WO2021248914A1 - 一种脑力疲劳干预设备及干预方法 - Google Patents

一种脑力疲劳干预设备及干预方法 Download PDF

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Publication number
WO2021248914A1
WO2021248914A1 PCT/CN2021/073000 CN2021073000W WO2021248914A1 WO 2021248914 A1 WO2021248914 A1 WO 2021248914A1 CN 2021073000 W CN2021073000 W CN 2021073000W WO 2021248914 A1 WO2021248914 A1 WO 2021248914A1
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magnetic stimulation
intervention
generator
ecg
current generator
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PCT/CN2021/073000
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English (en)
French (fr)
Inventor
王慧泉
赵喆
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深圳市太美亚电子科技有限公司
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Publication of WO2021248914A1 publication Critical patent/WO2021248914A1/zh
Priority to ZA2022/06825A priority Critical patent/ZA202206825B/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00—Magnetotherapy
    • A61N2/002—Magnetotherapy in combination with another treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H39/00—Devices for locating or stimulating specific reflex points of the body for physical therapy, e.g. acupuncture
    • A61H39/002—Using electric currents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M21/02—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis for inducing sleep or relaxation, e.g. by direct nerve stimulation, hypnosis, analgesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00—Magnetotherapy
    • A61N2/004—Magnetotherapy specially adapted for a specific therapy
    • A61N2/006—Magnetotherapy specially adapted for a specific therapy for magnetic stimulation of nerve tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00—Magnetotherapy
    • A61N2/02—Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2230/00—Measuring physical parameters of the user
    • A61H2230/04—Heartbeat characteristics, e.g. E.G.C., blood pressure modulation
    • A61H2230/06—Heartbeat rate
    • A61H2230/065—Heartbeat rate used as a control parameter for the apparatus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M2021/0005—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
    • A61M2021/0027—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus by the hearing sense
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M2021/0005—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
    • A61M2021/0072—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus with application of electrical currents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00—Measuring parameters of the user
    • A61M2230/04—Heartbeat characteristics, e.g. ECG, blood pressure modulation
    • A61M2230/06—Heartbeat rate only

Definitions

  • the invention relates to the technical field of medical rehabilitation and health care, in particular to a mental fatigue intervention device and an intervention method.
  • the best way to relieve mental fatigue is to sleep.
  • Sufficient sleep time and good sleep quality are essential to ensure people's normal physical and mental health, cognitive ability and work performance.
  • the incidence of insomnia among Chinese nationals is 38%, and the elderly are a high incidence of apnea, with a proportion of 40%.
  • the incidence of insomnia is 20% in children and adults. Sleep disturbance has become a major factor restricting the harmony of modern society.
  • PSG polysomnography
  • the mental fatigue intervention devices on the market usually use a single acoustic stimulation, electrical stimulation or magnetic stimulation technique to achieve the purpose of relieving brain fatigue, promoting sleep or treating insomnia.
  • the existing mental fatigue intervention devices include: using five-tone music, compound running water sounds, bird calls, tidal water sounds, wind sounds, etc., to combine into a composite sound, and use the composite sound for the patient to relax and delight the user. Avoid hearing loss caused by high-intensity noise, and achieve the purpose of guiding attention and improving sleep.
  • the electrical stimulation generator By attaching a single-point electrode to the skin of the Shenmen acupoint on the human body, the electrical stimulation generator sends out pulsed square waves to improve Symptoms of insomnia and anxiety.
  • the magnetic field focusing method by combining the magnets in a certain order, using the principle that the magnetic lines of force will repel each other when the magnetic poles of the same name are close to each other, the magnetic lines of force are gathered in the required area, effectively increasing the intensity of magnetic field stimulation, thereby affecting the metabolic activity of human tissues , To achieve the purpose of improving sleep quality.
  • the existing mental fatigue intervention equipment can improve mental fatigue to a certain extent and achieve the purpose of improving sleep quality, it uses a single physical intervention method, so it has the disadvantage of low intervention accuracy.
  • the present invention provides the following solutions:
  • a mental fatigue intervention device comprising: a headband body and a front DC current generator, a rear DC current generator, a left magnetic stimulation generator, a right magnetic stimulation generator, and a left electrocardiogram collection set on the headband body Electrode, right ECG collection electrode, left earphone, right earphone and circuit board;
  • the front direct current generator is located in the middle of the forehead; the rear direct current generator is located behind the head; the left earphone is arranged on the left side of the headband body, and the right earphone is arranged on the right side of the headband body.
  • Side; the left side of the front direct current generator is provided with a left magnetic stimulation generator, and the right side of the front direct current generator is provided with a right magnetic stimulation generator; between the left magnetic stimulation generator and the left earphone
  • a left ECG collection electrode is set; a right ECG collection electrode is set between the right magnetic stimulation generator and the right earphone; the front direct current generator, the rear direct current generator, and the left magnetic stimulation are generated
  • the device, the right magnetic stimulation generator, the left ECG collection electrode, the right ECG collection electrode, the left earphone, and the right earphone are all electrically connected to the circuit board.
  • the headband body includes a front hoop body and a connecting part; the front hoop body is an unclosed ring hoop; the ends of the front hoop body are connected through the connecting part; the front direct current is generated
  • the device, the left magnetic stimulation generator, the right magnetic stimulation generator, the left ECG collection electrode, the right ECG collection electrode, the left earphone and the right earphone are all set in the front hoop
  • the inner side of the body; the rear DC current generator is arranged on the inner side of the connecting part; the circuit board is arranged inside the connecting part.
  • the front direct current generator and the rear direct current generator are both direct current stimulation electrodes.
  • the left magnetic stimulation generator and the right magnetic stimulation generator are both magnetic stimulation coils.
  • the left ECG collection electrode and the right ECG collection electrode are both single-lead ECG electrodes.
  • the headband body is a headband body.
  • the mental fatigue intervention device further includes an upper computer; the upper computer is wirelessly connected with the circuit board.
  • the circuit board includes a collection module, an intervention output module, a power management module, and a transmission processing module;
  • the collection module is used to control the left ECG collection electrode and the right ECG collection electrode to collect the wearer’s ECG signal;
  • the intervention output module is used to control the front direct current generator and the rear direct current generator to generate electrical intervention signals, and to control the left magnetic stimulation generator and the right magnetic stimulation generator to generate magnetic Intervention signal and control the left earphone and the right earphone to generate an acoustic intervention signal;
  • the power management module is used to manage the power supply;
  • the transmission processing module is used to transmit and process the ECG signal.
  • the transmission processing module is a power amplifier.
  • the present invention also provides a mental fatigue intervention method, which is used in the mental fatigue intervention device described above; the method includes:
  • the front DC current generator and the rear DC current generator are controlled by the brain fatigue degree signal to generate electrical intervention signals, the left magnetic stimulation generator and the right magnetic stimulation generator are controlled to generate magnetic intervention signals, and the left and right earphones are controlled to generate acoustic intervention. Signal.
  • the present invention provides a mental fatigue intervention device and an intervention method.
  • the mental fatigue intervention device includes a headband body and a front DC current generator, a rear DC current generator, a left magnetic stimulation generator, and a headband body arranged on the headband body.
  • the wearer’s ECG signal is obtained from the ECG collection electrode;
  • the direct current generator generates direct current to achieve transcranial electrical stimulation;
  • the earphone plays audio to achieve sound intervention of brain fatigue;
  • the magnetic stimulation generator generates weak magnetic stimulation to achieve brain stimulation Repeated continuous magnetic stimulation of major acupoints such as the frontal area and Yiming (behind the ear).
  • the invention adopts three physical stimuli of sound, electricity and magnetic at the same time, realizes compound intervention, and has high intervention precision, thereby achieving a better mental fatigue relieving effect more stably, faster and to a greater extent, and improving sleep
  • Figure 1 is a structural diagram of a mental fatigue intervention device in one direction according to an embodiment of the present invention
  • FIG. 2 is a structural diagram of a mental fatigue intervention device in another direction according to an embodiment of the present invention.
  • FIG. 3 is a schematic diagram of the structure of a circuit board according to an embodiment of the present invention.
  • FIG. 4 is a schematic circuit diagram of a collection module according to an embodiment of the present invention.
  • FIG. 5 is a schematic diagram of a direct current electrical stimulation output intervention drive circuit in an intervention output module of an embodiment of the present invention
  • FIG. 6 is a schematic diagram of a voltage-current conversion circuit of a magnetic stimulation module in an intervention output module according to an embodiment of the present invention
  • Fig. 7 is a schematic circuit diagram of a power management module according to an embodiment of the present invention.
  • Fig. 8 is a schematic circuit diagram of a transmission processing module according to an embodiment of the present invention.
  • Fig. 9 is a flowchart of a mental fatigue intervention method in a specific embodiment of the present invention.
  • Fig. 1 is a structural diagram of a mental fatigue intervention device in one direction according to an embodiment of the present invention
  • Fig. 2 is a structural diagram of a mental fatigue intervention device in another direction according to an embodiment of the present invention.
  • the mental fatigue intervention device of this embodiment includes: a headband body and a front DC current generator 1, a rear DC current generator 2, and a left magnetic stimulation generator provided on the headband body 3.
  • Right magnetic stimulation generator 4 left ECG collection electrode 5, right ECG collection electrode 6, left earphone 7, right earphone 8 and circuit board 9.
  • the front direct current generator 1 is located in the middle of the forehead; the rear direct current generator 2 is located behind the head; the left earphone 7 is arranged on the left side of the headband body, and the right earphone 8 is arranged on the head
  • the right side of the hoop body; the left side of the front DC current generator 1 is provided with a left magnetic stimulation generator 3, and the right side of the front DC current generator 1 is provided with a right magnetic stimulation generator 4; the left magnetic stimulation occurs
  • a left ECG collection electrode 5 is arranged between the device 3 and the left earphone 7; a right ECG collection electrode 6 is arranged between the right magnetic stimulation generator 4 and the right earphone 8; the front DC current generator 1 ,
  • the rear direct current generator 2 the left magnetic stimulation generator 3, the right magnetic stimulation generator 4, the left ECG collection electrode 5, the right ECG collection electrode 6, the left earphone 7.
  • the right earphone 8 is electrically connected to the circuit board 9.
  • the headband body includes a front hoop body 10 and a connecting portion 11; the front hoop body 10 is an unclosed ring hoop; the end of the front hoop body 10 is connected through the Section 11 is connected; the front direct current generator 1, the left magnetic stimulation generator 3, the right magnetic stimulation generator 4, the left ECG collection electrode 5, the right ECG collection electrode 6, the The left earphone 7 and the right earphone 8 are both arranged on the inner side of the front hoop body 10; the rear direct current generator 2 is arranged on the inner side of the connecting portion 11; the circuit board 9 is arranged on the inner side of the connecting portion 11; ⁇ 11 ⁇ The interior of section 11.
  • the front direct current generator 1 and the rear direct current generator 2 are both direct current stimulation electrodes.
  • the left magnetic stimulation generator 3 and the right magnetic stimulation generator 4 are both magnetic stimulation coils.
  • the left ECG collection electrode 5 and the right ECG collection electrode 6 are both single-lead ECG electrodes.
  • the headband body is a portable headband body.
  • the mental fatigue intervention device further includes an upper computer; the upper computer is wirelessly connected to the circuit board 9.
  • the communication mode between the host computer and the circuit board 9 is WiFi wireless communication.
  • the upper computer is used to control the sound card and the upper computer control software.
  • the host computer control software together with the sound card, controls the generation of music signals, and together with the circuit board 9 controls the magnetic stimulation generating circuit to generate magnetic signals.
  • the host computer may be a computer.
  • the host computer control software further includes a physiological data analysis module, which comprehensively analyzes the ECG signals collected by the received ECG collection electrodes to obtain the wearer's rhythm and the degree of brain fatigue.
  • the upper computer control software determines an instant and fast sound intervention method, a stable and effective electrical stimulation intervention program, and a magnetic stimulation intervention program with long-term improvement functions according to the wearer's rhythm and the degree of brain fatigue.
  • FIG. 3 is a schematic structural diagram of a circuit board of an embodiment of the present invention.
  • the circuit board 9 includes a collection module 901, an intervention output module 902, a power management module 903, and a transmission processing module 904 .
  • the circuit schematic diagram of the acquisition module 901 is shown in FIG. 4.
  • ELE_RA, ELE_LA, ELE_LL are the analog signal input points of the ECG acquisition, the ECG signal is analog input, and then the analog to digital conversion is realized through U1.
  • the intervention output module 902 includes a two-part circuit structure. The first part is a direct current stimulation output intervention drive circuit, as shown in Figure 5.
  • FIG. 5 there are CLR, LATCH, SCLK, DIN, SDO receiving and transmitting the information of the processing module to change the IOUT current.
  • the size of the output; the second part is the voltage-current conversion circuit of the magnetic stimulation module, as shown in Figure 6.
  • the voltage signal in Figure 6 is input through R8, and then after U4A, U0A and Q1, a certain current signal is output to drive the magnetic Stimulate the coil.
  • the circuit principle diagram of the power management module 903 is shown in FIG. 7, and the circuit principle diagram of the transmission processing module 904 is shown in FIG. 8.
  • the collection module 901 is used to control the left ECG collection electrode 5 and the right ECG collection electrode 6 to collect the ECG signals of the wearer; the intervention output module 902 is used to control the front DC current generator 1
  • the posterior direct current generator 2 adopts transcranial direct current stimulation (tDCS) to perform direct current stimulation on the prefrontal cortex of the brain to generate electrical intervention signals and control the left magnetic stimulation generator 3 and all
  • the right magnetic stimulation generator 4 adopts a method of weak-intensity magnetic stimulation on the forehead and Yiming acupuncture points to generate magnetic intervention signals and control the left earphone 7 and the right earphone 8 to use pink noise and soothing music loops to play
  • the power management module 903 is used to manage the power supply and control the transcranial electrical stimulation (tDCS) generating circuit to generate electrical signals; the transmission processing module 904 is used to transmit and process the ECG signal .
  • the transmission processing module 904 is a power amplifier.
  • the left earphone 7 and the right earphone 8 are both high-quality earphones; the left earphone 7 is arranged at the bottom of the left T-shaped area of the headband body; the right earphone 8 is arranged at the bottom of the T-shaped area on the right side of the headband body.
  • the mental fatigue intervention equipment used in this implementation uses a magnetic stimulation generator with magnetic stimulation intervention to produce weak magnetic stimulation on the forehead and Yiming acupoints; uses a direct current generator with electrical stimulation intervention to provide transcranial electrical stimulation (tDCS)
  • tDCS transcranial electrical stimulation
  • the prefrontal cortex of the brain is stimulated by direct current; the ECG collecting electrodes used to obtain the physiological electrical signals of the wearer are used to collect the wearer’s ECG information; the earphones using acoustic stimulation intervention methods play pink noise and soothing music in a loop, so that sound is used at the same time.
  • the three stimulus intervention methods of, electrical, and magnetic realize the detection and relief of the wearer's mental fatigue, realize the compound intervention, thereby improve the accuracy of intervention, and achieve the purpose of mentally detecting mental fatigue and improving the sleep state.
  • the present invention also provides a mental fatigue intervention method, which is used in the mental fatigue intervention device described above; the method includes:
  • the front DC current generator 1 and the rear DC current generator 2 are controlled by the brain fatigue degree signal to generate electrical intervention signals, the left magnetic stimulation generator 3 and the right magnetic stimulation generator 4 are controlled to generate magnetic intervention signals, and the left earphone is controlled 7 and right earphone 8 generate acoustic intervention signals.
  • FIG. 9 is a flowchart of the mental fatigue intervention method in a specific embodiment of the present invention.
  • the obtained ECG signal is transferred to the collection module 901 of the circuit board 9.
  • the transmission processing module 904 of the circuit board 9 communicates with the upper computer to transmit the obtained ECG signal to the upper computer (computer); the computer controls the upper computer software to process and analyze the obtained ECG signal to obtain the wearer's rhythm and the degree of brain fatigue
  • the upper computer software determines the comprehensive intervention plan of instant and fast sound intervention, stable and effective electrical stimulation intervention and magnetic stimulation intervention with long-term improvement function; the computer transmits the formulated plan to the transmission processing module 904 of the circuit board 9.
  • the computer controls the sound card to generate corresponding music signals
  • the intervention output module 902 drives the left earphone 7 and the right earphone 8 to play the cyclic pink noise + soothing music set in the scheme.
  • the host computer control software and power management module 903 control the magnetic stimulation generating circuit to generate corresponding magnetic stimulation signals.
  • the intervention output module 902 drives the magnetic stimulation coil to generate magnetic stimulation at acupoints such as the forehead and Yiming.
  • the power management module 903 controls the tDCS electrical stimulation circuit to generate corresponding DC electrical stimulation signals.
  • the intervention output module 902 controls the DC electrical stimulation electrodes to perform cathodic electrical stimulation on the prefrontal cortex of the brain, thereby achieving precision and efficiency. The purpose of the intervention.
  • Such three intervention methods are carried out at the same time, which improves the accuracy of the intervention and achieves the purpose of alleviating the wearer's mental fatigue, promoting sleep, and alleviating the symptoms of insomnia.

Abstract

本发明公开了一种脑力疲劳干预设备及干预方法。所述脑力疲劳干预设备包括：头箍本体和设置在头箍本体上的前、后直流电流发生器，左、右磁刺激发生器，左、右心电采集电极，左、右耳机，以及电路板；前、后直流电流发生器分别位于前额中部和脑后；左、右耳机分别设置在头箍本体的左侧和右侧；前直流电流发生器的左侧设置左磁刺激发生器，前直流电流发生器的右侧设置右磁刺激发生器；左磁刺激发生器与左耳机之间设置左心电采集电极；右磁刺激发生器与右耳机之间设置右心电采集电极；电路板均与直流电流发生器、磁刺激发生器、心电采集电极和耳机电连接。本发明采用复合干预手段实现了脑力疲劳干预，提高了干预精准度。

Description

一种脑力疲劳干预设备及干预方法
本申请要求于2020年06月11日提交中国专利局、申请号为202010528331.8、发明名称为“一种脑力疲劳干预设备及干预方法”的中国专利申请的优先权，其全部内容通过引用结合在本申请中。
技术领域
本发明涉及医疗康复保健技术领域，特别是涉及一种脑力疲劳干预设备及干预方法。
背景技术
脑力疲劳的最好的缓解方式就是睡觉，充足的睡眠时间和良好的睡眠质量对于保证人们正常的身心健康、认知能力和工作表现至关重要。然而，中国国民的失眠发生率为38％，老人是呼吸暂停病症的高发人群，比例达40％，此外，儿童、成人发病率各为20％。睡眠障碍成为制约现代社会和谐的一个主要因素。
人类的睡眠中，在新陈代谢等一切生理功能活动下降的同时，机体处于保护性抑制状态，可以使疲劳的细胞得以修复。此外，睡眠时，合成代谢大于分解代谢，为机体储备能量物质及营养物质，使人们恢复体力和精力，以保证白天的劳动效率。
实现脑疲劳的缓解关键技术主要可分为两个部分：脑疲劳度监测和脑疲劳缓解的干预手段。临床上多采用多导睡眠监护仪(PSG)作为睡眠分期和脑疲劳状态评估，其价格昂贵、部署复杂、受试者体验较差，很难大规模采用。
目前，市场上存在的脑力疲劳干预设备，通常使用单一的声刺激、电刺激或磁刺激手法以达到缓解脑疲劳、促进睡眠或治疗失眠的目的。例如，现有的脑力疲劳干预设备有：采用五音律乐曲复合流水声、鸟叫声、潮水声、风声等组合成一个复合的声音，并将该复合声供患者使用，让使用者舒缓愉悦，避免高强度的噪声导致的听力下降，达到引导注意力、改善睡眠状态的目的。采用经皮电刺激神门穴治疗失眠和焦虑的装置，对目标穴 位进行精准刺激，通过将单穴位电极贴附在人体神门穴表面皮肤，通过电刺激发生器发出脉冲方波，用于改善失眠和焦虑症状。采用磁场聚焦方法，通过将磁体按照一定的顺序进行组合，利用同名磁极相互靠近时磁力线会相互排斥的原理，将磁力线聚集在所需的区域，有效提高磁场刺激强度，从而影响人体组织的代谢活动，达到改善睡眠质量地目的。
由此可知，现有的脑力疲劳干预设备虽然能在一定程度上改善脑力疲劳，能达到改善睡眠质量的目的，但是由于采用的都是单一物理干预手段，因此存在干预精准度低的缺点。
发明内容
基于此，有必要提供一种复合干预手段的脑力疲劳干预设备及干预方法，以提高干预精准度，从而更稳定、更快速、更大程度的达到更好的脑力疲劳缓解效果，提高睡眠质量。
为实现上述目的，本发明提供了如下方案：
一种脑力疲劳干预设备，包括：头箍本体和设置在所述头箍本体上的前直流电流发生器、后直流电流发生器、左磁刺激发生器、右磁刺激发生器、左心电采集电极、右心电采集电极、左耳机、右耳机和电路板；
所述前直流电流发生器位于前额中部；所述后直流电流发生器位于脑后；所述左耳机设置在所述头箍本体的左侧，所述右耳机设置在所述头箍本体的右侧；所述前直流电流发生器的左侧设置左磁刺激发生器，所述前直流电流发生器的右侧设置右磁刺激发生器；所述左磁刺激发生器与所述左耳机之间设置左心电采集电极；所述右磁刺激发生器与所述右耳机之间设置右心电采集电极；所述前直流电流发生器、所述后直流电流发生器、所述左磁刺激发生器、所述右磁刺激发生器、所述左心电采集电极、所述右心电采集电极、所述左耳机、所述右耳机均与所述电路板电连接。
可选的，所述头箍本体包括前箍体和连接部；所述前箍体为不封闭的环形箍；所述前箍体的端部通过所述连接部连接；所述前直流电流发生器、所述左磁刺激发生器、所述右磁刺激发生器、所述左心电采集电极、所述右心电采集电极、所述左耳机和所述右耳机均设置在所述前箍体的内侧； 所述后直流电流发生器设置在所述连接部的内侧；所述电路板设置在所述连接部的内部。
可选的，所述前直流电流发生器和所述后直流电流发生器均为直流电刺激电极。
可选的，所述左磁刺激发生器和所述右磁刺激发生器均为磁刺激线圈。
可选的，所述左心电采集电极和所述右心电采集电极均为单导心电电极。
可选的，所述头箍本体为头戴式箍体。
可选的，所述脑力疲劳干预设备，还包括上位机；所述上位机与所述电路板无线连接。
可选的，所述电路板包括采集模块、干预输出模块、电源管理模块和传输处理模块；所述采集模块用于控制所述左心电采集电极和所述右心电采集电极采集佩戴者的心电信号；所述干预输出模块用于控制所述前直流电流发生器和所述后直流电流发生器产生电干预信号、控制所述左磁刺激发生器和所述右磁刺激发生器产生磁干预信号以及控制所述左耳机和所述右耳机产生声干预信号；所述电源管理模块用于对供电电源进行管理；所述传输处理模块用于传输和处理所述心电信号。
可选的，所述传输处理模块为功率放大器。
本发明还提供了一种脑力疲劳干预方法，所述方法用于上述所述的脑力疲劳干预设备；所述方法包括：
获取左心电采集电极和右心电采集电极采集到的佩戴者的心电信号，并将所述心电信号传输至上位机；
接收所述上位机发送的脑疲劳程度信号；
由所述脑疲劳程度信号控制前直流电流发生器和后直流电流发生器产生电干预信号、控制左磁刺激发生器和右磁刺激发生器产生磁干预信号以及控制左耳机和右耳机产生声干预信号。
与现有技术相比，本发明的有益效果是：
本发明提出了一种脑力疲劳干预设备及干预方法，脑力疲劳干预设备包括头箍本体和设置在所述头箍本体上的前直流电流发生器、后直流电流 发生器、左磁刺激发生器、右磁刺激发生器、左心电采集电极、右心电采集电极、左耳机、右耳机和电路板。由心电采集电极获得佩戴者的心电信号；由直流电流发生器产生直流电实现经颅电刺激；由耳机播放音频实现脑疲劳的声音干预；由磁刺激发生器产生弱强度磁刺激实现对脑额叶区和医明(耳后侧)等主要穴位的重复连续磁刺激。本发明同时采用声、电、磁三种物理刺激，实现了复合干预，干预精准度高，从而更稳定、更快速、更大程度的达到了更好的脑力疲劳缓解效果，提高了睡眠质量。
说明书附图
为了更清楚地说明本发明实施例或现有技术中的技术方案，下面将对实施例中所需要使用的附图作简单地介绍，显而易见地，下面描述中的附图仅仅是本发明的一些实施例，对于本领域普通技术人员来讲，在不付出创造性劳动性的前提下，还可以根据这些附图获得其他的附图。
图1为本发明实施例一种脑力疲劳干预设备在一个方向上的结构图；
图2为本发明实施例一种脑力疲劳干预设备在另一个方向上的结构图；
图3为本发明实施例电路板的结构示意图；
图4为本发明实施例采集模块的电路原理图；
图5为本发明实施例干预输出模块中直流电刺激输出干预驱动电路的原理图；
图6为本发明实施例干预输出模块中磁刺激模块的电压电流转换电路的原理图；
图7为本发明实施例电源管理模块的电路原理图；
图8为本发明实施例传输处理模块的电路原理图；
图9为本发明具体实施例中脑力疲劳干预方法的流程图。
具体实施方式
下面将结合本发明实施例中的附图，对本发明实施例中的技术方案进行清楚、完整地描述，显然，所描述的实施例仅仅是本发明一部分实施例，而不是全部的实施例。基于本发明中的实施例，本领域普通技术人员在没 有做出创造性劳动前提下所获得的所有其他实施例，都属于本发明保护的范围。
为使本发明的上述目的、特征和优点能够更加明显易懂，下面结合附图和具体实施方式对本发明作进一步详细的说明。
图1为本发明实施例一种脑力疲劳干预设备在一个方向上的结构图；图2为本发明实施例一种脑力疲劳干预设备在另一个方向上的结构图。
参见图1-图2，本实施例的脑力疲劳干预设备，包括：头箍本体和设置在所述头箍本体上的前直流电流发生器1、后直流电流发生器2、左磁刺激发生器3、右磁刺激发生器4、左心电采集电极5、右心电采集电极6、左耳机7、右耳机8和电路板9。
所述前直流电流发生器1位于前额中部；所述后直流电流发生器2位于脑后；所述左耳机7设置在所述头箍本体的左侧，所述右耳机8设置在所述头箍本体的右侧；所述前直流电流发生器1的左侧设置左磁刺激发生器3，所述前直流电流发生器1的右侧设置右磁刺激发生器4；所述左磁刺激发生器3与所述左耳机7之间设置左心电采集电极5；所述右磁刺激发生器4与所述右耳机8之间设置右心电采集电极6；所述前直流电流发生器1、所述后直流电流发生器2、所述左磁刺激发生器3、所述右磁刺激发生器4、所述左心电采集电极5、所述右心电采集电极6、所述左耳机7、所述右耳机8均与所述电路板9电连接。
作为一种可选的实施方式，所述头箍本体包括前箍体10和连接部11；所述前箍体10为不封闭的环形箍；所述前箍体10的端部通过所述连接部11连接；所述前直流电流发生器1、所述左磁刺激发生器3、所述右磁刺激发生器4、所述左心电采集电极5、所述右心电采集电极6、所述左耳机7和所述右耳机8均设置在所述前箍体10的内侧；所述后直流电流发生器2设置在所述连接部11的内侧；所述电路板9设置在所述连接部11的内部。
作为一种可选的实施方式，所述前直流电流发生器1和所述后直流电流发生器2均为直流电刺激电极。
作为一种可选的实施方式，所述左磁刺激发生器3和所述右磁刺激发生器4均为磁刺激线圈。
作为一种可选的实施方式，所述左心电采集电极5和所述右心电采集电极6均为单导心电电极。
作为一种可选的实施方式，所述头箍本体为便携头戴式箍体。
作为一种可选的实施方式，所述脑力疲劳干预设备，还包括上位机；所述上位机与所述电路板9无线连接。本实施例中，所述上位机与所述电路板9的通讯方式为WiFi无线通讯。所述上位机用于控制声卡以及上位机控制软件。所述上位机控制软件，与声卡一同控制音乐信号的产生，与电路板9一同控制磁刺激发生电路发生磁信号。具体的，所述上位机可以为电脑。
作为一种可选的实施方式，所述上位机控制软件还包括生理数据分析模块，其对接收到的心电采集电极采集到的心电信号综合分析得到佩戴者的节律情况和脑疲劳程度。所述上位机控制软件根据佩戴者的节律情况和脑疲劳程度确定即时、快速的声音干预方法、稳定有效的电刺激干预方案和具有长效改善功能的磁刺激干预方案。
作为一种可选的实施方式，图3为本发明实施例电路板的结构示意图，参见图3，所述电路板9包括采集模块901、干预输出模块902、电源管理模块903和传输处理模块904。其中，采集模块901的电路原理图如图4所示，图4中ELE_RA、ELE_LA、ELE_LL是心电采集的模拟信号输入点，心电信号模拟输入，然后经过U1实现模拟到数字的转换。干预输出模块902包括两部分电路结构，第一部分为直流电刺激输出干预驱动电路，如图5所示，图5中有CLR、LATCH、SCLK、DIN、SDO接收传输处理模块的信息，以改变IOUT电流输出的大小；第二部分为磁刺激模块的电压电流转换电路，如图6所示，图6中电压信号经过R8输入，然后经过U4A、U0A和Q1后输出一定的电流信号，用来驱动磁刺激线圈。电源管理模块903的电路原理图如图7所示，传输处理模块904的电路原理图如图8所示。所述采集模块901用于控制所述左心电采集电极5和所述右心电采集电极6采集佩戴者的心电信号；所述干预输出模块902用于控制所述前直流电流发生器1和所述后直流电流发生器2采用经颅电刺激(transcranial direct current stimulation，tDCS)方式对大脑前额叶皮层进行直流电刺激的方式，产生电干预信号、控制所述左磁刺激发生器3 和所述右磁刺激发生器4采用对前额和医明穴位等部位进行弱强度磁刺激的方式，产生磁干预信号以及控制所述左耳机7和所述右耳机8采用粉红噪音与舒缓曲循环播放的方式产生声干预信号；所述电源管理模块903用于对供电电源进行管理，控制经颅电刺激(tDCS)发生电路发生电信号；所述传输处理模块904用于传输和处理所述心电信号。
作为一种可选的实施方式，所述传输处理模块904为功率放大器。
作为一种可选的实施方式，所述左耳机7和所述右耳机8均为高品质耳机；所述左耳机7设置于所述头箍本体的左侧T型区底部；所述右耳机8设置于所述头箍本体的右侧T型区底部。
本实施的脑力疲劳干预设备，采用磁刺激干预手段的磁刺激发生器对前额和医明穴位等产生弱强度磁刺激；采用电刺激干预手段的直流电流发生器，以经颅电刺激(tDCS)方式对大脑前额叶皮层进行直流电刺激；采用为获得佩戴者生理电信号的心电采集电极采集佩戴者的心电信息；采用声刺激干预手段的耳机循环播放粉红噪音与舒缓曲，这样同时采用声、电、磁三种刺激干预方式实现对佩戴者的脑力疲劳的检测和缓解，实现了复合干预，从而提高了干预精准度，达到了脑力检测脑力疲劳、改善睡眠状态的目的。
本发明还提供了一种脑力疲劳干预方法，所述方法用于上述所述的脑力疲劳干预设备；所述方法包括：
1)获取左心电采集电极5和右心电采集电极6采集到的佩戴者的心电信号，并将所述心电信号传输至上位机。
2)接收所述上位机发送的脑疲劳程度信号。
3)由所述脑疲劳程度信号控制前直流电流发生器1和后直流电流发生器2产生电干预信号、控制左磁刺激发生器3和右磁刺激发生器4产生磁干预信号以及控制左耳机7和右耳机8产生声干预信号。
下面提供了一个更为具体的脑力疲劳干预方法，图9为本发明具体实施例中脑力疲劳干预方法的流程图。
参见图9，左心电采集电极5和右心电采集电极6采集得到佩戴者心电信息后，将所得的心电信号传递给电路板9的采集模块901。
电路板9的传输处理模块904与上位机进行通讯将得到的心电信号传 输给上位机(电脑)；电脑控制上位机软件将得到的心电信号处理分析得到佩戴者的节律情况和脑疲劳程度；上位机软件确定即时、快速的声音干预，稳定有效的电刺激干预和具有长效改善功能的磁刺激干预的综合干预方案；电脑将制定的方案传输给电路板9的传输处理模块904。
电路板9接收到干预方案之后：
一方面，电脑控制声卡发生相应的音乐信号，并由干预输出模块902驱动左耳机7和右耳机8播放方案中设定的循环粉红噪音+舒缓曲。
一方面，上位机控制软件和电源管理模块903控制磁刺激发生电路发生相应的磁刺激信号，经功率放大器放大后由干预输出模块902驱动磁刺激线圈拟在前额、医明等穴位产生磁刺激。
另一方面，电源管理模块903控制tDCS电刺激发生电路发生相应的直流电刺激信号，经功率放大器放大后由干预输出模块902控制直流电刺激电极拟在大脑前额叶皮层进行阴极电刺激，从而实现精准高效干预的目的。
这样三种干预手段同时进行，提高了干预的精准度，达到了缓解佩戴者脑力疲劳、促进睡眠、缓解失眠症状的目的。
本说明书中各个实施例采用递进的方式描述，每个实施例重点说明的都是与其他实施例的不同之处，各个实施例之间相同相似部分互相参见即可。
本文中应用了具体个例对本发明的原理及实施方式进行了阐述，以上实施例的说明只是用于帮助理解本发明的方法及其核心思想；同时，对于本领域的一般技术人员，依据本发明的思想，在具体实施方式及应用范围上均会有改变之处。综上所述，本说明书内容不应理解为对本发明的限制。

Claims (10)

  1. 一种脑力疲劳干预设备，其特征在于，包括：头箍本体和设置在所述头箍本体上的前直流电流发生器、后直流电流发生器、左磁刺激发生器、右磁刺激发生器、左心电采集电极、右心电采集电极、左耳机、右耳机和电路板；
    所述前直流电流发生器位于前额中部；所述后直流电流发生器位于脑后；所述左耳机设置在所述头箍本体的左侧，所述右耳机设置在所述头箍本体的右侧；所述前直流电流发生器的左侧设置左磁刺激发生器，所述前直流电流发生器的右侧设置右磁刺激发生器；所述左磁刺激发生器与所述左耳机之间设置左心电采集电极；所述右磁刺激发生器与所述右耳机之间设置右心电采集电极；所述前直流电流发生器、所述后直流电流发生器、所述左磁刺激发生器、所述右磁刺激发生器、所述左心电采集电极、所述右心电采集电极、所述左耳机、所述右耳机均与所述电路板电连接。
  2. 根据权利要求1所述的一种脑力疲劳干预设备，其特征在于，所述头箍本体包括前箍体和连接部；所述前箍体为不封闭的环形箍；所述前箍体的端部通过所述连接部连接；所述前直流电流发生器、所述左磁刺激发生器、所述右磁刺激发生器、所述左心电采集电极、所述右心电采集电极、所述左耳机和所述右耳机均设置在所述前箍体的内侧；所述后直流电流发生器设置在所述连接部的内侧；所述电路板设置在所述连接部的内部。
  3. 根据权利要求1所述的一种脑力疲劳干预设备，其特征在于，所述前直流电流发生器和所述后直流电流发生器均为直流电刺激电极。
  4. 根据权利要求1所述的一种脑力疲劳干预设备，其特征在于，所述左磁刺激发生器和所述右磁刺激发生器均为磁刺激线圈。
  5. 根据权利要求1所述的一种脑力疲劳干预设备，其特征在于，所述左心电采集电极和所述右心电采集电极均为单导心电电极。
  6. 根据权利要求1所述的一种脑力疲劳干预设备，其特征在于，所述头箍本体为头戴式箍体。
  7. 根据权利要求1所述的一种脑力疲劳干预设备，其特征在于，还包括上位机；所述上位机与所述电路板无线连接。
  8. 根据权利要求1所述的一种脑力疲劳干预设备，其特征在于，所 述电路板包括采集模块、干预输出模块、电源管理模块和传输处理模块；所述采集模块用于控制所述左心电采集电极和所述右心电采集电极采集佩戴者的心电信号；所述干预输出模块用于控制所述前直流电流发生器和所述后直流电流发生器产生电干预信号、控制所述左磁刺激发生器和所述右磁刺激发生器产生磁干预信号以及控制所述左耳机和所述右耳机产生声干预信号；所述电源管理模块用于对供电电源进行管理；所述传输处理模块用于传输和处理所述心电信号。
  9. 根据权利要求8所述的一种脑力疲劳干预设备，其特征在于，所述传输处理模块为功率放大器。
  10. 一种脑力疲劳干预方法，其特征在于，所述方法用于如权利要求1-9中任意一项所述的脑力疲劳干预设备；所述方法包括：
    获取左心电采集电极和右心电采集电极采集到的佩戴者的心电信号，并将所述心电信号传输至上位机；
    接收所述上位机发送的脑疲劳程度信号；
    由所述脑疲劳程度信号控制前直流电流发生器和后直流电流发生器产生电干预信号、控制左磁刺激发生器和右磁刺激发生器产生磁干预信号以及控制左耳机和右耳机产生声干预信号。
PCT/CN2021/073000 2020-06-11 2021-01-21 一种脑力疲劳干预设备及干预方法 WO2021248914A1 (zh)

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