WO2022057016A1 - 用于病毒检测的车载抽拉检测实验室以及车辆 - Google Patents

用于病毒检测的车载抽拉检测实验室以及车辆 Download PDF

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Publication number
WO2022057016A1
WO2022057016A1 PCT/CN2020/124382 CN2020124382W WO2022057016A1 WO 2022057016 A1 WO2022057016 A1 WO 2022057016A1 CN 2020124382 W CN2020124382 W CN 2020124382W WO 2022057016 A1 WO2022057016 A1 WO 2022057016A1
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WO
WIPO (PCT)
Prior art keywords
vehicle
laboratory
support frame
experimental
pull
Prior art date
Application number
PCT/CN2020/124382
Other languages
English (en)
French (fr)
Inventor
尹烨
苏运升
陈戊荣
李雯琪
陈堃
邱梦实
黄冠霖
刘中民
王韬
刘�东
唐子奇
王知然
李若羽
曾昊
熊小华
Original Assignee
深圳华大基因股份有限公司
上海易托邦建筑科技有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 深圳华大基因股份有限公司, 上海易托邦建筑科技有限公司 filed Critical 深圳华大基因股份有限公司
Priority to JP2021600197U priority Critical patent/JP3243601U/ja
Priority to DE212020000672.5U priority patent/DE212020000672U1/de
Publication of WO2022057016A1 publication Critical patent/WO2022057016A1/zh

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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L1/00Enclosures; Chambers
    • B01L1/52Transportable laboratories; Field kits
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L1/00Enclosures; Chambers
    • B01L1/04Dust-free rooms or enclosures
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B60VEHICLES IN GENERAL
    • B60PVEHICLES ADAPTED FOR LOAD TRANSPORTATION OR TO TRANSPORT, TO CARRY, OR TO COMPRISE SPECIAL LOADS OR OBJECTS
    • B60P3/00Vehicles adapted to transport, to carry or to comprise special loads or objects
    • B60P3/14Vehicles adapted to transport, to carry or to comprise special loads or objects the object being a workshop for servicing, for maintenance, or for carrying workmen during work
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B60VEHICLES IN GENERAL
    • B60PVEHICLES ADAPTED FOR LOAD TRANSPORTATION OR TO TRANSPORT, TO CARRY, OR TO COMPRISE SPECIAL LOADS OR OBJECTS
    • B60P3/00Vehicles adapted to transport, to carry or to comprise special loads or objects
    • B60P3/32Vehicles adapted to transport, to carry or to comprise special loads or objects comprising living accommodation for people, e.g. caravans, camping, or like vehicles
    • B60P3/34Vehicles adapted to transport, to carry or to comprise special loads or objects comprising living accommodation for people, e.g. caravans, camping, or like vehicles the living accommodation being expansible, collapsible or capable of rearrangement
    • EFIXED CONSTRUCTIONS
    • E04BUILDING
    • E04BGENERAL BUILDING CONSTRUCTIONS; WALLS, e.g. PARTITIONS; ROOFS; FLOORS; CEILINGS; INSULATION OR OTHER PROTECTION OF BUILDINGS
    • E04B1/00Constructions in general; Structures which are not restricted either to walls, e.g. partitions, or floors or ceilings or roofs
    • E04B1/343Structures characterised by movable, separable, or collapsible parts, e.g. for transport
    • E04B1/34305Structures characterised by movable, separable, or collapsible parts, e.g. for transport telescopic
    • E04B1/3431Structures characterised by movable, separable, or collapsible parts, e.g. for transport telescopic with only one level of nesting

Definitions

  • the present application relates to the field of virus detection, and in particular, to a vehicle-mounted pull-out detection laboratory for virus detection and a vehicle having the vehicle-mounted pull-out detection laboratory.
  • virus detection laboratories used for virus detection and research have also experienced serious shortages.
  • biosafety laboratories used for virus detection and research have also experienced serious shortages.
  • medical staff need to quickly go to the site to collect relevant samples (relevant samples can include human body, animal, environment, etc.), and then send the relevant samples to biosafety
  • the protection laboratory (testing laboratory) conducts the detection and identification of potential biological risk factors (pathogens, toxins, etc.) to effectively support the rapid response to the epidemic on site.
  • a container is used to temporarily build a testing laboratory on site.
  • the testing laboratory occupies a large area.
  • the existing testing laboratory cannot be transported by air, and the testing laboratory cannot quickly reach the outbreak site.
  • the present application aims to solve one of the above-mentioned technical problems in the prior art at least to a certain extent.
  • the present application proposes a vehicle-mounted pull-out testing laboratory for virus detection, which can quickly build a testing laboratory in an epidemic situation, save time for building a testing laboratory, and is beneficial to the epidemic situation.
  • the on-board pull-out testing laboratory is not in use, the floor space of the on-board pull-out testing laboratory can be reduced.
  • the present application also proposes a vehicle having the above-mentioned vehicle-mounted pull-out detection laboratory for virus detection.
  • the vehicle-mounted pull-out detection laboratory for virus detection includes: an equipment compartment; a support frame body, the equipment compartment is arranged in the support frame body, and the support frame body
  • the supporting feet have a ground-off state and a ground-supporting state; a plurality of experimental chambers are connected to the support frame body in a drawable manner.
  • the vehicle-mounted pull-out testing laboratory for virus detection through the cooperation between the equipment warehouse and the pull-out experimental warehouse, when a sudden infectious disease outbreak occurs in a certain place, the vehicle can quickly pull the vehicle-mounted pull-out testing laboratory to the test laboratory. Transported to the epidemic area, the testing laboratory can be quickly built in the epidemic area, which can save the time of building the testing laboratory, and the testing laboratory can be put into use quickly, which can shorten the information time for testing and identifying relevant samples, which is conducive to the prevention of the epidemic. control. Moreover, when the vehicle-mounted pull-out testing laboratory is not in use, the footprint of the vehicle-mounted pull-out inspection laboratory can be reduced.
  • the support feet are adapted to expand and contract laterally and longitudinally.
  • the supporting feet include: horizontal telescopic feet and vertical telescopic feet, the horizontal telescopic feet are suitable for laterally extending out of the support frame body or laterally retracting into the support frame body, and the vertical telescopic feet are provided with On the lateral telescopic feet, and the vertical telescopic feet are suitable for vertical expansion and contraction, so that the supporting feet are in the ground-off state or the ground-supporting state.
  • a drive device is provided in the support frame, and the drive device is adapted to drive the experimental chamber to at least partially withdraw the support frame body or retract the support frame body.
  • the driving device includes: a driving cylinder and a driving rod, the driving cylinder is suitable for driving the driving rod to reciprocate, and the driving rod is connected with the experiment chamber.
  • each of the experimental chambers is driven by the corresponding drive rod.
  • the plurality of experimental chambers include: a first experimental chamber located on a first side of the equipment chamber and a second experimental chamber located on a second side of the equipment chamber, the first experimental chamber and the second experimental compartment are arranged along the length direction of the equipment compartment.
  • the first experimental chamber includes: a first sample receiving and preparation area and an amplification area
  • the second experimental chamber includes: a reagent preparation area and a second sample receiving and preparation area, the reagent preparation area and the A first transfer window is arranged between the first sample receiving and preparing areas, a second transfer window is arranged between the first sample receiving and preparing area and the second sample receiving and preparing area, and the second sample receiving and preparing area is A third transfer window is provided between the region and the amplification region.
  • the equipment compartment includes an intermediate partition wall, the first side space of the intermediate partition wall is communicated with the first experimental warehouse, and the second side space of the intermediate partition wall is communicated with the second experimental warehouse,
  • the first transfer window, the second transfer window, and the third transfer window are all disposed on the intermediate partition wall.
  • the reagent preparation area is a positive pressure environment
  • the first sample reception preparation area, the amplification area, and the second sample reception preparation area are all negative pressure environments, and all The negative pressure in the amplification region is the strongest.
  • a plurality of buffer rooms are provided in the support frame, and each of the buffer rooms has an outer door that can selectively communicate with the outside world and an inner door that can selectively communicate with the corresponding experimental chamber. door.
  • the vehicle-mounted pull-out testing laboratory further includes: an air conditioner, the air conditioner is used to adjust the temperature and humidity of each of the experimental chambers, the air conditioner includes a plurality of indoor units, a plurality of Each of the indoor units is in one-to-one correspondence with a plurality of the experimental chambers.
  • the vehicle-mounted pull-out testing laboratory further includes: a fresh air filtration system
  • the fresh air filtration system includes: an air supply system and an air exhaust system
  • the air supply system is provided with a fresh air fan and is used for Air is supplied into the experimental chamber
  • the air exhaust system is used to discharge the gas in the experimental chamber to the vehicle-mounted pull-out testing laboratory.
  • the vehicle-mounted pull-out testing laboratory has an intelligent cabin pressure control system, and the fresh air filtering system is electrically connected to the intelligent cabin pressure control system.
  • the temperature and humidity of the experimental chamber are adjusted by an air conditioner and driven and pulled by the driving device, an equipment room is arranged in the support frame, the air conditioner outdoor unit of the air conditioner, the The drive control cabinet of the drive device and the cabin pressure control cabinet of the intelligent cabin pressure control system are arranged in the equipment room.
  • a vehicle according to another embodiment of the present application includes: a vehicle body and the above-mentioned vehicle-mounted pull-out detection laboratory for virus detection.
  • the vehicle-mounted pull-out testing laboratory has a vehicle-mounted state placed on the vehicle body and an off-vehicle state separated from the vehicle body.
  • a detachable connection is achieved between the support frame body and the vehicle body through fasteners.
  • Fig. 1 is the three-dimensional schematic diagram that the vehicle-mounted pull-out detection laboratory used for virus detection is located on the vehicle body;
  • Fig. 2 is the frame schematic diagram of the vehicle-mounted pull-out detection laboratory used for virus detection
  • Figure 3 is a top view of the vehicle-mounted pull-out detection laboratory used for virus detection on the vehicle body
  • Figure 4 is a perspective view of the on-board pull-out testing laboratory located on the vehicle body after removing some equipment;
  • Figure 5 is a perspective view of the on-board pull-out testing laboratory located on the vehicle body after the equipment is configured;
  • FIG. 6 is a schematic cross-sectional view of a vehicle-mounted pull-out testing laboratory.
  • Vehicle 100 vehicle-mounted pull-out testing laboratory 10, equipment compartment 1, intermediate partition wall 11, support frame 2, equipment room 21, fixed arm 22, bolt holes 221, first experimental compartment 31, first sample receiving and preparation area 311, amplification area 312, second experimental chamber 32, reagent preparation area 321, second sample receiving and preparation area 322, support feet 4, horizontal telescopic feet 41, vertical telescopic feet 42, driving device 5, driving cylinder 51, Drive rod 52, first transfer window 61, second transfer window 62, third transfer window 63, outer door 71, inner door 72, first buffer room 73, amplification buffer room 74, reagent buffer room 75, second buffer Room 76 , vehicle body 20 , generator 30 .
  • first and second are only used for descriptive purposes, and should not be construed as indicating or implying relative importance or implying the number of indicated technical features. Thus, a feature defined as “first” or “second” may expressly or implicitly include one or more of that feature.
  • plurality means at least two, such as two, three, etc., unless expressly and specifically defined otherwise.
  • the terms “installed”, “connected”, “connected”, “fixed” and other terms should be understood in a broad sense, for example, it may be a fixed connection or a detachable connection It can be a mechanical connection, an electrical connection or can communicate with each other; it can be directly connected, or it can be indirectly connected through an intermediate medium, it can be the internal communication between two elements or the interaction relationship between the two elements.
  • installed e.g., it may be a fixed connection or a detachable connection
  • it can be a mechanical connection, an electrical connection or can communicate with each other; it can be directly connected, or it can be indirectly connected through an intermediate medium, it can be the internal communication between two elements or the interaction relationship between the two elements.
  • the vehicle-mounted pull-out detection laboratory 10 for virus detection will be described in detail below with reference to FIGS. 1 to 6 .
  • a vehicle-mounted pull-out detection laboratory 10 for virus detection includes an equipment compartment 1 , a support frame 2 and a plurality of experimental compartments.
  • the equipment compartment 1 is arranged in the support frame 2, and the equipment compartment 1 can store medical supplies such as medical equipment, office supplies and office furniture.
  • the supporting frame body 2 has a plurality of supporting feet 4, and the supporting legs 4 have a ground-off state and a ground-supporting state.
  • the supporting feet 4 When the supporting feet 4 are in the ground-supporting state, the supporting frame body 2 can be stably supported on the ground by the supporting feet 4.
  • there is a space between the support frame body 2 and the ground so that the vehicle body 20 of the vehicle 100 can drive into the space below the support frame body 2.
  • the support feet 4 are adjusted to In the off-ground state, the body 20 of the vehicle 100 can carry the vehicle-mounted pull-out testing laboratory 10 to another location.
  • a plurality of experimental chambers can be connected to the support frame body 2 in a drawable manner.
  • a plurality of experimental chambers can be drawn out from the support frame body 2 , and can also be retracted into the support frame body 2 .
  • the space in the vehicle-mounted pull-out testing laboratory 10 is relatively large, and at this time, medical personnel can enter the experimental chamber to complete the detection work.
  • the test chamber is retracted into the support frame 2 , the test chamber can be stacked on the equipment chamber 1 .
  • the entire vehicle-mounted pull-out testing laboratory 10 is small in size, which is convenient for transporting the vehicle-mounted pull-out test laboratory 10 .
  • the pull-out test chamber further shortens the construction time of the vehicle-mounted pull-out testing laboratory 10 .
  • the vehicle-mounted pull-out testing laboratory 10 as a kind of vehicle-mounted testing laboratory, can be constructed quickly.
  • the vehicle-mounted pull-out testing laboratory 10 may further include a generator 30, and the generator 30 may provide power for devices that require electrical energy, such as medical equipment, office supplies, and office furniture.
  • medical equipment can include: medical refrigerators, automated sample preparation systems, palm centrifuges, vortex shakers, ultra-clean workbenches, biological safety cabinets, QPCR instruments, high-speed centrifuges, plate centrifuges, barcode printers , Mobile UV car, sterilizer, autoclave, etc.
  • Office supplies can include: computers, etc.
  • Office furniture can include: wash basins, equipment tables, etc.
  • the outbreak of the epidemic is sudden. Taking the outbreak of the new coronavirus as an example, it is difficult to predict which city the epidemic will break out in. Once the epidemic breaks out, it is necessary to quickly build a nucleic acid testing laboratory in the place where the epidemic broke out. . If an epidemic breaks out in a certain area, the vehicle 100 carries the vehicle-mounted pull-out testing laboratory 10 and drives to the epidemic site, and pulls the test chamber to the pull-out position. Multiple experimental warehouses that meet the needs of use. Multiple experimental warehouses can be used for nucleic acid detection. After the experimental warehouse is set up, medical equipment, office supplies, office furniture and other medical supplies are arranged and designed according to the specifications to achieve the height of the space.
  • the experimental compartment can be put into use.
  • the vehicle 100 will quickly transport the vehicle-mounted testing laboratory 10 to the epidemic area, which can quickly build a new type of coronavirus in the epidemic area.
  • Out of the testing laboratory can save the time of building the testing laboratory, and the testing laboratory can be put into use quickly, which can shorten the information time for testing and identifying relevant samples, which is conducive to the prevention and control of the epidemic.
  • the vehicle-mounted pull-out testing laboratory 10 is used.
  • the reduced volume of the vehicle-mounted pull-out testing laboratory 10 can reduce the footprint of the vehicle-mounted pull-out testing laboratory 10 , thereby facilitating the storage of the vehicle-mounted pull-out testing laboratory 10 .
  • the vehicle-mounted pull-out testing laboratory 10 of the present application can be transported by the vehicle 100 to the place where the epidemic occurs at any time, and can be quickly put into use in the epidemic situation, so as to achieve the effect of emergency use of the vehicle-mounted pull-out test laboratory 10.
  • the vehicle-mounted pull-out test laboratory 10 can Applied in different sites, the vehicle pull-out testing laboratory 10 has low requirements for land use, and can quickly build a testing laboratory in the epidemic area, thereby improving the construction efficiency of the testing laboratory. In addition, after the epidemic, the on-board pull-out testing laboratory 10 can be transformed into other functions for use.
  • the vehicle-mounted pull-out testing laboratory 10 for virus detection through the cooperation between the equipment compartment 1 and the pull-out experimental compartment, when a sudden infectious disease outbreak occurs in a certain place, compared with the prior art, the vehicle 100
  • the vehicle-mounted pull-out testing laboratory 10 can be quickly transported to the epidemic area, which can quickly build a testing laboratory in the epidemic area, which can save the time of building the testing laboratory, and the testing laboratory can be quickly put into use, which can shorten the detection and identify the relevant
  • the information time of the sample is conducive to the prevention and control of the epidemic.
  • the footprint of the vehicle-mounted pull-out testing laboratory 10 can be reduced.
  • the support feet 4 are adapted to expand and contract in the transverse and longitudinal directions.
  • the supporting feet 4 include: horizontal telescopic feet 41 and vertical telescopic feet 42 , and the horizontal telescopic feet 41 are suitable for laterally extending the support frame body 2 or laterally retracting the support frame body 2 Inside, the vertical telescopic feet 42 are arranged on the horizontal telescopic feet 41 , and the vertical telescopic feet 42 are adapted to extend and retract vertically, so that the supporting feet 4 are in a ground-off state or a ground-supporting state.
  • the horizontal telescopic feet 41 can be arranged at the ends of the horizontal telescopic feet 41, so that when the horizontal telescopic feet 41 extend laterally out of the support frame body 2, the vertical telescopic feet 42 are far away from the support frame body 2, and at this time, the vertical
  • the distribution of the plurality of supporting legs 4 is relatively dispersed, and the supporting legs 4 can better support the supporting frame body 2 .
  • the laterally retractable legs 41 are retracted laterally to the support frame body 2 , the storage management of the laterally retractable legs 41 can be realized, and the floor space of the vehicle-mounted pull-out testing laboratory 10 can be reduced.
  • the support frame body 2 is provided with a drive device 5 , and the drive device 5 is adapted to drive the experimental chamber to at least partially withdraw the support frame body 2 or retract the support frame body 2 .
  • the driving device 5 includes a driving cylinder 51 and a driving rod 52, the driving cylinder 51 is adapted to drive the corresponding driving rod 52 to reciprocate, and the driving rod 52 is connected with the experiment chamber.
  • the experimental chamber can be pulled out from the supporting frame body 2, and when the driving rod 52 is retracted relative to the driving cylinder 51, the experimental chamber can be retracted into the supporting frame body 2.
  • the experimental bin can be stopped at any position within the range of travel, so it is convenient to adjust the pulling degree of the experimental bin according to the size of the surrounding space.
  • each experimental chamber is driven by a corresponding driving rod 52 . Since the experimental chamber has a certain weight, in practical application, the same experimental chamber can be driven by a plurality of driving rods 52 to realize the pulling action.
  • the driving cylinder 51 may be a hydraulic cylinder, and the driving rod 52 may be a hydraulic rod driven and moved by the hydraulic cylinder; in other optional embodiments, the driving cylinder 51 may be a pneumatic cylinder, and the driving rod 52 may be It is a pneumatic rod that is driven and moved by a pneumatic cylinder. Both the hydraulic cylinder and the pneumatic cylinder can provide a large driving force to realize the pulling action of the experimental chamber.
  • the plurality of experimental compartments include: a first experimental compartment 31 located on the first side 101 of the equipment compartment 1 and a second experimental compartment 32 located on the second side 102 of the equipment compartment 1.
  • the first experimental compartment 31 and the second experimental chamber 32 are arranged along the length direction of the equipment chamber 1 .
  • the number of the first experimental bins 31 may be one or more, and the number of the second experimental bins 32 may be one or more.
  • the plurality of first test chambers 31 can be arranged in sequence along the length direction of the equipment chamber 1, and two adjacent first test chambers 31 are separated by a first partition wall 313, In order to make each first experimental chamber 31 an independent experimental chamber with good air tightness.
  • the plurality of second test chambers 32 can be arranged in sequence along the length direction of the equipment chamber 1, and two adjacent second test chambers 32 are separated by a second partition wall 323, In order to make each second experimental chamber 32 an independent experimental chamber with good air tightness.
  • FIG. 2 only shows the frame structure, in practical application, the frame structure will cover the frame with a plate-like structure with good sealing performance, so as to form an experimental chamber with good air tightness.
  • the first experimental chamber 31 includes: a first sample receiving and preparing area 311 and an amplification area 312
  • the second experimental chamber 32 includes: a reagent preparation area 321 and a second sample receiving and preparation area 322, a first transfer window 61 is provided between the reagent preparation area 321 and the first sample receiving and preparation area 311, and the first sample receiving and preparation area
  • a second transfer window 62 is disposed between 311 and the second sample receiving and preparing area 322
  • a third transfer window 63 is disposed between the second sample receiving and preparing area 322 and the amplification area 312 .
  • first transfer window 61 when the first transfer window 61 is open, objects can be transferred between the reagent preparation area 321 and the first sample receiving preparation area 311 through the first transfer window 61 , and when the first transfer window 61 is closed, the reagent preparation area 321 It is spaced apart from the first sample receiving and preparing area 311; when the second transfer window 62 is opened, objects can be transferred between the first sample receiving and preparing area 311 and the second sample receiving and preparing area 322 through the second transfer window 62.
  • the first sample receiving and preparing area 311 is spaced apart from the second sample receiving and preparing area 322; when the third transfer window 63 is opened, the second sample receiving and preparing area 322 and Objects are transferred between the amplification regions 312 , and when the third transfer window 63 is closed, the second sample receiving and preparation region 322 is spaced apart from the amplification region 312 .
  • the reagent preparation area 321 is used for reagent preparation, storage and dispensing.
  • the first sample receiving and preparing area 311 and the second sample receiving and preparing area 322 can be used for sample receiving, storage, unpacking, inactivation, sample transfer, RNA Extraction, in one embodiment of the present application, the first sample receiving and preparing area 311 is used as a sample receiving area for sample receiving, storage, unpacking, and inactivation, and the second sample receiving and preparing area 322 is used as The sample preparation area is used for sample transfer and RNA extraction, and the amplification area 312 is used to amplify the sample.
  • the path of the object in the vehicle-mounted pull-out detection laboratory 10 is the reagent preparation area 321 ⁇ the first sample receiving and preparing area 311 ⁇ the second sample receiving and preparing area 322 ⁇ the amplification area 312 .
  • the reagents in the reagent preparation area 321 can be transferred to the first sample receiving and preparing area 311 through the first transfer window 61
  • the reagents in the first sample receiving and preparing area 311 can be transferred to the second sample receiving and preparing area through the second transfer window 62 .
  • the reagent in the second sample receiving and preparing area 322 can be transferred to the amplification area 312 through the third transfer window 63, so as to realize the object in the reagent preparing area 321, the first sample receiving and preparing area 311, the second sample receiving and preparing area Transfer between zone 322, amplification zone 312.
  • the first sample receiving and preparing area 311 and the amplification area 312 are separated by a first partition wall 313
  • the reagent preparation area 321 and the second sample receiving and preparing area 322 are separated by a second partition wall 323 separated.
  • the length of the first sample receiving and preparation area 311 is greater than the length of the amplification area 312
  • the length of the second sample receiving and preparation area 322 is greater than that of the reagent preparation area 321 .
  • the second partition wall 323 is directly opposite to the first sample receiving and preparing area 311 , so that the first sample receiving and preparing area 311 can transfer objects to the reagent preparing area 321 through the first transfer window 61 , and the first sample receiving and preparing area 321 311 can realize the transfer of objects with the second sample receiving preparation area 322 through the second transfer window 62 .
  • the transfer box includes an inner door of the transfer box and an outer door of the transfer box, and the transfer box can adopt intelligent interaction technology, so that the inner door of the transfer box and the outer door of the transfer box form an intelligent interlock structure, so as to ensure that the inner door of the transfer box and the outer door of the transfer box form an intelligent interlocking structure.
  • the outer doors of the transfer box cannot be opened at the same time.
  • the transfer box may be constructed as a single-level door structure.
  • the equipment compartment 1 includes an intermediate partition wall 11, the first side space 12 of the intermediate partition wall 11 is communicated with the first experimental warehouse 31, and the second side space 13 of the intermediate partition wall 11 is connected to The second experimental chamber 32 is connected, and the first transfer window 61 , the second transfer window 62 , and the third transfer window 63 are all disposed on the intermediate partition wall 11 .
  • Each experimental chamber may be configured as a rectangular parallelepiped structure, and has an opening that is open toward the middle partition wall 11 . In this way, a closed space can be defined between the five side walls of the experimental chamber and the intermediate partition wall 11 .
  • the support frame body 2 can be constructed as a closed plate structure with openings only at the position of the experimental chamber, so as to ensure good air tightness in the vehicle-mounted pull-out testing laboratory 10 .
  • the reagent preparation area 321 is a positive pressure environment
  • the first sample reception preparation area 311 , the amplification area 312 , and the second sample reception preparation area 322 are all negative pressure environments
  • the amplification area 312 has a negative pressure the strongest.
  • the pressure within the first sample-receiving preparation zone 311 may be equal or approximately equal to the pressure in the second sample-receiving preparation zone 322 .
  • the pressures of the first sample receiving and preparing area 311 , the amplification area 312 , and the second sample receiving and preparing area 322 are all lower than atmospheric pressure.
  • this setting can prevent the pathogens, toxins and other samples in the first sample receiving and preparing area 311 , the amplification area 312 , and the second sample receiving and preparing area 322 from moving out.
  • the vehicle-mounted pull-out testing laboratory 10 can prevent pathogens, toxins and other samples from contaminating the environment, and can also prevent pathogens, toxins, etc. from infecting others.
  • the pressure of the reagent preparation area 321 is higher than atmospheric pressure, so that pathogens, toxins and other objects in the external environment can be prevented from flowing into the reagent preparation area 321 .
  • each buffer room has an outer door 71 that can selectively communicate with the outside world and an inner door 72 that can selectively communicate with the corresponding experimental chamber. . It can enter the corresponding experimental chamber through each buffer room.
  • a buffer space is formed in the buffer room, and the pressure in the buffer room can be different from the corresponding experimental chamber, so that a protective barrier can be formed in the buffer room.
  • the medical staff opens the outer door 71, they first enter the buffer space, and then enter the corresponding experimental chamber through the inner door 72.
  • the pressure in the buffer space can be greater than the atmospheric pressure, thereby preventing dust, bacteria and other substances in the external environment from entering the experimental chamber.
  • the experimental chamber can be well sealed.
  • the outer door 71 and the inner door 72 can be constructed in the form of a zipper door, an opening and closing door, a magic glue door, and the like.
  • the buffer room includes: a first buffer room 73, an amplification buffer room 74, a reagent buffer room 75, and a second buffer room 76.
  • the first buffer room 73 is suitable for receiving and preparing the first sample
  • the area 311 can be selectively connected
  • the amplification buffer room 74 is suitable for selectively connecting with the amplification area 312
  • the reagent buffer room 75 is suitable for selectively connecting with the reagent preparation area 321
  • the second buffer room 76 is suitable for receiving and preparing the second sample.
  • Zone 322 can be optionally connected.
  • the vehicle-mounted pull-out testing laboratory 10 further includes an air conditioner, which is used to adjust the temperature and humidity of each experimental chamber. By setting the air conditioner, the temperature and humidity of each experimental chamber can be maintained within an appropriate range.
  • the air conditioner includes a plurality of indoor units, and the plurality of indoor units are in one-to-one correspondence with the plurality of experimental chambers.
  • the vehicle-mounted pull-out testing laboratory 10 also includes: a fresh air filtration system.
  • the fresh air filtration system includes: an air supply system and an exhaust air system.
  • the air supply system is provided with a fresh fan and a filter device, and the air supply system is used to supply air to the experimental chamber.
  • the fresh air fan and the filter device purify the gas, and the purified gas enters the experimental chamber, thereby ensuring that the gas entering the experimental chamber is clean.
  • the exhaust system is used to discharge the gas in the experimental chamber out of the vehicle-mounted pull-out testing laboratory 10 .
  • the exhaust system can also be provided with a fresh fan and a filter device, and the exhaust system is used to filter the gas in the experimental chamber and discharge it out of the vehicle-mounted pull-out testing laboratory 10 .
  • each experimental chamber is correspondingly set with one air supply system and one air exhaust system, so that the air in each experimental chamber does not interfere with each other.
  • the vehicle-mounted pull-out testing laboratory 10 has an intelligent cabin pressure control system, and the fresh air filter system is electrically connected with the intelligent cabin pressure control system.
  • the intelligent cabin pressure control system can adjust the air supply and exhaust systems to maintain the specific required pressure in each experimental chamber.
  • the temperature and humidity of the experimental chamber are regulated by the air conditioner and driven and pulled by the drive device 5.
  • the support frame 2 is provided with an equipment room 21, the air conditioner outdoor unit of the air conditioner, the drive control cabinet of the drive device 5 and the intelligent cabin pressure control system.
  • the cabin pressure control cabinet is arranged in the equipment room 21 , thereby ensuring that the experiment cabin is clean and free of other auxiliary equipment, and at the same time, the structure of the vehicle-mounted pull-out testing laboratory 10 is more compact.
  • a vehicle 100 includes: a vehicle body 20 and the vehicle-mounted pull-out detection laboratory 10 for virus detection in the above embodiment.
  • the vehicle-mounted pull-out testing laboratory 10 has a vehicle-mounted state placed on the vehicle body 20 and an off-vehicle state separated from the vehicle body 20 .
  • a detachable connection is achieved between the support frame body 2 and the vehicle body 20 through fasteners.
  • the support frame body 2 is provided with a fixed support arm 22, the fixed support arm 22 is provided with a bolt hole 221, and the bolt fastener is suitable for passing through the bolt hole 221 and then fastened to the vehicle body 20,
  • the vehicle-mounted pull-out testing laboratory 10 is in the vehicle-mounted state, which can also prevent the vehicle-mounted pull-out testing laboratory 10 from slipping off the vehicle body 20 when the vehicle 100 is running.
  • the vehicle body 20 can be driven away from the bottom of the support frame body 2. In this way, the on-board pull-out testing laboratory 10 and the vehicle body 20 are in the off-vehicle state, and the vehicle body 20 can be used for transporting other goods or other experiments. room, which is conducive to the rational allocation of energy.
  • the vehicle-mounted pull-out testing laboratory 10 can be carried to a designated location, so as to meet the usage requirements in the epidemic area.
  • references to the terms “one embodiment,” “some embodiments,” “example,” “specific example,” or “some examples”, etc. means a specific feature described in connection with the embodiment or example, A structure, material, or feature is included in at least one embodiment or example of the present application.
  • schematic representations of the above terms are not necessarily directed to the same embodiment or example.
  • the particular features, structures, materials or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
  • those skilled in the art may combine and combine the different embodiments or examples described in this specification.

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Abstract

一种用于病毒检测的车载抽拉检测实验室(10)以及车辆(100),该车载抽拉检测实验室(10)包括:设备仓(1);支撑架体(2),设备仓(1)设置于支撑架体(2)内,支撑架体(2)具有多个撑脚(4),撑脚(4)具有离地状态和撑地状态;多个实验仓(31,32),多个实验仓(31,32)可抽拉地连接于支撑架体(2)。

Description

用于病毒检测的车载抽拉检测实验室以及车辆
相关申请的交叉引用
本申请要求申请日为2020年9月15日、申请号为202022007754.3、专利申请名称为“用于病毒检测的车载抽拉检测实验室以及车辆”的优先权。
技术领域
本申请涉及病毒检测领域,具体而言,涉及一种用于病毒检测的车载抽拉检测实验室以及具有该车载抽拉检测实验室的车辆。
背景技术
2020年初我国大范围疫情爆发后,除了对防疫医院、方舱医院、隔离场所的巨大需求外,用于病毒检测及研究的病毒检测实验室(或生物安全实验室)也出现了严重不足的情况。出现突发传染病疫情或相关事件时,例如:出现新型冠状病毒疫情时,医护人员需要迅速去现场采集相关样本(相关样本可以包括人体、动物、环境等),然后将相关样本送至生物安全防护实验室(检测实验室)进行潜在生物危险因子(病原体、毒素等)检测与鉴别,以有效支持现场快速应对疫情。
当某地出现突发传染病疫情时,当病毒疫情大规模爆发时,传统现有的病毒检测实验室或生物安全实验室显然无法满足灵活且及时的搭建需求。相关技术中,采用集装箱在现场临时搭建检测实验室,检测实验室不使用时,检测实验室占地面积大,并且,现有的检测实验室不可空运,检测实验室不能快速到达疫情发生地。同时,通过临时搭建检测实验室耗费时间长,检测实验室不能快速投入使用,容易延长检测、鉴别出相关样本的信息时间,不利于疫情的防控。
公开内容
本申请旨在至少在一定程度上解决现有技术中的上述技术问题之一。为此,本申请提出一种用于病毒检测的车载抽拉检测实验室,该车载抽拉检测实验室能够在疫情地快速搭建出检测实验室,可以节省搭建检测实验室时间,有利于疫情的防控,并且,车载抽拉检测实验室不使用时,能够减小车载抽拉检测实验室的占地面积。
本申请还提出了一种具有上述用于病毒检测的车载抽拉检测实验室的车辆。
根据本申请实施例的用于病毒检测的车载抽拉检测实验室包括:设备仓;支撑架体, 所述设备仓设置于所述支撑架体内,所述支撑架体具有多个撑脚,所述撑脚具有离地状态和撑地状态;多个实验仓,多个所述实验仓可抽拉地连接于所述支撑架体。
根据本申请实施例的用于病毒检测的车载抽拉检测实验室,通过设备仓和抽拉式实验仓配合,当某地出现突发传染病疫情时,车辆可将车载抽拉检测实验室快速运送至疫情地,能够在疫情地快速建出检测实验室,可以节省搭建检测实验室时间,检测实验室能快速投入使用,从而可以缩短检测、鉴别出相关样本的信息时间,有利于疫情的防控。并且,车载抽拉检测实验室不使用时,能够减小车载抽拉检测实验室的占地面积。
根据本申请的一些实施例,所述撑脚适于沿横向和纵向伸缩。
具体地,所述撑脚包括:横向伸缩脚和竖向伸缩脚,所述横向伸缩脚适于横向伸出所述支撑架体或横向缩回所述支撑架体内,所述竖向伸缩脚设置在所述横向伸缩脚上,且所述竖向伸缩脚适于沿竖向伸缩,以使所述撑脚处于所述离地状态或所述撑地状态。
根据本申请的一些实施例,所述支撑架体内设置有驱动装置,所述驱动装置适于驱动所述实验仓至少部分地抽出所述支撑架体或者缩回所述支撑架体。
具体地,所述驱动装置包括:驱动缸和驱动杆,所述驱动缸适于驱动所述驱动杆往复移动,所述驱动杆与所述实验仓相连接。
可选地,所述驱动杆为多个,每个所述实验仓由对应的所述驱动杆驱动。
根据本申请的一些实施例,多个所述实验仓包括:位于所述设备仓第一侧的第一实验仓以及位于所述设备仓第二侧的第二实验仓,所述第一实验仓和所述第二实验仓均沿所述设备仓的长度方向设置。
具体地,所述第一实验仓包括:第一样本接收制备区以及扩增区,所述第二实验仓包括:试剂准备区以及第二样本接收制备区,所述试剂准备区与所述第一样本接收制备区之间设置有第一传递窗,所述第一样本接收制备区与所述第二样本接收制备区之间设置有第二传递窗,所述第二样本接收制备区与所述扩增区之间设置有第三传递窗。
进一步地,所述设备仓包括中间分隔壁,所述中间分隔壁的第一侧空间与所述第一实验仓连通,所述中间分隔壁的第二侧空间与所述第二实验仓连通,所述第一传递窗、所述第二传递窗、所述第三传递窗均设置在所述中间分隔壁上。
根据本申请的一些实施例,所述试剂准备区为正压环境,所述第一样本接收制备区、所述扩增区、所述第二样本接收制备区均为负压环境,且所述扩增区的负压最强。
根据本申请的一些实施例,所述支撑架体内设置有多个缓冲间,每个所述缓冲间具有与外界可选择性连通的外门以及与对应的所述实验仓可选择性连通的内门。
根据本申请的一些实施例,所述车载抽拉检测实验室还包括:空调器,所述空调器用于调节每个所述实验仓的温度和湿度,所述空调器包括多个室内机,多个所述室内机与多 个所述实验仓一一对应。
根据本申请的一些实施例,所述车载抽拉检测实验室还包括:新风过滤系统,所述新风过滤系统包括:送风系统和排风系统,所述送风系统设有新风机且用于向所述实验仓内送风,所述排风系统用于将所述实验仓内的气体排出所述车载抽拉检测实验室。
根据本申请的一些实施例,所述车载抽拉检测实验室具有智能舱压控制系统,所述新风过滤系统与所述智能舱压控制系统电连接。
根据本申请的一些实施例,所述实验仓由空调器调节温度和湿度且由所述驱动装置驱动抽拉,所述支撑架体内设置有设备间,所述空调器的空调室外机、所述驱动装置的驱动控制柜和所述智能舱压控制系统的舱压控制柜设置在所述设备间内。
根据本申请另一方面实施例的车辆,包括:车体和上述的用于病毒检测的车载抽拉检测实验室。
具体地,所述车载抽拉检测实验室具有置于所述车体上的车载状态以及与所述车体分离的离车状态。
可选地,所述支撑架体与所述车体之间通过紧固件实现可拆卸式连接。
本申请的附加方面和优点将在下面的描述中部分给出,部分将从下面的描述中变得明显,或通过本申请的实践了解到。
附图说明
图1是用于病毒检测的车载抽拉检测实验室位于车体上的立体示意图;
图2是用于病毒检测的车载抽拉检测实验室的框架示意图;
图3是用于病毒检测的车载抽拉检测实验室位于车体上的俯视图;
图4是去除部分设备后,车载抽拉检测实验室位于车体上的立体示意图;
图5是配置设备后,车载抽拉检测实验室位于车体上的立体示意图;
图6是车载抽拉检测实验室的截面示意图。
附图标记:
车辆100、车载抽拉检测实验室10、设备仓1、中间分隔壁11、支撑架体2、设备间21、固定支臂22、螺栓孔221、第一实验仓31、第一样本接收制备区311、扩增区312、第二实验仓32、试剂准备区321、第二样本接收制备区322、撑脚4、横向伸缩脚41、竖向伸缩脚42、驱动装置5、驱动缸51、驱动杆52、第一传递窗61、第二传递窗62、第三传递窗63、外门71、内门72、第一缓冲间73、扩增缓冲间74、试剂缓冲间75、第二缓冲间76、车体20、发电机30。
具体实施方式
下面详细描述本申请的实施例,所述实施例的示例在附图中示出,其中自始至终相同或类似的标号表示相同或类似的元件或具有相同或类似功能的元件。下面通过参考附图描述的实施例是示例性的,旨在用于解释本申请,而不能理解为对本申请的限制。
在本申请的描述中,需要理解的是,术语“纵向”、“横向”、“长度”、“宽度”、“厚度”、“上”、“下”、“前”、“后”、“左”、“右”、“竖直”、“水平”、“顶”、“底”、“内”、“外”等指示的方位或位置关系为基于附图所示的方位或位置关系,仅是为了便于描述本申请和简化描述,而不是指示或暗示所指的装置或元件必须具有特定的方位、以特定的方位构造和操作,因此不能理解为对本申请的限制。
此外,术语“第一”、“第二”仅用于描述目的,而不能理解为指示或暗示相对重要性或者隐含指明所指示的技术特征的数量。由此,限定有“第一”、“第二”的特征可以明示或者隐含地包括一个或者更多个该特征。在本申请的描述中,“多个”的含义是至少两个,例如两个,三个等,除非另有明确具体的限定。
在本申请中,除非另有明确的规定和限定,术语“安装”、“相连”、“连接”、“固定”等术语应做广义理解,例如,可以是固定连接,也可以是可拆卸连接,或成一体;可以是机械连接,也可以是电连接或可以互相通讯;可以是直接相连,也可以通过中间媒介间接相连,可以是两个元件内部的连通或两个元件的相互作用关系。对于本领域的普通技术人员而言,可以根据具体情况理解上述术语在本申请中的具体含义。
下面结合图1-图6详细描述根据本申请实施例的用于病毒检测的车载抽拉检测实验室10。
参照图1-图6所示,根据本申请实施例的用于病毒检测的车载抽拉检测实验室10包括:设备仓1、支撑架体2以及多个实验仓。
设备仓1设置于支撑架体2内,设备仓1内可以存储有医疗设备、办公用品和办公家具等医疗用品。
支撑架体2具有多个撑脚4,撑脚4具有离地状态和撑地状态,当撑脚4处于撑地状态时,支撑架体2可被撑脚4平稳地支撑于地面之上,防止支撑架体2抖动,同时,使得支撑架体2与地面之间具有空间,这样,车辆100的车体20可以驶入支撑架体2的下方空间,此时若再将撑脚4调整为离地状态,则车辆100的车体20可载着车载抽拉检测实验室10转移至另一地点。
多个实验仓可抽拉地连接于支撑架体2。换言之,多个实验仓可从支撑架体2内抽出,也可以缩回到支撑架体2内。当实验仓从支撑架体2内抽出时,车载抽拉检测实验室10内的空间较大,此时,医疗人员可以进入实验仓完成检测工作。当实验仓缩回到支撑架体2 内时,实验仓可堆叠在设备仓1上,此时,整个车载抽拉检测实验室10的体积较小,方便运输车载抽拉检测实验室10。同时,抽拉式的实验仓更加进一步缩短车载抽拉检测实验室10的搭建时间。车载抽拉检测实验室10作为车载检测实验室的一种,可以实现快速搭建。
车载抽拉检测实验室10还可以包括发电机30,发电机30可以为医疗设备、办公用品和办公家具等需要电能的设备供电。
需要说明的是,医疗设备可以包括:医用冷藏箱、自动化样本制备系统、掌式离心机、漩涡振荡仪、超洁工作台、生物安全柜、QPCR仪、高速离心机、板式离心机、条码打印机、移动紫外车、灭菌器、高压灭菌锅等。办公用品可以包括:电脑等。办公家具可以包括:洗手盆、设备桌等。
其中,疫情的爆发是突然性的,以新型冠状病毒疫情爆发是突然性的为例进行说明,疫情在哪个城市爆发难以预估,一旦疫情爆发,就需要在疫情爆发地快速建成核酸检测实验室。如果某个地区爆发疫情,车辆100承载车载抽拉检测实验室10行驶至疫情地,通过抽拉实验仓使实验仓位于拉出位置,在几分钟内,就可在设备仓1的侧面限定出多个满足使用需求的实验仓,多个实验仓可以用于核酸的检测,实验仓设置完成后,根据规范对医疗设备、办公用品和办公家具等医疗用品进行排布设计,以达到空间的高度利用,例如:将对医疗设备、办公用品和办公家具等医疗用品摆放至设备仓1和实验仓的合适位置,摆放完成后,实验仓就可投入使用。与临时搭建的检测实验室或者新建传统建筑的检测实验室相比,当某地出现新型冠状病毒疫情时,车辆100将车载抽拉检测实验室10快速运送至疫情地,能够在疫情地快速建出检测实验室,可以节省搭建检测实验室时间,检测实验室能快速投入使用,从而可以缩短检测、鉴别出相关样本的信息时间,有利于疫情的防控。
并且,车载抽拉检测实验室10使用完成后,将医疗设备、办公用品和办公家具等医疗用品放置于设备仓1,控制实验仓缩回到支撑架体2内,使车载抽拉检测实验室10的体积减小,可以减小车载抽拉检测实验室10的占地面积,从而便于车载抽拉检测实验室10的存放。同时,本申请的车载抽拉检测实验室10可由车辆100随时运送至疫情发生地,能够迅速投入疫情中使用,达到应急使用车载抽拉检测实验室10的效果,车载抽拉检测实验室10可以在不同的场地上应用,车载抽拉检测实验室10对用地基础要求低,可以快速在疫情地建成检测实验室,从而可以提升检测实验室的建成效率。另外,在疫情过后,可以将车载抽拉检测实验室10改造成其他功能进行使用。
根据本申请实施例的用于病毒检测的车载抽拉检测实验室10,通过设备仓1和抽拉式实验仓配合,当某地出现突发传染病疫情时,与现有技术相比,车辆100将车载抽拉检测实验室10快速运送至疫情地,能够在疫情地快速建出检测实验室,可以节省搭建检测实验室时间,检测实验室能快速投入使用,从而可以缩短检测、鉴别出相关样本的信息时间, 有利于疫情的防控。并且,车载抽拉检测实验室10不使用时,能够减小车载抽拉检测实验室10的占地面积。
在具体实施例中,撑脚4适于沿横向和纵向伸缩。
具体而言,参照图1-图2所示,撑脚4包括:横向伸缩脚41和竖向伸缩脚42,横向伸缩脚41适于横向伸出支撑架体2或横向缩回支撑架体2内,竖向伸缩脚42设置在横向伸缩脚41上,且竖向伸缩脚42适于沿竖向伸缩,以使撑脚4处于离地状态或撑地状态。横向伸缩脚41可设置在横向伸缩脚41的端部,这样,当横向伸缩脚41横向伸出支撑架体2时,竖向伸缩脚42距离支撑架体2较远,此时,再将竖向伸缩脚42调整至撑地状态时,多个撑脚4分布较为分散,撑脚4可以更好地支撑该支撑架体2。当横向伸缩脚41横向缩回支撑架体2时,可实现对横向伸缩脚41的收纳管理,能够减小车载抽拉检测实验室10的占地面积。
参照图2所示,支撑架体2内设置有驱动装置5,驱动装置5适于驱动实验仓至少部分地抽出支撑架体2或者缩回支撑架体2。
具体地,驱动装置5包括:驱动缸51和驱动杆52,驱动缸51适于驱动对应的驱动杆52往复移动,驱动杆52与实验仓相连接。这样,当驱动杆52相对于驱动缸51伸出时,实验仓实现从支撑架体2内抽出,当驱动杆52相对于驱动缸51缩回时,实验仓实现缩回到支撑架体2内。实验仓可以在行程范围内的任意位置随停,由此方便根据周围空间大小来调节实验仓的抽拉程度。
可选地,驱动杆52为多个,每个实验仓由对应的驱动杆52驱动。由于实验仓具有一定的重量,因此在实际应用时,同一个实验仓可以由多个驱动杆52驱动实现抽拉动作。
在一些实施例中,驱动缸51可以是液压缸,驱动杆52可以是被液压缸驱动移动的液压杆;在另一些可选的实施例中,驱动缸51可以是气压缸,驱动杆52可以是被气压缸驱动移动的气压杆。液压缸和气压缸均能够提供较大的驱动力,以实现实验仓的抽拉动作。
参照图2-图5所示,多个实验仓包括:位于设备仓1第一侧101的第一实验仓31以及位于设备仓1第二侧102的第二实验仓32,第一实验仓31和第二实验仓32均沿设备仓1的长度方向设置。
第一实验仓31的数量可以是一个或多个,第二实验仓32的数量可以是一个或多个。当第一实验仓31为多个,多个第一实验仓31可沿设备仓1的长度方向依次设置,且相邻两个第一实验仓31之间通过第一分隔壁313分隔开,以使各个第一实验仓31成为气密性良好的独立实验仓。当第二实验仓32为多个,多个第二实验仓32可沿设备仓1的长度方向依次设置,且相邻两个第二实验仓32之间通过第二分隔壁323分隔开,以使各个第二实验仓32成为气密性良好的独立实验仓。
需要说明的是,虽然图2仅示出了框架式结构,但是实际应用时,框架式结构上会用密封性能良好的板状结构来包覆框架,从而形成气密性良好的实验仓。
在图2-图5所示的实施例中,第一实验仓31和第二实验仓32均为两个,第一实验仓31包括:第一样本接收制备区311以及扩增区312,第二实验仓32包括:试剂准备区321以及第二样本接收制备区322,试剂准备区321与第一样本接收制备区311之间设置有第一传递窗61,第一样本接收制备区311与第二样本接收制备区322之间设置有第二传递窗62,第二样本接收制备区322与扩增区312之间设置有第三传递窗63。当传递窗打开时,可以通过传递窗在相邻的两个实验仓之间传递物体,当传递窗关闭时,传递窗将相邻的两个实验仓间隔开,可以避免相邻的两个实验仓之间产生相互污染。
具体而言,第一传递窗61打开时,可以通过第一传递窗61在试剂准备区321与第一样本接收制备区311之间传递物体,第一传递窗61关闭时,试剂准备区321与第一样本接收制备区311间隔开;第二传递窗62打开时,可以通过第二传递窗62在第一样本接收制备区311与第二样本接收制备区322之间传递物体,第二传递窗62关闭时,第一样本接收制备区311与第二样本接收制备区322间隔开;第三传递窗63打开时,可以通过第三传递窗63在第二样本接收制备区322与扩增区312之间传递物体,第三传递窗63关闭时,第二样本接收制备区322与扩增区312间隔开。
试剂准备区321用于试剂准备、储存以及分装,第一样本接收制备区311、第二样本接收制备区322均可用于样本接收、入库、拆包、灭活、样本转板、RNA提取,在本申请的一个实施例中,将第一样本接收制备区311用作样本接收区,用于样本接收、入库、拆包、灭活,将第二样本接收制备区322用作样本制备区,用于样本转板、RNA提取,扩增区312用于对样本进行扩增。此时,物体在车载抽拉检测实验室10内的路径为试剂准备区321→第一样本接收制备区311→第二样本接收制备区322→扩增区312。试剂准备区321内的试剂可以通过第一传递窗61传送至第一样本接收制备区311,第一样本接收制备区311内的试剂可以通过第二传递窗62传送至第二样本接收制备区322,第二样本接收制备区322内的试剂可以通过第三传递窗63传送至扩增区312,从而实现物体在试剂准备区321、第一样本接收制备区311、第二样本接收制备区322、扩增区312之间的传递。
参照图5所示,第一样本接收制备区311与扩增区312之间通过第一分隔壁313分隔开,试剂准备区321与第二样本接收制备区322之间通过第二分隔壁323分隔开。
第一样本接收制备区311的长度大于扩增区312的长度,第二样本接收制备区322的长度大于试剂准备区321的长度。第二分隔壁323与第一样本接收制备区311正对,这样,第一样本接收制备区311可通过第一传递窗61实现与试剂准备区321传递物体,第一样本接收制备区311可通过第二传递窗62实现与第二样本接收制备区322传递物体。
在一些实施例中,传递箱包括传递箱内门和传递箱外门,传递箱可采用智能交互技术,使传递箱内门和传递箱外门形成智能互锁结构,以确保传递箱内门和传递箱外门不能同时打开。
在另一些实施例中,传递箱可构造为单层门结构。
进一步地,参照图2-图6所示,设备仓1包括中间分隔壁11,中间分隔壁11的第一侧空间12与第一实验仓31连通,中间分隔壁11的第二侧空间13与第二实验仓32连通,第一传递窗61、第二传递窗62、第三传递窗63均设置在中间分隔壁11上。
每个实验仓可构造为长方体结构,且具有朝向中间分隔壁11敞开的开口。这样,实验仓的五个侧壁可以与中间分隔壁11之间限定出密闭空间。
支撑架体2可构造为仅在实验仓位置设置开口的密闭板式结构,从而保证车载抽拉检测实验室10内的良好气密性。
在一些实施例中,试剂准备区321为正压环境,第一样本接收制备区311、扩增区312、第二样本接收制备区322均为负压环境,且扩增区312的负压最强。第一样本接收制备区311内的压强可以与第二样本接收制备区322的压强相等或近似相等。试剂准备区321、第一样本接收制备区311、扩增区312、第二样本接收制备区322的压强关系可以是:试剂准备区321>0>第一样本接收制备区311=第二样本接收制备区322>扩增区312。
换言之,第一样本接收制备区311、扩增区312、第二样本接收制备区322的压强均小于大气压强。其中,由于气体从压强大的地方朝向压强小的地方运动,这样设置能够防止第一样本接收制备区311、扩增区312、第二样本接收制备区322内的病原体、毒素等样本运动出车载抽拉检测实验室10,可以避免病原体、毒素等样本污染环境,也可以避免病原体、毒素等传染给其他人。试剂准备区321的压强大于大气压强,由此能够避免外界环境中的病原体、毒素等物体流入试剂准备区321。
参照图3-图5所示,支撑架体2内设置有多个缓冲间,每个缓冲间具有与外界可选择性连通的外门71以及与对应的实验仓可选择性连通的内门72。可通过各个缓冲间进入对应的实验仓内。缓冲间内形成缓冲空间,缓冲间的压强可以与对应的实验仓有所区别,这样,缓冲间处可以形成一道防护屏障。医疗工作人员打开外门71首先进入缓冲空间,再经内门72进入对应的实验仓内,缓冲空间的压强可大于大气压强,由此可以防止外界环境中的灰尘、细菌等物质进入实验仓,从而可以使实验仓具有很好的密封性。外门71和内门72可以构造为拉链门、开合门、魔术粘门等形式。
参照图3-图5所示,缓冲间包括:第一缓冲间73、扩增缓冲间74、试剂缓冲间75、第二缓冲间76,第一缓冲间73适于与第一样本接收制备区311可选择连通,扩增缓冲间74适于与扩增区312可选择连通,试剂缓冲间75适于与试剂准备区321可选择连通,第 二缓冲间76适于与第二样本接收制备区322可选择连通。
车载抽拉检测实验室10还包括:空调器,空调器用于调节每个实验仓的温度和湿度,通过设置空调器,能够使各个实验仓的温度和湿度保持在适宜范围内。空调器包括多个室内机,多个室内机与多个实验仓一一对应。
车载抽拉检测实验室10还包括:新风过滤系统,新风过滤系统包括:送风系统和排风系统,送风系统设有新风机和过滤装置,且送风系统用于向实验仓内送风,外界气体从送风系统进入实验仓内时,新风机和过滤装置对气体进行净化处理,净化后的气体进入实验仓,从而保证进入实验仓内的气体清洁度较高。排风系统用于将实验仓内的气体排出车载抽拉检测实验室10。排风系统也可以设置有新风机和过滤装置,排风系统用于将实验仓内的气体经过滤后排出车载抽拉检测实验室10。
送风系统和排风系统均可以设置为多个,每个实验仓与一个送风系统和一个排风系统对应设置,由此使得各个实验仓的空气相互不发生干扰。
车载抽拉检测实验室10具有智能舱压控制系统,新风过滤系统与智能舱压控制系统电连接。智能舱压控制系统可调节送风系统和排风系统,以使各个实验仓内保持特定所需要的压强。
实验仓由空调器调节温度和湿度且由驱动装置5驱动抽拉,支撑架体2内设置有设备间21,空调器的空调室外机、驱动装置5的驱动控制柜和智能舱压控制系统的舱压控制柜设置在设备间21内,由此可以保证实验仓内整洁、无其它辅助设备,同时也使得车载抽拉检测实验室10的结构更加紧凑。
参照图1、图3-图6所示,根据本申请另一方面实施例的车辆100包括:车体20和上述实施例的用于病毒检测的车载抽拉检测实验室10。
具体地,车载抽拉检测实验室10具有置于车体20上的车载状态以及与车体20分离的离车状态。
可选地,支撑架体2与车体20之间通过紧固件实现可拆卸式连接。如图2所示,支撑架体2上设置有固定支臂22,固定支臂22上开设有螺栓孔221,螺栓紧固件适于穿设该螺栓孔221后紧固在车体20上,以实现支撑架体2与车体20的固定,此时,车载抽拉检测实验室10处于车载状态,同时也可以避免车辆100运行时,车载抽拉检测实验室10从车体20上滑落。当需要将支撑架体2与车体20分离时,只需将螺栓紧固件取下,再将撑脚4的横向伸缩脚41伸出支撑架体2,将竖向伸缩脚42沿竖向伸展至撑地状态,便可以将车体20驶离支撑架体2下方,这样,车载抽拉检测实验室10与车体20处于离车状态,车体20可以用于运输其它货物或其它实验室,有利于能源的合理调配。
根据本申请实施例的车辆100,可以运载车载抽拉检测实验室10到指定地点,从而满 足疫情地区的使用需求。
在本说明书的描述中,参考术语“一个实施例”、“一些实施例”、“示例”、“具体示例”或“一些示例”等的描述意指结合该实施例或示例描述的具体特征、结构、材料或者特点包含于本申请的至少一个实施例或示例中。在本说明书中,对上述术语的示意性表述不必须针对的是相同的实施例或示例。而且,描述的具体特征、结构、材料或者特点可以在任何的一个或多个实施例或示例中以合适的方式结合。此外,本领域的技术人员可以将本说明书中描述的不同实施例或示例进行接合和组合。
尽管上面已经示出和描述了本申请的实施例,可以理解的是,上述实施例是示例性的,不能理解为对本申请的限制,本领域的普通技术人员在本申请的范围内可以对上述实施例进行变化、修改、替换和变型。

Claims (18)

  1. 一种用于病毒检测的车载抽拉检测实验室,其特征在于,包括:
    设备仓(1);
    支撑架体(2),所述设备仓(1)设置于所述支撑架体(2)内,所述支撑架体(2)具有多个撑脚(4),所述撑脚(4)具有离地状态和撑地状态;
    多个实验仓,多个所述实验仓可抽拉地连接于所述支撑架体(2)。
  2. 根据权利要求1所述的用于病毒检测的车载抽拉检测实验室,其特征在于,所述撑脚(4)适于沿横向和纵向伸缩。
  3. 根据权利要求2所述的用于病毒检测的车载抽拉检测实验室,其特征在于,所述撑脚(4)包括:横向伸缩脚(41)和竖向伸缩脚(42),所述横向伸缩脚(41)适于横向伸出所述支撑架体(2)或横向缩回所述支撑架体(2)内,所述竖向伸缩脚(42)设置在所述横向伸缩脚(41)上,且所述竖向伸缩脚(42)适于沿竖向伸缩,以使所述撑脚(4)处于所述离地状态或所述撑地状态。
  4. 根据权利要求1所述的用于病毒检测的车载抽拉检测实验室,其特征在于,所述支撑架体(2)内设置有驱动装置(5),所述驱动装置(5)适于驱动所述实验仓至少部分地抽出所述支撑架体(2)或者缩回所述支撑架体(2)。
  5. 根据权利要求4所述的用于病毒检测的车载抽拉检测实验室,其特征在于,所述驱动装置(5)包括:驱动缸(51)和驱动杆(52),所述驱动缸(51)适于驱动所述驱动杆(52)往复移动,所述驱动杆(52)与所述实验仓相连接。
  6. 根据权利要求5所述的用于病毒检测的车载抽拉检测实验室,其特征在于,所述驱动杆(52)为多个,每个所述实验仓由对应的所述驱动杆(52)驱动。
  7. 根据权利要求1所述的用于病毒检测的车载抽拉检测实验室,其特征在于,多个所述实验仓包括:位于所述设备仓(1)第一侧的第一实验仓(31)以及位于所述设备仓(1)第二侧的第二实验仓(32),所述第一实验仓(31)和所述第二实验仓(32)均沿所述设备仓(1)的长度方向设置。
  8. 根据权利要求7所述的用于病毒检测的车载抽拉检测实验室,其特征在于,所述第一实验仓(31)包括:第一样本接收制备区(311)以及扩增区(312),所述第二实验仓(32)包括:试剂准备区(321)以及第二样本接收制备区(322),所述试剂准备区(321)与所述第一样本接收制备区(311)之间设置有第一传递窗(61),所述第一样本接收制备区(311)与所述第二样本接收制备区(322)之间设置有第二传递窗(62),所述第二样本接收制备区(322)与所述扩增区(312)之间设置有第三传递窗(63)。
  9. 根据权利要求8所述的用于病毒检测的车载抽拉检测实验室,其特征在于,所述设备仓(1)包括中间分隔壁(11),所述中间分隔壁(11)的第一侧空间与所述第一实验仓(31)连通,所述中间分隔壁(11)的第二侧空间与所述第二实验仓(32)连通,所述第一传递窗(61)、所述第二传递窗(62)、所述第三传递窗(63)均设置在所述中间分隔壁(11)上。
  10. 根据权利要求8所述的用于病毒检测的车载抽拉检测实验室,其特征在于,所述试剂准备区(321)为正压环境,所述第一样本接收制备区(311)、所述扩增区(312)、所述第二样本接收制备区(322)均为负压环境,且所述扩增区(312)的负压最强。
  11. 根据权利要求1或8所述的用于病毒检测的车载抽拉检测实验室,其特征在于,所述支撑架体(2)内设置有多个缓冲间,每个所述缓冲间具有与外界可选择性连通的外门(71)以及与对应的所述实验仓可选择性连通的内门(72)。
  12. 根据权利要求1所述的用于病毒检测的车载抽拉检测实验室,其特征在于,还包括:空调器,所述空调器用于调节每个所述实验仓的温度和湿度,所述空调器包括多个室内机,多个所述室内机与多个所述实验仓一一对应。
  13. 根据权利要求1所述的用于病毒检测的车载抽拉检测实验室,其特征在于,还包括:新风过滤系统,所述新风过滤系统包括:送风系统和排风系统,所述送风系统设有新风机且用于向所述实验仓内送风,所述排风系统用于将所述实验仓内的气体排出所述车载抽拉检测实验室。
  14. 根据权利要求13所述的用于病毒检测的车载抽拉检测实验室,其特征在于,所述车载抽拉检测实验室具有智能舱压控制系统,所述新风过滤系统与所述智能舱压控制系统电连接。
  15. 根据权利要求14所述的用于病毒检测的车载抽拉检测实验室,其特征在于,所述实验仓由空调器调节温度和湿度且由驱动装置(5)驱动抽拉,所述支撑架体(2)内设置有设备间(21),所述空调器的空调室外机、所述驱动装置(5)的驱动控制柜和所述智能舱压控制系统的舱压控制柜设置在所述设备间(21)内。
  16. 一种车辆,其特征在于,包括:车体(20)和权利要求1-15中任一项所述的用于病毒检测的车载抽拉检测实验室。
  17. 根据权利要求16所述的车辆,其特征在于,所述车载抽拉检测实验室具有置于所述车体(20)上的车载状态以及与所述车体(20)分离的离车状态。
  18. 根据权利要求17所述的车辆,其特征在于,所述支撑架体(2)与所述车体(20)之间通过紧固件实现可拆卸式连接。
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