WO2021098658A1

WO2021098658A1 - Positioning arm with cranial drill

Info

Publication number: WO2021098658A1
Application number: PCT/CN2020/129182
Authority: WO
Inventors: 吕泽中; 詹阳
Original assignee: 中国科学院深圳先进技术研究院
Priority date: 2019-11-18
Filing date: 2020-11-16
Publication date: 2021-05-27
Also published as: CN112807122B; CN112807122A

Abstract

Disclosed is a positioning arm (22) with a cranial drill (1) for application in a brain region experiment of an animal. The positioning arm comprises: the cranial drill (1) and a positioning and fixing assembly (2) for positioning, wherein the positioning and fixing assembly (2) is provided with an elastic connection sleeve (21), and the cranial drill (1) is detachably connected to the positioning and fixing assembly (2) in such a way that the cranial drill (1) is sleeved by the connection sleeve (21) and fastened by the connection sleeve (21). The positioning arm (22) can be used in a head experiment surgery procedure of a rat or a mouse, allows drilling to be directly carried out after positioning, the positioning arm (22) does not need to be removed and manual marking is not required, such that the entire process is convenient, accurate and rapid, same is easy in terms of operation and the time for positioning and drilling in surgery can be effectively reduced. The positioning arm has a strong universality and can be mounted on most rat and mouse brain stereotaxic apparatuses in the market for use.

Description

Positioning arm with cranial drill

Technical field

The invention relates to the field of experimental surgical devices, in particular to a positioning arm with a cranial drill.

Background technique

In experimental operations on the head of rats and mice, it is necessary to perform positioning and drilling on the head of the mouse due to the need to embed optical fibers, electrodes, drug tubes and other devices and perform drug injection.

However, the current positioning and drilling are separated. The positioning function is realized by using the positioning arm in the laboratory. After the positioning arm is used for positioning, it is necessary to combine other methods or means to mark the position of the positioning. ；

After marking, the positioning arm needs to be removed, and then the cranial drill is used to drill the hole based on the position of the mark, which leads to the complexity of the entire experimental operation, and the position of the drill hole and the position of the mark cannot be completely overlapped. , It is very easy to cause the problem of inaccurate drilling position.

Therefore, there is a need for a better solution to solve this problem.

technical problem

In view of the defects in the prior art, the present invention proposes a positioning arm with a cranial drill. By combining the positioning arm with the cranial drill, the positioning arm of this scheme can be used for experimental surgery on the head of rats and mice During the process, positioning and drilling are completed at the same time, without manual marking, the entire process is convenient, accurate and rapid; and the operation is simple, which can effectively shorten the time for surgical positioning and drilling; it is versatile and can be installed in most large mouse brains on the market. Use on the locator.

Technical solutions

Specifically, the present invention proposes the following specific embodiments:

The embodiment of the present invention discloses a positioning arm with a cranial drill, which is applied to an animal brain area experiment, including: a cranial drill, a positioning and fixing component for positioning; wherein the positioning and fixing component is provided with an elastic Connecting sleeve; the cranial drill is sleeved in the connecting sleeve and fastened by the connecting sleeve to achieve a detachable connection with the positioning and fixing assembly.

In a specific embodiment, the cranial drill includes a driving rod and a drill bit; wherein the driving rod is detachably connected to the drill bit to drive the drill bit to rotate.

In a specific embodiment, the driving rod includes:

Drill connecting rod, guide tube, main motor, shell, sliding seat, internal threaded tube, screw, feed motor, controller, guide rail;

The drill bit connecting rod is detachably connected to the drill bit;

The front end of the housing is provided with the guide tube; the drill bit connecting rod is accommodated in the guide tube;

The rear end of the drill bit connecting rod is connected to the motor shaft of the main motor; the rear end of the main motor is connected to the front side of the sliding seat;

A plurality of guide rails are provided in the casing along the length direction; the sliding seat is slidably connected with the guide rail;

The rear side of the sliding seat is connected with a hollow threaded tube; the inner side of the threaded tube is provided with an internal thread;

The rear end of the housing is provided with a feed motor, the front end of the feed motor is provided with a screw, and the screw is connected by fitting with the internal thread of the threaded tube, and the rear of the housing is also provided There are controllers for respectively connecting and respectively controlling the main motor and the feed motor; the controller is provided with a power cord.

In a specific embodiment, the outer surface of the housing of the drive rod is provided with anti-slip patterns.

In a specific embodiment, the shell is a metal shell or a polymer shell.

In a specific embodiment, the shape of the housing is cylindrical.

In a specific embodiment, the positioning and fixing assembly further includes: a positioning arm and a fastening screw; wherein a fixing groove is provided in the positioning arm; a through fastening hole is also provided on one side of the fixing groove The inner wall of the fastening hole is provided with an internal thread;

Both ends of the connecting sleeve are embedded in the fixing groove of the positioning arm;

The inner end of the fastening screw rotates in the internal thread of the fastening hole to realize the opening and closing of the two ends of the connecting sleeve, so as to realize the tightness adjustment of the connecting sleeve.

In a specific embodiment, the outer end of the fastening screw is provided with anti-slip patterns.

In a specific embodiment, the outer end of the fastening screw is cylindrical.

In a specific embodiment, the outer end of the fastening screw is provided with anti-slip teeth.

Beneficial effect

Therefore, the embodiment of the present invention discloses a positioning arm with a cranial drill, which is applied to an animal brain area experiment, including: a cranial drill, a positioning and fixing assembly for positioning; wherein the positioning and fixing assembly is provided with A flexible connecting sleeve; the cranial drill is sleeved in the connecting sleeve and fastened by the connecting sleeve to realize a detachable connection with the positioning and fixing assembly. Through the positioning arm of this scheme, it is possible to drill directly after positioning during the experimental operation on the head of rats and mice, without removing the positioning arm, without manually marking, the whole process is convenient, accurate and rapid; and the operation is simple, which can effectively shorten the surgical positioning Drilling time; strong versatility, can be installed on the vast majority of mouse brain stereotaxic devices on the market.

Description of the drawings

Figure 1 is a front view of a positioning arm with a cranial drill proposed by an embodiment of the present invention;

Figure 2 is a side view of a positioning arm with a cranial drill proposed by an embodiment of the present invention;

Figure 3 is a top view of a positioning arm with a cranial drill according to an embodiment of the present invention;

Fig. 4 is a schematic structural diagram of a driving rod in a positioning arm with a cranial drill proposed in an embodiment of the present invention.

illustration:

1- cranial drill;

11-driving rod;

111-drill connecting rod; 112-guide pipe;

113-main motor; 1311-motor shaft;

114-housing; 115-sliding seat; 116-internally threaded tube; 117-screw;

118-feed motor; 119-controller; 110-rail;

12-Drill bit; 13-Power cord;

2- Positioning and fixing components;

21-connecting sleeve; 22-positioning arm; 23-fastening screw.

The best mode of the present invention

Hereinafter, various embodiments of the present disclosure will be described more fully. The present disclosure may have various embodiments, and adjustments and changes may be made therein. However, it should be understood that there is no intention to limit the various embodiments of the present disclosure to the specific embodiments disclosed herein, but the present disclosure should be understood to cover those falling within the spirit and scope of the various embodiments of the present disclosure All adjustments, equivalents and/or alternatives.

The terms used in the various embodiments of the present disclosure are only used for the purpose of describing specific embodiments and are not intended to limit the various embodiments of the present disclosure. As used herein, the singular form is intended to also include the plural form, unless the context clearly dictates otherwise. Unless otherwise defined, all terms (including technical and scientific terms) used herein have the same meaning as commonly understood by those of ordinary skill in the art to which various embodiments of the present disclosure belong. The terms (such as those defined in commonly used dictionaries) will be interpreted as having the same meaning as the contextual meaning in the relevant technical field and will not be interpreted as having idealized or overly formal meanings, Unless clearly defined in various embodiments of the present disclosure.

Example

The embodiment of the present invention discloses a positioning arm with a cranial drill, which is applied to an animal brain area experiment, as shown in Figures 1-3, including: a cranial drill 1, a positioning and fixing assembly 2 for positioning; wherein, The positioning and fixing component is provided with a tightenable connecting sleeve 21; the cranial drill is sleeved in the connecting sleeve and fastened by the connecting sleeve to realize a detachable connection with the positioning and fixing component.

Specifically, the positioning arm of this solution is combined with a cranial drill, which can drill directly after positioning during the experimental operation of the head of rats and mice, without removing the positioning arm, so that the positioning position and the drilling position are 100% coincident, so that the drill The hole position is accurate, and the operation is convenient, accurate and quick. And it has strong versatility and can be installed on most stereotaxic devices on the market.

The present invention combines the positioning arm with the cranial drill, so that the experimental operation process of the head of rats and mice can be used.

In a specific embodiment, as shown in Figs. 1-2, the cranial drill includes: a driving rod 11 and a drill bit 12; wherein the driving rod is detachably connected to the drill bit to drive the drill bit to rotate.

Specifically, since the drive rod and the drill bit are connected in a detachable manner, the drill bit is of a detachable and replaceable type, which facilitates the replacement and maintenance of the drill bit model.

In a specific embodiment, as shown in FIG. 4, the driving rod 11 includes:

The drill bit connecting rod is detachably connected to the drill bit;

In this way, the power cord supplies power to the main motor and the feed motor in the entire drive rod. Under the control of the controller, the main motor and/or the feed motor are turned on or off to drive the drill bit to rotate to realize the drilling required for the experiment. operating. In the actual operation process, the feed motor can also be controlled to control the depth of drilling.

In a specific embodiment, in order to better hold the driving rod, the outer surface of the housing of the driving rod is provided with anti-slip patterns.

The specific anti-skid pattern may be a striped pattern, a diamond pattern or a hob texture, etc.

In a specific embodiment, in order to ensure sufficient structural strength, the shell is a metal shell or a polymer shell.

In a specific embodiment, the shape of the housing is cylindrical. Of course, the specific shape can also adopt other shapes, such as a polygonal body and the like, a rectangular parallelepiped and the like.

In a specific embodiment, as shown in Figure 1-2, in order to facilitate the condition of the tightness of the connecting sleeve, that is, the degree of fixation of the sleeve on the drive rod, the positioning and fixing assembly further includes: a positioning arm, a fastening Screws; wherein a fixing groove is provided in the positioning arm; one side of the fixing groove is also provided with a through fastening hole; the inner wall of the fastening hole is provided with an internal thread;

In a specific embodiment, in order to better rotate the fastening screw and facilitate the tightening or loosening of the fastening screw, the outer end of the fastening screw is provided with anti-slip patterns.

In a specific embodiment, the outer end of the fastening screw is cylindrical.

In a specific embodiment, in order to make the tightening and loosening of the fastening screw more convenient and easy to receive force, the outer end of the fastening screw is provided with anti-slip teeth.

Those skilled in the art can understand that the accompanying drawings are only schematic diagrams of preferred implementation scenarios, and the modules or processes in the accompanying drawings are not necessarily necessary for implementing the present invention.

Those skilled in the art can understand that the modules in the device in the implementation scenario can be distributed in the device in the implementation scenario according to the description of the implementation scenario, or can be changed to be located in one or more devices different from the implementation scenario. The modules of the above implementation scenarios can be combined into one module or further divided into multiple sub-modules.

The above-mentioned serial numbers of the present invention are only for description, and do not represent the pros and cons of implementation scenarios.

The above disclosures are only a few specific implementation scenarios of the present invention, but the present invention is not limited to these, and any changes that can be thought of by those skilled in the art should fall into the protection scope of the present invention.

Claims

A positioning arm with a cranial drill, which is characterized in that it is applied to an animal brain area experiment and includes: a cranial drill, a positioning and fixing component for positioning; wherein the positioning and fixing component is provided with a flexible connecting sleeve The cranial drill is sleeved in the connecting sleeve and fastened by the connecting sleeve to achieve a detachable connection with the positioning and fixing assembly.
The positioning arm with a cranial drill according to claim 1, wherein the cranial drill comprises: a driving rod and a drill bit; wherein the driving rod is detachably connected to the drill bit to drive the drill bit Rotate.
The positioning arm with a cranial drill according to claim 2, wherein the driving rod comprises:

Drill connecting rod, guide tube, main motor, shell, sliding seat, internal threaded tube, screw, feed motor, controller, guide rail;

The drill bit connecting rod is detachably connected to the drill bit;

The front end of the housing is provided with the guide tube; the drill bit connecting rod is accommodated in the guide tube;

The rear end of the drill bit connecting rod is connected to the motor shaft of the main motor; the rear end of the main motor is connected to the front side of the sliding seat;

A plurality of guide rails are provided in the casing along the length direction; the sliding seat is slidably connected with the guide rail;

The rear side of the sliding seat is connected with a hollow threaded tube; the inner side of the threaded tube is provided with an internal thread;

The rear end of the housing is provided with a feed motor, the front end of the feed motor is provided with a screw, and the screw is connected by fitting with the internal thread of the threaded tube, and the rear of the housing is also provided There are controllers for respectively connecting and respectively controlling the main motor and the feed motor; the controller is provided with a power cord.
The positioning arm with a cranial drill according to claim 3, wherein the outer surface of the housing of the driving rod is provided with anti-slip patterns.
The positioning arm with a cranial drill according to claim 3 or 4, wherein the shell is a metal shell or a polymer shell.
The positioning arm with a cranial drill according to claim 3 or 4, wherein the shape of the shell is cylindrical.
The positioning arm with a cranial drill according to claim 1, wherein the positioning and fixing assembly further comprises: a positioning arm and a fastening screw; wherein a fixing groove is provided in the positioning arm; One side of the fixing groove is also provided with a through fastening hole; the inner wall of the fastening hole is provided with an internal thread;

Both ends of the connecting sleeve are embedded in the fixing groove of the positioning arm;

The inner end of the fastening screw rotates in the internal thread of the fastening hole to realize the opening and closing of the two ends of the connecting sleeve, so as to realize the tightness adjustment of the connecting sleeve.
The positioning arm with a cranial drill according to claim 7, wherein the outer end of the fastening screw is provided with anti-skid patterns.
The positioning arm with a cranial drill according to claim 7 or 8, wherein the outer end of the fastening screw is cylindrical.
The positioning arm with a cranial drill according to claim 7, wherein the outer end of the fastening screw is provided with anti-slip teeth.