WO2022099337A1 - Dispositif portable pour générer une pression variable à une extrémité - Google Patents

Dispositif portable pour générer une pression variable à une extrémité Download PDF

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Publication number
WO2022099337A1
WO2022099337A1 PCT/AT2021/060420 AT2021060420W WO2022099337A1 WO 2022099337 A1 WO2022099337 A1 WO 2022099337A1 AT 2021060420 W AT2021060420 W AT 2021060420W WO 2022099337 A1 WO2022099337 A1 WO 2022099337A1
Authority
WO
WIPO (PCT)
Prior art keywords
pressure
extremity
piston
housing
actuator
Prior art date
Application number
PCT/AT2021/060420
Other languages
German (de)
English (en)
Inventor
Jürgen FORTIN
Original Assignee
Cnsystems Medizintechnik Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cnsystems Medizintechnik Gmbh filed Critical Cnsystems Medizintechnik Gmbh
Publication of WO2022099337A1 publication Critical patent/WO2022099337A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A61B5/022—Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers
    • A61B5/02233—Occluders specially adapted therefor
    • A61B5/02241—Occluders specially adapted therefor of small dimensions, e.g. adapted to fingers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A61B5/02141—Details of apparatus construction, e.g. pump units or housings therefor, cuff pressurising systems, arrangements of fluid conduits or circuits
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A61B5/022—Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers
    • A61B5/0225—Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers the pressure being controlled by electric signals, e.g. derived from Korotkoff sounds
    • A61B5/02255—Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers the pressure being controlled by electric signals, e.g. derived from Korotkoff sounds the pressure being controlled by plethysmographic signals, e.g. derived from optical sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/024—Detecting, measuring or recording pulse rate or heart rate
    • A61B5/02416—Detecting, measuring or recording pulse rate or heart rate using photoplethysmograph signals, e.g. generated by infrared radiation
    • A61B5/02422—Detecting, measuring or recording pulse rate or heart rate using photoplethysmograph signals, e.g. generated by infrared radiation within occluders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813—Specially adapted to be attached to a specific body part
    • A61B5/6825—Hand
    • A61B5/6826—Finger
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16H—GEARING
    • F16H57/00—General details of gearing
    • F16H57/04—Features relating to lubrication or cooling or heating
    • F16H57/048—Type of gearings to be lubricated, cooled or heated
    • F16H57/0497—Screw mechanisms
    • H—ELECTRICITY
    • H02—GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
    • H02K—DYNAMO-ELECTRIC MACHINES
    • H02K7/00—Arrangements for handling mechanical energy structurally associated with dynamo-electric machines, e.g. structural association with mechanical driving motors or auxiliary dynamo-electric machines
    • H02K7/06—Means for converting reciprocating motion into rotary motion or vice versa
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0247—Pressure sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • A61B5/14552—Details of sensors specially adapted therefor
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16H—GEARING
    • F16H25/00—Gearings comprising primarily only cams, cam-followers and screw-and-nut mechanisms
    • F16H25/18—Gearings comprising primarily only cams, cam-followers and screw-and-nut mechanisms for conveying or interconverting oscillating or reciprocating motions
    • F16H25/20—Screw mechanisms
    • F16H2025/2062—Arrangements for driving the actuator
    • F16H2025/209—Arrangements for driving the actuator using worm gears

Definitions

  • the invention relates to a portable device suitable for generating a variable pressure on an extremity containing an artery, with a housing or housing part which can be attached to the extremity and is suitable for at least partially enclosing the extremity, and with a housing supporting, limb-acting, flexible bladder filled with a fluid.
  • the main application of the device is to measure blood pressure on the finger of one hand.
  • cardiovascular parameters including blood pressure, cardiac output, vascular resistance and medical parameters for the assessment of the autonomic nervous system is possible with the help of stationary measuring systems.
  • the basis for calculating these parameters is continuous recording of the blood pressure signal.
  • the Vascular Unloading Technique requires a pressure generation system that can fully follow the continuous blood pressure. This means that pressure changes of more than 1500 mmHg/sec must be achieved with an upper frequency limit of around 40 Hz.
  • EP 1 179 991 B1 shows such a pressure generation system with the help of separate inlet and outlet valves. In addition to these inlet and outlet valves, an air pressure pump, an air reservoir and numerous electronic components are required for the pressure generation system, which make use in a portable system difficult or impossible.
  • the average power consumption of such a blood pressure module is 2.5W with peak power in the start-up phase of up to 5W. This high energy consumption also makes the use of the Vascular Unloading Technique in a "wearable" at least difficult.
  • EP 2 854 626 B1 now describes a new method and a device that only applies a very slowly changing contact pressure to the extremity (usually fingers) in order to follow the mean arterial blood pressure.
  • WO 2016/110781 A1 describes various measurement modes and additional elements that are advantageous for use as a portable device.
  • a measuring system for the continuous determination of blood pressure has become known from EP 3 419 515 B1, which has the external shape of a computer mouse, on the surface of which a double-finger sensor is designed to record two fingers of one hand.
  • the finger sensors have inflatable cuffs, the pressure of which tracks the intra-arterial blood pressure in the finger with the help of a photoplethysmographic system. This requires real-time controlled valves at the entrance to the cuffs that supply pressure from a compressed air source.
  • the pressure generation system together with the pump and an air reservoir can be arranged in the body of the computer mouse.
  • WO 2020/176214 A1 describes a finger sensor for measuring blood pressure, which has a bladder that can be pressed against the finger with constant pressure and is filled with an incompressible fluid. A pressure sensor is arranged in the bladder, with which the arterial blood pressure can be measured in the finger.
  • the aim of the invention is to further develop a device or an actuator for generating a variable pressure on an extremity containing an artery in such a way that a portable application, in particular as part of a blood pressure measuring device, is made possible easily and inexpensively.
  • the actuator according to the invention is, for example, part of a sphygmomanometer that is attached to an extremity in which at least one artery is located.
  • a finger of the hand is preferably used for this, also the wrist, the temple, as well as in veterinary applications the tail of an animal could be used as a measurement site.
  • the actuator according to the invention which essentially consists of a drive device and an actuating element (e.g. piston, plunger, clamp, etc.) for changing the pressure in the flexible bladder - is suitable for installation in a portable sphygmomanometer
  • the device for Pressure generation can be miniaturized. This means that it can be assembled from just a few small parts.
  • the aim is to integrate the actuator into a finger ring, for example.
  • the energy requirement of the drive for the actuator must be kept small.
  • the goal for the energy requirement is that the "wearable” can measure continuously for 24 hours if possible.
  • the battery required for this must therefore be so small that it can also be integrated into the "wearable”.
  • the actuator serves to generate only small changes in the contact pressure so that the mean arterial blood pressure can be followed. According to the study above, only maximum changes of 30 mmHg/sec are necessary, on average it is only 1.3 mmHg/sec. The maximum contact pressure is 150 mmHg (200 mbar).
  • the actuator is part of a sphygmomanometer, elements are required with which pulsations, i.e. changes in the volume of the extremity for each heartbeat, can be recorded, while at the same time the contact pressure on the extremity can be changed by the actuator.
  • the actuator as part of a blood pressure measuring device must generate a homogeneous contact pressure for the precise detection of the pulsations. This is achieved by suitable geometry of the system. This is essential because it is the only way to ensure high clinical accuracy. If, for example, the transmission or coupling factor for detecting the pulsations over the pressure range were to change, then the pressure-related pulsations would have different amplitudes in different ranges of the contact pressure. However, the detection of the pulsations and their amplitude is essential for an accurate detection of the blood pressure.
  • 1a shows a non-invasive blood pressure measuring device (“wearable”) that can be worn on the finger of one hand, into which the device according to the invention for generating pressure (“actuator”) is integrated;
  • FIG. 1b shows an enlarged view of the wearable according to FIG. 1a;
  • FIG. 2 shows the front view, side view, top view and bottom view of the wearable according to FIG. 1b;
  • FIG. 3 shows a section according to line A-A in FIG. 2 through the wearable with a first embodiment variant of the device for generating pressure
  • FIG. 6 shows a second embodiment variant of the device for generating pressure in a sectional view according to FIG.
  • the present invention describes different embodiment variants of an actuator, as well as a method of how these actuators pass on the pressure to an extremity.
  • These actuators can be used, for example, for portable sphygmomanometers—so-called “wearables”.
  • the actuator generates a pressure that is transmitted to a limb that contains at least one artery.
  • the finger of one hand is used, but applications on other parts of the body are also possible, such as the wrist, the temple, and also the tail of an animal in veterinary applications.
  • the portable blood pressure measuring device 301 is shown in the form of a finger ring including a ring attachment for use on a finger.
  • the corresponding device for generating pressure (or actuator) is integrated into the wearable in order to exert a predeterminable, variable pressure on the finger.
  • FIG. 2 also shows the finger ring in front view, side view, top view and bottom view.
  • FIG. 3 shows a section through the wearable 301, in whose housing 300 the elements of the actuator are located.
  • the actuator is driven by a motor whose stator 302 is mounted on a printed circuit board under the flat surface of the ring cap.
  • the rotor 303 which is rotatably attached to the stator 302 by a spring 304 .
  • a possible variant of this engine is a low-energy, piezoelectric motor for use on electronic printed circuit boards (see eg www.pcbmotor.com).
  • the selected motor should have a high holding torque. This means that rotor 303 of the motor will stop at the desired location without the application of rest energy, even if some back pressure is applied. In the present variant, this high holding torque is generated by the spring 304, which to a certain extent latches the rotor 303 when it is to stop because no more energy is being applied in the stator 302.
  • the rotor 303 is intended to move a piston 307 to apply pressure to the limb.
  • a gear mechanism is installed to convert the rotational movement of the rotor 303 into a linear movement of the piston 307 .
  • the rotor 303 drives a transmission element 305 which in turn drives the rotatable piston 307 via a gear element 306 .
  • the transmission element 305 is fixed directly to the rotor 303, while the piston 307 can move up and down in the direction of the finger. This movement of the piston 307 is made possible by the present gear element 306 .
  • the piston 307 is guided in a cylinder 308 in the housing 300 . Together they form the gear element 306.
  • the gear element 306 can be realized by a simple thread, with the piston 307 being equipped with an external thread and the cylinder 308 with an internal thread.
  • the illustrated thread 306 is only one possible embodiment. It is important that the friction losses are kept as low as possible. Other mechanical or hydraulic transmission elements are also possible.
  • the movement of the rotor 303 now pushes the piston 307 in the direction of the finger.
  • the piston 307 then presses on a bladder 309 filled with an incompressible fluid, for example a liquid or a gel.
  • an incompressible fluid for example a liquid or a gel.
  • the pressure in the liquid is thereby increased and now acts on the finger (not shown in FIG is in the wearable 301.
  • the fluid-filled bladder 309 has a rigid outer wall and a largely flexible inner wall that abuts the extremity (e.g., fingers).
  • the liquid should be incompressible or sufficiently incompressible. This will require all gases to be removed before use.
  • the liquid must be biocompatible for use in medical products.
  • gels or creams are also considered liquids in this context.
  • the piston 307 presses directly onto the liquid.
  • the transmission element 306 must also function as a seal at the same time. The advantage of this is that the liquid can also serve as a lubricant for the gear element 306, which reduces friction overall.
  • the piston 307 presses on the outer wall of the liquid-filled bladder 309, which then has to be made flexible at this point.
  • the bladder 309 can be designed to be replaced after a few uses, making it disposable.
  • the pressure in the liquid-filled bladder 309 is preferably measured using pressure sensor 310 .
  • this pressure sensor 310 can also be used as a sensor for the arterial pulses or pulsatile pressure fluctuations. These pulsatile pressure fluctuations are caused by the blood movements that occur in the arteries depending on the heartbeat.
  • the pressure sensor 310 must have sufficient resolution and be able to detect pressure changes of at least 0.01 mmHg (0.013 mbar) at an upper limit frequency of at least 40 Hz.
  • PPG photoplethysmography
  • the actuator can be used for the so-called “oscillometric detection of blood pressure” (oscillometry), as is the state of the art on the basis of inflatable cuffs in almost all automated sphygmomanometers on the upper arm or wrist.
  • oscillometric detection of blood pressure oscillometry
  • VCT Vascular Control Technique
  • the pressure on the finger generated by the actuator is continuously adjusted to the mean arterial blood pressure.
  • This method is again based on principles known from oscillometry. Therefore, the correct acquisition of the oscillometric signals with the present actuator is essential.
  • the contact pressure of a cuff or also of the flexible bladder on an extremity is continuously increased (see top image of FIG. 4 "Pressure") or reduced in some other applications.
  • the pulsations (middle image of FIG. 4 "Oscillometric Waves OMW”) are recorded which are caused by the blood movements in the artery.
  • the pulsations in the pressure system are usually recorded using a pressure sensor, but other sensors such as PPG sensors, Doppler, radar, etc. can also be used.
  • the envelope of the pulsation signal is then generated from these pulsations by suitable filters and other signal analysis methods (see lower image of FIG. 4 "envelope of the OMW").
  • Figure 5 shows the details of an "oscillometric envelope" (Oscillometric Wave OMW envelope).
  • Oscillometric Wave OMW envelope The maximum of these bell curves occurs when the contact pressure generated by the actuator corresponds exactly to the mean arterial blood pressure.
  • the associated pulsation A (pulse at 115 mmHg) has the highest amplitude and corresponds to the curve shape that also occurs approximately with true arterial blood pressure.
  • the inverted representation in FIG. 5 is correct because this pulse was recorded using the PPG method.
  • systole there is more arterial blood in the finger and the light or PPG signal becomes smaller, while in diastole and therefore less blood in the measuring section, more light energy can radiate through the finger.
  • the pulsations that occur when the contact pressure is above or below the mean blood pressure naturally have a lower amplitude. However, the curve shapes are fundamentally different. If the contact pressure generated by the actuator is less than the average blood pressure, then a broad ("fat") pulse B occurs - (see pulse at 103 mmHg). If, on the other hand, the contact pressure is greater than the average blood pressure, a so-called “sharp pulse” C - (see pulse at 141 mmHg) occurs.
  • the system shown in FIG. 3 includes a flexible, fluid-filled bladder 309 that completely encloses the finger.
  • the PPG system must be mounted on the flexible inner wall of the bladder 309 here.
  • FIG. 6 now shows a further embodiment variant of the wearable 601 in which a liquid-filled bladder 609 applies the pressure only on the upper side of the finger.
  • the PPG sensors 611 are built into fixed contact points 612 on the underside of the finger that do not move. All other elements (stator 302, rotor 303, spring 304, transmission element 305, gear element 306, piston 307, cylinder 308, pressure sensor 310) are identical to the embodiment variant that was shown in FIG.
  • the application of pressure by the actuators described here produces oscillometric signals of sufficiently high quality. This was determined in comparison measurements with commercially available sensors for stationary measuring systems (CNAP, CNSystems Graz, Austria), which work with air pressure and therefore with pumps, valves and hoses.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Power Engineering (AREA)
  • Mechanical Engineering (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)

Abstract

L'invention concerne un dispositif portable pour générer une pression variable à une extrémité contenant une artère, le dispositif comprenant un boîtier (300, 600) ou une pièce de boîtier qui peut être fixée à l'extrémité et qui est appropriée pour entourer au moins partiellement l'extrémité, et comprenant une bulle souple (309, 609) qui est supportée sur le boîtier (300, 600), agit sur l'extrémité et est remplie d'un fluide. Selon l'invention, la bulle souple (309, 609) est remplie d'un fluide incompressible, par exemple un liquide ou un gel, et un actionneur qui est en contact avec le fluide incompressible ou la bulle souple (309, 609) et est approprié pour faire varier la pression du fluide incompressible est placé dans ou sur le boîtier (300, 600).
PCT/AT2021/060420 2020-11-12 2021-11-09 Dispositif portable pour générer une pression variable à une extrémité WO2022099337A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ATA50983/2020 2020-11-12
ATA50983/2020A AT524038B1 (de) 2020-11-12 2020-11-12 Tragbare vorrichtung zur erzeugung eines variablen drucks an einer extremität

Publications (1)

Publication Number Publication Date
WO2022099337A1 true WO2022099337A1 (fr) 2022-05-19

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WO (1) WO2022099337A1 (fr)

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1179991B1 (fr) 1999-03-30 2006-05-10 CNSystems Medizintechnik GmbH Tensiometre non invasif a mesure continue
US20120245471A1 (en) * 2009-10-15 2012-09-27 Finapres Medical Systems B.V. Device for controlling the pressure in an inflatable pressure pad
EP2854626A1 (fr) 2012-05-31 2015-04-08 Cnsystems Medizintechnik Gmbh Procédé et dispositif pour déterminer la pression artérielle de façon continue et non invasive
WO2016110781A1 (fr) 2015-01-08 2016-07-14 Cnsystems Medizintechnik Ag Capteur hémodynamique portable
US20180206789A1 (en) * 2017-01-24 2018-07-26 Edwards Lifesciences Corporation Extremity cuff such as a finger cuff, a method and a computer program product
US20180289271A1 (en) * 2017-04-11 2018-10-11 Edwards Lifesciences Corporation Blood pressure measurement device wearable by a patient
EP3419515B1 (fr) 2016-02-22 2020-07-22 CNSystems Medizintechnik AG Procédé et système de mesure pour la détermination continue de la pression sanguine intra-artérielle
WO2020176214A1 (fr) 2019-02-26 2020-09-03 Edwards Lifesciences Corporation Dispositif de brassard digital avec pince de non-volume, procédé de mesure de pression de non-pléthysmographie pour une mesure de pression artérielle non invasive continue

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5640964A (en) * 1995-02-16 1997-06-24 Medwave, Inc. Wrist mounted blood pressure sensor
US20070287923A1 (en) * 2006-05-15 2007-12-13 Charles Adkins Wrist plethysmograph
CN104757956A (zh) * 2015-03-26 2015-07-08 京东方科技集团股份有限公司 智能穿戴设备和测量体征的方法
US20180338694A1 (en) * 2017-05-23 2018-11-29 Edwards Lifesciences Corporation Method for correcting cuff pressure in a non-invasive blood pressure measurement

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1179991B1 (fr) 1999-03-30 2006-05-10 CNSystems Medizintechnik GmbH Tensiometre non invasif a mesure continue
US20120245471A1 (en) * 2009-10-15 2012-09-27 Finapres Medical Systems B.V. Device for controlling the pressure in an inflatable pressure pad
EP2854626A1 (fr) 2012-05-31 2015-04-08 Cnsystems Medizintechnik Gmbh Procédé et dispositif pour déterminer la pression artérielle de façon continue et non invasive
EP2854626B1 (fr) 2012-05-31 2020-06-03 CNSystems Medizintechnik AG Procédé et dispositif pour déterminer la pression artérielle de façon continue et non invasive
WO2016110781A1 (fr) 2015-01-08 2016-07-14 Cnsystems Medizintechnik Ag Capteur hémodynamique portable
US20160198955A1 (en) * 2015-01-08 2016-07-14 Cnsystems Medizintechnik Ag Wearable hemodynamic sensor
EP3242591A1 (fr) 2015-01-08 2017-11-15 CNSystems Medizintechnik AG Capteur hémodynamique portable
EP3419515B1 (fr) 2016-02-22 2020-07-22 CNSystems Medizintechnik AG Procédé et système de mesure pour la détermination continue de la pression sanguine intra-artérielle
US20180206789A1 (en) * 2017-01-24 2018-07-26 Edwards Lifesciences Corporation Extremity cuff such as a finger cuff, a method and a computer program product
US20180289271A1 (en) * 2017-04-11 2018-10-11 Edwards Lifesciences Corporation Blood pressure measurement device wearable by a patient
WO2020176214A1 (fr) 2019-02-26 2020-09-03 Edwards Lifesciences Corporation Dispositif de brassard digital avec pince de non-volume, procédé de mesure de pression de non-pléthysmographie pour une mesure de pression artérielle non invasive continue

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Publication number Publication date
AT524038B1 (de) 2022-02-15
AT524038A4 (de) 2022-02-15

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