-mentioned device further includes: an identification unit, wherein:
  • the identification unit is used to identify whether the specified part of the animal body is shaved and attached with electrode pads through the image of the animal to be scanned when the respiration-ECG protocol is selected.
  • the animal scanning device provided in this embodiment can execute the above method embodiments, and its implementation principle and technical effect are similar, and details are not repeated here.
  • the type of the animal cabin includes the corresponding animal bed type and the number of animal beds, and the above judgment unit is used to obtain the occupancy status of each animal bed in the animal cabin; Type identification of the animals to be scanned on the animal bed; determine whether the type of the animal to be scanned is the same as the type of the animal bed. If so, the type of the animal to be scanned matches the type of the animal cabin, otherwise it does not match.
  • the animal scanning device provided in this embodiment can execute the above method embodiments, and its implementation principle and technical effect are similar, and details are not repeated here.
  • the foregoing apparatus further includes: a fifth obtaining unit, a sixth obtaining unit, a first calculating unit, a seventh obtaining unit, a second calculating unit, a third calculating unit, and a third judging unit unit, where:
  • the fifth acquisition unit is used for acquiring the best scanning body position corresponding to the scanning protocol.
  • the sixth acquisition unit is used for acquiring the image of the animal to be scanned, and identifying the feature points in the image as actual feature points, and combining the coordinates of multiple actual feature points to obtain the actual body position of the animal to be scanned; the scanned body position includes a plurality of actual feature points and One-to-one corresponding scanning feature points.
  • the first calculation unit is configured to calculate the sum of the distances between each actual feature point and the corresponding scanning feature point as the distance similarity.
  • the seventh obtaining unit is used for connecting any two actual feature points to obtain a plurality of actual feature lines, and connecting any two scanning feature points to obtain a plurality of scanning feature lines.
  • the second calculation unit is configured to calculate the sum of the angles between each actual feature line and the corresponding scanning feature line as the angle similarity.
  • the third calculation unit is used for calculating the weighted sum of the distance similarity and the angle similarity to obtain the similarity between the actual body position and the scanned body position.
  • the third judging unit is used for judging whether the similarity is greater than the set threshold, if not, output the body position adjustment parameters to guide the body position adjustment, and scan until the similarity between the actual body position and the scanned body position is greater than the set threshold.
  • the animal scanning device provided in this embodiment can execute the above method embodiments, and its implementation principle and technical effect are similar, and details are not repeated here.
  • the foregoing apparatus further includes: an eighth obtaining unit, wherein:
  • the eighth acquisition unit is used to acquire the distance between the animal cabin and the camera, and adjust the focal length of the camera according to the distance, so as to realize the focus of the camera.
  • the animal scanning device provided in this embodiment can execute the above method embodiments, and its implementation principle and technical effect are similar, and details are not repeated here.
  • the above-mentioned eighth obtaining unit is used to obtain the initial distance between the animal cabin and the camera; obtain the real-time data of the encoder on the driving device of the animal cabin, and obtain the animal according to the real-time data of the encoder The real-time travel of the cabin; wherein, the animal cabin driving device is used to drive the movement of the animal cabin; the real-time distance between the animal cabin and the camera is calculated according to the initial distance and the real-time travel.
  • the animal scanning device provided in this embodiment can execute the above method embodiments, and its implementation principle and technical effect are similar, and details are not repeated here.
  • Each module in the above-mentioned animal scanning device can be implemented in whole or in part by software, hardware and combinations thereof.
  • the above modules can be embedded in or independent of the processor in the computer device in the form of hardware, or stored in the memory in the computer device in the form of software, so that the processor can call and execute the operations corresponding to the above modules.
  • an animal scanning system includes the animal scanning device 5 described in any of the above embodiments, and further includes an animal cabin 6, an image acquisition device 7, a physiological Signal detection device 8; wherein:
  • the animal cabin 6 is arranged on the bed and is used to place the animals to be scanned;
  • the image acquisition device 7 is used to acquire the image of the animal to be scanned
  • the physiological signal detection device 8 is used to obtain the physiological signal of the animal to be scanned;
  • the animal scanning device 5 is used for scanning the animal to be scanned.
  • a scanning bed is provided in the animal cabin, and the animal to be scanned can be fixed on the scanning bed.
  • the image acquisition device may include the camera in any of the above embodiments, and is used to capture images of the animals to be scanned.
  • the physiological signal detection device is set according to the physiological signal to be detected. For example, if the heartbeat of an animal needs to be detected, an ECG monitor is used.
  • the animal cabin is provided with a data interface for transmitting images and physiological signals to the animal scanning device.
  • the animal scanning device receives the above-mentioned various signals, and implements scanning by using the animal scanning method provided by the present invention.
  • the animal scanning system provided by some embodiments of the present application can execute the foregoing method embodiments, and the implementation principles and technical effects thereof are similar, and details are not described herein again in this embodiment.
  • the foregoing animal scanning system further includes a light source and an animal imaging device body, wherein,
  • the animal imaging device body has a scanning hole, the animal cabin can move along the axial direction of the scanning hole, and the light source is fixedly installed on the animal imaging device body.
  • the light source follows the rotation of the camera to provide necessary light for the camera to capture the image of the animal.
  • the body of the animal imaging device may be a frame of the animal imaging device.
  • the animal imaging device is a device for animal scanning imaging, including CT, MR, SPECT, PET, and or a combination of two or more modalities.
  • the animal scanning system provided in this embodiment can execute the foregoing method embodiments, and the implementation principles and technical effects thereof are similar, and details are not described herein again in this embodiment.
  • the image acquisition device is provided on the animal cabin and/or on the body of the animal imaging device.
  • the animal scanning system provided in this embodiment can execute the foregoing method embodiments, and the implementation principles and technical effects thereof are similar, and details are not described herein again in this embodiment.

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Abstract

本申请公开了一种动物扫描方法、装置和系统，该方法包括：获取待扫描动物的种类；识别待扫描动物所在动物舱的类型，判断所述待扫描动物的种类与所述动物舱的类型是否匹配；如果所述待扫描动物的种类与所述动物舱的类型匹配，则根据待扫描动物的种类匹配并呈现对应的扫描协议；根据对应的扫描协议进行扫描，或根据用户自定义的扫描协议进行扫描。该方法不需要人工录入动物的基本信息，扫描协议匹配后呈现给用户，如果用户不满意匹配的扫描协议，可以进行扫描协议的自定义，从而使得扫描协议选择的灵活性更强。同时，能够在确保动物与动物舱匹配的前提下再进行后续扫描协议的确定及扫描过程，实现了更高自动化程度的动物扫描过程。

Description

动物扫描方法、装置和系统
相关申请
本申请的相关申请分别要求于2020年12月31日申请的，申请号为202011636936.5，名称为“一种基于动物识别的影像扫描方法、装置及系统”；于2020年12月31日申请的，申请号为202011636941.6，名称为“一种动物扫描方法、装置及系统”；于2020年12月31日申请的，申请号为202011633122.6，名称为“动物成像设备及其监控摄像头对焦方法及视频监控方法”，的中国专利申请的优先权，在此将其全文引入作为参考。
技术领域
本申请涉及医学影像技术领域，更具体的说，涉及一种动物扫描方法、装置和系统。
背景技术
在对动物进行临床前影像扫描前，需要先设置相应的扫描协议，扫描协议确定后，根据扫描协议对应的最佳的扫描体位对动物进行摆位，然后进行扫描。在对动物进行摆位时，为了避免动物乱动，通常会对动物进行麻醉，然后固定动物的体位。
目前，对于动物种类的判断采用人为识别；对于动物舱的类型，也是根据操作人员的经验去判断。在进行扫描前，需要人工录入动物的基本信息，在进行扫描协议的设置选择时，通常采用人为手动选取的方式，这种方式效率较低、容易出错，不适合经验不足的操作人员。
发明内容
本申请一些实施例中提供一种动物扫描方法，所述方法包括：
获取待扫描动物的种类；
识别待扫描动物所在动物舱的类型，判断所述待扫描动物的种类与所述动物舱的类型是否匹配；
如果所述待扫描动物的种类与所述动物舱的类型匹配，则根据待扫描动物的种类匹配并呈现对应的扫描协议；
根据对应的扫描协议进行扫描，或根据用户自定义的扫描协议进行扫描。
在其中一个实施例中，所述方法还包括：
获取所述待扫描动物的图像；
根据所述待扫描动物的图像获取所述待扫描动物的种类，和/或，根据所述待扫描动物的图像对所述待扫描动物实时监控。
在其中一个实施例中，所述根据用户自定义的扫描协议进行扫描之前，所述方法还包括：判断所述用户自定义的扫描协议是否与所述待扫描动物的种类匹配，若不匹配，则提示对所述用户自定义的扫描协议进行修改。
在其中一个实施例中，所述方法还包括：
获取所述待扫描动物的生理信号以及实时图像，结合所述生理信号以及所述实时图像判断所述待扫描动物是否存活；
若否，则输出动物样本更换提醒。
在其中一个实施例中，所述获取待扫描动物的种类，包括：
设置不同种类动物的生理信号范围，建立生理信号数据库；
在所述生理信号数据库中匹配所述生理信号对应的动物种类，得到所述待扫描动物的种类。
在其中一个实施例中，所述获取待扫描动物的种类，包括：
通过识别所述图像得到动物的体长参数；
获取待扫描动物的体重参数；
将获取到的动物的体长参数及体重参数分别与预存的标准体长及标准体重进行比对，确定动物的种类信息。
在其中一个实施例中，所述方法还包括：
获取待扫描动物的图像后，还获取动物的毛发参数，根据动物的毛发参数、体长参数及体重参数确定动物种类信息；毛发参数包括毛发的长度、毛发的直径、毛发的颜色中至少一种。
在其中一个实施例中，所述通过识别所述图像得到动物的体长参数包括：
在动物的两侧设置带有刻度的标尺，通过识别标尺上的刻度来得到体长参数和/或在动物的身上标记特征点，通过识别特征点确定动物的体长参数。
在其中一个实施例中，所述获取待扫描动物的体重参数包括：
获取所述待扫描动物的多个体重数值；及
基于多个体重数值，得到所述待扫描动物的体重参数。
在其中一个实施例中，所述方法还包括：
在选择呼吸-心电协议时，通过所述待扫描动物的图像识别动物身体的指定部位是否剃 毛并贴有电极片。
在其中一个实施例中，所述识别待扫描动物所在动物舱的类型，判断所述待扫描动物的种类与所述动物舱的类型是否匹配，包括：
所述动物舱的类型包括所对应的动物床位种类以及动物床位数量；
获取所述动物舱内各动物床位的占用情况；
对处于占用状态的动物床位上的待扫描动物进行种类识别；
判断待扫描动物的种类与所述动物床位种类是否相同，如果是，则待扫描动物的种类与所述动物舱的类型匹配，否则不匹配。
在其中一个实施例中，所述根据对应的扫描协议进行扫描，或根据用户自定义的扫描协议进行扫描之前，所述方法还包括：
获取所述扫描协议对应的最佳的扫描体位；
获取待扫描动物的图像，并识别所述图像中特征点作为实际特征点，结合多个所述实际特征点的坐标得到所述待扫描动物的实际体位；
所述扫描体位包括与多个所述实际特征点一一对应的扫描特征点；
计算各所述实际特征点与相应的扫描特征点之间的距离之和，作为距离相似度；
连接任意两个所述实际特征点，得到多条实际特征线，连接任意两个所述扫描特征点，得到多条扫描特征线；
计算各所述实际特征线与对应的扫描特征线之间的角度之和，作为角度相似度；
计算所述距离相似度与所述角度相似度的加权和，得到所述实际体位与所述扫描体位之间的相似度；
判断所述相似度是否大于设定阈值，如果否，则输出体位调整参数用于指导体位调整，直至实际体位与所述扫描体位之间的相似度大于设定阈值时再进行扫描。
在其中一个实施例中，所述获取所述待扫描动物的图像之前，所述方法还包括：
获取所述动物舱与摄像头的距离，根据所述距离调节所述摄像头的焦距，以实现所述摄像头的对焦。
在其中一个实施例中，所述获取所述动物舱与摄像头的距离，包括：
获取所述动物舱与所述摄像头的初始距离；
获取动物舱驱动装置上的编码器的实时数据，根据所述编码器的实时数据得到所述动物舱的实时行程；其中，所述动物舱驱动装置用于驱动所述动物舱运动；
根据所述初始距离以及所述实时行程计算出所述动物舱与摄像头的实时距离。
本申请一些实施例中提供一种动物扫描装置，包括：
第一获取单元，用于获取待扫描动物的种类；
判断单元，用于识别待扫描动物所在动物舱的类型，判断所述待扫描动物的种类与所述动物舱的类型是否匹配；
匹配单元，用于如果所述待扫描动物的种类与所述动物舱的类型匹配，则根据待扫描动物的种类匹配并呈现对应的扫描协议；
扫描单元，用于根据对应的扫描协议进行扫描，或根据用户自定义的扫描协议进行扫描。
本申请一些实施例中提供一种动物扫描系统，包括如第二方面所述的动物扫描装置，还包括动物舱、图像获取装置、生理信号检测装置；
所述动物舱，设置于床体上，用于放置待扫描动物；
所述图像获取装置用于获取待扫描动物的图像；
所述生理信号检测装置用于获取待扫描动物的生理信号；
所述动物扫描装置用于对待扫描动物进行扫描。
在其中一个实施例中，还包括光源和动物成像设备本体，其中，
所述动物成像设备本体具有一扫描孔，所述动物舱可沿所述扫描孔的轴向运动，所述光源固定安装在所述动物成像设备本体上。
在其中一个实施例中，所述图像获取装置设置于所述动物舱上和/或设置于动物成像设备本体上。
附图说明
为了更清楚地说明本申请实施例或现有技术中的技术方案，下面将对实施例或现有技术描述中所需要使用的附图作简单地介绍，显而易见地，下面描述中的附图仅仅是本申请的实施例，对于本领域普通技术人员来讲，在不付出创造性劳动的前提下，还可以根据公开的附图获得其他的附图。
图1为根据本申请一些实施例提供的一种动物扫描方法的流程示意图；
图2为根据本申请一些实施例提供的一种动物扫描方法的流程示意图；
图3为根据本申请一些实施例提供的一种动物扫描方法的流程示意图；
图4为根据本申请一些实施例提供的一种动物扫描方法的流程示意图；
图5为根据本申请一些实施例提供的一种动物扫描方法的流程示意图；
图6为根据本申请一些实施例提供的动物扫描方法的动物舱注册信息输入界面图；
图7为根据本申请一些实施例提供的一种动物扫描方法的流程示意图；
图8为根据本申请一些实施例提供的动物扫描方法的相似度计算示意图；
图9为根据本申请一些实施例提供的动物成像设备的视频监控系统的结构示意图；
图10为根据本申请一些实施例提供的摄像头透镜成像的物理模型示意图；
图11为根据本申请一些实施例提供的动物扫描装置的结构框图；
图12为根据本申请一些实施例提供的动物扫描系统的架构图。
附图标记说明：
1：摄像头；2：动物舱；3：光源；4：动物成像设备本体；5：动物扫描装置；
6：动物舱；61：数据接口；7：图像获取装置；8：生理信号检测装置。
具体实施方式
下面将结合本申请实施例中的附图，对本申请实施例中的技术方案进行清楚、完整地描述，显然，所描述的实施例仅仅是本申请一部分实施例，而不是全部的实施例。基于本申请中的实施例，本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例，都属于本申请保护的范围。
参见图1，其为根据本申请的一些实施例公开的一种动物扫描方法流程图，该方法包括步骤：
S101，获取待扫描动物的种类。
在一些实施例中，扫描设备可以获取待扫描动物的图像，根据待扫描动物的图像获取待扫描动物的种类。在一些实施例中，扫描设备可以通过摄像头拍摄待扫描动物的图像，例如，该摄像头可以为视频摄像头或者高清相机。
S102，识别待扫描动物所在动物舱的类型，判断待扫描动物的种类与动物舱的类型是否匹配。
在一些实施例中，扫描时将待扫描动物的扫描图像等数据传输至动物舱外的扫描终端，动物舱上设置有数据传输接口，可以通过数据传输接口的类型以及所传输的数据类型识别动物舱的类型。在动物的种类和动物舱的类型识别完成后，即可完成动物舱与动物的匹配判断，如果动物舱与动物不匹配，则提示用户进行动物更换；如果动物舱与动物匹配，则可以根据动物种类匹配出对应的扫描协议。
S103，如果待扫描动物的种类与动物舱的类型匹配，则根据待扫描动物的种类匹配并呈现对应的扫描协议。
在一些实施例中，扫描协议的选择可以采用自动匹配或用户自定义两种方式实现。扫描协议的自动匹配可以通过建立扫描协议库的方式实现，针对每一种动物的每一种扫描区 域建立相对应的扫描协议，根据待扫描动物的种类和扫描区域在扫描协议库中进行自动匹配即可。如果用户觉得自动匹配得到的扫描协议有误或匹配度不高，或者有经验的操作者认为自动匹配的扫描协议需要修改时，可以进行扫描协议的自定义设置。
S104，根据对应的扫描协议进行扫描，或根据用户自定义的扫描协议进行扫描。
扫描协议确定后，即可完成后续扫描过程。在一些实施例中，扫描设备可以根据与待扫描动物的种类匹配的扫描协议进行扫描，也可以根据用户自定义的扫描协议进行扫描。
根据本申请的一些实施例，在进行动物扫描前先进行动物种类的识别，以便根据动物种类进行扫描协议的自动匹配，在进行扫描协议匹配时，不需要人工录入动物的基本信息，扫描协议匹配后呈现给用户，如果用户不满意匹配的扫描协议，则可以进行扫描协议的自定义，从而使得扫描协议选择的灵活性更强。同时，在扫描协议匹配之前，对动物与动物舱的匹配情况进行了自动判断，在确保动物与动物舱匹配的前提下再进行后续扫描协议的确定及扫描过程，进一步提高扫描过程的自动化程度。
根据本申请的一些实施例，在扫描之前和/或扫描过程中，获取待扫描动物的图像，根据待扫描动物的图像获取待扫描动物的种类，和/或，根据待扫描动物的图像对待扫描动物实时监控。扫描设备在对待扫描动物进行扫描的过程中还可以对待扫描动物进行实时监控，在一些实施例中，如图2所示，动物扫描方法包括：
S201，获取待扫描动物的图像。
在一些实施例中，扫描设备获取待扫描动物的图像。在一些实施例中，扫描设备可以通过自身的摄像头获取待扫描动物的图像，也可以通过与摄像头的通信连接，从摄像头中获取采集的待扫描动物的图像。
S202，根据待扫描动物的图像获取待扫描动物的种类，和/或，对待扫描动物实时监控。
对于根据待扫描动物的图像获取待扫描动物的种类的场景，在一些实施例中，扫描设备可以根据待扫描动物的图像获取待扫描动物的体长参数，根据待扫描动物的体长参数获取待扫描动物的种类。需要说明的是，这里的待扫描动物的图像为待扫描动物的静态图像。该静态图像可以由具有摄像头的光学相机在扫描前拍摄得到，也可以由具有摄像头的高清摄像机获取。对于根据待扫描动物的图像对待扫描动物实时监控的场景，在一些实施例中，扫描设备可以根据待扫描动物的图像对待扫描动物实时监控。需要说明的是，这里的待扫描动物的图像为待扫描动物的实时图像。该实时图像可以由具有摄像头的高清摄像机在扫描过程中实时获取。
本实施例中，根据待扫描动物的图像能够快速地获取待扫描动物的种类，根据待扫描动物的图像在进行动物成像实验时能够对待扫描动物进行实时视频监控，以便工作人员实 时获取动物舱上的动物的情况。
在上述根据用户自定义的扫描协议进行扫描之前，还需要判断用户自定义的扫描协议是否与待扫描动物的种类匹配，在上述实施例的基础上，在一个实施例中，上述方法还包括：判断用户自定义的扫描协议是否与待扫描动物的种类匹配，若不匹配，则提示对用户自定义的扫描协议进行修改。
本申请一些实施例中，扫描协议匹配后，可将扫描协议及其所对应的最佳的扫描体位输出值在扫描终端进行显示，以便用户查看，同时指导动物的摆位。在扫描终端对扫描协议及其对应的最佳的扫描体位进行显示后，用户可以在扫描终端对匹配的扫描协议和扫描体位进行人工检查，如果用户觉得自动匹配的结果并不合适，也可以不选择自动推荐的扫描协议、最佳的扫描体位，而是人工进行扫描协议和扫描体位的设置，或者对匹配的扫描协议和扫描体位进行修改。优选采用体态模型图的方式对扫描体位进行显示，在扫描终端显示动物的体态模型图，用户鼠标移动至动物的体态模型图上某一位置时，体态模型图上相应的身体部位图标会自动凸出高亮显示，同时匹配当前体态模型图的扫描协议会以列表形式进行显示，以供用户选择，其中自动匹配推荐出的最佳的扫描协议与最佳的扫描体位也会呈高亮显示，便于操作人员对比修改。根据不同种类的动物，支持不同的体态模型图及扫描协议：如小鼠支持全身扫描、脑部扫描等，犬类支持单/多床、胸部、脑部等扫描。
本实施例中，扫描设备通过判断用户自定义的扫描协议是否与待扫描动物的种类匹配，在用户自定义的扫描协议与待扫描动物的种类不匹配的情况下，能够提示扫描设备对用户自定义的扫描协议进行修改，确保对待扫描动物进行扫描的扫描协议的准确性。
在本申请一些实施例中，如图3所示，动物扫描方法包括：
S301，获取待扫描动物的生理信号以及实时图像，结合生理信号以及实时图像判断待扫描动物是否存活。
在本申请一些实施例中，针对可以同时容纳多个动物的多动物舱扫描的情况，在对待扫描动物进行扫描之前或者扫描过程中，可以结合待扫描动物的生理信号和动物实时图像两个信号判断动物的存活状态，避免有一些动物因对麻醉药物不耐受或其它原因出现死亡，而用户没有及时发现，出现无效扫描的情况。在本申请一个实施例中，如果生理信号不存在，且动物实时图像中没有识别到待扫描的动物，则判断动物没有放入扫描区域；如果生理信号存在，且动物实时图像中可以识别到待扫描动物，则判断动物已经放入扫描区域且存活；如果生理信号不存在，但是动物实时图像中可以识别到待扫描动物，则判断动物死亡。在待扫描动物处于存活状态的情况下，可以继续扫描过程。当然，在一些实施例中，例如对于单次扫描只能容纳单个动物的动物舱，也可以单独采用生理信号或者实时图 像判断待扫描动物是否存活，或者通过实时图像获取生理信号(例如根据实时图像获取呼吸信号)来判断待扫描动物是否存活。
S302，若否，则输出动物样本更换提醒。
具体地，若扫描设备结合待扫描动物的生理信号以及实时图像，确定待扫描动物死亡，则输出动物样本更换提醒，及时地更换已经死亡的动物样本。
本实施例中，扫描设备通过获取待扫描动物的生理信号以及实时图像，能够结合待扫描动物的生理信号以及实时图像判断待扫描动物是否存活，避免有一些动物因对麻醉药物不耐受或其它原因出现死亡，而用户没有及时发现，出现无效扫描的情况。
在上述获取待扫描动物的种类的场景中，在一些实施例中，可以直接通过获取的图像进行图像识别获取待扫描动物的种类。在一些实施例中，也可以通过待扫描动物的生理信号获取待扫描动物的种类，也可以根据待扫描动物的体长参数和体重参数获取待扫描动物的种类。
在一些实施例中，如图4所示，上述S101，包括：
S401，设置不同种类动物的生理信号范围，建立生理信号数据库。
在一些实施例中，通过生理信号对动物种类进行识别。首先建立生理信号数据库，例如生理信号数据库中包括小鼠、大鼠、兔子三种动物，小鼠的生理信号范围设置为：体温37-39℃，心跳频率470-780次/分钟，体重15-25克；大鼠的生理信号范围设置为：体温37.8-38.8℃，心率260-450次/分钟，180-500克的体重；兔子的生理信号范围设置为：体温38.5-39.5℃，心率180-250次/分钟，体重500-2000克。
S402，在生理信号数据库中匹配生理信号对应的动物种类，得到待扫描动物的种类。
在一些实施例中，生理信号数据库建立后，获取待扫描动物的生理信号，在生理信号数据库中进行匹配，匹配出待扫描动物的各项生理信号均在相应生理信号范围之类的动物种类，得到待扫描动物的种类。如果与待扫描动物相匹配(各项生理信号均在相应生理信号范围之类)的动物种类不止一种，则选取匹配度最高的动物种类作为最终的待扫描动物的种类。匹配度的可以采用如下公式计算：
Figure PCTCN2021117615-appb-000001
其中，P j为待扫描动物与第j个动物种类的匹配度，x i为待扫描动物第i项生理信号的值，
Figure PCTCN2021117615-appb-000002
第j个动物种类第i项生理信号的生理信号平均值，
Figure PCTCN2021117615-appb-000003
取相应生理信号范围的上限值与下限值的平均值即可。
如果与待扫描动物相匹配的动物种类为零，则选择与待扫描动物的生理信号相匹配的 项数最多的动物种类，作为最终的待扫描动物的种类。如果生理信号相匹配的项数最多的动物种类有多种，则选取匹配度最高的动物种类作为最终的待扫描动物的种类；匹配度的计算方法参照上式计算即可。
本实施例中，采用生理信号比对的方式实现动物种类的识别，生理信号的比对不需要在动物身体上设置标记，在动物身体上设置手环或脚环之类的测量装置即可，能够实现无创识别。
在一些实施例中，如图5所示，上述S101，包括：
S501，通过识别图像得到动物的体长参数。
在一些实施例中，扫描设备通过识别待扫描动物的图像，从而获得动物的体长参数，即动物从头部至尾部的长度。
在本发明的一个实施例中，通过位于动物舱的摄像头对待扫描动物进行拍摄以获取动物的图片，该图片为待扫描动物的静态图像，在识别出图片后，根据图片获取动物的体长参数，并将体长参数传输至服务器或云端等具备运算逻辑的终端设备内。
本发明的一个实施例中，识别图片得到动物体长参数的方法为，在动物的两侧设置带有刻度的标尺，以在形成图片后，直接通过识别标尺上的刻度来得到体长参数。还可以是预先在动物的身上标记特征点，如在动物的头部设置第一个特征点，然后从头部到尾部等间距地设置多个反光点，形成图片后，通过识别特征点的个数，来确定动物的体长参数。
在一个实施例中，也可以同时设置标尺及特征点，以分别识别标尺的刻度及特征点，从而验证得到体长参数的准确性。
S502，获取待扫描动物的体重参数。
具体地，本发明的一个实施例中，通过测量动物的体重，以获得动物的体重参数。
可选的，在本发明的一个实施例中，利用重力传感器对位于动物舱内的动物进行体重读取，以得到体重参数。
可选的，在本发明的另一个实施例中，扫描设备还可以通过下述方法获取待扫描动物的体重参数：
S1，获取待扫描动物的多个体重数值。
在一些实施例中，将动物放入动物舱后，其呼吸时会伴有小幅度的运动，即呼吸的过程中肺部的伸展带动身体进行轻微的运动，该轻微运动会影响重力传感器进行体重测量时的数值。在动物本身体重较轻的情况下，轻微运动所造成的测量误差会占体重较大的比重，经过多次测量，即通过人为设定一个预设时间，每个一个预设时间对动物的体重进行一次测量，可提高体重测量的准确性。在一个实施例中，预设时间的选定为根据动物的呼吸频 率进行设定。每个种类的动物呼吸频率皆不同，如猕猴的呼吸频率为30-50次/分钟，狗的呼吸频率为16-20次/分钟，猫的呼吸频率为20-30次/分钟。不同的呼吸频率，其呼吸时产生的小幅度运动不同，也即其由于小幅度运动对单次体重测量数值的影响也不同。针对不同呼吸频率的动物，设置的预设时间也不同，如对于呼吸频率高的，则减小预设时间间隔，而对于呼吸频率低的，则增大预设时间间隔。在一个实施例中，呼吸频率可以通过监护仪、呼吸检测仪等设备进行检测并统计。
可以理解的是，每次将动物放置于动物舱中时，并不能保证每次皆将动物放置于动物舱的正中心，在一个实施例中，选用压力传感器获取待扫描动物的体重参数，在一个实施例中选用四角薄膜压力传感器，进行每次的体重测量。通过四个位于动物四周的四角薄膜压力传感器同时对动物的体重数值测量得到，每次测量得到的动物体重数值即为四个薄膜压力传感器采集到的数值之和。利用四角薄膜压力传感器，可保证不管动物是否位于动物舱的正中心，皆可获得较为准确的单次测量结果。
S22，基于多个体重数值，得到待扫描动物的体重参数；
本发明的一个实施例中，在设定好间隔的预设时间，并多次获取到体重数值后，将多次获得体重数值进行平均值运算，等到的结果即为动物的体重参数。即，将多次获取的体重数值相加，然后除以采集次数得到的结果即为动物的体重参数。在一个实施例中，获取体重数值的次数至少为两次。
S503，将获取到的动物的体长参数及体重参数分别与预存的标准体长及标准体重进行比对，确定动物的种类信息。
在本发明的一个实施例中，预先在终端设备内预存了多种动物对应的标准体长及标准体重，在获取到动物的体长参数及体重参数后，扫描设备将获取到的体长参数及体重参数分别与多个预存的标准体长及标准体重进行比对，在多个预存的标准体长及标准体重中找到分别与获取的体长参数及体重参数相等的一组，即标准体长与体长参数相等，标准体重与体重参数一致，则该组标准体长及标准体重对应的动物种类即为动物舱中动物的种类。
本实施例中，通过识别待扫描动物的图像得到动物的体长参数和获取待扫描动物的体重参数的过程较为简单，只需要进行简单的识别即可实现，从而可以快速地将获取到的动物的体长参数及体重参数分别与预存的标准体长及标准体重进行比对，快速地确定出动物的种类信息，提高了确定动物的种类信息的效率。
在上述实施例的基础上，获取到待扫描动物的图像后，在对待扫描动物的图像进行识别时，除了获取动物的体长参数外，还可以获取动物的毛发参数，在一个实施例中，上述方法还包括：获取待扫描动物的图像后，还获取动物的毛发参数，根据动物的毛发参数、 体长参数及体重参数确定动物种类信息；毛发参数包括毛发的长度、毛发的直径、毛发的颜色中至少一种。
在本实施例中，在对待扫描动物的图像进行识别时，除了获取动物的体长参数外，还获取动物的毛发参数，其中，毛发参数包括毛发的长度、毛发的直径、毛发的颜色中至少一种。终端设备内还预存了多种动物的标准毛发，标准毛发也包括毛发的长度、毛发的直径、毛发的颜色中的至少一种，通过将标准毛发与毛发参数进行比对，以在同科不同属动物的体重参数、体长参数相似的情况下，进行辅助区分动物类型。
本实施例中，扫描设备在获取到待扫描动物的图像后，还可以获取动物的毛发参数，根据动物的毛发参数、体长参数及体重参数能够确定待扫描动物的动物种类信息，这样可以在同科不同属动物的体重参数、体长参数相似的情况下，进行辅助区分动物类型，提高确定动物种类信息的准确度。
在本申请一些实施例中，该动物扫描方法包括：在选择呼吸-心电协议时，通过待扫描动物的图像识别动物身体的指定部位是否剃毛并贴有电极片。
在一些实施例中，在选择协议进行扫描时，先判断所选协议是否与呼吸-心电有关，如有关，则先通过摄像头拍摄的待扫描动物的图像，通过肉眼直接观察待扫描动物的图像或者通过图像自动识别，识别并判断动物舱内动物的指定部位是否剃毛并贴有电极片，只有在指定部位剃毛并贴有电极片时，才执行呼吸-心电有关的协议，否则先执行剃毛并贴电极片的操作。如所选协议与呼吸-心电无关，则可直接执行扫描。
本实施例中，在选择呼吸-心电协议时，扫描设备通过待扫描动物的图像识别动物身体的指定部位是否剃毛并贴有电极片，能够确保扫描设备在执行扫描协议过程中的安全性，确保扫描的顺利进行。
在上述扫描设备识别待扫描动物所在动物舱的类型，判断待扫描动物的种类与动物舱的类型是否匹配的场景中，在一个实施例中，上述S102，包括：动物舱的类型包括所对应的动物床位种类以及动物床位数量；获取动物舱内各动物床位的占用情况；对处于占用状态的动物床位上的待扫描动物进行种类识别；判断待扫描动物的种类与动物床位种类是否相同，如果是，则待扫描动物的种类与动物舱的类型匹配，否则不匹配。
具体地，在本实施例中，动物舱包括不同种类动物的动物舱，例如：小鼠鼠舱、大鼠鼠舱、兔子舱。且一个动物舱内可能包括多个动物床位，例如：单只小鼠鼠舱、两只小鼠鼠舱、四只小鼠鼠舱、单只大鼠鼠舱、两只大鼠鼠舱、单只兔子舱。
本实施例在检测动物舱类型后，根据床位数量动态设置注册页面指导用户进行注册信息录入，支持录入每一个扫描对象的注册信息，以便后续扫描过程的实现。检测到动物舱 类型后，显示动物舱模型，用户选中不同的床位录入对应扫描对象的注册信息。具体的，如图6所示，工作站检测到可以同时摆放4只小鼠的动物舱(4鼠动物舱)，注册页面显示4个床位，即图3中右上角带数字“1、2、3、4”的圆形图标，用户可以点击圆形图标中相应数字，对相应床位内待扫描动物的注册信息进行录入。在注册信息录入完成后，自动对注册信息进行校验，判断是否所有必填的注册信息均已完成录入，如果否，则进行补充录入提示。可选的，扫描对象基本注册信息包括但不限于：名字、摆位、性别、年龄、体重、身长、物种、描述；注射药物的注册信息包括但不限于：药物名称、核素、剂量、注射日期、注射时间。
对于多床位的动物舱，在进行注册信息录入之前，先判断各床位的占用情况，根据床位的占用情况将床位设置为未使用状态或已使用状态。如果多床位动物舱某个或某些床位没有摆放扫描对象，可以在注册页面将床位设置为未使用。当某一床位被设置为未使用状态后，注册系统校验必填注册信息时就不会去检查未使用床位对应的扫描对象信息。
床位的占用情况的判断同样可以结合床位处相应的生理信号和/或相应的图像实现，可以参照动物存活判断方式进行判断。例如：如果生理信号不存在，且图像中没有识别到待扫描的动物，判断动物没有放入扫描区域，即床位为未使用状态；如果生理信号存在，且图像中可以识别到待扫描动物，则判断动物已经放入扫描区域且存活，即床位为已使用状态；如果生理信号不存在，但是图像中可以识别到待扫描动物，则判断动物死亡，即床位为已使用状态，但无法进行扫描，需要更换动物。
本实施例中，获取动物舱内各动物床位的占用情况较为简单，从而可以快速地对处于占用状态的动物床位上的待扫描动物进行种类识别，快速地识别出占用状态的动物床位上的待扫描动物的种类，进而可以快速地判断待扫描动物的种类与动物床位种类是否相同，快速地得到待扫描动物的种类与动物舱的类型的匹配结果，提高了得到待扫描动物的种类与动物舱的类型的匹配结果的效率。
在上述根据对应的扫描协议进行扫描，或根据用户自定义的扫描协议进行扫描之前，在一些实施例中，如图7所示，该动物扫描方法包括：
S701，获取扫描协议对应的最佳的扫描体位。
具体地，扫描设备根据扫描协议对应的扫描体位，获取上述扫描协议对应的最佳的扫描体位。可选的，扫描设备可以在扫描协议对应的多个扫描体位中，确定出该扫描协议对应的最佳的扫描体位。
S702，获取待扫描动物的图像，并识别图像中特征点作为实际特征点，结合多个实际特征点的坐标得到待扫描动物的实际体位。
具体地，本实施例中以特征点来描述其实际体位，用于描述体位的特征点的种类，可以根据待扫描动物的特点以及扫描区域的特点进行选择设置，包括描述位置的特征点和描述方向的特征点这两类特征点。例如，需要扫描小鼠的头部时，可以选择其眼睛作为特征点进行头部位置的描述，然后选择耳朵与眼睛结合起来进行头部方向的描述，这样就可以对小鼠头部的位置和方向进行全面的定位，准确描述小鼠头部的体位。其中，扫描协议对应的扫描体位包括与多个上述实际特征点一一对应的扫描特征点。
S703，计算各实际特征点与相应的扫描特征点之间的距离之和，作为距离相似度。
需要说明的是，在本发明的实施例中，计算距离相似度时，不计算所有特征点的距离之和，而是计算描述位置的特征点的距离之和，这样不仅减少计算量，也摒除描述方向的特征点对于距离相似度计算的不必要影响。
S704，连接任意两个实际特征点，得到多条实际特征线，连接任意两个扫描特征点，得到多条扫描特征线。
S705，计算各实际特征线与对应的扫描特征线之间的角度之和，作为角度相似度。
需要说明的是，在计算角度相似度时，连接构造用于描述方向的实际特征线和扫描特征线，然后仅计算描述方向实际特征线与对应的扫描特征线之间的角度之和，作为角度相似度，从而快速而准确的计算出角度相似度。
S706，计算距离相似度与角度相似度的加权和，得到实际体位与扫描体位之间的相似度。
具体地，本实施例在计算描述实际体位与扫描体位之间的相似度时，考虑了位置(包括距离)和方向(包括角度)两个方面的影响，使得计算得到的相似度可以从两个方面描述实际体位和扫描体位之间的差距。本实施例保证了实际体位和扫描体位在这两个方面均达到合格的相似度后，再进行扫描。
例如，需要扫描小鼠的头部时，可以选择其两只眼睛的特征点之间的距离之和作为距离相似度，然后选择尾巴与身体交点与两只眼睛的连线作为特征线，计算两条特征线的角度之和作为角度相似度。示例性地，如图8所示，图8中实线所示为小鼠的扫描体位、虚线所示为小鼠的实际体位。点A1、A2、A3均为扫描特征点，A1、A2为小鼠的眼睛，A3为小鼠尾巴与身体的交点。点B1、B2、B3均为实际特征点，B1、B2为小鼠的眼睛，B3为小鼠尾巴与身体的交点。计算扫描特征点A1与实际特征点B1之间的距离AB1，计算扫描特征点A2与实际特征点B2之间的距离AB2，以AB1+AB2作为距离相似度。连接A1与A3得到第一条扫描特征线，连接A2与A3得到第二条扫描特征线；连接B1与B3得到第一条实际特征线，连接B2与B3得到第二条实际特征线。计算第一条扫描特征线与 第一条实际特征线之间的角度值，计算第二条扫描特征先与第二条实际特征线之间的角度值，以两个角度值的和作为角度相似度。
可选的，距离权重和角度权重设置，可以根据待扫描动物的种类以及扫描区域对于位置和方向的要求程度高低进行设置即可，距离权重与角度权重之和为1。
S707，判断相似度是否大于设定阈值，如果否，则输出体位调整参数用于指导体位调整，直至实际体位与扫描体位之间的相似度大于设定阈值时再进行扫描。
具体地，计算距离相似度与角度相似度的加权和得到相似度后，将其与设定阈值进行比较，设定阈值根据具体需求进行设定即可，本实施例中设置为1。其中，输出体位调整参数用于指导体位调整，包括：以各实际特征点与相应扫描特征点之间的距离、各实际特征线与相应扫描特征线之间的角度，作为体位调整参数进行输出。
具体的，在输出体位调整参数时，不需要输出所有的距离参数和所有的角度参数。可以仅输出描述位置的特征点之间的距离，以及描述方向的特征线之间的角度，作为体位调整参数。在根据体位调整参数进行动物的体位调整时，可以通过人工的方式进行调整，优选通过自动方式进行调整。例如，设置包括调整机构的动物床位，通过固定组件将动物固定在床位上后，根据体位调整参数校正调整机构的参数，自动调整动物体位。调整机构包括旋转机构和平移机构，旋转机构连接相应的固定组件，用于驱动相应的固定组件旋转，以调整待扫描动物的扫描区域的摆位方向，平移机构连接相应的固定组件，用于驱动相应的固定组件移动，以调整待扫描动物的扫描区域的摆位位置。
本实施例中，在计算描述实际体位与扫描体位之间的相似度时，考虑了位置(包括距离)和方向(包括角度)两个方面的影响，使得计算得到的相似度可以从两个方面描述实际体位和扫描体位之间的差距，进而可以判断该相似度是否大于设定阈值，在相似度小于设定阈值的情况下，输出体位调整参数指导体位调整，直至实际体位与扫描体位之间的相似度大于设定阈值时再进行扫描，保证了实际体位和扫描体位在这两个方面均达到合格的相似度后，再进行扫描。
在本申请一些实施例中，动物舱上和/或动物成像设备本体上设置有摄像头。通过摄像头，获取待扫描动物的图像。摄像头可以设置在动物舱上，也可以设置在动物成像设备本体上，也可以同时设置在动物舱上和动物成像设备本体上。可以理解的是，摄像头设置在动物舱上包括设置在动物舱内部或者外表面，只要依附于动物舱结构即可，能够获取到动物舱内的待扫描动物的图像。摄像头设置在动物成像设备本体上，可以是在动物成像设备本体的外表面，也可以是在动物成像设备本体的扫描孔内。当然，摄像头可以设置多个，多个摄像头分布在动物舱上和/或动物成像设备本体上。获取待扫描动物的图像，需要对摄 像头进行对焦，在摄像头对焦的情况下获取待扫描动物的图像。在一个实施例中，如图9所示，动物成像设备本体4上设置有摄像头1，该摄像头1可以为监控摄像头，该动物扫描方法包括：获取动物舱2与摄像头1的距离，根据距离调节摄像头1的焦距，以实现摄像头的对焦。
可以理解的是，在动物成像设备进行工作时，为了方便实验人员观测动物状态，动物成像设备上集成有监控装置，即本发明实施例中的摄像头，摄像头用于对进行实验的动物进行实时观测，摄像头设置于动物成像设备本体上，动物舱初始位置位于动物成像设备之外，并可被驱动推入动物成像设备本体内，以使动物成像设备对置于动物舱上的动物进行扫描。在摄像头对动物进行监控时，为了保证监控视频的清晰度，需要摄像头具有合适的焦距，进而才能获取合适的图像。基于光学原理，摄像头的焦距与摄像头与待拍摄物体的距离以及摄像头的像距有关，在本申请一个实施例中，通过获取摄像头与动物舱之间的距离，来对摄像头的焦距进行实时调整。其中，摄像头为可变焦光学摄像头。具体地，扫描设备获取动物舱与摄像头的距离，根据动物舱与摄像头的距离调节摄像头的焦距，实现摄像头的对焦。
在一个实施例中，扫描设备获取动物舱与摄像头的距离可以通过如下步骤获取：
步骤A，获取动物舱与摄像头的初始距离。
步骤B，获取动物舱驱动装置上的编码器的实时数据，根据编码器的实时数据得到动物舱的实时行程；其中，动物舱驱动装置用于驱动动物舱运动。
步骤C，根据初始距离以及实时行程计算出动物舱与摄像头的实时距离。
在一些实施例中，在进行动物成像实验后，动物舱进行复位处理(将动物舱的位置回复至初始位置)，动物舱在进行动物成像实验前的初始位置是预先设定好的位置，摄像头的位置是固定的，动物舱与摄像头的初始距离是一定的，可直接通过安装时的安装参数获取，简单方便。本实施例中，当需要进行动物扫描时，动物舱缓慢靠近动物成像设备本体，此时，动物舱的实时行程即为动物舱从初始位置开始的行进距离，其中，动物舱由驱动装置驱动，在驱动装置上安装有编码器，编码器的数据即反应了驱动装置的运动数据，而驱动装置的运动数据与动物舱的行程实时对应。
在本发明一个实施例中，可选的，动物舱的实时行程的获取方法为：
获取动物舱驱动装置上的编码器的实时数据，根据编码器的实时数据得到动物舱的行程；其中，动物舱驱动装置用于驱动动物舱运动。可选的，本实施例中，驱动装置为电机。
在本发明一个实施例中，当动物舱与摄像头的初始距离以及动物舱的实时行程确定后，根据运动学原理，即可计算出动物舱与摄像头的实时距离，具体的，动物舱与摄像头 的实时距离的计算方法为：计算出动物舱与摄像头的初始距离和动物舱的实时行程的差值，将差值作为动物舱与摄像头的实时距离。
本实施例中，动物舱的运动为靠近摄像头的运动，故动物舱与摄像头之间的实时距离为初始距离减去实时行程之后的值。当然，在其它的实施例中，摄像头可设置于动物舱远离动物成像设备本体的一侧，此时，摄像头与动物舱的实时距离则为初始距离与实时行程的和值，故实时距离的具体计算方法根据摄像头的位置而定，本发明对此不做限定，但是应当理解的是，无论摄像头的位置设置在何处，实时距离的计算方法都应与动物舱与摄像头的初始距离以及动物舱的实时行程相关。
进一步地，得到动物舱与摄像头的实时距离后，可以根据实时距离和摄像头的像距计算出摄像头的目标焦距，根据目标焦距调节摄像头的实时焦距，以实现摄像头的对焦，具体地，摄像头的像距为固定参数，摄像头的物距随着动物舱的实时行程变化而变化，且呈线性关系，通过上述获取的动物舱的实时行程可直接计算出摄像头的物距，在得到了物距后即可根据透镜成像公式计算出焦距。需要说明的是，本实施例中，实时距离为摄像头的成像点与动物舱的某一固定点的距离，优选的实施例中，为方便测量，固定点为动物舱的前端，当然，在其它的实施例中，固定点还可选用动物舱的后端或中间某一点。示例性地，本发明一个具体实施例中，将动物舱的前进方向的前端与摄像头的距离记做l 0，将动物舱的行程记做d，则动物舱前端与摄像头的成像点的实时距离为l 0-d。故请一并参阅图10，其为摄像头透镜成像的一较佳实施例的物理模型图，由图8可知，将摄像头的像距记做i，则摄像头的物距为o＝l 0-d-i，故根据透镜成像公式：
Figure PCTCN2021117615-appb-000004
得到摄像头的目标焦距的计算方法具体为：
Figure PCTCN2021117615-appb-000005
其中，f表示摄像头的目标焦距，i表示摄像头的像距，o表示摄像头的物距。故在进行动物扫描实验时，只需实时监控动物舱的行程，即可根据上述公式快速计算出摄像头的目标焦距，简单方便。进而，由于摄像头为可变焦光学摄像头，故只需按照目标焦距进行变焦，即可保证摄像头能够拍摄到清晰的图像，无需额外测距，系统简单而且精准。
本实施例中，通过获取动物舱与摄像头的距离，能够根据动物舱与摄像头的距离调节摄像头的焦距，从而可以实现摄像头的对焦，在摄像头对焦的情况能够确保摄像头拍摄到清晰的图像。
另外，还需要说明的是，基于上述动物成像设备的监控摄像头对焦方法，还可以采用 该监控摄像头对待扫描动物进行实时监控，以便工作人员实时获取动物舱上的动物的情况。
应该理解的是，虽然图2-7的流程图中的各个步骤按照箭头的指示依次显示，但是这些步骤并不是必然按照箭头指示的顺序依次执行。除非本文中有明确的说明，这些步骤的执行并没有严格的顺序限制，这些步骤可以以其它的顺序执行。而且，图2-7中的至少一部分步骤可以包括多个步骤或者多个阶段，这些步骤或者阶段并不必然是在同一时刻执行完成，而是可以在不同的时刻执行，这些步骤或者阶段的执行顺序也不必然是依次进行，而是可以与其它步骤或者其它步骤中的步骤或者阶段的至少一部分轮流或者交替地执行。
在一个实施例中，如图11所示，提供了一种动物扫描装置，包括：第一获取单元、判断单元、匹配单元和扫描单元，其中：
第一获取单元，用于获取待扫描动物的种类；
判断单元，用于识别待扫描动物所在动物舱的类型，判断待扫描动物的种类与动物舱的类型是否匹配；
匹配单元，用于如果待扫描动物的种类与动物舱的类型匹配，则根据待扫描动物的种类匹配并呈现对应的扫描协议；
扫描单元，用于根据对应的扫描协议进行扫描，或根据用户自定义的扫描协议进行扫描。
本实施例提供的动物扫描装置，可以执行上述方法实施例，其实现原理和技术效果类似，在此不再赘述。
在上述实施例的基础上，上述装置还包括：第二获取单元和第三获取单元，其中：
第二获取单元，用于获取待扫描动物的图像。
第三获取单元，用于根据待扫描动物的图像获取待扫描动物的种类，和/或，根据所述待扫描动物的图像对待扫描动物实时监控。
本实施例提供的动物扫描装置，可以执行上述方法实施例，其实现原理和技术效果类似，在此不再赘述。
在上述实施例的基础上，上述装置还包括：第一判断单元，其中：
第一判断单元，用于判断用户自定义的扫描协议是否与待扫描动物的种类匹配，若不匹配，则提示对用户自定义的扫描协议进行修改。
本实施例提供的动物扫描装置，可以执行上述方法实施例，其实现原理和技术效果类似，在此不再赘述。
在上述实施例的基础上，上述装置还包括：第二判断单元，其中：
第二判断单元，用于获取待扫描动物的生理信号以及实时图像，结合生理信号以及实时图像判断待扫描动物是否存活；若否，则输出动物样本更换提醒。
本实施例提供的动物扫描装置，可以执行上述方法实施例，其实现原理和技术效果类似，在此不再赘述。
在上述实施例的基础上，上述第一获取单元，用于设置不同种类动物的生理信号范围，建立生理信号数据库；在生理信号数据库中匹配生理信号对应的动物种类，得到待扫描动物的种类。
本实施例提供的动物扫描装置，可以执行上述方法实施例，其实现原理和技术效果类似，在此不再赘述。
在上述实施例的基础上，上述第一获取单元，用于通过识别图像得到动物的体长参数；获取待扫描动物的体重参数；将获取到的动物的体长参数及体重参数分别与预存的标准体长及标准体重进行比对，确定动物的种类信息。
本实施例提供的动物扫描装置，可以执行上述方法实施例，其实现原理和技术效果类似，在此不再赘述。
在上述实施例的基础上，上述装置还包括：第四获取单元，其中：
第四获取单元，用于获取待扫描动物的图像后，还获取动物的毛发参数，根据动物的毛发参数、体长参数及体重参数确定动物种类信息；毛发参数包括毛发的长度、毛发的直径、毛发的颜色中至少一种。
本实施例提供的动物扫描装置，可以执行上述方法实施例，其实现原理和技术效果类似，在此不再赘述。
在上述实施例的基础上，上述第一获取单元，用于在动物的两侧设置带有刻度的标尺，通过识别标尺上的刻度来得到体长参数和/或在动物的身上标记特征点，通过识别特征点确定动物的体长参数。
本实施例提供的动物扫描装置，可以执行上述方法实施例，其实现原理和技术效果类似，在此不再赘述。
在上述实施例的基础上，上述第一获取单元，用于获取待扫描动物的多个体重数值；及基于多个体重数值，得到待扫描动物的体重参数。
本实施例提供的动物扫描装置，可以执行上述方法实施例，其实现原理和技术效果类似，在此不再赘述。
在上述实施例的基础上，上述装置还包括：识别单元，其中：
识别单元，用于在选择呼吸-心电协议时，通过待扫描动物的图像识别动物身体的指定 部位是否剃毛并贴有电极片。
本实施例提供的动物扫描装置，可以执行上述方法实施例，其实现原理和技术效果类似，在此不再赘述。
在上述实施例的基础上，可选的，动物舱的类型包括所对应的动物床位种类以及动物床位数量，上述判断单元，用于获取动物舱内各动物床位的占用情况；对处于占用状态的动物床位上的待扫描动物进行种类识别；判断待扫描动物的种类与动物床位种类是否相同，如果是，则待扫描动物的种类与动物舱的类型匹配，否则不匹配。
本实施例提供的动物扫描装置，可以执行上述方法实施例，其实现原理和技术效果类似，在此不再赘述。
在上述实施例的基础上，可选的，上述装置还包括：第五获取单元、第六获取单元、第一计算单元、第七获取单元、第二计算单元、第三计算单元和第三判断单元，其中：
第五获取单元，用于获取扫描协议对应的最佳的扫描体位。
第六获取单元，用于获取待扫描动物的图像，并识别图像中特征点作为实际特征点，结合多个实际特征点的坐标得到待扫描动物的实际体位；扫描体位包括与多个实际特征点一一对应的扫描特征点。
第一计算单元，用于计算各实际特征点与相应的扫描特征点之间的距离之和，作为距离相似度。
第七获取单元，用于连接任意两个实际特征点，得到多条实际特征线，连接任意两个扫描特征点，得到多条扫描特征线。
第二计算单元，用于计算各实际特征线与对应的扫描特征线之间的角度之和，作为角度相似度。
第三计算单元，用于计算距离相似度与角度相似度的加权和，得到实际体位与扫描体位之间的相似度。
第三判断单元，用于判断相似度是否大于设定阈值，如果否，则输出体位调整参数用于指导体位调整，直至实际体位与扫描体位之间的相似度大于设定阈值时再进行扫描。
本实施例提供的动物扫描装置，可以执行上述方法实施例，其实现原理和技术效果类似，在此不再赘述。
在上述实施例的基础上，可选的，上述装置还包括：第八获取单元，其中：
第八获取单元，用于获取动物舱与摄像头的距离，根据距离调节摄像头的焦距，以实现摄像头的对焦。
本实施例提供的动物扫描装置，可以执行上述方法实施例，其实现原理和技术效果类 似，在此不再赘述。
在上述实施例的基础上，可选的，上述第八获取单元，用于获取动物舱与摄像头的初始距离；获取动物舱驱动装置上的编码器的实时数据，根据编码器的实时数据得到动物舱的实时行程；其中，动物舱驱动装置用于驱动动物舱运动；根据初始距离以及实时行程计算出动物舱与摄像头的实时距离。
本实施例提供的动物扫描装置，可以执行上述方法实施例，其实现原理和技术效果类似，在此不再赘述。
关于动物扫描装置的具体限定可以参见上文中对于动物扫描方法的限定，在此不再赘述。上述动物扫描装置中的各个模块可全部或部分通过软件、硬件及其组合来实现。上述各模块可以硬件形式内嵌于或独立于计算机设备中的处理器中，也可以以软件形式存储于计算机设备中的存储器中，以便于处理器调用执行以上各个模块对应的操作。
在一个实施例中，如图12所示，提供了一种动物扫描系统，该动物扫描系统包括上述任一实施例所描述的动物扫描装置5，还包括动物舱6、图像获取装置7、生理信号检测装置8；其中：
动物舱6，设置于床体上，用于放置待扫描动物；
图像获取装置7用于获取待扫描动物的图像；
生理信号检测装置8用于获取待扫描动物的生理信号；
动物扫描装置5用于对待扫描动物进行扫描。
在一些实施例中，动物舱中设置有扫描床位，待扫描动物可固定于扫描床位上。图像获取装置可包括上述任一实施例中的摄像头，用于拍摄待扫描动物的图像。生理信号检测装置根据需要检测的生理信号进行设置，例如需要检测动物心跳，则采用心电监护仪。动物舱上设置有数据接口用于传输图像以及生理信号至动物扫描装置。动物扫描装置接收上述各类信号，并采用本发明提供的动物扫描方法实现扫描。
本本申请一些实施例提供的动物扫描系统，可以执行上述方法实施例，其实现原理和技术效果类似，本实施例在此不再赘述。
在上述实施例的基础上，可选的，上述动物扫描系统还包括光源和动物成像设备本体，其中，
动物成像设备本体具有一扫描孔，动物舱可沿扫描孔的轴向运动，光源固定安装在动物成像设备本体上。在一个实施例中，通过摄像头的自动对焦，光源跟随摄像头转动，为摄像头拍摄动物的图像提供必要的光线。
本实施例中，动物成像设备本体可以为动物成像设备的机架。在本申请一些实施例中， 动物成像设备为用于动物扫描成像的设备，包括CT、MR、SPECT、PET及或者两种以上模态的结合的成像设备。
本实施例提供的动物扫描系统，可以执行上述方法实施例，其实现原理和技术效果类似，本实施例在此不再赘述。
在上述实施例的基础上，可选的，图像获取装置设置于动物舱上和/或设置于动物成像设备本体上。
本实施例提供的动物扫描系统，可以执行上述方法实施例，其实现原理和技术效果类似，本实施例在此不再赘述。
最后，还需要说明的是，在本文中，诸如第一和第二等之类的关系术语仅仅用来将一个实体或者操作与另一个实体或操作区分开来，而不一定要求或者暗示这些实体或操作之间存在任何这种实际的关系或者顺序。而且，术语“包括”、“包含”或者其任何其他变体意在涵盖非排他性的包含，从而使得包括一系列要素的过程、方法、物品或者设备不仅包括那些要素，而且还包括没有明确列出的其他要素，或者是还包括为这种过程、方法、物品或者设备所固有的要素。在没有更多限制的情况下，由语句“包括一个……”限定的要素，并不排除在包括所述要素的过程、方法、物品或者设备中还存在另外的相同要素。
本说明书中各个实施例采用递进的方式描述，每个实施例重点说明的都是与其他实施例的不同之处，各个实施例之间相同相似部分互相参见即可。
对所公开的实施例的上述说明，使本领域专业技术人员能够实现或使用本申请。对这些实施例的多种修改对本领域的专业技术人员来说将是显而易见的，本文中所定义的一般原理可以在不脱离本申请的精神或范围的情况下，在其它实施例中实现。因此，本申请将不会被限制于本文所示的这些实施例，而是要符合与本文所公开的原理和新颖特点相一致的最宽的范围。

Claims (18)

  1. 一种动物扫描方法，其特征在于，所述方法包括：
    获取待扫描动物的种类；
    识别待扫描动物所在动物舱的类型，判断所述待扫描动物的种类与所述动物舱的类型是否匹配；
    如果所述待扫描动物的种类与所述动物舱的类型匹配，则根据待扫描动物的种类匹配并呈现对应的扫描协议；
    根据对应的扫描协议进行扫描，或根据用户自定义的扫描协议进行扫描。
  2. 根据权利要求1所述的动物扫描方法，其特征在于，所述方法还包括：
    获取所述待扫描动物的图像；
    根据所述待扫描动物的图像获取所述待扫描动物的种类，和/或，根据所述待扫描动物的图像对所述待扫描动物实时监控。
  3. 根据权利要求1所述的动物扫描方法，其特征在于，所述根据用户自定义的扫描协议进行扫描之前，所述方法还包括：判断所述用户自定义的扫描协议是否与所述待扫描动物的种类匹配，若不匹配，则提示对所述用户自定义的扫描协议进行修改。
  4. 根据权利要求1所述的动物扫描方法，其特征在于，所述方法还包括：
    获取所述待扫描动物的生理信号以及实时图像，结合所述生理信号以及所述实时图像判断所述待扫描动物是否存活；
    若否，则输出动物样本更换提醒。
  5. 根据权利要求4所述的动物扫描方法，其特征在于，所述获取待扫描动物的种类，包括：
    设置不同种类动物的生理信号范围，建立生理信号数据库；
    在所述生理信号数据库中匹配所述生理信号对应的动物种类，得到所述待扫描动物的种类。
  6. 根据权利要求2所述的动物扫描方法，其特征在于，所述获取待扫描动物的种类，包括：
    通过识别所述图像得到动物的体长参数；
    获取待扫描动物的体重参数；
    将获取到的动物的体长参数及体重参数分别与预存的标准体长及标准体重进行比对，确定动物的种类信息。
  7. 根据权利要求6所述的动物扫描方法，其特征在于，所述方法还包括：
    获取待扫描动物的图像后，还获取动物的毛发参数，根据动物的毛发参数、体长参数及体重参数确定动物种类信息；毛发参数包括毛发的长度、毛发的直径、毛发的颜色中至少一种。
  8. 根据权利要求6所述的动物扫描方法，其特征在于，所述通过识别所述图像得到动物的体长参数包括：
    在动物的两侧设置带有刻度的标尺，通过识别标尺上的刻度来得到体长参数和/或在动物的身上标记特征点，通过识别特征点确定动物的体长参数。
  9. 根据权利要求6所述的动物扫描方法，其特征在于，所述获取待扫描动物的体重参数包括：
    获取所述待扫描动物的多个体重数值；及
    基于多个体重数值，得到所述待扫描动物的体重参数。
  10. 根据权利要求2所述的动物扫描方法，其特征在于，所述方法还包括：
    在选择呼吸-心电协议时，通过所述待扫描动物的图像识别动物身体的指定部位是否剃毛并贴有电极片。
  11. 根据权利要求1所述的动物扫描方法，其特征在于，所述识别待扫描动物所在动物舱的类型，判断所述待扫描动物的种类与所述动物舱的类型是否匹配，包括：
    所述动物舱的类型包括所对应的动物床位种类以及动物床位数量；
    获取所述动物舱内各动物床位的占用情况；
    对处于占用状态的动物床位上的待扫描动物进行种类识别；
    判断待扫描动物的种类与所述动物床位种类是否相同，如果是，则待扫描动物的种类与所述动物舱的类型匹配，否则不匹配。
  12. 根据权利要求1所述的动物扫描方法，其特征在于，所述根据对应的扫描协议进行扫描，或根据用户自定义的扫描协议进行扫描之前，所述方法还包括：
    获取所述扫描协议对应的最佳的扫描体位；
    获取待扫描动物的图像，并识别所述图像中特征点作为实际特征点，结合多个所述实际特征点的坐标得到所述待扫描动物的实际体位；所述扫描体位包括与多个所述实际特征点一一对应的扫描特征点；
    计算各所述实际特征点与相应的扫描特征点之间的距离之和，作为距离相似度；
    连接任意两个所述实际特征点，得到多条实际特征线，连接任意两个所述扫描特征点，得到多条扫描特征线；
    计算各所述实际特征线与对应的扫描特征线之间的角度之和，作为角度相似度；
    计算所述距离相似度与所述角度相似度的加权和，得到所述实际体位与所述扫描体位之间的相似度；
    判断所述相似度是否大于设定阈值，如果否，则输出体位调整参数用于指导体位调整，直至实际体位与所述扫描体位之间的相似度大于设定阈值时再进行扫描。
  13. 根据权利要求2所述的动物扫描方法，其特征在于，所述获取所述待扫描动物的图像之前，所述方法还包括：
    获取所述动物舱与摄像头的距离，根据所述距离调节所述摄像头的焦距，以实现所述摄像头的对焦。
  14. 根据权利要求13所述的动物扫描方法，其特征在于，所述获取所述动物舱与摄像头的距离，包括：
    获取所述动物舱与所述摄像头的初始距离；
    获取动物舱驱动装置上的编码器的实时数据，根据所述编码器的实时数据得到所述动物舱的实时行程；其中，所述动物舱驱动装置用于驱动所述动物舱运动；
    根据所述初始距离以及所述实时行程计算出所述动物舱与摄像头的实时距离。
  15. 一种动物扫描装置，其特征在于，包括：
    第一获取单元，用于获取待扫描动物的种类；
    判断单元，用于识别待扫描动物所在动物舱的类型，判断所述待扫描动物的种类与所述动物舱的类型是否匹配；
    匹配单元，用于如果所述待扫描动物的种类与所述动物舱的类型匹配，则根据待扫描动物的种类匹配并呈现对应的扫描协议；
    扫描单元，用于根据对应的扫描协议进行扫描，或根据用户自定义的扫描协议进行扫描。
  16. 一种动物扫描系统，其特征在于，包括如权利要求15所述的动物扫描装置，还包括动物舱、图像获取装置、生理信号检测装置；
    所述动物舱，设置于床体上，用于放置待扫描动物；
    所述图像获取装置用于获取待扫描动物的图像；
    所述生理信号检测装置用于获取待扫描动物的生理信号；
    所述动物扫描装置用于对待扫描动物进行扫描。
  17. 根据权利要求16所述的动物扫描系统，其特征在于，还包括光源和动物成像设备本体，其中，
    所述动物成像设备本体具有一扫描孔，所述动物舱可沿所述扫描孔的轴向运动，所述光源固定安装在所述动物成像设备本体上。
  18. 根据权利要求17所述的动物扫描系统，其特征在于，所述图像获取装置设置于所述动物舱上和/或设置于动物成像设备本体上。
PCT/CN2021/117615 2020-12-31 2021-09-10 动物扫描方法、装置和系统 WO2022142458A1 (zh)

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CN101808577A (zh) * 2007-05-24 2010-08-18 皇家飞利浦电子股份有限公司 小动物成像舱和床系统
US20180049695A1 (en) * 2016-08-17 2018-02-22 Melvin Hector, JR. Body Fat Index
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