WO2021103914A1 - 在线灭菌管式离心机以及优化系统和使用步骤 - Google Patents
在线灭菌管式离心机以及优化系统和使用步骤 Download PDFInfo
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- WO2021103914A1 WO2021103914A1 PCT/CN2020/124785 CN2020124785W WO2021103914A1 WO 2021103914 A1 WO2021103914 A1 WO 2021103914A1 CN 2020124785 W CN2020124785 W CN 2020124785W WO 2021103914 A1 WO2021103914 A1 WO 2021103914A1
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- WIPO (PCT)
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- main shaft
- drum
- rotating drum
- tube centrifuge
- online sterilization
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Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B9/00—Drives specially designed for centrifuges; Arrangement or disposition of transmission gearing; Suspending or balancing rotary bowls
- B04B9/08—Arrangement or disposition of transmission gearing ; Couplings; Brakes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/26—Accessories or devices or components used for biocidal treatment
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B15/00—Other accessories for centrifuges
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16J—PISTONS; CYLINDERS; SEALINGS
- F16J15/00—Sealings
- F16J15/02—Sealings between relatively-stationary surfaces
- F16J15/06—Sealings between relatively-stationary surfaces with solid packing compressed between sealing surfaces
Definitions
- the invention relates to a centrifuge, in particular to a tubular centrifuge.
- centrifuge methods there are centrifuge drum methods, filter separation methods using filters, and electrical separation methods using electrical charges of pharmaceutical materials.
- the medical use of the separated and cleaned pharmaceutical materials is for the transplantation of hematopoietic dry pharmaceutical materials, adoptive pharmaceutical material immunotherapy, gene therapy and other treatments using pharmaceutical materials, the aseptic separation and cleaning of pharmaceutical materials gradually become a very important subject.
- the present invention provides a structure of a tubular centrifuge, the purpose of which is to achieve a completely sealed online cleaning/sterilization. Specifically, after the material is removed from the rotating drum, the rotating drum is reinstalled in the centrifuge to achieve the The cleaning and sterilization is performed in a completely sealed environment, and the sealed state is maintained until the centrifuge is used next time, so as to ensure that the inside of the centrifuge (especially the drum) does not touch the outside at all, forming a complete aseptic state.
- the present invention provides an online sterilization tube centrifuge that can automatically and semi-automatically perform high-temperature cleaning and sterilization in a completely sealed state.
- the first embodiment of the online sterilization tube centrifuge includes: a rotating drum that separates substances and liquids by rotating centrifugal force; a main shaft connected and fixed to the rotating drum through a rotating drum connector; and A bearing unit for supporting the rotation of the main shaft; a tubular centrifuge, characterized in that a sleeve with a groove formed on the upper surface is provided above the bearing unit; the main shaft penetrates the sleeve and is A through hole is formed on the upper end side; the through hole formed on the upper end side of the spindle is inserted with a plug that can be inserted into the groove on the upper surface of the sleeve.
- the pin on the main shaft is inserted into the groove on the upper surface of the sleeve, so that when the main shaft rotates, the groove and the drum are driven to rotate. So as to realize the separation of material and liquid in normal operation.
- the drum is lifted up a certain distance and rotated a certain distance (within 90°), so that the pin on the main shaft is misaligned with the groove on the upper surface of the shaft sleeve, thereby The plug pin is locked on the upper surface of the shaft sleeve, and at this time, the rotating drum connecting piece abuts against the bearing unit to form a sealed space.
- the second embodiment of the online sterilization tube centrifuge includes: a rotating drum that separates substances and liquids by rotating centrifugal force; a main shaft connected and fixed to the rotating drum through a rotating drum connector; and A bearing unit for supporting the rotation of the main shaft; a tubular centrifuge, characterized in that a drum tray mechanism is provided below the rotating drum; the rotating drum tray mechanism includes: an upper surface formed with the A rotating drum tray with a meshing shape on the lower surface of the rotating drum; and a bracket formed under the rotating drum tray; the rotating drum tray mechanism can be moved up and down by a moving device.
- the rotating drum tray when the centrifuge is separating the material and liquid, the rotating drum tray is moved downward by a certain distance by the moving device, so that when the main shaft rotates, the rotating drum is driven to rotate without rubbing against the rotating drum tray. , So as to achieve normal operation to achieve material-liquid separation.
- the rotating drum tray is moved upward for a certain distance by the moving device, so that the rotating drum connecting piece abuts against the bearing unit to form a sealed space.
- the moving device is a cylinder-connected hydraulic mechanism or a pneumatic mechanism, or the moving device is an eccentric wheel arranged on a bracket. .
- the rotating drum since the weight of the rotating drum is relatively large, the rotating drum can be moved upward by mechanical means or the principle of leverage.
- a sealing ring is provided above the rotating drum connection member.
- the sealing effect can be further improved.
- the present invention also provides an operation step of the online sterilization tube centrifuge in the first embodiment, which is characterized in that it comprises the following step: stagger the pin on the main shaft to the groove on the upper surface of the shaft sleeve, The pin is locked on the upper surface of the main shaft.
- the present invention also provides an operation step of the online sterilization tube centrifuge in the second embodiment, which is characterized in that it comprises the following step: the drum tray mechanism is used to lift the drum upward for a certain distance.
- Figure 1 is a perspective view of the online sterilization tube centrifuge of the present invention
- Figure 2 is a front view of the cross sleeve of the present invention.
- Figure 3 is a top view of the operating state of the cross sleeve of the present invention.
- Figure 4 is a top view of the sealing operating state of the cross sleeve of the present invention.
- Fig. 5 is an enlarged schematic diagram of part A in Fig. 1 in the operating state of the online sterilization tube centrifuge of the present invention
- Fig. 6 is an enlarged schematic diagram of part A in Fig. 1 in the sealed state of the online sterilization tube centrifuge of the present invention
- Figure 7 is a perspective view of the online sterilization tube centrifuge of the present invention when the drum tray mechanism is installed;
- Fig. 8 is an enlarged schematic diagram of part B in Fig. 1 of the online sterilization tube centrifuge of the present invention.
- the on-line sterilization tube centrifuge of the present invention includes: a rotating drum 1, a main shaft 3 fixedly connected to the upper end of the rotating drum 1 through a rotating drum connector 4, and a bearing unit 2 for supporting the rotation of the main shaft 3 , And a lower damping under the rotating drum 1 for supporting the rotating drum 1, a feeding pipe penetrating the lower damping and extending to a certain distance from the opening of the lower end of the rotating drum 1, etc.
- the sealed state cannot be achieved, so that the rotating drum 1 cannot be sterilized, or the sealed storage sterilized state cannot be achieved after sterilization.
- the present invention provides the following two static sealing methods, so that the drum 1 can be directly cleaned and sterilized by external operations in the state of being installed in the casing, and after the sterilization is completed, the sterilization state can be maintained until the next time. Material separation operation.
- the main improved part is the part shown in area A in FIG. 1.
- the cross sleeve 5 is formed into a substantially cylindrical shape, and an opening through which the spindle 3 penetrates is formed at the center position.
- a cross-shaped groove is formed on the upper surface of the cross shaft sleeve 5.
- a pin through hole 31 is formed at the upper end of the main shaft 3, and a character pin 32 is penetrated through the opening.
- a slotted pin 32 penetrating through the upper end of the main shaft 3 can engage with a groove on the upper surface of the cross sleeve 4.
- the main shaft 3 is connected and fixed to the rotating drum 1 through the rotating drum connecting piece 4.
- the inline pin 32 on the main shaft 3 is inserted into the groove on the cross shaft sleeve 5 to form a state as shown in FIG. 3.
- the drum connecting sleeve 4 and the bearing unit 2, as shown in Fig. 5 are not in contact with each other to affect the rotation of the drum 1. Therefore, when the main shaft 1 receives the power of the motor and rotates, the cross sleeve 5 is driven to rotate together by the engagement of the flat pin 32, and the lower end of the rotary drum 1 is driven to rotate together through the drum connector 4 to separate the material and the liquid.
- the main shaft 3 is lifted for a certain distance, and the main shaft 3 is manually/electrically rotated for a certain distance, so that the slotted pin 32 on the main shaft 3 is staggered with the groove on the cross sleeve 5 At this time, when the main shaft 3 is released, the inline pin 32 is not inserted into the groove of the cross shaft sleeve, and thus is locked on the upper surface of the cross shaft sleeve 5.
- the sealing structure of the lower machine head in this embodiment adopts the cross shaft sleeve 5, and the cross-shaped grooves are formed on the upper surface of the cross-shaped groove.
- the present invention is not limited to this. Only a groove is formed on the upper surface of 5".
- the sealing structure of the lower machine head in this embodiment adopts the cross shaft sleeve 5, and the cross-shaped grooves are formed on the upper surface of the cross-shaped groove.
- the present invention is not limited to this. Only a groove is formed on the upper surface of 5".
- a first sealing ring 6 may be provided on the lower surface of the bearing unit 2 where it contacts the drum connecting sleeve 4, thereby further improving the sealing effect.
- a second sealing ring 7 and a third sealing ring 8 may be further provided, so as to further improve the sealing effect.
- the main improved part is the part shown in area B in FIG. 1.
- the drum tray mechanism 7 below the drum 1 the static sealing state of the tube centrifuge is realized.
- the drum tray mechanism 7 includes: a drum tray 71 and three brackets 72 formed below the drum tray 71.
- the rotating drum tray 71 is formed into a substantially disc shape with a center depression penetrating through, and the depression surface can be kneaded with the bottom of the rotating drum 1.
- an opening is formed in the drum tray 71 near the door opening direction of the casing, so as to facilitate the insertion of the drum 1.
- the bracket 72 is formed in the shape of a stick (rod), which is used to support the rotating drum tray 71, which penetrates through the plate at the lower end of the casing, and is provided with eccentric wheels on the left and right brackets 72 to realize the lifting of the bracket 72.
- the drum tray 71 is raised and lowered in the vertical direction through the eccentric on the bracket 72.
- a hydraulic or pneumatic mechanism connected with cylinders, and by applying or releasing pressure into the hydraulic or pneumatic mechanism, the up-and-down direction of the drum tray 71 can be raised and lowered.
- a sealing ring 6 can be provided on the lower surface of the bearing unit 2 where it contacts the drum connection sleeve 4 to further improve the sealing effect.
Abstract
一种在线灭菌管式离心机，其包括：通过旋转离心力进行物液分离的转鼓（1）；通过转鼓连接件（4）与所述转鼓（1）连接固定的主轴（3）；以及具有用于支承所述主轴（3）旋转的轴承单元（2），轴承单元（2）的上方还设置有上表面形成有凹槽的轴套（5）；所述主轴（3）贯穿该轴套（5），并在上端侧形成有贯通孔（31）；所述主轴（3）上端侧形成的贯通孔（31）插入有可嵌入所述轴套（5）上表面的凹槽内的插销（32），该在线灭菌管式离心机可以使离心机形成静密封状态，从而对转鼓进行清洗灭菌，实现了离心机的自动一体化。
Description
本发明涉及离心机、具体而言涉及一种管式离心机。
以往，作为分离和清洗制药物料等的方法，有利用离心机的方法、使用离心机转鼓的方法、使用过滤器的过滤分离法、以及利用制药物料的电荷的电分离法、利用存在于制药物料表面的抗原的亲和性的亲和分离法等。
一方面，由于作为经过分离和清洗的制药物料的医疗用途为用于造血干制药物料移植、过继制药物料免疫疗法、基因治疗等使用制药物料的治疗，因此，无菌分离和清洗制药物料就逐渐成为很重要的课题。
另一方面，近年来关于假疫苗等事件的发生，追其根源正是由于疫苗制作过程中需要完成无菌操作，而使用传统离心机无法避免与外界接触，这就需要制作疫苗、生物细胞、免疫物料等物料时离心机整个处于无菌密室，而这种制作方法其成本自然非常高昂。因此如何低成本形成完成的密封空间对离心机进行清洗灭菌，并在灭菌之后不使相关器械与外部接触保持密封空间，且通过全自动化的清洗灭菌就逐渐成为重要课题。
同时，在上述两个课题的基础上，如何有效抑制成本便于操作又是本领域中的附加课题。
因此，本发明提供一种管式离心机的结构，其目的在于实现完全密封的在线清洗/灭菌，具体而言，自转鼓取下物料后重新将转鼓安装于离心机内后，实现在完全密封的环境下进行清洗灭菌，并持续保持该密封状态直至下一次使用该离心机，从而确保离心机(特别是转鼓)内完全不接触外界，形成完整的无菌状态。
发明内容
发明要解决的问题：
本发明有鉴于上述问题，提供了一种实现可自动可半自动地在完全密封状态下进行高温清洗灭菌的在线灭菌管式离心机。
解决问题的手段：
本发明所涉及的在线灭菌管式离心机的第一实施方式，其是包括：通过旋转离心力进行物液分离的转鼓；通过转鼓连接件与所述转鼓连接固定的主轴；以及具有用于支承所述主轴旋转的轴承单元；的管式离心机，其特征在于，所述轴承单元的上方还设置有上表面形成有凹 槽的轴套；所述主轴贯穿该轴套，并在上端侧形成有贯通孔；所述主轴上端侧形成的贯通孔插入有可嵌入所述轴套上表面的凹槽内的插销。
根据上述结构，在离心机进行物液分离时，所述主轴上的插销嵌入所述轴套上表面的凹槽内，从而在所述主轴旋转时，带动所述凹槽及转鼓进行旋转，从而正常运行实现物液分离。而在离心机进行密封灭菌时，将所述转鼓向上抬起一定距离并旋转一定距离(90°以内)，使所述主轴上的插销与所述轴套上表面的凹槽错位，从而使所述插销卡止于所述轴套的上表面，此时所述转鼓连接件与所述轴承单元相抵接而形成密封空间。
本发明所涉及的在线灭菌管式离心机的第二实施方式，其是包括：通过旋转离心力进行物液分离的转鼓；通过转鼓连接件与所述转鼓连接固定的主轴；以及具有用于支承所述主轴旋转的轴承单元；的管式离心机，其特征在于，所述转鼓的下方设置有转鼓托盘机构；所述转鼓托盘机构，包括：上表面形成为与所述转鼓下表面啮合形状的转鼓托盘；以及形成于所述转鼓托盘下方的支架；所述转鼓托盘机构通过移动装置可在上下方向进行移动。
根据上述结构，在离心机进行物液分离时，所述转鼓托盘通过移动装置向下移动一定距离，从而在所述主轴旋转时，带动所述转鼓进行旋转而不会与转鼓托盘摩擦，从而正常运行实现物液分离。而在离心机进行密封灭菌时，所述转鼓托盘通过移动装置向上移动一定距离，从而使所述转鼓连接件与所述轴承单元相抵接而形成密封空间。
第二实施方式下，优选的是，所述移动装置为连缸的油压机构或气压机构，或，所述移动装置为设置在支架上的偏心轮。。
根据上述结构，由于转鼓重量较大，因此可以通过机械手段或杠杆原理将所述转鼓向上移动。
上述第一实施方式及第二实施方式下，优选的是，所述转鼓连接件上方设置有密封圈。
根据上述优选结构，可以进一步提高密封效果。
本发明还提供了一种第一实施方式下在线灭菌管式离心机的运行步骤，其特征在于，包括下述步骤：将所述主轴上的插销错开所述轴套上表面的凹槽，使插销卡止在所述主轴上表面。
本发明还提供了一种第二实施方式下在线灭菌管式离心机的运行步骤，其特征在于，包括下述步骤：通过所述转鼓托盘机构将所述转鼓向上托起一定距离。
图1是本发明的在线灭菌管式离心机的立体图；
图2是本发明的十字轴套的主视图；
图3是本发明的十字轴套的运行运行状态的俯视图；
图4是本发明的十字轴套的密封运行状态的俯视图；
图5是本发明的在线灭菌管式离心机的运行状态下的图1中A部放大的示意图；
图6是本发明的在线灭菌管式离心机的密封状态下的图1中A部放大的示意图；
图7是本发明的在线灭菌管式离心机的安装有转鼓托盘机构状态下的立体图；
图8是本发明的在线灭菌管式离心机的图1中B部放大的示意图。
以下，通过附图，对本发明的在线灭菌管式离心机的结构进行说明。
如图1所示，本发明的在线灭菌管式离心机，包括：转鼓1、通过转鼓连接件4与转鼓1上端连接固定的主轴3、用于支撑主轴3旋转的轴承单元2、以及位于转鼓1下方用于支撑转鼓1的下阻尼、贯通下阻尼并延伸至转鼓1下端开口一定距离的输料管等。
现有技术中，转鼓1由于其结构限制，无法实现密封状态，从而无法对转鼓1进行灭菌，或进行灭菌后也无法实现密封保存灭菌状态。而本发明提供了下述两种静密封方法，从而可以使转鼓1以安装在壳体内的状态下通过外部操作直接进行清洗灭菌，并且灭菌完成后可以保持灭菌状态直至下一次进行物料分离运行。
实现这种在线(转鼓1安装在壳体内状态下)灭菌技术的实现，可以适用于对某些特定药物进行无菌物液分离的技术需求。
以下，通过相关附图分别对着两种静密封状态进行详细说明。
《机头密封结构》
本发明的第一种静密封结构，主要改良部位为图1中A区所示部分。其通过在转鼓轴承单元2上增设十字轴套5，实现管式离心机的静密封状态。
如图2所示，该十字轴套5，形成为大致筒状，其中心位置形成有供主轴3贯通的开孔。
十字轴套5的上表面形成有呈十字交错的凹槽。
主轴3的上端位置处形成有插销通孔31，通过该开口贯穿设置有一字插销32。
主轴3上端贯穿的一字插销32可与十字轴套4上表面的凹槽相啮合。
如上所述，主轴3通过转鼓连接件4与转鼓1连接固定。
因此，当管式离心机进行正常的物料分离时，主轴3上的一字插销32嵌入十字轴套5上的凹槽内，形成为如图3所示的状态。此时，转鼓连接套4与轴承单元2，如图5所 示，两者并没有接触而影响转鼓1的旋转。从而，在主轴1接收电机动力而旋转时，通过一字插销32的啮合带动十字轴套5一并旋转，而其下端通过转鼓连接件4带动转鼓1一并旋转进行物液分离。
而，当管式离心机进行密封灭菌时，将主轴3抬起一定距离，并手动/电动旋转主轴3一定距离，从而使主轴3上一字插销32与十字轴套5上的凹槽错开，此时放开主轴3时，由于一字插销32未嵌入十字轴套的凹槽内，从而卡止在十字轴套5的上表面。
此时，转鼓连接套4与轴承单元2，如图6所示那样，相互接触从而使转鼓形成为密封状态，并由于一字插销32的关系转鼓1卡止于该位置。从而，通过转鼓1下端的输料管向转鼓内输入高温水或其他灭菌药剂。
并且，转鼓内完成灭菌后，不需要放下主轴3，而是继续保持转鼓1的密封状态，直至下一次转鼓1的运行。当然，也可以是直接在下一次转鼓1运行前再进行灭菌亦可。
但是，上述说明中，本实施例下机头密封结构采用了十字轴套5，其上表面形成有相互交错的十字型凹槽，但本发明并不仅限于此，也可以在该“十字轴套5”的上表面仅形成有一字凹槽。
但是，上述说明中，本实施例下机头密封结构采用了十字轴套5，其上表面形成有相互交错的十字型凹槽，但本发明并不仅限于此，也可以在该“十字轴套5”的上表面仅形成有一字凹槽。
另外，作为本发明的优选结构，如图5图6所示，可以在轴承单元2的下表面中与转鼓连接套4相接触处设置第一密封圈6，从而进一步提高密封效果。
进一步优选的，在图6中所示位置处，可以进一步设置第二密封圈7和第三密封圈8，从而进一步提高密封效果。
《底部密封结构》
本发明提供的第二种静密封结构，主要改良部位为图1中B区所示部分。其通过转鼓1下方的转鼓托盘机构7，实现管式离心机的静密封状态。
如图7图8所示，该转鼓托盘机构7，包括：转鼓托盘71以及形成与转鼓托盘71下方的三个支架72。
转鼓托盘71形成为大致圆盘形状，其中心凹陷贯通，且凹陷面可以与转鼓1的底部想捏和。另，转鼓托盘71中靠近壳体开门方向处形成有开口，从而方便转鼓1的放入。
支架72形成为棍(棒)状，其用于支撑转鼓托盘71，其贯穿壳体下端的板件，并在左右两根支架72上设置有偏心轮，从而实现支架72的升降。
因此，当管式离心机进行正常的物料分离时，通过支架72上的偏心轮降低转鼓托盘71。此时，转鼓连接套4与轴承单元2，如图5所示，两者并没有接触而影响转鼓1的旋转。
而，当管式离心机进行密封灭菌时，通过支架72上的偏心轮抬起转鼓托盘71。此时，由于转鼓1被托起，转鼓连接套4与轴承单元2，如图6所示那样，相互接触从而使转鼓形成为密封状态，从而，通过转鼓1下端的输料管向转鼓内输入高温水或其他灭菌药剂。
上述说明中，作为本发明的一种实施方式，转鼓托盘71通过支架72上的偏心轮实现其上下方向的升降。但也可以采用连缸的油压或气压机构，通过向油压或气压机构内施加或释放压力，实现转鼓托盘71的上下方向的升降。
同样地，作为该实施方式的一种优选结构，如图5图6所示，可以在轴承单元2的下表面中与转鼓连接套4相接触处设置一密封圈6，从而进一步提高密封效果。
上述说明中，对本发明的发明宗旨进行了详细说明，但该说明仅例举了本发明的一种较优状态的实施方式，本发明的实施方式并不仅限于上述说明的内容，在不违反本发明的发明宗旨的情况下，其相关的部件和/或结构的增加、减少、简单置换都应当归属于本发明的保护范围内。
标记符号：
1 转鼓；
2 轴承单元；
3 主轴；
31 插销通孔；
32 一字插销；
4 转鼓连接件；
5 十字轴套；
6 第一密封圈；
7 转鼓托盘机构；
71 转鼓托盘；
72 支架；
8 第二密封圈；
9 第三密封圈。
Claims (7)
- 一种在线灭菌管式离心机，其是包括：通过旋转离心力进行物液分离的转鼓；通过转鼓连接件与所述转鼓连接固定的主轴；以及具有用于支承所述主轴旋转的轴承单元；的管式离心机，其特征在于，所述轴承单元的上方还设置有上表面形成有凹槽的轴套；所述主轴贯穿该轴套，并在上端侧形成有贯通孔；所述主轴上端侧形成的贯通孔插入有可嵌入所述轴套上表面的凹槽内的插销。
- 一种在线灭菌管式离心机，其是包括：通过旋转离心力进行物液分离的转鼓；通过转鼓连接件与所述转鼓连接固定的主轴；以及具有用于支承所述主轴旋转的轴承单元；的管式离心机，其特征在于，所述转鼓的下方设置有转鼓托盘机构；所述转鼓托盘机构，包括：上表面形成为与所述转鼓下表面啮合形状的转鼓托盘；以及形成于所述转鼓托盘下方的支架；所述转鼓托盘机构通过移动装置可在上下方向进行移动。
- 根据权利要求2所述的在线灭菌管式离心机，其特征在于，所述移动装置为连缸的油压机构或气压机构。
- 根据权利要求2所述的在线灭菌管式离心机，其特征在于，所述移动装置为设置在支架上的偏心轮。
- 根据权利要求1至4中任意一项所述的在线灭菌管式离心机，其特征在于，所述转鼓连接件上方设置有密封圈。
- 一种在线灭菌管式离心机的运行步骤，其特征在于：根据权利要求1所述的在线灭菌管式离心机，执行下述步骤：将所述主轴上的插销错开所述轴套上表面的凹槽，使插销卡止在所述主轴上表面。
- 一种在线灭菌管式离心机的运行步骤，其特征在于：根据权利要求3所述的在线灭菌管式离心机，执行下述步骤：通过所述转鼓托盘机构将所述转鼓向上托起一定距离，并将所述主轴上的插销错开所述轴套 上表面的凹槽，从而使所述插销卡止于所述主轴上表面。
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| JP2015104700A (ja) * | 2013-11-29 | 2015-06-08 | 日立工機株式会社 | 遠心機及びその制御方法 |
| CN206121937U (zh) * | 2016-10-24 | 2017-04-26 | 中逸安科生物技术股份有限公司 | 一种具有自动清洗消毒功能的管式分离机 |
| CN109985733A (zh) * | 2019-05-10 | 2019-07-09 | 辽宁贝克瑞生物科技有限公司 | 一种管式离心机 |
| CN209577047U (zh) * | 2019-03-06 | 2019-11-05 | 上海洁维生物工程有限公司 | 一种管式离心机 |
| CN110756339A (zh) * | 2019-11-27 | 2020-02-07 | 上海知正离心机有限公司 | 在线灭菌管式离心机以及优化系统和使用步骤 |
| CN211303440U (zh) * | 2019-11-27 | 2020-08-21 | 上海知正离心机有限公司 | 在线灭菌管式离心机 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2015104700A (ja) * | 2013-11-29 | 2015-06-08 | 日立工機株式会社 | 遠心機及びその制御方法 |
| CN206121937U (zh) * | 2016-10-24 | 2017-04-26 | 中逸安科生物技术股份有限公司 | 一种具有自动清洗消毒功能的管式分离机 |
| CN209577047U (zh) * | 2019-03-06 | 2019-11-05 | 上海洁维生物工程有限公司 | 一种管式离心机 |
| CN109985733A (zh) * | 2019-05-10 | 2019-07-09 | 辽宁贝克瑞生物科技有限公司 | 一种管式离心机 |
| CN110756339A (zh) * | 2019-11-27 | 2020-02-07 | 上海知正离心机有限公司 | 在线灭菌管式离心机以及优化系统和使用步骤 |
| CN211303440U (zh) * | 2019-11-27 | 2020-08-21 | 上海知正离心机有限公司 | 在线灭菌管式离心机 |
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