WO2021222597A3 - Rapid diagnostic immunoassay for presence of antibodies - Google Patents

Rapid diagnostic immunoassay for presence of antibodies Download PDF

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Publication number
WO2021222597A3
WO2021222597A3 PCT/US2021/029936 US2021029936W WO2021222597A3 WO 2021222597 A3 WO2021222597 A3 WO 2021222597A3 US 2021029936 W US2021029936 W US 2021029936W WO 2021222597 A3 WO2021222597 A3 WO 2021222597A3
Authority
WO
WIPO (PCT)
Prior art keywords
antibodies
rapid diagnostic
diagnostic immunoassay
immunoassay
reagent
Prior art date
Application number
PCT/US2021/029936
Other languages
French (fr)
Other versions
WO2021222597A2 (en
Inventor
Bobby Brooke HERRERA
Irene Bosch
Adam GOMEZ
Nol SALCEDO
Ankita REDDY
Original Assignee
E25Bio, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by E25Bio, Inc. filed Critical E25Bio, Inc.
Publication of WO2021222597A2 publication Critical patent/WO2021222597A2/en
Publication of WO2021222597A3 publication Critical patent/WO2021222597A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G01N33/54387—Immunochromatographic test strips
    • G01N33/54388—Immunochromatographic test strips based on lateral flow
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/165—Coronaviridae, e.g. avian infectious bronchitis virus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/10—Detection of antigens from microorganism in sample from host

Abstract

The subject matter disclosed herein relates to an immunoassay for detecting antibodies in a biological sample from a subject comprising a capture reagent immobilized on a solid support; a detection reagent; and a visualizing reagent.
PCT/US2021/029936 2020-04-30 2021-04-29 Rapid diagnostic immunoassay for presence of antibodies WO2021222597A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063018318P 2020-04-30 2020-04-30
US63/018,318 2020-04-30

Publications (2)

Publication Number Publication Date
WO2021222597A2 WO2021222597A2 (en) 2021-11-04
WO2021222597A3 true WO2021222597A3 (en) 2021-12-16

Family

ID=78374247

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2021/029936 WO2021222597A2 (en) 2020-04-30 2021-04-29 Rapid diagnostic immunoassay for presence of antibodies

Country Status (1)

Country Link
WO (1) WO2021222597A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210356464A1 (en) * 2020-05-05 2021-11-18 Cellex, Inc. Serological assays for diagnosing or confirming covid-19 virus infections

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070092938A1 (en) * 2003-07-15 2007-04-26 Temasek Life Sciences Laboratory Diagnostics for sars virus
US20090061534A1 (en) * 2007-09-01 2009-03-05 Stephen Paul Sharrock Assay Device with Shared Zones
US20180372755A1 (en) * 2017-06-22 2018-12-27 Massachusetts Institute Of Technology Multiplexed Immunoassay for Detecting Biomarkers of Disease

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070092938A1 (en) * 2003-07-15 2007-04-26 Temasek Life Sciences Laboratory Diagnostics for sars virus
US20090061534A1 (en) * 2007-09-01 2009-03-05 Stephen Paul Sharrock Assay Device with Shared Zones
US20180372755A1 (en) * 2017-06-22 2018-12-27 Massachusetts Institute Of Technology Multiplexed Immunoassay for Detecting Biomarkers of Disease

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BURBELO PETER D., RIEDO FRANCIS X., MORISHIMA CHIHIRO, RAWLINGS STEPHEN, SMITH DAVEY, DAS SANCHITA, STRICH JEFFREY R., CHERTOW DAN: "Detection of Nucleocapsid Antibody to SARS-CoV-2 is More Sensitive than Antibody to Spike Protein in COVID-19 Patients", MEDRXIV, 24 April 2020 (2020-04-24), pages 1 - 24, XP055818503, Retrieved from the Internet <URL:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239070/pdf/nihpp-2020.04.20.20071423.pdf> [retrieved on 20210628], DOI: 10.1101/2020.04.20.20071423 *
DATABASE Nucleotide NCBI; 17 January 2020 (2020-01-17), ANONYMOUS: "Wuhan seafood market pneumonia virus isolate Wuhan-Hu-1, complete genome", XP055840913, retrieved from NCBI Database accession no. MN908947.3 *

Also Published As

Publication number Publication date
WO2021222597A2 (en) 2021-11-04

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