WO2021151184A1 - Stimulating beverage - Google Patents

Stimulating beverage Download PDF

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Publication number
WO2021151184A1
WO2021151184A1 PCT/BR2021/050041 BR2021050041W WO2021151184A1 WO 2021151184 A1 WO2021151184 A1 WO 2021151184A1 BR 2021050041 W BR2021050041 W BR 2021050041W WO 2021151184 A1 WO2021151184 A1 WO 2021151184A1
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WIPO (PCT)
Prior art keywords
nicotine
configuration
carbon dioxide
water
tobacco
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PCT/BR2021/050041
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French (fr)
Portuguese (pt)
Inventor
Bruno Ghizoni Da Silva
Original Assignee
Bruno Ghizoni Da Silva
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Publication of WO2021151184A1 publication Critical patent/WO2021151184A1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/38—Other non-alcoholic beverages
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52—Adding ingredients
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52—Adding ingredients
    • A23L2/54—Mixing with gases
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Definitions

  • the present patent application proposes a new formulation of a stimulating drink which can be intended for consumption in general, but is particularly aimed at the public that wants to stay awake to study or work.
  • the social function of innovation is to generate a healthy alternative that allows people to stay awake with quality.
  • the object proposed by the present patent application describes a new type of stimulant drink, which innovates by providing for the unprecedented use of nicotine as a stimulant element.
  • stimulant beverages classified as energy drinks are non-alcoholic beverages with combinations of ingredients that commonly include caffeine, taurine, vitamins, as well as other substances such as glucuronolactone, flavoring and coloring.
  • Energy drinks are available in a variety of formulas and are offered in a wide variety of flavors and in sugar-free and sugar-free versions. Regularly, a 250ml energy drink can contains up to 80mg of caffeine, which is equivalent, for example, to the amount of the substance present in a cup of espresso coffee.
  • the energy drinks market is considered one of the largest in the world, with the Brazilian market alone moving around R$ 1.5 billion per year. In 2015 alone, it is estimated that more than 390 million cans were consumed in the country.
  • Caffeine is found naturally in many plants, such as coffee beans, tea leaves, cocoa beans, kola nuts, guarana plants and yerba mate. It can also be produced synthetically, with no chemical differences between its versions.
  • Figure 1, which integrates this patent application, represents a graph illustrating the amount of caffeine present in various types of beverage, and it should be noted that the parameter for attributing limits to caffeine consumption is based on body weight and not on age.
  • Taurine is an amino acid that is present in the daily diet and can be consumed naturally in foods such as seafood and poultry.
  • the taurine present in the energy drink is synthetically produced and has exactly the same characteristics and properties as the taurine produced by the body. Taurine plays an important role in several physiological functions, acting in osmotic regulation, immune function, glucose metabolism, as well as neurological and retinal development.
  • Energizers provide greater physical disposition, thanks to the effects of the caffeine present in the drink.
  • the B-complex vitamins present in most energy drinks also contribute to the reduction of tiredness and fatigue.
  • Synthetically manufactured ingredients guarantee high quality, as they are produced in accordance with the technical and regulatory requirements of each location and perform the same function as their natural counterparts.
  • the taurine present in the energy drink is synthetically produced and has exactly the same characteristics and properties as the taurine produced by the body. Most energy drinks contain the same amount or even less caffeine than a cup of coffee.
  • Nicotine is a nitrogen-containing chemical that is made by many types of plants, including the tobacco plant. It is also produced synthetically. Nicotiana tabacum, the type of nicotine found in tobacco plants, comes from the nightshade family. Peppers, eggplants, tomatoes and potatoes are examples of the nightshade family.
  • the tobacco plant originates from the Americas and has been used as a medicine and stimulant for at least 2,000 years. Its name comes from the French diplomat Jean Nicot, who was the tobacco diffuser in France. French ambassador in Lisbon, Jean Nicot brought this plant from Portugal and made it known in his country.
  • tobacco is different from nicotine.
  • Tobacco addiction is caused by an increase in dopamine in the brain's reward circuits as with other addictive drugs.
  • MAO monoamine oxidase
  • NRT - Nicotine Replacement Therapy Many people who want to quit smoking use nicotine gum, gum and patches in doses equivalent to those consumed by smokers (this procedure is called NRT - Nicotine Replacement Therapy).
  • the tablets, chewing gum and adhesives are sold in physical pharmacies and over the internet without the need for a prescription.
  • Cigarette A cigarette contains up to 2mg of nicotine.
  • a light cigarette has from 0.6mg to 1mg.
  • a regular cigarette has 1.2 mg - 1.4 mg.
  • a person who smokes a pack of cigarettes a day can consume 24mg of nicotine.
  • Chewing Gum Nicotine chewing gum has about 2mg to 4mg of nicotine.
  • Nicotine Patch A nicotine patch contains 15mg to 30mg of nicotine.
  • An electronic cigarette can contain up to 41 mg of nicotine
  • RDC products n. 46, of August 28, 2009, art. 1 o ANVISA records its understanding of what a tobacco product is and classifies them into three types: Burnt tobacco products/fuels; Smokeless tobacco products; Heated/Steamed Tobacco Products.
  • Cigarette are the best known product in Brazil and can be composed in four ways: tobacco wrapped in paper; homogenized tobacco or reconstituted; a mixture of cellulose and tobacco; other wrap that is not exclusively tobacco leaf.
  • Cigar The cigar is composed of whole tobacco leaves, chopped, shredded or broken, rolled into a cylinder, with a wrapper consisting of tobacco leaf or reconstituted tobacco.
  • Cigarillo The cigarillo is characterized by weighing less than 1,360 g/1,000 cigarillos. It is composed of tobacco leaves, chopped, shredded, powdered or broken, forming a cylinder, and its wrapping is constituted by tobacco leaf or reconstituted tobacco.
  • Shredded tobacco is composed of shredded tobacco leaves and may or may not be processed by the industry, allowing the user to roll their cigarette.
  • Coil smoke Coil tobacco, also called rope tobacco, is made from peeled, intertwined, and rolled tobacco leaves that have undergone a sun-curing process.
  • Pipe The pipe requires a smoke intended for its use, called pipe tobacco
  • the kretek cigarette popularly known as clove cigarette or bali cigarette, is a mixture of 60% to 80% tobacco and 40% to 20% clove. It can be wrapped in paper, homogenized or reconstituted tobacco, a mixture of cellulose and tobacco, or other wrapping.
  • Straw cigarette is also one of the unfiltered products. Its composition is simple: chopped tobacco wrapped in corn husks.
  • Bidi has no filter and is made from a small portion of shredded tobacco wrapped in leaves of tendu or temburi, plants native to Asia.
  • Blunt is considered a derivative of tobacco because it is present in its composition. Unlike the other products presented, it is a wrapper used to place tobacco inside (for example, shredded tobacco) with the purpose of being smoked.
  • Inhalable tobacco also known as snuff, is one of the tobacco products that does not generate smoke due to being inhaled.
  • Snus With a different name, Snus, very common in Sweden, is made up of moist, powdered tobacco for oral use.
  • Chewing tobacco or chewable tobacco, is one of the smokeless tobacco products used to be chewed or sucked.
  • hookah smoking Hubble, pipe of water, or hookah shisha: the same device has several names, and all refer to equipment which is used for hookah smoking with - other tobacco product.
  • the hookah pipe contains a container called a bowl, which stores the tobacco. This can come into contact with the burning charcoal and, therefore, burn organic matter.
  • the classification of hookah smoke as a heated/vaporized tobacco product may not cover all possible emissions during its use.
  • Electronic smoking devices are also known as electronic hookahs, electronic cigarettes, e-cigarettes, e-ciggy, ecigar, among others, which can have different forms, but with the common objective of simulating the use of tobacco products such as cigarettes, cigarillos, cigars, pipes and the like. These electronic devices vaporize a cartridge or container that contains tobacco leaf extract. They can also use the liquid purchased individually and contain nicotine or not.
  • Law No. 10.167, of December 27, 2000 amended Law No. 9,294/1996, including the prohibition of commercial advertising of tobacco products in newspapers, magazines, television, internet, sponsorship of cultural or sports activities , and only allowed advertising through posters, panels and posters inside the place where the product was sold.
  • RDC No. 15, of January 17, 2003 established the definitions for commercial advertising of tobacco products, internal parts of sales outlets and prohibited the sale and offer of products on the internet.
  • RDC No. 335/2003 also regulated the printing of health warning images and phrases in advertising materials for tobacco-derived smoking products.
  • Nicotine induces the release of the neurotransmitter glutamate, an excitatory neurotransmitter involved in synaptic plasticity, which is one of the possible causes for the effect of nicotine to be considered a substance that aids memory (although not in the form of tobacco, this is a reducer of cerebral oxygenation ).
  • the doctor of neurology also claims that nicotine modulates other neurotransmitter systems. That is, if we are sleepy, nicotine wakes up, and if we are anxious, nicotine relaxes. Dr. Ricardo also informs that the suspension of the use of nicotine patches does not cause withdrawal and there is no tendency to abuse.
  • figure 1 represents a graphic showing the amount of caffeine present in various types of beverage, having as source the EFSA - European Authority of Food Safety.
  • the present patent application proposes a stimulant drink that contains nicotine with the objective of helping people to stay awake with quality and in a healthy way.
  • the drink can be classified as energetic.
  • a drink can be considered energetic if its central ingredients are one or more of these substances: inositol, glucuronolactone, taurine and caffeine.
  • the drink in question is primarily formed by water, nicotine, sugar, taurine, glucuronalactone, caffeine and inositol which are formulated in water and carbon dioxide. Additionally, supporting ingredients commonly found in carbonated beverages are present in the formation, such as acidulant, antioxidant, acidity regulator, sodium citrate, flavoring, colorant, preservative, potassium sorbate, sweeteners and neotame.
  • the formulation in question may have different central configurations, with emphasis on:

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Abstract

The present invention patent application proposes a stimulating beverage formulation including nicotine as an active substance, that is intended for general consumption, and more specifically aimed at consumers wishing to stay awake to study or work. The social function of the innovation comprises providing a healthy alternative that enables people to stay awake productively. The main formulation of the stimulating beverage proposed herein is as follows: taurine (10 mg to 400 mg/100 ml), nicotine (0.1 mg to 40 mg/100 ml), glucuronolactone (10 mg to 300 mg/100 ml), caffeine (3 mg to 40 mg/100 ml), inositol (from 1 mg to 20 mg/100 ml), sugars (7 g to 33 g/100 ml), water (269 ml or according to product configuration), and carbon dioxide.

Description

“BEBIDA ESTIMULANTE” "STIMULATING DRINK"
CAMPO DE APLICAÇÃO APPLICATION FIELD
O presente pedido de Patente de Invenção propõe uma nova formulação de bebida estimulante a qual pode ser destinada ao consumo em geral, mas é particularmente voltada ao público que deseja ficar desperto para estudar ou trabalhar. A função social da inovação consiste em gerar uma alternativa saudável e que permita que as pessoas fiquem acordadas com qualidade. The present patent application proposes a new formulation of a stimulating drink which can be intended for consumption in general, but is particularly aimed at the public that wants to stay awake to study or work. The social function of innovation is to generate a healthy alternative that allows people to stay awake with quality.
PREÂMBULO PREAMBLE
O objeto proposto pelo presente pedido de Patente de Invenção descreve um novo tipo de bebida estimulante, a qual inova pelo fato de prever o inédito emprego de nicotina como elemento estimulante. The object proposed by the present patent application describes a new type of stimulant drink, which innovates by providing for the unprecedented use of nicotine as a stimulant element.
ESTADO DA TÉCNICA: TECHNICAL STATUS:
Segundo a ABIR, Associação Brasileira das Indústrias de Refrigerantes e de bebidas não alcóolicas, as bebidas estimulantes classificadas como energéticos são bebidas não alcoólicas com combinações de ingredientes que comumente incluem cafeína, taurina, vitaminas, bem como outras substâncias como glucuronolactona, aromatizantes e corantes. According to ABIR, the Brazilian Association of Soft Drinks and Non-Alcoholic Beverages Industries, stimulant beverages classified as energy drinks are non-alcoholic beverages with combinations of ingredients that commonly include caffeine, taurine, vitamins, as well as other substances such as glucuronolactone, flavoring and coloring.
As bebidas energéticas estão disponíveis em várias fórmulas e são oferecidas em uma variedade ampla de sabores e em versões com ou sem açúcar. Regularmente, uma lata de bebida energética de 250ml contém até 80mg de cafeína, o que é equivalente, por exemplo, à quantidade da substância presente em uma xícara de café expresso. Energy drinks are available in a variety of formulas and are offered in a wide variety of flavors and in sugar-free and sugar-free versions. Regularly, a 250ml energy drink can contains up to 80mg of caffeine, which is equivalent, for example, to the amount of the substance present in a cup of espresso coffee.
O mercado de bebidas energéticas é considerado um dos maiores do mundo, sendo que somente o mercado brasileiro movimenta cerca de R$ 1 ,5 bilhões por ano. Apenas em 2015, estima-se que foram consumidas no país mais de 390 milhões de latas. The energy drinks market is considered one of the largest in the world, with the Brazilian market alone moving around R$ 1.5 billion per year. In 2015 alone, it is estimated that more than 390 million cans were consumed in the country.
Dados da consultoria Euromonitor revelam que a categoria de energéticos é a que mais cresce no setor. Enquanto o mercado de bebidas não alcoólicas cresceu globalmente na faixa dos 4% nos últimos cinco anos, as bebidas energéticas apresentaram taxa média de crescimento de 13%, com destaque para os países emergentes. Data from the consultancy Euromonitor reveal that the category of energy drinks is the fastest growing in the sector. While the market for non-alcoholic beverages has grown globally in the range of 4% in the last five years, energy drinks had an average growth rate of 13%, with an emphasis on emerging countries.
Na questão de regulamentação, no Brasil, as bebidas energéticas são regulamentadas pela ANVISA em Resolução especifica que trata de “Compostos Líquidos Prontos para o Consumo”. Primando pela segurança do produto e respaldada por pesquisas e padrões internacionais, a regulamentação nacional estabelece limites referentes às quantidades de cafeína e taurina, quais sejam 350mg/L e 400mg/100ml bem como avisos sobre o consumo de bebidas energéticas por grupos específicos que podem ser eventualmente mais sensíveis ao consumo de cafeína. In the matter of regulation, in Brazil, energy drinks are regulated by ANVISA in a specific Resolution that deals with “Ready-to-Drink Liquid Compounds”. Striving for product safety and backed by international research and standards, national regulations establish limits on the amounts of caffeine and taurine, which are 350mg/L and 400mg/100ml, as well as warnings about the consumption of energy drinks by specific groups that may be possibly more sensitive to caffeine consumption.
A cafeína é encontrada naturalmente em muitas plantas, como grãos de café, folhas de chá, grãos de cacau, nozes de cola, plantas de guaraná e erva-mate. Ela também pode ser produzida de maneira sintética, não havendo qualquer diferença química entre suas versões. A figura 1 que integra o presente pedido de Patente de Invenção representa um gráfico ilustrativo da quantidade de cafeína presente em diversos tipos de bebida, devendo ser ressaltado que o parâmetro para atribuição de limites ao consumo de cafeína tem como referência o peso corporal e não a idade. Caffeine is found naturally in many plants, such as coffee beans, tea leaves, cocoa beans, kola nuts, guarana plants and yerba mate. It can also be produced synthetically, with no chemical differences between its versions. Figure 1, which integrates this patent application, represents a graph illustrating the amount of caffeine present in various types of beverage, and it should be noted that the parameter for attributing limits to caffeine consumption is based on body weight and not on age.
A taurina é um aminoácido que está presente na dieta diária e pode ser consumida naturalmente em alimentos como frutos do mar e carnes de aves. A taurina presente no energético é produzida sinteticamente e tem exatamente as mesmas características e propriedades da taurina produzida pelo corpo. A taurina desempenha papel importante em diversas funções fisiológicas, atuando na regulação osmótica, função imunológica, no metabolismo de glicose, bem como no desenvolvimento neurológico e da retina. Taurine is an amino acid that is present in the daily diet and can be consumed naturally in foods such as seafood and poultry. The taurine present in the energy drink is synthetically produced and has exactly the same characteristics and properties as the taurine produced by the body. Taurine plays an important role in several physiological functions, acting in osmotic regulation, immune function, glucose metabolism, as well as neurological and retinal development.
Segundo a ABIR, podemos destacar algumas informações importantes sobre as bebidas energéticas: According to ABIR, we can highlight some important information about energy drinks:
Bebidas energéticas são seguras e comercializadas em mais de 160 países. Os ingredientes responsáveis por seus benefícios, como cafeína, taurina e vitaminas, são substâncias cuja segurança é atestada por diversos órgãos e instituições nacionais e internacionais. Energy drinks are safe and marketed in over 160 countries. The ingredients responsible for its benefits, such as caffeine, taurine and vitamins, are substances whose safety is attested by various national and international bodies and institutions.
Os energéticos proporcionam maior disposição física, graças aos efeitos da cafeína presente na bebida. As vitaminas do complexo B presentes na maioria dos energéticos também contribuem para a redução do cansaço e da fadiga. Energizers provide greater physical disposition, thanks to the effects of the caffeine present in the drink. The B-complex vitamins present in most energy drinks also contribute to the reduction of tiredness and fatigue.
A crença de que os ingredientes produzidos sinteticamente, que também estão incluídos na maioria das bebidas energéticas, são perigosos e não são saudáveis é falsa. Os ingredientes fabricados sinteticamente garantem uma qualidade elevada, pois são produzidos em conformidade com os requisitos técnicos e regulatórios de cada local e desempenham a mesma função que os seus homólogos naturais. The belief that synthetically produced ingredients, which are also included in most energy drinks, are dangerous and not are healthy is false. Synthetically manufactured ingredients guarantee high quality, as they are produced in accordance with the technical and regulatory requirements of each location and perform the same function as their natural counterparts.
Não há base científica que indique que as bebidas energéticas provoquem qualquer interação com o álcool. Os consumidores devem estar conscientes de que o consumo excessivo de álcool pode ter efeitos adversos à saúde. There is no scientific basis to indicate that energy drinks cause any interaction with alcohol. Consumers should be aware that excessive alcohol consumption can have adverse health effects.
A taurina presente no energético é produzida sinteticamente e tem exatamente as mesmas características e propriedades da taurina produzida pelo corpo. A maioria das bebidas energéticas contêm a mesma quantidade ou até menos cafeína que uma xícara de café. The taurine present in the energy drink is synthetically produced and has exactly the same characteristics and properties as the taurine produced by the body. Most energy drinks contain the same amount or even less caffeine than a cup of coffee.
Como a nicotina é uma substância que integra a formulação da bebida energética proposta pelo presente pedido de Patente de Invenção, será feita a seguir uma descrição relativa à mesma. As nicotine is a substance that integrates the formulation of the energy drink proposed by the present patent application, a description of the same will be made below.
A nicotina é uma substância química que contém nitrogénio, que é feito por vários tipos de plantas, incluindo a planta do tabaco. Também é produzido sinteticamente. Nicotiana tabacum, o tipo de nicotina encontrado nas plantas de tabaco, vem da família do nightshade. Pimentão, berinjela, tomate e batata são exemplos da família dos nightshade. Nicotine is a nitrogen-containing chemical that is made by many types of plants, including the tobacco plant. It is also produced synthetically. Nicotiana tabacum, the type of nicotine found in tobacco plants, comes from the nightshade family. Peppers, eggplants, tomatoes and potatoes are examples of the nightshade family.
A Agência Internacional de Pesquisa em Câncer estabeleceu que a nicotina não é um agente carcinógeno, apontando que os reconhecidos males do consumo do cigarro são causados pelas demais substâncias tóxicas presentes no produto como o monóxido de carbono, alcatrão e muitas outras substancias consideradas nocivas. The International Agency for Research on Cancer established that nicotine is not a carcinogen, pointing out that the recognized evils of cigarette consumption are caused by other toxic substances present in the product, such as carbon monoxide, tar and many other substances considered harmful.
A planta do tabaco é originária das Américas e tem sido usada como medicamento e estimulante por pelo menos 2.000 anos. O seu nome deve- se ao diplomata francês Jean Nicot, que foi o difusor do tabaco na França. Embaixador francês em Lisboa, Jean Nicot trouxe esta planta de Portugal e deu-a a conhecer no seu país. The tobacco plant originates from the Americas and has been used as a medicine and stimulant for at least 2,000 years. Its name comes from the French diplomat Jean Nicot, who was the tobacco diffuser in France. French ambassador in Lisbon, Jean Nicot brought this plant from Portugal and made it known in his country.
É importante ressaltar que o tabaco é diferente de nicotina. O vício em tabaco é causado pelo aumento de dopamina nos circuitos de recompensa do cérebro tal como em outras drogas viciantes. Atualmente, aceita-se a hipótese de que outros compostos no fumo do tabaco que não a nicotina sejam inibidores da monoamina oxidase (MAO), a enzima responsável pela degradação da dopam ina no cérebro, ativa no circuito de recompensa. Importantly, tobacco is different from nicotine. Tobacco addiction is caused by an increase in dopamine in the brain's reward circuits as with other addictive drugs. Currently, the hypothesis of that compounds in tobacco smoke other than nicotine are inhibitors of monoamine oxidase (MAO), the enzyme responsible for breaking down dopamine in the brain, active in the reward circuit.
Muitas pessoas que desejam parar de fumar recorrem a pastilhas, gomas de mascar e adesivos de nicotina em doses equivalentes as consumidas pelos fumantes (este procedimento é chamado de TRN - Terapia de Reposição de Nicotina). As pastilhas, gomas de mascar e adesivos são vendidos em farmácias físicas e pela internet sem a necessidade de receituário médico. Many people who want to quit smoking use nicotine gum, gum and patches in doses equivalent to those consumed by smokers (this procedure is called NRT - Nicotine Replacement Therapy). The tablets, chewing gum and adhesives are sold in physical pharmacies and over the internet without the need for a prescription.
Segue abaixo exemplos de dosagens de nicotina praticadas no mercado: Below are examples of nicotine dosages practiced in the market:
Cigarro: Um cigarro contém até 2mg de nicotina. Um cigarro light possui de 0,6mg até 1 mg. Um cigarro regular possui de 1 ,2 mg - 1 ,4 mg. Uma pessoa que fuma um maço de cigarro por dia pode chegar consumir 24mg de nicotina. Cigarette: A cigarette contains up to 2mg of nicotine. A light cigarette has from 0.6mg to 1mg. A regular cigarette has 1.2 mg - 1.4 mg. A person who smokes a pack of cigarettes a day can consume 24mg of nicotine.
Goma de mascar: A goma de mascar de nicotina possui cerca 2 mg a 4mg de nicotina. Chewing Gum: Nicotine chewing gum has about 2mg to 4mg of nicotine.
Adesivo de nicotina: Um adesivo de nicotina possui de 15 mg a 30 mg de nicotina. Nicotine Patch: A nicotine patch contains 15mg to 30mg of nicotine.
Cigarro eletrónico: Um cigarro eletrónico pode possuir até 41 mg de nicotina Electronic Cigarette: An electronic cigarette can contain up to 41 mg of nicotine
Para efeito de entendimento da matéria aqui tratada, cumpre citar no presente texto material da ANVISA relativo ao tema. For the purpose of understanding the matter dealt with here, it is necessary to cite in this text material from ANVISA on the subject.
De acordo com a Lei n. 9.782/99, os produtos derivados do tabaco foram incluídos como bens de interesse da saúde e, dessa forma, devem ser regulamentados, controlados e fiscalizados. Assim, coube à Anvisa regular e registrar esses produtos. According to Law n. 9,782/99, tobacco products were included as goods of health interest and, therefore, must be regulated, controlled and inspected. Thus, it fell to Anvisa to regulate and register these products.
É valido ressaltar que produtos RDC n. 46, de 28 de agosto de 2009, art. 1o a ANVISA registra seu entendimento do que é produto derivado do tabaco e os classifica em três tipos: Produtos de tabaco queimados/combustíveis; Produtos de tabaco não geradores de fumaça (smokeless); Produtos de tabaco aquecidos/vaporizados. It is worth noting that RDC products n. 46, of August 28, 2009, art. 1 o ANVISA records its understanding of what a tobacco product is and classifies them into three types: Burnt tobacco products/fuels; Smokeless tobacco products; Heated/Steamed Tobacco Products.
Produtos de tabaco queimados/combustíveis Burnt Tobacco Products/Fuels
Cigarro: O cigarro é o produto mais conhecido no Brasil e pode ser composto de quatro maneiras: tabaco envolto por papel; tabaco homogeneizado ou reconstituído; uma mistura de celulose e tabaco; outro envoltório que não seja exclusivamente folha de tabaco. Cigarette: Cigarettes are the best known product in Brazil and can be composed in four ways: tobacco wrapped in paper; homogenized tobacco or reconstituted; a mixture of cellulose and tobacco; other wrap that is not exclusively tobacco leaf.
Charuto: O charuto é composto de folhas de tabaco inteiras, picadas, desfiadas ou partidas, enroladas formando um cilindro, com envoltório constituído por folha de tabaco ou tabaco reconstituído. Cigar: The cigar is composed of whole tobacco leaves, chopped, shredded or broken, rolled into a cylinder, with a wrapper consisting of tobacco leaf or reconstituted tobacco.
Cigarrilha: A cigarrilha caracteriza-se por ter peso menor que 1 .360 g/1.000 cigarrilhas. Ela é composta de folhas de tabaco, picadas, desfiadas, em pó ou partidas, formando um cilindro, e seu envoltório é constituído por folha de tabaco ou tabaco reconstituído. Cigarillo: The cigarillo is characterized by weighing less than 1,360 g/1,000 cigarillos. It is composed of tobacco leaves, chopped, shredded, powdered or broken, forming a cylinder, and its wrapping is constituted by tobacco leaf or reconstituted tobacco.
Fumo desfiado: O fumo desfiado é composto de folhas de tabaco desfiadas e pode ou não ser processado pela indústria, permitindo que o próprio usuário enrole o seu cigarro. Shredded tobacco: Shredded tobacco is composed of shredded tobacco leaves and may or may not be processed by the industry, allowing the user to roll their cigarette.
Fumo de rolo: Fumo de rolo, também chamado de fumo de corda, é feito de folhas de tabaco destaladas, entrelaçadas e enroladas, submetidas ao processo de cura ao sol. Coil smoke: Coil tobacco, also called rope tobacco, is made from peeled, intertwined, and rolled tobacco leaves that have undergone a sun-curing process.
Cachimbo: O cachimbo requer um fumo destinado ao seu uso, chamado fumo para cachimbo Pipe: The pipe requires a smoke intended for its use, called pipe tobacco
Cigarro kretek: O cigarro kretek, popularmente conhecido como cigarro de cravo ou cigarro de bali, é uma mistura de 60% a 80% de tabaco e 40% a 20% de cravo. Pode ser enrolado por papel, tabaco homogeneizado ou reconstituído, por uma mistura de celulose e tabaco, ou outro envoltório. Kretek cigarette: The kretek cigarette, popularly known as clove cigarette or bali cigarette, is a mixture of 60% to 80% tobacco and 40% to 20% clove. It can be wrapped in paper, homogenized or reconstituted tobacco, a mixture of cellulose and tobacco, or other wrapping.
Cigarro de palha: Cigarro de palha também é um dos produtos sem filtro. Sua composição é simples: tabaco picado enrolado em palha de milho. Straw cigarette: Straw cigarette is also one of the unfiltered products. Its composition is simple: chopped tobacco wrapped in corn husks.
Bidi: O bidi não tem filtro e é feito por uma pequena porção de tabaco picado envolto por folhas de tendu ou temburi, plantas nativas da Ásia. Bidi: Bidi has no filter and is made from a small portion of shredded tobacco wrapped in leaves of tendu or temburi, plants native to Asia.
Blunt: O blunt é considerado derivado do tabaco porque ele está presente em sua composição. Diferente dos demais produtos apresentados, é um envoltório utilizado para colocar fumo em seu interior (por exemplo, fumo desfiado) com a finalidade de serem fumados. Blunt: Blunt is considered a derivative of tobacco because it is present in its composition. Unlike the other products presented, it is a wrapper used to place tobacco inside (for example, shredded tobacco) with the purpose of being smoked.
Produtos de tabaco não geradores de fumaça (smokeless) Smokeless tobacco products
Tabaco inalável: Tabaco inalável, também conhecido como rapé, é um dos produtos compostos de tabaco que não gera fumaça, em razão de ser aspirado Snus: Com um nome diferente, o Snus, muito comum na Suécia, é constituído por tabaco úmido, em pó, para uso oral. Inhalable tobacco: Inhalable tobacco, also known as snuff, is one of the tobacco products that does not generate smoke due to being inhaled. Snus: With a different name, Snus, very common in Sweden, is made up of moist, powdered tobacco for oral use.
Fumo para mascar: Fumo para mascar, ou tabaco mascável, é um dos produtos de tabaco que não geram fumaça, utilizado para ser mascado ou sugado. Chewing tobacco: Chewing tobacco, or chewable tobacco, is one of the smokeless tobacco products used to be chewed or sucked.
Produtos de tabaco aquecidos/vaporizados Heated/Steamed Tobacco Products
Fumo para narguilé: Narguilé, cachimbo d'água, shisha ou hookah: o mesmo dispositivo tem vários nomes, e todos se referem ao equipamento que é utilizado com o fumo para narguilé - outro produto derivado do tabaco. O cachimbo de narguilé contém um recipiente denominado fornilho, que armazena o tabaco. Este pode ficar em contato com o carvão aceso e, portanto, ocorrer queima de matéria orgânica. Assim, a classificação de fumo para narguilé como produto de tabaco aquecido/vaporizado pode não abranger todas as possibilidades de emissões durante o seu uso. For hookah smoking: Hubble, pipe of water, or hookah shisha: the same device has several names, and all refer to equipment which is used for hookah smoking with - other tobacco product. The hookah pipe contains a container called a bowl, which stores the tobacco. This can come into contact with the burning charcoal and, therefore, burn organic matter. Thus, the classification of hookah smoke as a heated/vaporized tobacco product may not cover all possible emissions during its use.
Dispositivos eletrónicos: Dispositivos eletrónicos para fumar também são conhecidos como narguilé eletrónico, cigarros eletrónicos, e- cigarettes, e-ciggy, ecigar, entre outros, que podem ter diferentes formas, mas com o objetivo comum de simular o uso de produtos de tabaco como cigarros, cigarrilhas, charutos, cachimbos e similares. Esses equipamentos eletrónicos vaporizam um cartucho ou recipiente que contém extrato de folhas de tabaco. Podem utilizar também o líquido adquirido individualmente e conter nicotina ou não. Electronic devices: Electronic smoking devices are also known as electronic hookahs, electronic cigarettes, e-cigarettes, e-ciggy, ecigar, among others, which can have different forms, but with the common objective of simulating the use of tobacco products such as cigarettes, cigarillos, cigars, pipes and the like. These electronic devices vaporize a cartridge or container that contains tobacco leaf extract. They can also use the liquid purchased individually and contain nicotine or not.
Podemos identificar que a nicotina não faz parte da lista de produtos derivados do tabaco apontado pela ANVISA. We can identify that nicotine is not part of the list of tobacco products indicated by ANVISA.
Restrições de comunicação communication restrictions
A Legislação em vigor: Lei n° 12.546, de 14 de dezembro de 2011 , que alterou o art. 3o da Lei n° 9.294/1996, proibiu a propaganda de produtos derivados do tabaco, exceto a exposição destes à venda nos estabelecimentos comerciais. Current legislation: Law No. 12,546, of December 14, 2011, which amended art. 3 of Law No. 9.294 / 1996, prohibited the advertising of tobacco products, except for the exposure of these for sale in shops.
A Lei n° 10.167, de 27 de dezembro de 2000, deu nova redação à Lei n° 9.294/1996, incluindo a proibição da propaganda comercial dos produtos derivados do tabaco em jornais, revistas, televisão, internet, patrocínio de atividade cultural ou esportiva, e permitiu somente a propaganda por meio de pósteres, painéis e cartazes na parte interna do local de venda do produto. A RDC n° 15, de 17 de janeiro de 2003, estabeleceu as definições sobre propaganda comercial dos produtos derivados do tabaco, parte interna de locais de venda e proibiu a comercialização e a oferta dos produtos pela internet. Law No. 10.167, of December 27, 2000, amended Law No. 9,294/1996, including the prohibition of commercial advertising of tobacco products in newspapers, magazines, television, internet, sponsorship of cultural or sports activities , and only allowed advertising through posters, panels and posters inside the place where the product was sold. RDC No. 15, of January 17, 2003, established the definitions for commercial advertising of tobacco products, internal parts of sales outlets and prohibited the sale and offer of products on the internet.
A RDC n° 335/2003 também regulamentou a impressão das imagens e frases de advertência sanitária nos materiais de propaganda de produtos fumígenos derivados do tabaco. RDC No. 335/2003 also regulated the printing of health warning images and phrases in advertising materials for tobacco-derived smoking products.
A nicotina por não ser considerado um “produto de tabaco” não possui restrição de comunicação conforme analisado à luz da Lei. As nicotine is not considered a “tobacco product”, it has no communication restriction as analyzed in light of the Law.
PROBLEMAS DO ESTADO DA TÉCNICA PROBLEMS OF THE STATE OF THE TECHNIQUE
Um dos problemas que está relacionado ao estado da técnica diz respeito ao fato de que o cotidiano das cidades, as longas jornadas de trabalho e de estudos geraram uma sociedade extremamente competitiva. Esta competitividade faz com que as pessoas busquem formas de estarem vigilantes a todo momento para poder trabalhar mais, estudar mais e realizar todos os afazeres do dia a dia. Neste cenário as bebidas energéticas são consumidas como formas saudáveis de deixarem as pessoas acordadas. One of the problems related to the state of the art concerns the fact that the daily life of cities, the long work and study hours, have generated an extremely competitive society. This competitiveness makes people look for ways to be vigilant at all times so that they can work more, study more and carry out all the daily tasks. In this scenario, energy drinks are consumed as healthy ways to keep people awake.
Infelizmente a busca por constante vigília também gerou em nossa sociedade abusos de medicações estimulantes controladas, tal como o metilfenidato (mais conhecido pelo nome comercial de Ritalina). Pesquisa da Universidade Estadual do Rio de Janeiro (UERJ) mostra um aumento de quase 800% no consumo de metilfenidato de 2003 a 2012. O levantamento foi feito pela psicóloga Denise Barros, que estudou o consumo do remédio no país em sua tese de doutorado. Dados expostos na recomendação do Ministério da Saúde indicam que o Brasil se tornou o segundo mercado mundial no consumo do metilfenidato, com cerca de 2.000.000 de caixas vendidas no ano de 2010. Este abuso de medicações criadas para tratar transtornos como o Déficit de Atenção e Hiperatividade (TDAH) mostra abertamente que a população busca por formas de ficar desperta. Unfortunately, the search for constant wakefulness has also led to abuses of controlled stimulant medications in our society, such as methylphenidate (better known by the trade name of Ritalin). Research by the State University of Rio de Janeiro (UERJ) shows an increase of almost 800% in the consumption of methylphenidate from 2003 to 2012. The survey was carried out by psychologist Denise Barros, who studied the use of the drug in the country in her doctoral thesis. Data exposed in the recommendation of the Ministry of Health indicate that Brazil has become the second world market in the consumption of methylphenidate, with about 2,000,000 boxes sold in 2010. This abuse of medications created to treat disorders such as Attention Deficit and Hyperactivity (ADHD) openly shows that the population is looking for ways to stay awake.
Acreditamos que é nossa função social consiste em pesquisar, encontrar e levar a mercado produtos saudáveis que ajudem as pessoas a ficarem acordadas sem que necessitem recorrer e medicamentos. Neste cenário, na busca por uma alternativa saudável, foi criada uma formulação energética que usa nicotina em dose controlada com o propósito de ser um produto saudável e estimulante para nossa sociedade. We believe that our social function is to research, find and bring to market healthy products that help people stay awake without the need for medication. In this scenario, in the search for a healthy alternative, an energy formulation was created that uses nicotine in a controlled dose with the purpose of being a healthy and stimulating product for our society.
Outro problema relativo ao estado da técnica, neste caso específico à questão que envolve o uso da nicotina é que a nicotina, por estar presente no tabaco, acaba por ser marginalizada. Confunde-se os malefícios do monóxido de carbono, alcatrão e de outras substancias consideradas nocivas presentes no cigarro com a nicotina. Another problem related to the state of the art, in this case specific to the issue involving the use of nicotine, is that nicotine, being present in tobacco, ends up being marginalized. The harmful effects of carbon monoxide, tar and other substances considered harmful present in cigarettes are confused with nicotine.
A nicotina induz a liberação do neurotransmissor glutamato, um neurotransmissor excitatório envolvido na plasticidade sináptica, sendo esta uma das possíveis causas para o efeito da nicotina ser considerada uma substancia que auxilia a memória (embora não pela forma de tabaco, este um redutor da oxigenação cerebral). Nicotine induces the release of the neurotransmitter glutamate, an excitatory neurotransmitter involved in synaptic plasticity, which is one of the possible causes for the effect of nicotine to be considered a substance that aids memory (although not in the form of tobacco, this is a reducer of cerebral oxygenation ).
Segundo o neurologista Ricardo Teixeira, doutor em neurologia pela Unicamp e diretor clínico do Instituto do Cérebro de Brasília em matéria do Jornal Correio Brasiliense postado em 17/03/2014 11 :46 / atualizado em 17/03/2014, informa que já existem evidências de que adesivos de nicotina podem promover a melhora do desempenho cognitivo de idosos com problemas de memória, mas sem demência. Além da memória, a nicotina incrementa a atenção e a velocidade psicomotora. Entre jovens, já foi demonstrado que a nicotina pode incrementar de forma muito discreta a memória e a atenção. Segundo o Dr. Ricardo a nicotina estimula receptores nicotínicos do neurotransmissor acetilcolina no cérebro. Esses mesmos receptores são cada vez mais deficientes à medida que a Doença de Alzheimer progride. O doutor em neurologia ainda afirma que a nicotina modula outros sistemas de neurotransmissores. Isto é, se estivermos sonolentos, a nicotina acorda e, se estivermos ansiosos, a nicotina relaxa. O Dr. Ricardo ainda informa que a suspensão do uso de adesivos de nicotina não provoca abstinência e não existe tendência ao abuso. According to neurologist Ricardo Teixeira, Ph.D. in neurology from Unicamp and clinical director of the Instituto do Cérebro de Brasília in an article in the Jornal Correio Brasiliense posted on 03/17/2014 11:46 / updated on 03/17/2014, informs that there is already evidence that nicotine patches can improve cognitive performance in elderly people with memory problems but without dementia. In addition to memory, nicotine increases attention and psychomotor speed. Among young people, it has been shown that nicotine can very discreetly increase memory and attention. According to Dr. Ricardo, nicotine stimulates nicotinic receptors of the neurotransmitter acetylcholine in the brain. These same receptors are increasingly deficient as Alzheimer's disease progresses. The doctor of neurology also claims that nicotine modulates other neurotransmitter systems. That is, if we are sleepy, nicotine wakes up, and if we are anxious, nicotine relaxes. Dr. Ricardo also informs that the suspension of the use of nicotine patches does not cause withdrawal and there is no tendency to abuse.
Segundo estudos do Texas A & M College of Medicine, mesmo em doses elevadas, a nicotina não provocou efeitos colaterais comportamentais como ansiedade. According to studies by the Texas A & M College of Medicine, even at high doses, nicotine did not cause behavioral side effects such as anxiety.
Se a bebida ora proposta ajudar as pessoas a ficarem despertas reduzindo a busca por remédios controlados a função social do produto será atingida por completo. OBJETIVOS DA INVENÇÃO If the drink now proposed helps people to stay awake by reducing the search for controlled remedies, the social function of the product will be fully achieved. OBJECTIVES OF THE INVENTION
Em face do estado da técnica acima narrado, configura como sendo um dos objetivos deste pedido de Patente de Invenção propor a formulação de uma bebida estimulante que contém nicotina em doses controladas com objetivo de ajudar as pessoas a ficarem despertas com qualidade e de forma saudável. In view of the state of the art narrated above, it is one of the objectives of this patent application to propose the formulation of a stimulant drink that contains nicotine in controlled doses in order to help people stay awake with quality and in a healthy way.
É ainda um objetivo deste pedido de Patente de Invenção propor uma bebida estimulante que contém nicotina a qual possa ser produzida em larga escala, permitindo assim um custo acessível ao público consumidor. It is still an objective of this patent application to propose a stimulant drink that contains nicotine which can be produced on a large scale, thus allowing an accessible cost to the consuming public.
DESCRIÇÃO DA FIGURA: DESCRIPTION OF THE FIGURE:
Este pedido de Patente de Invenção será descrito de forma detalhada, mas para tal descrição se faz necessário o conteúdo retratado na figura 1 que representa um gráfico demonstrativo da quantidade de cafeína presente em diversos tipos de bebida, tendo por fonte a EFSA - Autoridade Europeia de Segurança Alimentar. This patent application will be described in detail, but for such description it is necessary the content depicted in figure 1 which represents a graphic showing the amount of caffeine present in various types of beverage, having as source the EFSA - European Authority of Food Safety.
DESCRIÇÃO DETALHADA DA INVENÇÃO DETAILED DESCRIPTION OF THE INVENTION
O presente pedido de Patente de Invenção propõe uma bebida estimulante que contém nicotina com objetivo de ajudar as pessoas a ficarem despertas com qualidade e de forma saudável. The present patent application proposes a stimulant drink that contains nicotine with the objective of helping people to stay awake with quality and in a healthy way.
A bebida pode ser classificada como energética. Por legislação, uma bebida pode ser considerada energética se tiver como ingredientes centrais uma ou mais dessas substâncias: inositol, glucoronolactona, taurina e cafeína. The drink can be classified as energetic. By legislation, a drink can be considered energetic if its central ingredients are one or more of these substances: inositol, glucuronolactone, taurine and caffeine.
A bebida em questão é formada prioritariamente por água, nicotina, açúcar, taurina, glucoronalactona, cafeína e inositol que são formulados em água e gás carbónico. Adicionalmente na formação estão presentes ingredientes de suporte comumente encontrados em bebidas gaseificadas, tais como acidulante, antioxidante, regulador de acidez, citrato de sódio, aromatizante, corante, conservante, sorbato de potássio, edulcorantes e neotame. The drink in question is primarily formed by water, nicotine, sugar, taurine, glucuronalactone, caffeine and inositol which are formulated in water and carbon dioxide. Additionally, supporting ingredients commonly found in carbonated beverages are present in the formation, such as acidulant, antioxidant, acidity regulator, sodium citrate, flavoring, colorant, preservative, potassium sorbate, sweeteners and neotame.
A formulação em questão pode possuir diferentes configurações centrais, com destaque para:
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The formulation in question may have different central configurations, with emphasis on:
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O processo produtivo das formulações não configura o objeto a ser protegido pelo presente pedido de patente de invenção, mas para que o mesmo possa ser perfeitamente entendido, deve ser ressaltado que o mesmo é baseado em homogeneização por reator. Como exemplo segue o detalhamento do processo de produção da formulação Configuração 1 :
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The production process of the formulations does not configure the object to be protected by this patent application, but so that it can be perfectly understood, it should be emphasized that it is based in reactor homogenization. As an example, the detailing of the production process of the Configuration 1 formulation follows:
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Segue descrição do Processo produtivo utilizado para a obtenção da bebida estimulante objeto deste pedido de Patente de Invenção.
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Below is a description of the production process used to obtain the stimulant drink object of this patent application.
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Claims

REIVINDICAÇÕES
1. “BEBIDA ESTIMULANTE”, a qual é caracterizada por apresentar uma primeira formulação denominada como configuração 1 , que consiste em: Taurina (de 10mg até 400mg/100ml); Nicotina (de 0,1 mg até 40mg/100ml); Glucoronalactona (de 10mg até 300mg/100ml); Cafeína (de 3mg até 40mg/100ml); Inositol (de 1 mg até 20mg/100ml); Açúcares (de 7g a 33g/100ml); Água (269ml ou de acordo com a configuração do produto); e Gás carbónico. 1. "STIMULATING BEVERAGE", which is characterized by presenting a first formulation called configuration 1 , which consists of: Taurine (from 10mg to 400mg/100ml); Nicotine (from 0.1 mg to 40mg/100ml); Glucoronalactone (10mg to 300mg/100ml); Caffeine (3mg to 40mg/100ml); Inositol (1mg to 20mg/100ml); Sugars (7g to 33g/100ml); Water (269ml or according to product configuration); and Carbon dioxide.
2. “BEBIDA ESTIMULANTE”, de acordo com a reivindicação 1 , caracterizada pela formulação apresentar uma variante denominada como configuração 2, a qual consiste em: Nicotina (de 0,1 mg até 40mg/100ml); Glucoronalactona (de 10mg até 300mg/100ml); Cafeína (de 3mg até 40mg/100ml); Inositol (de 0,5mg até 20mg/100ml); Açúcares (de 7g a 33g/100ml); Água (269ml ou de acordo com a configuração do produto); e Gás carbónico. 2. "STIMULANT BEVERAGE", according to claim 1, characterized in that the formulation presents a variant called configuration 2, which consists of: Nicotine (from 0.1 mg to 40mg/100ml); Glucoronalactone (10mg to 300mg/100ml); Caffeine (3mg to 40mg/100ml); Inositol (from 0.5mg to 20mg/100ml); Sugars (7g to 33g/100ml); Water (269ml or according to product configuration); and Carbon dioxide.
3. “BEBIDA ESTIMULANTE”, de acordo com a reivindicação 1 , caracterizada pela formulação apresentar uma variante denominada como configuração 3, a qual consiste em: Taurina (de 10mg até 400mg/100ml); Nicotina (de 0,1 mg até 40mg/100ml); Cafeína (de 3mg até 40mg/100ml); Inositol (de 1 mg até 20mg/100ml); Açúcares (de 7g a 33g/100ml); Água (269ml ou de acordo com a configuração do produto); e Gás carbónico. 3. "STIMULATING BEVERAGE", according to claim 1, characterized in that the formulation has a variant called configuration 3, which consists of: Taurine (from 10mg to 400mg/100ml); Nicotine (from 0.1 mg to 40mg/100ml); Caffeine (3mg to 40mg/100ml); Inositol (1mg to 20mg/100ml); Sugars (7g to 33g/100ml); Water (269ml or according to product configuration); and Carbon dioxide.
4. “BEBIDA ESTIMULANTE”, de acordo com a reivindicação 1 , caracterizada pela formulação apresentar uma variante denominada como configuração 4, a qual consiste em: Taurina (de 10mg até 400mg/100ml); Nicotina (de 0,1 mg até 40mg/100ml); Glucoronalactona (de 10mg até 300mg/100ml); Inositol (de 1 mg até 20mg/100ml); Açúcares (de 7g a 33g/100ml); Água (269ml ou de acordo com a configuração do produto); e Gás carbónico. 4. "STIMULANT BEVERAGE", according to claim 1, characterized in that the formulation presents a variant called configuration 4, which consists of: Taurine (from 10mg to 400mg/100ml); Nicotine (from 0.1 mg to 40mg/100ml); Glucoronalactone (10mg to 300mg/100ml); Inositol (1mg to 20mg/100ml); Sugars (7g to 33g/100ml); Water (269ml or according to product configuration); and Carbon dioxide.
5. “BEBIDA ESTIMULANTE”, de acordo com a reivindicação 1 , caracterizada pela formulação apresentar uma variante denominada como configuração 5, a qual consiste em: Taurina (de 10mg até 400mg/100ml); Nicotina (de 0,1 mg até 40mg/100ml); Glucoronalactona (de 10mg até 300mg/100ml); Cafeína (de 3mg até 40mg/100ml); Açúcares (de 7g a 33g/100ml); Água (269ml ou de acordo com a configuração do produto); e Gás carbónico. 5. "STIMULANT BEVERAGE", according to claim 1, characterized in that the formulation has a variant called configuration 5, which consists of: Taurine (from 10mg to 400mg/100ml); Nicotine (from 0.1 mg to 40mg/100ml); Glucoronalactone (10mg to 300mg/100ml); Caffeine (3mg to 40mg/100ml); Sugars (7g to 33g/100ml); Water (269ml or according to product configuration); and Carbon dioxide.
6. “BEBIDA ESTIMULANTE”, de acordo com a reivindicação 1 , caracterizada pela formulação apresentar uma variante denominada como configuração 6, a qual consiste em: Nicotina (de 0,1 mg até 40mg/100ml); Cafeína (de 3mg até 40mg/100ml); Açúcares (de 7g a 33g/100ml); Água (269ml ou de acordo com a configuração do produto); e Gás carbónico. 6. "STIMULANT BEVERAGE", according to claim 1, characterized in that the formulation presents a variant called configuration 6, which consists of: Nicotine (from 0.1 mg to 40mg/100ml); Caffeine (3mg to 40mg/100ml); Sugars (7g to 33g/100ml); Water (269ml or according to product configuration); and Carbon dioxide.
7. “BEBIDA ESTIMULANTE”, de acordo com a reivindicação 1 , caracterizada pela formulação apresentar uma variante denominada como configuração 7, a qual consiste em: Taurina (de 10mg até 400mg/100ml); Nicotina (de 0,1 mg até 40mg/100ml); Açúcares (de 7g a 33g/100ml); Água (269ml ou de acordo com a configuração do produto); e Gás carbónico. 7. "STIMULATING BEVERAGE", according to claim 1, characterized in that the formulation has a variant called configuration 7, which consists of: Taurine (from 10mg to 400mg/100ml); Nicotine (from 0.1 mg to 40mg/100ml); Sugars (7g to 33g/100ml); Water (269ml or according to product configuration); and Carbon dioxide.
8. “BEBIDA ESTIMULANTE”, de acordo com a reivindicação 1 , caracterizada pela formulação apresentar uma variante denominada como configuração 8, a qual consiste em: Taurina (de 10mg até 400mg/100ml); Nicotina (de 0,1 mg até 40mg/100ml); Inositol (de 1 mg até 20mg/100ml); Açúcares (de 7g a 33g/100ml); Água (269ml ou de acordo com a configuração do produto); e Gás carbónico. 8. "STIMULANT BEVERAGE", according to claim 1, characterized in that the formulation has a variant called configuration 8, which consists of: Taurine (from 10mg to 400mg/100ml); Nicotine (from 0.1 mg to 40mg/100ml); Inositol (1mg to 20mg/100ml); Sugars (7g to 33g/100ml); Water (269ml or according to product configuration); and Carbon dioxide.
9. “BEBIDA ESTIMULANTE”, de acordo com a reivindicação 1 , caracterizada pela formulação apresentar uma variante denominada como configuração 9, a qual consiste em: Nicotina (de 0,1 mg até 40mg/100ml); Glucoronalactona (de 10mg até 300mg/100ml); Açúcares (de 7g a 33g/100ml); Água (269ml ou de acordo com a configuração do produto); e Gás carbónico. 9. "STIMULANT BEVERAGE", according to claim 1, characterized in that the formulation presents a variant called configuration 9, which consists of: Nicotine (from 0.1 mg to 40mg/100ml); Glucoronalactone (10mg to 300mg/100ml); Sugars (7g to 33g/100ml); Water (269ml or according to product configuration); and Carbon dioxide.
10. “BEBIDA ESTIMULANTE”, de acordo com a reivindicação 1 , caracterizada pela formulação apresentar uma variante denominada como configuração 10, a qual consiste em: Nicotina (de 0,1 mg até 40mg/100ml); Inositol10. "STIMULANT BEVERAGE", according to claim 1, characterized in that the formulation presents a variant called configuration 10, which consists of: Nicotine (from 0.1 mg to 40mg/100ml); Inositol
(de 1mg até 20mg/100ml); Açúcares (de 7g a 33g/100ml); Água (269ml ou de acordo com a configuração do produto); e Gás carbónico. (from 1mg to 20mg/100ml); Sugars (7g to 33g/100ml); Water (269ml or according to product configuration); and Carbon dioxide.
11. “BEBIDA ESTIMULANTE”, de acordo com a reivindicação 1 , caracterizada pela formulação apresentar uma variante denominada como configuração 11 , a qual consiste em: Taurina (de 10mg até 400mg/100ml); Nicotina (de 0,1 mg até 40mg/100ml); Glucoronalactona (de 10mg até 300mg/100ml); Cafeína (de 3mg até 40mg/100ml); Inositol (de 0,5mg até 20mg/100ml); Semente de guaraná (de 2mg até 40mg/1 OOrnl); Açúcares (de 7g a 33g/1 OOrnl); Água (269ml ou de acordo com a configuração do produto); e Gás carbónico. 11. "STIMULATING BEVERAGE", according to claim 1, characterized in that the formulation has a variant called configuration 11, which consists of: Taurine (from 10mg to 400mg/100ml); Nicotine (from 0.1 mg to 40mg/100ml); Glucoronalactone (10mg to 300mg/100ml); Caffeine (3mg to 40mg/100ml); Inositol (from 0.5mg to 20mg/100ml); Guarana seed (from 2mg to 40mg/1 OOrnl); Sugars (7g to 33g/1 ORnl); Water (269ml or according to product configuration); and Carbon dioxide.
12. “BEBIDA ESTIMULANTE”, de acordo com a reivindicação 1 , caracterizada pela formulação apresentar uma variante denominada como configuração 12, a qual consiste em: Taurina (de lOmg até 400mg/100ml); Nicotina (de 0,1 mg até 40mg/100ml); Glucoronalactona (de 10mg até 300mg/100ml); Cafeína (de 3mg até 40mg/1 OOrnl); Inositol (de 1 mg até 20mg/1 OOrnl); Xilitol (de 7g a 33g/1 OOrnl); Água (269ml ou de acordo com a configuração do produto); e Gás carbónico. 12. "STIMULATING BEVERAGE", according to claim 1, characterized in that the formulation has a variant called configuration 12, which consists of: Taurine (from 10mg to 400mg/100ml); Nicotine (from 0.1 mg to 40mg/100ml); Glucoronalactone (10mg to 300mg/100ml); Caffeine (from 3mg to 40mg/1 OOrnl); Inositol (from 1mg to 20mg/1 OOrnl); Xylitol (7g to 33g/1Ornl); Water (269ml or according to product configuration); and Carbon dioxide.
13. “BEBIDA ESTIMULANTE”, de acordo com a reivindicação 1 , caracterizada pela formulação apresentar uma variante denominada como configuração 13, a qual consiste em: Nicotina (de 0,1 mg até 40mg/1 OOrnl); Glucoronalactona (de 10mg até 300mg/1 OOrnl); Cafeína (de 3mg até 40mg/1 OOrnl); Inositol (de 0,5mg até 20mg/1 OOrnl); Xilitol (de 7g a 33g/1 OOrnl); Água (269ml ou de acordo com a configuração do produto); e Gás carbónico. 13. "STIMULANT BEVERAGE", according to claim 1, characterized in that the formulation presents a variant called configuration 13, which consists of: Nicotine (from 0.1 mg to 40mg/1 OOrnl); Glucoronalactone (from 10mg to 300mg/1 OOrnl); Caffeine (from 3mg to 40mg/1 OOrnl); Inositol (from 0.5mg to 20mg/1 OOrnl); Xylitol (7g to 33g/1Ornl); Water (269ml or according to product configuration); and Carbon dioxide.
14. “BEBIDA ESTIMULANTE”, de acordo com a reivindicação 1 , caracterizada pela formulação apresentar uma variante denominada como configuração 14, a qual consiste em: Taurina (de lOmg até 400mg/100ml); Nicotina (de 0,1 mg até 40mg/1 OOrnl); Cafeína (de 3mg até 40mg/1 OOrnl); Inositol (de 1 mg até 20mg/1 OOrnl); Xilitol (de 7g a 33g/1 OOrnl); Água (269ml ou de acordo com a configuração do produto); e Gás carbónico. 14. "STIMULATING BEVERAGE", according to claim 1, characterized in that the formulation presents a variant called configuration 14, which consists of: Taurine (from 10mg to 400mg/100ml); Nicotine (from 0.1mg to 40mg/1Ornl); Caffeine (from 3mg to 40mg/1 OOrnl); Inositol (from 1mg to 20mg/1 OOrnl); Xylitol (7g to 33g/1Ornl); Water (269ml or according to product configuration); and Carbon dioxide.
15. “BEBIDA ESTIMULANTE”, de acordo com a reivindicação 1 , caracterizada pela formulação apresentar uma variante denominada como configuração 15, a qual consiste em: Taurina (de lOmg até 400mg/100ml); Nicotina (de 0,1 mg até 40mg/1 OOrnl); Glucoronalactona (de 10mg até 300mg/1 OOrnl); Inositol (de 1 mg até 20mg/1 OOrnl); Xilitol (de 7g a 33g/1 OOrnl); Água (269ml ou de acordo com a configuração do produto); e Gás carbónico. 15. "STIMULATING BEVERAGE", according to claim 1, characterized in that the formulation has a variant called configuration 15, which consists of: Taurine (from 10mg to 400mg/100ml); Nicotine (from 0.1mg to 40mg/1Ornl); Glucoronalactone (from 10mg to 300mg/1 OOrnl); Inositol (from 1mg to 20mg/1 OOrnl); Xylitol (7g to 33g/1Ornl); Water (269ml or according to product configuration); and Carbon dioxide.
16. “BEBIDA ESTIMULANTE”, de acordo com a reivindicação 1 , caracterizada pela formulação apresentar uma variante denominada como configuração 16, a qual consiste em: Taurina (de lOmg até 400mg/100ml); Nicotina (de 0,1 mg até 40mg/1 OOrnl); Glucoronalactona (de 10mg até 300mg/1 OOrnl); Cafeína (de 3mg até 40mg/1 OOrnl); Xilitol (de 7g a 33g/1 OOrnl); Água (269ml ou de acordo com a configuração do produto); e Gás carbónico. 16. "STIMULATING BEVERAGE", according to claim 1, characterized in that the formulation presents a variant called configuration 16, which consists of: Taurine (from 10mg to 400mg/100ml); Nicotine (from 0.1mg to 40mg/1Ornl); Glucoronalactone (from 10mg to 300mg/1 OOrnl); Caffeine (from 3mg to 40mg/1 OOrnl); Xylitol (7g to 33g/1Ornl); Water (269ml or according to product configuration); and Carbon dioxide.
17. “BEBIDA ESTIMULANTE”, de acordo com a reivindicação 1 , caracterizada pela formulação apresentar uma variante denominada como configuração 17, a qual consiste em: Taurina (de 10mg até 400mg/100ml); Nicotina (de 0,1 mg até 40mg/100ml); Glucoronalactona (de 10mg até 300mg/100ml); Cafeína (de 3mg até 35mg/100ml); Inositol (de 0,5mg até 20mg/100ml); Semente de guaraná (de 2mg até 6mg/100ml); Xilitol (de 7g a 33g/100ml); Água (269ml ou de acordo com a configuração do produto); e Gás carbónico. 17. "STIMULATING BEVERAGE", according to claim 1, characterized in that the formulation presents a variant called configuration 17, which consists of: Taurine (from 10mg to 400mg/100ml); Nicotine (from 0.1 mg to 40mg/100ml); Glucoronalactone (10mg to 300mg/100ml); Caffeine (3mg to 35mg/100ml); Inositol (from 0.5mg to 20mg/100ml); Guarana seed (2mg to 6mg/100ml); Xylitol (7g to 33g/100ml); Water (269ml or according to product configuration); and Carbon dioxide.
18. “BEBIDA ESTIMULANTE”, de acordo com a reivindicação 1 , caracterizada pela formulação apresentar uma variante denominada como configuração 18, a qual consiste em: Nicotina (de 0,1 mg até 40mg/100ml); Cafeína (de 3mg até 40mg/100ml); Xilitol (de 7g a 33g/100ml); Água (269ml ou de acordo com a configuração do produto); e Gás carbónico. 18. "STIMULATING BEVERAGE", according to claim 1, characterized in that the formulation presents a variant called configuration 18, which consists of: Nicotine (from 0.1 mg to 40mg/100ml); Caffeine (3mg to 40mg/100ml); Xylitol (7g to 33g/100ml); Water (269ml or according to product configuration); and Carbon dioxide.
19. “BEBIDA ESTIMULANTE”, de acordo com a reivindicação 1 , caracterizada pela formulação apresentar uma variante denominada como configuração 19, a qual consiste em: Taurina (de lOmg até 400mg/100ml); Nicotina (de 0,1 mg até 40mg/100ml); Xilitol (de 7g a 33g/100ml); Água (269ml ou de acordo com a configuração do produto); e Gás carbónico. 19. "STIMULATING BEVERAGE", according to claim 1, characterized in that the formulation presents a variant called configuration 19, which consists of: Taurine (from 10mg to 400mg/100ml); Nicotine (from 0.1 mg to 40mg/100ml); Xylitol (7g to 33g/100ml); Water (269ml or according to product configuration); and Carbon dioxide.
20. “BEBIDA ESTIMULANTE”, de acordo com a reivindicação 1 , caracterizada pela formulação apresentar uma variante denominada como configuração 20, a qual consiste em: Taurina (de lOmg até 400mg/100ml); Nicotina (de 0,1 mg até 40mg/100ml); Inositol (de 1mg até 20mg/100ml); Xilitol (de 7g a 33g/100ml); Água (269ml ou de acordo com a configuração do produto); e Gás carbónico. 20. "STIMULATING BEVERAGE", according to claim 1, characterized in that the formulation presents a variant called configuration 20, which consists of: Taurine (from 10mg to 400mg/100ml); Nicotine (from 0.1 mg to 40mg/100ml); Inositol (from 1mg to 20mg/100ml); Xylitol (7g to 33g/100ml); Water (269ml or according to product configuration); and Carbon dioxide.
21. “BEBIDA ESTIMULANTE”, de acordo com a reivindicação 1 , caracterizada pela formulação apresentar uma variante denominada como configuração 21 , a qual consiste em: Nicotina (de 0,1 mg até 40mg/100ml); Glucoronalactona (de 10mg até 300mg/100ml); Xilitol (de 7g a 33g/100ml); Água (269ml ou de acordo com a configuração do produto); e Gás carbónico. 21. "STIMULATING BEVERAGE", according to claim 1, characterized in that the formulation presents a variant called configuration 21, which consists of: Nicotine (from 0.1 mg to 40mg/100ml); Glucoronalactone (10mg to 300mg/100ml); Xylitol (7g to 33g/100ml); Water (269ml or according to product configuration); and Carbon dioxide.
22. “BEBIDA ESTIMULANTE”, de acordo com a reivindicação 1 , caracterizada pela formulação apresentar uma variante denominada como configuração 22, a qual consiste em: Nicotina (de 0,1 mg até 40mg/100ml); Inositol22. "STIMULATING BEVERAGE", according to claim 1, characterized in that the formulation presents a variant called configuration 22, which consists of: Nicotine (from 0.1 mg to 40mg/100ml); Inositol
(de 1 mg até 20mg/100ml); Xilitol (de 7g a 33g/100ml); Água (269ml ou de acordo com a configuração do produto); Gás carbónico. (from 1 mg to 20mg/100ml); Xylitol (7g to 33g/100ml); Water (269ml or according to product configuration); Carbon dioxide.
PCT/BR2021/050041 2020-01-31 2021-01-27 Stimulating beverage WO2021151184A1 (en)

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