WO2021223187A1 - 实验动物笼具和实验动物转移装置 - Google Patents

实验动物笼具和实验动物转移装置 Download PDF

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Publication number
WO2021223187A1
WO2021223187A1 PCT/CN2020/089064 CN2020089064W WO2021223187A1 WO 2021223187 A1 WO2021223187 A1 WO 2021223187A1 CN 2020089064 W CN2020089064 W CN 2020089064W WO 2021223187 A1 WO2021223187 A1 WO 2021223187A1
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Prior art keywords
side wall
wall
sub
cage
experimental animal
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PCT/CN2020/089064
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English (en)
French (fr)
Inventor
杨星
刘清晴
王立平
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中国科学院深圳先进技术研究院
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Priority to PCT/CN2020/089064 priority Critical patent/WO2021223187A1/zh
Publication of WO2021223187A1 publication Critical patent/WO2021223187A1/zh

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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K1/00—Housing animals; Equipment therefor
    • A01K1/02—Pigsties; Dog-kennels; Rabbit-hutches or the like
    • A01K1/03—Housing for domestic or laboratory animals

Definitions

  • This application relates to the technical field of laboratory animal feeding devices, in particular to animal testing cages and experimental animal transfer devices.
  • the non-human primate model is widely used to study the pathology and treatment of emotions, cognition, social interaction, and various diseases, such as addiction, depression, and heart disease.
  • Vascular disease, cancer, AIDS, multiple sclerosis, organ transplantation, etc. In fact, as the last step before clinical trials, new drug treatments will definitely be tested for safety and efficacy on non-human primates.
  • the main technical problem solved by this application is to provide an experimental animal cage, which can change the size in a set direction, so as to meet the living space requirements of the experimental animal while facilitating the transfer and transportation of the cage.
  • the experimental animal cage includes a bottom wall, a top wall, and a side wall connecting the bottom wall and the top wall. Foldable; when the side walls are in the unfolded state, the bottom wall, the top wall and the side walls are surrounded to form a first cage shape.
  • the cage In the first cage shape, the cage has a first size in the set direction; on the side When the walls are in the folded state, the bottom wall, the top wall and the side walls are folded to form a second cage shape.
  • the cage In the second cage shape, the cage has a second size in a set direction, and the second size is smaller than the first size.
  • the side wall includes a first side wall and a second side wall that are connected to each other, and the first side wall is connected to the top wall, and the second side wall is connected to the bottom wall; the first side wall can be folded relative to the second side wall .
  • the first side wall includes a plurality of first sub-side walls
  • the second side wall includes a plurality of second sub-side walls
  • the plurality of first sub-side walls and the plurality of second sub-side walls are connected in a one-to-one correspondence.
  • each first sub-side wall is detachably connected to the adjacent first sub-side wall; the top wall is detachably connected to a plurality of first sub-side walls, or the top wall is only connected to one of the first sub-sides
  • the walls are fixedly connected and detachably connected to the first sub-side wall; each first sub-side wall can rotate around the top edge of the corresponding second sub-side wall, so that the first side wall can pass through each first sub-side wall. The rotation of one side wall is folded relative to the second side wall.
  • first side wall and the second side wall are slidably connected, so that one of the first sub-side walls of the first side wall can move to the position of the opposite first sub-side wall; and one of the first sub-side walls
  • the side wall can rotate around the top edge of the second sub-side wall corresponding to the other first sub-side wall, so that the first side wall can be folded relative to the second side wall through the rotation of one of the first sub-side walls.
  • one of the first sub-side walls can be rotated around the top edge of the corresponding second sub-side wall, and the remaining first sub-side walls are detachably connected to the corresponding second sub-side wall, so that the first side wall can pass through it.
  • the rotation of a first side wall is folded relative to the second side wall.
  • the side wall includes a first side wall and a second side wall connected to each other, and the first side wall is connected with the top wall, and the second side wall is connected with the bottom wall; the first side wall can be folded.
  • the first side wall includes a plurality of uprights and a grid structure capable of stretching along the upright; when the first sidewall is stretched along the upright, the cage has a first size in the set direction, and when the first sidewall is extended along the upright When compressed, the cage has a second dimension in the set direction.
  • the set direction is the vertical direction
  • the first size is greater than or equal to 2.5 meters
  • the second size is less than or equal to 2 meters.
  • the cage also includes a plurality of support columns; the side walls are provided with a plurality of fixing holes, the support columns can pass through the fixing holes to extend into the inside of the cage, and the support columns are detachably connected with the side walls.
  • the material of the support column is selected from at least one of wood, plastic, rubber and straw products.
  • the first cage further includes a first moving wall, and a number of sitting stools are arranged on the first moving wall;
  • the side wall includes a plurality of sub-side walls, and the first moving wall can move between two opposite sub-side walls.
  • the first cage body also includes a second moving wall, the second moving wall is provided with a number of through holes, and the through holes correspond to the stool one by one, so that the stool can pass through the through holes; Between the wall and the sub-side wall opposite to the first moving wall.
  • first moving wall and the second moving wall are both foldable structures; when the first side wall or the second moving wall is unfolded in a set direction, the first moving wall and the second moving wall have a set direction The first size; when the first side wall or the second moving wall is folded along the set direction, the first moving wall and the second moving wall have the second size in the set direction.
  • the side wall of the second moving wall facing away from the first moving wall is provided with a first access door; the side of the second moving wall facing away from the first moving wall is provided with a food box and a water bottle rack.
  • the bottom wall is provided with a collection tank, and the collection tank is used to install a collection tray to collect animal excrement.
  • the experimental animal transfer device includes a lifting platform, a transfer cage, and the experimental animal cage according to claim 1;
  • the side wall is provided with a first entry and exit door
  • the side wall of the transfer cage is provided with a second entry and exit door
  • the lifting platform is used for transporting the transfer cage so that the second entry and exit door can be docked with the first entry and exit door.
  • an experimental animal transfer device which includes a lifting platform, a transfer cage, and the above-mentioned experimental animal cage; wherein, the side wall The upper opening is provided with a first entry and exit door, and one side of the transfer cage is opened on the second entry and exit door; the lifting platform is used for transporting the transfer cage so that the second entry and exit door can be docked with the first entry and exit door.
  • the experimental animal cage includes a bottom wall, a top wall, and a side wall connecting the bottom wall and the top wall, and the side wall is foldable, so that when the side wall is in the unfolded state, the bottom wall, top wall and The side walls are surrounded to form a first cage shape.
  • the cage In the first cage shape, the cage has a first size in a set direction to expand the living space of experimental animals; when the side walls are in a folded state, the bottom wall and the top The walls and side walls are folded to form a second cage shape.
  • the cage has a second size in the set direction, and the second size is smaller than the first size to facilitate the transfer and handling of the cage.
  • the applied experimental animal cage can change its size in a set direction through the folding of the side walls, so as to meet the living space requirements of the experimental animal while facilitating the transfer and transportation of the cage.
  • Fig. 1 is a schematic diagram of the first cage morphology of an embodiment of the experimental animal cage of the present application
  • FIG. 2 is a schematic diagram of the second cage shape of an embodiment of the experimental animal cage of the present application.
  • Fig. 3 is a schematic structural diagram of another embodiment of the experimental animal cage of the present application.
  • FIG. 4 is a schematic structural diagram of another embodiment of the experimental animal cage of the present application.
  • Fig. 5 is a schematic structural diagram of another embodiment of the experimental animal cage of the present application.
  • Fig. 6 is a schematic front view of an embodiment of the experimental animal cage of the present application.
  • Fig. 7 is a partial structural diagram of an embodiment of the experimental animal cage of the present application.
  • Fig. 8 is a schematic structural diagram of an embodiment of the experimental animal transfer device of the present application.
  • FIG. 1 is a schematic diagram of the first cage morphology of an embodiment of the experimental animal cage of the present application
  • FIG. 2 is a schematic diagram of the second cage morphology of an embodiment of the experimental animal cage of the present application .
  • the experimental animal cage 100 includes a bottom wall, a top wall 10, and a side wall 20 connecting the bottom wall and the top wall 10, and the side wall 20 is foldable.
  • the bottom wall (not shown), the top wall 10 and the side wall 20 are enclosed to form a first cage form.
  • the cage 100 has a first cage in the set direction One size.
  • the bottom wall, the top wall 10 and the side wall 20 are folded to form a second cage shape.
  • the cage 100 has a second size in the set direction, and the second size Less than the first size.
  • the set direction can be a vertical direction to adjust the height of the cage 100, which is beneficial to meet the needs of some types of experimental animals for vertical living space, for example, to meet the climbing requirements of non-human primates. Habits; it can also be the horizontal direction to adjust the horizontal length of the cage 100, which is conducive to meeting the needs of some types of experimental animals for horizontal living space, for example, it is conducive to meeting the habit of rodents that need to crawl in horizontal living spaces .
  • the specific values of the setting direction and the first size can be determined according to the living habits of the animals to be caged in actual preparations and the height of the laboratory room.
  • the specific value of the second size can be determined according to the restrictions that may be encountered during the transfer of the cage 100, such as the height or width of the transport vehicle, the height or width of the door frame of the laboratory, and so on.
  • the cage 100 may have a cubic shape in the first cage form.
  • it can also be in other shapes, such as a combination of a cubic shape and a spherical shape, and the present embodiment is not limited herein.
  • the experimental animal cage 100 includes a bottom wall, a top wall 10, and a side wall 20 connecting the bottom wall and the top wall 10, and the side wall 20 is foldable, so that when the side wall 20 is in an unfolded state , The bottom wall, the top wall 10 and the side walls 20 are enclosed to form a first cage form.
  • the cage 100 has a first size in a set direction to expand the living space of experimental animals;
  • the bottom wall, the top wall 10 and the side walls 20 are folded to form a second cage shape.
  • the cage 100 has a second size in the set direction, and the second size is smaller than the second size.
  • the experimental animal cage 100 of the present application can change its size in a set direction by folding the side walls 20, so as to meet the living space requirements of the experimental animals. At the same time, it is convenient to transfer and carry the cage 100.
  • the experimental animal cage 100 of this embodiment can be used for cages of non-human primates.
  • non-human primates are generally kept in cages, so sufficient cage space is one of the key elements of the welfare of non-human primates.
  • Many countries and organizations in the world have formulated spatial standards for raising non-human primates. Take a single 3.5 kg macaque as an example.
  • Animal Welfare Act Regulations (AWAR) and The Guide to the Care and Use of Laboratory or Agricultural Animals Animals or its agricultural counterpart) stipulates that the floor space it occupies shall not be less than 0.4 square meters, and the height shall not be less than 0.76 square meters.
  • the height of the cage 100 is more critical, which is related to their arboreal nature Unanimous. When frightened, they tend to climb to high places to avoid danger. If there is not enough space, especially height to avoid threats, or the cage environment is too monotonous, non-human primates will often exhibit stereotyped behaviors such as over-grooming and circling in place, which means that their animal welfare has not been obtained. It is guaranteed that the data collected on them is also unreliable.
  • the current conventional door is generally 2.1 meters high, the cage 100 that exceeds this height is difficult to transfer across the room. In addition, the excessively high cage 100 will also increase the difficulty of operation. These factors limit the height of the cage 100. Amplification.
  • the setting direction can be the vertical direction
  • the first size can be greater than or equal to 2.5 meters, such as 2.5 meters, 3 meters, 3.5 meters, 4 meters or higher, to extend the height of the cage 100 to meet the requirements of non- The climbing nature of human primates and the curiosity to explore new environments
  • the second size can be less than or equal to 2 meters, such as 2 meters, 1.8 meters, 1.5 meters or lower, to reduce the height of the cage 100, which is convenient for the cage 100 transfers through the door.
  • the cage 100 may be cubic in the first cage shape, and the area of the bottom wall is not less than 1 square meter, for example, the length and width of the bottom wall are each greater than 1 meter.
  • the side wall 20 includes a first side wall 21 and a second side wall 22 that are connected to each other, and the first side wall 21 is connected to the top wall 10 and the second side wall 22 is connected to the bottom wall.
  • the side wall 20 may be foldable: the first side wall 21 can be folded relative to the second side wall 22.
  • the first side wall 21 may include a plurality of first sub-side walls 211
  • the second side wall 22 may include a plurality of second sub-side walls 221, the bottom side of the plurality of first sub-side walls 211 and a plurality of The top edges of the second sub-side walls 221 are connected in a one-to-one correspondence.
  • the bottom edge of each first sub-sidewall 211 corresponds to the second The top edges of the sub-side walls 221 are in contact with each other.
  • the first side wall 21 may include four first sub-side walls 211
  • the second side wall 22 may include four second sub-side walls 221.
  • the bottom edge of each first sub-side wall 211 is in contact with the top edge of the corresponding second sub-side wall 221 to form the cage 100.
  • the first sub-side wall 211 and the corresponding second sub-side wall 221 may be connected by a snap connection or connected by a connector provided on the first sub-side wall 211 and the second sub-side wall 221.
  • the plurality of first sub-side walls 211 and the bottom wall, and the plurality of first sub-side walls 211 may be movably connected to each other, so that the plurality of first sub-side walls 211 can be relative to the cage.
  • the body of 100 is opened and closed. After the multiple cages 100 are connected by fixing structures such as buckles provided on the edges, the adjacent first sub-side walls 211 between the multiple cages 100 can be opened to make the multiple cages 100 The space between 100 is connected, thereby further expanding the space in the cage 100.
  • first side wall 21 can be folded relative to the second side wall 22 as follows:
  • Each first sub-side wall 211 is detachably connected to the adjacent first sub-side wall 211.
  • Each first sub-side wall 211 is detachably connected to the adjacent first sub-side wall 211 means that the plurality of first sub-side walls 211 can be detachably connected, for example, among the plurality of first sub-side walls 211 Connected by a snap connection or a pin connection, etc.
  • the top wall 10 is detachably connected to the plurality of first sub-side walls 211, or the top wall 10 is fixedly connected to only one of the first sub-side walls 211, and is detachably connected to the first sub-side wall 211.
  • the top wall 10 and the first sub-side wall 211 are detachably connected, for example, the top wall 10 and the first sub-side wall 211 are connected by a buckle or a pin.
  • Each first sub-side wall 211 can be rotated around the top edge of the corresponding second sub-side wall 221, so that the first side wall 21 can be relative to the second side wall by the rotation of each first sub-side wall 211 22 is folded.
  • Each first sub-side wall 211 can rotate around the top edge of the corresponding second sub-side wall 221, and each first sub-side wall 211 and its corresponding second sub-side wall 221 can be connected by a rotatable connection. Pieces are connected, for example by hinges.
  • the top wall 10 can be fixedly connected with a first sub-side wall 211, and the top wall 10 can be connected to other first sub-side walls. 211 is separated, and the plurality of first sub-side walls 211 are also separated, so that the first sub-side wall 211 rotates around the top edge of the corresponding second sub-side wall 221, so as to reduce the first sub-side wall 211 and the corresponding The included angle between the second sub-side walls 221 can be folded, thereby reducing the size of the cage 100 in the set direction.
  • FIG. 3 is a schematic structural diagram of another embodiment of the experimental animal cage of the present application.
  • first side wall 21 can be folded relative to the second side wall 22 may be:
  • the first side wall 21 and the second side wall 22 are slidably connected, so that one of the first sub-side walls 211 of the first side wall 21 can be moved to the position of the other first sub-side wall 211 opposite thereto.
  • one of the first sub-side walls 211 can rotate around the top edge of the second sub-side wall 221 corresponding to the other first sub-side wall 211, so that the first side wall 21 can pass through one of the first sub-side walls 211 The rotation is folded relative to the second side wall 22.
  • first side wall 21 and the second side wall 22 can be fixed by a detachable connector to form a first cage shape; as shown in Figure 3, when the first side When the wall 21 is in the second state, the first side wall 21 is relatively separated from the second side wall 22 and one of the first sub-side walls 211 of the first side wall 21 is moved to the opposite first sub-side wall 211 The position enables one of the first sub-side walls 211 to rotate around the top edge of the second sub-side wall 221 corresponding to the other first sub-side wall 211.
  • the arrow in FIG. The second cage shape.
  • the first side wall 21 is slidably connected to the second side wall 22, and the bottom side of the first side wall 21 and the top side of the second side wall 22 are connected by a sliding rail 30, so that the first side wall 21 can pass through the sliding rail 30 slides relative to the second side wall 22.
  • the first side wall 21 can be slid as a whole from one end of the second side wall 22 to the other end of the second side wall 22, that is, one of the first sub-side walls 211 can interact with the other corresponding first sub-side wall 211 s position.
  • one of the first sub-side walls 211 can be rotated around the top edge of the second sub-side wall 221 corresponding to the other first sub-side wall 211, so that the first side wall 21 can be integrally relative to the second side wall 22. Folding is performed to reduce the size of the cage 100 in the set direction.
  • FIG. 4 is a schematic structural diagram of another embodiment of the experimental animal cage of the present application.
  • one of the first sub-side walls 211 can rotate around the top edge of the corresponding second sub-side wall 221, and the remaining first sub-side walls 211 are detachably connected to the corresponding second sub-side wall 221. In this way, the first side wall 21 can be folded relative to the second side wall 22 through the rotation of one of the first sub-side walls 211.
  • One of the first sub-side walls 211 can be rotatably connected with the corresponding second sub-side wall 221 through a rotating shaft, so as to realize rotation around the top edge of the second sub-side wall 221.
  • the first side wall 21 may include four first sub-side walls 211
  • the second side wall 22 may include four second sub-side walls 221.
  • the three first sub-side walls 211 and the corresponding second sub-side walls 221 After being disassembled and separated, the other first side wall 211 is made to rotate with the top edge of the corresponding second side wall 221.
  • the arrow in FIG. The two side walls 22 are folded, thereby reducing the size of the cage 100 in the set direction.
  • FIG. 5 is a schematic structural diagram of another embodiment of the experimental animal cage of the present application.
  • the side wall 20 includes a first side wall 21 and a second side wall 22 that are connected to each other, and the first side wall 21 is connected to the top wall 10, and the second side wall 22 is connected to the bottom wall.
  • the side wall 20 is foldable, or the first side wall 21 can be folded.
  • the first side wall 21 includes a plurality of uprights 222 and a first sub-side wall 211 of a grid structure capable of extending and contracting along the uprights 222.
  • the column 222 can be arranged parallel to the set direction.
  • the cage 100 has a first size in the set direction.
  • the cage The cage 100 has a second size in the set direction, and the first side wall 21 can be folded by the expansion and contraction of the first sub-side wall 211, thereby reducing the size of the cage 100 in the set direction.
  • top wall 10 and the column 222 are detachably connected.
  • the upright post 222 is retractable, so that after the first sub-side wall 211 is compressed along the upright post 222, the upright post 222 can also be contracted, thereby reducing the size of the cage 100 in the set direction as a whole.
  • the upright post 222 and the second side wall 22 can be rotatably connected, so that after the first sub-side wall 211 is compressed along the upright post 222, the upright post 222 can be rotated to reduce the clamping between the upright post and the second side wall 22 Angle, thereby reducing the size of the cage 100 in the set direction as a whole.
  • FIG. 6 is a schematic front view of an embodiment of the experimental animal cage of the present application.
  • the cage 100 may also include several support columns (not shown in the figure).
  • the side wall 20 is provided with a plurality of fixing holes 23, the supporting column can pass through the fixing hole 23 to extend into the inside of the cage 100, and the supporting column is detachably connected to the side wall 20.
  • the fixing hole 23 can be a circular hole with a diameter of 5 cm, and the support column can be used as a perch for non-human primates (such as monkeys).
  • non-human primates such as monkeys.
  • the material of the support column may be a material that is not resistant to wear and has a good touch.
  • the material of the support column may be selected from at least one of wood, plastic, rubber, and straw products.
  • the material of the support column can be selected from wood, plastic, rubber or straw products. It can also be a wooden stick covered with rubber or plastic material.
  • the material of the support column is a material that is not resistant to wear and has a better touch.
  • the animal’s sense of security further improves the reliability of the experimental results obtained.
  • the size of the fixing hole 23 can be flexibly adjusted under the premise of ensuring the stability of the cage 100 and preventing animals from escaping.
  • the size of the fixing hole 23 is adapted to the diameter of the support column.
  • the opening position of the fixing hole 23 can be flexibly adjusted according to needs, whether a supporting column is installed in the fixing hole 23, and the supporting column of which material is installed can also be set according to needs.
  • the side wall 20 may include four sub-side walls 24, and the fixing hole 23 may be opened in only one of the sub-side walls 24, or in multiple sub-side walls. On the side wall 24.
  • FIG. 7 is a partial structural diagram of an embodiment of the experimental animal cage of the present application.
  • the first cage 100 further includes a first moving wall 40 on which a number of sitting stools 41 are arranged.
  • the side wall 20 includes a plurality of sub-side walls 24, and the first moving wall 40 can move between two opposite sub-side walls 24.
  • the first moving wall 40 may be a frame structure to save materials and thereby save costs.
  • the side wall 20 may include four sub-side walls 24, and each sub-side wall 24 may include a first sub-side wall 211 and a second sub-side wall 221 .
  • the first moving wall 40 can move between the two opposite sub-side walls 24 through sliding devices such as slide rails provided on the bottom wall.
  • the seat 41 may be made of a material with a good touch and a strong and wear-resistant material, such as metal.
  • the first cage further includes a second moving wall 50, and the second moving wall 50 is provided with a plurality of through holes 51, and the through holes 51 correspond to the seat 41 in a one-to-one correspondence, so that the seat 41 can pass through the through holes 51.
  • the second moving wall 50 can move between the first moving wall 40 and the sub-side wall 24 opposite to the first moving wall 40.
  • the second moving wall 50 may be a grid structure to save material and facilitate air circulation inside the cage 100.
  • the second moving wall 50 can move to fit the first moving wall 40.
  • the first moving wall 40 can also be moved to a position where the sub-side wall 24 opposite to the first moving wall 40 fits.
  • the second moving wall 50 is attached to the first moving wall 40, and the first moving wall 40 can be attached to a sub-side wall 24; when the first moving wall 40 drives the second moving wall 50 together
  • it can be used to divide the space in the cage 100; since the seat 41 has a certain width, when the first moving wall 40 moves from one sub-side wall 24 to the other sub-side wall 24 is moved so that when the seat 41 is in contact with the other sub-side wall 24, by moving the second moving wall 50 to fit the other sub-side wall 24, the animal’s space can be further restricted or can be used to move the animal.
  • the animal’s space can be further restricted or can be used to move the animal.
  • first moving wall 40 and the second moving wall 50 are both foldable structures.
  • the first moving wall 40 and the second moving wall 50 When the first side wall 21 or the second moving wall 50 is expanded in the set direction, the first moving wall 40 and the second moving wall 50 have the first size in the set direction.
  • the first moving wall 40 and the second moving wall 50 When the first side wall 21 or the second moving wall 50 is folded along the set direction, the first moving wall 40 and the second moving wall 50 have the second size in the set direction.
  • the first moving wall 40 may include at least two first sub-moving walls hinged to each other
  • the second moving wall 50 may include at least two second sub-moving walls hinged to each other to achieve folding.
  • the first moving wall 40 and the second moving wall 50 can adapt to the change of the side wall 20.
  • the side wall 20 is in the unfolded state, the The first side wall 21 or the second moving wall 50 is also expanded in a set direction to meet the space requirement in the cage; when the side wall 20 is in a folded state, the first side wall 21 or the second moving wall 50 can be made Folding is also performed in the set direction, so that the cage 100 reduces its size in the set direction as a whole.
  • a first access door 25 is installed on the side wall 24 of the second moving wall 50 facing away from the first moving wall 40.
  • first access doors 25 There may be one or more first access doors 25.
  • the first access door 25 is opened on the sub-side wall 24 of the second moving wall 50 away from the first moving wall 40.
  • the second moving wall 50 can be moved to fit the sub-side wall 24 At this time, the space for the animal is restricted or can be used to remove the animal from the cage 100.
  • the first entry and exit door 25 is used for the entry and exit of experimental animals, so as to facilitate the sampling of experimental data or the transfer of experimental animals.
  • a food container (not shown in the figure) and a water bottle holder (not shown in the figure) can be provided on the side wall 24 of the second moving wall 50 facing away from the first moving wall 40.
  • the bottom wall is not provided on one side of the side wall 20, and multiple casters are installed;
  • the bottom wall is provided with a collection tank, and the collection tank is used to install a collection tray to collect animal excrement.
  • FIG. 8 is a schematic structural diagram of an embodiment of the experimental animal transfer device of the present application.
  • the experimental animal transfer device 200 includes a lifting platform 210, a transfer cage 220, and the experimental animal cage 100 described in any of the above embodiments.
  • a first access door 25 is opened on the side wall 20, and a second access door 25 is opened on the side wall 20 of the transfer cage 220.
  • the lifting platform 210 is used to transport the transfer cage 220 so that the second access door can be docked with the first access door 25.
  • the experimental animal transfer device 200 of this embodiment is provided with a lifting platform 210 to transport the transfer cage 220, for example, the transfer cage 220 is moved in the vertical height direction.
  • the lifting platform 210 is used to transport the transfer cage 220, which is convenient.
  • the docking of the second access door and the first access door 25 can improve the transfer efficiency and safety of experimental animals.
  • the experimental animal cage includes a bottom wall, a top wall and a side wall connecting the bottom wall and the top wall, and the side wall is foldable, so that when the side wall is in the unfolded state, the bottom wall, the top wall and The side walls are surrounded to form a first cage shape.
  • the cage In the first cage shape, the cage has a first size in a set direction to expand the living space of experimental animals; when the side walls are in a folded state, the bottom wall and the top The walls and side walls are folded to form a second cage shape.
  • the cage has a second size in the set direction, and the second size is smaller than the first size to facilitate the transfer and handling of the cage.
  • the applied experimental animal cage can change its size in a set direction through the folding of the side walls, so as to meet the living space requirements of the experimental animal while facilitating the transfer and transportation of the cage.

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  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Clinical Laboratory Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
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Abstract

本申请公开了一种实验动物笼具和实验动物转移装置。该实验动物笼具包括底壁、顶壁以及连接底壁和顶壁的侧壁，侧壁是可折叠的；在侧壁处于展开状态时，底壁、顶壁和侧壁围设形成第一笼体形态，在第一笼体形态下，笼具在设定方向具有第一尺寸；在侧壁处于折叠状态时，底壁、顶壁和侧壁折叠形成第二笼体形态，在第二笼体形态下，笼具在设定方向具有第二尺寸，第二尺寸小于第一尺寸。通过上述方式，本申请的实验动物笼具能够改变在设定方向上的尺寸，以在满足实验动物的生活空间需求的同时，便于进行笼具的转移和搬运。

Description

实验动物笼具和实验动物转移装置 【技术领域】
本申请涉及实验室动物饲养装置技术领域，特别是涉及验动物笼具和实验动物转移装置。
【背景技术】
在新药研发、动物营养学、脑科学等的研究过程中，通常需要将实验动物置于相应的饲养笼中进行实验结果跟踪，同时还要保证实验动物健康的生活环境。例如，作为与人类最相近的动物，非人灵长类模型(Non-human primate model)被广泛应用于研究情绪、认知、社交以及多种疾病的病理及治疗手段比如成瘾、抑郁、心血管疾病、癌症、艾滋病、多发性硬化症(Multiple sclerosis)、器官移植等。事实上，作为临床试验之前的最后一步，新的药物治疗手段一定会在非人灵长类动物上进行安全性和疗效的测试。
但是，目前的饲养笼通常尺寸单一，在实际使用中，缺乏灵活性和可拓展性，难以在现有实验设施条件下同时兼顾满足动物生存需求。
【发明内容】
本申请主要解决的技术问题是提供一种实验动物笼具，能够改变在设定方向上的尺寸，以在满足实验动物的生活空间需求的同时，便于进行笼具的转移和搬运。
为解决上述技术问题，本申请实施例采用的一个技术方案是：提供一种实验动物笼具，该实验动物笼具包括底壁、顶壁以及连接底壁和顶壁的侧壁，侧壁是可折叠的；在侧壁处于展开状态时，底壁、顶壁和侧壁围设形成第一笼体形态，在第一笼体形态下，笼具在设定方向具有第一尺寸；在侧壁处于折叠状态时，底壁、顶壁和侧壁折叠形成第二笼体形态，在第二笼体形态下，笼具在设定方向具有第二尺寸，第二尺寸小于第一尺寸。
其中，侧壁包括相互连接的第一侧壁和第二侧壁，且第一侧壁与顶壁连接，第二侧壁与底壁连接；第一侧壁能够相对于第二侧壁进行折叠。
其中，第一侧壁包括多个第一子侧壁，第二侧壁包括多个第二子侧壁，多 个第一子侧壁和多个第二子侧壁一一对应连接。
其中，每一第一子侧壁均与相邻的第一子侧壁可拆卸连接；顶壁与多个第一子侧壁均为可拆卸连接，或顶壁仅与其中一个第一子侧壁固定连接，并与其与第一子侧壁可拆卸连接；每一第一子侧壁均能够绕与其对应的第二子侧壁的顶边转动，以使得第一侧壁能够通过每一第一子侧壁的转动相对于第二侧壁进行折叠。
其中，第一侧壁与第二侧壁可滑动连接，使得第一侧壁的其中一个第一子侧壁能够移动到其相对的另一第一子侧壁的位置；且其中一个第一子侧壁能够绕与另一第一子侧壁对应的第二子侧壁的顶边转动，以使得第一侧壁能够通过其中一个第一子侧壁的转动相对于第二侧壁进行折叠。
其中，其中一个第一子侧壁能够绕与对应第二子侧壁的顶边转动，其余第一子侧壁均与对应第二子侧壁可拆卸连接，以使得第一侧壁能够通过其中一个第一子侧壁的转动相对于第二侧壁进行折叠。
其中，侧壁包括相互连接的第一侧壁和第二侧壁，且第一侧壁与顶壁连接，第二侧壁与底壁连接；第一侧壁能够进行折叠。
其中，第一侧壁包括多个立柱和能够沿立柱伸缩的网格结构；当第一侧壁沿立柱进行伸展时，笼具在设定方向具有第一尺寸，当第一侧壁沿立柱进行压缩时，笼具在设定方向具有第二尺寸。
其中，设定方向为垂直方向，第一尺寸大于等于2.5米，第二尺寸小于等于2米。
其中，笼具还包括若干支撑柱；侧壁上开设有若干固定孔，支撑柱能够穿过固定孔以伸入笼具的内部，支撑柱与侧壁可拆卸连接。
其中，支撑柱的材料选自木材、塑料、橡胶和秸秆制品中的至少一者。
其中，第一笼具还包括第一移动壁，第一移动壁上设置有若干坐凳；侧壁包括多个子侧壁，第一移动壁能够在两个相对的子侧壁之间移动。
其中，第一笼体还包括第二移动壁，第二移动壁开设有若干通孔，通孔与坐凳一一对应，使得坐凳能够穿过通孔；第二移动壁能够在第一移动壁和与第一移动壁相对的子侧壁之间移动。
其中，第一移动壁和第二移动壁均为可折叠结构；当第一侧壁或和第二移动壁沿设定方向进行展开时，第一移动壁和第二移动壁在设定方向具有第一尺寸；当第一侧壁或和第二移动壁沿设定方向进行折叠时，第一移动壁和第二移 动壁在设定方向具有第二尺寸。
其中，第二移动壁背离第一移动壁一侧的子侧壁上安装有第一进出门；第二移动壁背离第一移动壁一侧的上设置有食盒和水瓶架。
其中，底壁未设置有侧壁的一侧，安装有多个脚轮；
底壁开设有收集槽，收集槽用于安装收集盘，以收集动物的排泄物。
其中，实验动物转移装置包括升降台、转移笼和如权利要求1的实验动物笼具；
其中，侧壁上开设有第一进出门，转移笼的侧壁上开设有第二进出门；升降台用于运送转移笼，以使得第二进出门能够与第一进出门对接。
为解决上述技术问题，本申请实施例采用的另一个技术方案是：提供一种实验动物转移装置，该实验动物转移装置包括升降台、转移笼和如上述的实验动物笼具；其中，侧壁上开设有第一进出门，转移笼的一侧开设于第二进出门；升降台用于运送转移笼，以使得第二进出门能够与第一进出门对接。
本申请中，通过设置实验动物笼具包括底壁、顶壁以及连接底壁和顶壁的侧壁，且侧壁是可折叠的，使得在侧壁处于展开状态时，底壁、顶壁和侧壁围设形成第一笼体形态，在第一笼体形态下，笼具在设定方向具有第一尺寸，以扩大实验动物的生活空间；在侧壁处于折叠状态时，底壁、顶壁和侧壁折叠形成第二笼体形态，在第二笼体形态下，笼具在设定方向具有第二尺寸，第二尺寸小于第一尺寸，以利于笼具的转移和搬运，因而本申请的实验动物笼具通过侧壁的折叠，能够改变其在设定方向上的尺寸，以在满足实验动物的生活空间需求的同时，便于进行笼具的转移和搬运。
【附图说明】
为了更清楚地说明本申请实施例或现有技术中的技术方案，下面将对实施例或现有技术描述中所需要使用的附图作简单地介绍，显而易见地，下面描述中的附图仅仅是本申请的一些实施例，对于本领域普通技术人员来讲，在不付出创造性劳动的前提下，还可以根据这些附图获得其他的附图。
图1是本申请的实验动物笼具一实施例的第一笼体形态示意图；
图2是本申请的实验动物笼具一实施例的第二笼体形态示意图；
图3是本申请的实验动物笼具另一实施例的结构示意图；
图4是本申请的实验动物笼具再一实施例的结构示意图；
图5是本申请的实验动物笼具又一实施例的结构示意图；
图6是本申请的实验动物笼具一实施例的正视结构示意图；
图7是本申请的实验动物笼具一实施例的部分结构示意图；
图8是是本申请的实验动物转移装置一实施例的结构示意图。
【具体实施方式】
下面将结合本申请实施例中的附图，对本申请实施例中的技术方案进行清楚、完整地描述。可以理解的是，此处所描述的具体实施例仅用于解释本申请，而非对本申请的限定。另外为了便于描述，附图中仅示出了与本申请相关的部分而非全部结构。基于本申请中的实施例，本领域普通技术人员在没有作出创造性劳动前提下所获得的所有其他实施例，都属于本申请保护的范围。
本申请中的术语“第一”、“第二”等是用于区别不同对象，而不是用于描述特定顺序或结构。此外，术语“包括”和“具有”以及他们任何变形，意图在于覆盖不排他的包含。例如包含了一系列步骤或单元的过程、方法、系统、产品或设备没有限定于已列出的步骤或单元，而是可选地还包括没有列出的步骤或单元，或可选地还包括对于这些过程、方法、产品或设备固有的其他步骤或单元。
在本文中提及“实施例”意味着，结合实施例描述的特定特征、结构或特性可以包含在本申请的至少一个实施例中。在说明书中的各个位置出现该短语并不一定均是指相同的实施例，也不是与其他实施例互斥的独立的或备选的实施例。本领域技术人员显式地和隐式地理解的是，本文所描述的实施例可以与其他实施例相结合。
请结合参阅图1和图2，图1是本申请的实验动物笼具一实施例的第一笼体形态示意图，图2是本申请的实验动物笼具一实施例的第二笼体形态示意图。
实验动物笼具100包括底壁、顶壁10以及连接底壁和顶壁10的侧壁20，侧壁20是可折叠的。
在侧壁20处于展开状态时，底壁(图未示)、顶壁10和侧壁20围设形成第一笼体形态，在第一笼体形态下，笼具100在设定方向具有第一尺寸。
在侧壁20处于折叠状态时，底壁、顶壁10和侧壁20折叠形成第二笼体形 态，在第二笼体形态下，笼具100在设定方向具有第二尺寸，第二尺寸小于第一尺寸。
可选地，设定方向可以是垂直方向，以用于调整笼具100的高度，有利于满足部分种类的实验动物对垂直生活空间的需求，例如有利于满足非人灵长类动物的攀爬习性；也可以是水平方向，以用于调整笼具100的水平长度，有利于满足部分种类的实验动物对水平生活空间的需求，例如有利于满足啮齿类动物需要在水平生活空间不断爬行的习性。
其中，设定方向和第一尺寸的具体数值可根据实际准备所笼养的动物的生活习性和实验室的房间高度来确定。第二尺寸的具体数值可根据笼具100转移过程中可能会遇到的限制来确定，例如运送车辆的高度或宽度，实验室的门框高度或宽度等。
可选地，笼具100在第一笼体形态下可呈立方体型。当然，也可呈其他形状，例如立方体型和球型的结合等，本实施例在此不做限制。
本实施例中，通过设置实验动物笼具100包括底壁、顶壁10以及连接底壁和顶壁10的侧壁20，且侧壁20是可折叠的，使得在侧壁20处于展开状态时，底壁、顶壁10和侧壁20围设形成第一笼体形态，在第一笼体形态下，笼具100在设定方向具有第一尺寸，以扩大实验动物的生活空间；在侧壁20处于折叠状态时，底壁、顶壁10和侧壁20折叠形成第二笼体形态，在第二笼体形态下，笼具100在设定方向具有第二尺寸，第二尺寸小于第一尺寸，以利于笼具100的转移和搬运，因而本申请的实验动物笼具100通过侧壁20的折叠，能够改变其在设定方向上的尺寸，以在满足实验动物的生活空间需求的同时，便于进行笼具100的转移和搬运。
在一种应用场景中，本实施例的实验动物笼具100可用于非人灵长类的笼养。在实验室中，非人灵长类动物一般处于笼养状态，因此充足的笼内空间是非人灵长类动物福利的关键要素之一。世界上有多个国家和组织制定了饲养非人灵长类动物的空间标准。以单只3岁左右、3.5公斤的猕猴为例，在美国，动物福利法条例(Animal Welfare Act Regulations，AWAR)及实验室或农业动物的饲养和使用指南(The Guide to the Care and Use of Laboratory Animals or its agricultural counterpart)中规定其占有的地面空间不得低于0.4平方米，高度不得低于0.76平方米。此外，指南中规定的标准由于国际实验动物护理评估与认可协会(The Association for Assessment and Accreditation of Laboratory Animal  Care International，AAALAC)的推广，被超过41个国家所采纳。在欧洲，用于实验和其他科学目的的脊椎动物保护欧洲公约(The European Convention for the Protection of Vertebrate Animals used for Experimental and Other Scientific Purposes，ETS-123)中规定，该猕猴活动的地面空间不得低于2.0平方米，高度不得低于1.8平方米，占有空间不得低于1.8立方米。
尽管上述所有标准都保证了非人灵长类动物能够表现出物种特异的行为和姿势，对大多数非人灵长类动物而言，笼具100的高度更加关键，这与它们的树栖天性一致。当收到惊吓时，它们往往会攀爬至高处以躲避危险。如果缺乏足够的空间尤其是高度去逃避威胁，或笼养环境过于单调，非人灵长类往往会表现出诸如过度理毛、原地绕圈等刻板行为，这意味着它们的动物福利没有得到保证，在它们身上采集的数据也是不可靠的。同时，由于目前常规的门一般是2.1米高，超过这一高度的笼具100难以跨房间转移，另外，过高的笼具100也会提高操作难度，这些因素限制了对笼具100高度的扩增。
因此，本应用场景中，设定方向可为垂直方向，第一尺寸可大于等于2.5米，例如2.5米、3米、3.5米、4米或更高，以拓展笼具100的高度，满足非人灵长类动物攀爬的天性以及探索新环境的好奇心；第二尺寸可小于等于2米，例如2米、1.8米、1.5米或更低，以降低笼具100的高度，方便笼具100通过门进行转移。笼具100在第一笼体形态下可呈立方体型，底壁的面积不小于1平方米，例如底壁的长和宽各大于1米。
可选地，侧壁20包括相互连接的第一侧壁21和第二侧壁22，且第一侧壁21与顶壁10连接，第二侧壁22与底壁连接。
其中，侧壁20是可折叠的可以是：第一侧壁21能够相对于第二侧壁22进行折叠。
可选地，第一侧壁21可包括多个第一子侧壁211，第二侧壁22可包括多个第二子侧壁221，多个第一子侧壁211的底边和多个第二子侧壁221的顶边一一对应连接。
可选地，多个第一子侧壁211的底边和多个第二子侧壁221的顶边一一对应连接后，每一第一子侧壁211的底边和与其对应的第二子侧壁221的顶边相接触。
以笼具100在第一笼体形态下可呈长方体型为例，第一侧壁21可包括四个第一子侧壁211，第二侧壁22可包括四个第二子侧壁221，每一第一子侧壁211 的底边与对应的第二子侧壁221的顶边相接触，以围合成笼具100。第一子侧壁211与对应的第二子侧壁221可以是卡扣连接或通过设置在第一子侧壁211和第二子侧壁221的连接件连接。
可选地，多个第一子侧壁211与底壁之间、多个第一子侧壁211相互之间可以是是活动连接的，使得多个第一子侧壁211可相对于笼具100本体进行开合，当多个笼具100之间通过边缘设置的卡扣等固定结构进行连接后，打开多个笼具100之间相邻第一子侧壁211，可使得多个笼具100之间的空间得以连通，从而进一步拓展笼具100内的空间。
请继续参与图2，在一种实施方式中，第一侧壁21能够相对于第二侧壁22进行折叠可以是：
每一第一子侧壁211均与相邻的第一子侧壁211可拆卸连接。
每一第一子侧壁211均与相邻的第一子侧壁211可拆卸连接是指多个第一子侧壁211之间均可拆卸连接，例如是多个第一子侧壁211之间通过卡扣连接或插销连接等。
顶壁10与多个第一子侧壁211均为可拆卸连接，或顶壁10仅与其中一个第一子侧壁211固定连接，并与其与第一子侧壁211可拆卸连接。
顶壁10与第一子侧壁211可拆卸连接，例如是顶壁10与第一子侧壁211通过卡扣连接或插销连接等。每一第一子侧壁211均能够绕与其对应的第二子侧壁221的顶边转动，以使得第一侧壁21能够通过每一第一子侧壁211的转动相对于第二侧壁22进行折叠。
每一第一子侧壁211均能够绕与其对应的第二子侧壁221的顶边转动，可以是每一第一子侧壁211与其对应的第二子侧壁221均通过可转动的连接件连接，例如通过铰链连接。
当需要使笼具100由第一笼体形态转变为第二笼体形态时，可使顶壁10与一第一子侧壁211保持固定连接，并使顶壁10与其他第一子侧壁211分离，多个第一子侧壁211之间也分离，从而使得第一子侧壁211绕与其对应的第二子侧壁221的顶边转动，以减小第一子侧壁211和对应的第二子侧壁221之间的夹角，实现折叠，从而降低笼具100在设定方向上的尺寸。
请参阅图3，图3是本申请的实验动物笼具另一实施例的结构示意图。
在一种实施方式中，第一侧壁21能够相对于第二侧壁22进行折叠可以是：
第一侧壁21与第二侧壁22可滑动连接，使得第一侧壁21的其中一个第一 子侧壁211能够移动到其相对的另一第一子侧壁211的位置。
且其中一个第一子侧壁211能够绕与另一第一子侧壁211对应的第二子侧壁221的顶边转动，以使得第一侧壁21能够通过其中一个第一子侧壁211的转动相对于第二侧壁22进行折叠。
当第一侧壁21处于第一状态时，第一侧壁21与第二侧壁22可通过可拆卸的连接件固定，以形成第一笼体形态；如图3所示，当第一侧壁21处于第二状态时，第一侧壁21与第二侧壁22相对分离且移动第一侧壁21的其中一个第一子侧壁211移动到其相对的另一第一子侧壁211的位置，使得其中一个第一子侧壁211能够绕与另一第一子侧壁211对应的第二子侧壁221的顶边转动，图3中箭头表示转动方向，以实现折叠，最终形成第二笼体形态。
第一侧壁21与第二侧壁22可滑动连接，可以是第一侧壁21的底边与第二侧壁22的顶边通过滑轨30连接，使得第一侧壁21可通过滑轨30相对于第二侧壁22进行滑动。
第一侧壁21可整体从第二侧壁22的一端滑动至第二侧壁22的另一端，即使得其中一个第一子侧壁211能够互动至与其对应的另一第一子侧壁211的位置。进而使得其中一个第一子侧壁211能够绕与该另一第一子侧壁211对应的第二子侧壁221的顶边转动，实现第一侧壁21能够整体相对于第二侧壁22进行折叠，从而降低笼具100在设定方向上的尺寸。
请参阅图4，图4是本申请的实验动物笼具再一实施例的结构示意图。
在一种实施方式中，其中一个第一子侧壁211能够绕与对应第二子侧壁221的顶边转动，其余第一子侧壁211均与对应第二子侧壁221可拆卸连接，以使得第一侧壁21能够通过其中一个第一子侧壁211的转动相对于第二侧壁22进行折叠。
其中一个第一子侧壁211可通过转轴与对应第二子侧壁221可转动地连接，以实现绕第二子侧壁221的顶边转动。
以笼具100在第一笼体形态下可呈长方体型为例，第一侧壁21可包括四个第一子侧壁211，第二侧壁22可包括四个第二子侧壁221，在实际使用中，如图四所示，若要将笼具100由第一笼体形态转换到第二笼体形态，可先将三个第一子侧壁211与对应第二子侧壁221经拆卸后分离，然后使得另一个第一子侧壁211均与对应第二子侧壁221的顶边转动，图4中箭头表示转动方向，则可实现第一侧壁21能够整体相对于第二侧壁22进行折叠，从而降低笼具100 在设定方向上的尺寸。
请参阅图5，图5是本申请的实验动物笼具又一实施例的结构示意图。
本实施例中，侧壁20包括相互连接的第一侧壁21和第二侧壁22，且第一侧壁21与顶壁10连接，第二侧壁22与底壁连接。
其中，侧壁20是可折叠的，还可以是第一侧壁21能够进行折叠。
例如，第一侧壁21包括多个立柱222和能够沿立柱222伸缩的网格结构的第一子侧壁211。
立柱222可平行于设定方向设置，当第一子侧壁211沿立柱222进行伸展时，笼具100在设定方向具有第一尺寸，当第一侧壁21沿立柱222进行压缩时，笼具100在设定方向具有第二尺寸，通过第一子侧壁211的伸缩可实现第一侧壁21的折叠，从而降低笼具100在设定方向上的尺寸。
可选地，顶壁10与立柱222可拆卸连接。
可选地，立柱222是可伸缩的，从而可在第一子侧壁211沿立柱222进行压缩后，立柱222也可收缩，从而在整体上降低笼具100在设定方向上的尺寸。
可选地，立柱222与第二侧壁22可转动连接，从而可在第一子侧壁211沿立柱222进行压缩后，立柱222可以通过转动减小立柱与第二侧壁22之间的夹角，从而在整体上降低笼具100在设定方向上的尺寸。
请参阅图6，图6是本申请的实验动物笼具一实施例的正视结构示意图。
可选地，笼具100还可包括若干支撑柱(图未示)。
侧壁20上开设有若干固定孔23，支撑柱能够穿过固定孔23以伸入笼具100的内部，支撑柱与侧壁20可拆卸连接。
在一种应用场景中，固定孔23可以是直径为5厘米圆孔，支撑柱可作为非人灵长类动物(例如猴子)的栖木，通过在侧壁20上安装若干支撑柱，可进一步利于满足非人灵长类攀爬的天性，以及探索新鲜物体的天性。
可选地，支撑柱的材料可为不耐损耗且触感较好的材料。
可选地，支撑柱的材料可选自木材、塑料、橡胶和秸秆制品中的至少一者。例如，支撑柱的材料可选自木材、塑料、橡胶或秸秆制品。也可以是，包覆有橡胶或塑料材料的木棍。
相比如金属等坚硬且冰冷的材料，支撑柱的材料为不耐损耗材料且触感较好的材料，可供动物(例如非人灵长类动物)发泄破坏欲，让它们觉得能够掌控环境，增强动物的安全感，从而进一步提高所获得的实验结果的可靠性。
固定孔23的尺寸在保证笼具100的稳固性及防止动物逃逸的前提下可灵活调整。固定孔23的尺寸与支撑柱的直径相适配。固定孔23开设的位置可灵根据需要调整，固定孔23中是否安装支撑柱，安装何种材料的支撑柱也可以根据需要设置。
以笼具100在第一笼体形态下可呈长方体型为例，侧壁20可包括四个子侧壁24，固定孔23可仅开设在其中一个子侧壁24上，也可以开设在多个子侧壁24上。
请参阅图7，图7是本申请的实验动物笼具一实施例的部分结构示意图。
可选地，第一笼具100还包括第一移动壁40，第一移动壁40上设置有若干坐凳41。
侧壁20包括多个子侧壁24，第一移动壁40能够在两个相对的子侧壁24之间移动。
可选地，第一移动壁40可为框架结构，以节省材料，进而节约成本。
以笼具100在第一笼体形态下可呈长方体型为例，侧壁20可包括四个子侧壁24，每个子侧壁24均可包括第一子侧壁211和第二子侧壁221。
第一移动壁40可以通过设置在底壁上的滑轨等滑动装置，在两个相对的子侧壁24之间移动。
可选地，坐凳41可选用触感较好并坚固耐磨的材质，例如金属。
可选地，第一笼体还包括第二移动壁50，第二移动壁50开设有若干通孔51，通孔51与坐凳41一一对应，使得坐凳41能够穿过通孔51。
第二移动壁50能够在第一移动壁40和与第一移动壁40相对的子侧壁24之间移动。
可选地，第二移动壁50可为网格结构，以节省材料，且有利于笼具100内部的空气流通。
由于通孔51与坐凳41一一对应且坐凳41能够穿过通孔51，因此第二移动壁50可移动至与第一移动壁40相贴合。可选地，第一移动壁40还可移动至与第一移动壁40相对的子侧壁24相贴合的位置。
一般情况下，第二移动壁50与第一移动壁40相贴合，且第一移动壁40可与一个子侧壁24相贴合；当第一移动壁40带动第二移动壁50一起在两个相对的子侧壁24之间移动时，可用于分割笼具100内的空间；由于坐凳41具有一定的宽度，当第一移动壁40从一个子侧壁24向另一个子侧壁24移动使得坐凳 41与另一子侧壁24相接触时，通过将第二移动壁50移动至与另一个子侧壁24相贴合时，可进一步限制动物的空间或可用于将动物移出笼具100。
可选地，第一移动壁40和第二移动壁50均为可折叠结构。
当第一侧壁21或和第二移动壁50沿设定方向进行展开时，第一移动壁40和第二移动壁50在设定方向具有第一尺寸。
当第一侧壁21或和第二移动壁50沿设定方向进行折叠时，第一移动壁40第二移动壁50在设定方向具有第二尺寸。
例如，第一移动壁40可包括至少两个相互铰接的第一子移动壁，第二移动壁50可包括至少两个相互铰接的第二子移动壁，以实现折叠。
通过设置第一移动壁40和第二移动壁50均为可折叠结构，使得第一移动壁40和第二移动壁50能够适应侧壁20的变化，当侧壁20处于展开状态时，可使得第一侧壁21或和第二移动壁50也沿设定方向进行展开，以满足笼内空间需要；当侧壁20处于折叠状态时，可使得第一侧壁21或和第二移动壁50也沿设定方向进行折叠，以使得笼具100在整体上降低其在设定方向上的尺寸。
可选地，第二移动壁50背离第一移动壁40一侧的子侧壁24上安装有第一进出门25。
第一进出门25可以是一个或多个。
第一进出门25开设在第二移动壁50背离第一移动壁40一侧的子侧壁24上，在使用时，可通过将第二移动壁50移动至与该子侧壁24相贴合时，从而限制动物的空间或可用于将动物移出笼具100。
第一进出门25用于供实验动物出入，以便于进行实验数据采样或实验动物的转移等。
第二移动壁50背离第一移动壁40一侧的子侧壁24上可设置有食盒(图未示)和水瓶架(图未示)。
可选地，底壁未设置有侧壁20的一侧，安装有多个脚轮；
底壁开设有收集槽，收集槽用于安装收集盘，以收集动物的排泄物。
请参阅图8，图8是是本申请的实验动物转移装置一实施例的结构示意图。
本实施例中，实验动物转移装置200包括升降台210、转移笼220和如上任一实施例所述的实验动物笼具100。
其中，侧壁20上开设有第一进出门25，转移笼220的侧壁20上开设有第二进出门。
升降台210用于运送转移笼220，以使得第二进出门能够与第一进出门25对接。
本实施例的实验动物转移装置200通过设置升降台210以运送转移笼220，例如在垂直高度方向上移动转移笼220，当笼具100较高时，使用升降台210运送转移笼220，可方便地进行第二进出门和第一进出门25的对接，能够提高实验动物转移效率和安全性。
本申请中，通过设置实验动物笼具包括底壁、顶壁以及连接底壁和顶壁的侧壁，且侧壁是可折叠的，使得在侧壁处于展开状态时，底壁、顶壁和侧壁围设形成第一笼体形态，在第一笼体形态下，笼具在设定方向具有第一尺寸，以扩大实验动物的生活空间；在侧壁处于折叠状态时，底壁、顶壁和侧壁折叠形成第二笼体形态，在第二笼体形态下，笼具在设定方向具有第二尺寸，第二尺寸小于第一尺寸，以利于笼具的转移和搬运，因而本申请的实验动物笼具通过侧壁的折叠，能够改变其在设定方向上的尺寸，以在满足实验动物的生活空间需求的同时，便于进行笼具的转移和搬运。
以上仅为本申请的实施方式，并非因此限制本申请的专利范围，凡是利用本申请说明书及附图内容所作的等效结构或等效流程变换，或直接或间接运用在其他相关的技术领域，均同理包括在本申请的专利保护范围内。

Claims (17)

  1. 一种实验动物笼具，其特征在于，所述笼具包括底壁、顶壁以及连接所述底壁和所述顶壁的侧壁，所述侧壁是可折叠的；
    在所述侧壁处于展开状态时，所述底壁、所述顶壁和所述侧壁围设形成第一笼体形态，在所述第一笼体形态下，所述笼具在设定方向具有第一尺寸；
    在所述侧壁处于折叠状态时，所述底壁、所述顶壁和所述侧壁折叠形成第二笼体形态，在所述第二笼体形态下，所述笼具在所述设定方向具有第二尺寸，所述第二尺寸小于所述第一尺寸。
  2. 根据权利要求1所述的实验动物笼具，其特征在于，
    所述侧壁包括相互连接的第一侧壁和第二侧壁，且所述第一侧壁与所述顶壁连接，所述第二侧壁与所述底壁连接；
    所述第一侧壁能够相对于所述第二侧壁进行折叠。
  3. 根据权利要求2所述的实验动物笼具，其特征在于，
    所述第一侧壁包括多个第一子侧壁，所述第二侧壁包括多个第二子侧壁，多个所述第一子侧壁和多个所述第二子侧壁一一对应连接。
  4. 根据权利要求3所述的实验动物笼具，其特征在于，
    每一所述第一子侧壁均与相邻的所述第一子侧壁可拆卸连接；
    所述顶壁与多个所述第一子侧壁均为可拆卸连接，或所述顶壁仅与其中一个所述第一子侧壁固定连接，并与其与所述第一子侧壁可拆卸连接；
    每一所述第一子侧壁均能够绕与其对应的所述第二子侧壁的顶边转动，以使得所述第一侧壁能够通过每一所述第一子侧壁的转动相对于所述第二侧壁进行折叠。
  5. 根据权利要求3所述的实验动物笼具，其特征在于，
    所述第一侧壁与所述第二侧壁可滑动连接，使得所述第一侧壁的其中一个所述第一子侧壁能够移动到其相对的另一所述第一子侧壁的位置；
    且其中一个所述第一子侧壁能够绕与另一所述第一子侧壁对应的所述第二子侧壁的顶边转动，以使得所述第一侧壁能够通过其中一个所述第一子侧壁的转动相对于所述第二侧壁进行折叠。
  6. 根据权利要求3所述的实验动物笼具，其特征在于，
    其中一个所述第一子侧壁能够绕与对应所述第二子侧壁的顶边转动，其余 所述第一子侧壁均与对应所述第二子侧壁可拆卸连接，以使得所述第一侧壁能够通过其中一个所述第一子侧壁的转动相对于所述第二侧壁进行折叠。
  7. 根据权利要求1所述的实验动物笼具，其特征在于，
    所述侧壁包括相互连接的第一侧壁和第二侧壁，且所述第一侧壁与所述顶壁连接，所述第二侧壁与所述底壁连接；
    所述第一侧壁能够进行折叠。
  8. 根据权利要求7所述的实验动物笼具，其特征在于，所述第一侧壁包括多个立柱和能够沿所述立柱伸缩的网格结构；
    当所述第一侧壁沿所述立柱进行伸展时，所述笼具在所述设定方向具有第一尺寸，当所述第一侧壁沿所述立柱进行压缩时，所述笼具在所述设定方向具有第二尺寸。
  9. 根据权利要求1所述的实验动物笼具，其特征在于，
    所述设定方向为垂直方向，所述第一尺寸大于等于2.5米，所述第二尺寸小于等于2米。
  10. 根据权利要求1所述的实验动物笼具，其特征在于，所述笼具还包括若干支撑柱；
    所述侧壁上开设有若干固定孔，所述支撑柱能够穿过所述固定孔以伸入所述笼具的内部，所述支撑柱与所述侧壁可拆卸连接。
  11. 根据权利要求10所述的实验动物笼具，其特征在于，
    所述支撑柱的材料选自木材、塑料、橡胶和秸秆制品中的至少一者。
  12. 根据权利要求1所述的实验动物笼具，其特征在于，
    所述第一笼具还包括第一移动壁，所述第一移动壁上设置有若干坐凳；
    所述侧壁包括多个子侧壁，所述第一移动壁能够在两个相对的所述子侧壁之间移动。
  13. 根据权利要求12所述的实验动物笼具，其特征在于，
    所述第一笼体还包括第二移动壁，所述第二移动壁开设有若干通孔，所述通孔与所述坐凳一一对应，使得所述坐凳能够穿过所述通孔；
    所述第二移动壁能够在所述第一移动壁和与所述第一移动壁相对的所述子侧壁之间移动。
  14. 根据权利要求13所述的实验动物笼具，其特征在于，所述第一移动壁和所述第二移动壁均为可折叠结构；
    当所述第一侧壁或和所述第二移动壁沿所述设定方向进行展开时，所述第一移动壁和所述第二移动壁在所述设定方向具有第一尺寸；
    当所述第一侧壁或和所述第二移动壁沿所述设定方向进行折叠时，所述第一移动壁和所述第二移动壁在所述设定方向具有第二尺寸。
  15. 根据权利要求12所述的实验动物笼具，其特征在于，
    所述第二移动壁背离所述第一移动壁一侧的所述子侧壁上安装有第一进出门；
    所述第二移动壁背离所述第一移动壁一侧的上设置有食盒和水瓶架。
  16. 根据权利要求1所述的实验动物笼具，其特征在于，
    所述底壁未设置有所述侧壁的一侧，安装有多个脚轮；
    所述底壁开设有收集槽，所述收集槽用于安装收集盘，以收集动物的排泄物。
  17. 一种实验动物转移装置，其特征在于，所述实验动物转移装置包括升降台、转移笼和如权利要求1所述的实验动物笼具；
    其中，所述侧壁上开设有第一进出门，所述转移笼的侧壁上开设有第二进出门；
    所述升降台用于运送所述转移笼，以使得所述第二进出门能够与所述第一进出门对接。
PCT/CN2020/089064 2020-05-07 2020-05-07 实验动物笼具和实验动物转移装置 WO2021223187A1 (zh)

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