WO2021207698A1 - Dispositifs de réduction de saignement et leurs procédés de fabrication et d'utilisation - Google Patents

Dispositifs de réduction de saignement et leurs procédés de fabrication et d'utilisation Download PDF

Info

Publication number
WO2021207698A1
WO2021207698A1 PCT/US2021/026714 US2021026714W WO2021207698A1 WO 2021207698 A1 WO2021207698 A1 WO 2021207698A1 US 2021026714 W US2021026714 W US 2021026714W WO 2021207698 A1 WO2021207698 A1 WO 2021207698A1
Authority
WO
WIPO (PCT)
Prior art keywords
ampule
medication
wound
reservoir
topical applicator
Prior art date
Application number
PCT/US2021/026714
Other languages
English (en)
Inventor
Anton Travis MANASCO
Christopher J. DUNATOV
Nicholas Joseph JARDINE
Original Assignee
Alacrity Medical Innovations, Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alacrity Medical Innovations, Llc filed Critical Alacrity Medical Innovations, Llc
Priority to JP2022561623A priority Critical patent/JP2023521142A/ja
Priority to CA3179861A priority patent/CA3179861A1/fr
Priority to EP21785331.6A priority patent/EP4132630A4/fr
Priority to CN202180037288.8A priority patent/CN115988997A/zh
Priority to AU2021254290A priority patent/AU2021254290A1/en
Priority to PCT/US2021/053641 priority patent/WO2022076467A1/fr
Priority to EP21878399.1A priority patent/EP4225421A1/fr
Priority to JP2023518768A priority patent/JP2023545645A/ja
Priority to KR1020237014925A priority patent/KR20230098185A/ko
Priority to CN202180074080.3A priority patent/CN116490134A/zh
Priority to AU2021358758A priority patent/AU2021358758A1/en
Priority to CA3193893A priority patent/CA3193893A1/fr
Publication of WO2021207698A1 publication Critical patent/WO2021207698A1/fr
Priority to US17/522,736 priority patent/US11654057B2/en
Priority to US17/728,894 priority patent/US11622893B2/en
Priority to US18/186,716 priority patent/US20230329915A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M35/00—Devices for applying media, e.g. remedies, on the human body
    • A61M35/003—Portable hand-held applicators having means for dispensing or spreading integral media
    • A61M35/006—Portable hand-held applicators having means for dispensing or spreading integral media using sponges, foams, absorbent pads or swabs as spreading means

Definitions

  • the present invention relates generally to devices having topical applicators, and more specifically to devices having topical applicators for reducing bleeding of a wound and/or achieving hemostasis at a wound.
  • FIG. 5 is a cut-away view of a device according to embodiments of the present invention, in which the device comprises a reservoir, ampule, release mechanism, and topical applicator; and in which the release mechanism is at the wall of the reservoir.
  • the ampule comprises a glass ampule.
  • the ampule 130 may comprise a metered dose of the medication 132 ranging from about 1 mL to about 20 mL, or about 1 ml, to about 1.5 mL, or about 2,5 ml, to about 5 mL, or about 5 mL to about 10 ml,, or about 10 mL to about 15 mL, or about 15 mL to about 20 mL.
  • the topical applicator ISO is attached to the reservoir via a fixation plate 160, as shown in FIGS. 1, 4, and 6.
  • the fixation plate 160 is attached to the closed end of the reservoir via an adhesive or welding, and creates a seal to ensure that the medication 132 is directed to the topical applicator ISO.
  • the fixation plate 160 comprises an opening (not shown) through which the medication 132 can contact the topical applicator 150.

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Road Signs Or Road Markings (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)

Abstract

Un dispositif qui comprend un réservoir, une ampoule à l'intérieur du réservoir contenant un médicament, un mécanisme de libération accouplé mécaniquement à l'ampoule, et un applicateur topique fixé au réservoir. Le mécanisme de libération est conçu pour, lors de l'activation, appliquer une force mécanique qui provoque la rupture de l'ampoule et la libération du médicament. Le médicament libéré peut être retenu par l'applicateur topique et administré sur une plaie. Le médicament peut comprendre de l'acide tranexamique. Le dispositif peut être utilisé pour traiter une plaie et réduire le saignement d'une plaie.
PCT/US2021/026714 2020-04-09 2021-04-09 Dispositifs de réduction de saignement et leurs procédés de fabrication et d'utilisation WO2021207698A1 (fr)

Priority Applications (15)

Application Number Priority Date Filing Date Title
JP2022561623A JP2023521142A (ja) 2020-04-09 2021-04-09 出血低減のためのデバイス並びにそれを作製及び使用する方法
CA3179861A CA3179861A1 (fr) 2020-04-09 2021-04-09 Dispositifs de reduction de saignement et leurs procedes de fabrication et d'utilisation
EP21785331.6A EP4132630A4 (fr) 2020-04-09 2021-04-09 Dispositifs de réduction de saignement et leurs procédés de fabrication et d'utilisation
CN202180037288.8A CN115988997A (zh) 2020-04-09 2021-04-09 用于减少出血的设备及其制造方法和使用方法
AU2021254290A AU2021254290A1 (en) 2020-04-09 2021-04-09 Devices for bleeding reduction and methods of making and using the same
JP2023518768A JP2023545645A (ja) 2020-10-05 2021-10-05 出血を減らすためのデバイス及びそのデバイスを製造及び使用する方法
EP21878399.1A EP4225421A1 (fr) 2020-10-05 2021-10-05 Dispositifs de réduction de saignement et leurs procédés de fabrication et d'utilisation
PCT/US2021/053641 WO2022076467A1 (fr) 2020-10-05 2021-10-05 Dispositifs de réduction de saignement et leurs procédés de fabrication et d'utilisation
KR1020237014925A KR20230098185A (ko) 2020-10-05 2021-10-05 출혈 감소를 위한 장치 및 그 제조 및 사용 방법
CN202180074080.3A CN116490134A (zh) 2020-10-05 2021-10-05 用于减少出血的装置及其制作和使用方法
AU2021358758A AU2021358758A1 (en) 2020-10-05 2021-10-05 Devices for bleeding reduction and methods of making and using the same
CA3193893A CA3193893A1 (fr) 2020-10-05 2021-10-05 Dispositifs de reduction de saignement et leurs procedes de fabrication et d'utilisation
US17/522,736 US11654057B2 (en) 2020-04-09 2021-11-09 Devices for bleeding reduction and methods of making and using the same
US17/728,894 US11622893B2 (en) 2020-04-09 2022-04-25 Devices for bleeding reduction and methods of making and using the same
US18/186,716 US20230329915A1 (en) 2020-04-09 2023-03-20 Devices for bleeding reduction and methods of making and using the same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063007543P 2020-04-09 2020-04-09
US63/007,543 2020-04-09

Related Child Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2021/053641 Continuation-In-Part WO2022076467A1 (fr) 2020-04-09 2021-10-05 Dispositifs de réduction de saignement et leurs procédés de fabrication et d'utilisation

Publications (1)

Publication Number Publication Date
WO2021207698A1 true WO2021207698A1 (fr) 2021-10-14

Family

ID=78024157

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2021/026714 WO2021207698A1 (fr) 2020-04-09 2021-04-09 Dispositifs de réduction de saignement et leurs procédés de fabrication et d'utilisation

Country Status (6)

Country Link
EP (1) EP4132630A4 (fr)
JP (1) JP2023521142A (fr)
CN (1) CN115988997A (fr)
AU (1) AU2021254290A1 (fr)
CA (1) CA3179861A1 (fr)
WO (1) WO2021207698A1 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022076467A1 (fr) * 2020-10-05 2022-04-14 Bio 54, Llc Dispositifs de réduction de saignement et leurs procédés de fabrication et d'utilisation
US11622893B2 (en) 2020-04-09 2023-04-11 Bio 54, Llc Devices for bleeding reduction and methods of making and using the same
US11642324B1 (en) 2022-03-01 2023-05-09 Bio 54, Llc Topical tranexamic acid compositions and methods of use thereof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5288159A (en) * 1992-12-04 1994-02-22 Minnesota Mining And Manufacturing Company Liquid applicator with frangible ampoule and support
US20050054967A1 (en) * 2003-09-05 2005-03-10 Gary Ashe Fome swab applicator for fluid-containing ampule
US6991394B2 (en) * 2003-01-10 2006-01-31 Medi-Flex, Inc. Liquid applicator with a mechanism for fracturing multiple ampoules
JP5128837B2 (ja) * 2006-03-24 2013-01-23 タイコ ヘルスケア グループ リミテッド パートナーシップ 環状接着構造体
US10478851B2 (en) * 2015-05-29 2019-11-19 Sulzer Mixpac Ag Applicator for a fluid ingredient and method of activating an applicator

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020076255A1 (en) * 2000-12-20 2002-06-20 Hoang Minh Q. Skin disinfectant applicator
US11160962B2 (en) * 2017-05-16 2021-11-02 Professional Disposables International, Inc. Antiseptic delivery device and method of use
US20210322742A1 (en) * 2018-08-21 2021-10-21 3M Innovative Properties Company Flexible applicator handle region

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5288159A (en) * 1992-12-04 1994-02-22 Minnesota Mining And Manufacturing Company Liquid applicator with frangible ampoule and support
US6991394B2 (en) * 2003-01-10 2006-01-31 Medi-Flex, Inc. Liquid applicator with a mechanism for fracturing multiple ampoules
US20050054967A1 (en) * 2003-09-05 2005-03-10 Gary Ashe Fome swab applicator for fluid-containing ampule
JP5128837B2 (ja) * 2006-03-24 2013-01-23 タイコ ヘルスケア グループ リミテッド パートナーシップ 環状接着構造体
US10478851B2 (en) * 2015-05-29 2019-11-19 Sulzer Mixpac Ag Applicator for a fluid ingredient and method of activating an applicator

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP4132630A4 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11622893B2 (en) 2020-04-09 2023-04-11 Bio 54, Llc Devices for bleeding reduction and methods of making and using the same
WO2022076467A1 (fr) * 2020-10-05 2022-04-14 Bio 54, Llc Dispositifs de réduction de saignement et leurs procédés de fabrication et d'utilisation
US11642324B1 (en) 2022-03-01 2023-05-09 Bio 54, Llc Topical tranexamic acid compositions and methods of use thereof

Also Published As

Publication number Publication date
AU2021254290A1 (en) 2022-11-03
CA3179861A1 (fr) 2021-10-14
EP4132630A4 (fr) 2024-06-05
JP2023521142A (ja) 2023-05-23
CN115988997A (zh) 2023-04-18
EP4132630A1 (fr) 2023-02-15

Similar Documents

Publication Publication Date Title
WO2021207698A1 (fr) Dispositifs de réduction de saignement et leurs procédés de fabrication et d'utilisation
Bruns et al. A new tissue adhesive for laceration repair in children
US20230329915A1 (en) Devices for bleeding reduction and methods of making and using the same
US5466465A (en) Transdermal drug delivery system
US8956065B2 (en) Applicator for dispensing a surgical prep solution
US20160030368A1 (en) Sinus anesthesia kit
Howell et al. Outpatient wound preparation and care: a national survey
WO2018185555A2 (fr) Systèmes, appareils, kits et méthodes pour des actes médicaux améliorés
US20110257610A1 (en) Therapeutic Diffusion Wound Dressing and Filling Method
US20080139988A1 (en) Bandage, topical agent-bearing package and topical agent-bearing element
US20160287814A1 (en) Medical illumination device
KR20220031641A (ko) 방출가능 항미생물제로 충전된 절개 드레이프를 포함하는 수술 부위 감염을 감소시키기 위한 상처 봉합 시스템
Gupta et al. Application of autologous platelet-rich plasma to graft donor sites to reduce pain and promote healing
CA3193893A1 (fr) Dispositifs de reduction de saignement et leurs procedes de fabrication et d'utilisation
WO2022076467A1 (fr) Dispositifs de réduction de saignement et leurs procédés de fabrication et d'utilisation
AU2021358758A9 (en) Devices for bleeding reduction and methods of making and using the same
CN116490134A (zh) 用于减少出血的装置及其制作和使用方法
US20220280443A1 (en) Transdermal Delivery System
Broman et al. Emergency equipment on the field
Yan et al. Equipment and supplies for sports and event medicine
US8690841B2 (en) Wound care system
Fantl Wound Care and Dressing Changes
Jackimczyk et al. Management of pediatric wounds
Cowan Wound Series Part 2: Introduction to Chronic Wound Treatments
Hill et al. Marine Corps Operational Medicine: Determining Medical Supply Needs of the Surgical Company Ward, Lab, and Pharmacy

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 21785331

Country of ref document: EP

Kind code of ref document: A1

ENP Entry into the national phase

Ref document number: 2022561623

Country of ref document: JP

Kind code of ref document: A

ENP Entry into the national phase

Ref document number: 3179861

Country of ref document: CA

ENP Entry into the national phase

Ref document number: 2021254290

Country of ref document: AU

Date of ref document: 20210409

Kind code of ref document: A

NENP Non-entry into the national phase

Ref country code: DE

ENP Entry into the national phase

Ref document number: 2021785331

Country of ref document: EP

Effective date: 20221109