CN116600844A

CN116600844A - Respiratory support device, monitoring device, medical device system and parameter processing method

Info

Publication number: CN116600844A
Application number: CN202180073697.3A
Authority: CN
Inventors: 陈俊; 潘瑞玲; 王慧华; 南知白
Original assignee: Shenzhen Mindray Bio Medical Electronics Co Ltd
Current assignee: Shenzhen Mindray Bio Medical Electronics Co Ltd
Priority date: 2020-11-17
Filing date: 2021-10-26
Publication date: 2023-08-15
Also published as: WO2022105555A1; WO2022105586A1; CN116685368A

Abstract

A respiratory support apparatus (100), a monitoring apparatus (500), a medical apparatus system (1000) and a parameter processing method, the method comprising: when the timing condition is detected to be met, starting timing the ventilation treatment of the patient, and obtaining ventilation treatment time according to the timing (S100); the method comprises the steps of obtaining blood oxygen parameters and respiratory parameters of a patient (S200), generating an oxygenation respiratory index corresponding to ventilation treatment time according to the blood oxygen parameters and the respiratory parameters, wherein the oxygenation respiratory index is used for evaluating ventilation treatment effect in the ventilation treatment time corresponding to the oxygenation respiratory index (S300), outputting a real-time parameter value (S400 a) or a parameter value of a historical moment of the oxygenation respiratory index after the oxygenation respiratory index is obtained through calculation, and generating a chart (S400 b) related to the oxygenation respiratory index, so that a user can acquire related information of the ventilation treatment effect more accurately and intuitively.

Description

Respiratory support device, monitoring device, medical device system and parameter processing method

Technical Field

The invention relates to the technical field of medical treatment, in particular to a medical equipment system, a parameter processing method of the medical equipment system, a respiratory support device and a monitoring device.

Background

Oxygen therapy and mechanical ventilation are often used in clinical procedures for respiratory support therapy, such as nasal high flow oxygen therapy (HFNC) is often used for the treatment of patients with acute respiratory failure, mild ARDS, etc. In the application of HFNC, although mechanical ventilation of a portion of the patient can be avoided, it is also possible to inappropriately delay the intervention of non-invasive positive pressure ventilation or mechanical ventilation therapy and deteriorate prognosis. Thus, in HFNC applications, one of the most challenging decisions is how to predict the efficacy of HFNC and when to switch to non-invasive positive airway pressure therapy or mechanical ventilation therapy, and this challenge is faced not only by nasal high flow rate oxygen therapy but also by other respiratory support therapies, thus providing healthcare personnel with information on the assessment of the effectiveness of more ventilation therapy, which is one of the problems currently to be solved or improved.

Disclosure of Invention

According to a first aspect, there is provided in one embodiment a medical device system comprising:

a parameter acquisition device for acquiring blood oxygen parameters and respiratory parameters of a patient;

the system comprises one or more processors, a timing module and a timing module, wherein the one or more processors are used for starting timing of ventilation treatment of a patient when the timing condition is detected to be met, obtaining ventilation treatment time according to the timing, generating an oxygenation respiration index corresponding to the ventilation treatment time according to the blood oxygen parameter and the respiration parameter, evaluating ventilation treatment effect in the ventilation treatment time corresponding to the oxygenation respiration index, and generating an oxygenation respiration index trend graph and/or an oxygenation respiration index trend table, wherein the oxygenation respiration index trend graph and/or the oxygenation respiration index trend table change with time according to the oxygenation respiration index and the ventilation treatment time corresponding to the oxygenation respiration index;

And the display device is used for displaying the breathing index trend chart and/or the oxygenation breathing index trend table.

According to a second aspect, there is provided in one embodiment a medical device system comprising:

the parameter acquisition device is used for acquiring blood oxygen parameters and respiratory parameters of a patient, wherein the blood oxygen parameters and the respiratory parameters comprise at least one type of parameters, and the blood oxygen parameters and the respiratory parameters are used for obtaining an oxygenation respiratory index according to a preset calculation method;

one or more processors configured to:

setting at least two types of parameters of the blood oxygen parameter and the respiratory parameter as coordinate parameters and establishing a parameter coordinate system, wherein one coordinate axis of the parameter coordinate system corresponds to one coordinate parameter; setting at least one oxygenation respiration index threshold value, and generating a reference boundary corresponding to the oxygenation respiration index threshold value in the parameter coordinate system;

when the timing condition is detected to be met, starting timing the ventilation treatment of the patient, obtaining ventilation treatment time according to the timing, generating a breathing variation trend graph of the coordinate parameter changing along with time in the parameter coordinate system according to parameter values of the coordinate parameter corresponding to a plurality of ventilation nodes in the ventilation treatment time, wherein the ventilation nodes are used for representing the duration of the ventilation treatment, and the position relation between the breathing variation trend graph and the reference boundary is used for evaluating the ventilation treatment effect in the ventilation treatment time;

And the display device is used for displaying the parameter coordinate system and the breathing variation trend graph.

According to a third aspect, there is provided in one embodiment a medical device system comprising:

the one or more processors are used for starting timing the ventilation treatment of the patient when the timing condition is detected to be met, obtaining ventilation treatment time according to the timing, generating an oxygenation respiration index corresponding to the ventilation treatment time according to the blood oxygen parameter and the respiration parameter, wherein the oxygenation respiration index is used for evaluating the ventilation treatment effect in the ventilation treatment time corresponding to the oxygenation respiration index, comparing the parameter value of the oxygenation respiration index with an oxygenation respiration index threshold value, and outputting prompt information according to the comparison result;

and the display device is used for displaying the prompt information.

According to a fourth aspect, there is provided in one embodiment a medical device system comprising:

and the one or more processors are used for timing the ventilation treatment of the patient when the timing condition is detected to be met, obtaining ventilation treatment time according to the timing, generating an oxygenation respiratory index corresponding to the ventilation treatment time according to the blood oxygen parameter and the respiratory parameter, wherein the oxygenation respiratory index is used for evaluating the ventilation treatment effect in the ventilation treatment time corresponding to the oxygenation respiratory index and outputting a real-time parameter value of the oxygenation respiratory index.

According to a fifth aspect, there is provided in one embodiment a medical device system comprising:

parameter acquisition means for acquiring a blood oxygen parameter and a respiratory parameter of a patient, each of the blood oxygen parameter and the respiratory parameter including at least one type of parameter;

and the one or more processors are used for timing the ventilation treatment of the patient when the timing condition is detected to be met, obtaining ventilation treatment time according to the timing, and generating an oxygenation respiratory index corresponding to the ventilation treatment time according to the blood oxygen parameter and the respiratory parameter, wherein the oxygenation respiratory index is used for evaluating the ventilation treatment effect in the ventilation treatment time corresponding to the oxygenation respiratory index.

According to a sixth aspect, in one embodiment there is provided a monitoring device comprising:

at least one sensor for monitoring at least one physiological parameter of the patient, the at least one physiological parameter comprising a blood oxygen parameter and a respiratory parameter;

the display device is used for displaying a monitoring interface, and part or all of the physiological parameters are displayed on the monitoring interface;

and when the processor detects that the parameter value of the oxygenation respiration index is lower than a preset lower limit value, controlling the display device to switch the monitoring interface into an oxygenation prompting interface, and displaying at least the real-time parameter value of the oxygenation respiration index and an oxygenation respiration index trend chart, wherein the oxygenation respiration index trend chart is generated by the processor according to the oxygenation respiration index in the ventilation treatment time and is used for representing the change of the oxygenation respiration index along with time.

According to a seventh aspect, there is provided in one embodiment a respiratory support apparatus comprising:

a patient interface for connecting to a respiratory system of a patient;

a respiratory assistance device for providing respiratory support power in ventilation therapy to ventilate a patient;

a display device for displaying a ventilation interface having displayed thereon some or all of the at least one physiological parameter;

and when the processor detects that the parameter value of the oxygenation respiration index is lower than a preset lower limit value, controlling the display device to switch the ventilation interface into an oxygenation prompting interface, and displaying at least the real-time parameter value of the oxygenation respiration index and an oxygenation respiration index trend chart, wherein the oxygenation respiration index trend chart is generated by the processor according to the oxygenation respiration index in the ventilation treatment time and is used for representing the change of the oxygenation respiration index along with time.

According to an eighth aspect, there is provided in one embodiment a medical device system comprising:

a respiratory support apparatus for performing ventilation therapy for a patient;

a monitoring device for monitoring vital signs of a patient;

and at least one device of the respiratory support device and the monitoring device is used for timing the ventilation treatment of the patient when the timing condition is detected to be met, obtaining ventilation treatment time according to the timing, collecting blood oxygen parameters and respiratory parameters of the patient, and generating an oxygenation respiratory index corresponding to the ventilation treatment time according to the blood oxygen parameters and the respiratory parameters, wherein the oxygenation respiratory index is used for evaluating the ventilation treatment effect in the ventilation treatment time corresponding to the oxygenation respiratory index.

According to a ninth aspect, there is provided in one embodiment a parameter processing method of a medical device system, including:

when the condition of timing is detected to be met, starting timing the ventilation treatment of the patient, and obtaining ventilation treatment time according to the timing;

obtaining blood oxygen parameters and respiratory parameters of a patient, and generating an oxygenation respiratory index corresponding to ventilation treatment time according to the blood oxygen parameters and the respiratory parameters, wherein the oxygenation respiratory index is used for evaluating ventilation treatment effect in the ventilation treatment time corresponding to the oxygenation respiratory index;

Generating and displaying an oxygenation respiration index trend chart and/or an oxygenation respiration index trend table of the oxygenation respiration index changing along with time according to the oxygenation respiration index and the corresponding ventilation treatment time.

According to a tenth aspect, there is provided in one embodiment a parameter processing method of a medical device system, including:

obtaining blood oxygen parameters and respiratory parameters of a patient, wherein the blood oxygen parameters and the respiratory parameters comprise at least one type of parameters, and the blood oxygen parameters and the respiratory parameters are used for obtaining an oxygenation respiratory index according to a preset calculation method;

generating and displaying a breathing change trend graph of the coordinate parameters along with time change in the parameter coordinate system according to the parameter values of the coordinate parameters corresponding to the plurality of breathing nodes in the breathing treatment time, wherein the breathing nodes are used for representing the duration of the breathing treatment, and the position relationship between the breathing change trend graph and the reference boundary is used for evaluating the breathing treatment effect in the breathing treatment time.

According to an eleventh aspect, there is provided in one embodiment a parameter processing method of a medical device system, including:

and comparing the parameter value of the oxygenation respiration index with an oxygenation respiration index threshold value, and outputting prompt information according to a comparison result.

According to a twelfth aspect, there is provided in one embodiment a parameter processing method of a medical device system, including:

Outputting the real-time parameter value of the oxygenation respiration index.

According to a thirteenth aspect, there is provided in one embodiment a parameter processing method of a medical device system, including:

and obtaining blood oxygen parameters and respiratory parameters of the patient, and generating an oxygenation respiratory index corresponding to the ventilation treatment time according to the blood oxygen parameters and the respiratory parameters, wherein the oxygenation respiratory index is used for evaluating the ventilation treatment effect in the ventilation treatment time corresponding to the oxygenation respiratory index.

According to a fourteenth aspect, there is provided in one embodiment a computer readable storage medium having stored thereon a program executable by a processor to implement the methods of the ninth to thirteenth aspects described above.

In the above embodiment, the oxygenation respiratory index may be obtained by calculation, the history of the oxygenation respiratory index or the real-time parameter value may be displayed, the oxygenation respiratory index trend chart and/or the trend table may be generated according to the oxygenation respiratory index, the corresponding respiratory variation trend chart may be generated, and the parameter value of the oxygenation respiratory index may be compared with the set threshold value to obtain the corresponding prompt information. By the means, more and more visual information on the ventilation treatment effect can be provided for the user, so that the user can be assisted in evaluating the ventilation treatment effect or deciding on the next operation or diagnosis.

Drawings

FIG. 1 is a schematic diagram of a respiratory support apparatus of one embodiment;

FIG. 2 is a schematic illustration of an oxygenation hint interface of an embodiment;

FIG. 3 is a schematic illustration of an oxygenation hint interface of another embodiment;

FIG. 4 is a schematic illustration of an oxygenation hint interface of yet another embodiment;

FIG. 5 is a schematic illustration of an oxygenation hint interface of yet another embodiment;

FIG. 6 is a graph of respiratory variation trend for one embodiment;

FIG. 7 is a graph of respiratory variation trend for ventilation treatment time up to 2 hours for one embodiment;

FIG. 8 is a graph of respiratory variation trend for ventilation treatment time up to 8 hours for one embodiment;

FIG. 9 is a graph of respiratory variation trend for ventilation treatment time up to 20 hours for one embodiment;

FIG. 10 is a graph of respiratory variation trend for another embodiment of ventilation treatment time up to 2 hours;

FIG. 11 is a graph of respiratory variation trend for another embodiment of ventilation treatment time up to 8 hours;

FIG. 12 is a graph of respiratory variation trend for another embodiment of ventilation treatment time up to 20 hours;

FIG. 13 is a graph of respiratory variation trend of another embodiment;

FIG. 14 is a schematic diagram of a threshold setting interface of an embodiment;

FIG. 15 is a schematic diagram of a threshold setting interface of another embodiment;

FIG. 16 is a schematic diagram of a threshold setting interface of another embodiment;

FIG. 17 is a schematic diagram of a threshold setting interface of yet another embodiment;

FIG. 18 is a schematic diagram of a monitoring device according to an embodiment;

FIG. 19 is a schematic view of a medical device system of an embodiment;

fig. 20 is a flowchart of a parameter processing method of the medical device system of an embodiment.

Detailed Description

The application will be described in further detail below with reference to the drawings by means of specific embodiments. Wherein like elements in different embodiments are numbered alike in association. In the following embodiments, numerous specific details are set forth in order to provide a better understanding of the present application. However, one skilled in the art will readily recognize that some of the features may be omitted, or replaced by other elements, materials, or methods in different situations. In some instances, related operations of the present application have not been shown or described in the specification in order to avoid obscuring the core portions of the present application, and may be unnecessary to persons skilled in the art from a detailed description of the related operations, which may be presented in the description and general knowledge of one skilled in the art.

Furthermore, the described features, operations, or characteristics of the description may be combined in any suitable manner in various embodiments. Also, various steps or acts in the method descriptions may be interchanged or modified in a manner apparent to those of ordinary skill in the art. Thus, the various orders in the description and drawings are for clarity of description of only certain embodiments, and are not meant to be required orders unless otherwise indicated.

The numbering of the components itself, e.g. "first", "second", etc., is used herein merely to distinguish between the described objects and does not have any sequential or technical meaning. The term "coupled" as used herein includes both direct and indirect coupling (coupling), unless otherwise indicated.

The most important idea of the application is to automatically calculate the oxygenation respiration index and to display the calculated oxygenation respiration index to the user in various ways.

Referring to fig. 1, the embodiment shown in fig. 1 provides a respiratory support apparatus 100. The respiratory support apparatus 100 is used to perform ventilation therapy for a patient, and the respiratory support apparatus 100 may include, but is not limited to, a ventilator, an anesthesia machine, an oxygen therapy apparatus, and the like, and ventilation therapy includes, but is not limited to, oxygen therapy and ventilation therapy, e.g., the respiratory support apparatus 100 may perform (transnasal) high flow rate oxygen therapy, noninvasive ventilation therapy, or invasive ventilation therapy, and the like, for the patient.

In particular, respiratory support apparatus 100 may include an air source interface 110, a breathing assistance device 120, a breathing circuit 130, a sensor 140, a memory 150, a human interaction device 160, a processor 170, and a display device 180. It should be understood that fig. 1 is merely an example of a respiratory support apparatus 100 and is not intended to limit the respiratory support apparatus 100, and that when the respiratory support apparatus 100 is a particular type of instrument, more or fewer components than shown in fig. 1 may be included, or certain components may be combined, or different components may be included. For example, when the respiratory support apparatus 100 is an oxygen therapy apparatus that provides nasal high flow rate oxygen therapy (HFNC, hereinafter, HFNC refers to nasal high flow rate oxygen therapy) to a patient, the oxygen therapy apparatus may further include a gas heating device, a gas humidifying device, and the like. The breathing circuit 130 may be a single circuit or a double circuit (as shown in fig. 1).

The gas source interface 110 is adapted to be connected to a gas source (not shown) for providing a gas. The gas can be generallyOxygen, air, and the like. In some embodiments, the gas source may be a compressed gas cylinder or a central gas supply, the gas supply being of the oxygen type O ₂ And air, etc. The gas source interface 110 may include conventional components such as pressure gauges, pressure regulators, flow meters, pressure reducing valves, and proportional control and protection devices for controlling the flow of various gases (e.g., oxygen and air), respectively. The gas input by the gas source interface 110 enters the breathing pipeline 130 and forms mixed gas with the original gas in the breathing pipeline 130.

The breathing assistance device 120 is used to power spontaneous or non-spontaneous breathing of the patient, and to maintain the airway open, i.e. to drive the gas input from the gas source interface 110 and the mixed gas in the breathing circuit 130 to the respiratory system of the patient.

In particular embodiments, breathing assistance apparatus 120 generally includes a mechanically controlled ventilation module having an airflow conduit in communication with a breathing circuit 130.

The breathing circuit 130 of the present application may be a double circuit including an inhalation path 130a and an exhalation path 130b. The mixed gas of fresh air introduced from the air source interface 110 is inputted from the inlet of the inhalation passage 130a and supplied to the patient through the patient interface 131 provided at the outlet of the inhalation passage 130 a. In other embodiments, the breathing circuit 130 may also be a single tube circuit, for example, the patient interface 131 is a mask worn on the face of the patient, the single tube circuit delivering breathing gas into the mask for inhalation by the patient, and the gas exhaled by the patient is exhausted directly through the mask or exhalation valve. Further, when the respiratory support apparatus 100 is an oxygen therapy apparatus, the patient interface may be a nasal plug for insertion into the patient's nose.

The sensor 140 is used to acquire in real time physiological parameters of the patient during ventilation therapy, the sensor 140 may include one or more physiological parameters which may include blood oxygen parameters including, but not limited to, percutaneous blood oxygen saturation (SpO 2), arterial blood oxygen partial pressure (PaO 2), and arterial blood oxygen saturation (SaO 2), and respiratory parameters which may include, but not limited to, inhalation oxygen partial pressure (FiO 2), and patient Respiratory Rate (RR). In some embodiments, the respiratory support apparatus 100 further comprises a communication apparatus 190, the communication apparatus 190 being operative to receive externally transmitted blood oxygen parameters and respiratory parameters of the patient, that is, in this embodiment, the respiratory support apparatus 100 itself does not acquire blood oxygen parameters and respiratory parameters to be processed later, but is acquired by other medical apparatuses and then sent to the respiratory support apparatus 100 for processing, while in other embodiments, the sensor 140 and the communication apparatus 190 may be combined, for example, the respiratory support apparatus 100 itself acquires respiratory parameters in real time via the sensor 140, and receives externally transmitted blood oxygen parameters via the communication apparatus 190, and then processes the respiratory parameters and the blood oxygen parameters.

The memory 150 may be used to store data or programs, such as data collected by the various sensors 140, data computationally generated by the processor 170, or image frames generated by the processor 170, which may be 2D or 3D images, or the memory 150 may store a graphical user interface, one or more default image display settings, programming instructions for the processor 170. The memory 150 may be a tangible and non-transitory computer readable medium such as flash memory, RAM, ROM, EEPROM, or the like.

The respiratory support apparatus 100 may receive input instruction signals via the human-machine interaction device 160, which may include ventilation mode control, ventilation parameter settings, etc. for the respiratory support apparatus 100. The human-machine interaction device 160 may include one or more of a keyboard, a mouse, a wheel, a mobile input device (e.g., a mobile device with a touch screen, a mobile phone, etc.), etc.

The processor 170 is configured to execute instructions or programs, control various control valves in the breathing assistance device 120, the air source interface 110, and/or the breathing circuit 130, process received data, generate required calculation or determination results, or generate visual data or graphics, and output the visual data or graphics to the display device 180 for display.

The display device 180 is configured to display a ventilation interface on which some or all of the at least one physiological parameter is displayed, the display device 180 may include one or more display screens, and each display screen may be a touch display screen or a non-touch display screen, and when the display device 180 includes a touch display screen, the touch display screen may also be a part of the human-machine interaction device 160, and receive an instruction from a user in response to a touch operation by the user.

In this embodiment, the processor 170 is configured to, upon detecting that the timing condition is met, start timing the ventilation therapy of the patient and derive a ventilation therapy time based on the timing. For example, when the user starts timing after pressing the entity or virtual key that starts timing, or when it is detected that ventilation therapy is started, in some embodiments, the processor 170 will first determine whether the patient's physiological parameters meet a precondition, and will begin calculating ventilation therapy time when the precondition is met, e.g., in transnasal high flow oxygen therapy (HFNC), the precondition may be set to PaO2/FiO2 (or SpO2/FiO 2) > 150mmHg, and in some cases, 200mmHg +.PaO 2/FiO2 (or SpO2/FiO 2) < 300mmHg. In clinical treatment, the precondition is generally satisfied, the basis for evaluating the curative effect of the nasal high-flow rate oxygen therapy is considered to be available when the nasal high-flow rate oxygen therapy is performed next time, and if the current sign parameters of the patient do not satisfy the precondition, the nasal high-flow rate oxygen therapy curative effect evaluation cannot be performed or the evaluation result is considered to have a large error.

While the ventilation therapy time is being obtained, the processor 170 also generates an oxygenated respiratory index corresponding to the ventilation therapy time based on the blood oxygen parameter and the respiratory parameter, the oxygenated respiratory index being used to evaluate the ventilation therapy effect over the corresponding ventilation therapy time. The oxygenation respiration index comprises at least one of a ROX index, an oxygenation index (P/F), an Oxygen Index (OI), and a pulse Oxygen Saturation Index (OSI). Wherein, the calculation formula of the ROX index is:

wherein SpO2, paO2, saO2 can be used instead of each other, assuming that spo2=100%, fio2=60%, rr=24/min for a patient, the ROX index for that patient is 6.9.

The formula of the oxygenation index is PaO2/FiO2, and the formula of the oxygenation index is: fiO2 mean airway pressure 100/PaO2; the calculation formula of the pulse oxygen saturation index is as follows: fiO2 mean airway pressure 100/SpO2.

The following specifically describes how the oxygenation respiration index is utilized during ventilation therapy.

In some embodiments, as shown in fig. 2-5, processor 170 generates a real-time parameter value of the oxygenation respiration index from the parameter value of the blood oxygenation parameter and the parameter value of the respiration parameter, and display device 180 may display the real-time parameter value of the oxygenation respiration index. The display of the oxygenation respiration index on the display device 180 is understood herein to be either a display of the oxygenation respiration index directly on the ventilation interface or a display of a parameter value of the oxygenation respiration index on the ventilation interface by a user operation call. In addition to acquiring parameter values of the oxygenation respiration index in real time (continuously), the processor 170 may also acquire parameter values of the oxygenation respiration index at intervals, for example, when the ventilation treatment time reaches 2 hours, 8 hours, and 20 hours, the processor 170 acquires parameter values of the oxygenation respiration index, respectively, and displays the parameter values on the display device 180. Furthermore, the parameter values of the blood oxygen parameter and the parameter values of the respiratory parameter may be displayed on the display device 180 simultaneously, and the synchronous display herein may be understood that when the parameter values of the oxygenation respiratory index are real-time, the parameter values of the blood oxygen parameter and the parameter values of the respiratory parameter are also real-time, and when the parameter values of the oxygenation respiratory index are a certain point in time (for example, 2 h), the parameter values of the blood oxygen parameter and the parameter values of the respiratory parameter are also the point in time (for example, 2 h).

In the respiratory support apparatus 100, the user may not need to manually calculate the parameter value of the oxygenation respiratory index any more, and the user may be further assisted in determining the effect of ventilation therapy by observing the parameter value of the oxygenation respiratory index generated in real time or the parameter value of the oxygenation respiratory index generated at an observation interval, especially by combining the parameter value of the synchronous blood oxygen parameter and the parameter value of the respiratory parameter.

In some embodiments, the processor 170 may also generate a trend of the oxygenation respiration index over time according to the acquired oxygenation respiration index and its corresponding ventilation treatment time, and display the trend of the oxygenation respiration index on the display device 180, which may be presented in the form of an oxygenation respiration index trend chart 310a or an oxygenation respiration index trend table 310 b. The oxygenation-respiration-index trend chart 310a may be a waveform chart, a line chart, a bar chart, a dial or other graphical display means, and reflects continuous or intermittent calculation and monitoring of the oxygenation respiration index, and the oxygenation-respiration-index trend chart 310b further reflects intermittent calculation and monitoring of the oxygenation respiration index at certain specific moments. In fig. 2-4, the oxygenation respiration index trend chart 310a is a waveform chart including trend waveforms of oxygenation respiration index with time. The processor 170 may also generate a trend of the blood oxygen parameter and a trend of the respiratory parameter, and the display device 180 may display the trend of the oxygenation respiration index, the trend of the blood oxygen parameter, and the trend of the respiratory parameter simultaneously. The trend of the change of the blood oxygen parameter can be shown in the form of a blood oxygen parameter trend chart or a blood oxygen parameter trend table, and the trend of the change of the respiratory parameter can be shown in the form of a respiratory parameter trend chart or a respiratory parameter trend table. For example, in fig. 3, a trend graph with a ROX index is shown, together with a trend graph with blood oxygen saturation and a trend graph with respiration rate. In other embodiments, the display device 180 may display only the trend of the oxygenation respiration index and the trend of the blood oxygen parameter, or only the trend of the oxygenation respiration index and the trend of the respiration parameter, or may display the trend of the oxygenation respiration index and the trend of the other physiological parameter.

In fig. 3 and 4, the oxygenation-respiration-index trend chart 310a, the blood-oxygen-parameter trend chart, and the respiration-parameter trend chart are each formed with a time line 312, and the positions of the time lines 312 in each trend chart represent the same time, whereas in fig. 3, the blood-oxygen-parameter trend chart and the respiration-parameter trend chart share one coordinate system, so that they share one time line 312. When the user moves one of the time lines 312 (e.g., drags the time line 312 with a mouse), the other time lines 312 move with it, so that the time lines 312 on each trend graph remain characteristic of the same time. Processor 170 may output the parameter values of the oxygenation respiration index, the parameter values of the blood oxygenation parameters, and the parameter values of the respiration parameters at the times indicated by time line 312, such as, for example, a parameter value of the ROX index of 4.23, a parameter value of the blood oxygenation saturation of 94%, and a parameter value of the respiration rate of 24/min at the times corresponding to time line 312 are shown in fig. 3. In addition, in the absence of the blood oxygen parameter trend graph and the respiratory parameter trend graph, the time line 312 may be displayed only on the oxygenation respiration index trend graph 310a, for example, as shown in fig. 2, in which the time line 312 may be used to select a historical parameter value of the oxygenation respiration index.

That is, the time line 312 indicates the same time portion in the three trend charts in fig. 3 as a mark in the trend chart, and the user can intuitively compare the parameter value of the oxygenation respiration index, the parameter value of the blood oxygenation parameter, and the parameter value of the respiration parameter at the same history time. In other embodiments, the trend graphs may also be labeled with other graphics, such as triangle arrows.

In addition to the above-described parameter values that are displayed by moving the time-scale line 312 to determine when to display, the user-selected historical time may be determined based on a time-selection instruction entered by the user for the oxygenation-respiration-index trend-map 310a, which may be entered by the user directly in touch with the touch-sensitive display screen, such as by a finger touching a portion of the oxygenation-respiration-index trend-map 310a on the touch-sensitive display screen, or by an external input device (keyboard, mouse, or wheel). Of course, after the above-mentioned historical time is determined, the parameter values of the blood oxygen parameter and/or the parameter values of the respiratory parameter at the same historical time may be displayed at the same time, so that the user may conveniently check the historical parameter values of the oxygenation respiratory index, the blood oxygen parameter and the respiratory parameter.

The processor 170 may divide the oxygenation respiration index trend chart 310a into at least two first areas 314 extending along the time axis with the oxygenation respiration index threshold as a boundary according to at least one oxygenation respiration index threshold, wherein the oxygenation respiration index threshold may be set as a default threshold of the system or may be input by a user operation, and the user operation input may be a touch operation directly on a touch display screen or an operation through an external input device (a keyboard, a mouse or a roller), and may evaluate the effect of ventilation therapy according to which first area 314 the trend waveform falls in the oxygenation respiration index trend chart 310 a.

The following will specifically describe the ROX index in HFNC therapy. In this embodiment, the oxygenation respiration index threshold corresponding to the ROX index includes two types, specifically, a ROX valid threshold and a ROX invalid threshold, where the ROX valid threshold is greater than the ROX invalid threshold. In other embodiments herein, the oxygenation respiration index threshold corresponding to the ROX index may be at least one of a ROX valid threshold and a ROX invalid threshold. The trend graph of the ROX index in fig. 4 is divided into three first areas 314 by a ROX effective threshold and a ROX ineffective threshold, wherein when the trend waveform of the ROX index is located in the first area 314 at the top, it means that the nasal high flow rate oxygen therapy effect is better, the HFNC can be continuously maintained, when the trend waveform of the ROX index is located in the first area 314 at the middle, it means that the nasal high flow rate oxygen therapy effect is general, the HFNC can be continuously maintained and observed for a period of time, and when the trend waveform of the ROX index is located in the first area 314 at the bottom, it means that the nasal high flow rate oxygen therapy effect is poor, the HFNC can be stopped and other more "powerful" ventilation therapy modes can be used instead.

In order to better determine which first region 314 the trend waveform of the ROX index is located in, at least two first regions 314 are marked differently on the trend chart of the ROX index, respectively, in fig. 4, the lowermost first region 314 and the uppermost first region 314 are marked differently, respectively, the middle first region 314 remains transparent, visually forms different color blocks, and in addition, each first region 314 may be filled with different patterns. In addition to the manner in which the first regions 314 are marked, a boundary line 316 between adjacent first regions 314 may also be displayed.

In addition to marking the first areas 314 in various ways, trend waveforms within different first areas 314 may be displayed in different ways, e.g., trend waveforms within each first area 314 may have corresponding colors, or may be distinguished in brightness or waveform line type in addition to colors.

As shown in fig. 5, when the trend of the change in the ROX index is shown in the form of a trend table, three threshold ranges may be determined by the ROX valid threshold and the ROX invalid threshold, each threshold range corresponding to the map of the first region 314, the parameter values of the ROX index falling within the different threshold ranges may be displayed in different manners, for example, in the trend table of the ROX index, the parameter values of the ROX index larger than the ROX valid threshold are displayed in green, and the parameter values of the ROX index smaller than the ROX invalid threshold are displayed in red.

It should be noted that the ROX valid threshold and the ROX invalid threshold herein are merely illustrative, not limiting, of the ROX index corresponding to the oxygenation respiration index threshold, and the oxygenation respiration index threshold corresponding to the ROX index may be more or less, and may also have different names, for example, the oxygenation respiration index threshold corresponding to the ROX index in fig. 2 and fig. 3 includes three, and may be defined as an ROX upper limit threshold 4.88, an ROX middle limit threshold 3.85 and an ROX lower limit threshold 2.85, respectively, and corresponding boundary lines 316 are generated according to the three thresholds on the trend graph of the ROX index.

In some embodiments, in addition to the above-described oxygenation-respiration-index trend chart 310a, the patient's respiration variability trend may be shown in another chart. Specifically, the processor 170 sets at least two types of parameters of the blood oxygen parameter and the respiratory parameter as coordinate parameters and establishes a parameter coordinate system, wherein one coordinate axis of the parameter coordinate system corresponds to one coordinate parameter, and possible types of the blood oxygen parameter and the respiratory parameter are fully described above, which is not described herein, and the oxygenation respiratory index can be calculated through the blood oxygen parameter and the respiratory parameter. How to build the parameter coordinate system and how to apply the parameter coordinate system is also described below in terms of a ROX index in HFNC, wherein the corresponding oxygenated breathing index threshold value of the ROX index may comprise at least one of a ROX valid threshold value and a ROX invalid threshold value, and the ROX valid threshold value is greater than the ROX invalid threshold value. For other ventilation therapy regimes, and other types of oxygenation respiration index, more or fewer oxygenation respiration index thresholds than the examples set forth below may be included, as well as more or fewer types of blood oxygenation parameters and respiration parameters.

It has been described above that, to obtain the ROX index, the blood oxygen parameter to be obtained is the blood oxygen saturation, and the respiratory parameter to be obtained includes two types, that is, the inhaled oxygen concentration and the respiratory rate, and based on these three types of parameters, the parameter coordinate system may be a two-dimensional parameter coordinate system or a three-dimensional parameter coordinate system, which will be described in order below.

Fig. 6 to 9 show a two-dimensional parameter coordinate system with respect to the ROX index, in which the respiration rate and the blood oxygen saturation are coordinate parameters, and in which the respiration rate corresponds to the abscissa and the blood oxygen saturation corresponds to the ordinate, and the other inhaled oxygen concentration is set as a constant parameter, which means that the parameter value of the parameter is a changeable fixed amount, for example, in fig. 6 to 9, the inhaled oxygen concentration is fixedly set to one hundred percent. At least one of an effective reference boundary 322a corresponding to the ROX effective threshold and an ineffective reference boundary 322b corresponding to the ROX ineffective threshold are generated on the two-dimensional parameter coordinate system, respectively. The meaning of the active reference boundary 322a is: if any point on the effective reference boundary 322a is taken, the abscissa and the ordinate corresponding to the point are brought into the calculation formula of the ROX index, and then the set constant parameters are set: the value of the parameter of the resulting ROX index is equal to the ROX effective threshold, and the meaning of the invalid reference boundary 322b is similar to that of the effective reference boundary 322a, so that two points can be seen: 1. the parameter value of the ROX index represented by each point on the valid reference boundary 322a is equal to the ROX valid threshold, while the parameter value of the ROX index represented by each point on the invalid reference boundary 322b is equal to the ROX invalid threshold; 2. the positions of the valid reference boundary 322a and the invalid reference boundary 322b in the two-dimensional parameter coordinate system are associated with not only the ROX valid threshold and the ROX invalid threshold, but also the parameter values of the constant parameters set in the two-dimensional parameter coordinate system. It will be readily appreciated that in other embodiments, if only two types of parameters are required to obtain the oxygenation respiration index, then no constant parameters exist for the corresponding two-dimensional parameter coordinate system.

After generating the two-dimensional parameter coordinate system, according to the parameter values of the corresponding coordinate parameters of the plurality of ventilation nodes in the ventilation treatment time, a respiration variation trend chart 320 with the time variation of the coordinate parameters is generated in the two-dimensional parameter coordinate system, and the display device 180 may display the two-dimensional parameter coordinate system and the respiration variation trend chart 320 therein, and the positional relationship between the respiration variation trend chart 320 and the effective reference boundary 322a and the ineffective reference boundary 322b is used for evaluating the ventilation treatment effect in the ventilation treatment time. The ventilation nodes are used to characterize the duration of the ventilation therapy, and in fig. 6, the ventilation nodes may include four, 0 hours, 2 hours, 8 hours, and 20 hours, respectively. The breathing variation trend chart 320 may be generated by: obtaining parameter values of blood oxygen saturation and respiratory rate of a patient at the beginning of timing (0 h), forming a time mark 324 of 0 hour on a two-dimensional parameter coordinate system according to the parameter values of blood oxygen saturation and respiratory rate of 0 hour, waiting for ventilation treatment time to reach 2 hours, and forming a time mark 324 of 324,8 hours and a time mark 324 of 20 hours on the two-dimensional parameter coordinate system according to the parameter values of blood oxygen saturation and respiratory rate of 2 hours, namely, the generation mode of the respiratory variation trend graph 320 is similar to a point drawing method, and each ventilation node carries out point drawing on the two-dimensional parameter coordinate system. In the present embodiment, the shape of the time stamp 324 is not limited, and may be dot-shaped as shown in fig. 6 or cross-shaped as shown in fig. 7 to 9. In some embodiments, the parameter value of the oxygenation respiration index corresponding to each ventilation node may be obtained according to the obtained blood oxygen parameter and respiration parameter of the patient, and then, in combination with the parameter value of the constant parameter set for the two-dimensional parameter coordinate system, for example, in the case that the ventilation treatment time reaches 2 hours, the parameter value of the ROX index at 2 hours is calculated according to the blood oxygen saturation of the patient at 2 hours, the respiration rate and the set inhalation oxygen concentration (at this time, the actual inhalation oxygen concentration may not be obtained, but the set inhalation oxygen concentration may be substituted into the calculation formula to obtain the parameter value of the ROX index in hundred percent), and then, the parameter value of the ROX index is displayed near the time mark 324 of 2 hours, so as to display the ROX index in a numerical form. In addition, a "time attribute" may be added to the respiratory variation trend chart 320, and specifically, the ventilation treatment time corresponding to the time stamp 324 may be displayed near the time stamp 324, for example, "8 hours" may be displayed near the time stamp 324 where the ventilation node is 8 hours. From the whole ventilation treatment process, each ventilation node divides the ventilation treatment into a plurality of treatment intervals, namely a first treatment interval of 0 to 2 hours, a second treatment interval of 2 to 8 hours, and a third treatment interval of 12 to 20 hours, and the user can pay more attention to the treatment effect after passing through one treatment interval clinically, so that the duration of the treatment interval corresponding to the time mark 324 can be displayed near the time mark 324, for example, as shown in fig. 6, the duration "6h" of the second treatment interval can be displayed above the time mark 324 with the ventilation node being 8 hours, which indicates that the time mark 324 corresponds to the ventilation treatment of the second treatment interval, and in the respiratory variation trend chart 320, the duration near the time mark 324 is the duration of the time mark 324 to the treatment interval. In addition, the time markers 324 may be connected according to the sequence of the generation, and the connection may have an arrow pointing from the previous time marker 324 to the next time marker 324, so that the breathing trend chart 320 is similar to a line chart, and the user may also know the direction of the change of the breathing trend chart 320, and in summary, may know the ventilation treatment time corresponding to each time marker 324 or the generation sequence of the time markers 324.

As can be seen from fig. 6, when the inhaled oxygen concentration is taken as a constant parameter, the two-dimensional parameter coordinate system is divided into three second areas 326, wherein the three second areas 326 are respectively an effective area, an area to be observed and an ineffective area from left to right, when a certain time mark 324 is positioned in the effective area, the nasal high flow rate oxygen therapy effect is better when the ventilation node corresponding to the time mark 324 is positioned in the effective area, when the certain time mark 324 is positioned in the area to be observed, the nasal high flow rate oxygen therapy effect is general when the ventilation node corresponding to the time mark 324 is positioned in the ineffective area, the nasal high flow rate oxygen therapy effect is poorer when the ventilation node corresponding to the time mark 324 is positioned in the ineffective area. For example, as can be seen in fig. 6, the nasal high flow rate oxygen therapy treatment effect for 2 hours and 6 hours is generally good, and the nasal high flow rate oxygen therapy treatment effect for 12 hours is better, so that the user can assist in judging the ventilation treatment effect at each ventilation node from the positional relationship between the time stamp 324 and each reference boundary.

In some embodiments, the time stamp 324 is displayed differently when it is in the second, different area 326. For example, in fig. 7, the time stamp 324 corresponding to the ventilation treatment time of 2 hours is located in the region to be observed, so its color corresponds to "close observation", and if the time stamp 324 is located in the effective region, the time stamp 324 is displayed in a color corresponding to "HFNC success rate is high".

In addition to the oxygenation respiratory index threshold, in fig. 7 to 9, the coordinate parameter threshold includes a blood oxygen saturation threshold and a respiratory rate threshold, the blood oxygen saturation threshold is 93%, two respiratory rate thresholds are 25/corresponding to a ROX valid threshold, and 30/corresponding to a ROX invalid threshold, wherein the ROX invalid threshold is 2.85, the ROX valid threshold is 3.85, and the two-dimensional parameter coordinate system can be divided into three second areas 326 by the two types of oxygenation respiratory threshold, in addition, the coordinate parameter threshold is divided into three third areas 328 from left to right in the figure, and if the time mark 324 falls into the third areas 328, the blood oxygen saturation in the third area 328 is greater than or equal to 93% and the respiratory rate is less than 25/minute, the nasal therapy flow rate is measured by the blood oxygen parameter and the respiratory parameter, and the nasal therapy is better. The third region 328 on the far right has less than 93% blood oxygen saturation and a respiration rate greater than 30 times/minute, if the time stamp 324 falls within the third region 328 on the far right, it indicates that the nasal high flow rate oxygen therapy is less effective as measured by blood oxygen parameters and respiration parameters, and if the time stamp 324 falls within the third region 328 on the middle, it indicates that the nasal high flow rate oxygen therapy is generally effective as measured by blood oxygen parameters and respiration parameters. It can be seen that the second area 326 and the third area 328 are in one-to-one correspondence, and the time stamp 324 has the same meaning as that of the corresponding second area 326 and third area 328, so that the corresponding second area 326 and third area 328 can be combined to obtain three composite areas, wherein the three composite areas are respectively an effective area from left to right, an area to be observed and an ineffective area, when a certain time stamp 324 falls into the effective area, a parameter value of a ROX index of a ventilation node corresponding to the time stamp 324 is equal to or greater than 3.85, or a blood oxygen saturation is equal to or greater than 93% and a respiration rate is less than 25/minute, then the nasal high flow rate oxygen therapy effect at this time is better, and when a certain time stamp 324 falls into the ineffective area, a parameter value of a ROX index corresponding to the ventilation node corresponding to the time stamp 324 is equal to or less than 2.85, or a blood oxygen saturation is less than 93% and a respiration rate is greater than 30 times/minute, then the nasal high flow rate oxygen therapy effect at this time is worse, and if the time stamp 324 falls into the middle area to be observed, then the nasal high flow rate oxygen therapy effect is indicated.

In fig. 7 to 9, only one blood oxygen saturation threshold is shown, and in other embodiments, the ROX valid threshold may correspond to one blood oxygen saturation threshold, and the ROX invalid threshold may correspond to the other blood oxygen saturation threshold.

Fig. 10 to 12 are alternative two-dimensional parameter coordinate systems based on the ROX index, which have the inhaled oxygen concentration and the respiration rate as parameter coordinates, the blood oxygen saturation as a constant parameter, and the parameter values of the constant parameter are more than one. Specifically, in fig. 10, the blood oxygen saturation includes three parameter values, 90%, 93%, 100%, respectively, although in other embodiments, the blood oxygen saturation may include more or less parameter values. Since the blood oxygen saturation has three parameter values, the ROX effective threshold has three corresponding effective reference boundaries 322a, i.e. three curves from bottom to top in fig. 10, and the three curves may be similar in color, for example, green with different shades. The ROX invalid threshold also has three corresponding invalid reference boundaries 322b, i.e. three curves from top to bottom in fig. 10, and the colors of the three curves may be similar, for example, red with different shades. It will be readily appreciated that the parameter values of the ROX indices represented on the three valid reference boundaries 322a are each equal to the ROX valid threshold and the parameter values of the ROX indices represented on the three invalid reference boundaries 322b are each equal to the ROX invalid threshold. Also seen from this two-dimensional coordinate system is the nasal high flow rate oxygen therapy effect of the ventilation node at a time stamp 324. For example, in fig. 10, a 2 hour time stamp 324 is located between a set of invalid reference boundaries 322b (including three invalid reference boundaries 322b corresponding to the ROX valid threshold) and a set of valid reference boundaries 322a (including three valid reference boundaries 322a corresponding to the ROX valid threshold), meaning that 2 hours of nasal hyperthermia treatment is generally effective when the patient's blood oxygen saturation is between 90% and 100%.

Fig. 13 shows a three-dimensional parameter coordinate system for the ROX index, which is different from the above two-dimensional parameter coordinate system in that there is no constant parameter. Blood oxygen saturation, respiration rate and inhaled oxygen concentration are all coordinate parameters. In other embodiments of course, if the oxygenation respiration index is obtained from four or more types of parameters, the three-dimensional parameter coordinate system also needs to set the parameter values of the constant parameters as in the two-dimensional parameter coordinate system described above. In the three-dimensional parameter coordinate system, the invalid reference boundary 322b is a reference plane, and the breathing trend graph 320 may be generated in the same manner as in the two-dimensional parameter coordinate system, and the second area 326, the third area 328, or the above-mentioned composite area is changed from a planar area to a spatial area.

In some embodiments, the processor compares the parameter value of the oxygenation respiration index with the oxygenation respiration index threshold, and outputs a prompt message according to the comparison result, and the display device can display the prompt message. The prompting information may be evaluation information, such as whether ventilation therapy is effective, whether ventilation therapy is ineffective or other evaluation information, alarm information, such as prompting patient vital sign abnormality, or operation guiding information, such as prompting a user to keep current ventilation therapy or change ventilation mode. The comparison between the parameter value of the oxygenation respiration index and the oxygenation respiration index threshold value may be either real-time comparison or intermittent comparison, for example, when the ventilation treatment time reaches a preset time, the parameter value of the oxygenation respiration index at the preset time is compared with the oxygenation respiration index threshold value, and prompt information is output according to the comparison result. The following continues to describe how to output the hint information using the ROX index in HFNC as an example.

In this embodiment, the oxygenation respiration index threshold corresponding to the ROX index includes a ROX valid threshold and a ROX invalid threshold, wherein the ROX valid threshold is greater than the ROX invalid threshold, the parameter value of the ROX index may be compared with the ROX valid threshold and the ROX invalid threshold respectively during the nasal high flow rate oxygen therapy, when the parameter value of the ROX index is greater than the ROX valid threshold, the corresponding hint information may be "keep HFNC", when the parameter value of the ROX index is less than the ROX invalid threshold, the corresponding hint information may be "stop HFNC", and when the parameter value of the ROX index is greater than or equal to the ROX invalid threshold and less than the ROX valid threshold, the corresponding hint information may be "keep HFNC and observe for a certain time".

In some embodiments, there may be a plurality of ROX valid thresholds and ROX invalid thresholds, when the ventilation treatment time reaches a certain preset time, the parameter value of the ROX index may be respectively compared with the ROX valid threshold and the ROX invalid threshold corresponding to the preset time, so as to output prompt information, for example, the ROX valid threshold includes a first ROX valid threshold, a second ROX valid threshold, a third ROX valid threshold, and the ROX invalid threshold may include a first ROX invalid threshold, a second ROX invalid threshold, and a third ROX invalid threshold.

Specifically, in a certain actual clinical treatment, when a patient is receiving nasal high flow rate oxygen therapy and the physiological parameter meets the precondition that 200mmHg is less than or equal to PaO2/FiO2 (or SpO2/FiO 2) < 300mmHg, the nasal high flow rate oxygen therapy flow rate is 40-50L/min, fiO2 is 100%, the ventilation treatment time is continuously observed for 2 hours, namely the length of ventilation treatment time is 2 hours, the first ROX effective threshold value after 2 hours of nasal high flow rate oxygen therapy is simultaneously set to be 3.85, the first ROX ineffective threshold value is 2.85, after nasal high flow rate oxygen therapy lasts for two hours, the parameter value of ROX index is respectively compared with the first ROX effective threshold value and the second ROX ineffective threshold value, when the ROX index is more than or equal to 3.85, the evaluation result is that the current nasal high flow rate oxygen therapy effect is better, and the corresponding prompt information can be 'hold HFNC'; when the ROX index is less than 2.85, the evaluation result is that the current nasal high flow rate oxygen therapy has poor curative effect, and the corresponding prompt message can be 'stop HFNC'; when the ROX index is 2.85 or more and less than 3.85, the evaluation result shows that the nasal high flow rate oxygen therapy treatment effect for the current 2 hours is general, and the corresponding prompt information can be' keep HFNC and observe for 6 hours.

Correspondingly, setting a second ROX effective threshold value to be 4.88, setting a second ROX ineffective threshold value to be 3.47, if the nasal high flow rate oxygen therapy treatment effect is general after the ventilation treatment time reaches 2 hours, comparing the parameter value of the ROX index with the second ROX effective threshold value and the second ROX ineffective threshold value after the nasal high flow rate oxygen therapy treatment is carried out for 6 hours, and when the ROX index is more than or equal to 4.88, evaluating that the current nasal high flow rate oxygen therapy treatment effect is better, and the corresponding prompt information can be 'keep HFNC'; when the ROX index is smaller than 3.47, the evaluation result is that the current nasal high flow rate oxygen therapy has poor curative effect, and the corresponding prompt message can be 'stop HFNC'; when the ROX index is 3.47 or more and less than 4.88, the evaluation result shows that the current nasal high flow rate oxygen therapy treatment effect is general, and the corresponding prompt message can be 'keep HFNC and continue to observe for 12 hours'.

Correspondingly, setting a third ROX effective threshold value to be 4.88, setting a third ROX ineffective threshold value to be 3.85, if the nasal high flow rate oxygen therapy treatment effect is common after the ventilation treatment time reaches 8 hours, comparing the parameter value of the ROX index with the third ROX effective threshold value and the third ROX ineffective threshold value after the nasal high flow rate oxygen therapy treatment is carried out for 12 hours, and when the ROX index is more than or equal to 4.88, evaluating that the current nasal high flow rate oxygen therapy treatment effect is better, and the corresponding prompt information can be 'keep HFNC'; when the ROX index is less than 3.85, the evaluation result is that the current nasal high flow rate oxygen therapy has poor curative effect, and the corresponding prompt message can be 'stop HFNC'; when the ROX index is greater than or equal to 3.85 and less than 4.88, the evaluation result shows that the current nasal high flow rate oxygen therapy curative effect is general, and the corresponding prompt message can be 'keep HFNC and observe for a certain time'.

In general clinical treatment, after three periods of nasal high flow rate oxygen therapy of 2 hours, 6 hours and 12 hours (the corresponding ventilation nodes are 2 hours, 8 hours and 20 hours), if the ROX index of the patient is calculated to still not reach the standard for evaluating the better curative effect of nasal high flow rate oxygen therapy, HFNC is stopped, and the reason for the situation is probably that the patient is conscious disturbance, malignant arrhythmia, severe shock, acute respiratory acidosis or airway drainage disturbance, etc., and then the patient is changed into non-invasive ventilation (NIV) or tracheal intubation invasive ventilation.

In the case that the ROX valid threshold and the ROX invalid threshold have a plurality, the trend graph of the ROX index also adjusts the boundary of the first area 314 according to the plurality of ROX valid thresholds and the ROX invalid threshold, specifically, in fig. 4, the ROX valid threshold is equal to 4.88, the ROX invalid threshold includes a first ROX invalid threshold and a second ROX invalid threshold, wherein the first ROX invalid threshold is 3.85, the second ROX invalid threshold is 2.85, it can be seen that the ventilation treatment time is from 2 hours to 20 hours, the ROX valid threshold is unchanged, and the ventilation treatment time is between 2 hours to 10 hours, the parameter value of the ROX index is to be compared with the first ROX invalid threshold, which means that if the parameter value of the ROX index is lower than 3.85 during this period, the effect of oxygen therapy through nasal high flow is general, and the parameter value of the ROX index is to be compared with the second ROX invalid threshold when the ventilation treatment time is between 10 hours to 20 hours.

In addition to the way the boundary lines 316 of the first region 314 are changed, the boundary lines 316 may be marked as shown in fig. 2 to 3 to represent ventilation nodes with a change in the threshold value of the oxygenation respiration index, and in fig. 2, the ventilation treatment time is from 2 hours to 8 hours, the parameter value of the ROX index and the two thresholds of 3.85 and 2.85 are compared, and it is seen that marks with dots are displayed on the two boundary lines 316 representing 3.85 and 2.85, respectively, to represent that the two thresholds of 3.85 and 2.85 are compared with the parameter value of the ROX index from the ventilation node of 2 hours.

In the case that there are multiple ROX valid thresholds and ROX invalid thresholds, the above parameter coordinate system may correspondingly adjust the positions of the reference boundaries, specifically refer to the embodiment shown in fig. 7 to 12, where the ROX valid thresholds include a first ROX valid threshold and a second ROX valid threshold, and the ROX invalid threshold includes a first ROX valid threshold, a second ROX invalid threshold and a third ROX invalid threshold (or may also be considered to have a third ROX valid threshold, and the third ROX valid threshold and the third invalid threshold are equal), as shown in fig. 7 and fig. 10, where the parameter value of the ROX index on the valid reference boundary 322a is equal to the first ROX valid threshold, and the parameter value of the ROX index on the invalid reference boundary 322b is equal to the first ROX invalid threshold, where the first ROX valid threshold is 3.85, and the first ROX invalid threshold is 2.85; as shown in fig. 8 and 11, which may represent a graph 320 of the trend of respiratory change after a ventilation treatment time of 8 hours (6 h in the graph represents that ventilation was continued for 6h since the last ventilation node), the parameter value of the ROX index on the effective reference boundary 322a is equal to a second ROX effective threshold, and the parameter value of the ROX index on the ineffective reference boundary 322b is equal to a second ROX ineffective threshold, wherein the second ROX effective threshold is 4.88 and the second ROX ineffective threshold is 3.85; as shown in fig. 9 and 12, which show a graph 320 of the trend of respiratory change after a ventilation treatment time of 20 hours (12 hours in the figure indicates that the treatment was continued for 12 hours since the last ventilation node), the parameter value of the ROX index on the invalid reference boundary 322b in the figure is equal to a third ROX invalid threshold, wherein the third ROX invalid threshold is 4.88.

In some embodiments, the processor 170 may further compare the parameter value of the blood oxygen parameter with the blood oxygen parameter threshold, and the parameter value of the respiratory parameter with the respiratory parameter threshold, so as to evaluate the ventilation treatment effect, and may also output corresponding prompt information, where the blood oxygen parameter reference value and the respiratory parameter reference value may be stored by default in the system, or may be input by a user operation. The user may input an operation by touching the display screen directly or by an external input device (keyboard, mouse, or wheel).

In this embodiment, the blood oxygen parameter is exemplified by blood oxygen saturation, the respiratory parameter is exemplified by respiratory rate, and a flow of evaluation results of the therapeutic effect of nasal high flow rate oxygen therapy is generated according to the blood oxygen saturation and respiratory rate. Specifically, the evaluation result may be that the current nasal high flow rate oxygen therapy has better curative effect, and the corresponding prompt message may be "keep HFNC"; the evaluation result can be that the current nasal high flow rate oxygen therapy has poor curative effect, and the corresponding prompt message can be 'stop HFNC'; the evaluation result can be that the current nasal high flow rate oxygen therapy curative effect is general, and the corresponding prompt information can be 'keep HFNC and observe for a certain time'.

In some embodiments, the blood oxygen saturation threshold and the respiration rate threshold may be plural, and the first respiration rate threshold, the second respiration rate threshold, the third respiration rate threshold, and the like are sequentially the first blood oxygen saturation threshold, the second blood oxygen saturation threshold, the third blood oxygen saturation threshold, and the like in time sequence. The following examples are illustrative.

In a certain actual clinical treatment, when a patient is receiving nasal high flow rate oxygen therapy, physiological parameters meet the precondition that 200mmHg is less than or equal to PaO2/FiO2 (or blood oxygen saturation/FiO 2) < 300mmHg, setting the nasal high flow rate oxygen therapy flow rate to be 40-50L/min, fiO2 to be 100%, continuously observing for 2 hours, namely, setting the nasal high flow rate oxygen therapy time length to be 2 hours, simultaneously setting a first blood oxygen saturation threshold value after 2 hours nasal high flow rate oxygen therapy to be 93%, setting a first respiratory rate threshold value to be 25 times/min, setting a second respiratory rate threshold value to be 30 times/min, comparing the parameter value of blood oxygen saturation with the first blood oxygen saturation threshold value after the ventilation treatment time reaches 2 hours, and respectively comparing the parameter value of respiratory rate with the first respiratory rate threshold value and the second respiratory rate threshold value, wherein when the parameter value of blood oxygen saturation is more than or equal to 93% and the parameter value of respiratory rate is less than 25 times/min, the evaluation result is that the current nasal high oxygen therapy time is better, corresponding HFNC can keep the treatment effect; when the parameter value of the blood oxygen saturation is less than 93% and the parameter value of the respiratory rate is more than or equal to 30 times/time sharing, the evaluation result is that the current nasal high flow rate oxygen therapy has poor curative effect, and the corresponding prompt information can be 'stop HFNC'; when the parameter value of the blood oxygen saturation is greater than or equal to 93% and the parameter value of the respiratory rate is greater than or equal to 25 times/min and less than 30 times/min, the evaluation result shows that the current nasal high flow rate oxygen therapy curative effect is general, and the corresponding prompt message can be 'continuing HFNC observation for 6 hours'.

Correspondingly, the second blood oxygen saturation threshold value is 93%, the third respiratory rate threshold value is 20 times/min, the fourth respiratory rate threshold value is 25 times/min, if the nasal high flow rate oxygen therapy treatment effect is general at 2 hours, after the nasal high flow rate oxygen therapy treatment for 6 hours (the ventilation treatment time reaches 8 hours) is finished, the parameter value of the blood oxygen saturation is compared with the second blood oxygen saturation threshold value, the parameter value of the respiratory rate is respectively compared with the third respiratory rate threshold value and the fourth respiratory rate threshold value, when the parameter value of the blood oxygen saturation is greater than or equal to 93% and the parameter value of the respiratory rate is less than 20 times/min, the evaluation result is that the current nasal high flow rate oxygen therapy treatment effect is better, and the corresponding prompt information can be 'continuously holding HFNC'; when the parameter value of the blood oxygen saturation is less than 93% and the parameter value of the respiratory rate is more than or equal to 25 times/time sharing, the evaluation result is that the current nasal high flow rate oxygen therapy has poor curative effect, and the corresponding prompt information can be 'stop HFNC'; when the parameter value of the blood oxygen saturation is more than or equal to 93% and the parameter value of the respiratory rate is more than or equal to 20 times/min and less than 25 times/min, the evaluation result is that the current nasal high flow rate oxygen therapy curative effect is general, and the corresponding prompt information can be 'continuously hold HFNC and continuously observe for 12 hours'.

Correspondingly, a third blood oxygen saturation threshold value is 93%, a fifth respiratory rate threshold value is 25 times/min, a sixth respiratory rate threshold value is 30 times/min, if the nasal high flow rate oxygen therapy treatment effect is general at 6 hours, after the nasal high flow rate oxygen therapy treatment is finished for 12 hours, the parameter value of the blood oxygen saturation is compared with the third blood oxygen saturation threshold value, the parameter value of the respiratory rate is respectively compared with the fifth respiratory rate threshold value and the sixth respiratory rate threshold value, when the parameter value of the blood oxygen saturation is greater than or equal to 93% and the parameter value of the respiratory rate is smaller than 25 times/min, the evaluation result is that the current nasal high flow rate oxygen therapy treatment effect is better, and the corresponding prompt information can be 'keep HFNC'; when the parameter value of the blood oxygen saturation is less than 93% and the parameter value of the respiratory rate is more than or equal to 30 times/time sharing, the evaluation result is that the current nasal high flow rate oxygen therapy has poor curative effect, and the corresponding prompt information can be 'stop HFNC'; when the parameter value of the blood oxygen saturation is greater than or equal to 93% and the parameter value of the respiratory rate is greater than or equal to 25 times/min and less than 30 times/min, the evaluation result is that the current nasal high flow rate oxygen therapy curative effect is general, and the corresponding prompt information can be 'continuing HFNC to observe for a certain time'.

The above-mentioned multiple blood oxygen saturation thresholds and respiration rate thresholds, and the length of time (or the length of each treatment interval) for providing nasal high flow oxygen therapy are merely illustrative, and not limiting the scope of the present invention, which is mainly protected by the concept of comparing the parameter values of the blood oxygen parameters and the parameter values of the respiration parameters with the multiple blood oxygen parameter thresholds and the respiration parameter thresholds to generate the evaluation result, and further protecting the concept of setting multiple ventilation therapies, each of which may be different in length of time, and setting different blood oxygen parameter thresholds and respiration parameter thresholds for the ventilation therapies of different lengths of time in combination with the duration of ventilation therapy that the patient has already accepted. Clinically, the blood oxygen parameter threshold value and the respiratory parameter threshold value, and the ventilation treatment time length can be set by a user according to experience, specific conditions of a patient or corresponding guiding standards, or can be preset by a system.

As shown in fig. 14, a threshold setting interface 400 is provided, the oxygenation respiration index is a ROX index, the blood oxygen parameter is blood oxygen saturation, and the respiration parameter is respiration rate. In this figure, a ROX improvement threshold, a ROX lower limit threshold, a respiration rate upper limit threshold, and a blood oxygen saturation lower limit threshold may be set. In the figure, when the blood oxygen saturation is higher than 93%, the ventilation treatment is started to be timed, and when the ventilation treatment time reaches 2 hours, if the parameter value of the ROX index is more than or equal to 3.85 and the respiration rate is less than or equal to 30 times/minute, the treatment effect of the nasal high flow rate oxygen treatment is better, otherwise, the treatment effect of the nasal high flow rate oxygen treatment is poorer; when the ventilation treatment time reaches 8 hours, if the parameter value of the ROX index is more than or equal to 2.85 and the respiratory rate is less than or equal to 30 times/min, the treatment effect of nasal high flow rate oxygen therapy is better, otherwise, the treatment effect of nasal high flow rate oxygen therapy is poorer; when the ventilation treatment time reaches 12 hours, if the parameter value of the ROX index is more than or equal to 4.85, the treatment effect of nasal high flow rate oxygen therapy is better, otherwise, the treatment effect of nasal high flow rate oxygen therapy is poorer. In addition, in fig. 14, the "continuously prompting" key is in an on state, so after the parameter value of the ROX index is compared with the threshold value by a certain ventilation node, the display device 180 may display the corresponding prompting information until the next ventilation node.

Another threshold setting interface 400 is shown in fig. 15-16, in which the oxygenation respiration index is a ROX index. The ROX low risk threshold may correspond to the ROX valid threshold above, and the ROX high risk threshold may correspond to the ROX invalid threshold above. In fig. 15 and 16, a button may be clicked to restart the timing of the ventilation treatment time.

As shown in fig. 17, another threshold setting interface 400 is shown, in this embodiment, the oxygenation respiration index is a ROX index, the blood oxygen parameter is blood oxygen saturation, and the respiration parameter is respiration rate. The treatment interval is not distinguished in the setup interface, and the oxygenation respiration index threshold, the blood oxygenation parameter threshold, and the respiration parameter threshold are the same throughout the ventilation treatment.

The setting of the oxygenation respiration index threshold, the blood oxygen parameter threshold and the respiration parameter threshold can be set before the ventilation treatment starts, and can be changed in the ventilation treatment process. In addition, the setting of the parameter value of the constant parameter may be set before the ventilation therapy or may be changed during the ventilation therapy.

The above-described oxygenation-respiratory-index threshold value, blood-oxygen-parameter threshold value, and respiratory threshold value may be combined to evaluate the effect of ventilation therapy, or the respective threshold values may be set together on the setting interface. For example, in some embodiments, if the parameter value of the ROX index is greater than or equal to 3.85 or the blood oxygen saturation is greater than or equal to 93% and the respiratory rate is less than 25/min after the HFNC reaches two hours, the nasal high flow rate oxygen therapy is better, and it can be seen that the composite area shown in fig. 7 to 9 is a schematic diagram for evaluating the ventilation therapy by combining the oxygenation respiration index threshold, the blood oxygen parameter threshold and the respiration threshold.

In view of the foregoing, it can be seen that the present invention can automatically calculate the real-time parameter value of the oxygenation respiration index, generate the oxygenation respiration index trend chart 310a and the respiration variation trend chart 320 according to the parameter value of the oxygenation respiration index, and compare the parameter value of the oxygenation respiration index with the oxygenation respiration index threshold value and output the corresponding prompt information, and the foregoing modes are not isolated but can be combined with each other.

Taking the ROX index as an example, fig. 2 is a schematic diagram of an oxygenation presenting interface 300, where the oxygenation presenting interface 300 includes: real-time parameter values of the ROX index during nasal high flow rate oxygen therapy; real-time parameter values of physiological parameters during nasal high flow rate oxygen therapy; the trend graph of the ROX index in the nasal high flow rate oxygen therapy process is shown in a waveform mode, the trend graph of the ROX index is provided with a time line 312 perpendicular to the horizontal axis (time axis), the time line 312 can translate along the horizontal axis in response to operation input of a user, the time line 312 is intersected with the trend waveform of the ROX index and displays historical parameter values of the ROX index corresponding to the intersection point, and adjacent areas of the trend graph of the ROX index can synchronously display the parameter values of the ROX parameter and the physiological parameter at the historical time.

Fig. 3 is a schematic diagram of another oxygenation prompting interface 300, in which an oxygenation prompting interface 300 is shown: real-time parameter values of the ROX index during nasal high flow rate oxygen therapy; real-time parameter values of physiological parameters during nasal high flow rate oxygen therapy; a trend chart of ROX index in the nasal high flow rate oxygen therapy process, a trend chart of blood oxygen parameter and respiratory parameter in the nasal high flow rate oxygen therapy process, wherein the blood oxygen parameter is blood oxygen saturation, and the respiratory parameter is respiratory rate; the current prompt message of nasal high flow rate oxygen therapy "continue HFNC".

Fig. 4 is a schematic diagram of yet another oxygenation prompting interface 300, in which an oxygenation prompting interface 300 is displayed: real-time parameter values of the ROX index during nasal high flow rate oxygen therapy; real-time parameter values of physiological parameters during nasal high flow rate oxygen therapy; a trend graph of the ROX index and a trend graph of the physiological parameter in the nasal high flow rate oxygen therapy process, wherein the trend graph of the physiological parameter is a trend graph of the concentration of inhaled oxygen and a trend graph of airway flow rate.

Fig. 5 is a schematic diagram of yet another oxygenation prompting interface 300, in which an oxygenation prompting interface 300 is displayed: real-time parameter values of the ROX index during nasal high flow rate oxygen therapy; real-time parameter values of physiological parameters during nasal high flow rate oxygen therapy; a trend table of ROX index and physiological parameters in the nasal high flow rate oxygen therapy process, wherein the physiological parameters are blood oxygen saturation and respiratory rate; current prompt for nasal high flow rate oxygen therapy.

The above-mentioned oxygenation prompting interface 300 may be a certain display area on the ventilation interface, or may be displayed on the same screen as the ventilation interface, or may pop up based on the operation of the user, or when certain conditions are met, the processor 170 controls the ventilation interface to switch to the oxygenation prompting interface 300. In some embodiments, when the processor 170 detects that the parameter value of the oxygenation respiration index is below a predetermined lower limit value, the display device 180 is controlled to switch the ventilation interface to the oxygenation-prompting interface 300.

In some embodiments, the oxygenation respiratory index can also be used in conjunction with other physiological parameters to evaluate the effectiveness of ventilation therapy, e.g., the heart rate and/or pulse rate of the patient can also be obtained and then combined with the oxygenation respiratory index, e.g., the ROX index, can be used to evaluate the efficacy of HFNC based on ROX-HR, where ROX-HR = ROX/HR, HR being the heart rate of the patient. The evaluation parameters such as ROX-HR are used in a manner similar to those described above for the oxygenation respiration index, and will not be described in detail herein.

Referring to the embodiment shown in fig. 18, the embodiment further provides a monitoring device 500, where the monitoring device 500 is configured to monitor physiological parameters of a patient during ventilation therapy, the physiological parameters include, but are not limited to, blood oxygen parameters including, but not limited to, percutaneous blood oxygen saturation (SpO 2), arterial blood oxygen partial pressure (PaO 2), and arterial blood oxygen saturation (SaO 2), and respiratory parameters including, but not limited to, respiratory Rate (RR) of the patient and respiratory oxygen partial pressure (FiO 2). The monitoring device 500 includes, but is not limited to, a monitor, a central station, a medical information system, such as a HIS, and a medical mobile terminal, such as a PDA or a mobile PC, a mobile phone, etc., that is held by a medical staff. The ventilation therapy may include (transnasal) high flow rate oxygen therapy, noninvasive ventilation therapy, invasive ventilation therapy, etc

In particular, the monitoring device 500 can include a sensor 510, a memory 520, a human interaction device 530, a processor 540, and a display device 550. It should be understood that fig. 18 is merely an example of the monitoring device 500 and is not meant to be limiting of the monitoring device 500, and that when the monitoring device 500 is a specific type of instrument, more or fewer components than shown in fig. 18 may be included, or certain components may be combined, or different components may be included.

The sensor 510 is for real-time acquisition of a physiological parameter of a patient during ventilation therapy, and the sensor 510 may include one or more. In some embodiments, the monitoring device 500 further comprises a communication device 560, the communication device 560 being configured to receive externally transmitted blood oxygen parameters and respiratory parameters of the patient, that is, in this embodiment, the monitoring device 500 itself does not acquire blood oxygen parameters and respiratory parameters to be processed later, but acquires them by other medical devices and then transmits them to the monitoring device 500 for processing, while in other embodiments, the sensor 510 and the communication device 560 may be combined, for example, the monitoring device 500 itself acquires blood oxygen parameters in real time via the sensor 510, and receives externally transmitted respiratory parameters via the communication device 560 and then processes the respiratory parameters and the blood oxygen parameters.

The monitoring device 500 may receive the input command signal through the human interaction device 530. The human-machine interaction device 530 may include one or more of a keyboard, a mouse, a wheel, a mobile input device (e.g., a mobile device with a touch screen, a mobile phone, etc.), etc.

The processor 540 is configured to execute instructions or programs, process received data, generate desired calculation or determination results, or generate visual data or graphics, and output the visual data or graphics to the display device 550 for display.

The display device 550 is configured to display a monitoring interface on which some or all of the at least one physiological parameter is displayed, the display device 550 may include one or more display screens, and each display screen may be a touch display screen or a non-touch display screen, and when the display device 550 includes a touch display screen, the touch display screen may also be a part of the human-machine interaction device 530, and receive an instruction from a user in response to a touch operation by the user.

In this embodiment, the processor 540 is configured to, upon detecting that the timing condition is satisfied, start timing the ventilation therapy of the patient and obtain a ventilation therapy time based on the timing. The processor 540 generates an oxygenated respiratory index corresponding to the ventilation therapy time based on the blood oxygen parameter and the respiratory parameter, and the oxygenated respiratory index is used to evaluate the ventilation therapy effect during the corresponding ventilation therapy time. The oxygenation respiration index comprises at least one of a ROX index, an oxygenation index (P/F), an Oxygen Index (OI), and a pulse Oxygen Saturation Index (OSI). Wherein, the calculation formula of the ROX index is:

After generating the oxygenation respiration index, similar to the respiration support apparatus 100 described above, the monitoring apparatus 500 may calculate and display real-time parameter values of the oxygenation respiration index, may generate the oxygenation respiration index trend map 310a and the respiration variation trend map 320 according to the parameter values of the oxygenation respiration index, and may also compare the parameter values of the oxygenation respiration index with the oxygenation respiration index threshold value and output corresponding prompt information. The difference is that the above-mentioned oxygenation prompting interface 300 may be a certain display area on the monitoring interface, or may be displayed on the same screen as the monitoring interface, or may pop up based on the operation of the user, or when certain conditions are met, the processor 540 controls the monitoring interface to switch to the oxygenation prompting interface 300. In some embodiments, when the processor 540 detects that the parameter value of the oxygenation respiration index is below a predetermined lower limit, the display device 550 is controlled to switch the monitoring interface to the oxygenation-prompting interface 300.

The present application further provides a medical device system 1000, where the medical device system 1000 includes a plurality of medical devices, and the plurality of medical devices include a parameter acquiring device, the medical device including the parameter acquiring device is configured to send an acquired blood oxygen parameter and a respiratory parameter during ventilation treatment of a patient to another medical device, where the medical device may include, but is not limited to, a ventilator, an anesthesia machine, an oxygen therapy apparatus, a monitor, a central station 600, a medical information system, or a medical mobile terminal, the blood oxygen parameter includes, but is not limited to, a percutaneous blood oxygen saturation (SpO 2), an arterial blood oxygen partial pressure (PaO 2), and an arterial blood oxygen saturation (SaO 2), the respiratory parameter includes, but is not limited to, an inhalation oxygen partial pressure (FiO 2), and a Respiratory Rate (RR) of the patient, and the medical device that receives the blood oxygen parameter and the respiratory parameter may generate an oxygenation respiratory index corresponding to a ventilation treatment time according to the blood oxygen parameter and the respiratory parameter, and the oxygenation respiratory index is configured to evaluate a ventilation treatment effect within the ventilation treatment time corresponding to the oxygenation respiratory index.

After obtaining the oxygenation respiration index, the medical device may calculate and display a real-time parameter value of the oxygenation respiration index, may generate an oxygenation respiration index trend chart 310a and a respiration change trend chart 320 according to the parameter value of the oxygenation respiration index, and may compare the parameter value of the oxygenation respiration index with the oxygenation respiration index threshold value and output corresponding prompt information. For example, in fig. 19, the medical device system 1000 includes the respiratory support device 100, the monitoring device 500, and the central station 600, the respiratory support device 100 includes a sensor as a parameter acquisition means, and the sensor of the respiratory support device 100 may acquire a respiratory parameter of a patient in ventilation therapy, the monitoring device 500 also includes a sensor as a parameter acquisition means, the sensor of the monitoring device 500 is used to acquire a blood oxygen parameter of the patient in ventilation therapy, the respiratory support device 100 transmits the acquired respiratory parameter to the central station 600, the monitoring device 500 transmits the acquired blood oxygen parameter to the central station 600, and the central station 600 calculates an oxygenation respiratory index from the acquired respiratory parameter and the blood oxygen parameter.

In some embodiments, each medical device in the medical device system 1000 includes a parameter acquiring device, where the medical device system 1000 may include the respiratory support device 100 and the monitoring device 500, where the respiratory support device 100 may acquire respiratory parameters of a patient, and where the monitoring device 500 may acquire blood oxygen parameters of the patient, when calculating an oxygenation respiratory index, the monitoring device 500 may send the blood oxygen parameters to the respiratory support device 100, where the oxygenation respiratory index is calculated by the respiratory support device 100, or where the respiratory support device 100 sends the respiratory parameters to the monitoring device 500, where the oxygenation respiratory index is calculated by the monitoring device 500.

The application also provides a parameter processing method of the medical equipment system, as shown in fig. 20, comprising the following steps:

and step S100, when the timing condition is detected to be met, starting timing the ventilation treatment of the patient, and obtaining the ventilation treatment time according to the timing.

For example, when the user starts timing after pressing an entity or virtual key to start timing, or when it is detected that ventilation therapy is started, in some embodiments, it is first determined whether a physiological parameter of the patient meets a precondition, and the ventilation therapy time is started to be calculated when the precondition is met, for example, in nasal high flow oxygen therapy (HFNC), the precondition may be set to PaO2/FiO2 (or SpO2/FiO 2) > 150mmHg, and in some cases, the precondition may be set to 200 mmHg. Ltoreq. PaO2/FiO2 (or SpO2/FiO 2) < 300mmHg. In clinical treatment, the precondition is generally satisfied, the foundation for performing treatment effect evaluation is considered to exist when the nasal high-flow rate oxygen therapy is performed secondarily, and if the current sign parameters of the patient do not satisfy the precondition, the treatment effect evaluation of the nasal high-flow rate oxygen therapy cannot be performed or the evaluation result is considered to have a large error.

Step S200, obtaining blood oxygen parameters and respiratory parameters of a patient. Among them, blood oxygen parameters include, but are not limited to, percutaneous blood oxygen saturation (SpO 2), arterial blood oxygen partial pressure (PaO 2), and arterial blood oxygen saturation (SaO 2), and respiratory parameters may include, but are not limited to, the partial pressure of inhaled oxygen (FiO 2) and the Respiratory Rate (RR) of the patient.

Step S300, generating an oxygenation respiration index corresponding to the ventilation treatment time according to the blood oxygenation parameter and the respiration parameter. The oxygenation respiration index is used for evaluating the ventilation treatment effect in the ventilation treatment time corresponding to the oxygenation respiration index. The oxygenation respiration index comprises at least one of a ROX index, an oxygenation index (P/F), an Oxygen Index (OI), and a pulse Oxygen Saturation Index (OSI). Wherein, the calculation formula of the ROX index is:

In some embodiments, step S300 is followed by:

step 400a, outputting real-time parameter values of the oxygenation respiration index.

As shown in fig. 2-5, real-time parameter values of the oxygenation respiration index may be displayed. The display of the oxygenation respiration index is understood to mean that the oxygenation respiration index is displayed directly on the ventilation interface, or that the parameter value of the oxygenation respiration index is called out by a user operation to display on the ventilation interface. In addition to acquiring the parameter values of the oxygenation respiration index in real time (continuously), the parameter values of the oxygenation respiration index may also be acquired at intervals, for example, when the ventilation treatment time reaches 2 hours, 8 hours, and 20 hours, the parameter values of the oxygenation respiration index are obtained and the parameter values are displayed, respectively. Furthermore, the parameter values of the blood oxygen parameter and the parameter values of the respiratory parameter may be displayed simultaneously, wherein the simultaneous display is understood to mean that when the parameter values of the oxygenation respiratory index are real-time, the parameter values of the blood oxygen parameter and the parameter values of the respiratory parameter are also real-time, and when the parameter values of the oxygenation respiratory index are at a certain point in time (e.g. 2 h), the parameter values of the blood oxygen parameter and the parameter values of the respiratory parameter are also at that point in time (e.g. 2 h).

In some embodiments, step S300 is followed by:

step S400b, generating an oxygenation respiration index trend chart and/or an oxygenation respiration index trend table of oxygenation respiration indexes changing with time.

The oxygenation-respiration-index trend chart 310a may be a waveform chart, a line chart, a bar chart, a dial or other graphical display means, and reflects continuous or intermittent calculation and monitoring of the oxygenation respiration index, and the oxygenation-respiration-index trend chart 310b further reflects intermittent calculation and monitoring of the oxygenation respiration index at certain specific moments. In fig. 2-4, the oxygenation respiration index trend chart 310a is a waveform chart including trend waveforms of oxygenation respiration index with time. The method can also generate the change trend of the blood oxygen parameter and the change trend of the respiratory parameter, and can simultaneously display the change trend of the oxygenation respiratory index, the change trend of the blood oxygen parameter and the change trend of the respiratory parameter. The trend of the change of the blood oxygen parameter can be shown in the form of a blood oxygen parameter trend chart or a blood oxygen parameter trend table, and the trend of the change of the respiratory parameter can be shown in the form of a respiratory parameter trend chart or a respiratory parameter trend table. For example, in fig. 3, a trend graph with a ROX index is shown, together with a trend graph with blood oxygen saturation and a trend graph with respiration rate. In other embodiments, only the trend of the oxygenation respiration index and the trend of the blood oxygen parameter may be displayed, or only the trend of the oxygenation respiration index and the trend of the respiration parameter may be displayed, or the trend of the oxygenation respiration index and the trend of other physiological parameters may be displayed.

In fig. 3 and 4, the oxygenation-respiration-index trend chart 310a, the blood-oxygen-parameter trend chart, and the respiration-parameter trend chart are each formed with a time line 312, and the positions of the time lines 312 in each trend chart represent the same time, whereas in fig. 3, the blood-oxygen-parameter trend chart and the respiration-parameter trend chart share one coordinate system, so that they share one time line 312. When the user moves one of the time lines 312 (e.g., drags the time line 312 with a mouse), the other time lines 312 move with it, so that the time lines 312 on each trend graph remain characteristic of the same time. The parameter values of the oxygenation respiration index, the parameter values of the blood oxygenation parameter, and the parameter values of the respiration parameter at the time indicated by the time line 312 may be output, and for example, a parameter value of the ROX index at the time corresponding to the time line 312 of 4.23, a parameter value of the blood oxygenation saturation of 94%, and a parameter value of the respiration rate of 24/minute are shown in fig. 3. In addition, in the absence of the blood oxygen parameter trend graph and the respiratory parameter trend graph, the time line 312 may be displayed only on the oxygenation respiration index trend graph 310a, for example, as shown in fig. 2, in which the time line 312 may be used to select a historical parameter value of the oxygenation respiration index.

In addition to the above-described parameter values that are displayed by moving the time-scale line 312 to determine when to display, the user-selected historical time may be determined based on a time-selection instruction entered by the user for the oxygenation-respiration-index trend map 310a, which may be entered by the user directly in touch with the touch-sensitive display screen, such as by a finger touching a portion of the oxygenation-respiration-index trend map 310a, or by an external input device (keyboard, mouse, or wheel). Of course, after the above-mentioned historical time is determined, the parameter values of the blood oxygen parameter and/or the parameter values of the respiratory parameter at the same historical time may be displayed at the same time, so that the user may conveniently check the historical parameter values of the oxygenation respiratory index, the blood oxygen parameter and the respiratory parameter.

The oxygenation respiration index trend chart 310a may be further divided into at least two first areas 314 extending along the time axis by taking the oxygenation respiration index threshold as a boundary according to at least one oxygenation respiration index threshold, wherein the oxygenation respiration index threshold may be set as a default stored threshold of the system or may be input by a user operation, wherein the user operation input may be a touch operation directly on a touch display screen or an operation through an external input device (a keyboard, a mouse or a roller), and the effect of ventilation treatment may be evaluated according to which first area 314 the trend waveform falls in the oxygenation respiration index trend chart 310 a.

The following will specifically describe the ROX index in HFNC therapy. In this embodiment, the oxygenation respiration index threshold corresponding to the ROX index includes two types, specifically, a ROX valid threshold and a ROX invalid threshold, where the ROX valid threshold is greater than the ROX invalid threshold. In other embodiments herein, the oxygenation respiration index threshold corresponding to the ROX index may be at least one of a ROX valid threshold and a ROX invalid threshold, or other types or values of thresholds. The trend graph of the ROX index in fig. 4 is divided into three first areas 314 by a ROX effective threshold and a ROX ineffective threshold, wherein when the trend waveform of the ROX index is located in the first area 314 at the top, it means that the nasal high flow rate oxygen therapy effect is better, the HFNC can be continuously maintained, when the trend waveform of the ROX index is located in the first area 314 at the middle, it means that the nasal high flow rate oxygen therapy effect is general, the HFNC can be continuously maintained and observed for a period of time, and when the trend waveform of the ROX index is located in the first area 314 at the bottom, it means that the nasal high flow rate oxygen therapy effect is poor, the HFNC can be stopped and other more "powerful" ventilation therapy modes can be used instead.

As shown in fig. 5, when the trend of the change in the ROX index is shown in the form of a trend table, three threshold ranges may be determined by the ROX effective threshold and the ROX ineffective threshold, each of which corresponds to the map of the first region 314, and parameter values of the ROX index falling within the different threshold ranges may be displayed in different manners, for example, in the trend table of the ROX index, parameter values of the ROX index greater than the ROX effective threshold are displayed in green, and parameter values of the ROX index less than the ROX ineffective threshold are displayed in red.

In addition, the oxygenation respiratory index threshold may have a plurality, for example, in the case that the ROX valid threshold and the ROX invalid threshold have a plurality, the trend graph of the ROX index may also adjust the boundary of the first area 314 according to the plurality of the ROX valid threshold and the ROX invalid threshold, specifically, in fig. 4, the ROX valid threshold is equal to 4.88, the ROX invalid threshold includes a first ROX invalid threshold and a second ROX invalid threshold, wherein the first ROX invalid threshold is 3.85, the second ROX invalid threshold is 2.85, it can be seen that the ventilation treatment time is from 2 hours to 20 hours, the ROX valid threshold is unchanged, and the ventilation treatment time is between 2 hours to 10 hours, which means that if the parameter value of the ROX index is lower than 3.85 during the period, the ventilation treatment effect is generally achieved through high oxygen therapy, and the parameter value of the ROX index is compared with the second ROX invalid threshold when the ventilation treatment time is between 10 hours to 20 hours.

In some embodiments, step S300 is followed by:

step S400c, a parameter coordinate system is established, and a respiration variation trend chart with time variation of the coordinate parameters is generated in the parameter coordinate system.

The parameter coordinate system is established by setting at least two types of parameters of both the blood oxygen parameter and the respiratory parameter as coordinate parameters. One coordinate axis of the parameter coordinate system corresponds to one coordinate parameter, and the possible types of the blood oxygen parameter and the respiratory parameter are fully described above, which are not described herein, and the oxygenation respiratory index can be calculated through the blood oxygen parameter and the respiratory parameter. How to build the parameter coordinate system and how to apply the parameter coordinate system is also described below in terms of a ROX index in HFNC, wherein the corresponding oxygenated breathing index threshold value of the ROX index may comprise at least one of a ROX valid threshold value and a ROX invalid threshold value, and the ROX valid threshold value is greater than the ROX invalid threshold value. For other ventilation therapy regimes, and other types of oxygenation respiration index, more or fewer oxygenation respiration index thresholds than the examples set forth below may be included, as well as more or fewer types of blood oxygenation parameters and respiration parameters.

Fig. 6 to 9 show a two-dimensional parameter coordinate system with respect to the ROX index, in which the respiration rate and the blood oxygen saturation are coordinate parameters, and in which the respiration rate corresponds to the abscissa and the blood oxygen saturation corresponds to the ordinate, and the other inhaled oxygen concentration is set as a constant parameter, which means that the parameter value of the parameter is a changeable fixed amount, for example, in fig. 6 to 9, the inhaled oxygen concentration is fixedly set to one hundred percent. At least one of an effective reference boundary 322a corresponding to the ROX effective threshold and an ineffective reference boundary 322b corresponding to the ROX ineffective threshold are generated on the two-dimensional parameter coordinate system, respectively. The meaning of the active reference boundary 322a is: if any point on the effective reference boundary 322a is taken, the abscissa and the ordinate corresponding to the point are brought into the calculation formula of the ROX index, and then the set constant parameters are set: the value of the parameter of the resulting ROX index is equal to the ROX effective threshold, and the meaning of the ineffective reference boundary 322b is similar to that of the effective reference boundary 322a, so that two points can be seen: 1. the parameter value of the ROX index represented by each point on the valid reference boundary 322a is equal to the ROX valid threshold, while the parameter value of the ROX index represented by each point on the invalid reference boundary 322b is equal to the ROX invalid threshold; 2. the positions of the valid reference boundary 322a and the invalid reference boundary 322b in the two-dimensional parameter coordinate system are associated with not only the ROX valid threshold and the ROX invalid threshold, but also the parameter values of the constant parameters set in the two-dimensional parameter coordinate system. It will be readily appreciated that in other embodiments, if only two types of parameters are required to obtain the oxygenation respiration index, then no constant parameters exist for the corresponding two-dimensional parameter coordinate system.

After the two-dimensional parameter coordinate system is generated, according to the parameter values of the corresponding coordinate parameters of the plurality of ventilation nodes in the ventilation treatment time, a respiration variation trend chart 320 with the time variation of the coordinate parameters is generated in the two-dimensional parameter coordinate system, the two-dimensional parameter coordinate system and the respiration variation trend chart 320 therein can be displayed, and the position relationship among the respiration variation trend chart 320, the effective reference boundary 322a and the ineffective reference boundary 322b is used for evaluating the ventilation treatment effect in the ventilation treatment time. The ventilation nodes are used to characterize the duration of the ventilation therapy, and in fig. 6, the ventilation nodes may include four, 0 hours, 2 hours, 8 hours, and 20 hours, respectively. The breathing variation trend chart 320 may be generated by: obtaining parameter values of blood oxygen saturation and respiratory rate of a patient at the beginning of timing (0 h), forming a time mark 324 of 0 hour on a two-dimensional parameter coordinate system according to the parameter values of blood oxygen saturation and respiratory rate of 0 hour, waiting for ventilation treatment time to reach 2 hours, and forming a time mark 324 of 324,8 hours and a time mark 324 of 20 hours on the two-dimensional parameter coordinate system according to the parameter values of blood oxygen saturation and respiratory rate of 2 hours, namely, the generation mode of the respiratory variation trend graph 320 is similar to a point drawing method, and each ventilation node carries out point drawing on the two-dimensional parameter coordinate system. In the present embodiment, the shape of the time stamp 324 is not limited, and may be dot-shaped as shown in fig. 6 or cross-shaped as shown in fig. 7 to 9. In some embodiments, the parameter value of the oxygenation respiration index corresponding to each ventilation node may be obtained according to the obtained blood oxygen parameter and respiration parameter of the patient, and then, in combination with the parameter value of the constant parameter set for the two-dimensional parameter coordinate system, for example, in the case that the ventilation treatment time reaches 2 hours, the parameter value of the ROX index at 2 hours is calculated according to the blood oxygen saturation of the patient at 2 hours, the respiration rate and the set inhalation oxygen concentration (at this time, the actual inhalation oxygen concentration may not be obtained, but the set inhalation oxygen concentration may be substituted into the calculation formula to obtain the parameter value of the ROX index in hundred percent), and then, the parameter value of the ROX index is displayed near the time mark 324 of 2 hours, so as to display the ROX index in a numerical form. In addition, a "time attribute" may be added to the respiratory variation trend chart 320, and specifically, the ventilation treatment time corresponding to the time stamp 324 may be displayed near the time stamp 324, for example, "8 hours" may be displayed near the time stamp 324 where the ventilation node is 8 hours. From the whole ventilation treatment process, each ventilation node divides the ventilation treatment into a plurality of treatment intervals, namely a first treatment interval of 0 to 2 hours, a second treatment interval of 2 to 8 hours, and a third treatment interval of 12 to 20 hours, and the user can pay more attention to the treatment effect after passing through one treatment interval clinically, so that the duration of the treatment interval corresponding to the time mark 324 can be displayed near the time mark 324, for example, as shown in fig. 6, the duration "6h" of the second treatment interval can be displayed above the time mark 324 with the ventilation node being 8 hours, which indicates that the time mark 324 corresponds to the ventilation treatment of the second treatment interval, and in the respiratory variation trend chart 320, the duration near the time mark 324 is the duration of the time mark 324 to the treatment interval. In addition, the time markers 324 may be connected according to the sequence of the generation, and the connection may have an arrow pointing from the previous time marker 324 to the next time marker 324, so that the breathing change trend chart 320 is similar to a line chart, and the user may also know the direction of the change of the breathing change trend chart 320, and in summary, may know the ventilation treatment time corresponding to each time marker 324 or the generation sequence of the time markers 324.

Different treatment intervals may correspond to different oxygenation respiration rate thresholds, that is, there may be multiple oxygenation respiration rate thresholds. For example, in the case that there are a plurality of ROX valid thresholds and ROX invalid thresholds, the above parameter coordinate system may correspondingly adjust the positions of the reference boundaries, specifically refer to the embodiment shown in fig. 7 to 12, where the ROX valid thresholds include a first ROX valid threshold and a second ROX valid threshold, and the ROX invalid thresholds include a first ROX valid threshold, a second ROX invalid threshold and a third ROX invalid threshold (or may also be considered to have a third ROX valid threshold, and the third ROX valid threshold and the third invalid threshold are equal), as shown in fig. 7 and 10, where the parameter value of the ROX index on the valid reference boundary 322a is equal to the first ROX valid threshold, and the parameter value of the ROX index on the invalid reference boundary 322b is equal to the first ROX valid threshold, where the first ROX valid threshold is 3.85, and the first ROX invalid threshold is 2.85; as shown in fig. 8 and 11, which may represent a graph 320 of the trend of respiratory change after a ventilation treatment time of 8 hours (6 h in the graph represents that ventilation was continued for 6h since the last ventilation node), the parameter value of the ROX index on the effective reference boundary 322a is equal to a second ROX effective threshold, and the parameter value of the ROX index on the ineffective reference boundary 322b is equal to a second ROX ineffective threshold, wherein the second ROX effective threshold is 4.88 and the second ROX ineffective threshold is 3.85; as shown in fig. 9 and 12, which show a graph 320 of the trend of respiratory change after a ventilation treatment time of 20 hours (12 hours in the figure indicates that the treatment was continued for 12 hours since the last ventilation node), the parameter value of the ROX index on the invalid reference boundary 322b in the figure is equal to a third ROX invalid threshold, wherein the third ROX invalid threshold is 4.88.

In some embodiments, step S400c may also be performed directly after step S200, i.e., the breathing trend graph 320 is directly generated without generating the oxygenation respiration index.

In some embodiments, step S300 is followed by:

and step S400d, comparing the parameter value of the oxygenation respiration index with the oxygenation respiration index threshold value, and outputting prompt information according to the comparison result.

The prompting information may be evaluation information, such as whether ventilation therapy is effective, whether ventilation therapy is ineffective or other evaluation information, alarm information, such as prompting patient vital sign abnormality, or operation guiding information, such as prompting a user to keep current ventilation therapy or change ventilation mode. The comparison between the parameter value of the oxygenation respiration index and the oxygenation respiration index threshold value may be either real-time comparison or intermittent comparison, for example, when the ventilation treatment time reaches a preset time, the parameter value of the oxygenation respiration index at the preset time is compared with the oxygenation respiration index threshold value, and prompt information is output according to the comparison result. The following continues to describe how to output the hint information using the ROX index in HFNC as an example.

Specifically, in a certain actual clinical treatment, when a patient is receiving nasal high flow rate oxygen therapy and a physiological parameter meets the precondition that 200mmHg is less than or equal to PaO2/FiO2 (or SpO2/FiO 2) < 300mmHg, the nasal high flow rate oxygen therapy flow rate is 40-50L/min, fiO2 is 100%, the ventilation treatment time is continuously observed for 2 hours, namely the length of ventilation treatment time is 2 hours, the first ROX effective threshold value after 2 hours of nasal high flow rate oxygen therapy is simultaneously set to be 3.85, the first ROX ineffective threshold value is 2.85, after nasal high flow rate oxygen therapy lasts for two hours, the parameter value of ROX index is respectively compared with the first ROX effective threshold value and the second ROX ineffective threshold value, when the ROX index is more than or equal to 3.85, the evaluation result is that the current nasal high flow rate oxygen therapy effect is better, and the corresponding prompt information can be 'hold HFNC'; when the ROX index is less than 2.85, the evaluation result is that the current nasal high flow rate oxygen therapy has poor curative effect, and the corresponding prompt message can be 'stop HFNC'; when the ROX index is 2.85 or more and less than 3.85, the evaluation result shows that the nasal high flow rate oxygen therapy treatment effect for the current 2 hours is general, and the corresponding prompt information can be' keep HFNC and observe for 6 hours.

In some embodiments, the parameter value of the blood oxygen parameter and the blood oxygen parameter threshold value are compared, and the parameter value of the respiratory parameter and the respiratory parameter threshold value are compared, so that the ventilation treatment effect is evaluated, and corresponding prompt information can be output, wherein the blood oxygen parameter reference value and the respiratory parameter reference value can be stored by default or input by a user operation. The user may input an operation by touching the display screen directly or by an external input device (keyboard, mouse, or wheel).

The above steps S400a, S400b, S400c and S400d may be combined, i.e., one or more of the above steps may be performed after the step S300 is performed.

Those skilled in the art will appreciate that all or part of the functions of the various methods in the above embodiments may be implemented by hardware, or may be implemented by a computer program. When all or part of the functions in the above embodiments are implemented by means of a computer program, the program may be stored in a computer readable storage medium, and the storage medium may include: read-only memory, random access memory, magnetic disk, optical disk, hard disk, etc., and the program is executed by a computer to realize the above-mentioned functions. For example, the program is stored in the memory of the device, and when the program in the memory is executed by the processor, all or part of the functions described above can be realized. In addition, when all or part of the functions in the above embodiments are implemented by means of a computer program, the program may be stored in a storage medium such as a server, another computer, a magnetic disk, an optical disk, a flash disk, or a removable hard disk, and the program in the above embodiments may be implemented by downloading or copying the program into a memory of a local device or updating a version of a system of the local device, and when the program in the memory is executed by a processor.

The foregoing description of the invention has been presented for purposes of illustration and description, and is not intended to be limiting. Variations of the above embodiments may be made by those of ordinary skill in the art in light of the present teachings.

Claims

A medical device system, comprising:

a parameter acquisition device for acquiring blood oxygen parameters and respiratory parameters of a patient;

the system comprises one or more processors, a timing module and a timing module, wherein the one or more processors are used for starting timing of ventilation treatment of a patient when the timing condition is detected to be met, obtaining ventilation treatment time according to the timing, generating an oxygenation respiration index corresponding to the ventilation treatment time according to the blood oxygen parameter and the respiration parameter, evaluating ventilation treatment effect in the ventilation treatment time corresponding to the oxygenation respiration index, and generating an oxygenation respiration index trend graph and/or an oxygenation respiration index trend table, wherein the oxygenation respiration index trend graph and/or the oxygenation respiration index trend table change with time according to the oxygenation respiration index and the ventilation treatment time corresponding to the oxygenation respiration index;

and the display device is used for displaying the oxygenation respiration index trend chart and/or the oxygenation respiration index trend table.
The medical device system of claim 1, wherein the processor is further configured to:

Generating a blood oxygen parameter trend chart and/or a blood oxygen parameter trend table of the blood oxygen parameters changing along with time according to the blood oxygen parameters in the ventilation treatment time; and/or

Generating a breathing parameter trend chart and/or a breathing parameter trend table of the breathing parameter changing along with time according to the breathing parameter in the ventilation treatment time;

the display device is also used for displaying the blood oxygen parameter trend graph and/or the blood oxygen parameter trend table; and/or

The display device is also used for displaying the breathing parameter trend graph and/or the breathing parameter trend table.
The medical device system of claim 2, wherein the processor is further configured to:

marking at least one of the blood oxygen parameter trend graph and the respiratory parameter trend graph and a part of the oxygenation respiration index trend graph at the same time respectively;

when a mark change position instruction input by a user for at least one of the blood oxygen parameter trend chart and the respiratory parameter trend chart or the oxygenation respiration index trend chart is detected, synchronously changing the at least one of the blood oxygen parameter trend chart and the respiratory parameter trend chart and the position of a mark on the oxygenation index trend chart;

Outputting a parameter value of the oxygenation respiration index at the moment corresponding to the marked position on the oxygenation respiration index trend chart;

outputting the parameter value of the blood oxygen parameter at the moment corresponding to the marked position on the blood oxygen parameter trend chart and/or outputting the parameter value of the respiratory parameter at the moment corresponding to the marked position on the respiratory parameter trend chart.
The medical device system of any one of claims 1-3, wherein the oxygenation-respiration index trend graph comprises a line graph, a bar graph, or a graph.
The medical device system of any one of claims 1-4, wherein the oxygenation respiration index trend graph comprises a trend waveform of the oxygenation respiration index over time, the processor further configured to:

setting at least one oxygenation respiration index threshold, wherein the magnitude relation between the parameter value of the oxygenation respiration index and the oxygenation respiration index threshold is used for indicating the ventilation treatment effect; dividing the oxygenation respiration index trend map into at least two first areas extending along a time axis by taking the oxygenation respiration index threshold as a boundary according to the at least one oxygenation respiration index threshold;

The at least two first regions are marked differently on the oxygenation-respiration index trend map, respectively, or trend waveforms located in the different first regions are displayed differently, respectively.
The medical device system of claim 5, wherein setting at least one oxygenation-respiratory-index threshold comprises:

based on the setting instruction input by the user, a setting window allowing the user to set the oxygenation respiration index threshold for different time periods respectively is popped up.
The medical device system of claim 6, wherein the processor is further configured to:

and acquiring a new oxygenation respiration index threshold set by a user, and updating a first area divided on the oxygenation respiration index trend chart according to the new oxygenation respiration index threshold.
The medical device system of claim 5, wherein the at least two first regions are marked differently on the oxygenation-respiratory index trend chart, respectively, comprising at least one of:

filling the at least two first regions with different colors or patterns on the oxygenation-respiration index trend map;

displaying boundary lines between adjacent first areas, wherein the parameter value of the oxygenation respiration index on each boundary line is correspondingly equal to each oxygenation respiration index threshold value;

The displaying trend waveforms in different first areas in different ways includes:

the trend waveforms in the different first areas are displayed in different colors, brightness or lines.
The medical device system of claim 8, wherein different ones of the boundary line graphic attributes differ, the graphic attributes including at least one of color, thickness, and line type.
The medical device system of claim 1, wherein the oxygenation respiration index trend table comprises parameter values of oxygenation respiration indexes corresponding to at least two points in time during the ventilation therapy time, the processor further configured to:

setting at least one oxygenation respiration index threshold, wherein the magnitude relation between the parameter value of the oxygenation respiration index and the oxygenation respiration index threshold is used for indicating the ventilation treatment effect;

determining at least two threshold ranges from the at least one oxygenated breath index threshold;

determining a threshold range within which each parameter value of the oxygenation respiration index falls in the oxygenation respiration index trend table, and displaying the parameter values of the oxygenation respiration indexes falling in different threshold ranges in different manners.
The medical device system of claim 1, wherein the processor is further configured to:

Determining a historical moment selected by a user based on a moment selection instruction input by the user on the oxygenation respiration index trend graph;

and outputting a parameter value of the oxygenation respiration index corresponding to the history time according to the selected history time.
The medical device system of claim 11, wherein the processor is further configured to: and outputting the parameter value of the blood oxygen parameter and/or the parameter value of the respiratory parameter corresponding to the history time according to the selected history time.
The medical device system according to any one of claims 1 to 12, wherein the medical device system is a plurality of medical devices, at least one of the plurality of medical devices having the parameter acquisition means for transmitting the acquired blood oxygen parameter and the respiratory parameter to another medical device.
The medical device system of claim 1, wherein the processor is further configured to:

setting at least one oxygenation respiration index threshold;

when the ventilation treatment time reaches a preset time, comparing the parameter value of the oxygenation respiration index at the preset time with an oxygenation respiration index threshold corresponding to the preset time, and outputting prompt information according to a comparison result.
A medical device system, comprising:

the parameter acquisition device is used for acquiring blood oxygen parameters and respiratory parameters of a patient, wherein the blood oxygen parameters and the respiratory parameters comprise at least one type of parameters, and the blood oxygen parameters and the respiratory parameters are used for obtaining an oxygenation respiratory index according to a preset calculation method;

one or more processors configured to:

setting at least two types of parameters of the blood oxygen parameter and the respiratory parameter as coordinate parameters and establishing a parameter coordinate system, wherein one coordinate axis of the parameter coordinate system corresponds to one coordinate parameter; setting at least one oxygenation respiration index threshold value, and generating a reference boundary corresponding to the oxygenation respiration index threshold value in the parameter coordinate system;

when the timing condition is detected to be met, starting timing the ventilation treatment of the patient, obtaining ventilation treatment time according to the timing, generating a breathing variation trend graph of the coordinate parameter changing along with time in the parameter coordinate system according to parameter values of the coordinate parameter corresponding to a plurality of ventilation nodes in the ventilation treatment time, wherein the ventilation nodes are used for representing the duration of the ventilation treatment, and the position relation between the breathing variation trend graph and the reference boundary is used for evaluating the ventilation treatment effect in the ventilation treatment time;

And the display device is used for displaying the parameter coordinate system and the breathing variation trend graph.
The medical device system of claim 15, wherein generating the respiration variability trend graph comprises:

and forming a time mark corresponding to each ventilation node on the parameter coordinate system according to the parameter value of the coordinate parameter corresponding to each ventilation node.
The medical device system of claim 16, wherein the processor is further configured to calculate a parameter value of the oxygenation respiratory index corresponding to each of the ventilation nodes based on the parameter value of the blood oxygenation parameter and the parameter value of the respiration parameter corresponding to each of the ventilation nodes, and wherein the display device is further configured to display a time stamp corresponding to each of the ventilation nodes simultaneously with the parameter value of the oxygenation respiratory index; and/or

Each time one of the time stamps is formed, the processor generates a connection line having a direction stamp between the last time stamp and the most recently formed time stamp, the direction stamp being used to point from the last time stamp to the next time stamp.
The medical device system of any one of claims 15 to 17, wherein the parameter coordinate system is a two-dimensional coordinate system or a three-dimensional coordinate system, the blood oxygen parameter and the respiratory parameter both include a number of parameter types greater than a dimension of the parameter coordinate system, the generating a reference boundary within the parameter coordinate system corresponding to the oxygenation respiration index threshold comprises:

Setting the blood oxygen parameter and the respiratory parameter, which are not the coordinate parameters, as constant parameters;

setting a parameter value of the constant parameter;

generating a reference boundary corresponding to the oxygenation respiration index threshold value in the parameter coordinate system according to the set oxygenation respiration index threshold value, the set coordinate parameters, the set parameter values of the constant parameters and the preset calculation method.
The medical device system of claim 18, wherein the constant parameter has a plurality of parameter values, one oxygenated breath index threshold has a corresponding at least one reference boundary, and one oxygenated breath index threshold corresponds to at least one reference boundary generated based on different parameter values of the constant parameter.
The medical device system of any one of claims 15 to 17, wherein the parameter coordinate system is a two-dimensional coordinate system or a three-dimensional coordinate system, the blood oxygen parameter and the respiratory parameter both include a number of parameter types equal to a dimension of the parameter coordinate system, the generating a reference boundary within the parameter coordinate system corresponding to the oxygenation respiration index threshold comprises:

And generating a reference boundary corresponding to the oxygenation respiration index threshold value in the parameter coordinate system according to the set at least one oxygenation respiration index threshold value, the set coordinate parameters and the preset calculation method.
The medical device system of claim 16 or 18, wherein one oxygenated breath index threshold has a corresponding one of the reference boundaries, the processor further configured to divide the parameter coordinate system into at least two second regions based on at least one of the reference boundaries;

the display device is further adapted to mark the at least two second areas in different ways, respectively.
The medical device system of claim 21, wherein setting at least one oxygenation-respiratory-index threshold comprises:

based on the setting instruction input by the user, a setting window allowing the user to set the oxygenation respiration index threshold for different time periods respectively is popped up.
The medical device system of claim 22, wherein the processor is further configured to:

acquiring a new oxygenation respiration index threshold set by a user, and updating a second area divided on the parameter coordinate system according to the new oxygenation respiration index threshold; and in the process of forming the time mark, determining the display mode of the time mark according to the relation between the position of the time mark and the different second areas.
The medical device system of claim 16 or 18, wherein an oxygenated breath index threshold has a corresponding reference boundary, said processor further configured to:

setting a plurality of coordinate parameter thresholds, wherein one oxygenation respiration index threshold corresponds to at least one coordinate parameter threshold;

dividing the parameter coordinate system into at least two second areas according to at least one reference boundary;

dividing the parameter coordinate system into at least two third areas with the coordinate parameter thresholds as boundaries according to at least one coordinate parameter threshold corresponding to each oxygenation respiration index threshold, wherein one third area corresponds to one second area;

combining each second region with a corresponding third region to obtain at least two composite regions;

the display device is further configured to mark the at least two composite regions in different ways on the parameter coordinate system, respectively.
The medical device system of claim 24, wherein setting at least one oxygenation-respiratory-index threshold and a plurality of coordinate-parameter thresholds comprises:

based on the setting instruction input by the user, a setting window allowing the user to set the oxygenation respiration index threshold value for different time periods respectively and corresponding to at least one coordinate parameter threshold value is popped up.
The medical device system of claim 25, wherein the processor is further configured to:

acquiring a new oxygenation respiration index threshold set by a user, and updating a second area divided on the parameter coordinate system according to the new oxygenation respiration index threshold;

acquiring a new coordinate parameter threshold set by a user, and updating a third area divided on the parameter coordinate system according to the new coordinate parameter threshold;

updating the at least two composite regions according to the second region and the third region updated on the parameter coordinate system;

and in the process of forming the time mark, determining the display mode of the time mark according to the relation between the position of the time mark and different composite areas.
The medical device system of any one of claims 18-26, wherein the reference boundary is a reference line when the parameter coordinate system is a two-dimensional coordinate system and a reference plane when the parameter coordinate system is a three-dimensional coordinate system.
A medical device system, comprising:

a parameter acquisition device for acquiring blood oxygen parameters and respiratory parameters of a patient;

the one or more processors are used for starting timing the ventilation treatment of the patient when the timing condition is detected to be met, obtaining ventilation treatment time according to the timing, generating an oxygenation respiration index corresponding to the ventilation treatment time according to the blood oxygen parameter and the respiration parameter, wherein the oxygenation respiration index is used for evaluating the ventilation treatment effect in the ventilation treatment time corresponding to the oxygenation respiration index, comparing the parameter value of the oxygenation respiration index with an oxygenation respiration index threshold value, and outputting prompt information according to the comparison result;

And the display device is used for displaying the prompt information.
The medical device system of claim 28, wherein comparing the parameter value of the oxygenation respiration index with an oxygenation respiration index threshold value, outputting a prompt message based on the comparison result, comprises:

when the ventilation treatment time reaches a preset time, comparing the parameter value of the oxygenation respiration index at the preset time with the oxygenation respiration index threshold value, and outputting prompt information according to a comparison result.
The medical device system of claim 28 or 29, wherein the outputting the prompt message based on the comparison result comprises at least one of:

outputting alarm information according to the comparison result;

outputting evaluation information of the ventilation treatment effect according to the comparison result;

and outputting operation guidance for ventilation treatment according to the comparison result.
The medical device system of claim 28 or 29, wherein the means for outputting the alert information comprises at least one of text, sound, color, light, flashing.
A medical device system, comprising:

a parameter acquisition device for acquiring blood oxygen parameters and respiratory parameters of a patient;

And the one or more processors are used for timing the ventilation treatment of the patient when the timing condition is detected to be met, obtaining ventilation treatment time according to the timing, generating an oxygenation respiratory index corresponding to the ventilation treatment time according to the blood oxygen parameter and the respiratory parameter, wherein the oxygenation respiratory index is used for evaluating the ventilation treatment effect in the ventilation treatment time corresponding to the oxygenation respiratory index and outputting a real-time parameter value of the oxygenation respiratory index.
The medical device system of claim 32, wherein the processor is further configured to:

outputting the real-time parameter value of the oxygenation respiration and outputting the real-time parameter value of the blood oxygenation parameter and/or the respiration parameter.
A medical device system, comprising:

parameter acquisition means for acquiring a blood oxygen parameter and a respiratory parameter of a patient, each of the blood oxygen parameter and the respiratory parameter including at least one type of parameter;

and the one or more processors are used for timing the ventilation treatment of the patient when the timing condition is detected to be met, obtaining ventilation treatment time according to the timing, and generating an oxygenation respiratory index corresponding to the ventilation treatment time according to the blood oxygen parameter and the respiratory parameter, wherein the oxygenation respiratory index is used for evaluating the ventilation treatment effect in the ventilation treatment time corresponding to the oxygenation respiratory index.
The medical device system of claim 34, wherein the processor is further configured to perform at least two of the following methods:

generating an oxygenation respiration index trend chart and/or an oxygenation respiration index trend table of the oxygenation respiration index changing with time;

setting at least two types of parameters of the blood oxygen parameter and the respiratory parameter as coordinate parameters and establishing a parameter coordinate system, wherein one coordinate axis of the parameter coordinate system corresponds to one coordinate parameter; setting at least one oxygenation respiration index threshold value, and generating a reference boundary corresponding to the oxygenation respiration index threshold value in the parameter coordinate system; generating a breathing change trend graph of the coordinate parameters along with time change in the parameter coordinate system according to parameter values of the coordinate parameters corresponding to a plurality of breathing nodes in the breathing treatment time, wherein the breathing nodes are used for representing duration of the breathing treatment, and the position relation between the breathing change trend graph and the reference boundary is used for evaluating the breathing treatment effect in the breathing treatment time;

comparing the parameter value of the oxygenation respiration index with an oxygenation respiration index threshold value, and outputting prompt information according to a comparison result; and

Outputting the real-time parameter value of the oxygenation respiration index.
The medical device system of claim 1, 15, 28, 32, or 34, wherein the medical device in the medical device system comprises a ventilator, an anesthesia machine, an oxygen therapy instrument, a monitor, a central station, a medical information system, or a medical mobile terminal.
The medical device system of claim 1, 15, 28, 32, or 34, wherein the parameter acquisition means comprises:

at least one sensor, at least one of the blood oxygen parameter and the respiratory parameter being acquired by the sensor in real time; and/or

And the communication equipment is used for receiving the blood oxygen parameter and the breathing parameter of the patient which are sent externally.
The medical device system of claim 1, 15, 28, 32, or 34, wherein the ventilation therapy comprises oxygen therapy or ventilation.
The medical device system of claim 1, 15, 28, 32, or 34, wherein the blood oxygen parameter comprises at least one of percutaneous blood oxygen saturation, arterial blood oxygen partial pressure, and arterial blood oxygen saturation, the respiratory parameter comprises at least one of an inhalation oxygen partial pressure, and a respiratory rate, and the oxygenation respiratory index comprises at least one of a ROX index, an oxygenation index, an oxygen index, and a pulse oxygen saturation index.
The medical device system of claim 1, 15, 28, 32 or 34, wherein the parameter acquisition means is further for acquiring a heart rate and/or pulse rate of the patient;

the processor is further configured to:

an evaluation parameter for evaluating the effectiveness of the ventilation therapy is obtained based on the oxygenation respiration index and at least one of the heart rate and the pulse rate of the patient.
The medical device system of claim 1, 15, 28, 32, or 34, wherein the detecting that the timing condition is met begins timing ventilation therapy of the patient, comprising at least one of:

when the processor detects that the blood oxygen parameter and/or the respiratory parameter of the patient meet the preset conditions, starting timing;

starting timing when the processor receives a timing instruction;

the processor is configured to begin timing when it detects initiation of ventilation therapy to the patient.
The medical device system of claim 1, 15, 28, 32, or 34, wherein the ventilation therapy is a non-invasive ventilation therapy.
The medical device system of claim 1, 15, 28, 32, or 34, wherein the ventilation therapy is high flow rate oxygen therapy.
A monitoring device, comprising:

At least one sensor for monitoring at least one physiological parameter of the patient, the at least one physiological parameter comprising a blood oxygen parameter and a respiratory parameter;

the display device is used for displaying a monitoring interface, and part or all of the physiological parameters are displayed on the monitoring interface;

and when the processor detects that the parameter value of the oxygenation respiration index is lower than a preset lower limit value, controlling the display device to switch the monitoring interface into an oxygenation prompting interface, and displaying at least the real-time parameter value of the oxygenation respiration index and an oxygenation respiration index trend chart, wherein the oxygenation respiration index trend chart is generated by the processor according to the oxygenation respiration index in the ventilation treatment time and is used for representing the change of the oxygenation respiration index along with time.
The apparatus of claim 44, wherein in displaying the oxygenation respiration index on a monitoring interface, the processor is further configured to:

and when the ventilation treatment time is at a preset time, comparing the oxygenation respiration index with an oxygenation respiration index threshold corresponding to the preset time, and outputting prompt information according to a comparison result.
The apparatus of claim 45, wherein the outputting the prompt message based on the comparison result comprises at least one of:

outputting alarm information according to the comparison result;

outputting evaluation information of the ventilation treatment effect according to the comparison result;

and outputting operation guidance for ventilation treatment according to the comparison result.
A respiratory support apparatus, comprising:

a patient interface for connecting to a respiratory system of a patient;

a respiratory assistance device for providing respiratory support power in ventilation therapy to ventilate a patient;

at least one sensor for monitoring at least one physiological parameter of the patient, the at least one physiological parameter comprising a blood oxygen parameter and a respiratory parameter;

a display device for displaying a ventilation interface having displayed thereon some or all of the at least one physiological parameter;

And when the processor detects that the parameter value of the oxygenation respiration index is lower than a preset lower limit value, controlling the display device to switch the ventilation interface into an oxygenation prompting interface, and displaying at least the real-time parameter value of the oxygenation respiration index and an oxygenation respiration index trend chart, wherein the oxygenation respiration index trend chart is generated by the processor according to the oxygenation respiration index in the ventilation treatment time and is used for representing the change of the oxygenation respiration index along with time.
The apparatus of claim 47, wherein in displaying the oxygenation respiration index on a ventilation interface, the processor is further configured to:

and when the ventilation treatment time is at a preset time, comparing the oxygenation respiration index with an oxygenation respiration index threshold corresponding to the preset time, and outputting prompt information according to a comparison result.
The apparatus of claim 48, wherein the outputting the hint information based on the comparison result includes at least one of:

outputting alarm information according to the comparison result;

outputting evaluation information of the ventilation treatment effect according to the comparison result;

and outputting operation guidance for ventilation treatment of the patient according to the comparison result.
A medical device system, comprising:

a respiratory support apparatus for performing ventilation therapy for a patient;

a monitoring device for monitoring vital signs of a patient;

and at least one device of the respiratory support device and the monitoring device is used for timing the ventilation treatment of the patient when the timing condition is detected to be met, obtaining ventilation treatment time according to the timing, collecting blood oxygen parameters and respiratory parameters of the patient, and generating an oxygenation respiratory index corresponding to the ventilation treatment time according to the blood oxygen parameters and the respiratory parameters, wherein the oxygenation respiratory index is used for evaluating the ventilation treatment effect in the ventilation treatment time corresponding to the oxygenation respiratory index.
A method of processing parameters of a medical device system, comprising:

when the condition of timing is detected to be met, starting timing the ventilation treatment of the patient, and obtaining ventilation treatment time according to the timing;

Obtaining blood oxygen parameters and respiratory parameters of a patient, and generating an oxygenation respiratory index corresponding to ventilation treatment time according to the blood oxygen parameters and the respiratory parameters, wherein the oxygenation respiratory index is used for evaluating ventilation treatment effect in the ventilation treatment time corresponding to the oxygenation respiratory index;

generating and displaying an oxygenation respiration index trend chart and/or an oxygenation respiration index trend table of the oxygenation respiration index changing along with time according to the oxygenation respiration index and the corresponding ventilation treatment time.
A method of processing parameters of a medical device system, comprising:

when the condition of timing is detected to be met, starting timing the ventilation treatment of the patient, and obtaining ventilation treatment time according to the timing;

obtaining blood oxygen parameters and respiratory parameters of a patient, wherein the blood oxygen parameters and the respiratory parameters comprise at least one type of parameters, and the blood oxygen parameters and the respiratory parameters are used for obtaining an oxygenation respiratory index according to a preset calculation method;

setting at least two types of parameters of the blood oxygen parameter and the respiratory parameter as coordinate parameters and establishing a parameter coordinate system, wherein one coordinate axis of the parameter coordinate system corresponds to one coordinate parameter; setting at least one oxygenation respiration index threshold value, and generating a reference boundary corresponding to the oxygenation respiration index threshold value in the parameter coordinate system;

Generating and displaying a breathing change trend graph of the coordinate parameters along with time change in the parameter coordinate system according to the parameter values of the coordinate parameters corresponding to the plurality of breathing nodes in the breathing treatment time, wherein the breathing nodes are used for representing the duration of the breathing treatment, and the position relationship between the breathing change trend graph and the reference boundary is used for evaluating the breathing treatment effect in the breathing treatment time.
A method of processing parameters of a medical device system, comprising:

when the condition of timing is detected to be met, starting timing the ventilation treatment of the patient, and obtaining ventilation treatment time according to the timing;

obtaining blood oxygen parameters and respiratory parameters of a patient, and generating an oxygenation respiratory index corresponding to ventilation treatment time according to the blood oxygen parameters and the respiratory parameters, wherein the oxygenation respiratory index is used for evaluating ventilation treatment effect in the ventilation treatment time corresponding to the oxygenation respiratory index;

and comparing the parameter value of the oxygenation respiration index with an oxygenation respiration index threshold value, and outputting prompt information according to a comparison result.
A method of processing parameters of a medical device system, comprising:

when the condition of timing is detected to be met, starting timing the ventilation treatment of the patient, and obtaining ventilation treatment time according to the timing;

Obtaining blood oxygen parameters and respiratory parameters of a patient, and generating an oxygenation respiratory index corresponding to ventilation treatment time according to the blood oxygen parameters and the respiratory parameters, wherein the oxygenation respiratory index is used for evaluating ventilation treatment effect in the ventilation treatment time corresponding to the oxygenation respiratory index;

outputting the real-time parameter value of the oxygenation respiration index.
A method of processing parameters of a medical device system, comprising:

when the condition of timing is detected to be met, starting timing the ventilation treatment of the patient, and obtaining ventilation treatment time according to the timing;

and obtaining blood oxygen parameters and respiratory parameters of the patient, and generating an oxygenation respiratory index corresponding to the ventilation treatment time according to the blood oxygen parameters and the respiratory parameters, wherein the oxygenation respiratory index is used for evaluating the ventilation treatment effect in the ventilation treatment time corresponding to the oxygenation respiratory index.
A computer readable storage medium having stored thereon a program executable by a processor to implement the method of any of claims 51 to 55.