WO2022139742A1 - Produit de soin de la peau renforçant la structure de la peau - Google Patents

Produit de soin de la peau renforçant la structure de la peau Download PDF

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Publication number
WO2022139742A1
WO2022139742A1 PCT/TR2021/051259 TR2021051259W WO2022139742A1 WO 2022139742 A1 WO2022139742 A1 WO 2022139742A1 TR 2021051259 W TR2021051259 W TR 2021051259W WO 2022139742 A1 WO2022139742 A1 WO 2022139742A1
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WO
WIPO (PCT)
Prior art keywords
weight
skin care
product according
care product
oil
Prior art date
Application number
PCT/TR2021/051259
Other languages
English (en)
Inventor
Caner ACAR
Gulcin Almina FIDANLIK
Original Assignee
Eczacibasi Tuketim Urunleri Sanayi Ve Ticaret Anonim Sirketi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eczacibasi Tuketim Urunleri Sanayi Ve Ticaret Anonim Sirketi filed Critical Eczacibasi Tuketim Urunleri Sanayi Ve Ticaret Anonim Sirketi
Publication of WO2022139742A1 publication Critical patent/WO2022139742A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/345—Alcohols containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/005—Preparations for sensitive skin

Definitions

  • the subject of the invention relates to a skin care product, which enables to moisturize, meet the water requirement of, regulate the flora of and thus strengthen the structure of especially the sensitive skin of the babies delivered before completing their development in the mother's womb.
  • the skin is the part of the body that protects the internal organs from the external mechanical, chemical and biological effects by separating the same from the external environment, assists with the regulation of the body temperature and water balance and is capable of self-repair by performing the production of collagen and protein.
  • Stratum corneum epidermidis layer constitutes the outermost layer of the skin in a state of permanent contact with the external environment and enables, by maintaining the water content of the skin above 10% owing to the natural moisturizing factors it contains, the preservation of the flexible and elastic structure of the skin and of the natural flora of the skin that hosts the beneficial microorganisms.
  • the waxy vernix layer which forms in the last trimester of pregnancy on the stratum corneum and contains a great number of beneficial compounds protective for the skin, including the antimicrobial compounds, is not either fully developed in the skin of the premature babies. Therefore, the skin of the premature babies is sensitive and vulnerable and prone to infection. For this reason, it is necessary to strengthen the skin of the premature babies by moisturizing, meeting the water requirement of and regulating the flora of the skin.
  • the moisturizing products with soothing action are used for providing the care for the skin of the babies.
  • such products due to the types and/or quantities of the chemical agents they contain, result in effects that are quite the contrary by irritating the skin and leading to the loss of natural moisturizing factors and water from the stratum corneum, the development of dryness and cracks in the skin and the disruption of the natural skin flora, in case they are applied to the sensitive and vulnerable skin of the premature babies.
  • the skin care products are needed, which enable to strengthen the skin structure without irritating the skin and which are suitable for application on the sensitive skin of the premature babies as well.
  • a skin care product which enables to generate the conditions ideal for the regulation of the moisture balance of the skin and the skin flora, meets the need for water, eliminates the risk for the development of infection and thus strengthens the skin structure, has been developed within the scope of the invention.
  • the skin care product achieves said functions by means of its ingredients that are compatible with the skin pH of the babies as well, are natural and/or of natural origin and do not irritate the skin and said product is suitable for use in the care of the skin of the premature babies delivered before completing their development in the mother's womb.
  • An object of the invention is to develop a skin care product, which enables to moisturize, meet the water requirement of, regulate the flora of and thus strengthen the structure of the skin of especially the premature babies delivered before completing their development in the mother's womb.
  • Another object of the invention is to develop a skin care product, which, without causing irritation, strengthens the structure of the skin of the premature babies delivered before completing their development in the mother's womb, owing its preservative ingredient that is, unlike the conventional skin care products, compatible with the pH value of the skin of the babies and is natural and/or of natural origin.
  • Another object of the invention is to develop a lotion having the features mentioned in the previous two objects of the invention.
  • the subject of the invention relates to a skin care product, which enables to moisturize, meet the water requirement of, regulate the flora of and thus strengthen the structure of especially the sensitive skin of the babies delivered before completing their development in the mother's womb.
  • the product according to the invention basically comprises an oil phase containing the oilsoluble ingredients, a water phase containing the water-soluble ingredients, and at least one active ingredient and/or active ingredient mixture providing the moisture balance of and regulating the flora of the skin.
  • the oil phase basically contains at least one type of vegetable oil and at least one surfactant, which enables the water phase to homogeneously disperse in the oil phase and has a hydrophilic-lipophilic balance (H LB) value in the range of 3-8.
  • the water phase contains water, at least one moisturizing agent, at least one pH regulating agent enabling the pH of the composition to be adjusted to a value in the range of 4-4.5 and at least one preservative agent being active at the pH values in the range of 4-4.5.
  • the skin care product according to the invention comprises, in the oil phase, 1-8% by weight at least one type of vegetable oil and 0.5-7% by weight at least one surfactant with a HLB value of 3-8; and, in the water phase, 25-36% by weight water, 3-10% by weight at least one moisturizing agent, 0.1-0.5% by weight at least one pH regulating agent enabling the pH of the composition to be adjusted to a value in the range of 4-4.5 and 1-5% by weight at least one preservative agent being active at the pH values in the range of 4-4.5.
  • composition according to the invention comprises the vegetable oil preferably at a ratio of 4-8% by weight.
  • the product according to the invention comprises at least one surfactant with a HLB value of 3-8 at a ratio of 1.5-7% by weight.
  • the product according to the invention comprises 0.1-1% by weight at least one active ingredient or active ingredient mixture.
  • the product according to the invention comprises as the vegetable oil at least one oil selected from but not limited to olive oil, sunflower oil, sweet almond oil, jojoba oil, apricot kernel oil, avocado oil, sesame oil, macadamia oil, corn oil, wheat germ oil, safflower oil, borage oil and sea buckthorn oil.
  • the product according to the invention comprises as the surfactant at least one type of nonionic surfactant with a hydrophilic-lipophilic balance (HLB) value in the range of 3-8.
  • HLB hydrophilic-lipophilic balance
  • the product according to the invention comprises as the surfactant at least one compound selected from but not limited to the compounds Polyglyceryl -2 Dipolyhydroxystearate, Polyglyceryl-3 Diisostearate, Polyglyceryl-2 Sesquiiisostearate, Polyglyceryl-3 Polyricinoleate and Glyceryl Oleate.
  • the product according to the invention comprises two surfactants wherein said surfactants are preferably Polyglyceryl-2 Dipolyhydroxystearate preferably at a ratio of 1-5% by weight and preferably Polyglyceryl-3 Diisostearate preferably at a ratio of 0.5- 2% by weight.
  • said surfactants are preferably Polyglyceryl-2 Dipolyhydroxystearate preferably at a ratio of 1-5% by weight and preferably Polyglyceryl-3 Diisostearate preferably at a ratio of 0.5- 2% by weight.
  • the preservatives were examined in terms of their effects especially on the skin of the premature babies, whether or not they are natural or of natural origin, their solubility in water, the pH values at which they exhibit activity, their odor, and whether they cause color change in the finished product.
  • the preservatives that are natural or of natural origin have high solubility in water, are active in the pH range of 4-4.5 also, are odorless or have a pleasant smell, and do not cause any undesirable color change in the finished product were determined.
  • the product according to the invention comprises as the preservative agent at least one of the compounds sodium benzoate, benzoic acid, levulinic acid, benzyl alcohol, pentylene glycol, potassium sorbate and sodium levulinate.
  • the composition according to the invention preferably comprises pentylene glycol as the preservative.
  • the product according to the invention preferably comprises at least one of an active ingredient mixture containing maltodextrin and lactobacillus ferment as the active ingredients or an active ingredient mixture containing propanediol and broomrape (orobanche rapum) extract as the active ingredients.
  • the product according to the invention comprises preferably at least one acid, preferably citric acid, as the pH regulating agent.
  • the product according to the invention preferably comprises glycerin as the moisturizing agent.
  • the product according to the invention comprises, in addition to the main ingredients, at least one emollient at a ratio of 3-25% by weight in the oil phase.
  • the composition according to the invention preferably comprises at least one emollient at a ratio of 8-25% by weight.
  • the product according to the invention comprises at least one compound preferably selected from but not limited to the compounds caprylic/capric triglyceride, coco caprylate/caprate, isopropyl myristate and isopropyl palmitate as the emollient.
  • the product according to the invention comprises two emollients, said emollients preferably being caprylic/capric triglyceride preferably at a ratio of 5-15% by weight and coco caprylate/caprate preferably at a ratio of 3-10% by weight.
  • the product according to the invention comprises, in addition to the main ingredients, at least one type of vitamin in the oil phase and/or at least one type of vitamin in the water phase, at a ratio of 0.1-3.5% by weight, preferably 0.6-3.5% by weight, based on the composition of the finished product.
  • the product according to the invention comprises as said vitamin at least one vitamin preferably selected from but not limited to vitamin E (tocopherol acetate), vitamin B3, vitamin B5 (panthenol) and vitamin B7.
  • the product according to the invention comprises two types of vitamin, i.e. preferably vitamin E preferably at a ratio of 0.1-1.5% by weight in the oil phase and preferably vitamin B5 preferably at a ratio of 0.5-2% by weight in the water phase.
  • the product according to the invention comprises, in addition to the main ingredients, at least one type of gelling and viscosity increasing agent in the oil phase, preferably at a ratio of 0.5-2% by weight, wherein said agent is preferably zinc stearate.
  • the product according to the invention comprises, in addition to the main ingredients, at least one type of agent for providing electrolytic medium and increasing stability, in the water phase, preferably at a ratio of 1-3% by weight, wherein said agent is preferably zinc sulphate heptahydrate.
  • the product according to the invention comprises 25-36% by weight water, 4-8% by weight at least one vegetable oil, 3-10% by weight at least one moisturizing agent, 1.5-7% by weight at least one surfactant with a HLB value in the range of 3-8, 1-5% by weight preservative agent, 0.1-0.5% by weight pH regulating agent, 0.1-0.5% by weight active ingredient mixture, 0.5-2% by weight viscosity increasing agent in the oil phase, 1-3% by weight stability increasing agent in the water phase, 8-25% by weight emollient in the oil phase and 0.6-3.5% by weight vitamin.
  • Said embodiment comprises 1-2% by weight sunflower oil, 1-2% by weight jojoba oil, 1-2% by weight sesame oil and 1-2% by weight olive oil as the vegetable oil, glycerin as the moisturizing agent, 1-5% by weight polyglyceryl-2- dipolyhydroxystearate and 0.5-2% by weight polyglyceryl-3-diisostearate as the surfactant with a HLB value in the range of 3-8, pentylene glycol as the preservative agent, citric acid as the pH regulating agent, mixture of propanediol and broomrape (orobanche rapum) extract as the active ingredient mixture, zinc stearate as the viscosity increasing agent, zinc sulphate heptahydrate as the stability increasing agent, 5-15% by weight caprylic/capric triglyceride and 3-10% by weight coco caprylate/caprate as the emollient, and 0.5-2% by weight vitamin B5 in the water phase and 0.1-1% by weight vitamin E in the
  • the product according to the invention comprises 25-35% by weight water, 4-8% by weight vegetable oil, 3-10% by weight at least one moisturizing agent, 1.5-7% by weight surfactant with a HLB value in the range of 3-8, 1-5% by weight preservative agent, 0.1-0.5% by weight pH regulating agent, 0.3-1% by weight active ingredient mixture, 0.5-2% by weight viscosity increasing agent in the oil phase, 1-3% by weight stability increasing agent in the water phase, 8-25% by weight emollient in the oil phase and 0.6-3.5% by weight vitamin.
  • Said embodiment comprises 1-2% by weight sunflower oil, 1-2% by weight jojoba oil, 1-2% by weight sesame oil and 1-2% by weight olive oil as the vegetable oil, glycerin as the moisturizing agent, 1-5% by weight polyglyceryl-2-dipolyhydroxystearate and 0.5-2% by weight polyglyceryl-3-diisostearate as the surfactant with a HLB value in the range of 3-8, pentylene glycol as the preservative agent, citric acid as the pH regulating agent, mixture of maltodextrin and lactobacillus ferment as the active ingredient mixture, zinc stearate as the viscosity increasing agent, zinc sulphate heptahydrate as the stability increasing agent, 5-15% by weight caprylic/capric triglyceride and 3-10% by weight coco caprylate/caprate as the emollient, and 0.5-2% by weight vitamin B5 and 0.1-1.5% by weight vitamin E as the vitamin.
  • the skin product according to the invention is preferably a lotion.
  • the invention further relates to a method for obtaining the skin product according to the invention wherein said method comprises the process steps of
  • the product developed within the scope of the invention enables the generation of the ideal conditions necessary for regulating the moisture balance and the flora of the skin, meets the water requirement, eliminates the risk for the development of infection and thus strengthens the skin structure.
  • the skin care product achieves said functions by means of its ingredients that are compatible with the skin pH of the babies as well, are natural and/or of natural origin and do not irritate the skin, and said product is suitable for use also in the care of the skin of the babies delivered before completing their development in the mother's womb.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Cosmetics (AREA)

Abstract

L'invention a pour objet un produit de soin de la peau, qui permet d'hydrater, de répondre aux besoins en eau, de réguler la flore et donc notamment de renforcer la structure de la peau sensible des bébés nés avant leur développement complet dans le ventre de la mère. Le produit, selon l'invention, comprend essentiellement une phase huileuse contenant les ingrédients oléosolubles, une phase aqueuse contenant les ingrédients hydrosolubles, et au moins un ingrédient actif et/ou un mélange d'ingrédients actifs assurant l'équilibre entre l'humidité et la flore de la peau tout en régulant cette dernière.
PCT/TR2021/051259 2020-12-21 2021-11-22 Produit de soin de la peau renforçant la structure de la peau WO2022139742A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
TR2020/21133 2020-12-21
TR2020/21133A TR202021133A1 (tr) 2020-12-21 2020-12-21 Ci̇lt yapisini güçlendi̇ren bi̇r ci̇lt bakim ürünü

Publications (1)

Publication Number Publication Date
WO2022139742A1 true WO2022139742A1 (fr) 2022-06-30

Family

ID=82160026

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/TR2021/051259 WO2022139742A1 (fr) 2020-12-21 2021-11-22 Produit de soin de la peau renforçant la structure de la peau

Country Status (2)

Country Link
TR (1) TR202021133A1 (fr)
WO (1) WO2022139742A1 (fr)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2873413A1 (fr) * 2012-07-10 2015-05-20 Shiseido Company, Ltd. Produit cosmétique d'émulsion eau-dans-huile
KR20160071921A (ko) * 2014-12-12 2016-06-22 주식회사 풀무원 하이드롤라이즈드 호호바 에스터 오일을 포함하는 수중유형 가용화 화장료 조성물
JP2020158493A (ja) * 2019-03-20 2020-10-01 ジャパンメディック株式会社 パンテノールを含有する油中水型（ｗ／ｏ型）クリーム

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2873413A1 (fr) * 2012-07-10 2015-05-20 Shiseido Company, Ltd. Produit cosmétique d'émulsion eau-dans-huile
KR20160071921A (ko) * 2014-12-12 2016-06-22 주식회사 풀무원 하이드롤라이즈드 호호바 에스터 오일을 포함하는 수중유형 가용화 화장료 조성물
JP2020158493A (ja) * 2019-03-20 2020-10-01 ジャパンメディック株式会社 パンテノールを含有する油中水型（ｗ／ｏ型）クリーム

Also Published As

Publication number Publication date
TR202021133A1 (tr) 2022-07-21

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