WO2022105586A1

WO2022105586A1 - Medical device system and ventilation treatment assistance device

Info

Publication number: WO2022105586A1
Application number: PCT/CN2021/128001
Authority: WO
Inventors: 王慧华; 潘瑞玲
Original assignee: 深圳迈瑞生物医疗电子股份有限公司
Priority date: 2020-11-17
Filing date: 2021-11-01
Publication date: 2022-05-27
Also published as: WO2022105555A1; CN116600844A; CN116685368A

Abstract

A medical device system and a ventilation treatment assistance device. The ventilation treatment assistance device comprises: a parameter acquisition apparatus, which is used for acquiring a physiological parameter and a ventilation parameter of a patient during ventilation treatment; and a processor, which is used for starting timing for the ventilation treatment of the patient under a current ventilation strategy, obtaining a ventilation treatment time according to the timing, and generating an oxygenation respiration index; and for comparing the oxygenation respiration index with an oxygenation respiration index threshold value to acquire an oxygenation respiration index comparison result, comparing the physiological parameter with a physiological parameter threshold value to acquire a physiological parameter comparison result, comparing the ventilation parameter with a ventilation parameter threshold value to acquire a ventilation parameter comparison result, and outputting a management suggestion according to the oxygenation respiration index comparison result, the physiological parameter comparison result and the ventilation parameter comparison result.

Description

A medical device system and ventilation therapy aids

technical field

The invention relates to the technical field of medical equipment, in particular to a medical equipment system and an auxiliary device for ventilation therapy.

Background technique

On the premise of ensuring the curative effect, modern respiratory therapy pays more and more attention to the refinement of patient ventilation management in order to achieve a better therapeutic effect. Clinically, the purpose of various respiratory assistance treatments (oxygen therapy, non-invasive ventilation, invasive ventilation, ECMO, etc.) is mostly to correct the patient's hypoxemia. General clinical staff will design or change the respiratory assistance treatment strategy according to the patient's pathology or disease progression.

There are various methods of respiratory assistance therapy. One of the main clinical challenges faced by doctors when applying these respiratory assistance therapy is the lack of means to judge or predict the effect of respiratory assistance therapy. If it is not timely, it will lead to clinical problems such as poor prognosis or increased risk of infection caused by patients being on the machine for too long.

SUMMARY OF THE INVENTION

According to a first aspect, an embodiment provides an auxiliary device for ventilation therapy, including:

A parameter acquisition device, used for acquiring physiological parameters and ventilation parameters of a patient in ventilation therapy;

The processor is configured to start timing the ventilation treatment under the current ventilation strategy of the patient when it is detected that the timing condition is met, obtain the ventilation treatment time according to the timing, and generate an oxygenation corresponding to the ventilation treatment time according to the physiological parameters and the ventilation parameters Respiratory index, the oxygenation respiratory index is used to evaluate the ventilation treatment effect within the corresponding ventilation treatment time; and

When it is determined that the ventilation treatment time reaches a first duration threshold, a comparison result between the oxygenation breathing index and at least one first oxygenation breathing index threshold value is obtained, and the ventilation parameter and at least one oxygenation breathing index are obtained. a first ventilation parameter comparison result of the first ventilation parameter threshold, obtaining the first physiological parameter comparison result of the physiological parameter and at least one first physiological parameter threshold;

According to the comparison result of the first oxygenation respiration index, the comparison result of the first ventilation parameter, and the comparison result of the first physiological parameter, a corresponding first treatment suggestion is output.

According to a second aspect, an embodiment provides an auxiliary device for ventilation therapy, including:

When it is detected that the evaluation conditions are met, the oxygenation respiration index is compared with the oxygenation respiration index threshold to obtain the oxygenation respiration index comparison result, and the physiological parameter is compared with the physiological parameter threshold to obtain the physiological parameter Compare the result, compare the ventilation parameter with the ventilation parameter threshold, obtain the ventilation parameter comparison result, and obtain the ventilation parameter comparison result according to the oxygenation respiration index comparison result, the physiological parameter comparison result and the ventilation parameter comparison result Output disposition recommendations.

According to a third aspect, an embodiment provides a medical device system, comprising:

Respiratory support equipment to provide ventilation therapy to patients;

The ventilation therapy aid in the first aspect or the second aspect;

A display device for displaying treatment suggestions output by the ventilation therapy aid device.

According to a fourth aspect, an embodiment provides a medical device system, comprising:

A plurality of medical devices, at least one of the plurality of medical devices has a parameter acquisition device, and the parameter acquisition device is used to obtain the physiological parameters and ventilation parameters of the patient during the ventilation treatment;

At least one medical device in the plurality of medical devices is used to start timing the ventilation treatment under the patient's current ventilation strategy when it is detected that the timing condition is met, obtain the ventilation treatment time according to the timing, and generate a ventilation treatment time according to the physiological parameter and the ventilation parameter. The oxygenation respiration index corresponding to the ventilation treatment time, the oxygenation respiration index is used to evaluate the ventilation treatment effect within the corresponding ventilation treatment time; and

In the above embodiment, the physiological parameters and the ventilation parameters are combined to generate a new parameter for comprehensively judging or presetting the effectiveness of ventilation therapy: the oxygenation breathing index. After comparing the oxygenation breathing index, physiological parameters and ventilation parameters with the corresponding thresholds, it can provide users with corresponding ventilation treatment suggestions, so as to help medical staff judge or predict the ventilation effect, and prompt medical staff to switch the ventilation treatment mode in time to shorten the time. The effect of patient on-board time and improved prognosis.

Description of drawings

1 is a schematic diagram of a medical device system according to an embodiment;

FIG. 2 is a schematic diagram of giving different treatment suggestions in different situations by an auxiliary ventilation therapy device according to an embodiment.

Detailed ways

The present invention will be further described in detail below through specific embodiments in conjunction with the accompanying drawings. Wherein similar elements in different embodiments have used associated similar element numbers. In the following embodiments, many details are described so that the present application can be better understood. However, those skilled in the art will readily recognize that some of the features may be omitted under different circumstances, or may be replaced by other elements, materials, and methods. In some cases, some operations related to the present application are not shown or described in the specification, in order to avoid the core part of the present application from being overwhelmed by excessive description, and for those skilled in the art, these are described in detail. The relevant operations are not necessary, and they can fully understand the relevant operations according to the descriptions in the specification and general technical knowledge in the field.

Additionally, the features, acts, or characteristics described in the specification may be combined in any suitable manner to form various embodiments. At the same time, the steps or actions in the method description can also be exchanged or adjusted in order in a manner obvious to those skilled in the art. Therefore, the various sequences in the specification and drawings are only for the purpose of clearly describing a certain embodiment and are not meant to be a necessary order unless otherwise stated, a certain order must be followed.

The serial numbers themselves, such as "first", "second", etc., for the components herein are only used to distinguish the described objects, and do not have any order or technical meaning. The "connection" and "connection" mentioned in this application, unless otherwise specified, include both direct and indirect connections (connections).

Please refer to the embodiment shown in FIG. 1 , a medical equipment system is provided in this embodiment, including a respiratory support device 10 , a ventilation therapy auxiliary device 20 and a display device 30 , and the respiratory support device 10 is used to provide ventilation therapy for a patient, Ventilation therapy refers to providing respiratory support for patients by means of mechanical ventilation. There may be different ventilation strategies in ventilation therapy. Correspondingly, the respiratory support device 10 may be a ventilator, an anesthesia machine, an oxygen therapy apparatus, and the like. In this application, the ventilation strategy includes at least one of a ventilation mode and a ventilation mode. The ventilation mode can be changed while maintaining the current ventilation mode, or the ventilation mode can be changed and the ventilation mode can be changed. In this application, the ventilation mode includes but Not limited to conventional (low-flow) oxygen therapy, high-flow oxygen therapy, non-invasive ventilation, invasive ventilation, high-frequency ventilation and ECMO, ventilation modes include but are not limited to continuous positive airway pressure, volume-controlled ventilation , Pressure Controlled Ventilation, Pressure Support Ventilation, Biphasic Positive Airway Pressure, Bilevel Positive Airway Pressure, Airway Pressure Release Ventilation, Pressure Modulation Volume Controlled Ventilation, Volume Support Ventilation, Synchronized Intermittent Mandatory Ventilation, Volume Guaranteed Pressure Support ventilation as well as closed-loop ventilation. The above ventilation modes and ventilation modes are common in the art, and those skilled in the art can determine the specific meanings of each ventilation mode and ventilation mode without any doubt.

The ventilation therapy aid 20 at least includes a parameter acquisition device 21 and a processor 22 .

The parameter acquisition device 21 is used to acquire the physiological parameters and ventilation parameters of the patient during the ventilation treatment process. The above-mentioned physiological parameters include but are not limited to blood oxygen saturation, heart rate, blood pressure, and end-tidal carbon dioxide. The ventilation parameters include oxygen concentration, inhalation Parameters that can be directly measured or set, such as oxygen partial pressure, airway flow rate, airway pressure, tidal volume, and respiratory rate, also include parameters obtained through certain calculations based on these parameters, such as minute ventilation (MV), etc. It should be noted that the classification of physiological parameters and ventilation parameters is only for the purpose of describing the technical solutions of the present application more concisely, and should not be construed as a limitation on the types of parameters in the present application. In other embodiments, the parameters can also be classified in other ways. For example, the parameters involved in the present application can be divided into blood oxygen pulse parameters and respiratory parameters. The blood oxygen pulse parameters include but are not limited to blood oxygen saturation, heart rate, and blood pressure. , and respiratory parameters include but are not limited to respiratory rate, end-tidal carbon dioxide, oxygen concentration, partial pressure of inspired oxygen, airway flow rate, airway pressure, tidal volume, and minute ventilation.

The parameter acquisition device 21 may include a sensor 21a for real-time or interval acquisition of physiological parameters and ventilation parameters, and the sensor 21a may include a plurality of, for example, a pressure sensor for acquiring airway pressure and a flow sensor for acquiring airway flow rate. In some embodiments, the parameter acquisition device 21 includes a communication device 21b for receiving physiological parameters and ventilation parameters, that is to say, the ventilation therapy auxiliary device 20 does not collect data itself. For example, the respiratory support device 10 can acquire the data obtained by itself. Physiological parameters and ventilation parameters are sent to the communication device 21b in real time or at intervals, and if some ventilation parameters are set by the user, the respiratory support device 10 can directly send the parameter values of the set ventilation parameters to the communication device 21b For example, the respiratory support device 10 is a ventilator, the user can set the oxygen supply concentration during the ventilation therapy, and the ventilator can send the set value of the oxygen supply concentration to the communication device 21b for the ventilation therapy auxiliary device 20 for subsequent processing. In another embodiment, the parameter acquisition device 21 may include both a sensor 21a and a communication device 21b, that is, the ventilation therapy aid 20 may collect some parameters by itself, and may also receive parameters sent from other medical devices, Wherein, the blood oxygen saturation may come from blood gas measurement, percutaneous measurement, or pulse oximeter measurement.

The processor 22 is configured to start timing the ventilation treatment under the current ventilation strategy of the patient when it is detected that the timing condition is met, and obtain the ventilation treatment time according to the timing. The timing condition may be to start ventilation therapy, for example, start timing when the respiratory support device 10 starts to work; it may also be a timing start instruction input by the user; it may also be that the patient's physiological parameters and ventilation parameters meet preconditions. For example, in high-flow nasal oxygen therapy (HFNC), the precondition can be set as PaO2/FiO2 (or SpO2/FiO2) > 150 mmHg. Among them, PaO2 is the partial pressure of oxygen in arterial blood, FiO2 is the partial pressure of inspired oxygen, and SpO2 is the blood oxygen saturation. In some cases, the precondition can be set as 200mmHg≤PaO2/FiO2 (or SpO2/FiO2)<300mmHg. Generally, in clinical treatment, if such preconditions are met, it is considered that the current transnasal high-flow oxygen therapy has a basis for evaluating the efficacy. If the patient does not currently meet the preconditions, it is considered that the efficacy of transnasal high-flow oxygen therapy cannot be performed The evaluation or evaluation result has a large error.

While obtaining the ventilation treatment time, the processor 22 also generates an oxygenation respiration index corresponding to the ventilation treatment time according to the physiological parameters and the ventilation parameters, and the oxygenation respiration index is used to evaluate the ventilation treatment effect in the corresponding ventilation treatment time. The oxygenation respiration index includes at least one of ROX index, oxygenation index (P/F), oxygen index (OI), and pulse oxygen saturation index (OSI). Among them, the calculation formula of ROX index is:

Among them, SpO2, PaO2, and SaO2 can be used interchangeably. Assuming that a patient's SpO2=100%, FiO2=60%, and RR=24/min, then the patient's ROX index is 6.9.

The calculation formula of oxygenation index is PaO2/FiO2, the calculation formula of oxygen index is: FiO2*mean airway pressure*100/PaO2; the calculation formula of pulse oxygen saturation index is: FiO2*mean airway pressure*100/SpO2.

The processor 22 is further configured to compare the oxygenation respiration index with the oxygenation respiration index threshold when it is detected that the evaluation condition is met, obtain the oxygenation respiration index comparison result, and compare the physiological parameter with the physiological parameter threshold to obtain Physiological parameter comparison results: Compare ventilation parameters with ventilation parameter thresholds to obtain ventilation parameter comparison results, and output treatment suggestions according to oxygenation breathing index comparison results, physiological parameter comparison results, and ventilation parameter comparison results. The treatment suggestion may be output to the display device 30 for display. In some embodiments, the ventilation therapy aid 20 also includes a display, which can then display the treatment recommendation. In other embodiments, the respiratory support device 10 also includes a display, and treatment recommendations are also displayed on the respiratory support device 10 .

That is to say, in this embodiment, the physiological parameter and the ventilation parameter are combined to obtain a new index: the oxygenation respiration index. According to the oxygenation breathing index, as well as physiological parameters and ventilation parameters, relevant treatment suggestions or predictions are given, which provides an effective reference for the user's subsequent operations.

The above evaluation condition may be that the processor 22 starts timing the ventilation treatment, that is, based on the start of timing, the oxygenation respiration index comparison result, the physiological parameter comparison result and the ventilation parameter comparison result are obtained in real time; the evaluation condition is also It can be that at least one of the physiological parameter and the ventilation parameter meets a preset condition and lasts for a preset period of time. For example, when the patient's blood oxygen saturation continues to be greater than 90% for one hour, the respiratory index comparison result, the physiological parameter comparison result and the ventilation start to be obtained. Parameter comparison result; or the ratio of physiological parameters and/or ventilation parameters that meet preset conditions reaches a preset ratio threshold. For example, the obtained physiological parameters include blood oxygen saturation and respiratory rate, and the obtained ventilation parameters include inhalation Oxygen concentration, when two of these three types of parameters meet the corresponding threshold, the oxygenation and breathing index comparison results, the physiological parameter comparison results and the ventilation parameter comparison results are obtained; the evaluation condition can also be that the ventilation treatment time reaches the preset time. The duration threshold, for example, if the preset duration threshold includes 2 hours and 8 hours, the oxygenation and respiratory index comparison results, the physiological parameter comparison results, and the ventilation parameter comparison results can be obtained when the ventilation treatment time reaches 2 hours, and the ventilation treatment time can be obtained. Oxygenation respiration index comparison results, physiological parameters comparison results and ventilation parameters comparison results when the time reaches 8 hours. In the following example, the ventilation method in the ventilation strategy is nasal high-flow oxygen therapy, the oxygenation respiration index is the ROX index, and the oxygenation respiration index threshold is the ROX index threshold. , the physiological parameter is blood oxygen saturation (SpO2), the physiological parameter threshold is the blood oxygen saturation threshold, the ventilation parameter is the respiration rate (RR), and the ventilation parameter threshold is the respiratory rate threshold. For other ventilation therapy modalities and other types of oxygenation respiration indices, more or less oxygenation respiration index thresholds may be included than those exemplified below, as well as more or fewer types of physiological parameter thresholds and/or Ventilation parameter thresholds.

In this embodiment, a patient is receiving high-flow nasal oxygen therapy, the flow rate of high-flow nasal oxygen therapy is set to 40-50 L/min, and FiO2 is set to 100%, when the processor 22 detects that the patient satisfies 200mmHg≤PaO2/ When the precondition of FiO2 (or SpO2/FiO2) < 300mmHg, start timing. When it is determined that the ventilation treatment time reaches the first duration threshold, the first ROX index comparison result between the ROX index and the first ROX threshold is obtained, the first duration threshold is 2 hours, and the first ROX index threshold includes the first ROX safety threshold and the first ROX threshold. A ROX risk threshold. In this embodiment, the first ROX safety threshold is set to 3.85, the first ROX risk threshold is set to 2.85, and the processor 22 also obtains the first blood oxygen saturation and the first blood oxygen saturation threshold. A blood oxygen saturation comparison result, in this embodiment, the first blood oxygen saturation threshold is set to 93%, and the processor 22 also obtains the first breathing rate comparison result between the breathing rate and the first breathing rate threshold. A respiration rate threshold includes a first respiration rate safety threshold and a first respiration rate risk threshold. In this embodiment, the first respiration rate safety threshold is set to 25 times/min, and the first respiration rate risk threshold is set to 30 times /min. Afterwards, the processor 22 outputs a corresponding first treatment suggestion according to the first ROX index comparison result, the first respiratory rate comparison result and the first blood oxygen saturation level comparison result. In this embodiment, there are several situations for the first treatment suggestion: 1. ① ROX index ≥ 3.85 or ② blood oxygen saturation ≥ 93% and respiratory rate < 25 times/min, indicating that the success rate of HFNC is high, and the first treatment suggestion can be "Continue HFNC treatment"; 2. ①ROX index <2.85 or ②Oxygen saturation <93% and respiratory rate>30 breaths/min, the default HFNC effect is not good, the first treatment suggestion can be "change ventilation strategy", After seeing the treatment suggestion, the user can observe the clinical status of the patient. If the patient is accompanied by disturbance of consciousness, malignant arrhythmia, severe shock, acute respiratory acidosis, etc., it can be recommended to switch from HFNC to invasive mechanical ventilation. If the patient does not have the above symptoms, it can be recommended to switch from HFNC to non-invasive ventilation; 3. ①2.85≤ROX index <3.85 or ②blood oxygen saturation ≥93% and respiratory rate>25 times/min, the first treatment suggestion can be: "Continue to maintain HFNC for 6h and closely monitor the condition and vital signs".

When the first treatment recommendation is "continue to maintain HFNC for 6 hours, and closely monitor the condition and vital signs", the user can follow the recommendation for re-ventilation therapy for 6 hours, that is, the second duration threshold is 8 hours, and it is determined that the ventilation therapy time reaches the first When there are two time duration thresholds, the comparison result of the second ROX index between the ROX index and the second ROX threshold is obtained. The second ROX index threshold includes the second ROX safety threshold and the second ROX risk threshold. In this embodiment, the second ROX safety threshold The threshold is set to 4.88, the second ROX risk threshold is set to 3.85, and the processor 22 also obtains the second blood oxygen saturation comparison result between the blood oxygen saturation and the second blood oxygen saturation threshold. The second oxygen saturation threshold is set to 93%, and the processor 22 also obtains a second respiratory rate comparison result between the respiratory rate and a second respiratory rate threshold, where the second respiratory rate threshold includes a second respiratory rate safety threshold and a second respiratory rate Rate risk threshold, in this embodiment, the second respiratory rate safety threshold is set to 25 times/min, and the second respiratory rate risk threshold is set to 30 times/min. After that, the processor 22 outputs a corresponding second treatment suggestion according to the second ROX index comparison result, the second respiratory rate comparison result, and the second blood oxygen saturation level comparison result. In this embodiment, there are several situations for the second treatment suggestion: 1. ① ROX index ≥ 4.88 or ② blood oxygen saturation ≥ 93% and respiratory rate < 25 times/min, indicating that the success rate of HFNC is high, and the second treatment suggestion can be is "continue HFNC treatment"; 2. ① ROX index < 3.85 or ② oxygen saturation < 93% and respiratory rate > 30 breaths/min, the preset HFNC effect is not good, and the second treatment suggestion can be "immediate intubation for some Invasive mechanical ventilation"; 3. ①3.85≤ROX index <4.88 or ②Blood oxygen saturation ≥93% and respiratory rate>25 breaths/min, the second treatment suggestion can be "continue to maintain HFNC for 12 hours, and closely monitor the condition and vital signs".

When the second treatment recommendation is "continue to maintain HFNC for 12 hours, and closely monitor the condition and vital signs", the user can follow the recommendation for re-ventilation therapy for 12 hours, that is, the third duration threshold is 20 hours, and it is determined that the ventilation therapy time reaches the first When there are three time duration thresholds, the comparison result of the third ROX index between the ROX index and the third ROX threshold is obtained. The third ROX index threshold includes the third ROX risk threshold. In this embodiment, the third ROX risk threshold is set to 4.88. The processor 22 also obtains a third blood oxygen saturation comparison result between the blood oxygen saturation and the third blood oxygen saturation threshold. In this embodiment, the third blood oxygen saturation threshold is set to 93%, and the processor 22 also Obtain the third respiratory rate comparison result between the respiratory rate and the third respiratory rate threshold. The third respiratory rate threshold includes the third respiratory rate risk threshold. In this embodiment, the third respiratory rate risk threshold is set to 25 times/min . After that, the processor 22 outputs a corresponding third treatment suggestion according to the third ROX index comparison result, the third respiratory rate comparison result, and the third blood oxygen saturation level comparison result. In this embodiment, there are several situations for the third treatment suggestion: 1. ① ROX index ≥ 4.88 or ② blood oxygen saturation ≥ 93% and respiratory rate < 25 times/min, indicating that the success rate of HFNC is high, and the third treatment suggestion can be It is "continue HFNC treatment and closely observe vital signs"; 2. ① ROX index < 4.88 or ② oxygen saturation ≥ 93% and respiration rate > 25 breaths/min, the default effect of HFNC is not good, the third treatment suggestion can be " Immediately intubate for invasive mechanical ventilation."

The settings of the above thresholds can be built in advance by the system, or set by the user before a ventilation treatment, and can also be modified during the ventilation treatment based on the operation instructions input by the user, for example, when the ventilation treatment time is at 0. When it is between 2 hours and 2 hours, the user can set the corresponding oxygenation breathing index threshold, physiological parameter threshold and ventilation parameter threshold between 2 hours and 8 hours.

In other embodiments, the oxygenation respiration index comparison result, the ventilation parameter comparison result and the physiological parameter comparison result can also be obtained in real time or at intervals, and the oxygenation respiration index comparison result for a certain period of ventilation treatment time can also be obtained. , Ventilation parameter comparison results and physiological parameters comparison results are counted, according to the statistical results of the oxygenation breathing index comparison results, the ventilation parameter comparison results and the physiological parameters comparison results, the oxygenation breathing index can be determined during the ventilation treatment time. , the intensity or frequency of fluctuations in ventilation parameters or physiological parameters, and the processor can output corresponding treatment suggestions or predictions according to the statistical results. For example, the oxygenation respiration index threshold is the first reference threshold, the ventilation parameter threshold is the second reference threshold, and the physiological parameter threshold is the third reference threshold. The oxygenation respiration index comparison results within the first duration threshold can be counted. If the number, proportion or duration of the oxygenated breathing index exceeding the first reference threshold exceeds the set threshold, it means that the intensity or frequency of the fluctuation of the oxygenation breathing index exceeds the acceptable range, and the treatment of "change ventilation strategy" can be output at this time. It is suggested that, in the same way, through the comparison between the ventilation parameters and the second reference threshold, and the comparison between the physiological parameters and the third reference threshold, it can be determined whether the intensity or frequency of fluctuations of the physiological parameters and the ventilation parameters exceeds the acceptable range. Based on this, corresponding treatment suggestions are given.

The above treatment suggestions are only examples. The treatment suggestions can include recommending to continue the current ventilation strategy, changing to a ventilation strategy with stronger respiratory support, or changing to a ventilation strategy with weaker respiratory support, or prompting the user to adjust the ventilation strategy. Adjust the parameters or use other treatment methods such as lung recruitment.

In another embodiment, the present application also provides another medical device system, the medical device includes multiple medical devices, and the multiple medical devices may include but are not limited to ventilators, anesthesia machines, oxygen therapy instruments, monitors, Central station, medical information system and medical mobile terminal. The medical information system can be, for example, a HIS, and the medical mobile terminal can be a PDA held by a medical staff, a mobile PC, a mobile phone, or the like. At least one medical device among the plurality of medical devices can collect the physiological parameters and ventilation parameters of the patient during the ventilation treatment, and the meanings of the physiological parameters and the ventilation parameters are the same as in the previous embodiment.

The difference between this embodiment and the previous embodiment is that one or more medical devices in this embodiment cooperate together to play the role of the ventilation therapy auxiliary device 20 in the previous embodiment. For example, a medical device can include a ventilator, a monitor, and a central station, the ventilator can obtain the patient's ventilation parameters and send the ventilation parameters to the central station, and the monitor can obtain the patient's physiological parameters and also send the physiological parameters to the central station, The central station can start timing the ventilation treatment under the patient's current ventilation strategy when it detects that the timing conditions are met, obtain the ventilation treatment time according to the timing, and generate an oxygenation respiration index corresponding to the ventilation treatment time according to the physiological parameters and ventilation parameters, and , when the central station still detects that the evaluation conditions are met, it compares the oxygenation respiration index with the oxygenation respiration index threshold to obtain the oxygenation respiration index comparison result, and compares the physiological parameters with the physiological parameter threshold to obtain the physiological parameters Compare the results, compare the ventilation parameters with the ventilation parameter thresholds, obtain the ventilation parameter comparison results, and output treatment suggestions according to the oxygenation respiration index comparison results, the physiological parameter comparison results, and the ventilation parameter comparison results. The processing of the physiological parameters and the ventilation parameters by the central station is basically the same as the processing of the ventilation parameters and the physiological parameters by the ventilation therapy auxiliary device 20 in the previous embodiment.

It can be seen from this that, although the ventilation therapy auxiliary device 20 is not set in the medical equipment system in this embodiment, a new index to assist in evaluating the ventilation therapy effect can be obtained according to the physiological parameters and ventilation parameters: the oxygenation respiration index, and can According to the follow-up comparison, corresponding treatment suggestions are given.

In the above embodiment, the obtained physiological parameters and ventilation parameters can be effectively used to provide users with corresponding ventilation treatment suggestions, thereby helping medical staff to judge or predict the ventilation effect, and prompting medical staff to switch ventilation treatment modes in time, so as to shorten the time for patients to be on the machine. and improved prognosis.

Those skilled in the art can understand that all or part of the functions of the various methods in the foregoing embodiments may be implemented by means of hardware or by means of computer programs. When all or part of the functions in the above embodiments are implemented by means of a computer program, the program may be stored in a computer-readable storage medium, and the storage medium may include: read-only memory, random access memory, magnetic disk, optical disk, hard disk, etc. The computer executes the program to realize the above-mentioned functions. For example, the program is stored in the memory of the device, and when the program in the memory is executed by the processor, all or part of the above functions can be realized. In addition, when all or part of the functions in the above-mentioned embodiments are realized by means of a computer program, the program can also be stored in a server, another computer, a magnetic disk, an optical disk, a flash disk or a mobile hard disk and other storage media, and saved by downloading or copying All or part of the functions in the above embodiments can be implemented when the program in the memory is executed by the processor.

The above specific examples are used to illustrate the present invention, which are only used to help understand the present invention, and are not intended to limit the present invention. For those skilled in the art to which the present invention pertains, according to the idea of the present invention, several simple deductions, modifications or substitutions can also be made.

Claims

A ventilation therapy auxiliary device, characterized in that it comprises:

A parameter acquisition device, used for acquiring physiological parameters and ventilation parameters of a patient in ventilation therapy;

The processor is configured to start timing the ventilation treatment under the current ventilation strategy of the patient when it is detected that the timing condition is met, obtain the ventilation treatment time according to the timing, and generate an oxygenation corresponding to the ventilation treatment time according to the physiological parameters and the ventilation parameters Respiratory index, the oxygenation respiratory index is used to evaluate the ventilation treatment effect within the corresponding ventilation treatment time; and

When it is determined that the ventilation treatment time reaches a first duration threshold, a comparison result between the oxygenation breathing index and at least one first oxygenation breathing index threshold value is obtained, and the ventilation parameter and at least one oxygenation breathing index are obtained. a first ventilation parameter comparison result of the first ventilation parameter threshold, obtaining the first physiological parameter comparison result of the physiological parameter and at least one first physiological parameter threshold;

According to the comparison result of the first oxygenation respiration index, the comparison result of the first ventilation parameter, and the comparison result of the first physiological parameter, a corresponding first treatment suggestion is output.
The device of claim 1, wherein the first treatment suggestion comprises at least one of the following:

changing the ventilation strategy;

Continue to ventilate the patient with the current ventilation strategy;

Continue to perform ventilation therapy on the patient with the current ventilation strategy until the ventilation therapy time reaches the second duration threshold.
The device according to claim 2, wherein the processor is further configured to: obtain the oxygenation respiration index and at least one second oxygenation respiration when the ventilation therapy time reaches a second duration threshold. The comparison result of the second oxygenation respiration index of the index threshold is obtained, the comparison result of the ventilation parameter and the second ventilation parameter of the at least one second ventilation parameter threshold is obtained, and the first comparison result between the physiological parameter and the at least one second physiological parameter threshold is obtained. Two physiological parameter comparison results, the second oxygenation respiration index comparison result, the second ventilation parameter comparison result and the second physiological parameter comparison result, and the corresponding second treatment suggestion is output.
The device of claim 3, wherein the second treatment suggestion includes at least one of the following:

changing the ventilation strategy;

Continue to ventilate the patient with the current ventilation strategy;

Continue to perform ventilation treatment on the patient with the current ventilation strategy until the ventilation treatment time reaches a third duration threshold.
The device according to claim 4, wherein the processor is further configured to: obtain the oxygenation respiration index and at least one third oxygenation respiration when the ventilation therapy time reaches a third duration threshold. The comparison result of the third oxygenation respiration index of the index threshold is obtained, the comparison result of the ventilation parameter and the third ventilation parameter of the at least one third ventilation parameter threshold is obtained, and the third ventilation parameter of the physiological parameter and the at least one third physiological parameter threshold is obtained. Three physiological parameter comparison results, the third oxygenation respiration index comparison result, the third ventilation parameter comparison result and the third physiological parameter comparison result, output the corresponding third treatment suggestion.
The device of claim 5, wherein the third treatment suggestion comprises:

Change the ventilation strategy or continue to ventilate the patient with the ventilation strategy.
The device according to any one of claims 1 to 6, wherein the oxygenation respiration index comprises at least one of ROX index, oxygenation index, oxygen index and pulse oxygen saturation index; the physiological parameter Including at least one of blood oxygen saturation, heart rate, blood pressure, end-tidal carbon dioxide; the ventilation parameters include oxygen concentration, partial pressure of inspired oxygen, airway flow rate, airway pressure, respiratory rate, tidal volume and minute ventilation at least one of them.
The device according to claim 1, wherein the ventilation strategy includes ventilation modes and/or ventilation modes, and the ventilation modes include conventional oxygen therapy, high-flow oxygen therapy, non-invasive ventilation, invasive ventilation, and high-frequency ventilation and at least one of extracorporeal membrane oxygenation, the ventilation modes include continuous positive airway pressure, volume-controlled mode ventilation, pressure-controlled mode ventilation, pressure support ventilation, biphasic positive airway pressure, bilevel positive airway pressure at least one of pressure ventilation, airway pressure release ventilation, pressure modulated volume control ventilation, volume support ventilation, synchronized intermittent mandatory ventilation, volume guaranteed pressure support ventilation, and closed loop ventilation.
A ventilation therapy auxiliary device, characterized in that it comprises:

A parameter acquisition device, used for acquiring physiological parameters and ventilation parameters of a patient in ventilation therapy;

The processor is configured to start timing the ventilation treatment under the current ventilation strategy of the patient when it is detected that the timing condition is met, obtain the ventilation treatment time according to the timing, and generate an oxygenation corresponding to the ventilation treatment time according to the physiological parameters and the ventilation parameters Respiratory index, the oxygenation respiratory index is used to evaluate the ventilation treatment effect within the corresponding ventilation treatment time; and

When it is detected that the evaluation conditions are met, the oxygenation respiration index is compared with the oxygenation respiration index threshold to obtain the oxygenation respiration index comparison result, and the physiological parameter is compared with the physiological parameter threshold to obtain the physiological parameter Compare the result, compare the ventilation parameter with the ventilation parameter threshold, obtain the ventilation parameter comparison result, and obtain the ventilation parameter comparison result according to the oxygenation respiration index comparison result, the physiological parameter comparison result and the ventilation parameter comparison result Output disposition recommendations.
The device according to claim 9, wherein the evaluation condition includes that the ventilation treatment time reaches a preset duration threshold, wherein the preset duration threshold includes a plurality of preset duration thresholds, and each of the multiple preset duration thresholds has a corresponding Oxygenation Respiratory Index Threshold, Ventilation Parameter Threshold, and Physiological Parameter Threshold; or

The evaluation condition is that the processor starts timing the start of the ventilation therapy; or

The evaluation condition is that the physiological parameter and/or the ventilation parameter meets a preset condition and lasts for a preset period of time; or

The evaluation condition is that the ratio of the physiological parameters and/or the ventilation parameters satisfying the preset condition reaches a preset ratio threshold.
A medical device system, comprising:

Respiratory support equipment to provide ventilation therapy to patients;

The ventilation therapy assisting device of any one of claims 1 to 10;

A display device for displaying treatment suggestions output by the ventilation therapy aid device.
A medical device system, comprising:

A plurality of medical devices, at least one of the plurality of medical devices has a parameter acquisition device, and the parameter acquisition device is used to obtain the physiological parameters and ventilation parameters of the patient during the ventilation treatment;

At least one medical device in the plurality of medical devices is used to start timing the ventilation treatment under the patient's current ventilation strategy when it is detected that the timing condition is met, obtain the ventilation treatment time according to the timing, and generate a ventilation treatment time according to the physiological parameter and the ventilation parameter. The oxygenation respiration index corresponding to the ventilation treatment time, the oxygenation respiration index is used to evaluate the ventilation treatment effect within the ventilation treatment time corresponding to it; and

When it is detected that the evaluation conditions are met, the oxygenation respiration index is compared with the oxygenation respiration index threshold to obtain the oxygenation respiration index comparison result, and the physiological parameter is compared with the physiological parameter threshold to obtain the physiological parameter Compare the result, compare the ventilation parameter with the ventilation parameter threshold, obtain the ventilation parameter comparison result, and obtain the ventilation parameter comparison result according to the oxygenation respiration index comparison result, the physiological parameter comparison result and the ventilation parameter comparison result Output ventilation disposition recommendations.
The system of claim 12, wherein the medical equipment system comprises at least one of a ventilator, an anesthesia machine, an oxygen therapy apparatus, a monitor, a central station, a medical information system and a medical mobile terminal.