WO2022036050A1 - Systèmes et procédés pour sondes endovasculaires souples à l'échelle micrométrique pour l'enregistrement neuronal - Google Patents

Systèmes et procédés pour sondes endovasculaires souples à l'échelle micrométrique pour l'enregistrement neuronal Download PDF

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Publication number
WO2022036050A1
WO2022036050A1 PCT/US2021/045679 US2021045679W WO2022036050A1 WO 2022036050 A1 WO2022036050 A1 WO 2022036050A1 US 2021045679 W US2021045679 W US 2021045679W WO 2022036050 A1 WO2022036050 A1 WO 2022036050A1
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WO
WIPO (PCT)
Prior art keywords
less
component
micrometers
electrical
equal
Prior art date
Application number
PCT/US2021/045679
Other languages
English (en)
Inventor
Anqi Zhang
Charles M. Lieber
Emiri T. MANDEVILLE
Eng H. Lo
Original Assignee
President And Fellows Of Harvard College
The General Hospital Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by President And Fellows Of Harvard College, The General Hospital Corporation filed Critical President And Fellows Of Harvard College
Publication of WO2022036050A1 publication Critical patent/WO2022036050A1/fr

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/25Bioelectric electrodes therefor
    • A61B5/279Bioelectric electrodes therefor specially adapted for particular uses
    • A61B5/291Bioelectric electrodes therefor specially adapted for particular uses for electroencephalography [EEG]
    • A61B5/293Invasive
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6867Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive specially adapted to be attached or implanted in a specific body part
    • A61B5/6876Blood vessel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/05Electrodes for implantation or insertion into the body, e.g. heart electrode

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

La présente divulgation concerne de manière générale une électronique injectable qui peut être insérée dans un sujet, par exemple, dans un vaisseau sanguin. Certains modes de réalisation comprennent un dispositif comprenant des éléments électriques qui sont injectés dans un sujet, par exemple pour permettre la détection de neurones et/ou stimuler une réponse. Dans certains cas, le dispositif peut être encapsulé partiellement par un cathéter, pour être inséré dans un sujet. Dans certains cas, les éléments électriques peuvent être en communication électrique avec une carte de circuit imprimé externe par l'intermédiaire de contacts électriques sur le dispositif par l'intermédiaire d'un composant de jonction. Dans un ensemble de modes de réalisation, le composant de jonction comprend un fil-guide qui confère des propriétés appropriées (par exemple, une raideur mécanique d'au moins 30 nN m) à une partie du dispositif, par exemple, pour permettre l'insertion du dispositif dans un vaisseau sanguin. Certains modes de réalisation concernent également des systèmes et des procédés de fabrication et d'utilisation dudit dispositif.
PCT/US2021/045679 2020-08-14 2021-08-12 Systèmes et procédés pour sondes endovasculaires souples à l'échelle micrométrique pour l'enregistrement neuronal WO2022036050A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063066042P 2020-08-14 2020-08-14
US63/066,042 2020-08-14

Publications (1)

Publication Number Publication Date
WO2022036050A1 true WO2022036050A1 (fr) 2022-02-17

Family

ID=80247365

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2021/045679 WO2022036050A1 (fr) 2020-08-14 2021-08-12 Systèmes et procédés pour sondes endovasculaires souples à l'échelle micrométrique pour l'enregistrement neuronal

Country Status (1)

Country Link
WO (1) WO2022036050A1 (fr)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070255379A1 (en) * 2003-06-04 2007-11-01 Williams Michael S Intravascular device for neuromodulation
US20080015459A1 (en) * 2002-08-21 2008-01-17 New York University Brain- machine interface systems and methods
US20130206454A1 (en) * 2010-08-26 2013-08-15 Acandis Gmbh & Co. Kg Electrode for medical applications, system having such an electrode, and method for producing such an electrode
US20160287325A1 (en) * 2011-11-07 2016-10-06 Medtronic Ardian Luxembourg S.A.R.L. Endovascular Nerve Monitoring Devices and Associated Systems and Methods
US20190046119A1 (en) * 2011-10-04 2019-02-14 Thomas James Oxley Methods for sensing or stimulating activity of tissue
US20200008924A9 (en) * 2015-10-20 2020-01-09 Nicholas Lachlan OPIE Endovascular device for sensing and or stimulating tissue

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080015459A1 (en) * 2002-08-21 2008-01-17 New York University Brain- machine interface systems and methods
US20070255379A1 (en) * 2003-06-04 2007-11-01 Williams Michael S Intravascular device for neuromodulation
US20130206454A1 (en) * 2010-08-26 2013-08-15 Acandis Gmbh & Co. Kg Electrode for medical applications, system having such an electrode, and method for producing such an electrode
US20190046119A1 (en) * 2011-10-04 2019-02-14 Thomas James Oxley Methods for sensing or stimulating activity of tissue
US20160287325A1 (en) * 2011-11-07 2016-10-06 Medtronic Ardian Luxembourg S.A.R.L. Endovascular Nerve Monitoring Devices and Associated Systems and Methods
US20200008924A9 (en) * 2015-10-20 2020-01-09 Nicholas Lachlan OPIE Endovascular device for sensing and or stimulating tissue

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