WO2021208776A1 - Système à ultrasons - Google Patents

Système à ultrasons Download PDF

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Publication number
WO2021208776A1
WO2021208776A1 PCT/CN2021/085688 CN2021085688W WO2021208776A1 WO 2021208776 A1 WO2021208776 A1 WO 2021208776A1 CN 2021085688 W CN2021085688 W CN 2021085688W WO 2021208776 A1 WO2021208776 A1 WO 2021208776A1
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WIPO (PCT)
Prior art keywords
ultrasound
module
signal
imaging device
image
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PCT/CN2021/085688
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English (en)
Chinese (zh)
Inventor
汪帝
冯丰
张珏
郭颖
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南京超维景生物科技有限公司
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Priority claimed from CN202010295631.6A external-priority patent/CN111345849A/zh
Priority claimed from CN202020560711.5U external-priority patent/CN212346569U/zh
Application filed by 南京超维景生物科技有限公司 filed Critical 南京超维景生物科技有限公司
Publication of WO2021208776A1 publication Critical patent/WO2021208776A1/fr

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves

Definitions

  • This application relates to the technical field of signal processing, in particular to ultrasound systems.
  • the existing ultrasound equipment is bulky, not easy to be moved, and its application scenarios are very limited.
  • the existing ultrasound equipment is a local complete device that integrates ultrasound signal transmission and recovery functions, image reconstruction functions, image post-processing functions, and terminal display functions, it is difficult to deal with the rapid speed of related technologies (such as image reconstruction technology). Upgrade and update.
  • the embodiment of the present application provides an ultrasound system.
  • the embodiment of the present application provides an ultrasound system, which includes a front-end device and a cloud imaging device signally connected to the front-end device.
  • the front-end device is used to determine the ultrasound control information that can control the ultrasound signal emitted by the ultrasound probe, and based on the ultrasound echo signal corresponding to the ultrasound signal to generate the ultrasound imaging signal that meets the preset conditions
  • the cloud imaging device is used to generate the ultrasound imaging signal based on the ultrasound echo signal.
  • the ultrasound probe includes multiple ultrasound channels
  • the cloud imaging device includes a data pre-processing module and an image reconstruction module signally connected to the data pre-processing module.
  • the ultrasound imaging signal undergoes parallel demodulation processing operations to generate demodulated information; the image reconstruction module is used to perform parallel image reconstruction operations based on the demodulated information to generate first ultrasound image information.
  • the cloud imaging device further includes an image post-processing module signally connected to the image reconstruction module, wherein the image post-processing module is used to perform image post-processing on the first ultrasound image information generated by the image reconstruction module Operate to generate second ultrasound image information.
  • the cloud imaging device further includes a scheduling module signally connected to the data pre-processing module, the image reconstruction module, and the image post-processing module, wherein the scheduling module is used to manage the computing nodes in the cloud imaging device.
  • the front-end device includes a beam forming module and an ultrasonic radio frequency data acquisition module.
  • the beam forming module is signally connected to the ultrasonic probe and the cloud imaging device, and the ultrasonic radio frequency data acquisition module is signally connected to the ultrasonic probe.
  • the module is used to determine ultrasound control information based on the cloud imaging device, and to control the ultrasound signal emitted by the ultrasound probe based on the ultrasound control information; the ultrasound radio frequency data acquisition module is used to convert the ultrasound echo signal recovered by the ultrasound probe into ultrasound imaging that meets the preset conditions Signal.
  • the front-end device further includes a data compression module signally connected to the ultrasound radio frequency data acquisition module, and the data compression module is used to perform parallel data compression operations on the ultrasound imaging signal.
  • the ultrasound probe includes multiple ultrasound channels
  • the data compression module includes multiple compression units
  • the ultrasound probe includes a plurality of array elements
  • the beam forming module includes a dual-port random access memory
  • the dual-port random access memory is used to control the output information of the plurality of array elements to form the spatial direction of the beam sex.
  • the ultrasound system further includes an ultrasound probe signally connected to the front-end device, and the ultrasound probe is used to transmit ultrasound signals based on the ultrasound control information determined by the front-end device, and receive ultrasound echo signals corresponding to the ultrasound signals .
  • the ultrasound system further includes an ultrasound display device signally connected to the cloud imaging device, and the ultrasound display device is configured to display ultrasound images based on ultrasound image information generated by the cloud imaging device.
  • the signal connection between the cloud imaging device and the ultrasonic display device is implemented based on a network with a preset transmission speed.
  • the signal connection between the front-end device and the cloud imaging device is implemented based on a network with a preset transmission speed.
  • the ultrasound system provided in the embodiments of the present application simplifies the structure of the front-end device by separating the front-end device and the cloud imaging device, and integrates the function of generating ultrasound image information based on the ultrasound imaging signal into the cloud imaging device.
  • the miniaturization of the front-end device provides a prerequisite.
  • the ultrasound system provided by the embodiments of the present application integrates the function of generating ultrasound image information based on ultrasound imaging signals into the cloud imaging device, which provides convenience for the rapid upgrade and update of ultrasound imaging technology.
  • Fig. 1 is a schematic structural diagram of an ultrasound system provided by an exemplary embodiment of this application.
  • FIG. 2 is a schematic structural diagram of a cloud imaging device in an ultrasound system provided by an exemplary embodiment of this application.
  • Fig. 3 is a schematic structural diagram of a front-end device in an ultrasound system provided by an exemplary embodiment of this application.
  • FIG. 4 is a schematic structural diagram of an ultrasound system provided by another exemplary embodiment of this application.
  • Fig. 1 is a schematic structural diagram of an ultrasound system provided by an exemplary embodiment of this application.
  • the ultrasound system 10 provided by the embodiment of the present application includes a front-end device 11 and a cloud imaging device 12 signally connected to the front-end device 11.
  • the front-end device 11 is used to determine ultrasound control information capable of controlling the ultrasound signal emitted by the ultrasound probe, and generate an ultrasound imaging signal that meets the preset conditions based on the ultrasound echo signal corresponding to the ultrasound signal emitted by the ultrasound probe.
  • the cloud imaging device 12 is used to generate ultrasound image information based on the ultrasound imaging signal generated by the front-end device 11.
  • the preset condition refers to that the signal form is a digital signal form.
  • the front-end device 11 converts the ultrasonic echo signal in the form of an analog signal recovered by the ultrasonic probe into an ultrasonic imaging signal in the form of a digital signal.
  • the ultrasound control information refers to control sequence information capable of controlling the ultrasound beam emitted by the ultrasound probe.
  • the front-end device 11 is a local device that is placed in a preset ultrasonic inspection space together with an ultrasonic probe and other devices, so that the user can use the front-end device 11 to achieve the purpose of ultrasonic inspection.
  • the cloud imaging device 12 is a non-local device (such as a remote server or a cloud server) that places related functional modules in the "cloud”. That is, the front-end device 11 and the cloud imaging device 12 are physically separated.
  • the aforementioned ultrasonic probe refers to a device that can be used to transmit ultrasonic signals based on the ultrasonic control information determined by the front-end device 11 and receive ultrasonic echo signals corresponding to the transmitted ultrasonic signals.
  • the front-end device 11 is used to determine the ultrasound control information that can control the ultrasound signal emitted by the ultrasound probe, and then the ultrasound probe transmits the ultrasound signal to the target or area to be ultrasonically detected based on the ultrasound control information determined by the front-end device 11 , And receive the ultrasonic echo signal corresponding to the transmitted ultrasonic signal, the front-end device 11 generates an ultrasonic imaging signal that meets the preset conditions based on the ultrasonic echo signal received by the ultrasonic probe, and sends the generated ultrasonic echo signal to the cloud imaging device 12.
  • the cloud imaging device 12 generates ultrasound image information based on the received ultrasound imaging signal.
  • the ultrasound system provided by the embodiments of the present application simplifies the structure of the front-end device by separating the front-end device and the cloud imaging device, and integrates the function of generating ultrasound image information based on the ultrasound imaging signal into the cloud imaging device.
  • the miniaturization of the front-end device provides a prerequisite.
  • the ultrasound system provided by the embodiments of the present application integrates the function of generating ultrasound image information based on ultrasound imaging signals into the cloud imaging device, which provides convenience for the rapid upgrade and update of ultrasound imaging technology.
  • the ultrasonic probe mentioned in the above-mentioned embodiment can also be replaced by an ultrasonic transmission and recovery module (not shown in the figure) provided in the front-end device 11, which is not uniformly limited in the embodiment of the present application.
  • the signal connection between the front-end device 11 and the cloud imaging device 12 is implemented based on a network with a preset transmission speed, for example, based on a network implementation with a transmission speed greater than 125-128MB/s, so as to fully ensure cloud imaging The real-time imaging function of the device 12.
  • the signal connection between the front-end device 11 and the cloud imaging device 12 is implemented based on the 5th Generation wireless systems (5G) network.
  • 5G 5th Generation wireless systems
  • the embodiment of the present application limits the signal connection between the front-end device 11 and the cloud imaging device 12 based on 5G network implementation, which can be based on cloud imaging.
  • the device 12 achieves the purpose of real-time imaging.
  • the 5G network can support the communication connection of large-scale equipment (for example, an ultrasound system including multiple front-end devices 11), the embodiments of the present application can provide communication support for the subsequent expansion of the functional modules of the ultrasound system.
  • FIG. 2 is a schematic structural diagram of a cloud imaging device in an ultrasound system provided by an exemplary embodiment of this application.
  • the embodiment shown in FIG. 2 of this application is extended on the basis of the embodiment shown in FIG. 1 of this application. The following focuses on the differences between the embodiment shown in FIG. 2 and the embodiment shown in FIG. .
  • the ultrasound probe includes a plurality of ultrasound channels.
  • the cloud imaging device 12 includes a scheduling module 121, a data pre-processing module 122, an image reconstruction module 123 signally connected to the data pre-processing module 122, and an image post-processing module 124 signally connected to the image reconstruction module 123.
  • the scheduling module 121 is signally connected to the data pre-processing module 122, the image reconstruction module 123, and the image post-processing module 124, respectively.
  • the data pre-processing module 122 is configured to perform parallel demodulation processing operations on the ultrasound imaging signal generated by the front-end device to generate demodulation information.
  • the image reconstruction module 123 is configured to perform parallel image reconstruction operations based on the demodulated information to generate first ultrasound image information.
  • the image post-processing module 124 is used to perform image post-processing operations on the first ultrasound image information generated by the image reconstruction module 123 to generate second ultrasound image information; the scheduling module 121 is used to manage the computing nodes in the cloud imaging device 12.
  • the aforementioned image post-processing operation includes at least one of a denoising operation, a registration operation, and a recognition operation.
  • the denoising operation is implemented by the Non-Local Means algorithm
  • the registration operation is implemented by the Piecewise Rigid Motion Correction algorithm
  • the recognition operation is implemented by the Singular Value Decomposition algorithm accomplish.
  • the data pre-processing module 122, the image reconstruction module 123, and the image post-processing module 124 are all implemented using a parallel computing algorithm based on a graphics processing unit (GPU) design.
  • GPU graphics processing unit
  • the ultrasound imaging signal generated by the front-end device based on the ultrasound echo signal of the ultrasound probe is also multi-channel data.
  • the embodiment of the present application uses the aforementioned data pre-processing module 122, image reconstruction module 123, and image post-processing module 124 to achieve the purpose of processing data in parallel to increase the data processing speed of the cloud imaging device 12.
  • the data pre-processing module 122, the image reconstruction module 123, and the image post-processing module 124 are all implemented in a modular design, so as to provide extended and embedded interfaces for different algorithms, and further provide for image reconstruction operations and image post-processing modules.
  • the fast update operation of the processing operation provides guarantee.
  • the scheduling module 121 adopts a database architecture, so as to give full play to the clustering efficiency of the cloud imaging device 12, thereby improving the computing efficiency of image reconstruction and data processing.
  • the scheduling module 121 adopts a Quartz-based job scheduling framework.
  • the image post-processing module 124 can be deleted according to the actual situation, which is not uniformly limited in the embodiment of this application. .
  • FIG. 3 is a schematic structural diagram of a front-end device in an ultrasound system provided by an exemplary embodiment of this application.
  • the embodiment shown in FIG. 3 of this application is extended on the basis of the embodiment shown in FIG. 1 of this application. The following focuses on the differences between the embodiment shown in FIG. 3 and the embodiment shown in FIG. .
  • the front-end device 11 includes a beam forming module 111, an ultrasonic radio frequency data acquisition module 112 signally connected to the beam forming module 111, and an ultrasonic radio frequency data acquisition module 112 signally connected to the beam forming module 111.
  • the data compression module 113 the beam forming module 111 and the ultrasonic radio frequency data acquisition module 112 are both signally connected to the ultrasonic probe.
  • the beam forming module 111 is configured to determine ultrasound control information based on the cloud imaging device, and control the ultrasound signal emitted by the ultrasound probe based on the ultrasound control information.
  • the ultrasound control information is used to control the output of the array element of the ultrasound probe. For example, by applying excitation signals with different time delays to each array element, the focus and deflection of the ultrasonic beam output by the probe array can be controlled.
  • the embodiment of the present application can greatly facilitate the iterative upgrade operation of the ultrasound control information.
  • the unified upgrade and iterative operation of the ultrasound control information determined by the multiple front-end devices can also be realized based on the cloud imaging device, thereby quickly realizing standardized control of ultrasound imaging and breaking The situation that ultrasound equipment of different manufacturers cannot be managed uniformly has facilitated the communication and sharing of clinical diagnosis.
  • the ultrasound radio frequency data acquisition module 112 is used to convert the ultrasound echo signals recovered by the ultrasound probe into ultrasound imaging signals that meet preset conditions.
  • the data compression module 113 is used to perform parallel data compression operations on the ultrasound imaging signal, so as to better achieve the purpose of real-time imaging.
  • the data compression module 113 in the embodiment of the present application can reduce the data transmission pressure, thereby ensuring the real-time imaging function of the ultrasound system.
  • the ultrasound system mentioned in the embodiments of the present application uses the beam forming module, the ultrasound radio frequency data acquisition module and the data compression module, as well as the signal connection relationship between the modules, to form the ultrasound system used to determine the ultrasound signal emitted by the ultrasound probe.
  • a front-end device that controls information and generates an ultrasound imaging signal that meets preset conditions based on the ultrasound echo signal corresponding to the ultrasound signal.
  • the front-end device mentioned in the embodiment of the present application implements the above-mentioned functions based on the above-mentioned layout structure, and has many advantages such as reasonable layout, low cost, and strong practicability.
  • the ultrasound probe includes a plurality of array elements
  • the beam forming module 111 includes a dual-port random access memory (RAM), and the dual-port random access memory is used to control the plurality of array elements
  • RAM dual-port random access memory
  • the output information in order to form the spatial directivity of the beam, so that the ultrasonic probe emits a plane wave with a preset deflection angle.
  • the beam forming module 111 is based on RAM and according to a preset deflection angle, calculates the delay time of each element and records it in the RAM.
  • the pulse generator in the beamforming module 111 applies excitation signals to the corresponding element at different times, and the delay time of all the elements is linearly arranged with a preset deflection angle to drive the element
  • the array emits a plane wave including a preset deflection angle.
  • the embodiment of the present application Unlike the existing focused beam imaging that requires linear focus scanning, and then superimposes the results of multiple scans to obtain a two-dimensional image, the embodiment of the present application only needs to emit a plane wave once to excite a full-field signal to obtain a frame of two-dimensional image. Therefore, the embodiment of the present application greatly improves the imaging speed, and achieves the purpose of ultra-fast imaging.
  • the data compression module 113 can be deleted according to the actual situation, which is not uniformly limited in the embodiment of the present application.
  • FIG. 4 is a schematic structural diagram of an ultrasound system provided by another exemplary embodiment of this application.
  • the embodiment shown in Fig. 4 of this application is extended on the basis of the embodiment shown in Figs. 1 to 3 of the present application.
  • the following focuses on the differences between the embodiment shown in Fig. 4 and the embodiment shown in Figs. 1 to 3 , The similarities will not be repeated.
  • the ultrasound system 10 provided in the embodiment of the present application further includes an ultrasound display device 14 signally connected to the cloud imaging device 12.
  • the ultrasonic display device 14 includes a communication module 141 and an image display module 142 signally connected to the communication module 141.
  • the communication module 141 is signally connected to the image post-processing module 124 of the cloud imaging device 12 to transmit the second ultrasound image information generated by the image post-processing module 124 to the image display module 142.
  • the image display module 142 is configured to display an ultrasound image based on the received second ultrasound image information for the user to view.
  • the front-end device 11 further includes a data communication module 114, and the data communication module 114 is signally connected to the data compression module 113 and the scheduling module 121 in the cloud imaging device 12, respectively.
  • the data communication module 114 is used to establish a signal connection relationship between the front-end device 11 and the cloud imaging device 12 so as to transmit the ultrasound imaging signal generated by the front-end device 11 to the cloud imaging device 12.
  • the signal connection between the ultrasonic probe 13 and the beamforming module 111 and the ultrasonic radio frequency data acquisition module 112 in the front-end device 11 is implemented based on a cable. That is, the signal connection between the ultrasonic probe 13 and the front-end device 11 is realized based on a cable method.
  • the ultrasonic probe 13 and the front-end device 11 are local devices that are placed together in the preset ultrasonic testing space, the signal connection between the two is limited to be based on cable, which not only fully guarantees the real-time and stable data transmission Performance, and can effectively reduce costs.
  • the signal connection between the front-end device 11 and the cloud imaging device 12 is based on a network with a preset transmission speed
  • the signal connection between the cloud imaging device 12 and the ultrasound display device 14 is based on a network with a preset transmission speed
  • a 5G network implemented wirelessly.
  • the image display module 142 in the ultrasonic display device 14 may be a display device with a network connection function alone, or may be a display module of an existing ultrasonic diagnostic apparatus, which is not uniformly limited in the embodiment of the present application.
  • the ultrasound system provided by the embodiments of the present application utilizes an ultrasound probe, a front-end device, a cloud imaging device, an ultrasound display device, and the signal connection relationship between the devices to form an ultrasound system capable of real-time ultrasound imaging with the aid of the cloud imaging device.
  • the ultrasound system mentioned in the embodiments of this application not only realizes the lightweight of front-end equipment (such as ultrasound probes and front-end devices), and facilitates the use of users, but also provides rapid upgrade and update of post-processing equipment (such as cloud imaging devices) condition.
  • the ultrasound probe includes multiple ultrasound channels
  • the data compression module 113 includes multiple compression units
  • the ultrasound radio frequency data acquisition module 112 is connected to each of the multiple ultrasound channels correspondingly, and uses multiple analog-to-digital conversion (A/D) to convert the respective original radio frequency analog signals corresponding to the multiple ultrasound channels into parallel Then, the converted parallel digital signals are respectively transmitted to the corresponding compression unit, and the parallel data compression operation is performed to reduce the amount of transmitted data.
  • A/D analog-to-digital conversion
  • the ultrasonic radio frequency data acquisition module 112 is implemented based on a dual-input 7-13-bit incremental analog-to-digital converter of Cypress Semiconductor.
  • the data compression module 113 is implemented using a Huffman coding compression algorithm.
  • the data communication module 114 is implemented based on a wireless parallel gateway module.
  • the parallel gateway module performs parallel transmission and reception of data transmission and reception operations, and the data entering the gateway is divided into multiple channels according to the radio frequency data channel, and thus is wirelessly transmitted to the cloud imaging device 12.
  • the image reconstruction method adopted by the image reconstruction module 123 is a parallel delay and sum (DAS) method or a parallel frequency-wavenumber migration f-K method.
  • DAS parallel delay and sum
  • the image reconstruction module 123 adopts a parallel frequency-wavenumber migration fk method to perform image reconstruction.
  • the specific calculation process is: suppose the x direction is the parallel direction of the ultrasonic transducer array, the z direction is the depth direction of the imaging medium, and ⁇ (x,z,t) is the scalar field that satisfies the linear wave equation.
  • First, perform Fourier transform on ⁇ (x,z 0,t) in the (x,t) direction to obtain ⁇ (k x , ⁇ ).
  • the image results obtained under different deflection angles are subjected to a coherent superposition operation.
  • a frame of image obtained by a single plane wave is s( ⁇ , x, z).
  • an output image s( ⁇ i ,x,z) can be obtained, and then The final plane wave composite image can be obtained by superimposing the N output images:
  • the time sliding window mode is used for coherent plane wave composite at N angles, that is, the current frame obtained from each reconstruction is coherently composited with the previous N-1 frames, and the window is sequentially slid to perform coherent composite at N angles.
  • the transmitted deflection angle sequence is ⁇ 1 , ⁇ 2 ,... ⁇ N , ⁇ 1 , ⁇ 2 ,... ⁇ N , ⁇ 1 , ⁇ 2 ,... ⁇ N ,...
  • the corresponding output image is s j ( ⁇ i ,x,z)
  • the plane wave composite image obtained at time t is the current output image and the previous N-1 frames for multi-angle coherent composite, and Sliding window, namely
  • the choice of N value is 4 to 32, and the choice of N depends on the requirements for image reconstruction quality and image reconstruction speed.
  • the value of N is 9 in order to achieve a balance between image reconstruction quality and image reconstruction speed.
  • Algorithms embedded in the cloud imaging device 12 can be flexibly changed and set according to actual conditions to enrich methods such as image post-processing, thereby forming the aforementioned distributed ultrasound imaging system.

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Abstract

Système à ultrasons (10), qui comprend un dispositif d'extrémité avant (11) et un dispositif d'imagerie en nuage (12) en connexion de signal avec le dispositif d'extrémité avant (11). Le dispositif d'extrémité avant (11) est utilisé pour déterminer des informations de commande d'ultrasons qui peuvent commander un signal ultrasonore émis par une sonde ultrasonore (13), et sur la base d'un signal d'écho ultrasonore correspondant au signal ultrasonore, générer un signal d'imagerie ultrasonore qui satisfait une condition prédéfinie. Le dispositif d'imagerie en nuage (12) est utilisé pour générer des informations d'image ultrasonore sur la base du signal d'imagerie ultrasonore. Le système à ultrasons (10) simplifie la structure du dispositif d'extrémité avant (11) en séparant le dispositif d'extrémité avant (11) et le dispositif d'imagerie en nuage (12) et en intégrant dans le dispositif d'imagerie en nuage (12) la fonction de génération d'informations d'image ultrasonore sur la base du signal d'imagerie ultrasonore, fournissant ainsi un prérequis à la miniaturisation du dispositif d'extrémité avant (11). En outre, en intégrant dans le dispositif d'imagerie en nuage (12) la fonction de génération d'informations d'image ultrasonore sur la base du signal d'imagerie ultrasonore, le système à ultrasons (10) fournit une commodité de mise à niveau et de mise à jour rapides de la technologie d'imagerie ultrasonore.
PCT/CN2021/085688 2020-04-15 2021-04-06 Système à ultrasons WO2021208776A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CN202010295631.6A CN111345849A (zh) 2020-04-15 2020-04-15 超声系统
CN202010295631.6 2020-04-15
CN202020560711.5U CN212346569U (zh) 2020-04-15 2020-04-15 超声系统
CN202020560711.5 2020-04-15

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