WO2022107946A1 - Éléments électroceutiques rechargeables sans fil pour un traitement de l'épilepsie et procédé de commande associé - Google Patents

Éléments électroceutiques rechargeables sans fil pour un traitement de l'épilepsie et procédé de commande associé Download PDF

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Publication number
WO2022107946A1
WO2022107946A1 PCT/KR2020/016555 KR2020016555W WO2022107946A1 WO 2022107946 A1 WO2022107946 A1 WO 2022107946A1 KR 2020016555 W KR2020016555 W KR 2020016555W WO 2022107946 A1 WO2022107946 A1 WO 2022107946A1
Authority
WO
WIPO (PCT)
Prior art keywords
housing
wireless charging
magnetic field
epilepsy treatment
electronic
Prior art date
Application number
PCT/KR2020/016555
Other languages
English (en)
Korean (ko)
Inventor
이현웅
Original Assignee
오션스바이오 주식회사
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 오션스바이오 주식회사 filed Critical 오션스바이오 주식회사
Priority to PCT/KR2020/016555 priority Critical patent/WO2022107946A1/fr
Publication of WO2022107946A1 publication Critical patent/WO2022107946A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A61N1/375—Constructional arrangements, e.g. casings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A61N1/378—Electrical supply
    • H—ELECTRICITY
    • H02—GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
    • H02J—CIRCUIT ARRANGEMENTS OR SYSTEMS FOR SUPPLYING OR DISTRIBUTING ELECTRIC POWER; SYSTEMS FOR STORING ELECTRIC ENERGY
    • H02J50/00—Circuit arrangements or systems for wireless supply or distribution of electric power
    • H02J50/10—Circuit arrangements or systems for wireless supply or distribution of electric power using inductive coupling

Definitions

  • the present invention relates to an electronic drug for epilepsy treatment capable of wireless charging and a method for controlling the same.
  • Electronic medicine is a compound word of electronics and pharmaceuticals, and refers to an electronic device that treats diseases by controlling electrical signals generated in the brain and nerve cells.
  • pacemakers In the early days, simple implantable medical devices such as pacemakers were the mainstay, but recently, they are evolving into electronic devices that stimulate nerve tissue to treat chronic diseases such as epilepsy, diabetes, arthritis, and high blood pressure.
  • the e-medication is embedded under the skin, and only a specific part that needs treatment is selected and stimulated, so side effects can be minimized, and in case of emergency, the drug effect can be stopped immediately.
  • the present invention has been devised to solve the problems of the prior art, and an object of the present invention is to provide an electronic medicine capable of wireless charging.
  • an object of the present invention is to prevent the components that provide electrical stimulation to nerves from being disturbed by electromagnetic waves generated by a wireless charger in the wireless charging process of an electronic drug.
  • an electronic drug for epilepsy treatment that is embedded subcutaneously to provide electrical stimulation to nerves and can be wirelessly charged, comprising: a housing comprising a metal having an electromagnetic wave shielding function and forming an appearance; an electrical stimulation generator provided inside the housing and generating electrical stimulation provided to nerves; a battery that supplies a current to the electrical stimulation generator and can be repeatedly charged; a power receiver provided inside the housing, converting a magnetic field generated by an external wireless charger into current and supplying it to the battery; and a magnetic field transmission film provided on a portion of the upper surface of the housing to face the power receiver and transmitting the magnetic field generated by the external wireless charger into the housing; A therapeutic e-medication may be provided.
  • the housing is provided as a barrier rib for isolating the power receiver, the inner shield comprising a metal having an electromagnetic wave shielding function; may further include.
  • the edge of the magnetic field transmission layer may be located above the inner space formed by the inner shield.
  • the power receiver includes a coil having both ends connected to the battery and converting a magnetic field into a current; and a base for fixing the coil, wherein the inner shield has shield through-holes through which both ends of the coil pass, and is provided in the shield through-hole, and electromagnetic waves pass through the shield through-hole to the outside of the inner shield It may further include a; auxiliary shielding member to prevent leakage into the space.
  • the EMI filtering module for filtering the noise generated by the external wireless charger may further include.
  • the EMI filtering module may be located between the electrical stimulation generator and the battery.
  • the electric stimulation generating unit is an electronic medicine for epilepsy treatment capable of wireless charging, characterized in that the operation is automatically stopped when the wireless charging starts.
  • the metal having the electromagnetic wave shielding function may include alumina ceramic (Al203) or titanium (Ti).
  • the magnetic field transmission film may include at least one of Teflon, polyurethane, and silicon (Si), acrylic resin (acrylic), nylon (Nylon).
  • the present invention has the effect of providing an electronic drug capable of wireless charging.
  • the present invention has an effect of preventing the components that provide electrical stimulation to nerves from being disturbed by electromagnetic waves generated by the wireless charger during the wireless charging process of the electronic drug.
  • FIG. 1 is a top view of an electronic drug for epilepsy treatment capable of wireless charging according to an embodiment of the present invention.
  • Figure 2 shows a state in which the upper part, which is a component of the housing of the electronic drug for epilepsy treatment capable of wireless charging, is removed.
  • 3 is a block diagram showing detailed configurations of the electronic drug for epilepsy treatment capable of wireless charging.
  • Figure 4 shows the wireless charging in the state that the wireless charging is possible for the epilepsy treatment e-medication is embedded subcutaneously.
  • 5 is a control method of the electronic drug for epilepsy treatment capable of wireless charging, and shows a flow in which the electrical stimulation generator is controlled.
  • the electronic drug 1 is embedded under the skin to provide electrical stimulation to the nerve, thereby controlling the process of electrical transmission abnormally generated in the nerve due to epilepsy.
  • the electronic drug 1 may include a housing 11 forming an exterior, and the housing 11 may include an upper part 111 and a lower part 112 .
  • the upper part 111 and the lower part 112 may be made of a metal that shields electromagnetic waves and is non-toxic to the human body, and the metal may include at least one of alumina ceramic (Al203) and titanium (Ti).
  • Al203 alumina ceramic
  • Ti titanium
  • the electronic drug 1 is provided on a portion of the upper surface of the upper part 111 of the housing, and further includes a magnetic field transmission film 12 that transmits a magnetic field generated by the external wireless charger into the housing. and specific functions and structures thereof will be described later with reference to FIG. 2 .
  • FIG. 2 shows a state in which the upper part 111 is removed from the lower part 112 , and through this, the components provided in the housing 11 can be confirmed.
  • the electronic drug 1 is provided inside the housing 11 and supplies power to the electrical stimulation generating unit 5 that generates electrical stimulation provided to the nerve, and the electrical stimulation generating unit 5 and repeatedly
  • a battery 7 provided as a rechargeable battery capable of phosphorus charging, and a power receiver 6 provided inside the housing 11 and converting a magnetic field generated by an external wireless charger into current and supplying the battery to the battery. have.
  • the power receiver 6 has both ends connected to the battery 7 and may include a coil 61 that converts a magnetic field into an electric current, and a base 62 that fixes the coil 61, and thus, outside the human body.
  • a current may be generated in the coil 61 by electromagnetic induction.
  • the magnetic field transmission film 12 may be provided with at least any one of Teflon and polyurethane on silicon (Si), acrylic resin, nylon (Nylon) that transmits a magnetic field, It may be provided in a portion of the upper part 111 of the housing 11 to face the coil 61 .
  • the electronic medicine 1 may further include an inner shield 13 provided as a partition wall for isolating the power receiver 6 inside the housing 11 , and the inner shield 13 is the housing 11 . It may be provided with the same metal as (11).
  • the inner shield 13 may be fixed to the lower part 112 or the upper part 111 of the housing 11, and may be integrally formed with the lower part 112 or the upper part 111. may be
  • the edge of the magnetic field transmission film 12 may be positioned above the inner space formed by the inner shield 13 .
  • the inner shield 13 may have a shield through hole 13a through which both ends of the coil 61 pass, and both ends of the coil 61 passing through the shield through hole 13a are connected to the battery 7 ) can be associated with
  • the electronic drug 1 is provided to fix the coil 61 to the shield through hole 13a, and electromagnetic waves are transmitted through the shield through hole 13a to the inner shield ( 13) may further include an auxiliary shielding member 9 to prevent leakage into the external space.
  • the auxiliary shielding member 9 may be made of a material that shields electromagnetic waves such as alumina ceramic (Al203) and titanium (Ti) or carbon nanotube (CNT), and a coil 61 in the manufacturing process of the electronic drug 1 may be fixed to the shield through-hole 13a after the arrangement of the shield is completed.
  • alumina ceramic Al203
  • Ti titanium
  • CNT carbon nanotube
  • the electronic medicine 1 is provided inside the housing 11, and may further include an EMI filtering module 8 for filtering noise generated by the external wireless charger.
  • the EMI filtering module is located between the battery 7 and the power receiver 6, but can be connected to the middle of the coil 61, and can remove various noises mixed in the power frequency.
  • the electronic medicine 1 may further include a PCB (P) for control, and the PCB is on the opposite side of the power receiver 6 with the battery 7 and the electrical stimulation generating unit 5 interposed therebetween. can be provided.
  • PCB PCB
  • FIG. 3 is a block diagram of the internal components of the electronic medicine 1, wherein the electronic medicine 1 includes a control unit 3 that controls the memory 4 and other components 5, 6, 7 and 8. may include more.
  • control unit 3 and the memory 4 may be provided on the PCB (P).
  • FIG 4 illustrates a process in which the electronic medicine 1 is embedded in the lower part of the skin S, and is charged by the wireless charger C in the embedded state.
  • the process of transmitting electrical stimulation to nerves may be temporarily stopped for safety, and when wireless charging is completed, electricity is again transmitted through the electrical stimulation transmission line (14) Stimuli can be transmitted.
  • Figure 5 shows a flow that is resumed after the electrical stimulation generating unit (5) is stopped.
  • the control method includes a step (S1) of determining whether wireless charging has started, a step (S2) of stopping the operation of the electrical stimulation generating unit (5) when wireless charging is started (S2), whether the wireless charging has ended
  • the determining step (S3) and, when the wireless charging is finished, may include a step (S4) of restarting the operation of the electrical stimulation generating unit (5).
  • the present invention may additionally have different effects of each of the above-described components, and derive a new effect that cannot be seen in the prior art according to the organic coupling relationship between each of the above-described components can do.

Abstract

La présente invention concerne des éléments électroceutiques rechargeables sans fil pour un traitement de l'épilepsie, les éléments électroceutiques étant intégrés sous la peau pour fournir un stimulus électrique aux nerfs et comportant : un boîtier comprenant un métal qui a une fonction de protection contre les ondes électromagnétiques et formant l'extérieur de celui-ci ; une unité de génération de stimulus électrique, qui est disposée à l'intérieur du boîtier et génère un stimulus électrique devant être fourni aux nerfs ; une batterie, qui fournit un courant à l'unité de génération de stimulus électrique et peut être chargée de manière répétée ; une unité de réception d'énergie qui est disposée à l'intérieur du boîtier et qui convertit un champ magnétique généré au moyen d'un chargeur sans fil externe en un courant pour fournir le courant à la batterie ; et un film de passage de champ magnétique qui est disposé au niveau d'une partie de la surface supérieure du boîtier pour faire face à l'unité de réception d'énergie, et qui permet au champ magnétique généré au moyen du chargeur sans fil externe de passer dans le boîtier.
PCT/KR2020/016555 2020-11-23 2020-11-23 Éléments électroceutiques rechargeables sans fil pour un traitement de l'épilepsie et procédé de commande associé WO2022107946A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/KR2020/016555 WO2022107946A1 (fr) 2020-11-23 2020-11-23 Éléments électroceutiques rechargeables sans fil pour un traitement de l'épilepsie et procédé de commande associé

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/KR2020/016555 WO2022107946A1 (fr) 2020-11-23 2020-11-23 Éléments électroceutiques rechargeables sans fil pour un traitement de l'épilepsie et procédé de commande associé

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WO2022107946A1 true WO2022107946A1 (fr) 2022-05-27

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050113888A1 (en) * 2000-06-16 2005-05-26 Medtronic, Inc. Implantable medical device & electrical stimulation device with magnetic shield
KR20140092238A (ko) * 2011-03-17 2014-07-23 브라운 유니버시티 이식가능 무선 신경 장치
KR20170046593A (ko) * 2015-10-20 2017-05-02 샌 디에고 스테이트 유니버시티 리써치 파운데이션 삽입 가능한 양방향 무선 신경 기록 및 자극의 장치 및 방법
JP2017513684A (ja) * 2014-04-25 2017-06-01 ボストン サイエンティフィック ニューロモデュレイション コーポレイション 埋込可能医療デバイスキャパシタンス負荷効果に対する電気パルス電荷補償のためのシステム及び方法
KR20180042902A (ko) * 2016-10-19 2018-04-27 현대자동차주식회사 무선 충전 장치 및 이를 포함하는 차량
KR20210059958A (ko) * 2019-11-18 2021-05-26 오션스바이오 주식회사 무선충전이 가능한 뇌전증 치료용 전자약 및 이의 제어방법

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050113888A1 (en) * 2000-06-16 2005-05-26 Medtronic, Inc. Implantable medical device & electrical stimulation device with magnetic shield
KR20140092238A (ko) * 2011-03-17 2014-07-23 브라운 유니버시티 이식가능 무선 신경 장치
JP2017513684A (ja) * 2014-04-25 2017-06-01 ボストン サイエンティフィック ニューロモデュレイション コーポレイション 埋込可能医療デバイスキャパシタンス負荷効果に対する電気パルス電荷補償のためのシステム及び方法
KR20170046593A (ko) * 2015-10-20 2017-05-02 샌 디에고 스테이트 유니버시티 리써치 파운데이션 삽입 가능한 양방향 무선 신경 기록 및 자극의 장치 및 방법
KR20180042902A (ko) * 2016-10-19 2018-04-27 현대자동차주식회사 무선 충전 장치 및 이를 포함하는 차량
KR20210059958A (ko) * 2019-11-18 2021-05-26 오션스바이오 주식회사 무선충전이 가능한 뇌전증 치료용 전자약 및 이의 제어방법

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