WO2022016398A1 - Enteric-coated vacant capsules from hypromellose - Google Patents

Enteric-coated vacant capsules from hypromellose Download PDF

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Publication number
WO2022016398A1
WO2022016398A1 PCT/CN2020/103381 CN2020103381W WO2022016398A1 WO 2022016398 A1 WO2022016398 A1 WO 2022016398A1 CN 2020103381 W CN2020103381 W CN 2020103381W WO 2022016398 A1 WO2022016398 A1 WO 2022016398A1
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WO
WIPO (PCT)
Prior art keywords
capsule
capsule body
groove
annular
enteric
Prior art date
Application number
PCT/CN2020/103381
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French (fr)
Chinese (zh)
Inventor
俞愈
俞栋
俞三愈
俞学文
王孟军
Original Assignee
绍兴康可胶囊有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 绍兴康可胶囊有限公司 filed Critical 绍兴康可胶囊有限公司
Priority to PCT/CN2020/103381 priority Critical patent/WO2022016398A1/en
Publication of WO2022016398A1 publication Critical patent/WO2022016398A1/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816Wall or shell material

Abstract

Enteric-coated vacant capsules from hypromellose, comprising a first capsule body and a second capsule body. A first annular plate is installed on an upper side of the first capsule, a first groove is provided inside of the first annular plate, a second annular plate is installed on an upper side of the first annular plate, and an annular notch is provided inside of the second capsule body. By providing a second groove within the first groove, a limiting block can be clamped within the second groove, thereby enabling the first capsule body and the second capsule body to be tightly closed; in addition, the provided annular notch enables the annular notch to cooperate with an annular protrusion, which can further seal the device, thus reducing the dampness of the capsule due to long-term storage, thereby ensuring the efficacy of the capsule.

Description

肠溶羟丙甲纤维素空心胶囊Enteric-coated hypromellose hollow capsules 技术领域technical field
本发明属于胶囊技术领域,特别是涉及一种肠溶羟丙甲纤维素空心胶囊。The invention belongs to the technical field of capsules, in particular to an enteric-coated hypromellose hollow capsule.
背景技术Background technique
肠溶羟丙甲纤维素空心胶囊由药用明胶加辅料精制而成的帽、体两节胶囊壳组成。主要用于盛装固体及液体药物。如自制散剂、保健品、药剂等,为服用者解决了难入口、口感差的问题,真正实现了良药不再苦口。Enteric-coated hypromellose hollow capsules are composed of cap and body two-section capsule shells refined from medicinal gelatin and auxiliary materials. Mainly used to hold solid and liquid medicines. For example, self-made powders, health products, pharmaceuticals, etc., solve the problems of difficult entrance and poor taste for users, and truly realize that good medicine is no longer bitter.
技术问题technical problem
传统胶囊安装比较单一,密封性不好,在长时间放置时,容易受潮,从而导致药效降低。The traditional capsules are relatively simple in installation and have poor sealing performance. When they are placed for a long time, they are easily damped, resulting in a decrease in the efficacy of the medicine.
技术解决方案technical solutions
本发明的目的在于提供一种肠溶羟丙甲纤维素空心胶囊,通过在第一凹槽内开设的第二凹槽,可以将限位块卡接在第二凹槽内,从而使第一囊体和第二囊体紧密闭合,而设置的环形凹口,使环形凹口与环形凸块配合,可以对装置进一步密封,减少了胶囊因长时间放置出现受潮的现象,从而保证了胶囊的药效,解决了现有的技术问题。The purpose of the present invention is to provide an enteric-coated hypromellose hollow capsule, through the second groove opened in the first groove, the limit block can be clamped in the second groove, thereby making the first groove The capsule body and the second capsule body are tightly closed, and the annular notch is arranged so that the annular notch cooperates with the annular projection, which can further seal the device, reduce the phenomenon of the capsule being damp due to long-term placement, thus ensuring the capsule's performance. The medicinal effect solves the existing technical problems.
为解决上述技术问题,本发明是通过以下技术方案实现的:In order to solve the above-mentioned technical problems, the present invention is achieved through the following technical solutions:
一种肠溶羟丙甲纤维素空心胶囊,包括第一囊体、第二囊体,第一囊体的上侧安装有第一环形板,第一环形板的内部开设有第一凹槽,第一环形板的上侧安装有第二环形板;第二囊体的内部开设有环形凹口,第二环形板的周侧安装有环形凸块,且环形凸块配合在环形凹口内,第二囊体的底部均布安装有多个限位柱,限位柱的一侧安装有限位块,第一凹槽的内部开设有第二凹槽,且限位块配合在第二凹槽内。An enteric-coated hypromellose hollow capsule, comprising a first capsule body and a second capsule body, a first annular plate is installed on the upper side of the first capsule body, and a first groove is opened inside the first annular plate, A second annular plate is installed on the upper side of the first annular plate; an annular recess is provided inside the second bag body, an annular projection is installed on the peripheral side of the second annular plate, and the annular projection is fitted in the annular recess, the The bottoms of the two capsules are evenly installed with a plurality of limit posts, a limit block is installed on one side of the limit post, a second groove is opened inside the first groove, and the limit block fits in the second groove .
可选的,第一囊体和第二囊体内部设置有有可食用保护膜。Optionally, an edible protective film is provided inside the first capsule body and the second capsule body.
可选的,第二环形板与第二囊体滑动配合。Optionally, the second annular plate is slidably fitted with the second bladder.
可选的,限位柱与第一凹槽滑动配合。Optionally, the limit post is slidably matched with the first groove.
可选的,第一囊体和第二囊体的外表面设置若干凸起。Optionally, several protrusions are provided on the outer surfaces of the first capsule body and the second capsule body.
可选的,第一囊体和第二囊体的直径相同。Optionally, the diameters of the first capsule body and the second capsule body are the same.
有益效果beneficial effect
本发明的一个实施例通过在第一凹槽内开设的第二凹槽,可以将限位块卡接在第二凹槽内,从而使第一囊体和第二囊体紧密闭合,而设置的环形凹口,使环形凹口与环形凸块配合,可以对装置进一步密封,减少了胶囊因长时间放置出现受潮的现象,从而保证了胶囊的药效。In one embodiment of the present invention, through the second groove opened in the first groove, the limit block can be clamped in the second groove, so that the first bag body and the second bag body are tightly closed, and the set The annular notch is matched with the annular projection, which can further seal the device, reduce the phenomenon of the capsule being damp due to long-term placement, thereby ensuring the efficacy of the capsule.
当然,实施本发明的任一产品并不一定需要同时达到以上所述的所有优点。Of course, it is not necessary for any product embodying the present invention to achieve all of the above-described advantages simultaneously.
附图说明Description of drawings
图1为本发明一实施例的立体结构示意图;FIG. 1 is a schematic three-dimensional structure diagram of an embodiment of the present invention;
图2为本发明一实施例的限位柱示意图;2 is a schematic diagram of a limit post according to an embodiment of the present invention;
图3为本发明一实施例的第二环形板示意图;3 is a schematic diagram of a second annular plate according to an embodiment of the present invention;
图4为本发明一实施例的剖面图;4 is a cross-sectional view of an embodiment of the present invention;
图5为本发明一实施例的第一环形板示意图;5 is a schematic diagram of a first annular plate according to an embodiment of the present invention;
图6为图4中A处的放大图。FIG. 6 is an enlarged view of A in FIG. 4 .
本发明的最佳实施方式BEST MODE FOR CARRYING OUT THE INVENTION
下面将结合本发明实施例中的附图,对本发明实施例中的技术方案进行清楚、完整地描述,显然,所描述的实施例仅仅是本发明一部分实施例,而不是全部的实施例。基于本发明中的实施例,本领域普通技术人员在没有作出创造性劳动前提下所获得的所有其它实施例,都属于本发明保护的范围。The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.
为了保持本发明实施例的以下说明清楚且简明,本发明省略了已知功能和已知部件的详细说明。In order to keep the following description of the embodiments of the present invention clear and concise, the present invention omits detailed descriptions of well-known functions and well-known components.
请参阅图1-6所示,在本实施例中提供了一种肠溶羟丙甲纤维素空心胶囊,包括第一囊体1、第二囊体2,第一囊体1的上侧安装有第一环形板3,第一环形板3的内部开设有第一凹槽7,第一环形板3的上侧安装有第二环形板6;第二囊体2的内部开设有环形凹口11,第二环形板6的周侧安装有环形凸块8,且环形凸块8配合在环形凹口11内,第二囊体2的底部均布安装有多个限位柱4,限位柱4的一侧安装有限位块5,第一凹槽7的内部开设有第二凹槽9,且限位块5配合在第二凹槽9内。Please refer to FIGS. 1-6. In this embodiment, an enteric-coated hypromellose hollow capsule is provided, including a first capsule body 1 and a second capsule body 2, and the upper side of the first capsule body 1 is installed There is a first annular plate 3, a first groove 7 is opened inside the first annular plate 3, a second annular plate 6 is installed on the upper side of the first annular plate 3; an annular notch is opened inside the second bag 2 11. An annular bump 8 is installed on the peripheral side of the second annular plate 6, and the annular bump 8 is fitted in the annular recess 11. A plurality of limit posts 4 are evenly installed on the bottom of the second bag body 2. A limit block 5 is installed on one side of the column 4 , a second groove 9 is opened inside the first groove 7 , and the limit block 5 fits in the second groove 9 .
本实施例一个方面的应用为:在需要安装胶囊时,捏住第二囊体2向第二环形板6移动,环形凸块8滑动至环形凹口11内,限位柱4滑至第一凹槽7内,带动限位块5卡入第二凹槽9内,从而可以将第一囊体1和第二囊体2闭合。One aspect of the application of this embodiment is: when the capsule needs to be installed, pinch the second capsule body 2 and move it toward the second annular plate 6 , the annular projection 8 slides into the annular recess 11 , and the limit post 4 slides to the first In the groove 7, the limiting block 5 is driven to be clamped into the second groove 9, so that the first capsule body 1 and the second capsule body 2 can be closed.
通过在第一凹槽7内开设的第二凹槽9,可以将限位块5卡接在第二凹槽9内,从而使第一囊体1和第二囊体2紧密闭合,而设置的环形凹口11,使环形凹口11与环形凸块8配合,可以对装置进一步密封,减少了胶囊因长时间放置出现受潮的现象,从而保证了胶囊的药效。Through the second groove 9 opened in the first groove 7, the limit block 5 can be clamped in the second groove 9, so that the first capsule body 1 and the second capsule body 2 are tightly closed, and the The annular notch 11 is matched with the annular convex block 8, which can further seal the device, reduce the phenomenon of the capsule being damp due to long-term placement, thereby ensuring the efficacy of the capsule.
在本实施例的一个方面中,第一囊体1和第二囊体2内部设置有有可食用保护膜10,第二环形板6与第二囊体2滑动配合。In one aspect of this embodiment, an edible protective film 10 is provided inside the first capsule body 1 and the second capsule body 2 , and the second annular plate 6 is slidably fitted with the second capsule body 2 .
在本实施例的一个方面中,限位柱4与第一凹槽7滑动配合,第一囊体1和第二囊体2的直径相同。In an aspect of this embodiment, the limiting post 4 is in sliding fit with the first groove 7, and the diameters of the first capsule body 1 and the second capsule body 2 are the same.
在本实施例的一个方面中,第一囊体1和第二囊体2的外表面设置若干凸起,通过设置的若干凸起,增大手与胶囊的摩擦力,防止胶囊掉落。In an aspect of this embodiment, the outer surfaces of the first capsule body 1 and the second capsule body 2 are provided with several protrusions, and the friction between the hand and the capsule is increased by the provided several protrusions, so as to prevent the capsule from falling.
上述实施例可以相互结合。The above-described embodiments may be combined with each other.
需要注意的是,在本说明书的描述中,诸如“第一”、“第二”等的描述仅仅是用于区分各特征,并没有实际的次序或指向意义,本申请并不以此为限。It should be noted that in the description of this specification, descriptions such as "first", "second", etc. are only used to distinguish various features, and have no actual order or directional meaning, and the application is not limited by this .
在本说明书的描述中,参考术语“一个实施例”、“示例”、“具体示例”等的描述意指结合该实施例或示例描述的具体特征、结构、材料或者特点包含于本发明的至少一个实施例或示例中。在本说明书中,对上述术语的示意性表述不一定指的是相同的实施例或示例。而且,描述的具体特征、结构、材料或者特点可以在任何的一个或多个实施例或示例中以合适的方式结合。In the description of this specification, description with reference to the terms "one embodiment," "example," "specific example," etc. means that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one aspect of the present invention. in one embodiment or example. In this specification, schematic representations of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
以上公开的本发明优选实施例只是用于帮助阐述本发明。优选实施例并没有详尽叙述所有的细节,也不限制该发明仅为所述的具体实施方式。显然,根据本说明书的内容,可作很多的修改和变化。本说明书选取并具体描述这些实施例,是为了更好地解释本发明的原理和实际应用,从而使所属技术领域技术人员能很好地理解和利用本发明。本发明仅受权利要求书及其全部范围和等效物的限制。The above-disclosed preferred embodiments of the present invention are provided only to help illustrate the present invention. The preferred embodiments do not exhaust all the details, nor do they limit the invention to only the described embodiments. Obviously, many modifications and variations are possible in light of the content of this specification. These embodiments are selected and described in this specification in order to better explain the principles and practical applications of the present invention, so that those skilled in the art can well understand and utilize the present invention. The present invention is to be limited only by the claims and their full scope and equivalents.

Claims (6)

  1. 一种肠溶羟丙甲纤维素空心胶囊,其特征在于,包括:第一囊体(1)、第二囊体(2),第一囊体(1)的上侧安装有第一环形板(3),第一环形板(3)的内部开设有第一凹槽(7),第一环形板(3)的上侧安装有第二环形板(6);An enteric-coated hypromellose hollow capsule, characterized in that it comprises: a first capsule body (1), a second capsule body (2), and a first annular plate is installed on the upper side of the first capsule body (1) (3), a first groove (7) is opened inside the first annular plate (3), and a second annular plate (6) is installed on the upper side of the first annular plate (3);
    第二囊体(2)的内部开设有环形凹口(11),第二环形板(6)的周侧安装有环形凸块(8),且环形凸块(8)配合在环形凹口(11)内,第二囊体(2)的底部均布安装有多个限位柱(4),限位柱(4)的一侧安装有限位块(5),第一凹槽(7)的内部开设有第二凹槽(9),且限位块(5)配合在第二凹槽(9)内。An annular recess (11) is opened inside the second bag body (2), an annular projection (8) is installed on the peripheral side of the second annular plate (6), and the annular projection (8) fits in the annular recess ( In 11), a plurality of limit posts (4) are evenly installed on the bottom of the second capsule (2), a limit block (5) is installed on one side of the limit post (4), and the first groove (7) A second groove (9) is opened in the inner part of the casing, and the limiting block (5) is matched in the second groove (9).
  2. 如权利要求1所述的一种肠溶羟丙甲纤维素空心胶囊,其特征在于,第一囊体(1)和第二囊体(2)内部设置有有可食用保护膜(10)。The enteric-coated hypromellose hollow capsule according to claim 1, wherein an edible protective film (10) is provided inside the first capsule body (1) and the second capsule body (2).
  3. 如权利要求1所述的一种肠溶羟丙甲纤维素空心胶囊,其特征在于,第二环形板(6)与第二囊体(2)滑动配合。The enteric-coated hypromellose hollow capsule according to claim 1, characterized in that the second annular plate (6) is slidingly matched with the second capsule body (2).
  4. 如权利要求1所述的一种肠溶羟丙甲纤维素空心胶囊,其特征在于,限位柱(4)与第一凹槽(7)滑动配合。The enteric-coated hypromellose hollow capsule according to claim 1, characterized in that the limit post (4) is slidingly matched with the first groove (7).
  5. 如权利要求1所述的一种肠溶羟丙甲纤维素空心胶囊,其特征在于,第一囊体(1)和第二囊体(2)的外表面设置若干凸起。The enteric-coated hypromellose hollow capsule according to claim 1, characterized in that a plurality of protrusions are arranged on the outer surfaces of the first capsule body (1) and the second capsule body (2).
  6. 如权利要求1所述的一种肠溶羟丙甲纤维素空心胶囊,其特征在于,第一囊体(1)和第二囊体(2)的直径相同。The enteric-coated hypromellose hollow capsule according to claim 1, wherein the diameter of the first capsule body (1) and the second capsule body (2) are the same.
      
PCT/CN2020/103381 2020-07-22 2020-07-22 Enteric-coated vacant capsules from hypromellose WO2022016398A1 (en)

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CN202080006147.5A CN113164404B (en) 2020-07-22 2020-07-22 Enteric hydroxypropyl methylcellulose hollow capsule
PCT/CN2020/103381 WO2022016398A1 (en) 2020-07-22 2020-07-22 Enteric-coated vacant capsules from hypromellose

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US4792451A (en) * 1986-12-20 1988-12-20 Su-Heung Capsule Co., Ltd. Medicinal capsule
IE58468B1 (en) * 1984-10-25 1993-09-22 Warner Lambert Co Method for sealing capsules and capsule
CN1146416A (en) * 1995-09-23 1997-04-02 梁周焕 Bag for medicine or food
CN1321085A (en) * 1998-09-28 2001-11-07 沃纳-兰伯特公司 Enteric and colonic delivery using HPMC capsules
CN204352220U (en) * 2014-11-25 2015-05-27 浙江宏辉胶丸有限公司 A kind of capsule being provided with reinforcement button
CN206587195U (en) * 2016-11-29 2017-10-27 新昌县渲渲工业产品设计有限公司 A kind of capsule for preventing that medicine from leaking
CN208448178U (en) * 2017-10-10 2019-02-01 新昌县凯泰胶丸有限公司 A kind of capsule structure for preventing drug from leaking
CN110115685A (en) * 2019-06-19 2019-08-13 江苏力凡胶囊有限公司 A kind of empty hard capsule of the filling liquid with closing component structure
CN211050315U (en) * 2019-08-13 2020-07-21 浙江华光胶囊股份有限公司 Hollow capsule suitable for traditional Chinese medicine capsule preparation
CN211050267U (en) * 2019-08-15 2020-07-21 新昌县联通胶囊有限公司 Plant hollow capsule

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CN106265587A (en) * 2016-08-25 2017-01-04 江苏力凡胶囊有限公司 Enteric hollow capsule and preparation method thereof

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Publication number Priority date Publication date Assignee Title
IE58468B1 (en) * 1984-10-25 1993-09-22 Warner Lambert Co Method for sealing capsules and capsule
US4792451A (en) * 1986-12-20 1988-12-20 Su-Heung Capsule Co., Ltd. Medicinal capsule
CN1146416A (en) * 1995-09-23 1997-04-02 梁周焕 Bag for medicine or food
CN1321085A (en) * 1998-09-28 2001-11-07 沃纳-兰伯特公司 Enteric and colonic delivery using HPMC capsules
CN204352220U (en) * 2014-11-25 2015-05-27 浙江宏辉胶丸有限公司 A kind of capsule being provided with reinforcement button
CN206587195U (en) * 2016-11-29 2017-10-27 新昌县渲渲工业产品设计有限公司 A kind of capsule for preventing that medicine from leaking
CN208448178U (en) * 2017-10-10 2019-02-01 新昌县凯泰胶丸有限公司 A kind of capsule structure for preventing drug from leaking
CN110115685A (en) * 2019-06-19 2019-08-13 江苏力凡胶囊有限公司 A kind of empty hard capsule of the filling liquid with closing component structure
CN211050315U (en) * 2019-08-13 2020-07-21 浙江华光胶囊股份有限公司 Hollow capsule suitable for traditional Chinese medicine capsule preparation
CN211050267U (en) * 2019-08-15 2020-07-21 新昌县联通胶囊有限公司 Plant hollow capsule

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