WO2021238415A1 - Appareil d'implant et prothèse visuelle équipée de celui-ci - Google Patents

Appareil d'implant et prothèse visuelle équipée de celui-ci Download PDF

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Publication number
WO2021238415A1
WO2021238415A1 PCT/CN2021/085599 CN2021085599W WO2021238415A1 WO 2021238415 A1 WO2021238415 A1 WO 2021238415A1 CN 2021085599 W CN2021085599 W CN 2021085599W WO 2021238415 A1 WO2021238415 A1 WO 2021238415A1
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WO
WIPO (PCT)
Prior art keywords
hole
annular
electronic device
flexible electrode
stimulation
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Application number
PCT/CN2021/085599
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English (en)
Chinese (zh)
Inventor
戴聿昌
庞长林
Original Assignee
微智医疗器械有限公司
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Publication of WO2021238415A1 publication Critical patent/WO2021238415A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/08—Devices or methods enabling eye-patients to replace direct visual perception by another kind of perception
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/141—Artificial eyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0526—Head electrodes
    • A61N1/0543—Retinal electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36046—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of the eye

Definitions

  • the present disclosure relates to the technical field of implantable medical devices, and in particular to an implantation device and a visual prosthesis having the same.
  • Visual prosthesis is an implantable medical device designed to help patients with diseased retina or other visual organs regain light and vision.
  • the formation of normal vision is that the photoreceptor cells on the retina (such as cones and rod cells) convert light stimulation into electrical signals, which are encoded on the various layers of the retina (such as horizontal cells, bipolar cells, ganglion cells, etc.) After that, the nerve impulse is transmitted to the visual cortex.
  • a commonly used visual prosthesis design is to implant microelectrode implants on the surface of the retina to help patients with outer retinal degeneration diseases such as retinitis pigmentosa and age-related macular degeneration.
  • the visual prosthesis includes two parts: an implant and an external component.
  • the electronic package in the implant is sutured on the outer side of the eyeball sclera, the flexible electrode passes through the eyeball wall, and the electrode array at the end is fixed on the surface of the retina by fixing nails.
  • the external components include a camera that collects video information. After data conversion, the video information collected by the camera is wirelessly transmitted to the electronic package of the implant.
  • the electrode array transmits stimulation to the retina through electrical stimulation, and transmits electrical pulse signals to the retina. Stimulate the functional neurons on the retina, and transmit this stimulus to the brain through the optic nerve, so that the patient can produce visual perception.
  • a loop needs to be formed after electrical stimulation, so that the current returns to the electronic package to form a circuit loop.
  • a common method is to set loop electrodes on the flexible electrodes.
  • This method has a complicated structure, which increases the difficulty of manufacturing the flexible electrodes, and also causes the electrical stimulation circuit to be confined in the vitreous cavity of the eyeball. Since the current does not penetrate deeply into the retinal cells, it will cause the need to apply a larger stimulation current to ensure the stimulation effect.
  • the electrode array needs to bear a greater load, consumes electricity, reduces the battery life, and the patient uses it for a long time. Visual prostheses are prone to fatigue.
  • an objective of the present disclosure is to provide an implantation device, which has a simple structure and is easy to manufacture.
  • Another object of the present disclosure is to provide a visual prosthesis with the above-mentioned implant device.
  • An implant device includes: a housing, the housing including a ring-shaped housing and a cover that closes the ring-shaped housing, the ring-shaped housing is a metal housing; a flexible electrode, the The flexible electrode includes a lead-in part, a cable, and a stimulation part, the cable is connected between the lead-in part and the stimulation part; an electronic device, the electronic device is connected to the lead-in part and forms an electronic device package, the The electronic device package is located in the space formed by the annular housing and the cover, the introduction part of the flexible electrode is electrically connected to the inner wall of the annular housing, and the implantation device is driven by a forward voltage
  • the current drive output port in the electronic device package, the introduction portion of the flexible electrode, the stimulation portion, the stimulated tissue, the annular housing, and the current drive in the electronic device package are formed sequentially. Electrical stimulation circuit of circuit ground.
  • the electronic device package formed by the lead-in part of the electronic device and the flexible electrode is arranged in the housing, and the lead-in part is electrically connected to the ring-shaped housing through the ring-shaped housing itself.
  • the electrical conductivity of the device can form an electrical stimulation loop, so there is no need to set loop electrodes, and the entire implant device has a simple structure and is easy to process and manufacture.
  • a connecting hole is formed on the introduction part of the flexible electrode, a connecting post is provided in the annular housing, and the connecting hole is electrically connected to the connecting post.
  • connection hole and the connection post are connected by conductive glue.
  • the flexible electrode is formed with a connecting piece extending outward from the introduction part of the flexible electrode, the connecting hole is formed on the connecting piece, and the connecting piece
  • the side wall of the hole is formed with at least one slit hole that is recessed toward a direction away from the center of the connecting hole.
  • the number of the slit holes is multiple, each of the slit holes extends along the radial direction of the connecting hole, and the plurality of slit holes are uniform along the circumferential direction of the connecting hole Interval distribution.
  • the slit hole is a straight hole, a curved hole or a broken line hole.
  • an extension portion extending inwardly is provided on the inner wall of the annular housing, wherein the connecting column is connected to an end of the extension portion.
  • the electronic device package further includes a coil
  • the top and bottom of the ring-shaped casing are both open
  • the cover includes an upper cover and a lower cover
  • the upper cover is arranged on the ring
  • the lower cover is arranged at the bottom of the annular casing, and a slit is formed on the annular casing.
  • the upper cover and the lower cover respectively enclose the top and the bottom of the annular housing, and the upper cover is formed to be concave toward a direction away from the lower cover A curved shape, and the lower cover is formed into a curved shape that is concave toward the upper cover.
  • the material of the annular shell is pure titanium, titanium alloy, platinum, platinum alloy or platinum-iridium alloy
  • the upper cover and the lower cover are ceramic parts, glass parts or polymer parts.
  • a threaded hole is formed on the annular housing, the flexible electrode passes through the threaded hole, the slit and the threaded hole communicate with each other, and the slit It is in an inverted T shape together with the wire passing hole.
  • the space between the housing and the electronic device package is filled with sealant.
  • At least one sewing hook is provided on the outer wall of the annular housing, and the at least one sewing hook is only arranged on one side of the annular housing.
  • the sewing hook includes a connecting part connected to the annular housing and a hook part connected to a free end of the connecting part.
  • the hook part adopts a non-closed loop structure.
  • a visual prosthesis according to an embodiment of the second aspect of the present disclosure includes: an implantation device, the implantation device being the implantation device according to the embodiment of the first aspect of the present disclosure, the implantation device is used to implant the brain Or the eye; an external device, the external device includes: a camera unit, a video processing unit and a wireless signal device, the camera unit is electrically connected to the video processing unit, the video processing unit and the wireless signal device are electrically connected , The wireless annunciator and the implanted device are connected for energy and data in a wireless coupling manner.
  • Figure 1 is an exploded view of an implant device according to an embodiment of the present disclosure
  • Fig. 2 is a schematic diagram of the implantation device shown in Fig. 1 after being assembled;
  • Figure 3 is a perspective view of the annular housing shown in Figure 1;
  • Fig. 4 is a top view of the annular housing and flexible electrode shown in Fig. 1;
  • FIG. 5 is a schematic diagram of the flexible electrode shown in FIG. 4;
  • Fig. 6 is an enlarged view of part A circled in Fig. 5;
  • Fig. 7 is a schematic diagram of the implantation device according to an embodiment of the present disclosure when the eyeball is implanted;
  • FIG. 8 is a schematic diagram of the implantation device according to an embodiment of the present disclosure when it is implanted into the cerebral cortex;
  • Fig. 9 is a schematic diagram of a visual prosthesis according to an embodiment of the present disclosure.
  • 100 implant device; 1: housing; 11: annular shell; 111: connecting column; 112: extension; 113: slit;
  • 22 stimulation part; 23: cable; 3: electronic device package; 31: coil; 200: external device;
  • 210 camera unit
  • 220 video processing unit
  • 230 wireless signal device
  • 1000 eyeball
  • 1001 retina
  • the implantation device 100 according to an embodiment of the first aspect of the present disclosure will be described below with reference to FIGS. 1 to 8.
  • the implant device 100 can be suitable for implanting in the human body such as cochlear implants, retinal implants, spinal cord stimulators (for the treatment of pain), cerebral cortex stimulators, deep brain stimulators (brain pacemakers), etc.
  • the implantation device 100 and the retinal implant for cerebral cortex stimulation visual prosthesis are mainly described as examples.
  • the implantation device 100 includes a housing 1, a flexible electrode 2, and an electronic device.
  • the housing 1 includes a ring-shaped housing 11 and a cover that closes the ring-shaped housing 11.
  • the body encloses the open part of the annular casing 11 (for example, the top and bottom in FIGS. 1 and 3) to jointly define the accommodating cavity with the annular casing 11.
  • the annular shell 11 is a metal shell.
  • the annular housing 11 is made of a metal material so as to form an electrical connection with the lead-in portion 21 of the flexible electrode 2.
  • the flexible electrode 2 includes an introduction part 21, a stimulation part 22 and a cable 23, and the cable 23 is connected between the introduction part 21 and the stimulation part 22.
  • the stimulation part 22 may include a flexible substrate and a plurality of stimulation electrodes provided on the flexible substrate.
  • the flexible substrate may support and protect the stimulation electrodes, and the ends of the plurality of stimulation electrodes may be exposed to one part of the flexible substrate.
  • the side surface is suitable for stimulating the implanted part of the human body (for example, the retina 1001, the cerebral cortex 3000, etc.).
  • a plurality of stimulation electrodes may be arranged in the flexible substrate in an array manner (for example, in rows and columns).
  • the electronic device is connected to the lead-in portion 21 of the flexible electrode 2 and forms an electronic device package 3.
  • the electronic device may include a circuit chip, such as an ASIC (Application Specific Integrated Circuit, application specific integrated circuit) chip.
  • the circuit chip is used to process received data signals and send out electrical stimulation pulses for driving stimulation electrodes.
  • Electronic devices may also include capacitors, inductors, resistors, oscillators, filters, memories, and other electronic components that may be provided according to the circuit design.
  • the electronic device package 3 is located in the space formed by the annular casing 11 and the cover (that is, the above-mentioned accommodating cavity).
  • the lead-in part 21 of the flexible electrode 2 is electrically connected to the inner wall of the annular housing 11.
  • the implant device 100 is driven by a forward voltage
  • the current-driven output port and the lead-in part 21 of the flexible electrode 2 in the electronic device package 3 are sequentially formed.
  • the implant device 100 is driven by a reverse voltage, the direction of the current is opposite to the direction of the aforementioned electrical stimulation circuit, which will not be repeated here.
  • the electrical stimulation process driven by the forward voltage may be specifically as follows: After the electronic device package 3 in the housing 1 receives the external radio frequency signal, it sends multiple stimuli to the stimulation part 22 The electrodes send electrical pulse signals, and multiple stimulation electrodes apply current stimulation to the surface of the retina 1001 to help the patient obtain visual perception. At the same time, the current flows in the direction of low potential, that is, flows through the eyeball wall to the ring housing 11 fixed on the sclera. At the bottom end, since the lead-in portion 21 of the flexible electrode 2 is electrically connected to the inner wall of the annular casing 11, it can further flow to the electronic device package 3.
  • a circuit loop can be formed without providing a special loop electrode, with fewer parts, simple structure, and easy processing and manufacturing.
  • the stimulation current passes through the eyeball wall and can penetrate deeply into the retinal cells, compared with the traditional way of setting loop electrodes on flexible electrodes, it only needs to provide a smaller current intensity to achieve the same stimulation effect, which can extend the battery.
  • the use time of the flexible electrode 2 saves electric energy, and the stimulation electrode on the stimulation part 22 only needs to bear a small load, which prolongs the service life of the flexible electrode 2.
  • a connecting hole 2111 is formed on the lead-in portion 21 of the flexible electrode 2, a connecting post 111 and a connecting hole 2111 are provided in the annular housing 11 It is electrically connected to the connecting pole 111.
  • the connecting column 111 may be integrally formed inside the annular housing 11, and the connecting column 111 may extend along the axial direction of the annular housing 11, and the connecting hole 2111 may extend along the thickness direction of the introduction portion 21. The lead-in portion 21 of the flexible electrode 2 is penetrated.
  • connection hole 2111 of the introduction part 21 and the connection post 111 are connected by conductive glue.
  • the conductive glue is easily adhered between the side wall of the connecting hole 2111 and the outer peripheral wall of the connecting pillar 111, and after curing, the reliability of the electrical connection between the introduction part 21 and the annular casing 11 is further improved.
  • the flexible electrode 2 is formed with a connecting piece 211, the connecting piece 211 extends outward from the introduction part 21, and the connecting hole 2111 is formed on the connecting piece 211.
  • the connecting piece 211 is arranged at the edge of the introduction part 21, one end of the connecting piece 211 is connected to the edge of the introduction part 21, and the other end of the connecting piece 211 is connected to the surface of the introduction part 21. Spaced apart, it is convenient to arrange electronic devices and reduce the overall size.
  • the side wall of the connecting hole 2111 is formed with at least one slit hole 2112 that is recessed toward a direction away from the center of the connecting hole 2111.
  • the slit hole 2112 penetrates the connecting piece 211 along the thickness direction of the connecting piece 211, and one end of the slit hole 2112 is in communication with the connecting hole 2111.
  • stress concentration can be prevented, and the conductive glue can also enter the slit hole 2112, thereby further improving the reliability of the electrical connection between the connecting pillar 111 and the connecting hole 2111.
  • the connecting post 111 and the connecting hole 2111 can be interference fit or transition fit.
  • the number of the slit holes 2112 is multiple, and each slit hole 2112 extends along the radial direction of the connecting hole 2111, and the multiple slit holes 2112 are evenly spaced along the circumferential direction of the connecting hole 2111. The included angles between every two adjacent slit holes 2112 are equal.
  • the slit hole 2112 provided in this way allows the connecting hole 2111 to produce greater deformation, and the force of the connecting hole 2111 can be more uniform.
  • "plurality" means two or more.
  • the slit hole 2112 may be a curved hole (such as an arc-shaped hole, a wave-shaped hole, etc.), a broken line hole (such as a W-shaped hole, etc.), in addition to the linear hole shown in FIG. 6.
  • the inner wall of the annular housing 11 is provided with an extension portion 112 extending inwardly, wherein the connecting post 111 is connected to an end portion of the extension portion 112 (for example, Inner end in Figure 3).
  • the lower end of the connecting post 111 is connected to the inner end of the extension portion 112 and extends upward, so that the connecting post 111 can pass through the connecting hole 2111 on the introduction part 21 during the process of putting the electronic device package 3 into the annular housing 11 , Thereby improving assembly efficiency.
  • the electronic device package 3 further includes a coil 31, the top and bottom of the annular housing 11 are both open, and the cover includes an upper cover 12 and a lower cover 13.
  • the upper cover 12 is arranged on the top of the annular casing 11
  • the lower cover 13 is arranged on the bottom of the annular casing 11, and a slit 113 is formed on the annular casing 11.
  • the slit 113 will not hinder the signal communication, can avoid the eddy current of the coil 31, and ensure the stable and reliable transmission of the radio frequency signal of the coil 31.
  • the implant device 100 when the implant device 100 is implanted in the eyeball 1000, even if the eyeball 1000 moves or the distance between the external coil (not shown) and the electronic device package 3 is large, stable and reliable signal transmission can still be ensured. It should be noted that if the coil 31 is not placed in the annular casing 11, the annular casing 11 may not be provided with a slit.
  • the upper cover 12 and the lower cover 13 respectively close the top and bottom of the annular housing 11, and the upper cover 12 may be formed as a curved surface that is concave toward the direction away from the lower cover 13.
  • the lower cover 13 may be formed into a curved shape that is concave toward the upper cover 12. Therefore, when the implant device 100 is implanted in the eyeball 1000, since the lower cover 13 is configured as a curved surface that matches the sclera, it can better fit the sclera, and because the upper cover 12 also has a corresponding curved structure, and Located between the eyelid and sclera, it can reduce the patient's foreign body sensation.
  • the material of the annular shell 11 is pure titanium, titanium alloy, platinum, platinum alloy, platinum iridium alloy and other metals
  • the upper cover 12 and the lower cover 13 are ceramic parts, glass parts or polymers (such as polyether ether ketone). Etc.), but not limited to this.
  • the coil 31 is used to receive data and energy, and the number of the coil 31 can be one or more.
  • the coil 31 may include an internal data coil and an internal energy coil for receiving data and energy from the external coil, respectively.
  • a via 115 is formed on the annular housing 11, the flexible electrode 2 can pass through the via 115, the slit 113 and the via 115 are in communication with each other, and The slit 113 and the threading hole 115 are in an inverted T shape.
  • the inverted T-shaped hole penetrates the top and bottom of the annular shell 11, so that the eddy current of the coil 31 is effectively avoided, and the flexible electrode 2 can pass through the thread.
  • the hole 115 protrudes to the outside of the housing 1.
  • the slit 113 can also penetrate through the top and bottom of the annular casing 11 and be circumferentially spaced from the thread-passing hole 115 (not shown in the figure).
  • At least one sewing hook 114 is provided on the outer wall of the annular housing 11, and the at least one sewing hook 114 is only arranged on one side of the annular housing 11.
  • two suture hooks 114 are shown.
  • the housing 1 can be firmly sutured to the tissue to be sutured (such as sclera) by means of suture hooks 114, and the side of the annular shell 11 that does not have the suture hooks 114 (for example, the upper side in FIG.
  • each sewing hook 114 may include a connecting portion 1141 connected to the annular housing 11 and a hook portion 1142 connected to a free end of the connecting portion 1141. Since the hook portion 1142 adopts a non-closed loop structure, the eddy current of the coil 31 can be further avoided.
  • the space between the housing 1 and the electronic device package 3 is filled with sealant, which can further ensure the sealing and corrosion resistance of the implant device 100.
  • the sealant can be filled into the space between the housing 1 and the electronic device package 3 through the slit 113.
  • the sealant is silica gel or epoxy glue, but it is not limited thereto.
  • a cable 23 is connected between the introduction part 21 and the stimulation part 22 of the flexible electrode 2.
  • the cable 23 can pass through the wire hole 115 to extend out of the housing 1.
  • the size of the implant device 100 can be significantly reduced.
  • the part of the implant device 100 located outside the eye only needs to cover one quadrant of the sclera ( Generally, the upper temporal quadrant) can be implanted.
  • the annular shell 11 is sutured to the supratemporal quadrant of the sclera, and the distance between the suture hook 114 and the limbus is ensured. Then vitrectomy is performed, and the sclera is cut in the superior temporal quadrant to form an incision.
  • the stimulation part 22 of the flexible electrode 2 is introduced into the eyeball 1000 from the incision, and the stimulation part 22 is fixed to the macular area on the surface of the retina 1001 by a fixing nail 2000.
  • the implantation operation is simple, has little trauma to the eyes, avoids compression of the ocular vortex vein, has fewer postoperative complications, and can reduce the patient's foreign body sensation.
  • the stimulation part 22 is implanted on the surface of the cerebral cortex 3000, and the shell 1 is implanted in the hollow part of the skull, or on the skull or under the scalp.
  • the stimulation part 22 with stimulation electrodes can be implanted in the V1 area of the visual cortex of the brain, and can also partially cover the V2 or V3 area. It is worth noting that the V1, V2, and V3 areas of the visual cortex of the brain mentioned here are common areas in the visual field of the brain, and will not be explained in detail here.
  • the visual prosthesis according to the embodiment of the second aspect of the present disclosure includes an implant device 100 and an external device 200.
  • the implant device 100 is the implant device 100 according to the embodiment of the first aspect of the present disclosure.
  • the implant device 100 is used to implant the brain or the eye.
  • the stimulation portion 22 of the flexible electrode 2 can be used to treat the visual cortex or retinal cells. Perform stimulation.
  • the external device 200 includes a camera unit 210, a video processing unit 220, and a wireless annunciator 230.
  • the camera unit 210 is electrically connected to the video processing unit 220
  • the video processing unit 220 is electrically connected to the wireless annunciator 230
  • the wireless annunciator 230 is connected to the implant device 100.
  • the energy and data connection is performed through a wireless coupling, for example, an external coil is used to perform wireless transmission of data and energy with the coil 31 in the implant device 100.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
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  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Prostheses (AREA)
  • Electrotherapy Devices (AREA)

Abstract

L'invention porte sur un appareil d'implant (100) et une prothèse visuelle équipée de celui-ci. L'appareil d'implant (100) comprend une coque externe (1), une électrode flexible (2) et un dispositif électronique. La coque externe (1) comprend une coque annulaire (11), et un couvercle qui renferme la coque annulaire (11), la coque annulaire (11) étant une coque métallique. L'électrode flexible (2) comprend une partie d'entrée (21), un câble (23) et une partie de stimulation (22), le câble (23) étant connecté entre la partie d'entrée (21) et la partie de stimulation (22). Le dispositif électronique est relié à la partie d'entrée (21) pour former un boîtier de dispositif électronique (3), le boîtier de dispositif électronique (3) est situé dans un espace formé par la coque annulaire (11) et le couvercle, et la partie d'entrée (21) est électriquement connectée à une paroi interne de la coque annulaire (11). Lorsqu'il est entraîné par une tension directe, l'appareil d'implant (100) forme une boucle de stimulation électrique qui circule de manière séquentielle à partir d'un port de sortie de commande de courant dans le boîtier de dispositif électronique (3), en passant par la partie d'entrée (21), la partie de stimulation (22), un tissu stimulé et la coque annulaire (11), pour aller jusqu'à un fil de masse de circuit de commande de courant dans le boîtier de dispositif électronique (3).
PCT/CN2021/085599 2020-05-27 2021-04-06 Appareil d'implant et prothèse visuelle équipée de celui-ci WO2021238415A1 (fr)

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CN202010459954.4A CN111481344A (zh) 2020-05-27 2020-05-27 植入装置和具有其的视觉假体
CN202010459954.4 2020-05-27

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Families Citing this family (5)

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Publication number Priority date Publication date Assignee Title
CN111481344A (zh) * 2020-05-27 2020-08-04 微智医疗器械有限公司 植入装置和具有其的视觉假体
CN111588985B (zh) * 2020-05-27 2021-02-19 微智医疗器械有限公司 植入装置及其组装方法
CN111588984B (zh) * 2020-05-27 2021-02-19 微智医疗器械有限公司 植入式视网膜电刺激器及其植入体
CN112451856B (zh) * 2020-12-10 2021-10-01 微智医疗器械有限公司 柔性电极、植入装置和植入式视网膜电刺激器
CN112716689B (zh) * 2020-12-14 2023-09-15 微智医疗器械有限公司 眼科手术器械

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