WO2022006866A1 - 头戴式超声神经刺激装置及系统 - Google Patents

头戴式超声神经刺激装置及系统 Download PDF

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Publication number
WO2022006866A1
WO2022006866A1 PCT/CN2020/101387 CN2020101387W WO2022006866A1 WO 2022006866 A1 WO2022006866 A1 WO 2022006866A1 CN 2020101387 W CN2020101387 W CN 2020101387W WO 2022006866 A1 WO2022006866 A1 WO 2022006866A1
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WIPO (PCT)
Prior art keywords
head
ultrasonic
nerve stimulation
ultrasonic transducer
stimulation device
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PCT/CN2020/101387
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English (en)
French (fr)
Inventor
郑海荣
牛丽丽
钟永盛
孟龙
邹俊杰
黄小伟
易沙沙
Original Assignee
深圳先进技术研究院
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Priority to PCT/CN2020/101387 priority Critical patent/WO2022006866A1/zh
Publication of WO2022006866A1 publication Critical patent/WO2022006866A1/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy

Definitions

  • the application belongs to the technical field of medical equipment, and in particular relates to a head-mounted ultrasonic nerve stimulation device and system.
  • Physical brain stimulation neuromodulation technology provides an effective clinical treatment method for patients with brain function diseases.
  • Medical ultrasound is a non-invasive diagnosis and treatment technology that can form a focal point in the human body that is an oblong shape. This feature also enables him to obtain good spatial accuracy and target specific areas of tissue. Medical ultrasound can be divided into high-intensity focused ultrasound and low-intensity focused ultrasound. High-intensity focused ultrasound is a treatment method that directly damages the lesion, while low-intensity focused ultrasound also plays an important role in the field of neuromodulation.
  • the examiner needs to hold the ultrasonic transducer, which is a waste of manpower and inconvenient to operate, and the examinee needs to lie on the bed more often, unable to move freely and it is difficult to match the operation of the ultrasonic transducer. position, which can easily lead to large operating errors.
  • the embodiments of the present application provide a head-mounted ultrasonic nerve stimulation device and system to at least solve the problems that the current ultrasonic transducer is inconvenient to operate and difficult to match with the examinee, which easily leads to operation errors.
  • a head-mounted ultrasonic nerve stimulation device including: a head-mounted support; an ultrasonic transducer for outputting ultrasonic nerve stimulation signals; a connection structure for connecting the head-mounted support and the The ultrasonic transducer is used to adjust the relative position between the head-mounted bracket and the ultrasonic transducer.
  • a head-mounted ultrasonic nerve stimulation system comprising: the above-mentioned head-mounted ultrasonic nerve stimulation device; a display; wherein, the head-mounted ultrasonic nerve stimulation device
  • the ultrasonic transducer is used for acquiring neural image information; the display is used for displaying the neural image information.
  • the wearer can wear the head-worn bracket like a hat to receive the nerve stimulation operation, the wearer can move freely to obtain a better ultrasonic medical experience, and the head-worn bracket and The ultrasonic transducers are connected through a connection structure, and the relative position between the head-mounted bracket and the ultrasonic transducer can be adjusted through the connection structure, so that the ultrasonic transducer has a large operating position range and can reduce operating errors.
  • FIG. 1 shows a schematic structural diagram of an example of a head-mounted ultrasonic nerve stimulation device according to an embodiment of the present application
  • FIG. 2 shows a schematic structural diagram of an example of a head-mounted ultrasonic nerve stimulation device according to an embodiment of the present application
  • FIG. 3A shows a schematic structural diagram of an ultrasonic transducer fixing module in a first state according to an embodiment of the present application
  • FIG. 3B shows a schematic structural diagram of an ultrasonic transducer fixing module in a second state according to an embodiment of the present application
  • FIG. 4 shows a structural block diagram of an example of a head-mounted ultrasonic nerve stimulation system according to an embodiment of the present application.
  • ultrasound technology is used to stimulate human tissue, and several effects are produced to cause changes in diseased tissue, so as to achieve the purpose of treatment.
  • These ultrasonic effects are mainly thermal effects, mechanical effects and cavitation effects.
  • part of the sound energy is absorbed by the medium due to the viscosity and thermal conductivity of the medium during the propagation of the ultrasonic wave, and the result is converted into heat energy and causes the local temperature to rise.
  • certain reactions occur, such as vasodilation, accelerated blood circulation, and increased tissue metabolism, thereby promoting the absorption and dissipation of pathological products.
  • the mechanical effect of particle vibration in the medium causes acceleration, rotation, and rushing vibrations of some fine tissues, thus playing a massage role and enhancing the semi-permeable membrane. It also has a good effect on the material exchange of cells and tissue nutrition.
  • cavitation In the stimulation mechanism of the cavitation effect, during the propagation of ultrasonic waves, when sufficient ultrasonic intensity encounters some liquid tissues in the human body, cavitation will be generated, which can generate high-intensity micro shock waves, which can change or destroy lesions tissue for therapeutic purposes.
  • the head-mounted ultrasonic nerve stimulation device and system disclosed in the embodiments of the present application mainly relate to the structure or connection relationship of each component in the wearable ultrasonic nerve stimulation device or system, and various The stimulatory mechanism of the effect should not be limited here.
  • the term “if” may be contextually interpreted as “when” or “once” or “in response to determining” or “in response to detecting” .
  • the phrases “if it is determined” or “if the [described condition or event] is detected” may be interpreted, depending on the context, to mean “once it is determined” or “in response to the determination” or “once the [described condition or event] is detected. ]” or “in response to detection of the [described condition or event]”.
  • the mobile terminals described in the embodiments of the present application include, but are not limited to, other portable devices such as mobile phones, laptop computers or tablet computers with touch-sensitive surfaces (eg, touch screen displays and/or touch pads).
  • other portable devices such as mobile phones, laptop computers or tablet computers with touch-sensitive surfaces (eg, touch screen displays and/or touch pads).
  • touch-sensitive surfaces eg, touch screen displays and/or touch pads.
  • the above-described devices are not portable communication devices, but rather desktop computers with touch-sensitive surfaces (eg, touch screen displays and/or touch pads).
  • FIG. 1 shows a schematic structural diagram of an example of a head-mounted ultrasonic nerve stimulation device according to an embodiment of the present application.
  • the head-mounted ultrasonic nerve stimulation device 100 includes a head-mounted support 110 , a connecting structure 120 and an ultrasonic transducer 130 .
  • the head-mounted bracket 110 can be worn on the head by the wearer, and it can be various shape structures suitable for wearing on the head, such as a half-ring bracket or a ring-shaped bracket, and the like.
  • the ultrasonic transducer 130 may output an ultrasonic nerve stimulation signal, and the working parameters (eg, power, frequency, waveform, etc.) of the ultrasonic nerve stimulation signal may be preset, and may be a variety of ultrasonic nerve stimulation signals. It should be understood that an ultrasonic transducer (also referred to as an ultrasonic probe) is an important part of medical ultrasonic equipment, which can perform conversion between electrical and mechanical energy.
  • the ultrasonic transducer 130 may integrate an ultrasonic generating function, so that the ultrasonic transducer 130 can independently and autonomously generate a driving signal (electrical signal) and output a corresponding ultrasonic nerve stimulation signal (acoustic signal). ).
  • the ultrasonic transducer 130 may be electrically connected with an ultrasonic generator, and the ultrasonic generator (also referred to as an ultrasonic driving power source), which can convert commercial power into an ultrasonic transducer Matching high-frequency alternating current signals (for example, ultrasonic electrical signals of various parameter types) to drive the ultrasonic transducer to work.
  • the ultrasonic transducer can output a corresponding ultrasonic nerve stimulation signal (acoustic signal) according to the driving signal generated by the ultrasonic generator.
  • connection structure 120 connects the head-mounted bracket 110 and the ultrasonic transducer 130 , and the relative position between the head-mounted bracket 110 and the ultrasonic transducer 130 can be adjusted through the connection structure 120 . It should be understood that, with regard to the adjustment direction of the relative position, it may be limited or diversified (for example, it may be adjusted in a direction at any angle with respect to the head mount bracket 110 ).
  • the wearer when the wearer uses the head-mounted ultrasonic nerve stimulation device, the wearer does not need to lie down, and only needs to put on the head-mounted support like a hat, which is very convenient to operate, and the wearer has relatively Large free space.
  • the relative position between the head-mounted bracket and the ultrasonic transducer can be adjusted through the connection structure, so that the ultrasonic transducer can have more action positions, and the operation error can be reduced.
  • the "wearer” or “user” of the head-mounted ultrasonic nerve stimulation device or system may be various identities, such as a doctor, a patient, and the like. References to the terms “doctor” and “patient” elsewhere in this document are for example only and are not intended to limit the identity of the wearer, for example in some situations a wearer may wear a head-worn ultrasonic nerve stimulation device to Stimulate yourself while the wearer is both a doctor and a patient.
  • FIG. 2 shows a schematic structural diagram of an example of a head-mounted ultrasonic nerve stimulation device according to an embodiment of the present application.
  • the head mount 110 is a retractable head mount. Therefore, the head-mounted bracket can be adapted to the size of the head of different wearers, thereby expanding the application range of the head-mounted ultrasonic nerve stimulation device.
  • some soft materials such as sponge can be added to the inner surface of the head-wearing support 110 (which can be made of metal or carbon material, etc.) to protect the scalp and reduce additional damage.
  • the head mount 110 may include an annular head ring 14 , a head ring intersection 15 , a fixing member 16 (preferably a screw) and an auxiliary support member 17 .
  • the annular head hoop 14 can be divided into a front head hoop part and a rear head hoop part, the front head hoop part and the rear head hoop part are connected by the head hoop intersection 15 and have overlapping areas, and the head hoop can be adjusted by using the head hoop intersection 15. Size, For example, if the area in which the front and rear head hoop parts overlap is larger, the smaller the head hoop is.
  • the fixing member 16 can be used to fasten and fix the head ring, so that the head ring can be adapted to different head sizes.
  • the head mount 110 is similar to a hat, can be worn on the head, and can be appropriately adjusted according to the size of the head, so as to fit perfectly with the wearer's head.
  • the ultrasonic transducer can be integrated with the wearer, and the wearer's freedom of movement is not restricted during the ultrasonic stimulation of nerves (eg, peripheral nerves).
  • a preset number of auxiliary supports for contacting the head of the wearer of the head-mounted support are provided on the inner circle of the head-mounted support. Therefore, the head-mounted ultrasonic nerve stimulation device can also be supported and fixed assisted by the auxiliary support, so that the head-mounted ultrasonic nerve stimulation device can be reliably and stably fixed on the head of the wearer (for example, a patient) of the head-mounted bracket Department.
  • the head ring is assisted by an auxiliary support 17 to complete the fixing operation of the head ring.
  • the auxiliary support 17 may be an elastic band, which assists in carrying part of the weight of the entire device and buffers the head ring to the head. oppression.
  • the head-worn ultrasonic nerve stimulation device may include an electrode array disposed in a preset number of auxiliary supports, and through which the physiological feedback of a wearer (eg, a patient) of the head-worn support may be collected Signal. Therefore, compared with the current need for doctors to stick multiple electrode devices (or electrode pads) on the patient's head in sequence, in the embodiment of the present application, only the user needs to wear a head frame, which simplifies the operation of the head-mounted ultrasonic nerve.
  • the acquisition process of the stimulation effect data of the stimulation device.
  • the auxiliary support member can be made of elastic materials such as rubber, so that the auxiliary support member has elasticity, and can help to carry a part of the weight of the entire device, so as to buffer the compression of the head by the head-mounted bracket.
  • an electrode device can be installed on (eg, each) auxiliary support 17 . Since the auxiliary support is elastic, the auxiliary support can be in close contact with the head, and the electrode device can effectively sense the signals of brain waves. , in order to capture the changes of various feedback signals (eg, brain wave signals) by the electrode device, which is convenient for analyzing the effect of neural stimulation.
  • various feedback signals eg, brain wave signals
  • the types of physiological feedback signals and the arrangement of electrode devices in the electrode device array should not be limited here, and may be determined according to stimulation effect data.
  • changes in various feedback signals eg, brain wave signals
  • the nerve stimulation effect can be analyzed according to the changes in the feedback signals. Therefore, the electrode device is placed on the fixing bar to avoid additional manual sticking of the electrode device on the head, which can reduce human error.
  • connection structure is a connection structure with a fixed length between the head-mounted bracket and the ultrasonic transducer.
  • the connection structure is a retractable connection structure, whereby the relative position between the head-mounted bracket and the ultrasonic transducer can be adjusted along the direction of the connection structure.
  • the connecting structure includes a connecting rod, and a first connecting piece and a second connecting piece disposed on the connecting rod.
  • the position of the headgear bracket relative to the connecting rod can be adjusted through the first connecting member, and the position of the ultrasonic transducer relative to the connecting rod can be adjusted through the second connecting member. Therefore, the relative position between the head-mounted bracket and the ultrasonic transducer can be adjusted by adjusting the connecting piece on the connecting rod, so that the ultrasonic transducer has a larger operating position range.
  • the connecting rod may include a fixing rod 2 , a supporting rod 3 and a fixing member 4 (preferably a screw), so that the connecting rod has a telescopic function.
  • the fixing rod 2 can be a tubular hollow structure, and the fixing rod 2 is sleeved on the outside of the supporting rod 3, so that the supporting rod 3 can slide up and down or extend and retract in the fixing rod 2, and can pass through the fixing member 4 through the fixed rod 2.
  • a hole (not shown) is used to press and fix the support rod 3, so as to adjust the relative position between the head ring and the ultrasonic transducer along the direction of the connecting rod.
  • the support rod 3 can also be rotated within a range of 360 degrees.
  • both the fixing rod 2 and the supporting rod 3 can be made of materials such as metal or carbon fiber.
  • the first connector includes a clamp for clamping the headgear support.
  • a clamp for clamping the headgear support.
  • the first connecting piece may include a fixing clip 1
  • the fixing clip 1 can fix (or clamp) the head ring, and at the same time the fixing clip 1 can move (for example, slide) the position on the head ring according to actual needs , to clamp different positions of the head-mounted bracket 110 .
  • the fixing clip 1 can be made of materials such as metal or carbon fiber.
  • the second connecting member may include an ultrasonic transducer fixing module for telescopically adjusting the position of the ultrasonic transducer.
  • an ultrasonic transducer fixing module for telescopically adjusting the position of the ultrasonic transducer.
  • a ball shaft module may be provided in the second connecting member for fixing the ultrasonic transducer fixing module, so that the ultrasonic transducer fixing module can be driven by the ball shaft module to rotate.
  • the ball shaft module has a free rotation function, so that the ultrasonic transducer fixing module can be driven by the ball shaft module to rotate, and the ball shaft module can adopt a variety of structures, for example, the ball shaft structure in the current car mobile phone bracket can be used. , which should not be restricted here. Therefore, by means of the ball-shaft connection, the ultrasonic transducer fixing modules in more directions can be realized, which is more conducive to positioning the ultrasonic transducer to the required precise position.
  • the second connecting member may include an inner movable ball 5 , an outer fixing ball 6 , a fixing ring 7 , a fixing member 8 (preferably a screw) and an ultrasonic transducer fixing module 9 .
  • the ultrasonic transducer fixing module 9 can fix the ultrasonic transducer 130, and the ultrasonic transducer 130 can be made of piezoelectric material or flexible transducer material.
  • the ultrasonic transducer fixing module 9 can expand and contract the sliding ring 10 according to actual needs, so as to adjust the far and near positions of the ultrasonic transducer 130 .
  • the ultrasonic transducer fixing module 9 In the state of the ultrasonic transducer fixing module 9 of FIG. 3A , the slip ring 10 is stretched to realize the ultrasonic transducer 130 at a remote position, and in the state of the ultrasonic transducer fixing module 9 of FIG. 3B , the slip ring 10 Contraction to achieve ultrasound transducer 130 in a closer position. Therefore, the ultrasonic transducer fixing module 9 can not only fix the ultrasonic transducer, which is convenient for operation, but also can use the sliding ring to expand and contract the position of the transducer, so that the nerve can be stimulated more accurately and individually. In some embodiments, the ultrasonic transducer fixing module can be made of materials such as metal or carbon fiber.
  • the movable ball shaft (or, the ball shaft module) includes an inner movable ball 5, an outer fixed ball 6 and a fixing member 8 (preferably a screw), the spherical surface of the inner movable ball 5 is in contact with the spherical surface of the outer fixed ball 6, and The inner movable ball 5 can be rotated relative to the outer fixed ball 6, and when adjusted to a suitable direction, the outer fixed ball 6 is tightened by rotating the fixing member 8, thereby fixing the position of the inner movable ball 5.
  • the ultrasonic transducer fixing module 9 is connected.
  • the ball shaft is connected to the ultrasonic transducer fixing module 9, and the direction of the ultrasonic transducer can be adjusted in multiple angles and multiple dimensions.
  • the outer surface of the inner movable ball 5 and the inner surface of the outer fixed ball 6 are frosted or provided with concave and convex points, which can increase the friction between the two balls, and is beneficial to any position.
  • Fixed movable ball axle the outer fixed ball 6 can have a certain elasticity, and the inner diameter can be reduced by using the fixed ring 7 and the fixing member 8, and the outer movable ball can be a solid ball and can be made of materials such as metal or carbon fiber.
  • the support rod that can slide up and down and can rotate 360°, the movable ball shaft that rotates at multiple angles, and the sliding ring realize that the ultrasonic transducer can be used in almost any
  • the adjustment process of the multi-angle and multi-dimensional directions of the position can also operate the position of the ultrasonic transducer simply, flexibly and accurately, realizing the functions of portability, stimulation and feedback.
  • peripheral nerves including facial nerves, cervical vagus nerves, etc.
  • central nervous system etc.
  • peripheral nerves including facial nerves, cervical vagus nerves, etc.
  • central nervous system etc.
  • peripheral nerves including facial nerves, cervical vagus nerves, etc.
  • ultrasound non-invasive medical technology is applied to peripheral nerves, better clinical results can be achieved in the treatment of some diseases.
  • Peripheral nerves are closely related to organ function and diseases, and ultrasound regulation of peripheral nerves can effectively interfere with inflammation, high Blood pressure, diabetes, obesity, and diseases of the gastrointestinal tract.
  • FIG. 4 shows a structural block diagram of an example of a head-mounted ultrasonic nerve stimulation system according to an embodiment of the present application.
  • the head-mounted ultrasonic nerve stimulation system 400 includes the head-mounted ultrasonic nerve stimulation device 100 and a display 420 .
  • the head-mounted ultrasonic nerve stimulation device 100 includes a head-mounted support 110, an ultrasonic transducer 130, and a connecting structure 120 connecting the head-mounted support 110 and the ultrasonic transducer 130, so that the wearer can receive ultrasound like a hat
  • the non-invasive treatment process can enhance the medical experience of ultrasound stimulation.
  • the ultrasound transducer 130 may collect nerve image information, the display 420 may display the nerve image information, and the ultrasound transducer 130 may also output an ultrasound nerve stimulation signal.
  • the ultrasonic transducer may adopt various types, and may perform different operation processes according to different operating parameters (for example, driving signals used to define the power, frequency, and waveform of the ultrasonic signal, etc.).
  • driving signals used to define the power, frequency, and waveform of the ultrasonic signal, etc.
  • the image detection function or the ultrasound diagnosis function
  • the regulation and stimulation function is performed under the action of some driving signals (eg, the second driving signal).
  • the doctor can view the nerve image information on the display through the ultrasonic transducer in the first working mode (for example, under the action of the first driving signal).
  • the specific position of the target point can be clearly seen on the display, which facilitates precise stimulation of the ultrasonic transducer under the second working mode (for example, under the action of the second driving signal).
  • the head-mounted ultrasonic nerve stimulation system 400 may further include an ultrasonic generator 430 electrically connected to the ultrasonic transducer 130 .
  • the ultrasonic generator 430 can generate driving signals (eg, corresponding to various types of operating parameters), and the ultrasonic transducer 130 can perform corresponding functional operations according to the driving signals input by the ultrasonic generator 430 , such as ultrasonic Detection function or ultrasound stimulation function.
  • the ultrasonic transducer 130 can collect nerve image information according to the first driving signal generated by the ultrasonic generator, for example, to explore the specific positions of peripheral nerves such as the subcutaneous nerve and the vagus nerve, and according to the second driving signal generated by the ultrasonic generator The signal outputs the ultrasonic nerve stimulation signal to achieve the function of precise positioning of the target point.
  • the ultrasonic generator may receive a user operation to update the drive signal in a preset drive signal set, where the preset drive signal set includes a first drive signal and a second drive signal.
  • the switching of ultrasonic detection and ultrasonic stimulation functions can be realized by a user operation for the ultrasonic generator.
  • the function of the ultrasonic generator that is, the function of generating a driving signal for the ultrasonic transducer
  • the ultrasonic transducer can be switched by operating the ultrasonic transducer. Detection function and ultrasound stimulation function.
  • the head-mounted bracket is further provided with a preset number of auxiliary supports (such as 17 in FIG. 2 ) for contacting the head of the wearer of the head-mounted bracket, an electrode array (such as 18 ) in FIG. 2 is arranged in a preset number of auxiliary supports to collect physiological feedback signals (or brain wave signals) of the wearer of the headset.
  • the display 420 can display the feedback result corresponding to the physiological feedback signal.
  • the electrode array is connected to a receiver (such as a mobile terminal such as a computer, special equipment, etc.) through a signal transmission cable 19. After the receiver performs signal filtering and conversion operations to obtain feedback results, the display of the receiver is displayed.
  • the corresponding feedback results are displayed on the Therefore, while stimulating nerves (for example, peripheral nerves), the operator can view the effect of nerve stimulation in real time (for example, the effect of ultrasonic regulation of peripheral nerves) through the display, which facilitates timely correction of the stimulation plan and ensures high quality nerve stimulation process.
  • stimulating nerves for example, peripheral nerves
  • the operator can view the effect of nerve stimulation in real time (for example, the effect of ultrasonic regulation of peripheral nerves) through the display, which facilitates timely correction of the stimulation plan and ensures high quality nerve stimulation process.
  • various types of feedback signals can also be captured in various ways, so that the operator can view and evaluate the effect of nerve stimulation in real time, such as EMG, eye movement and brain CT (Computed Tomography, electronic computed tomography), MR (Magnetic Resonance, magnetic resonance) imaging and other signals.
  • the embodiments of the present application provide a portable head-mounted ultrasonic stimulation nerve and brain wave feedback system, which has the advantages of non-invasive, safe and accurate, and can meet the needs of personalized ultrasonic non-invasive treatment and operation.
  • ultrasound can apply peripheral nerve stimulation to different organs (eg, heart, spleen, liver, pancreas, gallbladder, etc.), and by stimulating different organ targets can intervene in related diseases.
  • the nerve stimulation device in the embodiment of the present application is head-mounted, and the use process is simple and convenient, so that the person being stimulated can move freely, and the target point (ie, the nerve position) can be stimulated more quickly, accurately and individually. This makes it possible to improve the efficiency and success rate of ultrasound stimulation of peripheral nerves while increasing compliance.
  • the facial nerve and the cervical vagus nerve can be stimulated non-invasively, quickly and accurately through the ultrasonic transducer.
  • imaging means to provide real-time feedback on the effect of stimulation, which perfectly realizes the closed-loop stimulation and regulation of the ultrasonic nervous system.
  • the disclosed apparatus/terminal device and method may be implemented in other manners.
  • the apparatus/terminal device embodiments described above are only illustrative.
  • the division of the modules or units is only a logical function division. In actual implementation, there may be other division methods, such as multiple units. Or components may be combined or may be integrated into another system, or some features may be omitted, or not implemented.
  • the shown or discussed mutual coupling or direct coupling or communication connection may be through some interfaces, indirect coupling or communication connection of devices or units, and may be in electrical, mechanical or other forms.
  • the units described as separate components may or may not be physically separated, and components displayed as units may or may not be physical units, that is, may be located in one place, or may be distributed to multiple network units. Some or all of the units may be selected according to actual needs to achieve the purpose of the solution in this embodiment.
  • each functional unit in each embodiment of the present application may be integrated into one processing unit, or each unit may exist physically alone, or two or more units may be integrated into one unit.
  • the above-mentioned integrated units may be implemented in the form of hardware, or may be implemented in the form of software functional units.
  • the integrated modules/units if implemented in the form of software functional units and sold or used as independent products, may be stored in a computer-readable storage medium.
  • the present application can implement all or part of the processes in the methods of the above embodiments, and can also be completed by instructing the relevant hardware through a computer program.
  • the computer program can be stored in a computer-readable storage medium, and the computer When the program is executed by the processor, the steps of the foregoing method embodiments can be implemented.
  • the computer program includes computer program code, and the computer program code may be in the form of source code, object code, executable file or some intermediate form, and the like.
  • the computer-readable medium may include: any entity or device capable of carrying the computer program code, recording medium, U disk, removable hard disk, magnetic disk, optical disk, computer memory, read-only memory (ROM, Read-Only Memory) , Random Access Memory (RAM, Random Access Memory), electric carrier signal, telecommunication signal and software distribution medium, etc. It should be noted that the content contained in the computer-readable media may be appropriately increased or decreased according to the requirements of legislation and patent practice in the jurisdiction, for example, in some jurisdictions, according to legislation and patent practice, the computer-readable media Electric carrier signals and telecommunication signals are not included.

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Abstract

本申请实施例提供了一种头戴式超声神经刺激装置及系统，涉及医学设备技术领域，该装置包括头戴支架；超声换能器，用于输出超声神经刺激信号；连接结构，连接所述头戴支架和所述超声换能器，且用于调整所述头戴支架与所述超声换能器之间的相对位置。由此，佩戴者可以像戴帽子一样去佩戴头戴支架来接受神经刺激操作，佩戴者能够自由活动而得到较佳的超声医疗体验，并且超声换能器具有较大的操作位置范围，可以降低操作误差。

Description

头戴式超声神经刺激装置及系统 技术领域
本申请属于医学设备技术领域，尤其涉及一种头戴式超声神经刺激装置及系统。
 背景技术
物理性脑部刺激神经调控技术（电刺激、磁刺激等）为脑功能疾病患者提供了一种有效的临床治疗手段。
随着超声技术的发展，医学超声是一种无创诊疗技术，能够人体内形成聚焦点呈长椭圆形，这种特性也使得他获得良好的空间精度，靶向作用于特定区域组织。医学超声可以分为高强度聚焦超声和低强度聚焦超声，高强度聚焦超声是一种直接损毁病灶的治疗方式，而低强度聚焦超声在神经调控领域也起着重要作用。
但是，目前在使用超声无创医疗技术时，需要检查者手持超声换能器，浪费人力且操作不便，而被检查者更多时候需要躺在床上，无法自由活动且难以匹配超声换能器的操作位置，易导致较大的操作误差。
 技术问题
有鉴于此，本申请实施例提供了一种头戴式超声神经刺激装置及系统，以至少解决目前超声换能器操作不便且难以与被检查者匹配而易导致操作误差的问题。
 技术解决方案
根据本申请实施例的一方面，提供了一种头戴式超声神经刺激装置，包括：头戴支架；超声换能器，用于输出超声神经刺激信号；连接结构，连接所述头戴支架和所述超声换能器，且用于调整所述头戴支架与所述超声换能器之间的相对位置。
根据本申请实施例的另一方面，提供了一种头戴式超声神经刺激系统，包括：如上述的头戴式超声神经刺激装置；显示器；其中，所述头戴式超声神经刺激装置中的超声换能器用于采集神经图像信息；所述显示器用于显示所述神经图像信息。
 有益效果
本申请实施例采用的上述至少一个技术方案能够达到以下有益效果：
在本申请的头戴式超声神经刺激装置中，佩戴者可以像戴帽子一样去佩戴头戴支架来接受神经刺激操作，佩戴者能够自由活动而得到较佳的超声医疗体验，并且头戴支架和超声换能器之间通过连接结构连接，通过连接结构能够调整头戴支架与超声换能器之间的相对位置，使得超声换能器具有较大的操作位置范围，可以降低操作误差。
 附图说明
为了更清楚地说明本申请实施例中的技术方案，下面将对实施例或现有技术描述中所需要使用的附图作简单地介绍，显而易见地，下面描述中的附图仅仅是本申请的一些实施例，对于本领域普通技术人员来讲，在不付出创造性劳动的前提下，还可以根据这些附图获得其他的附图。
图1示出了根据本申请实施例的头戴式超声神经刺激装置的一示例的结构示意图；
图2示出了根据本申请实施例的头戴式超声神经刺激装置的一示例的结构示意图；
图3A示出了根据本申请实施例的超声换能器固定模块在第一状态下的结构示意图；
图3B示出了根据本申请实施例的超声换能器固定模块在第二状态下的结构示意图；
图4示出了根据本申请实施例的头戴式超声神经刺激系统的一示例的结构框图。
 本发明的实施方式
目前应用超声技术对人体组织进行刺激作用，通过产生几种效应来引起病变组织的改变,从而达到治疗的目的。这些超声所产生的效应主要是热效应、机械效应和空化效应。
在热效应的刺激作用机制中，超声波在传播过程中，由于媒质的粘滞性、导热性等引起部分的声能被媒质所吸收，结果转化为热能，并导致局部温度上升。组织受到这种热效应后，产生了某些反应，例如血管扩张、血液循环加快、组织代谢增高，从而促进病理产物的吸收消散。
在机械效应的刺激作用机制中，超声波在传播过程中，媒质中质点振动的机械效应引起某些细微组织的加速度、旋转、冲流等振动，从而起到按摩的作用，并增强了半透膜的弥散（即增强了通透性）、细胞的代谢功能和细胞的活力，对细胞的物质交换、组织营养也产生了较良好的影响。
在空化效应的刺激作用机制中，超声波在传播过程中，足够的超声强度遇到人体中某些液性组织时，将产生空化，能产生强度很高的微冲击波，可以改变或者破坏病变组织，从而达到治疗目的。
需说明的是，于本申请实施例中所公开的头戴式超声神经刺激装置及系统，主要涉及在穿戴式超声神经刺激装置或系统中各个组成部件的结构或连接关系，并可以采用各种效应的刺激作用机制，在此应不加限制。
以下描述中，为了说明而不是为了限定，提出了诸如特定系统结构、技术之类的具体细节，以便透彻理解本申请实施例。然而，本领域的技术人员应当清楚，在没有这些具体细节的其它实施例中也可以实现本申请。在其它情况中，省略对众所周知的系统、装置、电路以及方法的详细说明，以免不必要的细节妨碍本申请的描述。
为了说明本申请所述的技术方案，下面通过具体实施例来进行说明。
应当理解，当在本说明书和所附权利要求书中使用时，术语“包括”指示所描述特征、整体、步骤、操作、元素和/或组件的存在，但并不排除一个或多个其它特征、整体、步骤、操作、元素、组件和/或其集合的存在或添加。
还应当理解，在此本申请说明书中所使用的术语仅仅是出于描述特定实施例的目的而并不意在限制本申请。如在本申请说明书和所附权利要求书中所使用的那样，除非上下文清楚地指明其它情况，否则单数形式的“一”、“一个”及“该”意在包括复数形式。
还应当进一步理解，在本申请说明书和所附权利要求书中使用的术语“和/或”是指相关联列出的项中的一个或多个的任何组合以及所有可能组合，并且包括这些组合。
如在本说明书和所附权利要求书中所使用的那样，术语“如果”可以依据上下文被解释为“当...时”或“一旦”或“响应于确定”或“响应于检测到”。类似地，短语“如果确定”或“如果检测到[所描述条件或事件]”可以依据上下文被解释为意指“一旦确定”或“响应于确定”或“一旦检测到[所描述条件或事件]”或“响应于检测到[所描述条件或事件]”。
具体实现中，本申请实施例中描述的移动终端包括但不限于诸如具有触摸敏感表面(例如，触摸屏显示器和/或触摸板)的移动电话、膝上型计算机或平板计算机之类的其它便携式设备。还应当理解的是，在某些实施例中，上述设备并非便携式通信设备，而是具有触摸敏感表面(例如，触摸屏显示器和/或触摸板)的台式计算机。
另外，在本申请的描述中，术语“第一”、“第二”、“第三”等仅用于区分描述，而不能理解为指示或暗示相对重要性。
图1示出了根据本申请实施例的头戴式超声神经刺激装置的一示例的结构示意图。
如图1所示，头戴式超声神经刺激装置100包括头戴支架110、连接结构120和超声换能器130。
具体地，头戴支架110可以由佩戴者穿戴在头部，其可以是各种适合头部佩戴的造型结构，例如半环形支架或者环形支架，等等。
超声换能器130可以输出超声神经刺激信号，超声神经刺激信号的工作参数（例如，功率、频率和波形等）可以是预先设定的，并可以是多样化的超声神经刺激信号。应理解的是，超声换能器（也被称为，超声探头）是医学超声仪器设备的重要组成部分，其能完成在电能与机械能之间转换。
在本申请实施例的一些示例中，超声换能器130可以集成了超声发生功能，使得在超声换能器130能够独立自主地产生驱动信号（电信号）并输出相应的超声神经刺激信号（声信号）。在本申请实施例的另一些示例中，超声换能器130可以与超声发生器电连接，超声发生器（也被称为，超声波驱动电源），其可以将市电转换成与超声换能器相匹配的高频交流电信号（例如，各种参数类型的超声波电信号），以驱动超声波换能器工作。进而，超声换能器可以根据超声发生器所产生的驱动信号输出相应的超声神经刺激信号（声信号）。
连接结构120连接头戴支架110和超声换能器130，并且通过连接结构120可以调整头戴支架110与超声换能器130之间的相对位置。应理解的是，关于相对位置的调整方向，其可以是限制性的或多样化的（例如，可与头戴支架110之间呈任意角度的方向进行调整）。
在一些应用场景下，在佩戴者使用该头戴式超声神经刺激装置时，佩戴者不需要躺下，并只需要像戴帽子一样戴上头戴支架即可，操作非常方便，佩戴者具有较大的自由活动空间。此外，通过连接结构能够调整头戴支架与超声换能器之间的相对位置，使得超声换能器能够具有更多的作用位置，可以降低操作误差。
需说明的是，在本文中，头戴式超声神经刺激装置或系统的“佩戴者”或“用户”可以是各种身份，例如医生、患者等。在本文其他部分中所提及的术语“医生”和“患者”仅用作示例，并不旨在对佩戴者身份的限制，例如在一些情形下佩戴者可以佩戴头戴式超声神经刺激装置来对自己进行刺激操作，此时佩戴者既是医生又是患者。
图2示出了根据本申请实施例的头戴式超声神经刺激装置的一示例的结构示意图。
在本申请实施例的一些示例中，头戴支架110为可收缩式头戴支架。由此，使得头戴支架能够适配不同的佩戴者头部的大小，扩大了头戴式超声神经刺激装置的应用范围。此外，为了增加舒适性，可以在头戴支架110（其可以采用金属或碳材料等）的内面加用一些海绵等软性材料，以保护头皮，减少额外损伤。
结合图2中的示例，头戴支架110可以包括环形头圈14、头圈交叉部15、固定件16（优选为螺钉）和辅助支撑件17。具体地，环形头圈14可以分为前头圈部分和后头圈部分，前头圈部分和后头圈部分通过头圈交叉部15连接并存在重合的区域，利用头圈交叉部15可以调节头圈大小，例如如果前头圈部分和后头圈部分重合的区域越大，则头圈就越小。此外，在调节完成头圈大小后，可以通过固定件16来旋紧固定，使得头圈能与不同的头部大小相适合。这样，头戴支架110类似于一顶帽子，可被穿戴在头部，并能根据头部大小来适当调整大小，使与佩戴者头部完全适合。通过头圈穿戴在头部，能使超声换能器与佩戴者整合为一体，在进行超声刺激神经（例如，外周神经）时，整个过程不会约束佩戴者的活动自由。
在本申请实施例的一些示例中，在头戴支架的内圈设置有预设数量个用于与头戴支架的佩戴者的头部接触的辅助支撑件。由此，通过辅助支撑件也可以辅助支撑和固定头戴式超声神经刺激装置，使得头戴式超声神经刺激装置能够可靠、稳定地地固定在头戴支架的佩戴者（例如，患者）的头部。
结合图2中的示例，通过辅助支撑件17来辅助头圈完成头圈的固定操作，辅助支撑件17可以是弹性带，其协助承载整个装置的部分重量，并缓冲了头圈对头部的压迫。
进一步地，头戴式超声神经刺激装置可以包括电极器阵列，其被设置在预设数量个辅助支撑件中，并且通过电极器阵列可以采集头戴支架的佩戴者（例如，患者）的生理反馈信号。由此，相比于目前需要医生将多个电极器（或，电极片）依次贴在患者的头部，本申请实施例中只需要用户佩戴头架即可，简化了对头戴式超声神经刺激装置的刺激效果数据的采集过程。在一些实施方式中，辅助支撑件可采用橡皮等弹性材料，使得辅助支撑件具有弹性，并可以协助承载整个装置的一部分重量，缓冲了头戴支架对头部的压迫。
结合图2中的示例，可以在（例如，各个）辅助支撑件17上安装电极器，由于辅助支撑件呈弹性，使得辅助支撑件能够与头部紧密接触，电极器可有效感应脑电波的信号，以由电极器捕获各种反馈信号（例如，脑电波信号）的变化，便于分析神经刺激效果。
需说明的是，针对生理反馈信号的类型以及电极器阵列中电极器的排布方式，在此应不加限制，并可以是依据刺激效果数据来确定的。例如，在超声换能器输出超神神经刺激信号之后，通过电极器阵列可以采集各种反馈信号（例如，脑电波信号）的变化，并可以依据反馈信号的变化情况来分析神经刺激效果。由此，将电极器放置在固定条上，避免在头部额外再手动贴电极器，可以降低人为误差。
在本申请实施例的一个示例中，连接结构是在头戴支架与所述超声换能器之间的具有固定长度的连接结构。在本申请实施例的另一示例中，连接结构为可伸缩式连接结构，由此可以沿着连接结构的方向来调整头戴支架与超声换能器之间的相对位置。
在本申请实施例的一些示例中，连接结构包括连接杆，以及设置于连接杆的第一连接件和第二连接件。这里，通过第一连接件可以调节头戴支架相对于连接杆的位置，以及通过第二连接件可以调节超声换能器相对于连接杆的位置。由此，可以通过调节连接杆上的连接件来调整头戴支架与超声换能器之间的相对位置，使得超声换能器具有更大的操作位置范围。
结合图2中的示例，连接杆可以包括固定杆2、支撑杆3和固定件4（优选为螺钉），使得连接杆具有伸缩功能。这里，固定杆2可以是管状中空结构，固定杆2套在支撑杆3的外部，使得支撑杆3可在固定杆2内上下滑动或伸缩，并可通过固定件4穿过固定杆2上的孔洞（未示出）来压紧固定支撑杆3，从而调节头圈与超声换能器之间沿着连接杆方向的相对位置。此外，支撑杆3还可以在360度的范围内进行旋转。优选地，支撑杆3的表面磨砂或设有凹凸点，以使得固定件4能更牢靠地固定支撑杆3。在一些实施方式中，固定杆2和支撑杆3都可以选用金属或碳纤维等材料。
在本申请实施例的一些示例中，第一连接件包括用于夹持头戴支架的夹具。由此，可以通过夹具来夹持（例如，滑动移位来夹持）头戴支架的不同部位，实现多样化的头戴支架佩戴方式。
结合图2中的示例，第一连接件可以包括固定夹1，固定夹1可以固定（或夹持）头圈，同时固定夹1可根据实际需求而在头圈上移动（例如，滑动）位置，以夹持头戴支架110的不同位置。在一些实施方式中，固定夹1可选用金属或碳纤维等材料。
在本申请实施例的一些示例中，第二连接件可以包括超声换能器固定模块，用于伸缩调节超声换能器的位置。由此，可以实现具有更大的位置范围的超声换能器，有利于将超声换能器定位到所需求的精准位置。
进一步地，第二连接件中还可以设有球轴模块，用于固定超声换能器固定模块，使得超声换能器固定模块能够被球轴模块带动而进行旋转。这里，球轴模块具有自由旋转功能，使得超声换能器固定模块能够被球轴模块带动而进行旋转，并且球轴模块可以采用多样化的结构，例如可以采用目前车载手机支架中的球轴结构，在此应不加限制。由此，通过球轴连接的方式，可以实现在更多方向上的超声换能器固定模块，更有利于将超声换能器定位到所需求的精准位置。
结合图2中的示例，第二连接件可以包括内活动球5、外固定球6、固定圈7、固定件8（优选为螺钉）和超声换能器固定模块9。超声换能器固定模块9可以固定超声换能器130，超声换能器130可以采用压电材料或柔性换能器材料等。在本申请实施例的一些示例中，如图3A和3B所示，超声换能器固定模块9能够根据实际需求而伸缩滑动环10，以调节超声换能器130的远近位置。在图3A的超声换能器固定模块9的状态下，滑动环10伸展以实现在较远位置的超声换能器130，在图3B的超声换能器固定模块9的状态下，滑动环10收缩以实现在较近位置的超声换能器130。由此，超声换能器固定模块9既能固定住超声换能器，便于操作，又能利用滑动环来伸缩调节换能器的位置，可以更为准确、个体化地刺激神经。在一些实施方式中，超声换能器固定模块可选用金属或碳纤维等材料。
具体地，活动球轴（或，球轴模块）包括内活动球5、外固定球6和固定件8（优选为螺钉），内活动球5的球面与外固定球6的球面相接触，并且内活动球5可以相对外固定球6而进行旋转，并在调节到适宜方向时通过旋转固定件8使外固定球6收紧，从而固定内活动球5的位置，内活动球5的球面与超声换能器固定模块9连接。由此，实现了球轴连接超声换能器固定模块9，能够多角度、多维度地调节超声换能器的方向。在一些实施方式中，针对活动球轴的构造，内活动球5的外表面和外固定球6的内表面磨砂或设有凹凸点，能够增加两个球的摩擦力，并有利于在任意位置固定活动球轴。此外，外固定球6可以具有一定弹性，可以利用固定圈7及固定件8缩小内径，此外外活动球可以是实心球并可采用金属或碳纤维等材料。
在本申请实施例所提供的头戴式超声神经刺激装置中，利用能上下滑动且能旋转360°的支撑杆、多角度旋转的活动球轴和滑动环实现了超声换能器可以在几乎任意位置的多角度和多维度方向上的调节过程，还可以简单灵活且精准地操作超声换能器的位置，实现了集便携、刺激及反馈于一体的功能。
应理解的是，针对于本文中所描述的术语“神经”的类型可不作限制，其可以是各种能够通过超声技术进行作用的神经，例如外周神经（包括面部面神经、颈部迷走神经等）或中枢神经等。作为示例，当将超声无创医疗技术作用到外周神经时，针对一些疾病的治疗过程可以取得较佳的临床效果，外周神经与器官功能和疾病密切相关，而超声调控外周神经能有效干预炎症、高血压、糖尿病、肥胖以及胃肠道等疾病。
图4示出了根据本申请实施例的头戴式超声神经刺激系统的一示例的结构框图。
如图4所示，头戴式超声神经刺激系统400包括头戴式超声神经刺激装置100及显示器420。具体地，头戴式超声神经刺激装置100包括头戴支架110、超声换能器130和连接头戴支架110和超声换能器130的连接结构120，这样佩戴者可以像戴帽子一样去接受超声无创治疗过程，可以提升超声刺激的医疗体验。
具体地，超声换能器130可以采集神经图像信息，显示器420可以显示神经图像信息，并且超声换能器130还可以输出超声神经刺激信号。
在本申请实施例中，超声换能器可以采用各种类型，并且可以根据不同的工作参数（例如，用于定义超声波信号的功率、频率及波形等等）的驱动信号来执行不同的操作过程，例如基于一些驱动信号（例如，第一驱动信号）的作用下执行图像检测功能（或，超声诊断功能），在一些驱动信号（例如，第二驱动信号）的作用下执行调控刺激功能。
在本申请实施例的一些应用场景中，患者戴上头戴支架之后，医生通过在第一工作模式（例如，第一驱动信号作用）下的超声换能器可以在显示器上看到神经图像信息，可以清楚地在显示器上看到靶点的具体位置，便于在第二工作模式（例如，第二驱动信号作用）下的超声换能器进行精准刺激。
在本申请实施例的一些示例中，头戴式超声神经刺激系统400还可以包括与超声换能器130电连接的超声发生器430。具体地，超声发生器430可以产生（例如，对应各种工作参数类型的超声波的）驱动信号，超声换能器130可以根据超声发生器430所输入的驱动信号来进行相应的功能操作，例如超声检测功能或超声刺激功能。具体地，超声换能器130可以根据超声发生器所产生的第一驱动信号采集神经图像信息，例如，探查皮下面神经、迷走神经等外周神经的具体位置，以及根据超声发生器所产生的第二驱动信号输出超声神经刺激信号，实现目标靶点精准定位的作用。
在本申请实施例的一些示例中，超声发生器可以接收用户操作而在预设的驱动信号集中更新驱动信号，预设的驱动信号集包括第一驱动信号和第二驱动信号。由此，可以通过针对超声发生器的用户操作来实现切换超声检测和超声刺激功能。在本申请实施例的另一些示例中，超声发生器的功能（即产生针对超声波换能器的驱动信号的功能）被集成在超声换能器中，可以通过操作超声换能器来实现切换超声检测功能和超声刺激功能。
在本申请实施例的一些示例中，头戴支架还设置有用于与头戴支架的佩戴者的头部接触的预设数量个辅助支撑件（如图2中的17），电极器阵列（如图2中的18）被设置在预设数量个辅助支撑件中以采集头戴支架的佩戴者的生理反馈信号（或脑电波信号）。进而，显示器420可以显示生理反馈信号所对应的反馈结果。作为示例，电极器阵列通过信号传输线缆19连接至接收器（诸如计算机、专用设备之类的移动终端），由接收器进行信号滤波及转换等操作而得到反馈结果之后，在接收器的显示器上显示相应的反馈结果。由此，在对神经（例如，外周神经）进行刺激的同时，操作者可以通过显示器来实时查看神经刺激的效果（例如，超声调控外周神经的效果），便于及时矫正刺激方案，可以保障高质量的神经刺激过程。
需说明的是，除了可以将电极器阵列所采集的信号作为反馈信号之外，还可以多种方式来捕获各种类型的反馈信号，以使得操作者能实时查看并评估神经刺激的效果，例如肌电、眼动及颅脑CT（Computed Tomography, 电子计算机断层扫描）、MR（Magnetic Resonance, 核磁共振）影像学等信号。
通过本申请实施例，提供了一种头戴便携式超声刺激神经及脑电波反馈系统，具备无创、安全、准确的优点，能够满足个性化超声无创治疗及操作的需求。应理解的是，由于超声刺激的无创性，所以超声能应用不同器官（例如，心脏、脾脏、肝脏、胰腺、胆囊等）的外周神经刺激，并且通过刺激不同器官靶点能够干预相关疾病。此外，本申请实施例中的神经刺激装置是头戴式的，使用过程简单、便捷，使得被刺激者能自由活动，且能够更快速、准确及个体化刺激靶点（即，神经位置），使得在增加依从性的同时，还可以提高超声刺激外周神经的效率和成功率。
在本申请实施例的一些应用场景下，在患者佩戴上头戴支架之后，通过超声换能器能够无创、快速且精准地刺激面部面神经和颈部迷走神经，同时利用脑电、肌电、眼动、以及影像学手段等信号对刺激的效果进行实时反馈，完美实现了超声神经系统的闭环刺激与调控。
所属领域的技术人员可以清楚地了解到，为了描述的方便和简洁，仅以上述各功能单元、模块的划分进行举例说明，实际应用中，可以根据需要而将上述功能分配由不同的功能单元、模块完成，即将所述装置的内部结构划分成不同的功能单元或模块，以完成以上描述的全部或者部分功能。实施例中的各功能单元、模块可以集成在一个处理单元中，也可以是各个单元单独物理存在，也可以两个或两个以上单元集成在一个单元中，上述集成的单元既可以采用硬件的形式实现，也可以采用软件功能单元的形式实现。另外，各功能单元、模块的具体名称也只是为了便于相互区分，并不用于限制本申请的保护范围。上述系统中单元、模块的具体工作过程，可以参考前述方法实施例中的对应过程，在此不再赘述。
在上述实施例中，对各个实施例的描述都各有侧重，某个实施例中没有详述或记载的部分，可以参见其它实施例的相关描述。
本领域普通技术人员可以意识到，结合本文中所公开的实施例描述的各示例的单元及算法步骤，能够以电子硬件、或者计算机软件和电子硬件的结合来实现。这些功能究竟以硬件还是软件方式来执行，取决于技术方案的特定应用和设计约束条件。专业技术人员可以对每个特定的应用来使用不同方法来实现所描述的功能，但是这种实现不应认为超出本申请的范围。
在本申请所提供的实施例中，应该理解到，所揭露的装置/终端设备和方法，可以通过其它的方式实现。例如，以上所描述的装置/终端设备实施例仅仅是示意性的，例如，所述模块或单元的划分，仅仅为一种逻辑功能划分，实际实现时可以有另外的划分方式，例如多个单元或组件可以结合或者可以集成到另一个系统，或一些特征可以忽略，或不执行。另一点，所显示或讨论的相互之间的耦合或直接耦合或通讯连接可以是通过一些接口，装置或单元的间接耦合或通讯连接，可以是电性，机械或其它的形式。
所述作为分离部件说明的单元可以是或者也可以不是物理上分开的，作为单元显示的部件可以是或者也可以不是物理单元，即可以位于一个地方，或者也可以分布到多个网络单元上。可以根据实际的需要选择其中的部分或者全部单元来实现本实施例方案的目的。
另外，在本申请各个实施例中的各功能单元可以集成在一个处理单元中，也可以是各个单元单独物理存在，也可以两个或两个以上单元集成在一个单元中。上述集成的单元既可以采用硬件的形式实现，也可以采用软件功能单元的形式实现。
所述集成的模块/单元如果以软件功能单元的形式实现并作为独立的产品销售或使用时，可以存储在一个计算机可读取存储介质中。基于这样的理解，本申请实现上述实施例方法中的全部或部分流程，也可以通过计算机程序来指令相关的硬件来完成，所述的计算机程序可存储于一计算机可读存储介质中，该计算机程序在被处理器执行时，可实现上述各个方法实施例的步骤。其中，所述计算机程序包括计算机程序代码，所述计算机程序代码可以为源代码形式、对象代码形式、可执行文件或某些中间形式等。所述计算机可读介质可以包括：能够携带所述计算机程序代码的任何实体或装置、记录介质、U盘、移动硬盘、磁碟、光盘、计算机存储器、只读存储器（ROM，Read-Only Memory）、随机存取存储器（RAM，Random Access Memory）、电载波信号、电信信号以及软件分发介质等。需要说明的是，所述计算机可读介质包含的内容可以根据司法管辖区内立法和专利实践的要求进行适当的增减，例如在某些司法管辖区，根据立法和专利实践，计算机可读介质不包括电载波信号和电信信号。
以上所述实施例仅用以说明本申请的技术方案，而非对其限制；尽管参照前述实施例对本申请进行了详细的说明，本领域的普通技术人员应当理解：其依然可以对前述各实施例所记载的技术方案进行修改，或者对其中部分技术特征进行等同替换；而这些修改或者替换，并不使相应技术方案的本质脱离本申请各实施例技术方案的精神和范围，均应包含在本申请的保护范围之内。

Claims (11)

  1. 一种头戴式超声神经刺激装置，其特征在于，包括：
    头戴支架；
    超声换能器，用于输出超声神经刺激信号；
    连接结构，连接所述头戴支架和所述超声换能器，且用于调整所述头戴支架与所述超声换能器之间的相对位置。
  2. 如权利要求1所述的头戴式超声神经刺激装置，其特征在于，所述头戴支架为可收缩式头戴支架，和/或所述连接结构为可伸缩式连接结构。
  3. 如权利要求1所述的头戴式超声神经刺激装置，其特征在于，所述连接结构包括连接杆，以及设置于所述连接杆的第一连接件和第二连接件，
    其中，所述第一连接件用于调节所述头戴支架相对于所述连接杆的位置，以及所述第二连接件用于调节所述超声换能器相对于所述连接杆的位置。
  4. 如权利要求3所述的头戴式超声神经刺激装置，其特征在于，所述第一连接件包括用于夹持所述头戴支架的夹具。
  5. 如权利要求3所述的头戴式超声神经刺激装置，其特征在于，所述第二连接件包括：
    超声换能器固定模块，用于伸缩调节所述超声换能器的位置。
  6. 如权利要求5所述的头戴式超声神经刺激装置，其特征在于，所述第二连接件还包括：
    球轴模块，用于固定所述超声换能器固定模块，使得所述超声换能器固定模块能够被所述球轴模块带动而进行旋转。
  7. 如权利要求1所述的头戴式超声神经刺激装置，其特征在于，在所述头戴支架的内圈设置有预设数量个用于与头戴支架的佩戴者的头部接触的辅助支撑件。
  8. 一种头戴式超声神经刺激系统，其特征在于，包括：
    如权利要求1-7中任一项所述的头戴式超声神经刺激装置；
    显示器；
    其中，所述头戴式超声神经刺激装置中的超声换能器用于采集神经图像信息；
    所述显示器用于显示所述神经图像信息。
  9. 如权利要求8所述的头戴式超声神经刺激系统，其特征在于，所述头戴式超声神经刺激系统还包括：
    超声发生器，与所述超声换能器电连接，用于产生与所述超声换能器相匹配的驱动信号；
    其中，所述超声换能器用于根据所述超声发生器所产生的第一驱动信号采集神经图像信息，以及根据所述超声发生器所产生的第二驱动信号输出超声神经刺激信号。
  10. 如权利要求9所述的穿戴式超声神经刺激系统，其特征在于，所述超声发生器用于接收用户操作而在预设的驱动信号集中更新驱动信号，所述预设的驱动信号集包括所述第一驱动信号和所述第二驱动信号。
  11. 如权利要求8所述的头戴式超声神经刺激系统，其特征在于，所述头戴支架的内圈设置有预设数量个用于与头戴支架的佩戴者的头部接触的辅助支撑件，
    其中，所述头戴式超声神经刺激装置还包括被设置在所述预设数量个辅助支撑件中的电极器阵列，以用于采集头戴支架的佩戴者的生理反馈信号；
    所述显示器用于显示所述生理反馈信号所对应的反馈结果。
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