WO2022097783A1 - Photothermal therapeutic catheter for endoscope, catheter system using same, and control method therefor - Google Patents

Photothermal therapeutic catheter for endoscope, catheter system using same, and control method therefor Download PDF

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Publication number
WO2022097783A1
WO2022097783A1 PCT/KR2020/015465 KR2020015465W WO2022097783A1 WO 2022097783 A1 WO2022097783 A1 WO 2022097783A1 KR 2020015465 W KR2020015465 W KR 2020015465W WO 2022097783 A1 WO2022097783 A1 WO 2022097783A1
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catheter
laser
fiber
thermal
thermal imaging
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PCT/KR2020/015465
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French (fr)
Korean (ko)
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안재성
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한국광기술원
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B18/22—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
    • A61B18/24—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor with a catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/005—Flexible endoscopes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • A61B1/05—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances characterised by the image sensor, e.g. camera, being in the distal end portion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/07—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements using light-conductive means, e.g. optical fibres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B18/22—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B18/22—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
    • A61B18/28—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor for heating a thermal probe or absorber
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636—Sensing and controlling the application of energy
    • A61B2018/00773—Sensed parameters
    • A61B2018/00791—Temperature
    • A61B2018/00809—Temperature measured thermochromatically
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00982—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body combined with or comprising means for visual or photographic inspections inside the body, e.g. endoscopes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B18/22—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
    • A61B2018/2205—Characteristics of fibres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B18/22—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
    • A61B2018/225—Features of hand-pieces
    • A61B2018/2253—Features of hand-pieces characterised by additional functions, e.g. surface cooling or detecting pathological tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B18/22—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
    • A61B2018/2255—Optical elements at the distal end of probe tips
    • A61B2018/2266—Optical elements at the distal end of probe tips with a lens, e.g. ball tipped

Definitions

  • the present invention relates to an endoscopic photothermal therapy catheter, a catheter system and method using the same, and more particularly, a laser fiber configured in the center to irradiate a therapeutic laser to tissue, and a lens around the laser fiber
  • An endoscopic photothermal therapy catheter for acquiring a plurality of partial thermal images and then synthesizing them to obtain a synthetic thermal image for the entire tissue through a catheter including a plurality of fibers for thermal imaging provided with a thermal image, this It relates to a catheter system and method used.
  • a catheter is inserted into an organ inside the body, such as a body cavity, stomach, intestine, bladder, etc., and is used to diagnose the condition of the organ tissue or to treat the tissue.
  • Such a catheter includes an image acquisition means for photographing and displaying an image of an internal organ tissue so that the state of the internal organ tissue can be checked, and a treatment means for treating the internal organ tissue.
  • the treatment means may be a drug, a laser, or the like, and the image obtained through the image acquisition means may be a thermal image or the like.
  • the catheter includes one or two image acquisition means and one treatment means is configured.
  • the therapist should determine the state of the tissue after acquiring an image by adjusting the direction of the tip of the catheter inserted into the tissue several times to examine the state of the entire tissue to be observed after the catheter is inserted.
  • the therapist has to adjust the shooting direction of the distal end of the catheter, so the operation is difficult.
  • the therapist must recognize which part of the tissue the location is by looking at the image acquired through the conventional catheter, but there is a problem that it may be difficult to determine which part of the tissue is the corresponding part depending on the skill of the therapist. there was.
  • an object of the present invention to include a laser fiber for irradiating a therapeutic laser to tissue and a plurality of thermal imaging fibers provided with a lens around the laser fiber to obtain a thermal image
  • An object of the present invention is to provide an endoscopic photothermal therapy catheter for acquiring a plurality of partial thermal images through a catheter and then synthesizing them to obtain a synthetic thermal image for the entire tissue, and a catheter system and method using the same.
  • the catheter for an endoscope according to the present invention for achieving the above object includes: an external protective cable; a laser fiber configured in the center of the external protection cable to transmit the laser supplied to one end and irradiate the laser to the other end; and a plurality of thermal imaging fibers configured inside the external protection cable, configured along an outer circumferential surface of the laser fiber, and configured with a thermal image acquisition lens at an end thereof.
  • the laser fiber is a TECS MM (Technology Enhanced Clad Silica Multimode) fiber
  • the thermal imaging fiber is a hollow core fiber.
  • the thermal imaging fiber has an outer diameter of 665 um and an internal diameter of 300 um, and the number of the thermal imaging fibers is 6 but is circularly disposed along the outer circumferential surface of the laser fiber.
  • a catheter system using an endoscopic catheter according to the present invention for achieving the above object is: an external protection cable, a laser configured in the center of the external protection cable to transmit the laser supplied to one end and irradiate the laser to the other end a catheter comprising a fiber for thermal imaging and a plurality of internal protective cables, configured along an outer circumferential surface of the laser fiber, and including a thermal imaging fiber having a thermal image acquisition lens at an end thereof; and a catheter control module for acquiring a thermal image through the plurality of thermal imaging fibers, synthesizing the plurality of acquired thermal images to generate a composite thermal image, and displaying the synthesized thermal image on a display means.
  • the catheter control module may include: a laser generating unit for injecting a laser into the laser fiber; a plurality of thermal image acquisition units connected to each of the thermal imaging fibers having a unique sequential identification number and outputting thermal images and identification information for images formed on lenses of the thermal imaging fibers; and a thermal image matching unit generating the synthesized thermal image by synthesizing the thermal images input from the thermal image acquisition units based on the identification information and the arrangement of the plurality of thermal imaging fibers.
  • the catheter system control method using an endoscopic catheter according to the present invention for achieving the above object is:
  • the catheter control module generates a laser and irradiates the tissue of internal organs through the laser fiber configured in the center of the catheter.
  • laser irradiation process a thermal image acquisition process of acquiring thermal images formed on each lens of the end of a plurality of thermal imaging fibers formed in a circular shape along the outer circumferential surface of the laser fiber of the catheter for tissue generating heat induced by the laser irradiation; and a synthetic thermal image acquisition process of synthesizing the plurality of thermal images based on a circular shape of the thermal imaging fiber and sequential identification information to obtain a synthesized thermal image.
  • the catheter system Since the present invention is composed of a laser fiber capable of irradiating a laser in one catheter and a thermal imaging fiber capable of acquiring a thermal image around the laser fiber, the catheter system has the effect of taking a wide picture of the tissue to be treated. there is.
  • the catheter of the present invention allows the tissue to be photographed widely by a plurality of thermal imaging fibers, and the catheter system of the present invention allows the therapist to obtain a thermal image of the entire tissue by minimizing the movement of the catheter tip.
  • the present invention has the effect of making it easy for the therapist to operate the catheter and minimizing the therapist's diagnosis time.
  • the catheter of the present invention is configured in the form of a circular cable, and a circular laser irradiation fiber configured in the central part and a plurality of thermal imaging fibers are configured along the outer circumferential surface of the laser irradiation fiber to obtain a plurality of thermal images.
  • FIG. 1 is a view showing the configuration of an endoscopic photothermal therapy catheter according to the present invention.
  • Figure 2 is a view showing a cross-sectional view A-A' of the photothermal therapy catheter for endoscopic of Figure 1 according to the present invention.
  • FIG. 3 is a view showing the configuration of a catheter system using the photothermal catheter for endoscopic treatment according to the present invention.
  • FIG. 4 is a view for explaining a method of obtaining and synthesizing a thermal image of a catheter system using an endoscopic catheter according to the present invention.
  • FIG. 1 is a view showing the configuration of an endoscopic photothermal therapy catheter according to the present invention
  • Figure 2 is a view showing a cross-sectional view A-A' of the endoscopic photothermal therapy catheter of FIG. 1 according to the present invention
  • Reference numeral 100 in the drawings denotes a photothermal therapy catheter for endoscopic use. Hereinafter, it will be described with reference to FIGS. 1 and 2 .
  • the photothermal therapy catheter 100 for endoscopy includes an external protection cable 110 , a laser fiber 120 , and a plurality of thermal imaging fibers 130 .
  • the external protection cable 110 is also referred to as a shaft, is made of a flexible material, is configured in a cylindrical shape, has a hollow inside, and preferably has an outer diameter of less than 2.7 mm.
  • the hollow portion may be configured to correspond to the circular arrangement shape of the laser fiber 120 and the plurality of thermal imaging fibers 130 according to the present invention, or a number corresponding to the number of the laser optical fiber and the plurality of thermal imaging fibers. There will be.
  • the laser fiber 120 is configured along the central or central hollow portion of the hollow portion (when each hollow portion corresponding to the laser fiber 120 and the plurality of thermal imaging fibers 130 is provided), one side It is configured so that the laser is incident and delivered to the other side, so that the laser is emitted from the other side.
  • a technology-reinforced clad silica multimode fiber composed of a silica core, a cladding part (Fluorine-Doped Silica Cladding), a coating part (TECS Hard Polymer Coating), and a buffer part (Tefzel Buffer). It would be desirable to apply (Technology Enhanced Clad Silica Multimode: TECS MM Fiber).
  • the diameter of the silica core is 550w19um
  • the diameter of the cladding part is 600m10um
  • the diameter of the coating part is 630m10um
  • the diameter of the buffer part is 1040m30um.
  • the thermal imaging fiber 130 may be formed in a circular shape at regular intervals along the outer circumferential surface of the laser fiber 120 as shown in FIG. 1 .
  • the thermal imaging fiber 130 has an outer diameter of 665um and an inner diameter of 300um, an optical fiber is routed inside, and a silicon lens (Si Lens) 131 is formed at the end of the fiber 130 in the direction of being inserted into the internal organs of the body.
  • Si Lens silicon lens
  • a hollow core fiber may be applied as the thermal imaging fiber 130 .
  • the thermal imaging fiber 130 may be composed of a plurality of fibers, preferably six.
  • FIG. 3 is a view showing the configuration of a catheter system using the catheter for endoscopic photothermal therapy according to the present invention
  • FIG. 4 is a view for explaining a method for obtaining and synthesizing a thermal image of the catheter system using the endoscopic catheter according to the present invention. .
  • FIGS. 3 and 4 it will be described with reference to FIGS. 3 and 4 .
  • the catheter system includes an endoscopic photothermal therapy catheter 100 and a catheter control module 200 .
  • the catheter control module 200 includes a thermal image acquisition unit 210, a thermal image matching unit 220 and a laser generating unit 230 corresponding to the number of thermal imaging fibers 130 of the endoscopic photothermal therapy catheter 100.
  • the laser generating unit 230 generates a laser such as 808 nm and makes it incident on the laser fiber 120 of the photothermal therapy catheter 100 for the endoscope.
  • the laser will be transmitted through the laser fiber 120 and emitted from the output terminal to the tissue inside the body organs. The tissue exposed to the laser will be heated by the laser.
  • the thermal image acquisition unit 210 converts the thermal image 132 obtained by photographing the tissue generating heat by the laser at the corresponding location through the connected thermal imaging fiber 130 to the thermal image matching unit 220 . ) is output.
  • the thermal image matching unit 220 defines and has sequential unique identification information for the thermal image acquisition unit 210 , that is, the thermal imaging fiber 130 , and has a plurality of After arranging the thermal images 132-1, 132-2, ..., 132-6 in the form of the thermal image fiber 130 (circular form in FIG. 4) with defined identification information, a general image synthesis technique is applied. to generate the synthesized thermal image 133 and output it through an output means (not shown).
  • the output means may be a display means such as a liquid crystal display (LCD).
  • thermal image acquisition unit 220 thermal image matching unit

Abstract

The present invention relates to a photothermal therapeutic catheter for an endoscope, a catheter system using same, and a method, and, more specifically, to a photothermal therapeutic catheter for an endoscope and a catheter system using same, and a method, the catheter comprising: a laser fiber formed at a central part to emit a therapeutic laser beam at tissue; and a plurality of thermal imaging fibers having lenses provided around the laser fiber so as to be capable of acquiring a thermal image, and thus the present invention acquires a plurality of partial thermal images through a catheter, and then synthesizes the acquired plurality of partial thermal images to acquire a synthesized thermal image of all the tissue.

Description

내시경용 광열치료 카테터, 이를 이용한 카테터 시스템 및 그 제어 방법Endoscopic photothermal catheter, catheter system using same, and method for controlling the same
본 발명은 내시경용 광열치료 카테터, 이를 이용한 카테터 시스템 및 방법에 관한 것으로, 더욱 상세하게는 중심부에 구성되어 조직(Tissue)에 치료용 레이저를 조사하는 레이저용 파이버 및 상기 레이저용 파이버 주변으로 렌즈가 구비되어 열화상을 획득할 수 있도록 하는 다수의 열화상용 파이버를 포함하는 카테터를 통해 다수개의 부분 열화상을 획득한 후 합성하여 상기 조직 전체에 대한 합성 열화상을 획득하는 내시경용 광열치료 카테터, 이를 이용한 카테터 시스템 및 방법에 관한 것이다.The present invention relates to an endoscopic photothermal therapy catheter, a catheter system and method using the same, and more particularly, a laser fiber configured in the center to irradiate a therapeutic laser to tissue, and a lens around the laser fiber An endoscopic photothermal therapy catheter for acquiring a plurality of partial thermal images and then synthesizing them to obtain a synthetic thermal image for the entire tissue through a catheter including a plurality of fibers for thermal imaging provided with a thermal image, this It relates to a catheter system and method used.
카테터는 체강, 위, 창자, 방광 등의 신체 내부의 장기 속에 넣어 해당 장기 조직의 상태를 진단하거나 조직을 치료하는 데 사용된다.A catheter is inserted into an organ inside the body, such as a body cavity, stomach, intestine, bladder, etc., and is used to diagnose the condition of the organ tissue or to treat the tissue.
이러한 카테터는 내부 장기의 조직의 상태를 확인할 수 있도록 내부 장기 조직을 촬영하여 영상으로 표시하는 영상 획득 수단 및 내부 장기 조직을 치료할 수 있는 치료 수단을 포함한다.Such a catheter includes an image acquisition means for photographing and displaying an image of an internal organ tissue so that the state of the internal organ tissue can be checked, and a treatment means for treating the internal organ tissue.
치료 수단은 약물, 레이저 등이 될 수 있고, 영상 획득 수단을 통해 획득되는 영상은 열화상 등이 될 수 있을 것이다.The treatment means may be a drug, a laser, or the like, and the image obtained through the image acquisition means may be a thermal image or the like.
통상 카테터는 하나 또는 두 개의 영상 획득 수단을 포함하고 하나의 치료 수단이 구성된다.Typically, the catheter includes one or two image acquisition means and one treatment means is configured.
따라서 치료자는 카테터의 삽입 후 관찰하고자 하는 조직 전체의 상태를 검사하기 위해 조직 내부로 투입된 카테터의 끝단부의 방향을 여러 번 조정하여 영상을 획득한 후 조직의 상태를 판단하여야 한다.Therefore, the therapist should determine the state of the tissue after acquiring an image by adjusting the direction of the tip of the catheter inserted into the tissue several times to examine the state of the entire tissue to be observed after the catheter is inserted.
상술한 바와 같이 치료자는 카테터의 끝단부의 촬영 방향을 조절하여야 하므로 그 조작이 어려운 문제점이 있었다.As described above, the therapist has to adjust the shooting direction of the distal end of the catheter, so the operation is difficult.
또한, 치료자는 종래 카테터를 통해 획득되는 영상을 보고 그 위치가 조직의 어는 부분인지를 인지하여야 하나, 치료자의 능숙도에 따라 해당 부분이 조직의 어떤 부분인지를 파악하는 데 어려움을 겪을 수 있는 문제점이 있었다.In addition, the therapist must recognize which part of the tissue the location is by looking at the image acquired through the conventional catheter, but there is a problem that it may be difficult to determine which part of the tissue is the corresponding part depending on the skill of the therapist. there was.
따라서 본 발명의 목적은 중심부에 구성되어 조직(Tissue)에 치료용 레이저를 조사하는 레이저용 파이버 및 상기 레이저용 파이버 주변으로 렌즈가 구비되어 열화상을 획득할 수 있도록 하는 다수의 열화상용 파이버를 포함하는 카테터를 통해 다수개의 부분 열화상을 획득한 후 합성하여 상기 조직 전체에 대한 합성 열화상을 획득하는 내시경용 광열치료 카테터, 이를 이용한 카테터 시스템 및 방법을 제공함에 있다.Accordingly, it is an object of the present invention to include a laser fiber for irradiating a therapeutic laser to tissue and a plurality of thermal imaging fibers provided with a lens around the laser fiber to obtain a thermal image An object of the present invention is to provide an endoscopic photothermal therapy catheter for acquiring a plurality of partial thermal images through a catheter and then synthesizing them to obtain a synthetic thermal image for the entire tissue, and a catheter system and method using the same.
상기와 같은 목적을 달성하기 위한 본 발명에 따른 내시경용 카테터는: 외부 보호 케이블; 상기 외부 보호 케이블의 중심부에 구성되어 일단으로 공급되는 레이저를 전달하여 타단으로 상기 레이저를 조사하는 레이저용 파이버; 및 상기 외부 보호 케이블 내측에 다수 개가 구성되되, 상기 레이저용 파이버의 외주면을 따라 구성되고 끝단에 열화상 획득용 렌즈가 구성되는 열화상용 파이버를 포함하는 것을 특징으로 한다.The catheter for an endoscope according to the present invention for achieving the above object includes: an external protective cable; a laser fiber configured in the center of the external protection cable to transmit the laser supplied to one end and irradiate the laser to the other end; and a plurality of thermal imaging fibers configured inside the external protection cable, configured along an outer circumferential surface of the laser fiber, and configured with a thermal image acquisition lens at an end thereof.
상기 레이저용 파이버는 TECS MM(Technology Enhanced Clad Silica Multimode) 파이버이고, 상기 열화상용 파이버는 할로우 코어 파이버(Hollow Core Fiber)인 것을 특징으로 한다.The laser fiber is a TECS MM (Technology Enhanced Clad Silica Multimode) fiber, and the thermal imaging fiber is a hollow core fiber.
상기 열화상용 파이버는, 외경이 665um이고 내경이 300um이며, 상기 열화상용 파이버의 개수는 6개이되 레이저용 파이버의 외주면을 따라 원형으로 배치되는 것을 특징으로 한다.The thermal imaging fiber has an outer diameter of 665 um and an internal diameter of 300 um, and the number of the thermal imaging fibers is 6 but is circularly disposed along the outer circumferential surface of the laser fiber.
상기와 같은 목적을 달성하기 위한 본 발명에 따른 내시경용 카테터를 이용한 카테터 시스템은: 외부 보호 케이블, 상기 외부 보호 케이블의 중심부에 구성되어 일단으로 공급되는 레이저를 전달하여 타단으로 상기 레이저를 조사하는 레이저용 파이버 및 상기 외부 보호 케이블 내측에 다수 개가 구성되되, 상기 레이저용 파이버의 외주면을 따라 구성되고 끝단에 열화상 획득용 렌즈가 구성되는 열화상용 파이버를 포함하는 카테터; 및 상기 다수의 열화상용 파이버를 통해 열화상을 획득하고, 획득된 다수의 열화상을 합성하여 합성 열화상을 생성하여 표시수단에 표시하는 카테터 제어모듈을 포함하는 것을 특징으로 한다.A catheter system using an endoscopic catheter according to the present invention for achieving the above object is: an external protection cable, a laser configured in the center of the external protection cable to transmit the laser supplied to one end and irradiate the laser to the other end a catheter comprising a fiber for thermal imaging and a plurality of internal protective cables, configured along an outer circumferential surface of the laser fiber, and including a thermal imaging fiber having a thermal image acquisition lens at an end thereof; and a catheter control module for acquiring a thermal image through the plurality of thermal imaging fibers, synthesizing the plurality of acquired thermal images to generate a composite thermal image, and displaying the synthesized thermal image on a display means.
상기 카테터 제어모듈은, 상기 레이저용 파이버로 레이저를 입사시키는 레이저 생성부; 고유의 순차적인 식별번호를 가지고 상기 열화상용 파이버 각각에 연결되어 연결된 열화상용 파이버의 렌즈에 맺힌 상에 대한 열화상 및 식별정보를 출력하는 다수의 열화상 획득부; 및 상기 열화상 획득부들로부터 입력되는 열화상을 상기 식별정보 및 상기 다수의 열화상용 파이버의 배열 형태에 근거하여 합성하여 상기 합성 열화상을 생성하는 열화상 정합부를 포함하는 것을 특징으로 한다.The catheter control module may include: a laser generating unit for injecting a laser into the laser fiber; a plurality of thermal image acquisition units connected to each of the thermal imaging fibers having a unique sequential identification number and outputting thermal images and identification information for images formed on lenses of the thermal imaging fibers; and a thermal image matching unit generating the synthesized thermal image by synthesizing the thermal images input from the thermal image acquisition units based on the identification information and the arrangement of the plurality of thermal imaging fibers.
상기와 같은 목적을 달성하기 위한 본 발명에 따른 내시경용 카테터를 이용한 카테터 시스템 제어 방법은: 카테터 제어모듈이 레이저를 생성하여 카테터의 중심부에 구성되는 레이저용 파이버를 통해 신체 내부 장기의 조직에 조사하는 레이저 조사 과정; 상기 레이저의 조사에 의해 유도된 열을 발생하는 조직을 상기 카테터의 레이저용 파이버의 외주면을 따라 원형으로 형성되는 다수의 열화상용 파이버 끝단의 각 렌즈에 맺힌 열화상들을 획득하는 열화상 획득 과정; 및 상기 다수의 열화상을 상기 열화상용 파이버의 원형 형태 및 순차적인 식별정보에 근거하여 합성하여 합성 열화상을 획득하는 합성 열화상 획득 과정을 포함하는 것을 특징으로 한다.The catheter system control method using an endoscopic catheter according to the present invention for achieving the above object is: The catheter control module generates a laser and irradiates the tissue of internal organs through the laser fiber configured in the center of the catheter. laser irradiation process; a thermal image acquisition process of acquiring thermal images formed on each lens of the end of a plurality of thermal imaging fibers formed in a circular shape along the outer circumferential surface of the laser fiber of the catheter for tissue generating heat induced by the laser irradiation; and a synthetic thermal image acquisition process of synthesizing the plurality of thermal images based on a circular shape of the thermal imaging fiber and sequential identification information to obtain a synthesized thermal image.
본 발명은 하나의 카테터 내에 레이저를 조사할 수 있는 레이저용 파이버와 상기 레이저용 파이버 주변으로 열화상을 획득할 수 있는 열화상용 파이버가 구성되므로, 카테터 시스템은 치료 대상 조직을 넓게 촬영할 수 있는 효과가 있다.Since the present invention is composed of a laser fiber capable of irradiating a laser in one catheter and a thermal imaging fiber capable of acquiring a thermal image around the laser fiber, the catheter system has the effect of taking a wide picture of the tissue to be treated. there is.
또한, 본 발명의 카테터는 다수의 열화상용 파이버에 의해 조직을 넓게 촬영할 수 있도록 하고, 본 발명의 카테터 시스템은 치료자가 카테터 끝단부의 움직임을 최소로 조작하여 전체 조직에 대한 열화상을 획득할 수 있도록 함으로써 본 발명은 치료자의 카테터 조작을 쉽게 하게 하고, 치료자의 진단 시간을 최소화할 수 있는 효과가 있다.In addition, the catheter of the present invention allows the tissue to be photographed widely by a plurality of thermal imaging fibers, and the catheter system of the present invention allows the therapist to obtain a thermal image of the entire tissue by minimizing the movement of the catheter tip. By doing so, the present invention has the effect of making it easy for the therapist to operate the catheter and minimizing the therapist's diagnosis time.
또한, 본 발명의 카테터는 원형의 케이블 형태로 구성되고, 중앙부에 구성되는 원형의 레이저 조사용 파이버와 상기 레이저 조사용 파이버의 외주면을 따라 다수의 열화상용 파이버들이 구성되어 다수의 열화상을 획득하므로 다수의 열화상 합성이 용이한 효과가 있다.In addition, the catheter of the present invention is configured in the form of a circular cable, and a circular laser irradiation fiber configured in the central part and a plurality of thermal imaging fibers are configured along the outer circumferential surface of the laser irradiation fiber to obtain a plurality of thermal images. There is an effect that it is easy to synthesize a number of thermal images.
도 1은 본 발명에 따른 내시경용 광열치료 카테터의 구성을 나타낸 도면이다.1 is a view showing the configuration of an endoscopic photothermal therapy catheter according to the present invention.
도 2는 본 발명에 따른 도 1의 내시경용 광열치료 카테터의 A-A'단면도를 나타낸 도면이다.Figure 2 is a view showing a cross-sectional view A-A' of the photothermal therapy catheter for endoscopic of Figure 1 according to the present invention.
도 3은 본 발명에 따른 내시경용 광열치료 카테터를 이용한 카테터 시스템의 구성을 나타낸 도면이다.3 is a view showing the configuration of a catheter system using the photothermal catheter for endoscopic treatment according to the present invention.
도 4는 본 발명에 따른 내시용 카테터를 이용한 카테터 시스템의 열화상 획득 및 합성 방법을 설명하기 위한 도면이다.4 is a view for explaining a method of obtaining and synthesizing a thermal image of a catheter system using an endoscopic catheter according to the present invention.
이하 첨부된 도면을 참조하여 본 발명에 따른 내시경용 광열치료 카테터, 내시경용 광열치료 카테터를 이용한 카테터 시스템의 구성 및 동작을 설명하고, 상기 시스템의 제어 방법을 설명한다.Hereinafter, with reference to the accompanying drawings, the configuration and operation of the catheter system using the photothermal therapy catheter for endoscopic endoscopy and the photothermal therapy catheter for the endoscope according to the present invention will be described, and a control method of the system will be described.
도 1은 본 발명에 따른 내시경용 광열치료 카테터의 구성을 나타낸 도면이고, 도 2는 본 발명에 따른 도 1의 내시경용 광열치료 카테터의 A-A'단면도를 나타낸 도면이다. 도면에 참조된 부호 100은 내시경용 광열치료 카테터이다. 이하 도 1 및 도 2를 참조하여 설명한다.1 is a view showing the configuration of an endoscopic photothermal therapy catheter according to the present invention, Figure 2 is a view showing a cross-sectional view A-A' of the endoscopic photothermal therapy catheter of FIG. 1 according to the present invention. Reference numeral 100 in the drawings denotes a photothermal therapy catheter for endoscopic use. Hereinafter, it will be described with reference to FIGS. 1 and 2 .
본 발명에 따른 내시경용 광열치료 카테터(100)는 외부 보호 케이블(110), 레이저용 파이버(120) 및 다수의 열화상용 파이버(130)를 포함한다.The photothermal therapy catheter 100 for endoscopy according to the present invention includes an external protection cable 110 , a laser fiber 120 , and a plurality of thermal imaging fibers 130 .
상기 외부 보호 케이블(110)은 샤프트라고도 하며, 플렉시블한 재질로 원통 형상으로 구성되고 내측으로 중공부가 형성되며, 외경이 2.7mm 미만인 것이 바람직할 것이다. 상기 중공부는 본 발명에 따른 레이저용 파이버(120) 및 다수의 열화상용 파이버(130)의 원형 배치 형태에 대응하도록 하나, 또는 레이저용 파이버 및 다수의 열화상용 파이버의 개수에 대응하는 수로 구성될 수도 있을 것이다.The external protection cable 110 is also referred to as a shaft, is made of a flexible material, is configured in a cylindrical shape, has a hollow inside, and preferably has an outer diameter of less than 2.7 mm. The hollow portion may be configured to correspond to the circular arrangement shape of the laser fiber 120 and the plurality of thermal imaging fibers 130 according to the present invention, or a number corresponding to the number of the laser optical fiber and the plurality of thermal imaging fibers. There will be.
상기 레이저용 파이버(120)는 상기 중공부의 중심부 또는 중심의 중공부(레이저용 파이버(120) 및 다수의 열화상 파이버(130)에 대응하는 각각의 중공부를 구비하는 경우)를 따라 구성되어, 일측으로 레이저를 입사받아 타측으로 전달하여 타측에서 레이저가 출사되도록 구성된다.The laser fiber 120 is configured along the central or central hollow portion of the hollow portion (when each hollow portion corresponding to the laser fiber 120 and the plurality of thermal imaging fibers 130 is provided), one side It is configured so that the laser is incident and delivered to the other side, so that the laser is emitted from the other side.
레이저용 파이버(120)로는 실리카 코어(Silica Core), 클래딩부(Fluorine-Doped Silica Cladding), 코팅부(TECS Hard Polymer Coating), 및 버퍼부(Tefzel Buffer)로 구성되는 기술강화 클리드 실리카 다중모드 파이버(Technology Enhanced Clad Silica Multimode: TECS MM Fiber)를 적용하는 것이 바람직할 것이다. 상기 실리카 코어의 지름은 550ㅁ19um, 클래딩부의 지름은 600ㅁ10um, 코팅부의 지름은 630ㅁ10um이며, 버퍼부의 지름은 1040ㅁ30um이다.As the laser fiber 120, a technology-reinforced clad silica multimode fiber composed of a silica core, a cladding part (Fluorine-Doped Silica Cladding), a coating part (TECS Hard Polymer Coating), and a buffer part (Tefzel Buffer). It would be desirable to apply (Technology Enhanced Clad Silica Multimode: TECS MM Fiber). The diameter of the silica core is 550w19um, the diameter of the cladding part is 600m10um, the diameter of the coating part is 630m10um, and the diameter of the buffer part is 1040m30um.
열화상용 파이버(130)는 도 1에서 보이는 바와 같이 상기 레이저용 파이버(120)의 외주면을 따라 일정 간격으로 원형으로 구성될 수 있을 것이다.The thermal imaging fiber 130 may be formed in a circular shape at regular intervals along the outer circumferential surface of the laser fiber 120 as shown in FIG. 1 .
상기 열화상용 파이버(130)는 외경이 665um이고 내경이 300um이며, 내측으로 광섬유가 배선되며 신체 내부 장기에 삽입되는 방향의 끝단에는 실리콘 렌즈(Si Lens)(131)가 구성된다.The thermal imaging fiber 130 has an outer diameter of 665um and an inner diameter of 300um, an optical fiber is routed inside, and a silicon lens (Si Lens) 131 is formed at the end of the fiber 130 in the direction of being inserted into the internal organs of the body.
상기 열화상용 파이버(130)로는 할로우 코어 파이버(Hollow Core Fiber)가 적용될 수 있을 것이다.A hollow core fiber may be applied as the thermal imaging fiber 130 .
상기 열화상용 파이버(130)는 다수 개로 구성될 수 있으며, 6개인 것이 바람직할 것이다.The thermal imaging fiber 130 may be composed of a plurality of fibers, preferably six.
도 3은 본 발명에 따른 내시경용 광열치료 카테터를 이용한 카테터 시스템의 구성을 나타낸 도면이고, 도 4는 본 발명에 따른 내시용 카테터를 이용한 카테터 시스템의 열화상 획득 및 합성 방법을 설명하기 위한 도면이다. 이하 도 3 및 도 4를 참조하여 설명한다.3 is a view showing the configuration of a catheter system using the catheter for endoscopic photothermal therapy according to the present invention, and FIG. 4 is a view for explaining a method for obtaining and synthesizing a thermal image of the catheter system using the endoscopic catheter according to the present invention. . Hereinafter, it will be described with reference to FIGS. 3 and 4 .
카테터 시스템은 내시경용 광열치료 카테터(100) 및 카테터 제어모듈(200)을 포함한다.The catheter system includes an endoscopic photothermal therapy catheter 100 and a catheter control module 200 .
내시경용 광열치료 카테터(100)는 상술한 도 1 및 도 2에서 설명하였으므로 그 설명을 생략한다.Since the photothermal therapy catheter 100 for an endoscope has been described with reference to FIGS. 1 and 2 above, a description thereof will be omitted.
카테터 제어모듈(200)은 내시경용 광열치료 카테터(100)의 열화상용 파이버(130)의 수에 대응하는 열화상 획득부(210), 열화상 정합부(220) 및 레이저 생성부(230)를 포함한다.The catheter control module 200 includes a thermal image acquisition unit 210, a thermal image matching unit 220 and a laser generating unit 230 corresponding to the number of thermal imaging fibers 130 of the endoscopic photothermal therapy catheter 100. include
레이저 생성부(230)는 808nm 등의 레이저를 생성하여 내시경용 광열치료 카테터(100)의 레이저용 파이버(120)로 입사시킨다. 레이저는 레이저용 파이버(120)를 통해 전송되어 출력단에서 신체 장기 내부의 조직으로 출사될 것이다. 상기 레이저에 노출된 조직은 레이저에 의해 열이 발생될 것이다.The laser generating unit 230 generates a laser such as 808 nm and makes it incident on the laser fiber 120 of the photothermal therapy catheter 100 for the endoscope. The laser will be transmitted through the laser fiber 120 and emitted from the output terminal to the tissue inside the body organs. The tissue exposed to the laser will be heated by the laser.
열화상 획득부(210)는 도 4에 나타낸 바와 같이 연결된 열화상용 파이버(130)를 통해 해당 위치에서 상기 레이저에 의해 열을 발생하는 조직을 촬영한 열화상(132)을 열화상 정합부(220)로 출력한다.As shown in FIG. 4 , the thermal image acquisition unit 210 converts the thermal image 132 obtained by photographing the tissue generating heat by the laser at the corresponding location through the connected thermal imaging fiber 130 to the thermal image matching unit 220 . ) is output.
열화상 정합부(220)는 열화상 획득부(210), 즉 열화상용 파이버(130)에 대한 순차적인 고유한 식별정보를 정의하여 가지고 있으며, 열화상 획득부(210)들로부터 입력되는 다수의 열화상(132-1, 132-2,...,132-6)을 정의된 식별정보와 열화상용 파이버(130)의 형태(도 4의 원형 형태)로 배열한 후 일반적인 이미지 합성 기술을 적용하여 합성 열화상(133)을 생성하여 출력수단(미도시)을 통해 출력한다. 상기 출력수단은 액정표시장치(Liquid Crystal Display: LCD) 등의 표시수단일 수 있을 것이다.The thermal image matching unit 220 defines and has sequential unique identification information for the thermal image acquisition unit 210 , that is, the thermal imaging fiber 130 , and has a plurality of After arranging the thermal images 132-1, 132-2, ..., 132-6 in the form of the thermal image fiber 130 (circular form in FIG. 4) with defined identification information, a general image synthesis technique is applied. to generate the synthesized thermal image 133 and output it through an output means (not shown). The output means may be a display means such as a liquid crystal display (LCD).
한편, 본 발명은 전술한 전형적인 바람직한 실시예에만 한정되는 것이 아니라 본 발명의 요지를 벗어나지 않는 범위 내에서 여러 가지로 개량, 변경, 대체 또는 부가하여 실시할 수 있는 것임은 당해 기술분야에서 통상의 지식을 가진 자라면 용이하게 이해할 수 있을 것이다. 이러한 개량, 변경, 대체 또는 부가에 의한 실시가 이하의 첨부된 특허청구범위의 범주에 속하는 것이라면 그 기술사상 역시 본 발명에 속하는 것으로 보아야 한다.On the other hand, it is common knowledge in the art that the present invention is not limited to the typical preferred embodiments described above, but can be improved, changed, replaced, or added in various ways without departing from the spirit of the present invention. Those who have will be able to understand it easily. If implementation by such improvement, change, substitution, or addition falls within the scope of the appended claims below, the technical idea should also be regarded as belonging to the present invention.
[부호의 설명][Explanation of code]
100: 내시경용 광열치료 카테터 110: 외부 보호 케이블100: photothermal therapy catheter for endoscopic 110: external protection cable
120: 레이저용 파이버 130: 열화상용 파이버120: fiber for laser 130: fiber for thermal imaging
131: (실리콘) 렌즈(Si Lens) 132: 열화상131: (silicon) lens (Si Lens) 132: thermal image
133: 합성 열화상 200: 카테터 제어모듈133: synthetic thermal image 200: catheter control module
210: 열화상 획득부 220: 열화상 정합부210: thermal image acquisition unit 220: thermal image matching unit
230: 레이저 생성부230: laser generator

Claims (6)

  1. 외부 보호 케이블;external protection cable;
    상기 외부 보호 케이블의 중심부에 구성되어 일단으로 공급되는 레이저를 전달하여 타단으로 상기 레이저를 조사하는 레이저용 파이버; 및a laser fiber configured in the center of the external protection cable to transmit the laser supplied to one end and irradiate the laser to the other end; and
    상기 외부 보호 케이블 내측에 다수 개가 구성되되, 상기 레이저용 파이버의 외주면을 따라 구성되고 끝단에 열화상 획득용 렌즈가 구성되는 열화상용 파이버를 포함하는 것을 특징으로 하는 내시경용 광열치료 카테터.Endoscopic photothermal therapy catheter, characterized in that it comprises a plurality of fibers inside the external protection cable, which are configured along the outer circumferential surface of the laser fiber and include a thermal imaging fiber having a thermal image acquisition lens at the end.
  2. 제1항에 있어서,According to claim 1,
    상기 레이저용 파이버는 TECS MM(Technology Enhanced Clad Silica Multimode) 파이버이고, 상기 열화상용 파이버는 할로우 코어 파이버(Hollow Core Fiber)인 것을 특징으로 하는 내시경용 광열치료 카테터.The laser fiber is a TECS MM (Technology Enhanced Clad Silica Multimode) fiber, and the thermal imaging fiber is a hollow core fiber (Hollow Core Fiber).
  3. 제1항에 있어서,According to claim 1,
    상기 열화상용 파이버는,The thermal imaging fiber,
    외경이 665um이고 내경이 300um이며, 상기 열화상용 파이버의 개수는 6개이되 레이저용 파이버의 외주면을 따라 원형으로 배치되는 것을 특징으로 하는 내시경용 광열 치료 카테터.The outer diameter is 665um and the inner diameter is 300um, and the number of fibers for thermal imaging is 6 but is arranged in a circular shape along the outer peripheral surface of the laser fiber for endoscopic photothermal therapy catheter.
  4. 외부 보호 케이블, 상기 외부 보호 케이블의 중심부에 구성되어 일단으로 공급되는 레이저를 전달하여 타단으로 상기 레이저를 조사하는 레이저용 파이버 및 상기 외부 보호 케이블 내측에 다수 개가 구성되되, 상기 레이저용 파이버의 외주면을 따라 구성되고 끝단에 열화상 획득용 렌즈가 구성되는 열화상용 파이버를 포함하는 카테터; 및An external protection cable, a laser fiber configured in the center of the external protection cable to transmit the laser supplied to one end to irradiate the laser to the other end, and a plurality of fibers configured inside the external protection cable, the outer circumferential surface of the laser fiber A catheter comprising a thermal imaging fiber configured according to the end of the thermal imaging lens is configured; and
    상기 다수의 열화상용 파이버를 통해 열화상을 획득하고, 획득된 다수의 열화상을 합성하여 합성 열화상을 생성하여 표시수단에 표시하는 카테터 제어모듈을 포함하는 것을 특징으로 하는 내시경용 광열치료 카테터를 이용한 카테터 시스템.An endoscopic photothermal therapy catheter, characterized in that it includes a catheter control module for acquiring a thermal image through the plurality of thermal imaging fibers, synthesizing the plurality of acquired thermal images to generate a synthetic thermal image, and displaying it on a display means catheter system used.
  5. 제4항에 있어서,5. The method of claim 4,
    상기 카테터 제어모듈은,The catheter control module,
    상기 레이저용 파이버로 레이저를 입사시키는 레이저 생성부;a laser generating unit for injecting a laser into the laser fiber;
    고유의 순차적인 식별번호를 가지고 상기 열화상용 파이버 각각에 연결되어 연결된 열화상용 파이버의 렌즈에 맺힌 상에 대한 열화상 및 식별정보를 출력하는 다수의 열화상 획득부; 및a plurality of thermal image acquisition units connected to each of the thermal imaging fibers having a unique sequential identification number and outputting thermal images and identification information for images formed on lenses of the thermal imaging fibers; and
    상기 열화상 획득부들로부터 입력되는 열화상을 상기 식별정보 및 상기 다수의 열화상용 파이버의 배열형태에 근거하여 합성하여 상기 합성 열화상을 생성하는 열화상 정합부를 포함하는 것을 특징으로 내시경용 광열치료 카테터를 이용한 카테터 시스템.Endoscopic photothermal therapy catheter, characterized in that it comprises a thermal image matching unit for generating the synthesized thermal image by synthesizing the thermal images input from the thermal image acquisition units based on the identification information and the arrangement of the plurality of thermal imaging fibers. catheter system using
  6. 카테터 제어모듈이 레이저를 생성하여 카테터의 중심부에 구성되는 레이저용 파이버를 통해 신체 내부 장기의 조직에 조사하는 레이저 조사 과정;A laser irradiation process in which the catheter control module generates a laser and irradiates the tissue of internal organs through a laser fiber configured in the center of the catheter;
    상기 레이저의 조사에 의해 유도된 열을 발생하는 조직을 상기 카테터의 레이저용 파이버의 외주면을 따라 원형으로 형성되는 다수의 열화상용 파이버 끝단의 각 렌즈에 맺힌 열화상들을 획득하는 열화상 획득 과정; 및a thermal image acquisition process of acquiring thermal images formed on each lens of the end of a plurality of thermal imaging fibers formed in a circular shape along the outer circumferential surface of the laser fiber of the catheter for tissue generating heat induced by the laser irradiation; and
    상기 다수의 열화상을 상기 열화상용 파이버의 원형 형태 및 순차적인 식별정보에 근거하여 합성하여 합성 열화상을 획득하는 합성 열화상 획득 과정을 포함하는 것을 특징으로 하는 내시경용 광열치료 카테터를 이용한 카테터 시스템 제어 방법.Catheter system using a photothermal therapy catheter for endoscopy, characterized in that it includes a synthetic thermal image acquisition process of acquiring a synthetic thermal image by synthesizing the plurality of thermal images based on the circular shape of the thermal imaging fiber and sequential identification information. control method.
PCT/KR2020/015465 2020-11-05 2020-11-06 Photothermal therapeutic catheter for endoscope, catheter system using same, and control method therefor WO2022097783A1 (en)

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