WO2021072521A1 - Composition, production method and use of nutritive sweeteners and blends - Google Patents

Composition, production method and use of nutritive sweeteners and blends Download PDF

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Publication number
WO2021072521A1
WO2021072521A1 PCT/BR2020/050411 BR2020050411W WO2021072521A1 WO 2021072521 A1 WO2021072521 A1 WO 2021072521A1 BR 2020050411 W BR2020050411 W BR 2020050411W WO 2021072521 A1 WO2021072521 A1 WO 2021072521A1
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sweetener
syrup
sucrose
sweeteners
added
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PCT/BR2020/050411
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French (fr)
Portuguese (pt)
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Ivo RISCHBIETER
Ronaldo BIONDO
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Rischbieter Ivo
Biondo Ronaldo
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Publication of WO2021072521A1 publication Critical patent/WO2021072521A1/en

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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30Artificial sweetening agents
    • A23L27/31Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30Artificial sweetening agents
    • A23L27/33Artificial sweetening agents containing sugars or derivatives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15Vitamins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/16Inorganic salts, minerals or trace elements
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/20Reducing nutritive value; Dietetic products with reduced nutritive value
    • A23L33/21Addition of substantially indigestible substances, e.g. dietary fibres
    • CCHEMISTRY; METALLURGY
    • C13SUGAR INDUSTRY
    • C13KSACCHARIDES OBTAINED FROM NATURAL SOURCES OR BY HYDROLYSIS OF NATURALLY OCCURRING DISACCHARIDES, OLIGOSACCHARIDES OR POLYSACCHARIDES
    • C13K3/00Invert sugar; Separation of glucose or fructose from invert sugar

Definitions

  • the present invention relates to the production of natural sweeteners and blends based on inverted liquid sugars by enzymatic or chemical route, containing optional addition of nutritious and functional components always seeking the healthiness and functionality of the product.
  • the sweetener of the present invention refers to a product of plant origin, being produced based on inverted sucrose, preferably by means of enzymatic catalysis, by the same enzyme used by bees in the production of honey, dark VHP or VVHP sugars or Demerara or Mascavo rich in minerals, vitamins and natural antioxidants with great nutritional and pharmacological appeal and also blends of inverted sugar with natural sweeteners, such as Estevia, and optionally with sweeteners, always seeking to exalt the sweetness maintaining the flavor and characteristics of the sugar in the product with as few calories as possible.
  • sweetener of the present invention can be consumed directly or in the production of other food, pharmaceutical, nutraceutical or cosmetic products, not being limited only to these.
  • the sweetener also has characteristics of sugar flavor, shelf life, caramelization, solids, depression freezing point and texture very close to that of sucrose, which allows a wide possibility of substituting the use of sucrose, glucose or fructose while maintaining the characteristics of the product with gain in the reduction of the amount of calories being an important alternative that with regard to calories remaining in terms of reduction of the same among the natural / artificial sweeteners and sugars in general.
  • a new sweetness option with natural flavor, organic or not, not yet available on the market BACKGROUND OF THE INVENTION [003] Human beings have always added sweeteners to their diet. The first sweetener to be used was honey, which can be confirmed by reports in ancient cultures such as Chinese and Greek.
  • Tree sap was also widely used, Canada's maple sap being an example, used to this day.
  • Honey was later replaced by sucrose originally obtained from sugar cane.
  • the preference for sweet taste is innate in humans. This can already be seen in newborns, who calm down with drops of glycated serum.
  • Sweeteners are products specifically developed to give a sweet taste to food and beverages, with sucrose (cane or beet sugar) as the main example.
  • sucrose cane or beet sugar
  • sugar is widely used for its preservative, antioxidant and antimicrobial effect and is sometimes replaced by sweetening sweeteners
  • BRAZIL ANVISA National Health Surveillance Agency. Resolution - RDC n ° 3 of January 2, 2001
  • Sweeteners Limitations and Approvals by ANVISA. Available at: http://en.shvoong.com/medicine- and- health / nutrition / 1787176-anvisadecide-limit-usage-two / Accessed: 05 April 2019].
  • sweeteners are chemical substances responsible for the sweet taste and usually have a sweetening power far superior to sucrose, therefore requiring a much smaller amount to obtain the same sweetness, with the advantage of having less or less sweetness. no calories.
  • dietary sweeteners are basically made up of sweeteners and body agents, also called vehicles and are compounds used with the purpose of diluting sweeteners by adding volume to the product [Cesar P. Chemistry Study Portal: Chemistry in the kitchen presents : The sugar. Available at: http://www.profpc.com.br/Qu%C3%ADmica%20na%20Cozinha/A%C3%A7%C 3% BAcar / ado% C3% A7ante_artificial.htm. Accessed on: 05 abr. 2019].
  • Sweeteners can be classified into nutritious and non-nutritive.
  • Nutritional sweeteners include caloric sugars such as sucrose, fructose, dextrose, lactose, maltose, honey, corn syrup, high fructose corn syrup, molasses, inverted sugars, fruit juices concentrated fruits and polyols, also called alcohol sugars, such as sorbitol, mannitol, xylitol and others (called hydrogenated starch hydrolysates) [ADA Reports. Position of the American Dietetic Association: use of nutritive and nonnutritive sweeteners. J Am Diet Assoe; 104 (2): 255-75, 2004. Erratum in: J Am Diet Assoe. 104 (6): 1013, 2004].
  • Non-nutritive sweeteners started to be used during the inter-war period due to the scarcity of sugar. From 1950 on, there was a change in the reason for use: it went from being concerned with cost to reducing calorie intake. They are considered food additives. Despite the intense use of these substances today, in different age groups and in all social strata, there is still a lot of doubt regarding the possible side effects associated with their use.
  • sweeteners Often, people ingest sweeteners without being aware of it. This is because various industrialized foods, such as candies, sweets, chewing gum, juices, soft drinks, toothpastes and medicines contain sweeteners.
  • Sucrose is a disaccharide composed of glucose and fructose and was the main sweetener used in the first half of the last century. Intake ranges from 14 to 60 g / day, averaging 41 g / day, consisting of about 7% to 11% of calories ingested in the USA. Provides 4Kcal / g. [ADA Reports. Position of the American Dietetic Association: use of nutritive and non-nutritive sweeteners. J Am Diet Assoe 104 (2): 255-75, 2004. Erratum in: J Am Diet Assoe 104 (6): 1013, 2004].
  • Fructose is a monosaccharide found mainly in fruits. It is found as a component of high fructose corn syrups. Crystalline fructose is obtained from corn starch through isomerization. Provides 4 Kcal / g. Fructose has been associated in several epidemiological studies such as weight gain, triglycerides, high blood pressure and insulin resistance and increase in uric acid levels. It has sweetening power 1, 7 times in relation to sucrose. It has advantages in relation to glucose and sucrose, because, in addition to being sweeter, it has more solubility than glucose and sucrose. Your metabolism does not depend on insulin. The acceptable daily dose is up to 50g / day [Livesey G, Taylor R. Fructose consumption and consequences for glycation, plasma triacylglycerol, and body weight: meta analyzes and meta-regression models of intervention studies. Am J Clin utr 88 (5): 1419-37, 2008].
  • Glucose which is also a monosaccharide, is found in fruits, vegetables and honey. Absorbed in the small intestine. It does not cause intestinal fermentation. It has less sweetening effect than sucrose. Provides 4Kcal / g [Tumas R, Goastico SSV, Gandolfo AS. Sweeteners. In: Delgado AF, Cardoso AL, Zamberlan P. Sweeteners in basic and advanced nutrology. S ⁇ o Paulo: Manole; 2010].
  • Lactose is milk sugar and is a disaccharide composed of one molecule of glucose and one of galactose. It has a lower sweetening power than sucrose. It can lead to intestinal fermentation in individuals with lactase deficiency.
  • Polyols or sugar alcohols such as sorbitol, mannitol and xylitol have half the sweet taste of sucrose. They are less caloric than sucrose, glucose and fructose and provide between 1, 6 and 2.6 Kcal / g. Sorbitol also has the advantage of stimulating gallbladder motility.
  • polyols have incomplete intestinal absorption, they can lead to diarrheal conditions [ADA Reports. Position of the American Dietetic Association: use of nutritive and non-nutritive sweeteners.
  • Non-nutritive sweeteners are also called intense, low-calorie sweeteners or alternative sweeteners.
  • five non-nutritive sweeteners sacharin, cyclamate, aspartame, acesulfame, sucralose and alitame
  • a non-caloric sugar derived from a plant rebaudiosidio A, Estevia
  • the protein Taumatina are recognized as safe by the FDA [Pepino MY, Bourne C. Non-nutritive sweeteners, energy balance, and glucose homeostasis. Curr Opin Clin Nutr Metab Care 14: 391-5, 2011; Kroger M, Meister K, Kava R. Low-calorie Sweeteners and Other Sugar Substitutes: A Review of the Safety Issues. Comprehensive Reviews in Food Science and Food Safety 5: 35-47, 2006].
  • Saccharin is the oldest and comes from methylanthranilate, a substance that appears naturally in grapes. It was discovered in 1875 by Constantin Fahlberg, from John Flopkins University, while studying the oxidation of sulfonamides (o-toluenesulfanamide), substances obtained from petroleum derivatives [Kroger M, Meister K, Kava R. Low-calorie Sweeteners and Other Sugar Substitutes: A Review of the Safety Issues. Comprehensive Reviews in Food Science and Food Safety 5: 35-47, 2006]. It is about 300 times sweeter than sucrose, heat-stable and non-cardiogenic. It has a long half-life, but has a residual metallic / bitter taste.
  • saccharin is approved in more than 90 countries and is widely used in many medicines and foods [Fatibello-Filho O, Vieira ID, Gouveia ST, Calafatti AS, Guarita-Santos AJM. Artificial sweeteners. Qu ⁇ mica Nova 19: 248- 260, 1996].
  • Cyclamate is composed of cyclohexyl-sufamic acid and was discovered in 1937 by Michael Sveda, from the University of Illinois. The discovery of its sweet taste property was attributed to accidental contamination of cigarettes with a cyclohexylamine derivative. Its sweetening power is small when compared to other sweeteners, only 30 times greater than that of sucrose. It is used in combination with saccharin, combining the high sweetening power of saccharin with the absence of residual cyclamate flavor. The FDA has banned it since 1970 and because of the existence of studies showing an association with cancer. Until then, it was believed that its absorption by the organism was slow and partial and that it was eliminated quickly and unchanged, with minimal toxic action [Collings AJ.
  • Acesulfame K or acesulfame potassium was discovered in 1967 in Germany. It is an organic salt consisting of carbon, nitrogen, oxygen, hydrogen, sulfur and potassium. It is about 200 times sweeter than sucrose, having synergism with other sweeteners. It has heat stability and can be used in cooking and baking. It has no prolonged aftertaste, but this can happen in high doses [Kroger M, Meister K, Kava R. Low-calorie Sweeteners and Other Sugar Substitutes: A Review of the Safety Issues. Comprehensive Reviews in Food Science and Food Safety 5: 35-47, 2006; Cantarelli M, Pellerano RG, Marchevsky EJ, Camina JM.
  • Sucralose was synthesized in a laboratory at the University of London in 1976. It is a derivative of sucrose, with replacement of three hydroxyl groups by chlorine, having little absorption, and the small amount absorbed is not metabolized for energy production . After several studies, sucralose proved to be safe, not being associated with the development of cancer, causing no genetic alterations, birth defects, neurological damage or any other metabolic alteration, even at a dose above 500 mg / kg / day. It does not cause an insulin response and several studies have shown that it is safe for the environment, being biodegradable. It is about 400 to 800 times sweeter than sucrose. Due to its solubility in water and stability, sucralose can be used in various industrialized foods and drinks.
  • the maximum acceptable intake is about 15 mg / kg / day [ADA Reports. Position of the American Dietetic Association: use of nutritive and non-nutritive sweeteners. J Am Diet Assoe 104 (2): 255-75, 2004. Erratum in: J Am Diet Assoe 104 (6): 1013, 2004].
  • Alitame is formed by two amino acids (aspartic acid and alanine) and a starch, which is the main responsible for the high sweetening power, about 2,000 times greater than sucrose. It has stability at high temperatures and wide pH variations and is highly soluble in water. Several studies show its safety, even at a dose above 100 mg / kg / day, a dose about 300 times higher than the usual dose for chronic users [ADA Reports. Position of the American Dietetic Association: use of nutritive and non-nutritive sweeteners. J Am Diet Assoe 104 (2): 255-75, 2004. Erratum in: J Am Diet Assoe 104 (6): 1013, 2004].
  • Stevioside is obtained from the plant Estevia rebaudiana Bertoni, belonging to the Compositae family, originally from the Americas, where it is used as a medicinal plant in the control of diabetes. It is a temolabile substance, non-carcinogenic and which is not metabolized by the body. It has about 300 times the sweetening power compared to sucrose. The leaves of this plant have been used for centuries by the native population as a sweetener. The substances associated with the sweet taste are nine glycosides, called steviole glycosides. Depending on cultivation and growth techniques, the amount of these glycosides varies from 4% to 20% dry weight. Stevioside and rebaudioside A are the most abundant among the nine glycosides.
  • Rebaudioside A is considered to have the best organoleptic sweetener properties and has the least residual flavor.
  • Several studies have shown the toxicological safety of these substances. As a result, extracts containing steviosides are released in Japan, Brazil, South Korea, Argentina and Paraguay and used as dietary supplements in the USA. They have not yet been released in the European Union, but have received GRAS recognition, recognized as safe in the USA since 2008.
  • the FAO / WHO Committee for Food Additives suggests an acceptable daily intake of up to 4mg / kg [ADA Reports. Position of the American Dietetic Association: use of nutritive and non- nutritive sweeteners. J Am Diet Assoe 104 (2): 255-75, 2004. Erratum in: J Am Diet Assoe 104 (6): 1013, 2004].
  • Thaumatin is a long-chain vegetable protein naturally contained in the Katemfe fruit. This protein has unique properties and benefits: it is the sweetest substance in all of Nature (on average 3,000 times sweeter than sugar), a potent flavor / aroma enhancer and has the ability to mask unwanted residual flavors (such as example, bitter and metallic) of numerous substances, including artificial sweeteners (cyclamate, saccharin, acesulfame etc.), stevia, soy, minerals, vitamins, substances for pharmaceutical / medical use, among others.
  • artificial sweeteners cyclamate, saccharin, acesulfame etc.
  • stevia soy
  • minerals soy
  • vitamins vitamins, substances for pharmaceutical / medical use, among others.
  • thaumatin is harmless to human health. Therefore, it can be consumed by everyone, including diabetics, phenylketonurics, pregnant women, etc., without restrictions to any population group.
  • thaumatin is approved as GRAS (Generally Recognized As Safe ”) in the United States and is approved in Europe, Canada, Japan and many other countries.
  • thaumatin consists of a 100% natural and stable sweetener.
  • Thaumatin is the only high intensity sweetener approved with no maximum use limit (quantum satis) by ANVISA [Daniell WF. Katemfe, or the spontaneous fruit of Soudan. Pharm J 14, 158, 1855; Eaton KK, Daniel JW, Snodin DJ, Higginbotham JD, Stanworth DR, Al-Mosawie T.
  • Thaumatin protein Assessment in man for oal allergenicity on challenge testing, 1981; Higginbotham JD, Snodin DJ, Eaton KK, Daniel JW. Safety Evaluation of Thaumatin. Fd. Chem. Toxicol., 21, 815-823, 1983].
  • Advantame is a new artificial sweetener developed by the company Ajinomoto and is extremely potent, being 20,000 times sweeter than sucrose and 100 times sweeter than aspartame. It is derived from aspartame, being a dipeptide sweetener composed of aspartic acid, phenylalanine and vanillin. It has a sweet taste close to that of sugar, without residual taste. It is stable in dry conditions and in aqueous form the stability is similar to aspartame. In 2009, the FDA was approved for use in the United States. It has zero calories [Bishay IE, Bursey RG. Advantame. In: O'Brien Nabors L. Alternative sweeteners. 4th ed. Boca Raton, Fl: CRC; 2011].
  • JECFA The committee that evaluates additives is the FAO / WHO Committee of Experts in Food Additives (JECFA), which is formed by an international group of experts who are selected mainly for their capacity and technical experience. These experts meet regularly and discuss technical and scientific issues, establish specifications for the identity and purity of additives, assess toxicological data and recommend, where appropriate, acceptable daily intakes (IDA) for people, subject to regular reviews [IPCS (INTERNATION PROGRAMME ON CHEMICAL SAFETY), 2011. About IPCS INCHEM. Available at: ⁇ http://www.inchem.org/pages/about.html>. Accessed in May 2019].
  • IDA is an estimate of the amount of an additive that can be ingested daily, and for life, by man, without appreciable health risk. It is expressed in milligrams of additive per kilogram of body weight (mg / kg bw) [CAC (Codex Alimentarius Commission), 1989. Report of the twenty-first session of the Codex Committee on Food Additives and Contaminants. Codex Alimentarius Commission, Food and Agriculture Organization of the United Nations, ALINORM 89 / 12A, Rome, 1989].
  • the potential intake of an additive refers to its likely intake, resulting from the maximum limits allowed for its use in different foods and beverages and the eating habits of the population.
  • Table 1 Acceptable Daily Intake Values (IDA) for artificial sweeteners allowed in Brazil established by the FAO / WHO Committee of Experts in Food Additives [JECFA - Joint Expert Committee on Food Additives and Contaminants, Sixty-ninth meeting, Rome, Italy, 17-26 June 2008]. Evaluation of the consumption of food and sweeteners
  • Eating habits are closely related to cultural, anthropological, socioeconomic and psychological aspects that involve people's environment [Fisberg RM, Marchioni DML, Colucci ACA. Evaluation of food consumption and nutrient intake in clinical practice. Arq Bras Endocrinol Metabol 53, n.5, 2009].
  • sweeteners in food, drinks and table sweeteners has grown a lot.
  • the combination of them has several advantages, such as the increase in sweetness stability and synergism effect, increasing the sweetening power.
  • the combination brings benefits to industries, such as improving the quality of sweetness (combinations can reduce the undesirable effects of some sweeteners) and obtaining sweeteners with characteristics similar to sucrose
  • dietary sweeteners are used without much discretion, and many of their users mainly aim at vanity more than their real needs. These are usually used on their own initiative, sometimes by random indications or simply for practical use. The minority uses it with medical or nutritionist recommendations.
  • the present invention provides a new method of producing sweeteners, obtaining a formulation that preserves the taste of sugar, but with calorie reduction, starting from inverted sucrose and blends with preferably natural or synthetic sweeteners.
  • a composition with uniform quality is presented, as its composition depends on a source of sucrose and sweeteners, which guarantees the consumer the safety of a food supplement of controlled origin, ensuring a food in line with the specific demands of each type of consumer.
  • the present invention presents a process for the production of a sweetener, preferably starting from the raw material sucrose, that is, inverted sucrose, preferably by means of enzymes (not chemically) obtaining a syrup with equimolar parts glucose and fructose and low concentration of sucrose and blends with different types of sweeteners.
  • the present invention will not make use of the addition of undesirable chemical substances, such as dyes and artificial pigments and others, and can be preferably flavored with aromas and added with natural plant-based extracts with recognized pharmacological activity and / or substances with functional activities.
  • the process it also has the optional addition of isolated elements, of mineral or vegetable source such as vitamins, minerals etc. In this way, a different formulation is obtained from the sweeteners present in the state of the art and on the market.
  • the third and last modality of this invention resides in the use of the sweetener in table products and in the industry in general, for example in derivative products such as cakes, sweets, dairy products, cosmetics, jellies, sweets, food supplements, drugs, nutraceuticals, cereal bars, among others.
  • the present invention is based on inverted sucrose syrup made to measure for the production of sweetener and additive of sweeteners and others.
  • the sweetener thus produced may have as a preferential origin dark VHP / VVHP / Demerara / Brown sugars rich in minerals, vitamins and natural antioxidants with great pharmacological appeal, offering the sweetness and natural flavor of sugar and added with sweeteners, be they natural or synthetic to increase sweetness, which leads to a decrease in the amount of sugar used to sweeten, but preserving sweetness and flavor while preserving the qualities of dark sugars.
  • the sweeteners proposed here use inverted sugar having equimolar parts of glucose and fructose, and for this reason the product gains sweetness with fewer calories, preferably through a totally natural process, via biological and GMO-free (technology which does not make use of genetically modified organisms) or by commercial enzymes and blends with sweeteners that enhance the sweetness of the product, reducing the amount used for the same sweetness, as well as the calories ingested.
  • the present invention therefore describes COMPOSITION, PROCESS OF PRODUCTION AND USE OF NUTRITIVE SWEETS AND BLENDS based on inverted sugar, reaching a composition that allows the consumer the full pleasure of the sugar flavor, but with a significant reduction of calories in the product , as an example, in blends with preferably natural sweeteners.
  • sweetener proposed here can be added with natural plant extracts such as ginger, cinnamon, lemon, pomegranate, acerola, passion fruit, but not limited to these only.
  • the sweeteners now have the intrinsic pharmacological functionality of each extract, in addition to giving the sweetener flavor notes of the extract in particular, thus enhancing the qualities of dark sugars in natural pharmacological activities which are preserved when enzyme inversion process is used.
  • VHP or demerara or brown sugar as a base for the manufacture of the sweetener, allows the product to have an important set of mineral salts, vitamins and antioxidants from sugar cane, as described in the following example:
  • Table 2 Concentration range obtained for the minerals analyzed by Inductively Coupled Plasma Atomic Emission Spectrometry (ICP OES) in different types of sugar [Silva, AFS. Characterization and determination of minerals in Brazilian sugar samples. Master's thesis. ESALQ, USP, Piracicaba, 2017].
  • ICP OES Inductively Coupled Plasma Atomic Emission Spectrometry
  • the sweetener of the present invention may contain pharmacological compounds, for example, those present in VHP, Demerara and Brown sugars, such as flavonoids and phenolic acids such as luteolin, apigenin, tricine, quercetin, kamferol , caffeic acid, apigenin, luteolin, tricin, chlorogenic acid, cumaric acid and ferulic acid.
  • pharmacological compounds for example, those present in VHP, Demerara and Brown sugars, such as flavonoids and phenolic acids such as luteolin, apigenin, tricine, quercetin, kamferol , caffeic acid, apigenin, luteolin, tricin, chlorogenic acid, cumaric acid and ferulic acid.
  • pharmacological compounds for example, those present in VHP, Demerara and Brown sugars, such as flavonoids and phenolic acids such as luteolin, apigenin, tricine, quercetin, kamferol
  • the present invention therefore presents a composition of a sweetener capable of maintaining the pharmacological properties of dark sugars that have been shown to assist in maintaining the muscle tone of the digestive tract wall; improve the health of the nervous system; strengthen skin, nails and hair; they improve the functioning of the liver, accelerate wound healing and prevent and treat anemia due to the presence of iron.
  • a sweetener capable of maintaining the pharmacological properties of dark sugars that have been shown to assist in maintaining the muscle tone of the digestive tract wall; improve the health of the nervous system; strengthen skin, nails and hair; they improve the functioning of the liver, accelerate wound healing and prevent and treat anemia due to the presence of iron.
  • the process of the present invention performs the inversion of sucrose by raising its sweetness from the level of 100 (crystal sucrose) to 120 (sucrose syrup with 98.0% inversion and with equimolar portions of glucose and fructose) , with a 20% gain in sweetness, considering the same amount of sucrose, since fructose has a sweetness index higher than sucrose and glucose.
  • the sucrose is almost completely converted to equimolar parts of glucose and fructose, without significantly losing its nutritional characteristics regarding vitamins, antioxidants and minerals present before its inversion.
  • the enzyme invertase preferably free of genetically modified organisms - GMO Free
  • non-GMO-free invertase enzyme unlike chemical inversion, does not form toxic compounds in the inversion process, such as, for example, furfural.
  • the optional addition of functional fibers may allow the sweetener of the present invention to have a glycemic index considered low ( ⁇ 55). What makes it more suitable for diets that seek to avoid diseases, such as diabetes and obesity problems.
  • Vitamins, minerals, amino acids and fibers can be added.
  • one of the ways of producing the sweetener begins with the dilution of the solid sucrose, present in the selected carbohydrate source with water to a sucrose syrup of 78.0 Q Brix and heated to 80 Q C for total dissolution of sucrose, with agitation in the tank. This syrup is then cooled to 55.0 to 60.0 Q C and the pH adjusted to 4.5 with the use of citric acid.
  • the invertase enzyme GMO-free or commercial, is added to the syrup and the reaction is maintained until the time necessary to achieve the desired inversion (greater than 90.0% and up to 98.0%) of the sucrose in glucose and fructose under the conditions described, obtaining a syrup with equimolar parts of glucose and fructose and a low concentration of sucrose, presenting a higher sweetness than that of non-inverted sucrose, which allows to use less quantity of product in relation to non-inverted sucrose to achieve the same sweetness.
  • the syrup can be added with natural or synthetic sweeteners, natural fibers, vitamins, minerals, amino acids, flavors, plant extracts, functional substances, other sugars, among others.
  • Fiber source The addition of fiber is an important aspect, as it allows the slower digestibility of carbohydrates, avoiding insulin spikes and improving the intestinal flora;
  • the present invention has found that the sweetener, with these and other advantages, can be obtained from small variations in the process described above with different types of sucrose and additives.
  • the following will be presented: illustrative examples of the processes and composition of the sweetener of the present invention, the values expressed in the Tables being based on [Ajibola A., Chamunorwa JP, Erlwanger KH. Nutraceutical values of natural honey and its contribution to human health and wealth. Nutrition & Metabolism 2012, 9:61; would do DAM. Nutritional and sensory study of organic and conventional crystal, refined, demerara and brown sugars. Master's thesis.
  • UFSCAR 2012; Luchini DL. Content of mineral nutrients and heavy metals in brown sugar produced by different organic and conventional systems. Master's thesis. UFSCAR, 2014; Moniruzzaman M, Chowdhury MAZ, Rahman MA, Sulaiman SA, Gan SH. Determination of mineral, trace element, and light pesticide in honey samples originating from different regions of Malaysia compared to Manuka Honey. Biomed. Int. Res. 2014, ID 359890; Nogueira FS, Ferreira KS, Carneiro J ⁇ nior JB, Passoni LC. Minerals in molasses and sugarcane juice. Food Science and Technology 2009, 29: 727-731; Silva AFS. Characterization and determination of minerals in Brazilian sugar samples. Master's thesis. ESALQ, USP, Piracicaba, 2017].
  • Example 1 Production of the sweetener from inverted cane sugar ENZYMATICALLY:
  • Solid sucrose is diluted with water to a sucrose syrup of 78.0 Q Brix and heated to 80 Q C for total dissolution of the sugar, with agitation in the tank;
  • the syrup is filtered to remove particulates
  • the filtered syrup can be added with sweeteners, for example EsEstevia, in the concentration that allows the final syrup to have twice the sweetness and half the calories, and this proportion can be changed to greater or lesser as required.
  • sweeteners for example EsEstevia
  • 1 kg of inverted sugar syrup is added with 2.6 g of EsEstevia, with EsEstevia being on average 300 x sweeter than sucrose, the product (1 kg) has a sweetness of 2 Kg of sucrose.
  • sucrose sugar to sweeten a traditional coffee
  • 2.5 g of the product would be used to sweeten the same coffee with the same sweetness of the 5 g of sucrose pure, but with half the calories.
  • other sweeteners can be used to add the syrup, according to its sweetening power (Table 3).
  • EXAMPLE 1 refers to:
  • CRYSTAL SUGAR may be organic, non-organic or refined as the basis of the sweetener of the present invention
  • Table 3 Comparative example of the sweetener and calories of the proposed sweetener in inverted crystal sucrose.
  • solid crystal sugar has an average of 387 Kcal per 100 g of product and sweetness reference once.
  • Example 2 Production of the sweetener from CHEMICALLY inverted cane sugar:
  • sucrose is diluted with water to a sucrose syrup of 78.0 Q Brix and heated to 80 Q C for total dissolution of the sugar, under intense agitation in the tank;
  • the pH of the syrup is corrected with a wedge at pH 4.5 to 5.0;
  • the syrup is filtered to remove particulates
  • the filtered syrup can be added with sweetener, for example Estevia, in a concentration that allows the final syrup to have twice the sweetness and half the calories, and this proportion can be changed to greater or lesser as needed.
  • sweetener for example Estevia
  • other sweeteners can be used to add the syrup, according to its sweetening power (Table 4).
  • EXAMPLE 2 refers to:
  • CRYSTAL SUGAR which may be organic, non-organic or refined
  • the base of the sweetener as shown in example 1, but without the use of an enzyme
  • Table 4 Comparative example of sweetness and calories of the proposed sweetener in crystal sucrose.
  • solid crystal sugar has an average of 387 Kcal per 100 g of product and sweetness reference once.
  • sucrose is diluted with water to a sucrose syrup of 78.0 Q Brix and heated to 80 Q C for total dissolution of the sugar, under intense agitation in the tank;
  • the syrup is filtered to remove particulates
  • the filtered syrup can be added with sweetener, for example Estevia, in a concentration that allows the final syrup to have twice the sweetness and half the calories, and this proportion can be changed to greater or lesser as needed.
  • sweetener for example Estevia
  • Example, 1 Kg of inverted sugar syrup is added with 2.6 g of Estevia, being that Estevia is on average 300 x sweeter than sucrose, the product (1Kg) has a sweetness of 2 Kg of sucrose.
  • other sweeteners can be used to add the syrup, according to its sweetening power (Table 5).
  • EXAMPLE 3 refers to:
  • Table 5 Comparative example of sweetness and calories of the proposed sweetener in inverted crystal sucrose.
  • crystal sugar it has an average of 387 Kcal per 100 g of product and a sweetness reference of 1 time.
  • Example 4 Production of the sweetener from VHP or VVHP sugar:
  • VVHP Very High Polarization sucrose or solid VHP (Very High Polarization) is diluted with water in a sucrose syrup of 78.0 Q Brix and heated to 80 Q C for total dissolution of the sugar, under agitation in the tank;
  • the syrup is inverted CHEMICALLY (organic products or not) or ENZYMATICALLY as described in the previous examples;
  • the syrup is filtered to remove particulates
  • the filtered syrup can be added with sweetener, for example Estevia, in a concentration that allows the final syrup to have twice the sweetness and half the calories, and this proportion can be changed to greater or lesser as needed.
  • sweetener for example Estevia
  • other sweeteners can be used to add the syrup, according to its sweetening power (Table 6).
  • EXAMPLE 4 refers to:
  • VHP or VVHP sugars organic or not
  • Table 6 Comparative example of the sweetener and calories of the proposed sweetener and sucrose VVHP or inverted VHP.
  • solid VHP sugar has an average of 380 Kcal per 100 g of product and sweetness reference once.
  • Solid Demerara sucrose is diluted with water to a sucrose syrup of 78.0 Q Brix and heated to 80 Q C for total dissolution of the sugar, with agitation in the tank;
  • the syrup is inverted CHEMICALLY (organic products or not) or ENZYMATICALLY as described in the previous examples;
  • the syrup is filtered to remove particulates
  • the filtered syrup can be added with sweetener, for example Estevia, in a concentration that allows the final syrup to have twice the sweetness and half the calories, and this proportion can be changed to greater or lesser as needed.
  • sweetener for example Estevia
  • 1 kg of inverted sugar syrup is added with 2.6 g of Estevia, with Estevia being on average 300 x sweeter than sucrose, the product has a sweetness of 2 kg of sucrose.
  • other sweeteners can be used to add the syrup, according to its sweetening power (Table 7).
  • EXAMPLE 5 refers to:
  • Table 7 Comparative example of the sweetener and calories of the proposed sweetener in inverted Demerara sucrose.
  • Demerara sugar has an average of 380 Kcal per 100 g of product and sweetness reference once.
  • Solid brown sugar is diluted with water to a sucrose syrup of 78.0 Q Brix and heated to 80 Q C for total dissolution of the sugar, with agitation in the tank;
  • the syrup is inverted CHEMICALLY (organic products or not) or ENZYMATICALLY as described in the previous examples;
  • the syrup is filtered to remove particulates
  • the filtered syrup can be added with sweetener, for example Estevia, in a concentration that allows the final syrup to have twice the sweetness and half the calories, and this proportion can be changed to greater or lesser as needed.
  • sweetener for example Estevia
  • 1 kg of inverted sugar syrup is added with 2.6 g of Estevia, with Estevia being on average 300 x sweeter than sucrose, the product has a sweetness of 2 kg of sucrose.
  • other sweeteners can be used to add the syrup, according to its sweetening power (Table 8).
  • EXAMPLE 6 refers to:
  • Table 8 Comparative example of the sweetener and calories of the proposed sweetener and brown sugar.
  • Demerara sugar has an average of 380 Kcal per 100 g of product and sweetness reference once.
  • Example 7 Sweetener production from sugar beet, coconut and others:
  • the syrup is inverted CHEMICALLY (organic products or not) or ENZYMATICALLY as described in the previous examples;
  • the syrup is filtered to remove particulates
  • the filtered syrup can be added with sweetener, for example Estevia, in a concentration that allows the final syrup to have twice the sweetness and half the calories, and this proportion can be changed to greater or lesser as needed.
  • sweetener for example Estevia
  • 1 kg of inverted sugar syrup is added with 2.6 g of Estevia, with Estevia being on average 300 x sweeter than sucrose, the product has a sweetness of 2 kg of sucrose.
  • other sweeteners can be used to add the syrup, according to its sweetening power (Table 9).
  • EXAMPLE 7 refers to:
  • Table 9 Comparative example of the sweetener and calories of the proposed sweetener and coconut sugar.
  • coconut sugar has an average of 380 Kcal per 100 g of product and sweetness reference once.
  • Example 8 Sweetener production from different sugars with added fibers:
  • Solid sucrose of any type of sugar is diluted with water in a syrup sucrose of 78.0 Q Brix and heated to 80 Q C for total dissolution of the sugar, with agitation in the tank;
  • the syrup is inverted CHEMICALLY (organic products or not) or ENZYMATICALLY as described in the previous examples;
  • the syrup is filtered to remove particulates
  • the filtered syrup can be added with sweetener according to examples 1 to 7.
  • the sweetener can be added with:
  • organic soluble fibers or not, such as, for example: corn fibers, polydextroses, soluble maltodextrins or cassava fibers;
  • organic or non-insoluble fibers such as, for example, corn or cassava or vegetable fibers
  • EXAMPLE 8 refers to:
  • Adequate consumption of fiber in the usual diet can reduce the risk of developing some chronic diseases such as: coronary artery disease [Liu
  • Dietary fiber is resistant to the action of human digestive enzymes and consists of polymers of carbohydrates, with three or more monomeric units plus lignin [Anderson JW, Baird P, Davis RH Jr, Ferreri S, Knudtson M, Koraym A , et al. Health benefits of dietary fiber. Nutr Rev 67 (4): 188-205, 2009; Howlett JF, Betteridge VA, Champ M, Craig SAS, Meheust A, Jones JM. The definition of dietary fiber - discussions at the Ninth Vahouny Fiber Symposium: building scientific agreement. Food Nutr Res 54: 5750, 2010].
  • dietary fiber The components of dietary fiber are divided into groups: non-starch polysaccharides, oligosaccharides, analogous carbohydrates (resistant starch and resistant maltodextrins), lignin, compounds associated with dietary fiber (phenolic compounds, cell wall protein, oxalates, phytates, waxes, cutin and suberin) and animal fibers (chitin, chitosan, collagen and chondroitin) [Tungland BC, Mayer D. Nondigestible oligo- and polysaccharides (dietary fiber): their physiology and role in human health and food. Comp Rev Food Sci Food Saf 1: 73-92, 2002].
  • sucrose of any type of sugar is diluted with water to a sucrose syrup of 78.0 Q Brix and heated to 80 Q C for total dissolution of the sugar, under intense agitation in the tank; 2.
  • the syrup is inverted CHEMICALLY (organic products or not) or ENZYMATICALLY as described in the previous examples;
  • the syrup is filtered to remove particulates
  • the filtered syrup can be added with sweeteners according to examples 1 to 7;
  • the syrup can be added with fibers
  • the syrup can be added with different types of amino acids such as: glutamic acid, aspartic acid, glutamine, histidine, glycine, threonine, alanine, arginine, proline, tyrosine, valine, methionine, cysteine, leucine, phenylalanine, isoleucine, tryptophan, ornithine and lysine, among others, ensuring that in the final product, the various amino acids of interest can be present.
  • the daily recommendation for branched-chain amino acids for adults according to the FAO / WHO (2011) is 20 mg / kg of isoleucine, 26 mg / kg of valine and 39 mg / kg of leucine. Therefore, for each amino acid, it is necessary to evaluate the recommended RDI (Reference Dietary Intake).
  • Example 10 Production of the sweetener from sugars of the different sugars with added fibers, amino acids and mineral additives:
  • Solid sucrose of any type of sugar is diluted with water to a sucrose syrup of 78.0 Q Brix and heated to 80 Q C for total dissolution of the sugar, with agitation in the tank;
  • the syrup is inverted CHEMICALLY (organic products or not) or ENZYMATICALLY as described in the previous examples;
  • the syrup is filtered to remove particulates
  • the filtered syrup can be added with sweeteners as examples
  • the sweetener can be added with fibers, according to Example 8.
  • the sweetener can be added with amino acids according to Example 9;
  • the sweetener can be added using the daily intake dose of Zinc, Calcium, Phosphorus, Iron and Magnesium minerals as a reference to the range indicated for the different age groups or needs according to ANVISA Regulation approved by Decree n Q 3,029, of April 16, 1999, with art. 111, item I, item “e” of the Internal Regulations approved by Ordinance No. Q 593, of August 25, 2000, published in the DOU of December 22, 2000, in a meeting held on December 6, 2004. Other national regulations or international agreements can also be used as a Also other minerals, such as copper, selenium, manganese and phosphorus, can be added within the limits according to the references of the various regulations.
  • EXAMPLE 10 refers to:
  • the sweetener can present the composition as an example of Table 10.
  • Table 10 Example of composition of the proposed sweetener with the additives and using inverted Demerara sugar (98% inversion) as base syrup.
  • Example 11 Production of the sweetener from sugars of different sugars with the addition of fibers, amino acids, with minerals and vitamins:
  • Solid sucrose of any type of sugar is diluted with water to a sucrose syrup of 78.0 Q Brix and heated to 80 Q C for total dissolution of the sugar, with agitation in the tank;
  • the syrup is inverted CHEMICALLY (organic products or not) or ENZYMATICALLY as described in the previous examples;
  • the syrup is filtered to remove particulates; 4.
  • the filtered syrup can be added with sweeteners as examples
  • the sweetener can be added with fibers, according to Example 8.
  • the sweetener can be added with amino acids according to Example 9;
  • the sweetener can be added with minerals according to example 10.;
  • the syrup can be added by taking as a reference the dose of daily intake of vitamins A, B, C, D and E, folic acid, riboflavin, thiamine and niacin as indicated for different age groups or groups of people. grace period according to ANVISA Regulation approved by Decree No. Q 3,029, of April 16, 1999, with art. 111, item I, item “e” of the Internal Regulations approved by Ordinance No. Q 593, of August 25, 2000, published in the DOU of December 22, 2000, in a meeting held on December 6, 2004. Other national regulations or international agreements can also be used as a Other vitamins, such as vitamin B5 - pantothenic acid and vitamin K, can be added according to the references of the various regulations.
  • EXAMPLE 11 refers to:
  • the sweetener can present the composition according to the example in Table 11.
  • Table 11 Example of the composition of the proposed sweetener with the additives and using inverted Demerara sugar (98% inversion) as base syrup. Example with 100% of the dose recommended by Anvisa.
  • Example 12 Production of the sweetener from sugars of the various sugars with the addition of fibers, amino acids, with added minerals and vitamins and encapsulated substances:
  • Solid sucrose of any type of sugar is diluted with water to a sucrose syrup of 78.0 Q Brix and heated to 80 Q C for total dissolution of the sugar, under intense agitation in the tank;
  • the syrup is inverted CHEMICALLY (organic products or not) or ENZYMATICALLY as described in the previous examples;
  • the syrup is filtered to remove particulates
  • the filtered syrup can be added with sweeteners as examples
  • the sweetener can be added with fibers, according to Example 8.
  • the sweetener can be added with amino acids according to Example 9;
  • the sweetener can be added with minerals according to Example 10;
  • the sweetener can be added with vitamins according to Example 11;
  • the sweetener can be added with encapsulated, micro encapsulated or nano-encapsulated substances, for example, cane molasses, cane honey, pharmacological and nutraceutical compounds, natural plant extracts, but not limited to these.
  • the encapsulation process preserves the pharmacological properties of the products and masks their possible interference in the organoleptic properties of the sweetener, however, it keeps its functional properties intact.
  • the proportion of additives will depend on the type of product to be added and the concentration of the substances of interest, being between 1.0 and 10.0% of the sweetener. Some of the additives like vitamins, amino acids and minerals can also be encapsulated.
  • Example 13 Production of the sweetener from sugars of the various sugars with the addition of fibers, amino acids, additives with minerals, vitamins, encapsulated substances and natural plant extracts:
  • Solid sucrose of any type of sugar is diluted with water to a sucrose syrup of 78.0 Q Brix and heated to 80 Q C for total dissolution of the sugar, under intense agitation in the tank;
  • the syrup is inverted CHEMICALLY (organic products or not) or ENZYMATICALLY as described in the previous examples;
  • the syrup is filtered to remove particulates
  • the filtered syrup can be added with sweeteners according to examples 1 to 7.
  • the sweetener can be added with fibers, according to Example 8.
  • the sweetener can be added with amino acids according to Example 9;
  • the sweetener can be added with minerals according to Example 10;
  • the sweetener can be added with vitamins according to Example 11;
  • the sweetener can be added with encapsulated substances according to Example 12;
  • the sweetener can be added with plant extracts with recognized pharmacological activities, such as ginger, pomegranate, lemon balm, cloves, cinnamon, mint, fennel, among several others that can be used to provide a functional activity to the sweetener. that the proportion of additives can be from 0.5% to 10.0% by weight of the sweetener, and the concentration may vary according to the application, commercial need or concentration of the active ingredient of the plant in the extract, not being limited only to these.
  • - Can be added with natural or synthetic sweetener; - It can be enriched with FIBERS;
  • PLANT EXTRACTS PLANT EXTRACTS
  • Example 14 Production of the sweetener from sugars of different sugars with the addition of fibers, amino acids, with mineral additives, vitamins, encapsulated substances, natural plant extracts and aromas:
  • Solid sucrose of any type of sugar is diluted with water to a sucrose syrup of 78.0 Q Brix and heated to 80 Q C for total dissolution of the sugar, under intense agitation in the tank;
  • the syrup is inverted CHEMICALLY (organic products or not) or ENZYMATICALLY as described in the previous examples;
  • the syrup is filtered to remove particulates
  • the filtered syrup can be added with sweeteners as examples
  • the sweetener can be added with fibers, according to Example 8.
  • the sweetener can be added with amino acids according to Example 9;
  • the sweetener can be added with minerals according to Example 10;
  • the sweetener can be added with vitamins according to Example 11;
  • the sweetener can be added with encapsulated substances according to Example 12;
  • the sweetener can be added with plant extracts according to Example 13:
  • the sweetener can be added with natural flavors, artificial flavors and flavors identical to natural ones, such as honey, lemon, passion fruit, orange, strawberry, ginger, cinnamon, tangerine, among several possibilities, with the proportion of additives can be from 0.5% to 5.0% by weight of the sweetener, and the concentration may vary depending on the application or commercial need. limiting only to these.
  • Example 15 Production of the sweetener from sugars of various sugars with the addition of fibers, amino acids, additives with minerals, vitamins, encapsulated substances, natural plant extracts, flavors and functional substances:
  • Solid sucrose of any type of sugar is diluted with water to a sucrose syrup of 78.0 Q Brix and heated to 80 Q C for total dissolution of the sugar, under intense agitation in the tank;
  • the syrup is inverted CHEMICALLY (organic products or not) or ENZYMATICALLY as described in the previous examples;
  • the syrup is filtered to remove particulates
  • the filtered syrup can be added with sweeteners according to examples 1 to 7;
  • the sweetener can be added with fibers, according to Example 8.
  • the sweetener can be added with amino acids according to Example 9;
  • the sweetener can be added with minerals according to Example 10;
  • the sweetener can be added with vitamins as per Example 11;
  • the sweetener can be added with encapsulated substances according to Example 12:
  • the sweetener can be added with plant extracts according to Example 13;
  • the sweetener can be added with flavors according to Example 14;
  • the sweetener can be added with functional substances, such as prebiotics such as: inulin, FOS (fructooligosaccharides), GOS (galactooligosaccharides), and antioxidants such as cane flavonoids, beta carotenes, carotenoids, lycopene, anthocyanins, resveratrol, tannins, among others , but not only limited to these.
  • prebiotics such as: inulin, FOS (fructooligosaccharides), GOS (galactooligosaccharides), and antioxidants such as cane flavonoids, beta carotenes, carotenoids, lycopene, anthocyanins, resveratrol, tannins, among others , but not only limited to these.
  • the proportion of additives will depend on the type of product to be added and the concentration of the substances of interest, being between 1.0 and 5.0% of the sweetener, but adjusting to the functional potential of the substance, as well as to the limits
  • Example 16 Production of the sweetener from sugars of different sugars with the addition of fibers, amino acids, with mineral additives, vitamins, encapsulated substances, natural plant extracts, flavorings, functional substances and other sugars:
  • Solid sucrose of any type of sugar is diluted with water to a sucrose syrup of 78.0 Q Brix and heated to 80 Q C for total dissolution of the sugar, under intense agitation in the tank;
  • the syrup is inverted CHEMICALLY (organic products or not) or ENZYMATICALLY as described in the previous examples;
  • the syrup is filtered to remove particulates
  • the filtered syrup can be added with sweeteners according to examples 1 to 7;
  • the sweetener can be added with fibers, according to Example 8.
  • the sweetener can be added with amino acids according to Example 9;
  • the sweetener can be added with minerals according to Example 10;
  • the sweetener can be added with vitamins according to Example 11;
  • the sweetener can be added with encapsulated substances according to Example 12;
  • the sweetener can be added with plant extracts according to Example 13:
  • the sweetener can be added with flavors according to Example 14;
  • the sweetener can be added with functional substances according to Example 15:
  • the sweetener can be added with other sugars such as examples: xylitol, high fructose syrups, erythritol, dextrose, maltose, sorbitol, mannitol, lactose, fruit syrups (example apple syrup), among others, but not only restricted to Those.
  • the proportion of additives can be between 0.1 to 50.0% of the sweetener, according to the ideal proportion and consumption limits according to the current legislation established by national or international regulatory bodies for each type of sugar.
  • the scope of the present invention also encompasses the different uses and applications of a sweetener composition with improved properties, as described in this invention.
  • the main applications are: Pharmaceutical Industry, Cosmetic Industry, Food Industry and Table use in general.

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Abstract

The present invention relates to the use, production method and composition of natural sweeteners and blends with natural or synthetic sweetening agents, based on inverted liquid sugars (VHP/VVHP/demerara/muscovado brown sugars rich in minerals, vitamins and natural antioxidants of great nutritional and pharmacological interest). The sugars are chemically or enzymatically inverted, containing the optional addition of nutritive and functional components constantly aiming for the healthfulness and functionality of the product, a formulation being obtained that preserves the flavour and characteristics of the sugar, but with reduced calories, coming from the inverted sucrose. The sweetener can be used as a table product and in the industry in general, for example in derivative products such as cakes, sweets, dairy products, cosmetics, jellies, sweets, food supplements, drugs, nutraceuticals and cereal bars, inter alia.

Description

COMPOSIÇÃO, PROCESSO DE PRODUÇÃO E USO DE ADOÇANTES NUTRITIVOS E BLENDAS COMPOSITION, PRODUCTION PROCESS AND USE OF NUTRITIVE SWEETENERS AND BLENDS
[001] A presente invenção refere-se à produção de adoçantes naturais e blendas à base de açúcares líquidos invertidos por via enzimática ou química, contendo adição opcional de componentes nutritivos e funcionais buscando sempre a saudabilidade e funcionalidade do produto. [001] The present invention relates to the production of natural sweeteners and blends based on inverted liquid sugars by enzymatic or chemical route, containing optional addition of nutritious and functional components always seeking the healthiness and functionality of the product.
[002] O adoçante da presente invenção se refere a um produto de origem vegetal, sendo produzido a base de sacarose invertida, preferencialmente por meio de catálise enzimática, pela mesma enzima utilizada pelas abelhas na produção do mel, de açúcares escuros VHP ou VVHP ou Demerara ou Mascavo ricos em minerais, vitaminas e antioxidantes naturais com grande apelo nutricional e farmacológico e também blendas do açúcar invertido com adoçantes naturais, como a Estevia, e opcionalmente com edulcorantes, buscando sempre exaltar o dulçor mantendo o sabor e características do açúcar no produto com o mínimo de calorias possível. Não possui adição ou produção de substâncias químicas maléficas a saúde humana (ex: furfural), adição de amido, todavia pode ser enriquecido com fibras, complemento de vitaminas, minerais, aminoácidos e produtos funcionais como extratos de plantas com potencial medicinal e substâncias funcionais, entre outros. O adoçante da presente invenção pode ser consumido diretamente ou na produção de outros produtos alimentícios, farmacêuticos, nutracêuticos ou cosméticos, não se limitando somente a estes. O adoçante também traz características de sabor de açúcar, shelf life, caramelização, sólidos, depression freezing point e textura muito próxima ao da sacarose, o que permite uma ampla possibilidade de substituição do uso da sacarose, glicose ou frutose mantendo-se as características do produto com ganho na redução da quantidade de calorias sendo uma alternativa importante que no que se refere a calorias ficando em termos de redução das mesmas entre os edulcorantes naturais/artificiais e açúcares de um modo geral. Uma nova opção de dulçor com sabor natural, orgânica ou não, ainda não disponível no mercado ANTECEDENTES DA INVENÇÃO [003] O ser humano sempre adicionou adoçantes em sua alimentação. O primeiro adoçante a ser utilizado foi o mel, o que pode ser comprovado por relatos nas culturas milenares como a chinesa e a grega. A seiva de árvores foi também muito utilizada, sendo a seiva do bordo do Canadá um exemplo, utilizada até os dias atuais. O mel foi posteriormente substituído pela sacarose originalmente obtida da cana-de-açúcar. A preferência por sabor adocicado é inata no ser humano. Isso pode já ser observado em recém-nascidos, que se acalmam com gotas de soro glicosado. [002] The sweetener of the present invention refers to a product of plant origin, being produced based on inverted sucrose, preferably by means of enzymatic catalysis, by the same enzyme used by bees in the production of honey, dark VHP or VVHP sugars or Demerara or Mascavo rich in minerals, vitamins and natural antioxidants with great nutritional and pharmacological appeal and also blends of inverted sugar with natural sweeteners, such as Estevia, and optionally with sweeteners, always seeking to exalt the sweetness maintaining the flavor and characteristics of the sugar in the product with as few calories as possible. There is no addition or production of harmful chemicals to human health (eg furfural), addition of starch, however it can be enriched with fibers, complement of vitamins, minerals, amino acids and functional products such as plant extracts with medicinal potential and functional substances, between others. The sweetener of the present invention can be consumed directly or in the production of other food, pharmaceutical, nutraceutical or cosmetic products, not being limited only to these. The sweetener also has characteristics of sugar flavor, shelf life, caramelization, solids, depression freezing point and texture very close to that of sucrose, which allows a wide possibility of substituting the use of sucrose, glucose or fructose while maintaining the characteristics of the product with gain in the reduction of the amount of calories being an important alternative that with regard to calories remaining in terms of reduction of the same among the natural / artificial sweeteners and sugars in general. A new sweetness option with natural flavor, organic or not, not yet available on the market BACKGROUND OF THE INVENTION [003] Human beings have always added sweeteners to their diet. The first sweetener to be used was honey, which can be confirmed by reports in ancient cultures such as Chinese and Greek. Tree sap was also widely used, Canada's maple sap being an example, used to this day. Honey was later replaced by sucrose originally obtained from sugar cane. The preference for sweet taste is innate in humans. This can already be seen in newborns, who calm down with drops of glycated serum.
[004] A humanidade conhece o sabor doce há mais de 5.000 anos e se tem registros de que em 510 AC o imperador Dario da Pérsia, invadiu a índia e descobriu uma palheta que “dá mel sem abelhas”. Essa palheta conhecida hoje como a cana-de- açúcar ( Saccharum officinarum) é uma das fontes de extração do açúcar, a qual é nativa das ilhas do Pacífico, mas a migração propagou-a por além-mar. Marco Pólo em suas viagens ao redor do mundo conheceu o açúcar e o levou para a Europa, passando a ser mais um item de luxo [Bye P, Meunier A, Muchnik J. As inovações açucareiras: permanência e diversidade de paradigmas Cadernos de Ciência & Tecnologia, Brasília, v.10, n.1/3, p.35-52, 1993]. [004] Humanity has known the sweet taste for more than 5,000 years and it is recorded that in 510 BC the emperor Darius of Persia invaded India and discovered a straw that “gives honey without bees”. This reed known today as sugar cane (Saccharum officinarum) is one of the sources of sugar extraction, which is native to the Pacific islands, but the migration has spread it overseas. Marco Pólo, on his travels around the world, discovered sugar and took it to Europe, becoming another luxury item [Bye P, Meunier A, Muchnik J. Sugar innovations: permanence and diversity of paradigms Cadernos de Ciência & Tecnologia, Brasília, v.10, n.1 / 3, p.35-52, 1993].
[005] Os séculos posteriores viram uma expansão e o açúcar passou a fazer parte integrante de nossa dieta e de nossa cultura. A evolução do açúcar modificou-se através do tempo, passando de moeda de troca internacional, a produto farmacêutico, fonte de calorias e substância usada na fabricação de outras fontes energéticas ou alimentares. Até uns 30 anos atrás o açúcar reinava absoluto tanto no uso doméstico como também na indústria, sendo considerado como ingrediente principal para adoçar [Bye P, Meunier A, Muchnik J. As inovações açucareiras: permanência e diversidade de paradigmas. Cadernos 42 de Ciência & Tecnologia, Brasília, v.10, n.1/3, p.35-52, 1993]. [005] Later centuries saw an expansion and sugar became an integral part of our diet and our culture. The evolution of sugar has changed over time, from an international currency of exchange, to a pharmaceutical product, a source of calories and a substance used in the manufacture of other energy or food sources. Until about 30 years ago, sugar reigned absolute both in domestic use and in industry, being considered as the main ingredient for sweetening [Bye P, Meunier A, Muchnik J. Sugar innovations: permanence and diversity of paradigms. Cadernos 42 de Ciência & Tecnologia, Brasília, v.10, n.1 / 3, p.35-52, 1993].
[006] A transição nutricional ocorrida neste século trouxe mudanças nos padrões nutricionais resultantes de modificações na estrutura da dieta dos indivíduos, resultando na chamada “dieta ocidental” caracterizada pelo alto consumo de gordura, açúcar e alimentos refinados. [006] The nutritional transition that occurred in this century brought changes in nutritional patterns resulting from changes in the structure of the individuals' diet, resulting in the so-called “western diet” characterized by high consumption of fat, sugar and refined foods.
[007] Os adoçantes são produtos especificamente desenvolvidos para dar sabor doce aos alimentos e bebidas, tendo a sacarose (açúcar de cana ou de beterraba) como principal exemplo. Nos produtos industrializados, o açúcar é largamente utilizado por seu efeito conservante, antioxidante e antimicrobiano e substituído algumas vezes pelos adoçantes edulcorantes [BRASIL. ANVISA Agência Nacional da Vigilância Sanitária. Resolução - RDC n°3 de 2 janeiro de 2001 Adoçantes: Limitações e Aprovações pela ANVISA. Disponível em: http://pt.shvoong.com/medicine- and- health/nutrition/1787176-anvisadecide-limitar-uso-dois/ Acesso em: 05 abril 2019]. [007] Sweeteners are products specifically developed to give a sweet taste to food and beverages, with sucrose (cane or beet sugar) as the main example. In industrialized products, sugar is widely used for its preservative, antioxidant and antimicrobial effect and is sometimes replaced by sweetening sweeteners [BRAZIL. ANVISA National Health Surveillance Agency. Resolution - RDC n ° 3 of January 2, 2001 Sweeteners: Limitations and Approvals by ANVISA. Available at: http://en.shvoong.com/medicine- and- health / nutrition / 1787176-anvisadecide-limit-usage-two / Accessed: 05 April 2019].
[008] Por outro lado, os edulcorantes são substâncias químicas responsáveis pelo sabor doce e normalmente possuem um poder adoçante muito superior à sacarose, sendo necessária, portanto, uma quantidade muito menor para se obter a mesma doçura, com a vantagem de ter menos ou nenhuma caloria. Por exemplo, os adoçantes dietéticos são constituídos basicamente por edulcorantes e agentes de corpo, também chamados de veículos e são compostos utilizados com a finalidade de diluir os edulcorantes dando volume ao produto [Cesar P. Portal de Estudos em Química: A química na cozinha apresenta: O açúcar. Disponível em: http://www.profpc.com.br/Qu%C3%ADmica%20na%20Cozinha/A%C3%A7%C 3%BAcar/ado%C3%A7ante_artificial.htm. Acesso em: 05 abr. 2019]. [008] On the other hand, sweeteners are chemical substances responsible for the sweet taste and usually have a sweetening power far superior to sucrose, therefore requiring a much smaller amount to obtain the same sweetness, with the advantage of having less or less sweetness. no calories. For example, dietary sweeteners are basically made up of sweeteners and body agents, also called vehicles and are compounds used with the purpose of diluting sweeteners by adding volume to the product [Cesar P. Chemistry Study Portal: Chemistry in the kitchen presents : The sugar. Available at: http://www.profpc.com.br/Qu%C3%ADmica%20na%20Cozinha/A%C3%A7%C 3% BAcar / ado% C3% A7ante_artificial.htm. Accessed on: 05 abr. 2019].
[009] Os adoçantes podem ser classificados em nutritivos e não-nutritivos. Os adoçantes nutritivos incluem os açúcares calóricos como: a sacarose, a frutose, a dextrose, a lactose, a maltose, o mel, o xarope de milho, o xarope de milho rico em frutose, o melado, os açúcares invertidos, os sucos de frutas concentrados e os polióis, também chamados de açúcares de álcool, tais como sorbitol, manitol, xilitol e outros (chamados de hidrolisados de amido hidrogenados) [ADA Reports. Position of the American Dietetic Association: use of nutritive and nonnutritive sweeteners. J Am Diet Assoe; 104(2):255-75, 2004. Erratum in: J Am Diet Assoe. 104(6): 1013, 2004]. [009] Sweeteners can be classified into nutritious and non-nutritive. Nutritional sweeteners include caloric sugars such as sucrose, fructose, dextrose, lactose, maltose, honey, corn syrup, high fructose corn syrup, molasses, inverted sugars, fruit juices concentrated fruits and polyols, also called alcohol sugars, such as sorbitol, mannitol, xylitol and others (called hydrogenated starch hydrolysates) [ADA Reports. Position of the American Dietetic Association: use of nutritive and nonnutritive sweeteners. J Am Diet Assoe; 104 (2): 255-75, 2004. Erratum in: J Am Diet Assoe. 104 (6): 1013, 2004].
[010] Os adoçantes não-nutritivos passaram a ser utilizados durante o período entre as guerras em decorrência da escassez do açúcar. A partir de 1950 ocorreu uma mudança no motivo da utilização: passou da preocupação com custo para a redução de ingestão de calorias. São considerados aditivos alimentares. Apesar da intensa utilização dessas substâncias na atualidade, nas diferentes faixas etárias e em todas as camadas sociais, ainda existe muita dúvida em relação aos possíveis efeitos colaterais associados ao seu uso. [010] Non-nutritive sweeteners started to be used during the inter-war period due to the scarcity of sugar. From 1950 on, there was a change in the reason for use: it went from being concerned with cost to reducing calorie intake. They are considered food additives. Despite the intense use of these substances today, in different age groups and in all social strata, there is still a lot of doubt regarding the possible side effects associated with their use.
[011] Muitas vezes, as pessoas ingerem adoçantes sem terem consciência disso. Isto porque vários alimentos industrializados, como balas, doces, chicletes, sucos, refrigerantes, cremes dentais e medicamentos contêm adoçantes. [011] Often, people ingest sweeteners without being aware of it. This is because various industrialized foods, such as candies, sweets, chewing gum, juices, soft drinks, toothpastes and medicines contain sweeteners.
[012] O consumo diário aceitável dos adoçantes, mesmo os naturais, é definido pela OMS (Organização Mundial de Saúde) e é chamado de IDA (Ingestão Diária Aceitável) e está relacionada ao peso do indivíduo. As recomendações para uma dieta equilibrada são 50% do seu teor energético na forma de carboidratos e, destes, somente 10% a 15% devem ser provenientes da ingestão de açúcares [Glinsmann WH, Frausquin H, ParkYK. Evaluation of health aspects of sugar contained in carbohydrate sweeteners. Report of SugarsTask Force. J Nutr 116:5-119, 1986; Rossoni E, Graebin LB, Moura RP. Adoçantes presentes na formulação de refrigerantes, sucos e chás diet e light. Rev Fac Odontol Port Alegre, 48:5-11, 2007]. [012] Acceptable daily consumption of sweeteners, even natural ones, is defined by WHO (World Health Organization) and is called IDA (Acceptable Daily Intake) and is related to the individual's weight. Recommendations for a balanced diet are 50% of their energy content in the form of carbohydrates and, of these, only 10% to 15% should come from sugar intake [Glinsmann WH, Frausquin H, ParkYK. Evaluation of health aspects of sugar contained in carbohydrate sweeteners. Report of SugarsTask Force. J Nutr 116: 5-119, 1986; Rossoni E, Graebin LB, Moura RP. Sweeteners present in the formulation of soft drinks, juices and teas diet and light. Rev Fac Odontol Port Alegre, 48: 5-11, 2007].
Principais adoçantes nutritivos Main nutritional sweeteners
[013] A sacarose é um dissacarídeo composto por glicose e frutose e foi o principal adoçante usado na primeira metade do século passado. A ingestão varia de 14 a 60 g/dia, com média de 41 g/dia, consistindo em cerca de 7% a 11% das calorias ingeridas, nos EUA. Fornece 4Kcal/g. [ADA Reports. Position of the American Dietetic Association: use of nutritive and non-nutritive sweeteners. J Am Diet Assoe 104 (2):255- 75, 2004. Erratum in: J Am Diet Assoe 104(6):1013, 2004]. [013] Sucrose is a disaccharide composed of glucose and fructose and was the main sweetener used in the first half of the last century. Intake ranges from 14 to 60 g / day, averaging 41 g / day, consisting of about 7% to 11% of calories ingested in the USA. Provides 4Kcal / g. [ADA Reports. Position of the American Dietetic Association: use of nutritive and non-nutritive sweeteners. J Am Diet Assoe 104 (2): 255-75, 2004. Erratum in: J Am Diet Assoe 104 (6): 1013, 2004].
[014] A frutose é um monossacarídeo encontrado principalmente nas frutas. É encontrado como componente dos xaropes de milho ricos em frutose. A frutose cristalina é obtida a partir do amido de milho através da isomerização. Fornece 4 Kcal/g. A frutose tem sido associada em vários estudos epidemiológicos como aumento de peso, triglicérides, pressão arterial elevada e resistência à insulina e aumento nos níveis de ácido úrico. Tem poder adoçante 1 ,7 vezes em relação à sacarose. Tem vantagens em relação à glicose e à sacarose, pois, além de mais doce, tem mais solubilidade que a glicose e a sacarose. Seu metabolismo não depende da insulina. A dose diária aceitável é de até 50g/dia [Livesey G, Taylor R. Fructose consumption and consequences for glycation, plasma triacylglycerol, and body weight: meta analyses and meta- regression models of intervention studies. Am J Clin utr 88(5): 1419- 37, 2008]. [014] Fructose is a monosaccharide found mainly in fruits. It is found as a component of high fructose corn syrups. Crystalline fructose is obtained from corn starch through isomerization. Provides 4 Kcal / g. Fructose has been associated in several epidemiological studies such as weight gain, triglycerides, high blood pressure and insulin resistance and increase in uric acid levels. It has sweetening power 1, 7 times in relation to sucrose. It has advantages in relation to glucose and sucrose, because, in addition to being sweeter, it has more solubility than glucose and sucrose. Your metabolism does not depend on insulin. The acceptable daily dose is up to 50g / day [Livesey G, Taylor R. Fructose consumption and consequences for glycation, plasma triacylglycerol, and body weight: meta analyzes and meta-regression models of intervention studies. Am J Clin utr 88 (5): 1419-37, 2008].
[015] A glicose, que é também um monossacarídeo, é encontrada em frutas, verduras e mel. Absorvida no intestino delgado. Não provoca fermentação intestinal. Tem menor efeito adoçante que a sacarose. Fornece 4Kcal/g [Tumas R, Goastico SSV, Gandolfo AS. Adoçantes. In: Delgado AF, Cardoso AL, Zamberlan P. Adoçantes in nutrologia básica e avançada. São Paulo: Manole; 2010]. [015] Glucose, which is also a monosaccharide, is found in fruits, vegetables and honey. Absorbed in the small intestine. It does not cause intestinal fermentation. It has less sweetening effect than sucrose. Provides 4Kcal / g [Tumas R, Goastico SSV, Gandolfo AS. Sweeteners. In: Delgado AF, Cardoso AL, Zamberlan P. Sweeteners in basic and advanced nutrology. São Paulo: Manole; 2010].
[016] A lactose é o açúcar do leite e é um dissacarídeo composto por uma molécula de glicose e uma de galactose. Tem poder adoçante inferior ao da sacarose. Pode levar à fermentação intestinal nos indivíduos com deficiência da lactase. Fornece 4 Kcal/g [Tumas R, Goastico SSV, Gandolfo AS. Adoçantes. In: Delgado AF, Cardoso AL, Zamberlan P. Adoçantes in nutrologia básica e avançada. São Paulo: Manole; 2010]. [016] Lactose is milk sugar and is a disaccharide composed of one molecule of glucose and one of galactose. It has a lower sweetening power than sucrose. It can lead to intestinal fermentation in individuals with lactase deficiency. Provides 4 Kcal / g [Tumas R, Goastico SSV, Gandolfo AS. Sweeteners. In: Delgado AF, Cardoso AL, Zamberlan P. Sweeteners in basic and advanced nutrology. São Paulo: Manole; 2010].
[017] Polióis ou álcoois de açúcar, como sorbitol, manitol e xilitol têm a metade do sabor adocicado da sacarose. São menos calóricos que a sacarose, a glicose e a frutose e fornecem entre 1 ,6 e 2,6 Kcal/g. O sorbitol ainda tem a vantagem de estimular a motilidade da vesícula biliar. A Organização Mundial de Saúde, através do Comité de Avaliação de Adoçantes, concluiu que a quantidade aceitável de ingestão diária de sorbitol não está especificada, isto é, não existem limites específicos. Porém, como os polióis têm absorção intestinal incompleta podem levar a quadros diarreicos [ADA Reports. Position of the American Dietetic Association: use of nutritive and non-nutritive sweeteners. J Am Diet Assoe 2004, 104 (2):255-75. Erratum in: J Am Diet Assoe 104(6):1013, 2004; Joint FAO/WHO Expert Committee on Food Additives. Toxicological evaluation of certain food additives: sorbitol. Twenty-sixth report. Geneva: WHO; 1982. p. 218-28. WHO Technical Report Series, 683]. [017] Polyols or sugar alcohols such as sorbitol, mannitol and xylitol have half the sweet taste of sucrose. They are less caloric than sucrose, glucose and fructose and provide between 1, 6 and 2.6 Kcal / g. Sorbitol also has the advantage of stimulating gallbladder motility. The World Health Organization, through the Committee for the Evaluation of Sweeteners, concluded that the acceptable amount of daily intake of sorbitol is not specified, that is, there are no specific limits. However, as polyols have incomplete intestinal absorption, they can lead to diarrheal conditions [ADA Reports. Position of the American Dietetic Association: use of nutritive and non-nutritive sweeteners. J Am Diet Assoe 2004, 104 (2): 255-75. Erratum in: J Am Diet Assoe 104 (6): 1013, 2004; Joint FAO / WHO Expert Committee on Food Additives. Toxicological evaluation of certain food additives: sorbitol. Twenty-sixth report. Geneva: WHO; 1982. p. 218-28. WHO Technical Report Series, 683].
Adoçantes não-nutritivos Non-nutritive sweeteners
[018] Os adoçantes não-nutritivos são também chamados de adoçantes intensos, de baixa caloria ou adoçantes alternativos. Atualmente, nos EUA, cinco adoçantes não- nutritivos (sacarina, , ciclamato, aspartame, acesulfame, sucralose e alitame) são aprovados pelo FDA, um açúcar não-calórico, derivado de uma planta (rebaudiosidio A, Estevia) e a proteína Taumatina, são reconhecidos como seguro pelo FDA [Pepino MY, Bourne C. Non-nutritive sweeteners, energy balance, and glucose homeostasis. Curr Opin Clin Nutr Metab Care 14:391-5, 2011 ; Kroger M, Meister K, Kava R. Low-calorie Sweeteners and Other Sugar Substitutes: A Review of the Safety Issues. Comprehensive Reviews in Food Science and Food Safety 5: 35-47, 2006]. [018] Non-nutritive sweeteners are also called intense, low-calorie sweeteners or alternative sweeteners. Currently, in the USA, five non-nutritive sweeteners (saccharin, cyclamate, aspartame, acesulfame, sucralose and alitame) are approved by the FDA, a non-caloric sugar derived from a plant (rebaudiosidio A, Estevia) and the protein Taumatina, are recognized as safe by the FDA [Pepino MY, Bourne C. Non-nutritive sweeteners, energy balance, and glucose homeostasis. Curr Opin Clin Nutr Metab Care 14: 391-5, 2011; Kroger M, Meister K, Kava R. Low-calorie Sweeteners and Other Sugar Substitutes: A Review of the Safety Issues. Comprehensive Reviews in Food Science and Food Safety 5: 35-47, 2006].
[019] A sacarina é o mais antigo e é proveniente do metilantranilato, substância que aparece naturalmente nas uvas. Foi descoberta em 1875 por Constantin Fahlberg, da Universidade John Flopkins, enquanto estudava a oxidação das sulfonamidas (o- toluenosulfanamida), substâncias obtidas de derivados do petróleo [Kroger M, Meister K, Kava R. Low-calorie Sweeteners and Other Sugar Substitutes: A Review of the Safety Issues. Comprehensive Reviews in Food Science and Food Safety 5:35-47, 2006]. É cerca de 300 vezes mais doce que a sacarose, estável ao calor e não-cardiogênico. Tem meia vida longa, porém apresenta um gosto residual metálico/amargo. Não é metabolizado no sistema digestivo humano, é excretado rapidamente pela urina e não se acumula no organismo humano. A ingestão diária aceitável é de 3,5 mg/Kg. Estudos mostrando fraca associação entre consumo de altas doses e câncer em ratos fizeram com que, em 1977, o FDA propusesse sua proibição; e após novo estudo, agora com supervisão do Congresso Norte-Americano, essa proibição foi retirada, porém com dose recomendada. Estudos em humanos, com uso intenso dessa substância, não comprovaram a associação entre seu uso e câncer. O limite de consumo, quando a sacarina recebeu o certificado de segura, em1955, é de 500 mg/dia para crianças e 1.000 mg/dia para adultos. Entretanto, o consumo diário varia, em média, de 25 a 125 mg/dia para não-diabéticos e de 54 a 173 mg/dia para diabéticos. Atualmente, a sacarina é aprovada em mais de 90 países sendo amplamente utilizada em muitos medicamentos e em alimentos [Fatibello- Filho O, Vieira ID, Gouveia ST, Calafatti AS, Guarita-Santos AJM. Artificial sweeteners. Química Nova 19:248- 260, 1996]. [019] Saccharin is the oldest and comes from methylanthranilate, a substance that appears naturally in grapes. It was discovered in 1875 by Constantin Fahlberg, from John Flopkins University, while studying the oxidation of sulfonamides (o-toluenesulfanamide), substances obtained from petroleum derivatives [Kroger M, Meister K, Kava R. Low-calorie Sweeteners and Other Sugar Substitutes: A Review of the Safety Issues. Comprehensive Reviews in Food Science and Food Safety 5: 35-47, 2006]. It is about 300 times sweeter than sucrose, heat-stable and non-cardiogenic. It has a long half-life, but has a residual metallic / bitter taste. It is not metabolized in the human digestive system, is rapidly excreted in the urine and does not accumulate in the human body. The acceptable daily intake is 3.5 mg / kg. Studies showing a weak association between high-dose consumption and cancer in rats led the FDA to propose its ban in 1977; and after a new study, now under the supervision of the North American Congress, this ban was lifted, but with a recommended dose. Studies in humans, with intense use of this substance, did not prove the association between its use and cancer. The consumption limit, when saccharin received the insurance certificate in 1955, is 500 mg / day for children and 1,000 mg / day for adults. However, daily consumption varies, on average, from 25 to 125 mg / day for non-diabetics and from 54 to 173 mg / day for diabetics. Currently, saccharin is approved in more than 90 countries and is widely used in many medicines and foods [Fatibello-Filho O, Vieira ID, Gouveia ST, Calafatti AS, Guarita-Santos AJM. Artificial sweeteners. Química Nova 19: 248- 260, 1996].
[020] O ciclamato é composto pelo ácido ciclo-hexil-sufâmico e foi descoberto em 1937 por Michael Sveda, da Universidade de Illinois. A descoberta da sua propriedade de conferir sabor doce foi atribuída a uma contaminação acidental de cigarro com um derivado da cicloexilamina. Seu poder adoçante é pequeno quando comparado com outros adoçantes, somente 30 vezes maior que o da sacarose. É usado em associação com a sacarina, combinando o alto poder adoçante da sacarina com a ausência de sabor residual do ciclamato. A FDA proibiu desde 1970 e virtude da existência de estudos mostrando associação com câncer. Até então, acreditava-se que sua absorção pelo organismo era lenta e parcial e que era eliminado de forma rápida e inalterada, com mínima ação toxica [Collings AJ. Metabolism of cyclamate and its conversion to cyclohexylamine. Sugar and Sweeteners. Boca Raton: CRC Press, p.217-227. 1991]. Porém, a segurança do ciclamato começou a ser questionada após observação em 1966, de que alguns indivíduos eram capazes de metabolizar ciclamato a cicloexilamina e de que a ingestão crónica de misturas de ciclamato, sacarina e cicloexilamina aumentava a incidência de tumores na bexiga de ratos [Collings AJ. Metabolism of cyclamate and its conversion to cyclohexylamine. Sugar and Sweeteners. Boca Raton: CRC Press, p.217- 227, 1991 ; Fernandez LAR. Edulcorantes intensos en la Comunidad Europea Alimentaria, Madrid, 27(216): 17-21, 1990]. Avaliações posteriores feitas pelo (Comité de Avaliação de Câncer), (Centro de Segurança Alimentar e Nutrição Aplicada), FDA, (Comité Científico para Alimentos), União Europeia e Organização Mundial da Saúde concluíram que o ciclamato não é carcinogênico e foi readmitido no mercado de alimentos. A ingestão diária aceitável é de 11 mg/kg. [020] Cyclamate is composed of cyclohexyl-sufamic acid and was discovered in 1937 by Michael Sveda, from the University of Illinois. The discovery of its sweet taste property was attributed to accidental contamination of cigarettes with a cyclohexylamine derivative. Its sweetening power is small when compared to other sweeteners, only 30 times greater than that of sucrose. It is used in combination with saccharin, combining the high sweetening power of saccharin with the absence of residual cyclamate flavor. The FDA has banned it since 1970 and because of the existence of studies showing an association with cancer. Until then, it was believed that its absorption by the organism was slow and partial and that it was eliminated quickly and unchanged, with minimal toxic action [Collings AJ. Metabolism of cyclamate and its conversion to cyclohexylamine. Sugar and Sweeteners. Boca Raton: CRC Press, p.217-227. 1991]. However, the safety of cyclamate began to be questioned after observation in 1966 that some individuals were able to metabolize cyclamate to cyclohexylamine and that chronic intake of cyclamate, saccharin and cyclohexylamine mixtures increased the incidence of tumors in the bladder of rats [ Collings AJ. Metabolism of cyclamate and its conversion to cyclohexylamine. Sugar and Sweeteners. Boca Raton: CRC Press, p.217-227, 1991; Fernandez LAR. Intense sweeteners in the European Food Community, Madrid, 27 (216): 17-21, 1990]. Subsequent assessments by the (Cancer Assessment Committee), (Center for Food Safety and Applied Nutrition), FDA, (Scientific Committee for Food), the European Union and the World Health Organization concluded that cyclamate is not carcinogenic and has been readmitted to the market of food. The acceptable daily intake is 11 mg / kg.
[021] O aspartame foi descoberto em 1965 e é o metil éster de dois aminoácidos (L- aspartato e L-fenilalanina). A síntese do aspartame, assim como a grande maioria dos edulcorantes, foi acidental. Nos anos 60, um dos projetos da G.D Searl and Company (Skokie Illinois), era encontrar um inibidor para gastrina, produto utilizado no tratamento de úlcera. O pesquisador James M. Schalatter aquecia aspartame em um frasco contendo metanol quando a mistura espirrou para fora do frasco e caiu-lhe nos dedos. Minutos após, levando o dedo a boca para folhear um livro, sentiu um sabor extremamente doce [Mazur, R. H. Discovery of aspartame. In L. D. Stegink & L. J. Filer (Eds.), Aspartame: Physiology and biochemistry (pp. 3-9). New York: Mareei Dekker, 1984]. É cerca de 200 vezes mais doce que a sacarose. Fornece cerca de 4 kcal/g, porém são necessárias quantidades muito pequenas para atingir o sabor adocicado desejado e, portanto, a caloria agregada é insignificante. A metabolização do aspartame no intestino dá origem a três componentes comuns da dieta: ácido aspártico, fenilalanina e metanol, e, portanto, está contraindicado para pacientes com fenilcetonúria. Estudos com animais de laboratório mostraram que o aspartame não apresenta nenhum efeito indutor de câncer, mesmo em altas doses. A ingestão diária aceitável é de 40mg/kg [ADA Reports. Position of the American Dietetic Association: use of nutritive and non-nutritive sweeteners. J Am Diet Assoe 104 (2):255-75, 2004. Erratum in: J Am Diet Assoe 104(6):1013, 2004]. [021] Aspartame was discovered in 1965 and is the methyl ester of two amino acids (L-aspartate and L-phenylalanine). The synthesis of aspartame, like the vast majority of sweeteners, was accidental. In the 60s, one of the projects of GD Searl and Company (Skokie Illinois), was to find an inhibitor for gastrin, a product used in the treatment of ulcers. Researcher James M. Schalatter was heating aspartame in a flask containing methanol when the mixture splashed out of the flask and fell on his fingers. Minutes later, taking his finger to his mouth to leaf through a book, he felt an extremely sweet taste [Mazur, RH Discovery of aspartame. In LD Stegink & LJ Filer (Eds.), Aspartame: Physiology and biochemistry (pp. 3-9). New York: Maree Dekker, 1984]. It is about 200 times sweeter than sucrose. It provides about 4 kcal / g, but very small amounts are needed to achieve the desired sweet taste and therefore the added calorie is negligible. The metabolism of aspartame in the intestine gives rise to three common components of the diet: aspartic acid, phenylalanine and methanol, and therefore is contraindicated for patients with phenylketonuria. Studies with laboratory animals have shown that aspartame has no cancer-inducing effect, even at high doses. The acceptable daily intake is 40mg / kg [ADA Reports. Position of the American Dietetic Association: use of nutritive and non-nutritive sweeteners. J Am Diet Assoe 104 (2): 255-75, 2004. Erratum in: J Am Diet Assoe 104 (6): 1013, 2004].
[022] A acesulfame K ou acesulfame potássio foi descoberta em 1967, na Alemanha. Trata-se de um sal orgânico constituído de carbono, nitrogénio, oxigénio, hidrogénio, enxofre e potássio. É cerca de 200 vezes mais doce que a sacarose, tendo sinergismo com outros adoçantes. Tem estabilidade ao calor, podendo ser usado em cozimentos e assados. Não apresenta gosto residual prolongado, porém isso pode acontecer em altas doses [Kroger M, Meister K, Kava R. Low-calorie Sweeteners and Other Sugar Substitutes: A Review of the Safety Issues. Comprehensive Reviews in Food Science and Food Safety 5:35-47, 2006; Cantarelli M, Pellerano RG, Marchevsky EJ, Camina JM. Simultaneous determination of aspartame and acesulfame-K by molecular absorption spectrophotometry using multivariate calibration and validation by high performance liquid chromatography. Analytical Methods Food Chemistry 115:1128-1132, 2009]. Estudos comprovaram que este edulcorante não possui potencial carcinogênico, não apresenta efeitos farmacológicos, mutagênicos ou teratogênicos [Cantarelli M, Pellerano RG, Marchevsky EJ, Camina JM. Simultaneous determination of aspartame and acesulfame-K by molecular absorption spectrophotometry using multivariate calibration and validation by high performance liquid chromatography. Analytical Methods Food Chemistry 115:1128-1132, 2009]. Após a ingestão, passa sem modificações pelo sistema digestivo, sendo, portando, não calórico. A dose diária máxima aceitável é de 15 mg/kg/dia. [022] Acesulfame K or acesulfame potassium was discovered in 1967 in Germany. It is an organic salt consisting of carbon, nitrogen, oxygen, hydrogen, sulfur and potassium. It is about 200 times sweeter than sucrose, having synergism with other sweeteners. It has heat stability and can be used in cooking and baking. It has no prolonged aftertaste, but this can happen in high doses [Kroger M, Meister K, Kava R. Low-calorie Sweeteners and Other Sugar Substitutes: A Review of the Safety Issues. Comprehensive Reviews in Food Science and Food Safety 5: 35-47, 2006; Cantarelli M, Pellerano RG, Marchevsky EJ, Camina JM. Simultaneous determination of aspartame and acesulfame-K by molecular absorption spectrophotometry using multivariate calibration and validation by high performance liquid chromatography. Analytical Methods Food Chemistry 115: 1128-1132, 2009]. Studies have shown that this sweetener does not have a carcinogenic potential, has pharmacological, mutagenic or teratogenic effects [Cantarelli M, Pellerano RG, Marchevsky EJ, Camina JM. Simultaneous determination of aspartame and acesulfame-K by molecular absorption spectrophotometry using multivariate calibration and validation by high performance liquid chromatography. Analytical Methods Food Chemistry 115: 1128-1132, 2009]. After ingestion, it passes unmodified through the digestive system, being therefore non-caloric. The maximum acceptable daily dose is 15 mg / kg / day.
[023] A sucralose, foi sintetizada em um laboratório da Universidade de Londres, em 1976. É um derivado da sacarose, com substituição de três grupos hidroxila por cloro, tendo pouca absorção, e a pouca quantidade absorvida não é metabolizada para produção de energia. Após vários estudos, a sucralose mostrou-se segura, não estando associada ao desenvolvimento de câncer, não provocando alterações genéticas, defeitos congénitos, lesão neurológica ou qualquer outra alteração metabólica, mesmo em dose acima de 500 mg/kg/dia. Não provoca resposta insulínica e vários estudos mostraram que é segura ao meio ambiente, sendo biodegradável. É cerca de 400 a 800 vezes mais doce que a sacarose. Em decorrência da sua solubilidade na água e estabilidade, a sucralose pode ser utilizada em vários alimentos e bebidas industrializadas. A ingestão máxima aceitável é de cerca de 15 mg/kg/dia [ADA Reports. Position of the American Dietetic Association: use of nutritive and non-nutritive sweeteners. J Am Diet Assoe 104 (2):255-75, 2004. Erratum in: J Am Diet Assoe 104(6):1013, 2004]. [023] Sucralose was synthesized in a laboratory at the University of London in 1976. It is a derivative of sucrose, with replacement of three hydroxyl groups by chlorine, having little absorption, and the small amount absorbed is not metabolized for energy production . After several studies, sucralose proved to be safe, not being associated with the development of cancer, causing no genetic alterations, birth defects, neurological damage or any other metabolic alteration, even at a dose above 500 mg / kg / day. It does not cause an insulin response and several studies have shown that it is safe for the environment, being biodegradable. It is about 400 to 800 times sweeter than sucrose. Due to its solubility in water and stability, sucralose can be used in various industrialized foods and drinks. The maximum acceptable intake is about 15 mg / kg / day [ADA Reports. Position of the American Dietetic Association: use of nutritive and non-nutritive sweeteners. J Am Diet Assoe 104 (2): 255-75, 2004. Erratum in: J Am Diet Assoe 104 (6): 1013, 2004].
[024] O alitame é formado por dois aminoácidos (ácido aspártico e alanina) e um amido, que é o principal responsável pelo alto poder adoçante, cerca de 2.000 vezes maior que a sacarose. Tem estabilidade em altas temperaturas e em grandes variações de pH e é altamente solúvel na água. Vários estudos mostram a sua segurança, mesmo em dose acima de 100 mg/kg/dia, dose cerca de 300 vezes maior que a dose habitual de usuários crónicos [ADA Reports. Position of the American Dietetic Association: use of nutritive and non-nutritive sweeteners. J Am Diet Assoe 104 (2):255-75, 2004. Erratum in: J Am Diet Assoe 104(6):1013, 2004]. [025] O esteviosídeo é obtido da planta Estevia rebaudiana Bertoni, pertencente a família das Compositae, originária das Américas, onde é usada como planta medicinal no controle de diabetes. Trata-se de uma substância temolábil, não carcinogênica e que não é metabolizada pelo organismo. Tem cerca de 300 vezes o poder adoçante em relação à sacarose. As folhas dessa planta têm sido utilizadas há séculos pela população nativa como adoçante. As substâncias associadas ao sabor adocicado são nove glicosídeos, chamados de glicosídeos estevióis. Dependendo das técnicas de cultivo e de crescimento, a quantidade desses glicosídeos varia de 4% a 20% de peso seco. O esteviosídeo e o rebaudiosídeo A são os mais abundantes entre os nove glicosídeos. O rebaudiosídeo A é considerado como o que tem as melhores propriedades organolépticas de adoçante e apresenta o menor sabor residual. Vários estudos mostraram a segurança toxicológica dessas substâncias. Em decorrência disso, os extratos contendo esteviosídeos estão liberados no Japão, Brasil, Coréia do Sul, Argentina e Paraguai e usados como suplementos dietéticos nos EUA. Ainda não foram liberados na União Européia, porém receberam o reconhecimento de GRAS, reconhecido como seguro nos EUA desde 2008. O Comité da FAO/OMS para aditivos alimentares sugere a ingestão diária aceitável de até 4mg/kg [ADA Reports. Position of the American Dietetic Association: use of nutritive and non- nutritive sweeteners. J Am Diet Assoe 104 (2):255-75, 2004. Erratum in: J Am Diet Assoe 104(6):1013, 2004]. [024] Alitame is formed by two amino acids (aspartic acid and alanine) and a starch, which is the main responsible for the high sweetening power, about 2,000 times greater than sucrose. It has stability at high temperatures and wide pH variations and is highly soluble in water. Several studies show its safety, even at a dose above 100 mg / kg / day, a dose about 300 times higher than the usual dose for chronic users [ADA Reports. Position of the American Dietetic Association: use of nutritive and non-nutritive sweeteners. J Am Diet Assoe 104 (2): 255-75, 2004. Erratum in: J Am Diet Assoe 104 (6): 1013, 2004]. [025] Stevioside is obtained from the plant Estevia rebaudiana Bertoni, belonging to the Compositae family, originally from the Americas, where it is used as a medicinal plant in the control of diabetes. It is a temolabile substance, non-carcinogenic and which is not metabolized by the body. It has about 300 times the sweetening power compared to sucrose. The leaves of this plant have been used for centuries by the native population as a sweetener. The substances associated with the sweet taste are nine glycosides, called steviole glycosides. Depending on cultivation and growth techniques, the amount of these glycosides varies from 4% to 20% dry weight. Stevioside and rebaudioside A are the most abundant among the nine glycosides. Rebaudioside A is considered to have the best organoleptic sweetener properties and has the least residual flavor. Several studies have shown the toxicological safety of these substances. As a result, extracts containing steviosides are released in Japan, Brazil, South Korea, Argentina and Paraguay and used as dietary supplements in the USA. They have not yet been released in the European Union, but have received GRAS recognition, recognized as safe in the USA since 2008. The FAO / WHO Committee for Food Additives suggests an acceptable daily intake of up to 4mg / kg [ADA Reports. Position of the American Dietetic Association: use of nutritive and non- nutritive sweeteners. J Am Diet Assoe 104 (2): 255-75, 2004. Erratum in: J Am Diet Assoe 104 (6): 1013, 2004].
[026] A Taumatina é proteína vegetal de cadeia longa naturalmente contida na fruta Katemfe. Essa proteína apresenta propriedades e benefícios únicos: é a substância mais doce de toda a Natureza (em média 3 mil vezes mais doce que o açúcar), um potente realçador de sabor/aroma e tem a capacidade de mascarar sabores residuais indesejáveis (como, por exemplo, o amargo e o metálico) de inúmeras substâncias, incluindo adoçantes artificiais (ciclamato, sacarina, acessulfame etc.), estévia, soja, minerais, vitaminas, substâncias de uso farmacêutico/médico, entre outros. Diversos estudos científicos e toxicológicos demonstram a inocuidade da taumatina à saúde do homem. Portanto, pode ser consumida por todos, incluindo os diabéticos, fenilcetonúricos, gestantes etc., sem restrições a qualquer grupo populacional. Devido a esses fatos, a taumatina é aprovada como GRAS (Generally Recognized As Safe”) nos Estados Unidos e é aprovada na Europa, Canadá, Japão e muitos outros países. Além disso, a taumatina consiste em um adoçante 100% natural e estável. A taumatina é o único adoçante de alta intensidade aprovado sem limite máximo de uso (quantum satis) pela ANVISA [Daniell WF. Katemfe, or the miraculous fruit of Soudan. Pharm J 14, 158, 1855; Eaton KK, Daniel JW, Snodin DJ, Higginbotham JD, Stanworth DR, Al-Mosawie T. Thaumatin protein: Assessment in man for oal allergenicity on challenge testing, 1981 ; Higginbotham JD, Snodin DJ, Eaton K.K., Daniel JW. Safety Evaluation of Thaumatin. Fd. Chem. Toxicol., 21, 815-823, 1983]. [026] Thaumatin is a long-chain vegetable protein naturally contained in the Katemfe fruit. This protein has unique properties and benefits: it is the sweetest substance in all of Nature (on average 3,000 times sweeter than sugar), a potent flavor / aroma enhancer and has the ability to mask unwanted residual flavors (such as example, bitter and metallic) of numerous substances, including artificial sweeteners (cyclamate, saccharin, acesulfame etc.), stevia, soy, minerals, vitamins, substances for pharmaceutical / medical use, among others. Several scientific and toxicological studies demonstrate that thaumatin is harmless to human health. Therefore, it can be consumed by everyone, including diabetics, phenylketonurics, pregnant women, etc., without restrictions to any population group. Due to these facts, thaumatin is approved as GRAS (Generally Recognized As Safe ”) in the United States and is approved in Europe, Canada, Japan and many other countries. In addition, thaumatin consists of a 100% natural and stable sweetener. Thaumatin is the only high intensity sweetener approved with no maximum use limit (quantum satis) by ANVISA [Daniell WF. Katemfe, or the miraculous fruit of Soudan. Pharm J 14, 158, 1855; Eaton KK, Daniel JW, Snodin DJ, Higginbotham JD, Stanworth DR, Al-Mosawie T. Thaumatin protein: Assessment in man for oal allergenicity on challenge testing, 1981; Higginbotham JD, Snodin DJ, Eaton KK, Daniel JW. Safety Evaluation of Thaumatin. Fd. Chem. Toxicol., 21, 815-823, 1983].
[027] O advantame é um novo adoçante artificial desenvolvido pela empresa Ajinomoto e é extremamente potente, sendo 20.000 vezes mais doce que a sacarose e 100 vezes mais doce que o aspartame. É derivado do aspartame, sendo um adoçante dipeptídico composto por ácido aspártico, fenilalanina e vanilina. Tem sabor doce próximo ao do açúcar, sem gosto residual. É estável em condições secas e na forma aquosa a estabilidade é similar ao aspartame. Em 2009 foi solicitada a aprovação para uso nos EUA ao FDA. Tem zero calorias [Bishay IE, Bursey RG. Advantame. In: 0'Brien Nabors L. Alternative sweeteners. 4th ed. Boca Raton, Fl: CRC; 2011]. [027] Advantame is a new artificial sweetener developed by the company Ajinomoto and is extremely potent, being 20,000 times sweeter than sucrose and 100 times sweeter than aspartame. It is derived from aspartame, being a dipeptide sweetener composed of aspartic acid, phenylalanine and vanillin. It has a sweet taste close to that of sugar, without residual taste. It is stable in dry conditions and in aqueous form the stability is similar to aspartame. In 2009, the FDA was approved for use in the United States. It has zero calories [Bishay IE, Bursey RG. Advantame. In: O'Brien Nabors L. Alternative sweeteners. 4th ed. Boca Raton, Fl: CRC; 2011].
[028] Além desses adoçantes descritos, outros adoçantes de alta potência de origem vegetal podem ser utilizados, conforme demonstrado por 0’Donnell e Kearsley [0’Donnell k, Kearsley, M. Sweeteners and sugar alternatives in food technology/edited by Kay 0’Donnell, Malcolm Kearsley. - 2nd ed. 2012], mas não somente estritos a esses, como exemplo: a) Proteínas: Brazzeína, curculina, monelina, bryoside, etc; b) Glicosídeos: rubusosídeo, osladina, pterocariosídoe, Lo han guo, etc; c) Flavonóide Filodulcina, Chalcona filozina etc. [028] In addition to these described sweeteners, other high-potency sweeteners of plant origin can be used, as shown by O'Donnell and Kearsley [O'Donnell k, Kearsley, M. Sweeteners and sugar alternatives in food technology / edited by Kay 0 'Donnell, Malcolm Kearsley. - 2nd ed. 2012], but not only strict to these, as an example: a) Proteins: Brazzeína, curculina, monelina, bryoside, etc; b) Glycosides: rubusoside, osladina, pterocariosidoe, Lo han guo, etc; c) Flavonoid Philodulcin, Chalcona phyllozine, etc.
[029] Os edulcorantes artificiais pertencem a classe de aditivos para alimentos cujo uso no Brasil e em outros países é limitado por legislação específica. Os critérios estabelecidos são emitidos em nível mundial por comités especializados [Toledo MCF, lOSHII SH. Potential intake of intense sweeteners in Brazil. Food Additives and Contaminants 12(6): 799-808, 1995]. O Programa FAO/OMS (Organização para a Alimentação e Agricultura das Nações Unidas/Organização Mundial da Saúde) para aditivos tem como objetivo avaliar sistematicamente e fornecer subsídios para que os países membros possam controlar o emprego dos aditivos em alimentos [IPCS (INTERNATION PROGRAMME ON CHEMICAL SAFETY), 2011. About IPCS INCHEM. Disponível em :<http://www.inchem.org/pages/about.html>. Acesso em maio de 2019]. O comité que avalia os aditivos é o Comité da FAO/OMS de Peritos em Aditivos Alimentares (JECFA), o qual é formado por um grupo internacional de peritos que são selecionados, principalmente, pela sua capacidade e experiencia técnica. Estes especialistas se reúnem periodicamente e discutem sobre assuntos técnicos e científicos, estabelecem especificações para a identidade e pureza de aditivos, avaliam dados toxicológicos e recomendam, quando apropriado, ingestões diárias aceitáveis (IDA) para as pessoas, sujeitas a revisões regulares [IPCS (INTERNATION PROGRAMME ON CHEMICAL SAFETY), 2011. About IPCS INCHEM. Disponível em :<http://www.inchem.org/pages/about.html>. Acesso em maio de 2019]. [029] Artificial sweeteners belong to the class of food additives whose use in Brazil and other countries is limited by specific legislation. The established criteria are issued worldwide by specialized committees [Toledo MCF, lOSHII SH. Potential intake of intense sweeteners in Brazil. Food Additives and Contaminants 12 (6): 799-808, 1995]. The FAO / WHO Program (Food and Agriculture Organization of the United Nations / World Health Organization) for additives aims to systematically assess and provide subsidies for member countries to control the use of additives in food [IPCS (INTERNATION PROGRAMME ON CHEMICAL SAFETY), 2011. About IPCS INCHEM. Available at: <http://www.inchem.org/pages/about.html>. Accessed in May 2019]. The committee that evaluates additives is the FAO / WHO Committee of Experts in Food Additives (JECFA), which is formed by an international group of experts who are selected mainly for their capacity and technical experience. These experts meet regularly and discuss technical and scientific issues, establish specifications for the identity and purity of additives, assess toxicological data and recommend, where appropriate, acceptable daily intakes (IDA) for people, subject to regular reviews [IPCS (INTERNATION PROGRAMME ON CHEMICAL SAFETY), 2011. About IPCS INCHEM. Available at: <http://www.inchem.org/pages/about.html>. Accessed in May 2019].
[030] A IDA é uma estimativa da quantidade de um aditivo que pode ser ingerida diariamente, e por toda a vida, pelo homem, sem risco apreciável a saúde. E expressa em miligramas de aditivo por quilograma de peso corpóreo (mg/kg p.c.) [CAC (Codex Alimentarius Comission), 1989. Report of the twenty-first session of the Codex Committee on Food Additives and Contaminants. Codex Alimentarius Comission, Food and Agriculture Organization of the United Nations, ALINORM 89/12A, Roma, 1989]. A ingestão potencial de um aditivo se refere a sua ingestão provável, resultante dos limites máximos permitidos para o seu uso em diferentes alimentos e bebidas e dos hábitos alimentares da população. Estimativas da ingestão diária de um determinado aditivo são, portanto, calculadas com o objetivo de verificar se existe possibilidade de exposição excessiva dos consumidores a substância, sob as condições de uso propostas [Bar A, Wurtzen G. Assessing the use of additives in food: a reappraisal of the Danish Budget Method. Food Science and Technology 23(3): 193-202, 1990]. Estimativas de ingestão de aditivos alimentares são consideradas parte integrante do do processo de avaliação de risco adotado no âmbito do Codex Alimentarius. [030] IDA is an estimate of the amount of an additive that can be ingested daily, and for life, by man, without appreciable health risk. It is expressed in milligrams of additive per kilogram of body weight (mg / kg bw) [CAC (Codex Alimentarius Commission), 1989. Report of the twenty-first session of the Codex Committee on Food Additives and Contaminants. Codex Alimentarius Commission, Food and Agriculture Organization of the United Nations, ALINORM 89 / 12A, Rome, 1989]. The potential intake of an additive refers to its likely intake, resulting from the maximum limits allowed for its use in different foods and beverages and the eating habits of the population. Estimates of the daily intake of a particular additive are, therefore, calculated with the objective of verifying whether there is a possibility of excessive exposure of consumers to the substance, under the proposed conditions of use [Bar A, Wurtzen G. Assessing the use of additives in food: the reappraisal of the Danish Budget Method. Food Science and Technology 23 (3): 193-202, 1990]. Estimates of intake of food additives are considered an integral part of the risk assessment process adopted under the Codex Alimentarius.
[031] Para este tipo de estudo são necessárias informações sobre os níveis da substância de interesse presente nos alimentos que fazem parte da dieta e sobre a quantidade destes alimentos, consumida pela população [WHO (WORLD HEALTH ORGANIZATION), 2000. Evaluation of certain food additives. Technical Report Series 891. Geneva, 2000]. O único modo possível de averiguar se um consumidor está exposto a um risco seria medir precisamente a quantidade de aditivo presente no alimento a ser consumido e comparar com a IDA estabelecida para este aditivo. Medidas e cálculos deste tipo teriam de ser feitos para todos os alimentos em cada refeição em todos os dias da vida, o que é uma tarefa impossível. Tentativas para buscar uma resposta a este problema levaram ao desenvolvimento de cálculos de ingestão potencial de aditivos, através do uso de dados de seu consumo médio (Tabela 1) [Vetorazzi, G. Advance in the Safety Evaluation of Food Additives. Food Add Cont, London, v.4, n4, p.331-356, 1987]. [031] For this type of study, information is needed on the levels of the substance of interest present in the foods that are part of the diet and on the quantity of these foods, consumed by the population [WHO (WORLD HEALTH ORGANIZATION), 2000. Evaluation of certain food additives. Technical Report Series 891. Geneva, 2000]. The only possible way to ascertain whether a consumer is exposed to a risk would be to measure precisely the amount of additive present in the food to be consumed and to compare it with the IDA established for this additive. Measures and calculations of this type would have to be made for all foods at each meal on every day of life, which is an impossible task. Attempts to seek an answer to this problem have led to the development of calculations of potential additive intake, using data from their average consumption (Table 1) [Vetorazzi, G. Advance in the Safety Evaluation of Food Additives. Food Add Cont, London, v.4, n4, p.331-356, 1987].
[032] Tabela 1. Valores de Ingestão Diária Aceitável (IDA) para edulcorantes artificiais permitidos no Brasil estabelecidos pelo Comité FAO/OMS de Peritos em Aditivos Alimentares [JECFA - Joint Expert Committee on Food Additives and Contaminants, Sixty-ninth meeting, Rome, Italy, 17-26 June 2008].
Figure imgf000014_0001
Avaliação do consumo de alimentos e edulcorantes
[032] Table 1. Acceptable Daily Intake Values (IDA) for artificial sweeteners allowed in Brazil established by the FAO / WHO Committee of Experts in Food Additives [JECFA - Joint Expert Committee on Food Additives and Contaminants, Sixty-ninth meeting, Rome, Italy, 17-26 June 2008].
Figure imgf000014_0001
Evaluation of the consumption of food and sweeteners
[033] Os hábitos alimentares estão estreitamente relacionados aos aspectos culturais, antropológicos, socioeconômicos e psicológicos que envolvem o ambiente das pessoas [Fisberg RM, Marchioni DML, Colucci ACA. Avaliação do consumo alimentar e da ingestão de nutrientes na prática clínica. Arq Bras Endocrinol Metabol 53, n.5, 2009]. [033] Eating habits are closely related to cultural, anthropological, socioeconomic and psychological aspects that involve people's environment [Fisberg RM, Marchioni DML, Colucci ACA. Evaluation of food consumption and nutrient intake in clinical practice. Arq Bras Endocrinol Metabol 53, n.5, 2009].
[034] Segundo Cândido e Campos [Cândido LM B, Campos AM. Alimentos para Fins Especiais: Dietéticos. São Paulo: Livraria Varela, 1996] os atributos de um adoçante ideal devem ser: [034] According to Cândido and Campos [Cândido LM B, Campos AM. Food for Special Purposes: Dietetic. São Paulo: Livraria Varela, 1996] the attributes of an ideal sweetener should be:
- Poder adoçante igual ou superior ao da sacarose; - Sweetening power equal to or greater than sucrose;
- Disponibilidade comercial; - Commercial availability;
- Custo comparável ao da sacarose; - Cost comparable to that of sucrose;
- Compatibilidade química com aditivos, como aromatizantes e corantes; - Chemical compatibility with additives, such as flavorings and dyes;
- Inerte aos demais componentes dos alimentos; - Inert to other food components;
- Fácil solubilidade, estabilidade química e térmica; - Easy solubility, chemical and thermal stability;
- Isento de toxicidade; - Free of toxicity;
- Não ser cariogênico; - Do not be cariogenic;
- Contribuir com calorias reduzidas; - Contribute with reduced calories;
- Proporcionar as propriedades funcionais, qualidade de doçura, sabor residual e perfil de doçura versus tempo semelhante ao da sacarose. - Provide functional properties, sweetness quality, residual flavor and sweetness profile versus sucrose-like time.
[035] De modo geral, nenhum edulcorante preenche todos os requisitos citados acima e, em vista disto, a utilização de combinações de edulcorantes é uma forma de compensar as limitações individuais de cada um deles, proporcionando o desenvolvimento de produtos com melhor sabor, maior vida útil e, muitas vezes, com custos de formulação reduzidos [WORLD HEALTH ORGANIZATION), 2000. Evaluation of certain food additives. Technic Report Ser 891. Geneva, 2000]. [035] In general, no sweetener fulfills all the requirements mentioned above and, in view of this, the use of sweetener combinations is a way to compensate for the individual limitations of each one, providing the development of products with better flavor, greater useful life and often with reduced formulation costs [WORLD HEALTH ORGANIZATION), 2000. Evaluation of certain food additives. Technic Report Ser 891. Geneva, 2000].
[036] O uso de edulcorantes em alimentos, bebidas e adoçantes de mesa tem crescido muito. A combinação deles apresenta diversas vantagens, tais como o aumento da estabilidade da doçura e o efeito de sinergismo, aumentando o poder adoçante. Em consequência, a combinação traz benefícios as indústrias, tais como a melhoria na qualidade da doçura (as combinações podem reduzir efeitos indesejáveis de alguns edulcorantes) e a obtenção de edulcorantes com características similares à sacarose[036] The use of sweeteners in food, drinks and table sweeteners has grown a lot. The combination of them has several advantages, such as the increase in sweetness stability and synergism effect, increasing the sweetening power. As a result, the combination brings benefits to industries, such as improving the quality of sweetness (combinations can reduce the undesirable effects of some sweeteners) and obtaining sweeteners with characteristics similar to sucrose
[Lim H, Setser CS, Kim SS. Sensory studies of high potency multiple sweeteners systems for shortbread cookies with and without polydextrose. Journal of Food Science 54(3): 625-629, 1989; Lindley MG. From basic research on sweetness to the development of sweeteners. Food Technol 47: 134-138, 1991]. [Lim H, Setser CS, Kim SS. Sensory studies of high potency multiple sweeteners systems for shortbread cookies with and without polydextrose. Journal of Food Science 54 (3): 625-629, 1989; Lindley MG. From basic research on sweetness to the development of sweeteners. Food Technol 47: 134-138, 1991].
[037] A combinação mais comumente encontrada é a mistura de ciclamato com sacarina, pois o efeito sinérgico entre estes edulcorantes proporciona um perfil de doçura mais próximo ao da sacarose, já que o ciclamato máscara o sabor amargo da sacarina [Zygler A, Wasik A, Namiesnik J. Analytical methodologies for determination of artificial sweeteners in foodstuffs. Trend Analyt Chem 28: 9, 2009]. [037] The most commonly found combination is the mixture of cyclamate with saccharin, since the synergistic effect between these sweeteners provides a sweetness profile closer to that of sucrose, since cyclamate masks the bitter taste of saccharin [Zygler A, Wasik A , Namiesnik J. Analytical methodologies for determination of artificial sweeteners in foodstuffs. Trend Analyt Chem 28: 9, 2009].
[038] O Aspartame, o Ciclamato de Sódio e a Sacarina Sódica, pioneiros no mercado, conhecidos como adoçantes dietéticos de primeira geração, até meados dos anos 80 eram considerados medicamentos e usados principalmente por diabéticos, a partir de 1988 houve uma reclassificação e eles se tornaram alimentos para fins especiais aumentando seu uso para a população em geral. [038] Aspartame, Sodium Cyclamate and Saccharin Sodium, pioneers in the market, known as first-generation dietary sweeteners, until the mid-1980s were considered medicines and used mainly by diabetics, since 1988 there was a reclassification and they became food for special purposes, increasing its use for the general population.
[039] Porém, de acordo com a ANVISA, e por conterem substâncias químicas em suas formulações, é necessário que se tenha alguns cuidados no uso, e, principalmente, nos excessos, pois em geral são os mais utilizados pela população, bem como, pelas gestantes. [039] However, according to ANVISA, and because they contain chemical substances in their formulations, it is necessary to have some care in the use, and, especially, in the excesses, because in general they are the most used by the population, as well as, by pregnant women.
[040] Geralmente, os adoçantes dietéticos são utilizados sem muito critério, e muitos dos seus usuários visam principalmente, a vaidade mais do que suas reais necessidades. Estes são normalmente utilizados por iniciativa própria, algumas vezes por indicações aleatórias ou simplesmente pela praticidade do uso. A minoria usa com recomendações médica ou de nutricionista. [040] Generally, dietary sweeteners are used without much discretion, and many of their users mainly aim at vanity more than their real needs. These are usually used on their own initiative, sometimes by random indications or simply for practical use. The minority uses it with medical or nutritionist recommendations.
[041] Há uma tendência mundial onde as pessoas estão cada dia mais atentas ao mercado e a procura de produtos mais saudáveis, inovadores e seguros para sua dieta, o que torna essa experiência ao mesmo tempo desafiadora, criteriosa e necessária. No mercado existem designações como produtos diet e light, indicados para quem precisa manter dietas restritivas ao açúcar, hábitos alimentares saudáveis ou está preocupado com a estética, porém esses produtos são muitas vezes mal interpretados pelo consumidor, uma vez que só o termo em si não dá créditos ao produto, definindo o que ele realmente é. [041] There is a global trend where people are increasingly attentive to the market and the demand for healthier, innovative and safer products for your diet, which makes this experience both challenging, judicious and necessary. In the market there are designations such as diet and light products, indicated for those who need to maintain sugar-restricted diets, healthy eating habits or are concerned with aesthetics, however these products are often misinterpreted by the consumer, since only the term itself does not gives credits to the product, defining what it really is.
[042] Neste cenário, apresentamos uma alternativa inovadora no mercado que permite ao produto adoçante proposto, características singulares que permite que o consumidor exigente, que não abre mão do sabor do açúcar, possa consumi-lo de uma forma mais saudável e com menos calorias. [042] In this scenario, we present an innovative alternative on the market that allows the proposed sweetening product, unique characteristics that allows the demanding consumer, who does not give up the taste of sugar, to consume it in a healthier way and with less calories .
SUMÁRIO DA INVENÇÃO SUMMARY OF THE INVENTION
[043] A presente invenção prevê um novo método de produção de adoçantes, obtendo-se uma formulação que preserve o sabor do açúcar, mas com redução de calorias, partindo-se da sacarose invertida e blendas com edulcorantes preferencialmente naturais ou sintéticos. [043] The present invention provides a new method of producing sweeteners, obtaining a formulation that preserves the taste of sugar, but with calorie reduction, starting from inverted sucrose and blends with preferably natural or synthetic sweeteners.
[044] Em uma primeira modalidade desta invenção apresenta-se uma composição com qualidade uniforme, pois sua composição depende de fonte de sacarose e edulcorantes, o que garante ao consumidor a segurança de um complemento alimentício de origem controlada, assegurando um alimento em consonância com as demandas específicas de cada tipo de consumidor. [044] In a first embodiment of this invention, a composition with uniform quality is presented, as its composition depends on a source of sucrose and sweeteners, which guarantees the consumer the safety of a food supplement of controlled origin, ensuring a food in line with the specific demands of each type of consumer.
[045] Em uma segunda modalidade a presente invenção, apresenta um processo de produção de um adoçante, partindo preferencialmente da matéria prima sacarose, ou seja, sacarose invertida, preferencialmente por meio de enzimas (não quimicamente) obtendo-se um xarope com partes equimolares de glicose e frutose e baixa concentração de sacarose e blendas com diversos tipos de edulcorantes. A presente invenção não fará uso da adição de substâncias químicas indesejáveis, como corantes e pigmentos artificiais e outros, podendo ser saborizado preferencialmente com aromas e aditivado com extratos naturais à base de plantas com reconhecida atividade farmacológica e/ou e substâncias com atividades funcionais. O processo conta ainda com o acréscimo opcional de elementos isolados, de fonte mineral ou vegetal como vitaminas, minerais etc. Desta forma, obtém-se uma formulação diferente dos adoçantes presentes no estado da técnica e no mercado. [045] In a second embodiment, the present invention presents a process for the production of a sweetener, preferably starting from the raw material sucrose, that is, inverted sucrose, preferably by means of enzymes (not chemically) obtaining a syrup with equimolar parts glucose and fructose and low concentration of sucrose and blends with different types of sweeteners. The present invention will not make use of the addition of undesirable chemical substances, such as dyes and artificial pigments and others, and can be preferably flavored with aromas and added with natural plant-based extracts with recognized pharmacological activity and / or substances with functional activities. The process it also has the optional addition of isolated elements, of mineral or vegetable source such as vitamins, minerals etc. In this way, a different formulation is obtained from the sweeteners present in the state of the art and on the market.
[046] A terceira e última modalidade desta invenção reside no uso do adoçante em produto de mesa e na indústria em geral, por exemplo em produtos derivados como bolos, doces, lácteos, cosméticos, geleias, doces, suplementos alimentares, fármacos, nutracêuticos, barras de cerais, entre outros. [046] The third and last modality of this invention resides in the use of the sweetener in table products and in the industry in general, for example in derivative products such as cakes, sweets, dairy products, cosmetics, jellies, sweets, food supplements, drugs, nutraceuticals, cereal bars, among others.
[047] A presente invenção, portanto, tem como base o xarope de sacarose invertida produzida sob medida para a produção de adoçante e aditivado de edulcorantes e outros. Para isso, o adoçante assim produzido pode ter como origem preferencial os açúcares escuros VHP/VVHP/Demerara/Mascavo ricos em minerais, vitaminas e antioxidantes naturais com grande apelo farmacológico, ofertando o dulçor e sabor natural do açúcar e aditivado com edulcorantes, sejam eles naturais ou sintéticos para aumentar o dulçor, o que acarreta na diminuição de quantidade de açúcar utilizado para adoçar, mas preservando o dulçor e sabor preservando as qualidades dos açúcares escuros. [047] The present invention, therefore, is based on inverted sucrose syrup made to measure for the production of sweetener and additive of sweeteners and others. For this, the sweetener thus produced may have as a preferential origin dark VHP / VVHP / Demerara / Brown sugars rich in minerals, vitamins and natural antioxidants with great pharmacological appeal, offering the sweetness and natural flavor of sugar and added with sweeteners, be they natural or synthetic to increase sweetness, which leads to a decrease in the amount of sugar used to sweeten, but preserving sweetness and flavor while preserving the qualities of dark sugars.
[048] Em outras palavras, os adoçantes aqui propostos usam açúcar invertido possuindo partes equimolares de glicose e frutose, e por esta razão o produto ganha dulçor com menos calorias, preferencialmente através de um processo totalmente natural, via biológica e GMO-free (tecnologia na qual não se faz uso de organismos geneticamente modificados) ou por enzimas comerciais e blendas com edulcorantes que potencializam o dulçor do produto, diminuindo a quantidade usada para o mesmo dulçor, assim como as calorias ingeridas. [048] In other words, the sweeteners proposed here use inverted sugar having equimolar parts of glucose and fructose, and for this reason the product gains sweetness with fewer calories, preferably through a totally natural process, via biological and GMO-free (technology which does not make use of genetically modified organisms) or by commercial enzymes and blends with sweeteners that enhance the sweetness of the product, reducing the amount used for the same sweetness, as well as the calories ingested.
DESCRIÇÃO DETALHADA DA INVENÇÃO DETAILED DESCRIPTION OF THE INVENTION
[049] A presente invenção descreve, portanto, COMPOSIÇÃO, PROCESSO DE PRODUÇÃO E USO DE ADOÇANTES NUTRITIVOS E BLENDAS baseados no açúcar invertido, atingindo uma composição que permite ao consumidor o prazer integral do sabor do açúcar, mas com redução significativa de calorias no produto, como exemplo, nas blendas com edulcorantes preferencialmente naturais. [049] The present invention therefore describes COMPOSITION, PROCESS OF PRODUCTION AND USE OF NUTRITIVE SWEETS AND BLENDS based on inverted sugar, reaching a composition that allows the consumer the full pleasure of the sugar flavor, but with a significant reduction of calories in the product , as an example, in blends with preferably natural sweeteners.
[050] Em função da possibilidade de utilização de edulcorantes naturais e sintéticos a presente invenção pode ter um índice glicêmico baixo (<= 55) em relação ao açúcar convencional. Além disso, o adoçante aqui proposto pode ser aditivado com extratos naturais de plantas como exemplo gengibre, canela, limão, romã, acerola, maracujá, mas não limitado somente a estes. Nesta proposta de aditivação com extratos naturais, os adoçantes passam a ter a funcionalidade farmacológica intrínseca de cada extrato, além de dar ao adoçante notas de sabor do extrato em particular, assim potencializando as qualidades dos açúcares escuros em atividades farmacológicas naturais as quais são preservadas quando se utiliza processo de inversão enzimática. [050] Depending on the possibility of using natural and synthetic sweeteners at the present invention may have a low glycemic index (<= 55) in relation to conventional sugar. In addition, the sweetener proposed here can be added with natural plant extracts such as ginger, cinnamon, lemon, pomegranate, acerola, passion fruit, but not limited to these only. In this additive proposal with natural extracts, the sweeteners now have the intrinsic pharmacological functionality of each extract, in addition to giving the sweetener flavor notes of the extract in particular, thus enhancing the qualities of dark sugars in natural pharmacological activities which are preserved when enzyme inversion process is used.
[051] Por exemplo, a utilização do açúcar VHP ou demerara ou Mascavo como base para fabricação do adoçante, permite que o produto tenha um conjunto importante de sais minerais, vitaminas e antioxidantes oriundos da cana de açúcar, como descrito no exemplo a seguir: [051] For example, the use of VHP or demerara or brown sugar as a base for the manufacture of the sweetener, allows the product to have an important set of mineral salts, vitamins and antioxidants from sugar cane, as described in the following example:
COMPOSIÇÃO A PARTIR DO AÇÚCAR VHP OU DEMERARA ORGÂNICOS OU CONVENCIONAIS COMPOSITION FROM VHP OR DEMERARA SUGAR ORGANIC OR CONVENTIONAL
[052] Em 100 gramas de açúcar VHP/Demerara/Mascavo há a presença de diversos minerais. Cabe aqui ressaltar que a composição mineral depende diretamente do tipo de cultivar de cana, do trato agronómico, região de cultivo etc. No entanto, diversos trabalhos mostram que quanto mais escuro, e obviamente, menos “tratado” o açúcar, mais minerais se conservam nele, conforme mostrado por Silva [Silva, AFS. Caracterização e determinação de minerais em amostras de açúcares brasileiros. Tese de Mestrado. ESALQ, USP, Piracicaba, 2017], conforme Tabela 2, a seguir. [052] In 100 grams of VHP / Demerara / Brown sugar there are the presence of several minerals. It is worth mentioning that the mineral composition depends directly on the type of cane cultivar, the agronomic tract, the region of cultivation, etc. However, several studies show that the darker, and obviously, the less “treated” the sugar, the more minerals are conserved in it, as shown by Silva [Silva, AFS. Characterization and determination of minerals in Brazilian sugar samples. Master's thesis. ESALQ, USP, Piracicaba, 2017], as shown in Table 2, below.
[053] Tabela 2: Faixa de concentração obtida para os minerais analisados por Espectrometria de Emissão Atómica por Plasma Acoplado Indutivamente (ICP OES) nos diferentes tipos de açúcar [Silva, AFS. Caracterização e determinação de minerais em amostras de açúcares brasileiros. Tese de Mestrado. ESALQ, USP, Piracicaba, 2017].
Figure imgf000019_0001
Figure imgf000020_0001
[053] Table 2: Concentration range obtained for the minerals analyzed by Inductively Coupled Plasma Atomic Emission Spectrometry (ICP OES) in different types of sugar [Silva, AFS. Characterization and determination of minerals in Brazilian sugar samples. Master's thesis. ESALQ, USP, Piracicaba, 2017].
Figure imgf000019_0001
Figure imgf000020_0001
[054] Conforme indicado na Tabela 2, os açúcares mais escuros apresentam teores de minerais crescentes, caminhando do açúcar refinado para o mascavo. Mesmo quando se compara o açúcar Demerara com o Refinado, observamos uma diferença significativa no teor de todos minerais apresentados na Tabela 2. [054] As shown in Table 2, darker sugars have increasing mineral contents, moving from refined to brown sugar. Even when comparing Demerara sugar with Refined sugar, we observed a significant difference in the content of all minerals presented in Table 2.
[055] Quanto maior for o conhecimento sobre a exata composição de cada um dos açúcares que se pode utilizar como base para o adoçante, maior é o poder de seleção da matéria-prima mais adequada para a produção do adoçante rico como alimento ou apresentando as propriedades organolépticas, físico-químicas e/ou sensoriais desejadas. Neste sentido, a escolha da fonte de sacarose ideal é imprescindível e um diferencial tecnológico para que o adoçante da presente invenção forneça ao consumidor qualidade superior em termos de minerais, compostos com ação farmacológicas e principalmente preservando o sabor tradicionalmente aceito do açúcar com diminuição de calorias, mas mantendo o dulçor. [055] The greater the knowledge about the exact composition of each of the sugars that can be used as a basis for the sweetener, the greater the power of selection of the most suitable raw material for the production of the rich sweetener as a food or presenting the desired organoleptic, physical-chemical and / or sensory properties. In this sense, the choice of the ideal sucrose source is essential and a technological differential so that the sweetener of the present invention provides the consumer with superior quality in terms of minerals, compounds with pharmacological action and mainly preserving the traditionally accepted taste of sugar with reduced calories. , but maintaining the sweetness.
[056] Para melhor ilustrar as melhorias acima descritas, o adoçante da presente invenção poderá conter compostos farmacológicos, por exemplo, aqueles presentes nos açúcares VHP, Demerara e Mascavo, tais como flavonóides e ácidos fenólicos como luteolina, apigenina, tricina, quercetina, kamferol, ácido cafeico, apigenina, luteolina, tricina, ácido clorogênico, ácido cumárico e ácido ferúlico. Estes compostos estão diretamente ligados a diversas atividades farmacológicas tais como antioxidantes, anti-inflamatórias, antimicrobianos e até antitumorais presentes nos açúcares de cana [Valli V, Gomez-Caravaca A.M.; Dl Nunzio M., Danesi F, Caboni MF, Bordoni A. Sugar cane and sugar beet molasses, antioxidante- rich alternatives to refined sugar. J. Agri Food Chem, 2012, 60, 12508- 12515; Alves V.G, Souza AG, Chiavelli LUR, Ruiz ALTG, Carvalho JE, Pomini AM, Silva CC. Phenolic compounds and anticâncer activity of comercial sugarcane cultivated in Brazil. Na. Acad. Bras, Cienc. 2016, 88, 1201-1209; Taylor R P. Discovery of bioactive natural products from sugarcane. Master of Science Thesis. School of Environmental Science and Management, Southern Cross University, Lismore NSW, Austrália. 2018; Almeida JMD. Flavonóides e ácidos cinâmicos de cana-de-açúcar ( Saccharum officinarum L. - Poaceae) e seus produtos. Identificação e atividade antioxidante e antiproliferativa. Tese de Doutorado. Universidade de São Paulo, 2006]. [056] To better illustrate the improvements described above, the sweetener of the present invention may contain pharmacological compounds, for example, those present in VHP, Demerara and Brown sugars, such as flavonoids and phenolic acids such as luteolin, apigenin, tricine, quercetin, kamferol , caffeic acid, apigenin, luteolin, tricin, chlorogenic acid, cumaric acid and ferulic acid. These compounds are directly linked to several pharmacological activities such as antioxidants, anti-inflammatory, antimicrobial and even antitumor agents present in cane sugars [Valli V, Gomez-Caravaca AM; Dl Nunzio M., Danesi F, Caboni MF, Bordoni A. Sugar cane and sugar beet molasses, antioxidant- rich alternatives to refined sugar. J. Agri Food Chem, 2012, 60, 12508-12515; Alves VG, Souza AG, Chiavelli LUR, Ruiz ALTG, Carvalho JE, Pomini AM, Silva CC. Phenolic compounds and anticancer activity of comercial sugarcane cultivated in Brazil. At. Acad. Bras, Cienc. 2016, 88, 1201-1209; Taylor R P. Discovery of bioactive natural products from sugarcane. Master of Science Thesis. School of Environmental Science and Management, Southern Cross University, Lismore NSW, Australia. 2018; Almeida JMD. Flavonoids and cinnamic acids from sugar cane (Saccharum officinarum L. - Poaceae) and their products. Identification and antioxidant and antiproliferative activity. Doctoral thesis. University of São Paulo, 2006].
[057] A presente invenção apresenta, portanto, uma composição de um adoçante capaz de manter as propriedades farmacológicas dos açúcares escuros que demonstram auxiliar na manutenção do tônus muscular da parede do trato digestivo; melhoram a saúde do sistema nervoso; fortalecem a pele, unhas e cabelos; melhoram a funcionamento do fígado, aceleram cicatrização de lesões e previnem e tratam a anemia devido à presença de ferro. Esses atributos, dependendo da matéria prima e aditivos utilizados, permitem que o adoçante da presente invenção seja ímpar em oferecer ao consumidor a base e sabor do açúcar, mas com menos calorias por unidade de dulçor. [057] The present invention therefore presents a composition of a sweetener capable of maintaining the pharmacological properties of dark sugars that have been shown to assist in maintaining the muscle tone of the digestive tract wall; improve the health of the nervous system; strengthen skin, nails and hair; they improve the functioning of the liver, accelerate wound healing and prevent and treat anemia due to the presence of iron. These attributes, depending on the raw material and additives used, allow the sweetener of the present invention to be unique in offering the consumer the base and flavor of sugar, but with less calories per unit of sweetness.
[058] Adicionalmente, o processo da presente invenção realiza a inversão da sacarose elevando o dulçor da mesma do patamar de 100 (sacarose cristal) para 120 (xarope de sacarose com 98,0 % de inversão e com porções equimolares de glicose e frutose), com ganho de 20% no dulçor, considerando a mesma quantidade de sacarose, pois a frutose apresenta índice de dulçor superior à sacarose e glicose. [058] Additionally, the process of the present invention performs the inversion of sucrose by raising its sweetness from the level of 100 (crystal sucrose) to 120 (sucrose syrup with 98.0% inversion and with equimolar portions of glucose and fructose) , with a 20% gain in sweetness, considering the same amount of sucrose, since fructose has a sweetness index higher than sucrose and glucose.
[059] Na inversão proposta pela presente invenção, por exemplo, acima de 90%, a sacarose é quase que completamente convertida em partes equimolares de glicose e frutose, sem perder significativamente suas características nutricionais quanto às vitaminas, antioxidantes e minerais presentes antes de sua inversão. Por se tratar de um catalizador biológico, a enzima invertase (preferencialmente livre de organismos geneticamente modificados - GMO Free) ou enzima invertase não GMO-free, ao contrário da inversão química, não forma compostos tóxicos no processo de inversão, como por exemplo, o furfural. [059] In the inversion proposed by the present invention, for example, above 90%, the sucrose is almost completely converted to equimolar parts of glucose and fructose, without significantly losing its nutritional characteristics regarding vitamins, antioxidants and minerals present before its inversion. Because it is a biological catalyst, the enzyme invertase (preferably free of genetically modified organisms - GMO Free) or non-GMO-free invertase enzyme, unlike chemical inversion, does not form toxic compounds in the inversion process, such as, for example, furfural.
[060] Com um teor muito reduzido de sacarose residual, a opcional adição de fibras funcionais poderá permitir que o adoçante da presente invenção apresente um índice glicêmico considerado baixo (<55). O que o torna mais adequado às dietas que buscam evitar doenças, como diabetes e problemas de obesidade. [060] With a very low residual sucrose content, the optional addition of functional fibers may allow the sweetener of the present invention to have a glycemic index considered low (<55). What makes it more suitable for diets that seek to avoid diseases, such as diabetes and obesity problems.
[061] Para melhor ilustrar, apresenta-se abaixo as características deste adoçante feito a partir do açúcar Demerara, como exemplo, segundo a presente invenção: [061] To better illustrate, the characteristics of this sweetener made from Demerara sugar are shown below, as an example, according to the present invention:
Adoçante convencional ou orgânico, que dependerá da origem do açúcar Demerara utilizado; Conventional or organic sweetener, which will depend on the origin of the Demerara sugar used;
Produzido a partir de açúcar Demerara invertido em grande parte em porções equimolares de glicose e frutose; Produced from inverted Demerara sugar largely in equimolar portions of glucose and fructose;
Com adição de fibras funcionais, apresenta um índice glicêmico baixo (< 55); With the addition of functional fibers, it has a low glycemic index (<55);
Adoçante com poder antioxidante em função dos compostos poli-fenólicos dos açúcares escuros. Compostos que se mantém preservados no processo de inversão via enzimática; Sweetener with antioxidant power due to the polyphenolic compounds of dark sugars. Compounds that are preserved in the enzymatic inversion process;
Uso de enzimas GMO-free ou não; Use of GMO-free enzymes or not;
Processo 100% natural, sem conservantes artificiais ou qualquer aditivo químico; 100% natural process, without artificial preservatives or any chemical additives;
Possui potencial farmacológico devido às substâncias preservadas nos açúcares escuros como o Demerara; It has pharmacological potential due to substances preserved in dark sugars such as Demerara;
Podem ser adicionadas vitaminas, minerais, aminoácidos e fibras. Vitamins, minerals, amino acids and fibers can be added.
Processo de Produção do Adoçante. [062] De acordo com a presente invenção, uma das formas de produção do adoçante, inicia-se com a diluição da sacarose sólida, presente na fonte de carboidrato selecionada com água a um xarope de sacarose de 78,0 Q Brix e aquecida a 80QC para total dissolução da sacarose, sob agitação no tanque. Esse xarope é então resfriado a 55,0 a 60,0 QC e o pH acertado a 4,5 com uso de ácido cítrico. A enzima invertase, GMO-free ou comercial, é adicionada ao xarope e a reação é mantida até o tempo necessário para atingir a inversão desejada (maior de 90,0 % e até 98,0 %) da sacarose em glicose e frutose nas condições descritas, obtendo-se um xarope com partes equimolares de glicose e frutose e baixa concentração de sacarose, apresentando dulçor superior ao da sacarose não invertida, o que permite usar menos quantidade de produto em relação à sacarose naõ invertida para atingir o mesmo dulçor. O xarope pode ser aditivado com edulcorantes naturais ou sintéticos, fibras naturais, vitaminas, minerais, aminoácidos, aromas, extratos vegetais, substâncias funcionais, outros açúcares, entre outros. Sweetener Production Process. [062] According to the present invention, one of the ways of producing the sweetener, begins with the dilution of the solid sucrose, present in the selected carbohydrate source with water to a sucrose syrup of 78.0 Q Brix and heated to 80 Q C for total dissolution of sucrose, with agitation in the tank. This syrup is then cooled to 55.0 to 60.0 Q C and the pH adjusted to 4.5 with the use of citric acid. The invertase enzyme, GMO-free or commercial, is added to the syrup and the reaction is maintained until the time necessary to achieve the desired inversion (greater than 90.0% and up to 98.0%) of the sucrose in glucose and fructose under the conditions described, obtaining a syrup with equimolar parts of glucose and fructose and a low concentration of sucrose, presenting a higher sweetness than that of non-inverted sucrose, which allows to use less quantity of product in relation to non-inverted sucrose to achieve the same sweetness. The syrup can be added with natural or synthetic sweeteners, natural fibers, vitamins, minerals, amino acids, flavors, plant extracts, functional substances, other sugars, among others.
[063] De acordo com os estudos realizados, quando usamos o processo de obtenção anteriormente descrito, é possível obter um adoçante que possui as principais vantagens em relação aos adoçantes disponíveis no mercado: [063] According to the studies carried out, when we use the process of obtaining previously described, it is possible to obtain a sweetener that has the main advantages in relation to the sweeteners available on the market:
- Processo totalmente orgânico, sem aditivos químicos; - Totally organic process, without chemical additives;
- Sabor tradicional do açúcar com menos calorias nas blendas com edulcorantes, naturais ou sintéticos; - Traditional sugar flavor with less calories in blends with sweeteners, natural or synthetic;
- Fonte de fibras. A adição de fibras é um aspecto importante, pois permite a digestibilidade mais lenta dos carboidratos, evitando picos de insulina e melhorando a flora intestinal; - Fiber source. The addition of fiber is an important aspect, as it allows the slower digestibility of carbohydrates, avoiding insulin spikes and improving the intestinal flora;
- Conservação de potencial farmacológico devido ao uso de açúcares escuros como, por exemplo o uso de açúcares VHP ou Demerara ou Mascavo que apresentam na sua composição natural os compostos farmacologicamente ativos. - Preservation of pharmacological potential due to the use of dark sugars, such as the use of VHP or Demerara or Mascavo sugars, which contain pharmacologically active compounds in their natural composition.
[064] Entretanto, a presente invenção verificou que o adoçante, com estas e outras vantagens, pode ser obtido a partir de pequenas variações no processo acima descrito com diferentes tipos de sacarose e aditivos. Desta forma, para melhor ilustrar as diferentes formas de obtenção e tipos de sacarose, serão apresentados a seguir os exemplos ilustrativos de processos e composição do adoçante da presente invenção, sendo que os valores expressos nas Tabelas estão baseados em [Ajibola A., Chamunorwa JP, Erlwanger KH. Nutraceutical values of natural honey and its contribuition to human health and wealth. Nutrition & Metabolism 2012, 9:61 ; Faria DAM. Estudo Nutricional e sensorial de açúcares cristal, refinado, demerara e mascavo orgânicos e convencionais. Tese de Mestrado. UFSCAR, 2012; Luchini DL. Teores de nutrientes minerais e metais pesados em açúcar mascavo produzido por diferentes sistemas orgânicos e convencionais. Tese de Mestrado. UFSCAR, 2014; Moniruzzaman M, Chowdhury MAZ, Rahman MA, Sulaiman SA, Gan SH. Determination of mineral, trace elemento, and pesticide leveis in honey samples originating from diferente regions of Malaysia compared to Manuka Honey. Biomed. Res. Int. 2014, ID 359890; Nogueira FS, Ferreira KS, Carneiro Júnior JB, Passoni LC. Minerais em melados e em caldos de cana. Ciência e Tecnologia de Alimentos 2009, 29:727-731 ; Silva AFS. Caracterização e determinação de minerais em amostras de açúcares brasileiros. Tese de Mestrado. ESALQ, USP, Piracicaba, 2017]. [064] However, the present invention has found that the sweetener, with these and other advantages, can be obtained from small variations in the process described above with different types of sucrose and additives. Thus, in order to better illustrate the different ways of obtaining and types of sucrose, the following will be presented: illustrative examples of the processes and composition of the sweetener of the present invention, the values expressed in the Tables being based on [Ajibola A., Chamunorwa JP, Erlwanger KH. Nutraceutical values of natural honey and its contribution to human health and wealth. Nutrition & Metabolism 2012, 9:61; Would do DAM. Nutritional and sensory study of organic and conventional crystal, refined, demerara and brown sugars. Master's thesis. UFSCAR, 2012; Luchini DL. Content of mineral nutrients and heavy metals in brown sugar produced by different organic and conventional systems. Master's thesis. UFSCAR, 2014; Moniruzzaman M, Chowdhury MAZ, Rahman MA, Sulaiman SA, Gan SH. Determination of mineral, trace element, and light pesticide in honey samples originating from different regions of Malaysia compared to Manuka Honey. Biomed. Int. Res. 2014, ID 359890; Nogueira FS, Ferreira KS, Carneiro Júnior JB, Passoni LC. Minerals in molasses and sugarcane juice. Food Science and Technology 2009, 29: 727-731; Silva AFS. Characterization and determination of minerals in Brazilian sugar samples. Master's thesis. ESALQ, USP, Piracicaba, 2017].
[065] Exemplo 1 - Produção do adoçante a partir de açúcar cristal de cana invertido ENZIMATICAMENTE: [065] Example 1 - Production of the sweetener from inverted cane sugar ENZYMATICALLY:
1. Sacarose sólida é diluída com água a um xarope de sacarose de 78,0 Q Brix é aquecida a 80 QC para total dissolução do açúcar, sob agitação no tanque; 1. Solid sucrose is diluted with water to a sucrose syrup of 78.0 Q Brix and heated to 80 Q C for total dissolution of the sugar, with agitation in the tank;
2. O xarope é resfriado a 55,0 a 60,0 QC e o pH acertado a 4,5 com uso de ácido cítrico. Neste xarope a enzima invertase (GMO-free ou não) é adicionada conforme indicação de uso comercial e a reação é mantida pelo tempo necessário para garantir a porcentagem de inversão requerida; 2. The syrup is cooled to 55.0 to 60.0 Q C and the pH adjusted to 4.5 with the use of citric acid. In this syrup the enzyme invertase (GMO-free or not) is added according to the indication of commercial use and the reaction is maintained for the time necessary to guarantee the required inversion percentage;
3. O xarope é filtrado para retirada de particulados; 3. The syrup is filtered to remove particulates;
4. O xarope filtrado pode ser aditivado com edulcorantes, por exemplo EsEstevia, na concentração que permita que o xarope final tenha o dobro do dulçor e metade das calorias, podendo esta proporção ser alterada para maior ou menor conforme a necessidade. Exemplo, 1 Kg de xarope de açúcar invertido é aditivado com 2,6 g de EsEstevia, sendo que a EsEstevia é em média 300 x mais doce que a sacarose, tem-se que o produto (1 kg) fica com dulçor referente a 2 Kg de sacarose. Para ilustrar, temos o exemplo do uso de um sachê de 5 g de açúcar sacarose para adoçar um café tradicional, ou seja, no adoçante proposto seria utilizado 2,5 g do produto para adoçar o mesmo café com o mesmo dulçor dos 5g da sacarose pura, mas com metade das calorias. Da mesma forma, outros edulcorantes podem ser utilizados para aditivar o xarope, conforme seu poder de dulçor (Tabela 3). 4. The filtered syrup can be added with sweeteners, for example EsEstevia, in the concentration that allows the final syrup to have twice the sweetness and half the calories, and this proportion can be changed to greater or lesser as required. Example, 1 kg of inverted sugar syrup is added with 2.6 g of EsEstevia, with EsEstevia being on average 300 x sweeter than sucrose, the product (1 kg) has a sweetness of 2 Kg of sucrose. To illustrate, we have the example of using a sachet of 5 g of sucrose sugar to sweeten a traditional coffee, that is, in the proposed sweetener 2.5 g of the product would be used to sweeten the same coffee with the same sweetness of the 5 g of sucrose pure, but with half the calories. Likewise, other sweeteners can be used to add the syrup, according to its sweetening power (Table 3).
[066] Desta forma, o EXEMPLO 1 refere-se a: [066] Thus, EXAMPLE 1 refers to:
- uso de AÇÚCAR CRISTAL (podendo ser orgânico, não orgânico ou refinado) como base do adoçante da presente invenção; - use of CRYSTAL SUGAR (may be organic, non-organic or refined) as the basis of the sweetener of the present invention;
- invertido ENZIMATICAMENTE em diferentes taxas de inversão (relação sacarose/glicose+frutose: > 90% de inversão); - ENZYMATICALLY inverted at different inversion rates (sucrose / glucose + fructose ratio:> 90% inversion);
- Podendo ser aditivado com edulcorante natural ou sintético. - Can be added with natural or synthetic sweetener.
[067] Tabela 3: Exemplo comparativo do dulçor e calorias do adoçante proposto em sacarose cristal invertida.
Figure imgf000025_0001
Figure imgf000026_0001
[067] Table 3: Comparative example of the sweetener and calories of the proposed sweetener in inverted crystal sucrose.
Figure imgf000025_0001
Figure imgf000026_0001
* Considerando que o açúcar cristal sólido possui em média 387 Kcal por 100 g de produto e dulçor referência de 1 vez. * Considering that solid crystal sugar has an average of 387 Kcal per 100 g of product and sweetness reference once.
[068] Exemplo 2 - Produção do adoçante a partir de açúcar cristal de cana invertido QUIMICAMENTE: [068] Example 2 - Production of the sweetener from CHEMICALLY inverted cane sugar:
1. Sacarose sólida é diluída com água a um xarope de sacarose de 78,0 Q Brix e aquecida a 80 QC para total dissolução do açúcar, sob agitação intensa no tanque; 1. Solid sucrose is diluted with water to a sucrose syrup of 78.0 Q Brix and heated to 80 Q C for total dissolution of the sugar, under intense agitation in the tank;
- Adiciona-se ácido fosfórico no xarope até pH 2,0 a 2,5, mantendo-se a 95 QC até a taxa de inversão desejada; - phosphoric acid is added to the syrup to pH 2.0 to 2.5 while maintaining at 95 Q C until the desired rate reversal;
2. O pH do xarope é corrigido com barrilha a pH 4,5 a 5,0; 2. The pH of the syrup is corrected with a wedge at pH 4.5 to 5.0;
3. O xarope é filtrado para retirada de particulados; 3. The syrup is filtered to remove particulates;
4. O xarope é filtrado para retirada de produtos indesejados; 4. The syrup is filtered to remove unwanted products;
5. O xarope filtrado pode ser aditivado com edulcorante, por exemplo Estevia, na concentração que permita que o xarope final tenha o dobro do dulçor e metade das calorias, podendo esta proporção ser alterada para maior ou menor conforme a necessidade. Exemplo, 1 Kg de xarope de açúcar invertido é aditivado com 3,3 g de Estevia, sendo que a Estevia é em média 300 x mais doce que a sacarose, tem-se que o produto (1Kg) fica com dulçor referente a 2 Kg de sacarose. Da mesma forma, outros edulcorantes podem ser utilizados para aditivar o xarope, conforme seu poder de dulçor (Tabela 4). 5. The filtered syrup can be added with sweetener, for example Estevia, in a concentration that allows the final syrup to have twice the sweetness and half the calories, and this proportion can be changed to greater or lesser as needed. Example, 1 Kg of inverted sugar syrup is added with 3.3 g of Estevia, being that Estevia is on average 300 x sweeter than sucrose, the product (1Kg) has a sweetness of 2 Kg of sucrose. Likewise, other sweeteners can be used to add the syrup, according to its sweetening power (Table 4).
[069] Desta forma, o EXEMPLO 2 refere-se a: [069] Thus, EXAMPLE 2 refers to:
- uso de AÇÚCAR CRISTAL (podendo ser orgânico, não orgânico ou refinado) como base do adoçante, conforme exemplo 1, porém sem uso de enzima; - use of CRYSTAL SUGAR (which may be organic, non-organic or refined) as the base of the sweetener, as shown in example 1, but without the use of an enzyme;
- invertido QUIMICAMENTE em diferentes taxas de inversão (relação sacarose/glicose+frutose: > 90% de inversão); - CHEMICALLY inverted at different inversion rates (sucrose / glucose + fructose ratio:> 90% inversion);
- Podendo ser aditivado com edulcorante natural ou sintético. - Can be added with natural or synthetic sweetener.
[070] Tabela 4: Exemplo comparativo do dulçor e calorias do adoçante proposto em sacarose cristal.
Figure imgf000027_0001
[070] Table 4: Comparative example of sweetness and calories of the proposed sweetener in crystal sucrose.
Figure imgf000027_0001
*Considerando que o açúcar cristal sólido possui em média 387 Kcal por 100 g de produto e dulçor referência de 1 vez. * Considering that solid crystal sugar has an average of 387 Kcal per 100 g of product and sweetness reference once.
[071] Cabe ressaltar que a inversão da sacarose pelo método tradicional químico o xarope inicial tem concentração máxima de 60 Q Brix devido a necessidade de filtrações para remoção de cor e odor, e após a inversão, o pH do xarope precisa ser corrigido com uso de barrilha, fato este que que satura o xarope com sulfatos indesejáveis e, sequencialmente, o xarope é filtrado e concentrado em evaporadores, o que diminui ainda mais a sua qualidade devido a formação adicional de substâncias indesejáveis como: furfural, hidrometilfurfural e principalmente sulfoximetilfurfural dadas as suas capacidades de reagir com o DNA e provocar mutações [Ogando FIB. Estudo da degradação térmica de sacarose e da contaminação microbiológica no processo de fabricação de açúcar. Teses de Mestrado, ESALQ/USP, 2015]. [072] Exemplo 3 - Produção do adoçante a partir de açúcar cristal de cana orgânico invertido QUIMICAMENTE seguindo a Lista Positiva de Orgânicos: [071] It should be noted that the inversion of sucrose by the traditional chemical method the initial syrup has a maximum concentration of 60 Q Brix due to the need for filtration to remove color and odor, and after the inversion, the pH of the syrup needs to be corrected with use of soda, a fact that saturates the syrup with undesirable sulfates and, sequentially, the syrup is filtered and concentrated in evaporators, which further decreases its quality due to the additional formation of undesirable substances such as: furfural, hydromethylfurfural and mainly sulfoxymethylfurfural given their ability to react with DNA and cause mutations [Ogando FIB. Study of sucrose thermal degradation and microbiological contamination in the sugar manufacturing process. Master's Theses, ESALQ / USP, 2015]. [072] Example 3 - Sweetener production from CHEMICALLY inverted organic cane sugar following the Positive Organic List:
1. Sacarose sólida é diluída com água a um xarope de sacarose de 78,0 Q Brix e aquecida a 80 QC para total dissolução do açúcar, sob agitação intensa no tanque; 1. Solid sucrose is diluted with water to a sucrose syrup of 78.0 Q Brix and heated to 80 Q C for total dissolution of the sugar, under intense agitation in the tank;
2. Adiciona-se ácido no xarope até pH 2,0 a 2,5, mantendo-se a 95 QC até a taxa de inversão desejada. O ácido usado neste processo deve estar permitido pela Lista Positiva de Orgânicos (Instrução normativa nQ 18, de 28 de maio de 2009, Lei 10,831 de 23 de dezembro de 2003): exemplo ácido cítrico; 2. Add the syrup acid to pH 2.0 to 2.5 while maintaining at 95 Q C until the desired rate of inversion. The acid used in this process must be allowed by the Positive Organic List (Normative Instruction Q 18, of May 28, 2009, Law 10,831 of December 23, 2003): example citric acid;
3. pH do xarope é corrigido com produtos permitidos pela Lista Positiva de Orgânicos (Instrução normativa nQ 18, de 28 de maio de 2009, Lei 10,831 de 23 de dezembro de 2003), a pH 4,5 a 5,0; 3. The syrup's pH is corrected with products allowed by the Positive Organic List (Normative Instruction Q 18, of May 28, 2009, Law 10.831 of December 23, 2003), at pH 4.5 to 5.0;
4. O xarope é filtrado para retirada de particulados; 4. The syrup is filtered to remove particulates;
5. O xarope filtrado pode ser aditivado com edulcorante, por exemplo Estevia, na concentração que permita que o xarope final tenha o dobro do dulçor e metade das calorias, podendo esta proporção ser alterada para maior ou menor conforme a necessidade. Exemplo, 1 Kg de xarope de açúcar invertido é aditivado com 2,6 g de Estevia, sendo que a Estevia é em média 300 x mais doce que a sacarose, tem-se que o produto (1Kg) fica com dulçor referente a 2 Kg de sacarose. Da mesma forma, outros edulcorantes podem ser utilizados para aditivar o xarope, conforme seu poder de dulçor (Tabela 5). 5. The filtered syrup can be added with sweetener, for example Estevia, in a concentration that allows the final syrup to have twice the sweetness and half the calories, and this proportion can be changed to greater or lesser as needed. Example, 1 Kg of inverted sugar syrup is added with 2.6 g of Estevia, being that Estevia is on average 300 x sweeter than sucrose, the product (1Kg) has a sweetness of 2 Kg of sucrose. Likewise, other sweeteners can be used to add the syrup, according to its sweetening power (Table 5).
[073] Desta forma, o EXEMPLO 3 refere -se a: [073] Thus, EXAMPLE 3 refers to:
- uso de AÇÚCAR CRISTAL ORGÂNICO como base do adoçante, conforme exemplo 2, porém fazendo uso da lista positiva de orgânicos; - use of ORGANIC CRYSTAL SUGAR as the basis of the sweetener, as shown in example 2, but using the positive organic list;
- invertido QUIMICAMENTE com produtos permitidos pela Lista Positiva de Orgânicos em diferentes taxas de inversão (relação sacarose/glicose+frutose: > 90% de inversão), sendo considerado um xarope orgânico; - CHEMICALLY inverted with products allowed by the Positive Organic List at different inversion rates (sucrose / glucose + fructose ratio:> 90% inversion), being considered an organic syrup;
- Podendo ser aditivado com edulcorante natural ou sintético. - Can be added with natural or synthetic sweetener.
[074] Tabela 5: Exemplo comparativo do dulçor e calorias do adoçante proposto em sacarose cristal invertida.
Figure imgf000029_0002
[074] Table 5: Comparative example of sweetness and calories of the proposed sweetener in inverted crystal sucrose.
Figure imgf000029_0002
* Considerando que o açúcar cristal
Figure imgf000029_0001
possui em média 387 Kcal por 100 g de produto e dulçor referência de 1 vez.
* Whereas crystal sugar
Figure imgf000029_0001
it has an average of 387 Kcal per 100 g of product and a sweetness reference of 1 time.
[075] Exemplo 4 - Produção do adoçante a partir de açúcar VHP ou VVHP: [075] Example 4 - Production of the sweetener from VHP or VVHP sugar:
1. Sacarose VVHP (Very Very High Polarization) ou VHP (Very High Polarization) sólida é diluída com água a um xarope de sacarose de 78,0 Q Brix e aquecida a 80 QC para total dissolução do açúcar, sob agitação no tanque; 1. VVHP (Very Very High Polarization) sucrose or solid VHP (Very High Polarization) is diluted with water in a sucrose syrup of 78.0 Q Brix and heated to 80 Q C for total dissolution of the sugar, under agitation in the tank;
2. O xarope é invertido QUIMICAMENTE (produtos orgânicos ou não) ou ENZIMATICAMENTE como descrito nos exemplos anteriores; 2. The syrup is inverted CHEMICALLY (organic products or not) or ENZYMATICALLY as described in the previous examples;
3. O xarope é filtrado para retirada de particulados; 3. The syrup is filtered to remove particulates;
4. O xarope filtrado pode ser aditivado com edulcorante, por exemplo Estevia, na concentração que permita que o xarope final tenha o dobro do dulçor e metade das calorias, podendo esta proporção ser alterada para maior ou menor conforme a necessidade. Exemplo, 1 Kg de xarope de açúcar invertido é aditivado com 2,6 g de Estevia, sendo que a Estevia é em média 300 x mais doce que a sacarose, tem-se que o produto (1Kg) fica com dulçor referente a 2 Kg de sacarose. Da mesma forma, outros edulcorantes podem ser utilizados para aditivar o xarope, conforme seu poder de dulçor (Tabela 6). 4. The filtered syrup can be added with sweetener, for example Estevia, in a concentration that allows the final syrup to have twice the sweetness and half the calories, and this proportion can be changed to greater or lesser as needed. Example, 1 kg of inverted sugar syrup is added with 2.6 g of Estevia, with Estevia being on average 300 x sweeter than sucrose, there is that the product (1Kg) is sweet with 2 kg of sucrose. Likewise, other sweeteners can be used to add the syrup, according to its sweetening power (Table 6).
[076] Desta forma, o EXEMPLO 4 refere-se a: [076] Thus, EXAMPLE 4 refers to:
- uso de açúcares VHP ou VVHP (orgânicos ou não) como base do adoçante;- use of VHP or VVHP sugars (organic or not) as a sweetener base;
- invertidos QUIMICAMENTE ou ENZIMATICAMENTE em diferentes taxas de inversão (relação sacarose/glicose+frutose: > 90% de inversão); - CHEMICALLY or ENZYMATICALLY inverted at different inversion rates (sucrose / glucose + fructose ratio:> 90% inversion);
- Podendo ser aditivado com edulcorante natural ou sintético. - Can be added with natural or synthetic sweetener.
[077] Tabela 6: Exemplo comparativo do dulçor e calorias do adoçante proposto e sacarose VVHP ou VHP invertidos.
Figure imgf000030_0001
[077] Table 6: Comparative example of the sweetener and calories of the proposed sweetener and sucrose VVHP or inverted VHP.
Figure imgf000030_0001
* Considerando que o açúcar VHP sólido possui em média 380 Kcal por 100 g de produto e dulçor referência de 1 vez. * Considering that solid VHP sugar has an average of 380 Kcal per 100 g of product and sweetness reference once.
[078] Exemplo 5 - Produção do adoçante a partir de açúcar Demerara: [078] Example 5 - Production of sweetener from Demerara sugar:
1. Sacarose Demerara sólida é diluída com água a um xarope de sacarose de 78,0 Q Brix e aquecida a 80 Q C para total dissolução do açúcar, sob agitação no tanque; 1. Solid Demerara sucrose is diluted with water to a sucrose syrup of 78.0 Q Brix and heated to 80 Q C for total dissolution of the sugar, with agitation in the tank;
2. O xarope é invertido QUIMICAMENTE (produtos orgânicos ou não) ou ENZIMATICAMENTE como descrito nos exemplos anteriores; 2. The syrup is inverted CHEMICALLY (organic products or not) or ENZYMATICALLY as described in the previous examples;
3. O xarope é filtrado para retirada de particulados; 3. The syrup is filtered to remove particulates;
4. O xarope filtrado pode ser aditivado com edulcorante, por exemplo Estevia, na concentração que permita que o xarope final tenha o dobro do dulçor e metade das calorias, podendo esta proporção ser alterada para maior ou menor conforme a necessidade. Exemplo, 1 Kg de xarope de açúcar invertido é aditivado com 2,6 g de Estevia, sendo que a Estevia é em média 300 x mais doce que a sacarose, tem-se que o produto fica com dulçor referente a 2 Kg de sacarose. Da mesma forma, outros edulcorantes podem ser utilizados para aditivar o xarope, conforme seu poder de dulçor (Tabela 7). 4. The filtered syrup can be added with sweetener, for example Estevia, in a concentration that allows the final syrup to have twice the sweetness and half the calories, and this proportion can be changed to greater or lesser as needed. For example, 1 kg of inverted sugar syrup is added with 2.6 g of Estevia, with Estevia being on average 300 x sweeter than sucrose, the product has a sweetness of 2 kg of sucrose. Likewise, other sweeteners can be used to add the syrup, according to its sweetening power (Table 7).
[079] Desta forma, o EXEMPLO 5 refere-se a: [079] Thus, EXAMPLE 5 refers to:
- uso de açúcares DEMERARA (orgânico ou não) como base do adoçante;- use of DEMERARA sugars (organic or not) as a base for the sweetener;
- invertidos QUIMICAMENTE ou ENZIMATICAMENTE em diferentes taxas de inversão (relação sacarose/glicose+frutose: > 90% de inversão), - CHEMICALLY or ENZYMATICALLY inverted at different inversion rates (sucrose / glucose + fructose ratio:> 90% inversion),
- podendo ser aditivado com edulcorante natural ou sintético; - can be added with natural or synthetic sweetener;
[080] Tabela 7: Exemplo comparativo do dulçor e calorias do adoçante proposto em sacarose Demerara invertida.
Figure imgf000031_0001
Figure imgf000032_0001
[080] Table 7: Comparative example of the sweetener and calories of the proposed sweetener in inverted Demerara sucrose.
Figure imgf000031_0001
Figure imgf000032_0001
* Considerando que o açúcar Demerara possui em média 380 Kcal por 100 g de produto e dulçor referência de 1 vez. * Considering that Demerara sugar has an average of 380 Kcal per 100 g of product and sweetness reference once.
[081] Exemplo 6 - Produção do adoçante a partir de açúcar Mascavo: [081] Example 6 - Sweetener production from brown sugar:
1. Açúcar Mascavo sólido é diluído com água a um xarope de sacarose de 78, 0Q Brix e aquecida a 80 Q C para total dissolução do açúcar, sob agitação no tanque; 1. Solid brown sugar is diluted with water to a sucrose syrup of 78.0 Q Brix and heated to 80 Q C for total dissolution of the sugar, with agitation in the tank;
2. O xarope é invertido QUIMICAMENTE (produtos orgânicos ou não) ou ENZIMATICAMENTE como descrito nos exemplos anteriores; 2. The syrup is inverted CHEMICALLY (organic products or not) or ENZYMATICALLY as described in the previous examples;
3. O xarope é filtrado para retirada de particulados; 3. The syrup is filtered to remove particulates;
4. O xarope filtrado pode ser aditivado com edulcorante, por exemplo Estevia, na concentração que permita que o xarope final tenha o dobro do dulçor e metade das calorias, podendo esta proporção ser alterada para maior ou menor conforme a necessidade. Exemplo, 1 Kg de xarope de açúcar invertido é aditivado com 2,6 g de Estevia, sendo que a Estevia é em média 300 x mais doce que a sacarose, tem-se que o produto fica com dulçor referente a 2 Kg de sacarose. Da mesma forma, outros edulcorantes podem ser utilizados para aditivar o xarope, conforme seu poder de dulçor (Tabela 8). 4. The filtered syrup can be added with sweetener, for example Estevia, in a concentration that allows the final syrup to have twice the sweetness and half the calories, and this proportion can be changed to greater or lesser as needed. For example, 1 kg of inverted sugar syrup is added with 2.6 g of Estevia, with Estevia being on average 300 x sweeter than sucrose, the product has a sweetness of 2 kg of sucrose. Likewise, other sweeteners can be used to add the syrup, according to its sweetening power (Table 8).
[082] Desta forma, o EXEMPLO 6 refere-se a: [082] Thus, EXAMPLE 6 refers to:
- uso de açúcares Mascavo (orgânico ou não) como base do adoçante; - use of brown sugars (organic or not) as a base for the sweetener;
- invertidos QUIMICAMENTE ou ENZIMATICAMENTE em diferentes taxas de inversão (relação sacarose/glicose+frutose: > 90% de inversão); - CHEMICALLY or ENZYMATICALLY inverted at different inversion rates (sucrose / glucose + fructose ratio:> 90% inversion);
- Podendo ser aditivado com edulcorante natural ou sintético. - Can be added with natural or synthetic sweetener.
[083] Tabela 8: Exemplo comparativo do dulçor e calorias do adoçante proposto e açúcar Mascavo.
Figure imgf000033_0001
[083] Table 8: Comparative example of the sweetener and calories of the proposed sweetener and brown sugar.
Figure imgf000033_0001
* Considerando que o açúcar Demerara possui em média 380 Kcal por 100 g de produto e dulçor referência de 1 vez. * Considering that Demerara sugar has an average of 380 Kcal per 100 g of product and sweetness reference once.
[084] Exemplo 7 - Produção do adoçante a partir de açúcar de beterraba, côco e outros: [084] Example 7 - Sweetener production from sugar beet, coconut and others:
1. Açúcar de beterraba, côco e outros é diluída com água a um xarope de sacarose de 78,0 Q Brix e aquecida a 80QC para total dissolução do açúcar, sob agitação intensa no tanque; 1. Sugar from beet, coconut and others is diluted with water to a sucrose syrup of 78.0 Q Brix and heated to 80 Q C for total dissolution of the sugar, under intense agitation in the tank;
2. O xarope é invertido QUIMICAMENTE (produtos orgânicos ou não) ou ENZIMATICAMENTE como descrito nos exemplos anteriores; 2. The syrup is inverted CHEMICALLY (organic products or not) or ENZYMATICALLY as described in the previous examples;
3. O xarope é filtrado para retirada de particulados; 3. The syrup is filtered to remove particulates;
4. O xarope filtrado pode ser aditivado com edulcorante, por exemplo Estevia, na concentração que permita que o xarope final tenha o dobro do dulçor e metade das calorias, podendo esta proporção ser alterada para maior ou menor conforme a necessidade. Exemplo, 1 Kg de xarope de açúcar invertido é aditivado com 2,6 g de Estevia, sendo que a Estevia é em média 300 x mais doce que a sacarose, tem-se que o produto fica com dulçor referente a 2 Kg de sacarose. Da mesma forma, outros edulcorantes podem ser utilizados para aditivar o xarope, conforme seu poder de dulçor (Tabela 9). 4. The filtered syrup can be added with sweetener, for example Estevia, in a concentration that allows the final syrup to have twice the sweetness and half the calories, and this proportion can be changed to greater or lesser as needed. For example, 1 kg of inverted sugar syrup is added with 2.6 g of Estevia, with Estevia being on average 300 x sweeter than sucrose, the product has a sweetness of 2 kg of sucrose. Gives similarly, other sweeteners can be used to add the syrup, according to its sweetening power (Table 9).
[085] Desta forma, o EXEMPLO 7 refere-se a: [085] Thus, EXAMPLE 7 refers to:
- uso do açúcar de beterraba, côco e outros (orgânicos ou não) como base do adoçante; - use of sugar beet, coconut and others (organic or not) as a base for the sweetener;
- invertidos QUIMICAMENTE ou ENZIMATICAMENTE em diferentes taxas de inversão (relação sacarose/glicose+frutose: > 90% de inversão); - CHEMICALLY or ENZYMATICALLY inverted at different inversion rates (sucrose / glucose + fructose ratio:> 90% inversion);
- Podendo ser aditivado com edulcorante natural ou sintético; - Can be added with natural or synthetic sweetener;
[086] Tabela 9: Exemplo comparativo do dulçor e calorias do adoçante proposto e açúcar de côco.
Figure imgf000034_0001
[086] Table 9: Comparative example of the sweetener and calories of the proposed sweetener and coconut sugar.
Figure imgf000034_0001
* Considerando que o açúcar de coco possui em média 380 Kcal por 100 g de produto e dulçor referência de 1 vez. * Considering that coconut sugar has an average of 380 Kcal per 100 g of product and sweetness reference once.
[087] Exemplo 8 - Produção do adoçante a partir dos diversos açúcares com adição de fibras: [087] Example 8 - Sweetener production from different sugars with added fibers:
1. Sacarose sólida de qualquer tipo de açúcar é diluída com água a um xarope de sacarose de 78,0 Q Brix e aquecida a 80 QC para total dissolução do açúcar, sob agitação no tanque; 1. Solid sucrose of any type of sugar is diluted with water in a syrup sucrose of 78.0 Q Brix and heated to 80 Q C for total dissolution of the sugar, with agitation in the tank;
2. O xarope é invertido QUIMICAMENTE (produtos orgânicos ou não) ou ENZIMATICAMENTE como descrito nos exemplos anteriores; 2. The syrup is inverted CHEMICALLY (organic products or not) or ENZYMATICALLY as described in the previous examples;
3. O xarope é filtrado para retirada de particulados; 3. The syrup is filtered to remove particulates;
4. O xarope filtrado pode ser aditivado com edulcorante conforme exemplos 1 a 7. 4. The filtered syrup can be added with sweetener according to examples 1 to 7.
5. O adoçante pode ser aditivado com: 5. The sweetener can be added with:
- 0,5 % a 20,0% de fibras solúveis orgânicas ou não, tais como, por exemplo: fibras do milho, polidextroses, maltodextrinas solúveis ou fibras de mandioca; - 0.5% to 20.0% of organic soluble fibers or not, such as, for example: corn fibers, polydextroses, soluble maltodextrins or cassava fibers;
- 0,5 % a 20,0% de fibras insolúveis orgânicas ou não, tais como, por exemplo fibras do milho ou mandioca ou de vegetais; - 0.5% to 20.0% of organic or non-insoluble fibers, such as, for example, corn or cassava or vegetable fibers;
- 1 ,0 % a 20,0% com fibras solúveis ou insolúveis na proporção de 1 ,0 a 99,0% de mistura entre os dois tipos de fibras - 1.0% to 20.0% with soluble or insoluble fibers in the proportion of 1.0 to 99.0% of mixture between the two types of fibers
[088] Desta forma, o EXEMPLO 8 refere-se a: [088] Thus, EXAMPLE 8 refers to:
- uso dos açúcares orgânicos ou não: Cristal, VHP, VVHP, DEMERARA, Mascavo, Côco, Beterraba, e outros como base do adoçante; - use of organic sugars or not: Cristal, VHP, VVHP, DEMERARA, Mascavo, Coconut, Beet, and others as a base for the sweetener;
- invertidos QUIMICAMENTE ou ENZIMATICAMENTE em diferentes taxas de inversão (relação sacarose/glicose+frutose: > 90% de inversão); - CHEMICALLY or ENZYMATICALLY inverted at different inversion rates (sucrose / glucose + fructose ratio:> 90% inversion);
- Podendo ser aditivado com edulcorante natural ou sintético; - Can be added with natural or synthetic sweetener;
- Podendo ser enriquecido com FIBRAS. - It can be enriched with FIBERS.
[089] O consumo adequado de fibras na dieta usual pode reduzir o risco de desenvolvimento de algumas doenças crónicas como: doença arterial coronariana [Liu[089] Adequate consumption of fiber in the usual diet can reduce the risk of developing some chronic diseases such as: coronary artery disease [Liu
S, Stampfer MJ, Hu FB, Giovannucci E, Rimm E, Manson JE, et al. Whole- grain consumption and risk of coronary heart disease: results from the Nurses’ Health study. Am J Clin Nutr 70(3) :412-9, 1999], acidente vascular cerebral (AVC) [Steffen LM, Jacobs DR Jr, Stevens J, Shahar E, CarithersS, Stampfer MJ, Hu FB, Giovannucci E, Rimm E, Manson JE, et al. Whole-grain consumption and risk of coronary heart disease: results from the Nurses ’Health study. Am J Clin Nutr 70 (3): 412-9, 1999], stroke (Steffen LM, Jacobs DR Jr, Stevens J, Shahar E, Carithers
T, Folsom AR. Associations of whole-grain, refined grain, and fruit and vegetable consumption with risks of all-cause mortality and incident coronary artery disease and ischemic stroke: the Atherosclerosis Risk in Communities (ARIC) Study. Am J Clin Nutr 78(3):383-90, 2003], hipertensão arterial [Whelton SP, Hyre AD, Pedersen B, Yi Y, Whelton PK, He J. Effect of dietary fiber intake on blood pressure: a meta-analysis of randomized, controlled clinicai trials. J Hypertens 23(3):475-81, 2005], diabetes melito [Montonen J, Knekt P, Jarvinen R, Aromaa A, Reunanen A. Whole-grain and fiber intake and the incidence of type 2 diabetes. Am J Clin Nutr 77(3):622-9, 2003] e algumas desordens gastrointestinais [Petruzziello L, lacopini F, Bulajic M, Shah S, Costamagna G. Review article: uncomplicated diverticular disease of the colon. Aliment Pharmacol Ther 23(10): 1379-91, 2006]. T, Folsom AR. Associations of whole-grain, refined grain, and fruit and vegetable consumption with risks of all-cause mortality and incident coronary artery disease and ischemic stroke: the Atherosclerosis Risk in Communities (ARIC) Study. Am J Clin Nutr 78 (3): 383-90, 2003], hypertension [Whelton SP, Hyre AD, Pedersen B, Yi Y, Whelton PK, He J. Effect of dietary fiber intake on blood pressure: a meta-analysis of randomized, controlled clinical trials. J Hypertens 23 (3): 475-81, 2005], diabetes mellitus [Montonen J, Knekt P, Jarvinen R, Aromaa A, Reunanen A. Whole-grain and fiber intake and the incidence of type 2 diabetes. Am J Clin Nutr 77 (3): 622-9, 2003] and some gastrointestinal disorders [Petruzziello L, lacopini F, Bulajic M, Shah S, Costamagna G. Review article: uncomplicated diverticular disease of the colon. Aliment Pharmacol Ther 23 (10): 1379-91, 2006].
[090] A fibra alimentar é resistente à ação das enzimas digestivas humanas e é constituída de polímeros de carboidratos, com três ou mais unidades monoméricas mais a lignina [Anderson JW, Baird P, Davis RH Jr, Ferreri S, Knudtson M, Koraym A, et ai. Health benefits of dietary fiber. Nutr Rev 67(4) :188-205, 2009; Howlett JF, Betteridge VA, Champ M, Craig SAS, Meheust A, Jones JM. The definition of dietary fiber - discussions at the Ninth Vahouny Fiber Symposium: building scientific agreement. Food Nutr Res 54:5750, 2010]. Os componentes da fibra alimentar dividem-se nos grupos: polissacarídeos não amido, oligossacarídeos, carboidratos análogos (amido resistente e maltodextrinas resistentes), lignina, compostos associados à fibra alimentar (compostos fenólicos, proteína de parede celular, oxalatos, fitatos, ceras, cutina e suberina) e fibras de origem animal (quitina, quitosana, colágeno e condroitina) [Tungland BC, Mayer D. Nondigestible oligo- and polysaccharides (dietary fiber): their physiology and role in human health and food. Comp Rev Food Sei Food Saf 1:73-92, 2002]. [090] Dietary fiber is resistant to the action of human digestive enzymes and consists of polymers of carbohydrates, with three or more monomeric units plus lignin [Anderson JW, Baird P, Davis RH Jr, Ferreri S, Knudtson M, Koraym A , et al. Health benefits of dietary fiber. Nutr Rev 67 (4): 188-205, 2009; Howlett JF, Betteridge VA, Champ M, Craig SAS, Meheust A, Jones JM. The definition of dietary fiber - discussions at the Ninth Vahouny Fiber Symposium: building scientific agreement. Food Nutr Res 54: 5750, 2010]. The components of dietary fiber are divided into groups: non-starch polysaccharides, oligosaccharides, analogous carbohydrates (resistant starch and resistant maltodextrins), lignin, compounds associated with dietary fiber (phenolic compounds, cell wall protein, oxalates, phytates, waxes, cutin and suberin) and animal fibers (chitin, chitosan, collagen and chondroitin) [Tungland BC, Mayer D. Nondigestible oligo- and polysaccharides (dietary fiber): their physiology and role in human health and food. Comp Rev Food Sci Food Saf 1: 73-92, 2002].
[091] Os efeitos positivos das fibras estão relacionados, em parte, ao fato de que uma parcela da fermentação de seus componentes ocorre no intestino grosso, o que produz impacto sobre a velocidade do trânsito intestinal, sobre o pH do cólon e sobre a produção de subprodutos com importante função fisiológica [DeVries JW. On defining dietary fibre. Proc Nutr Soc 46(3):112- 29, 2003]. Assim, as fibras concorrem para uma digestão equilibrada dos carboidratos, sendo considerado um importante aditivo alimentar. [091] The positive effects of fibers are related, in part, to the fact that a portion of the fermentation of its components occurs in the large intestine, which impacts on the speed of intestinal transit, on the pH of the colon and on production of by-products with an important physiological function [DeVries JW. On defining dietary fiber. Proc Nutr Soc 46 (3): 112-29, 2003]. Thus, the fibers contribute to a balanced digestion of carbohydrates, being considered an important food additive.
[092] Exemplo 9 - Produção do adoçante a partir dos diversos açúcares com adição de fibras e aminoácidos: [092] Example 9 - Sweetener production from different sugars with added fibers and amino acids:
1. Sacarose sólida de qualquer tipo de açúcar é diluída com água a um xarope de sacarose de 78,0 Q Brix e aquecida a 80 QC para total dissolução do açúcar, sob agitação intensa no tanque;2. O xarope é invertido QUIMICAMENTE (produtos orgânicos ou não) ou ENZIMATICAMENTE como descrito nos exemplos anteriores; 1. Solid sucrose of any type of sugar is diluted with water to a sucrose syrup of 78.0 Q Brix and heated to 80 Q C for total dissolution of the sugar, under intense agitation in the tank; 2. The syrup is inverted CHEMICALLY (organic products or not) or ENZYMATICALLY as described in the previous examples;
3. O xarope é filtrado para retirada de particulados; 3. The syrup is filtered to remove particulates;
4. O xarope filtrado pode ser aditivado com edulcorantes conforme exemplos 1 a 7; 4. The filtered syrup can be added with sweeteners according to examples 1 to 7;
5. O xarope pode ser aditivado com fibras; 5. The syrup can be added with fibers;
6. O xarope pode ser aditivado com diversos tipos de aminoácidos como por exemplo: ácido glutâmico, ácido aspártico, glutamina, histidina, glicina, treonina, alanina, arginina, prolina, tirosina, valina, metionina, cisteina, leucina, fenilalanina, isoleucina, triptofano, ornitina e lisina, entre outros, garantindo que no produto final, os diversos aminoácidos de interesse possam estar presentes. A recomendação diária de aminoácidos de cadeia ramificada para adultos segundo a FAO/OMS (2011) é de 20 mg/kg de isoleucina, 26 mg/kg de valina e 39 mg/kg de leucina. Por tanto, para cada aminoácido, é preciso avaliar o IDR (Ingestão Dietética de Referência) recomendado. 6. The syrup can be added with different types of amino acids such as: glutamic acid, aspartic acid, glutamine, histidine, glycine, threonine, alanine, arginine, proline, tyrosine, valine, methionine, cysteine, leucine, phenylalanine, isoleucine, tryptophan, ornithine and lysine, among others, ensuring that in the final product, the various amino acids of interest can be present. The daily recommendation for branched-chain amino acids for adults according to the FAO / WHO (2011) is 20 mg / kg of isoleucine, 26 mg / kg of valine and 39 mg / kg of leucine. Therefore, for each amino acid, it is necessary to evaluate the recommended RDI (Reference Dietary Intake).
[093] Desta forma, a reivindicação do EXEMPLO 9 refere-se a: [093] Thus, the claim of EXAMPLE 9 refers to:
- uso dos açúcares orgânicos ou não: Cristal, VHP, VVHP, DEMERARA, Mascavo, Côco, Beterraba, e outros como base do adoçante; - use of organic sugars or not: Cristal, VHP, VVHP, DEMERARA, Mascavo, Coconut, Beet, and others as a base for the sweetener;
- invertidos QUIMICAMENTE ou ENZIMATICAMENTE em diferentes taxas de inversão (relação sacarose/glicose+frutose: > 90% de inversão); - CHEMICALLY or ENZYMATICALLY inverted at different inversion rates (sucrose / glucose + fructose ratio:> 90% inversion);
- Podendo ser aditivado com Edulcorante natural ou sintético; - Can be added with natural or synthetic sweetener;
- Podendo ser enriquecido com FIBRAS; - It can be enriched with FIBERS;
- Podendo ser enriquecido com AMINOÁCIDOS. - It can be enriched with AMINO ACIDS.
[094] Exemplo 10 - Produção do adoçante a partir de açúcares dos diversos açúcares com adição de fibras, aminoácidos e aditivado de minerais: [094] Example 10 - Production of the sweetener from sugars of the different sugars with added fibers, amino acids and mineral additives:
1. Sacarose sólida de qualquer tipo de açúcar é diluída com água a um xarope de sacarose de 78,0 Q Brix e aquecida a 80 QC para total dissolução do açúcar, sob agitação no tanque; 1. Solid sucrose of any type of sugar is diluted with water to a sucrose syrup of 78.0 Q Brix and heated to 80 Q C for total dissolution of the sugar, with agitation in the tank;
2. O xarope é invertido QUIMICAMENTE (produtos orgânicos ou não) ou ENZIMATICAMENTE como descrito nos exemplos anteriores; 2. The syrup is inverted CHEMICALLY (organic products or not) or ENZYMATICALLY as described in the previous examples;
3. O xarope é filtrado para retirada de particulados; 3. The syrup is filtered to remove particulates;
4. O xarope filtrado pode ser aditivado com edulcorantes conforme exemplos4. The filtered syrup can be added with sweeteners as examples
1 a 7., 1 to 7.,
5. O adoçante pode ser aditivado com fibras, conforme Exemplo 8; 5. The sweetener can be added with fibers, according to Example 8;
6. O adoçante pode ser aditivado com aminoácidos conforme Exemplo 9; 6. The sweetener can be added with amino acids according to Example 9;
7. O adoçante pode ser aditivado tomando-se como referência a faixa a dose de ingestão diária de minerais de Zinco, Cálcio, Fósforo, Ferro e Magnésio indicadas para as diversas faixas etárias ou grupo de carências segundo Regulamento da ANVISA aprovado pelo Decreto nQ 3.029, de 16 de abril de 1999, c/c o art. 111, inciso I, alínea “e” do Regimento Interno aprovado pela Portaria nQ 593, de 25 de agosto de 2000, publicada no DOU de 22 de dezembro de 2000, em reunião realizada em 6 de dezembro de 2004. Outras regulamentações nacionais ou internacionais também poderão ser utilizadas como referência. Também outros minerais, como exemplo cobre, selênio, manganês e fósforo, podem ser adicionados dentro dos limites segundo as referências das diversas regulamentações. 7. The sweetener can be added using the daily intake dose of Zinc, Calcium, Phosphorus, Iron and Magnesium minerals as a reference to the range indicated for the different age groups or needs according to ANVISA Regulation approved by Decree n Q 3,029, of April 16, 1999, with art. 111, item I, item “e” of the Internal Regulations approved by Ordinance No. Q 593, of August 25, 2000, published in the DOU of December 22, 2000, in a meeting held on December 6, 2004. Other national regulations or international agreements can also be used as a Also other minerals, such as copper, selenium, manganese and phosphorus, can be added within the limits according to the references of the various regulations.
[095] Desta forma, o EXEMPLO 10 refere-se a: [095] Thus, EXAMPLE 10 refers to:
- uso dos açúcares orgânicos ou não: Cristal, VHP, VVHP, DEMERARA, Mascavo, Côco, Beterraba, e outros como base do adoçante; - use of organic sugars or not: Cristal, VHP, VVHP, DEMERARA, Mascavo, Coconut, Beet, and others as a base for the sweetener;
- invertidos QUIMICAMENTE ou ENZIMATICAMENTE em diferentes taxas de inversão (relação sacarose/glicose+frutose: > 90% de inversão); - CHEMICALLY or ENZYMATICALLY inverted at different inversion rates (sucrose / glucose + fructose ratio:> 90% inversion);
- Podendo ser aditivado com edulcorante natural ou sintético; - Can be added with natural or synthetic sweetener;
- Podendo ser enriquecido com FIBRAS; - It can be enriched with FIBERS;
- Podendo ser enriquecido com MINERAIS. - It can be enriched with MINERALS.
[096] Desta forma, o adoçante pode apresentar a composição conforme exemplo da Tabela 10. [096] In this way, the sweetener can present the composition as an example of Table 10.
[097] Tabela 10. Exemplo de composição do adoçante proposto com os aditivos e usando açúcar Demerara invertido (98% inversão) como xarope de base.
Figure imgf000039_0001
[097] Table 10. Example of composition of the proposed sweetener with the additives and using inverted Demerara sugar (98% inversion) as base syrup.
Figure imgf000039_0001
[098] Exemplo 11 - Produção do adoçante a partir de açúcares dos diversos açúcares com adição de fibras, aminoácidos, aditivado de minerais e vitaminas: [098] Example 11 - Production of the sweetener from sugars of different sugars with the addition of fibers, amino acids, with minerals and vitamins:
1. Sacarose sólida de qualquer tipo de açúcar é diluída com água a um xarope de sacarose de 78,0 Q Brix e aquecida a 80 QC para total dissolução do açúcar, sob agitação no tanque; 1. Solid sucrose of any type of sugar is diluted with water to a sucrose syrup of 78.0 Q Brix and heated to 80 Q C for total dissolution of the sugar, with agitation in the tank;
2. O xarope é invertido QUIMICAMENTE (produtos orgânicos ou não) ou ENZIMATICAMENTE como descrito nos exemplos anteriores; 2. The syrup is inverted CHEMICALLY (organic products or not) or ENZYMATICALLY as described in the previous examples;
3. O xarope é filtrado para retirada de particulados; 4. O xarope filtrado pode ser aditivado com edulcorantes conforme exemplos3. The syrup is filtered to remove particulates; 4. The filtered syrup can be added with sweeteners as examples
1 a 7. 1 to 7.
5. O adoçante pode ser aditivado com fibras, conforme Exemplo 8; 5. The sweetener can be added with fibers, according to Example 8;
6. O adoçante pode ser aditivado com aminoácidos conforme Exemplo 9; 6. The sweetener can be added with amino acids according to Example 9;
7. O adoçante pode ser aditivado com minerais conforme exemplo 10. ;7. The sweetener can be added with minerals according to example 10.;
8. O xarope pode ser aditivado tomando-se como referência a faixa a dose de ingestão diária de vitaminas dos complexos A, B, C, D e E, ácido fólico, riboflavina, tiamina e niacina conforme indicadas a diversas faixas etárias ou grupo de carência segundo Regulamento da ANVISA aprovado pelo Decreto nQ 3.029, de 16 de abril de 1999, c/c o art. 111 , inciso I, alínea “e” do Regimento Interno aprovado pela Portaria nQ 593, de 25 de agosto de 2000, publicada no DOU de 22 de dezembro de 2000, em reunião realizada em 6 de dezembro de 2004. Outras regulamentações nacionais ou internacionais também poderão ser utilizadas como referência. Outras vitaminas, como exemplo vitamina B5 - ácido pantotênico e vitamina K, podem ser aditivados segundo as referências das diversas regulamentações. 8. The syrup can be added by taking as a reference the dose of daily intake of vitamins A, B, C, D and E, folic acid, riboflavin, thiamine and niacin as indicated for different age groups or groups of people. grace period according to ANVISA Regulation approved by Decree No. Q 3,029, of April 16, 1999, with art. 111, item I, item “e” of the Internal Regulations approved by Ordinance No. Q 593, of August 25, 2000, published in the DOU of December 22, 2000, in a meeting held on December 6, 2004. Other national regulations or international agreements can also be used as a Other vitamins, such as vitamin B5 - pantothenic acid and vitamin K, can be added according to the references of the various regulations.
[099] Desta forma, o EXEMPLO 11 refere-se a: [099] Thus, EXAMPLE 11 refers to:
- uso dos açúcares orgânicos ou não: Cristal, VHP, VVHP, DEMERARA, Mascavo, Côco, Beterraba, e outros como base do adoçante; - use of organic sugars or not: Cristal, VHP, VVHP, DEMERARA, Mascavo, Coconut, Beet, and others as a base for the sweetener;
- invertidos QUIMICAMENTE ou ENZIMATICAMENTE em diferentes taxas de inversão (relação sacarose/glicose+frutose: > 90% de inversão); - CHEMICALLY or ENZYMATICALLY inverted at different inversion rates (sucrose / glucose + fructose ratio:> 90% inversion);
- Podendo ser aditivado com edulcorante natural ou sintético; - Can be added with natural or synthetic sweetener;
- Podendo ser enriquecido com FIBRAS; - It can be enriched with FIBERS;
- Podendo ser enriquecido com MINERAIS; - Can be enriched with MINERALS;
- Podendo ser enriquecido com VITAMINAS; - It can be enriched with VITAMINS;
[100] Desta forma, o adoçante pode apresentar a composição conforme exemplo da Tabela 11. [100] In this way, the sweetener can present the composition according to the example in Table 11.
[101] Tabela 11 : Exemplo de composição do adoçante proposto com os aditivos e usando açúcar Demerara invertido (98% inversão) como xarope de base. Exemplo com 100% da Dose recomendada pela Anvisa.
Figure imgf000041_0001
[101] Table 11: Example of the composition of the proposed sweetener with the additives and using inverted Demerara sugar (98% inversion) as base syrup. Example with 100% of the dose recommended by Anvisa.
Figure imgf000041_0001
[102] Exemplo 12 - Produção do adoçante a partir de açúcares dos diversos açúcares com adição de fibras, aminoácidos, aditivado de minerais e vitaminas e substâncias encapsuladas: [102] Example 12 - Production of the sweetener from sugars of the various sugars with the addition of fibers, amino acids, with added minerals and vitamins and encapsulated substances:
1 . Sacarose sólida de qualquer tipo de açúcar é diluída com água a um xarope de sacarose de 78,0 Q Brix e aquecida a 80 QC para total dissolução do açúcar, sob agitação intensa no tanque; 1 . Solid sucrose of any type of sugar is diluted with water to a sucrose syrup of 78.0 Q Brix and heated to 80 Q C for total dissolution of the sugar, under intense agitation in the tank;
2. O xarope é invertido QUIMICAMENTE (produtos orgânicos ou não) ou ENZIMATICAMENTE como descrito nos exemplos anteriores; 2. The syrup is inverted CHEMICALLY (organic products or not) or ENZYMATICALLY as described in the previous examples;
3. O xarope é filtrado para retirada de particulados; 3. The syrup is filtered to remove particulates;
4. O xarope filtrado pode ser aditivado com edulcorantes conforme exemplos4. The filtered syrup can be added with sweeteners as examples
1 a 7. 1 to 7.
5. O adoçante pode ser aditivado com fibras, conforme Exemplo 8; 5. The sweetener can be added with fibers, according to Example 8;
6. O adoçante pode ser aditivado com aminoácidos conforme Exemplo 9; 6. The sweetener can be added with amino acids according to Example 9;
7. O adoçante pode ser aditivado com minerais conforme Exemplo 10; 7. The sweetener can be added with minerals according to Example 10;
8. O adoçante pode ser aditivado com vitaminas conforme Exemplo 11 ; 8. The sweetener can be added with vitamins according to Example 11;
9. O adoçante pode ser aditivado com substâncias encapsuladas, micro encapsuladas ou nano-encapsuladas, por exemplo, melaço de cana, mel de cana, compostos farmacológicos e nutracêuticos, extratos naturais de plantas, mas não limitando-se somente a estes. O processo de encapsulação preserva as propriedades farmacológicas dos produtos e máscara suas possíveis interferências nas propriedades organolépticas do adoçante, no entanto, mantém intactas suas propriedades funcionais. A proporção de aditivação dependerá do tipo de produto a ser aditivado e da concentração das substâncias de interesse, sendo entre 1 ,0 a 10,0% do adoçante. Alguns dos aditivos como, vitaminas, aminoácidos e minerais também poderão ser encapsulados. 9. The sweetener can be added with encapsulated, micro encapsulated or nano-encapsulated substances, for example, cane molasses, cane honey, pharmacological and nutraceutical compounds, natural plant extracts, but not limited to these. The encapsulation process preserves the pharmacological properties of the products and masks their possible interference in the organoleptic properties of the sweetener, however, it keeps its functional properties intact. The proportion of additives will depend on the type of product to be added and the concentration of the substances of interest, being between 1.0 and 10.0% of the sweetener. Some of the additives like vitamins, amino acids and minerals can also be encapsulated.
[103] Desta forma, a reivindicação do EXEMPLO 12 refere-se a: [103] Thus, the claim in EXAMPLE 12 refers to:
- uso dos açúcares orgânicos ou não: Cristal, VHP, VVHP, DEMERARA, Mascavo, Côco, Beterraba, e outros como base do adoçante; - use of organic sugars or not: Cristal, VHP, VVHP, DEMERARA, Mascavo, Coconut, Beet, and others as a base for the sweetener;
- invertidos QUIMICAMENTE ou ENZIMATICAMENTE em diferentes taxas de inversão (relação sacarose/glicose+frutose: > 90% de inversão); - CHEMICALLY or ENZYMATICALLY inverted at different inversion rates (sucrose / glucose + fructose ratio:> 90% inversion);
- Podendo ser aditivado com edulcorante natural ou sintético; - Can be added with natural or synthetic sweetener;
- Podendo ser enriquecido com FIBRAS; - It can be enriched with FIBERS;
- Podendo ser enriquecido com MINERAIS; - Can be enriched with MINERALS;
- Podendo ser enriquecido com VITAMINAS; - It can be enriched with VITAMINS;
- Podendo ser enriquecido com SUBSTÂNCIAS ENCAPSULADAS. [104] Exemplo 13 - Produção do adoçante a partir de açúcares dos diversos açúcares com adição de fibras, aminoácidos, aditivado de minerais, vitaminas, substâncias encapsuladas e extratos naturais de plantas: - It can be enriched with ENCAPSULATED SUBSTANCES. [104] Example 13 - Production of the sweetener from sugars of the various sugars with the addition of fibers, amino acids, additives with minerals, vitamins, encapsulated substances and natural plant extracts:
1. Sacarose sólida de qualquer tipo de açúcar é diluída com água a um xarope de sacarose de 78,0 Q Brix e aquecida a 80 QC para total dissolução do açúcar, sob agitação intensa no tanque; 1. Solid sucrose of any type of sugar is diluted with water to a sucrose syrup of 78.0 Q Brix and heated to 80 Q C for total dissolution of the sugar, under intense agitation in the tank;
2. O xarope é invertido QUIMICAMENTE (produtos orgânicos ou não) ou ENZIMATICAMENTE como descrito nos exemplos anteriores; 2. The syrup is inverted CHEMICALLY (organic products or not) or ENZYMATICALLY as described in the previous examples;
3. O xarope é filtrado para retirada de particulados; 3. The syrup is filtered to remove particulates;
4. O xarope filtrado pode ser aditivado com edulcorantes conforme exemplos de 1 a 7. 4. The filtered syrup can be added with sweeteners according to examples 1 to 7.
5. O adoçante pode ser aditivado com fibras, conforme Exemplo 8; 5. The sweetener can be added with fibers, according to Example 8;
6. O adoçante pode ser aditivado com aminoácidos conforme Exemplo 9; 6. The sweetener can be added with amino acids according to Example 9;
7. O adoçante pode ser aditivado com minerais conforme Exemplo 10; 7. The sweetener can be added with minerals according to Example 10;
8. O adoçante pode ser aditivado com vitaminas conforme Exemplo 11 ; 8. The sweetener can be added with vitamins according to Example 11;
9. O adoçante pode ser aditivado com substâncias encapsuladas conforme Exemplo 12; 9. The sweetener can be added with encapsulated substances according to Example 12;
10. O adoçante pode ser aditivado com extratos de plantas com reconhecidas atividades farmacológicas, como exemplo gengibre, romã, erva cidreira, cravo, canela, menta, erva doce, entre diversos outros que poderão ser utilizados para dar uma atividade funcional ao adoçante, sendo que a proporção de aditivação pode ser de 0,5 % a 10,0 % em peso do adoçante, podendo variar a concentração conforme a aplicação, necessidade comercial ou concentração de princípio ativo da planta no extrato, não se limitando somente a estas. 10. The sweetener can be added with plant extracts with recognized pharmacological activities, such as ginger, pomegranate, lemon balm, cloves, cinnamon, mint, fennel, among several others that can be used to provide a functional activity to the sweetener. that the proportion of additives can be from 0.5% to 10.0% by weight of the sweetener, and the concentration may vary according to the application, commercial need or concentration of the active ingredient of the plant in the extract, not being limited only to these.
[105] Desta forma, a reivindicação do EXEMPLO 13 refere-se a: [105] Thus, the claim in EXAMPLE 13 refers to:
- uso dos açúcares orgânicos ou não: Cristal, VHP, VVHP, DEMERARA, Mascavo, Côco, Beterraba, e outros como base do adoçante; - use of organic sugars or not: Cristal, VHP, VVHP, DEMERARA, Mascavo, Coconut, Beet, and others as a base for the sweetener;
- invertidos QUIMICAMENTE ou ENZIMATICAMENTE em diferentes taxas de inversão (relação sacarose/glicose+frutose: > 90% de inversão); - CHEMICALLY or ENZYMATICALLY inverted at different inversion rates (sucrose / glucose + fructose ratio:> 90% inversion);
- Podendo ser aditivado com edulcorante natural ou sintético; - Podendo ser enriquecido com FIBRAS; - Can be added with natural or synthetic sweetener; - It can be enriched with FIBERS;
- Podendo ser enriquecido com MINERAIS; - Can be enriched with MINERALS;
- Podendo ser enriquecido com VITAMINAS; - It can be enriched with VITAMINS;
- Podendo ser enriquecido com SUBSTÂNCIAS ENCAPSULADAS; - Can be enriched with ENCAPSULATED SUBSTANCES;
- Podendo ser enriquecido com EXTRATOS DE PLANTAS. - It can be enriched with PLANT EXTRACTS.
[106] Exemplo 14 - Produção do adoçante a partir de açúcares dos diversos açúcares com adição de fibras, aminoácidos, aditivado de minerais, vitaminas, substâncias encapsuladas, extratos naturais de plantas e aromas: [106] Example 14 - Production of the sweetener from sugars of different sugars with the addition of fibers, amino acids, with mineral additives, vitamins, encapsulated substances, natural plant extracts and aromas:
1. Sacarose sólida de qualquer tipo de açúcar é diluída com água a um xarope de sacarose de 78,0 Q Brix e aquecida a 80 QC para total dissolução do açúcar, sob agitação intensa no tanque; 1. Solid sucrose of any type of sugar is diluted with water to a sucrose syrup of 78.0 Q Brix and heated to 80 Q C for total dissolution of the sugar, under intense agitation in the tank;
2. O xarope é invertido QUIMICAMENTE (produtos orgânicos ou não) ou ENZIMATICAMENTE como descrito nos exemplos anteriores; 2. The syrup is inverted CHEMICALLY (organic products or not) or ENZYMATICALLY as described in the previous examples;
3. O xarope é filtrado para retirada de particulados; 3. The syrup is filtered to remove particulates;
4. O xarope filtrado pode ser aditivado com edulcorantes conforme exemplos4. The filtered syrup can be added with sweeteners as examples
1 a 7. 1 to 7.
5. O adoçante pode ser aditivado com fibras, conforme Exemplo 8; 5. The sweetener can be added with fibers, according to Example 8;
6. O adoçante pode ser aditivado com aminoácidos conforme Exemplo 9; 6. The sweetener can be added with amino acids according to Example 9;
7. O adoçante pode ser aditivado com minerais conforme Exemplo 10; 7. The sweetener can be added with minerals according to Example 10;
8. O adoçante pode ser aditivado com vitaminas conforme Exemplo 11 ; 8. The sweetener can be added with vitamins according to Example 11;
9. O adoçante pode ser aditivado com substâncias encapsuladas conforme Exemplo 12; 9. The sweetener can be added with encapsulated substances according to Example 12;
10. O adoçante pode ser aditivado com extratos de plantas conforme Exemplo 13: 10. The sweetener can be added with plant extracts according to Example 13:
11. O adoçante pode ser aditivado com aromas naturais, aromas artificiais e aromas idênticos aos naturais, como exemplo, aroma de mel, limão, maracujá, laranja, morango, gengibre, canela, tangerina, entre diversas possibilidades, sendo que a proporção de aditivação pode ser de 0,5 % a 5,0 % em peso do adoçante, podendo variar a concentração conforme a aplicação ou necessidade comercial, não se limitando somente a estas. 11. The sweetener can be added with natural flavors, artificial flavors and flavors identical to natural ones, such as honey, lemon, passion fruit, orange, strawberry, ginger, cinnamon, tangerine, among several possibilities, with the proportion of additives can be from 0.5% to 5.0% by weight of the sweetener, and the concentration may vary depending on the application or commercial need. limiting only to these.
[107] Desta forma, a reivindicação do EXEMPLO 14 refere-se a: [107] Thus, the claim in EXAMPLE 14 refers to:
- uso dos açúcares orgânicos ou não: Cristal, VHP, VVHP, DEMERARA, Mascavo, Côco, Beterraba, e outros como base do adoçante; - use of organic sugars or not: Cristal, VHP, VVHP, DEMERARA, Mascavo, Coconut, Beet, and others as a base for the sweetener;
- invertidos QUIMICAMENTE ou ENZIMATICAMENTE em diferentes taxas de inversão (relação sacarose/glicose+frutose: > 90% de inversão); - CHEMICALLY or ENZYMATICALLY inverted at different inversion rates (sucrose / glucose + fructose ratio:> 90% inversion);
- Podendo ser aditivado com edulcorante natural ou sintético; - Can be added with natural or synthetic sweetener;
- Podendo ser enriquecido com FIBRAS; - It can be enriched with FIBERS;
- Podendo ser enriquecido com MINERAIS; - Can be enriched with MINERALS;
- Podendo ser enriquecido com VITAMINAS; - It can be enriched with VITAMINS;
- Podendo ser enriquecido com SUBSTÂNCIAS- Can be enriched with SUBSTANCES
ENCAPSULADAS; ENCAPSULATED;
- Podendo ser enriquecido com EXTRATOS DE PLANTAS; - Can be enriched with PLANT EXTRACTS;
- Podendo ser aditivado com AROMAS. - Can be added with AROMAS.
[108] Exemplo 15 - Produção do adoçante a partir de açúcares dos diversos açúcares com adição de fibras, aminoácidos, aditivado de minerais, vitaminas, substâncias encapsuladas, extratos naturais de plantas, aromas e substâncias funcionais: [108] Example 15 - Production of the sweetener from sugars of various sugars with the addition of fibers, amino acids, additives with minerals, vitamins, encapsulated substances, natural plant extracts, flavors and functional substances:
1. Sacarose sólida de qualquer tipo de açúcar é diluída com água a um xarope de sacarose de 78,0 Q Brix e aquecida a 80 QC para total dissolução do açúcar, sob agitação intensa no tanque; 1. Solid sucrose of any type of sugar is diluted with water to a sucrose syrup of 78.0 Q Brix and heated to 80 Q C for total dissolution of the sugar, under intense agitation in the tank;
2. O xarope é invertido QUIMICAMENTE (produtos orgânicos ou não) ou ENZIMATICAMENTE como descrito nos exemplos anteriores; 2. The syrup is inverted CHEMICALLY (organic products or not) or ENZYMATICALLY as described in the previous examples;
3. O xarope é filtrado para retirada de particulados; 3. The syrup is filtered to remove particulates;
4. O xarope filtrado pode ser aditivado com edulcorantes conforme exemplos de 1 a 7; 4. The filtered syrup can be added with sweeteners according to examples 1 to 7;
5. O adoçante pode ser aditivado com fibras, conforme Exemplo 8; 5. The sweetener can be added with fibers, according to Example 8;
6. O adoçante pode ser aditivado com aminoácidos conforme Exemplo 9; 6. The sweetener can be added with amino acids according to Example 9;
7. O adoçante pode ser aditivado com minerais conforme Exemplo 10; 7. The sweetener can be added with minerals according to Example 10;
8. O adoçante pode ser aditivado com vitaminas conforme Exemplo 11 ; 8. The sweetener can be added with vitamins as per Example 11;
9. O adoçante pode ser aditivado com substâncias encapsuladas conforme Exemplo 12: 9. The sweetener can be added with encapsulated substances according to Example 12:
10. O adoçante pode ser aditivado com extratos de plantas conforme Exemplo 13; 10. The sweetener can be added with plant extracts according to Example 13;
11. O adoçante pode ser aditivado com aromas conforme Exemplo 14; 11. The sweetener can be added with flavors according to Example 14;
12. O adoçante pode ser aditivado com substâncias funcionais, como exemplo, prébioticos como: inulina, FOS (frutooligossacarídeos), GOS (galactooligossacarídeos), e antioxidantes como: flavonóides da cana, betacarotenos, carotenóides, licopeno, antocianinas, resveratrol, taninos entre outros, mas não só limitadas a estas. A proporção de aditivação dependerá do tipo de produto a ser aditivado e da concentração das substâncias de interesse, sendo entre 1 ,0 a 5,0% do adoçante, mas ajustando ao potencial funcional da substância, bem como aos limites de consumo seguro estabelecido pela ANVISA e/ou outros órgãos reguladores nacionais ou internacionais. 12. The sweetener can be added with functional substances, such as prebiotics such as: inulin, FOS (fructooligosaccharides), GOS (galactooligosaccharides), and antioxidants such as cane flavonoids, beta carotenes, carotenoids, lycopene, anthocyanins, resveratrol, tannins, among others , but not only limited to these. The proportion of additives will depend on the type of product to be added and the concentration of the substances of interest, being between 1.0 and 5.0% of the sweetener, but adjusting to the functional potential of the substance, as well as to the limits of safe consumption established by ANVISA and / or other national or international regulatory bodies.
[109] Desta forma, a reivindicação do EXEMPLO 15 refere-se a: [109] Thus, the claim in EXAMPLE 15 refers to:
- uso dos açúcares orgânicos ou não: Cristal, VHP, VVHP, DEMERARA, Mascavo, Côco, Beterraba, e outros como base do adoçante; - use of organic sugars or not: Cristal, VHP, VVHP, DEMERARA, Mascavo, Coconut, Beet, and others as a base for the sweetener;
- invertidos QUIMICAMENTE ou ENZIMATICAMENTE em diferentes taxas de inversão (relação sacarose/glicose+frutose: > 90% de inversão); - CHEMICALLY or ENZYMATICALLY inverted at different inversion rates (sucrose / glucose + fructose ratio:> 90% inversion);
- Podendo ser aditivado com edulcorante natural ou sintético; - Can be added with natural or synthetic sweetener;
- Podendo ser enriquecido com FIBRAS; - It can be enriched with FIBERS;
- Podendo ser enriquecido com MINERAIS; - Can be enriched with MINERALS;
- Podendo ser enriquecido com VITAMINAS; - It can be enriched with VITAMINS;
- Podendo ser enriquecido com SUBSTÂNCIAS ENCAPSULADAS; - Can be enriched with ENCAPSULATED SUBSTANCES;
- Podendo ser enriquecido com EXTRATOS DE PLANTAS; - Can be enriched with PLANT EXTRACTS;
- Podendo ser aditivado com AROMAS; - Can be added with AROMAS;
- Podendo ser aditivado com SUBSTÂNCIAS FUNCIONAIS. - Can be added with FUNCTIONAL SUBSTANCES.
[110] Exemplo 16 - Produção do adoçante a partir de açúcares dos diversos açúcares com adição de fibras, aminoácidos, aditivado de minerais, vitaminas, substâncias encapsuladas, extratos naturais de plantas, aromas substâncias funcionais e outros açúcares: [110] Example 16 - Production of the sweetener from sugars of different sugars with the addition of fibers, amino acids, with mineral additives, vitamins, encapsulated substances, natural plant extracts, flavorings, functional substances and other sugars:
1. Sacarose sólida de qualquer tipo de açúcar é diluída com água a um xarope de sacarose de 78,0 Q Brix e aquecida a 80 QC para total dissolução do açúcar, sob agitação intensa no tanque; 1. Solid sucrose of any type of sugar is diluted with water to a sucrose syrup of 78.0 Q Brix and heated to 80 Q C for total dissolution of the sugar, under intense agitation in the tank;
2. O xarope é invertido QUIMICAMENTE (produtos orgânicos ou não) ou ENZIMATICAMENTE como descrito nos exemplos anteriores; 2. The syrup is inverted CHEMICALLY (organic products or not) or ENZYMATICALLY as described in the previous examples;
3. O xarope é filtrado para retirada de particulados; 3. The syrup is filtered to remove particulates;
4. O xarope filtrado pode ser aditivado com edulcorantes conforme exemplos de 1 a 7; 4. The filtered syrup can be added with sweeteners according to examples 1 to 7;
5. O adoçante pode ser aditivado com fibras, conforme Exemplo 8; 5. The sweetener can be added with fibers, according to Example 8;
6. O adoçante pode ser aditivado com aminoácidos conforme Exemplo 9; 6. The sweetener can be added with amino acids according to Example 9;
7. O adoçante pode ser aditivado com minerais conforme Exemplo 10; 7. The sweetener can be added with minerals according to Example 10;
8. O adoçante pode ser aditivado com vitaminas conforme Exemplo 11 ; 8. The sweetener can be added with vitamins according to Example 11;
9. O adoçante pode ser aditivado com substâncias encapsuladas conforme Exemplo 12; 9. The sweetener can be added with encapsulated substances according to Example 12;
10. O adoçante pode ser aditivado com extratos de plantas conforme Exemplo 13: 10. The sweetener can be added with plant extracts according to Example 13:
11. O adoçante pode ser aditivado com aromas conforme Exemplo 14; 11. The sweetener can be added with flavors according to Example 14;
13. O adoçante pode ser aditivado com substâncias funcionais conforme Exemplo 15: 13. The sweetener can be added with functional substances according to Example 15:
14. O adoçante pode ser aditivado com outros açúcares tais como exemplos: xilitol, xaropes de high frutose, eritritol, dextrose, maltose, sorbitol, manitol, lactose, xaropes de frutas (exemplo xarope de maçã) entre outros, mas não só restritos a esses. A proporção de aditivação poderá ser entre 0,1 a 50,0 % do adoçante, conforme a proporção ideal e limites de consumo conforme legislação vigente estabelecido por órgãos reguladores nacionais ou internacionais para cada tipo de açúcar. 14. The sweetener can be added with other sugars such as examples: xylitol, high fructose syrups, erythritol, dextrose, maltose, sorbitol, mannitol, lactose, fruit syrups (example apple syrup), among others, but not only restricted to Those. The proportion of additives can be between 0.1 to 50.0% of the sweetener, according to the ideal proportion and consumption limits according to the current legislation established by national or international regulatory bodies for each type of sugar.
[111] Desta forma, a reivindicação do EXEMPLO 16 refere-se a: [111] Thus, the claim in EXAMPLE 16 refers to:
- uso dos açúcares orgânicos ou não: Cristal, VHP, VVHP, DEMERARA, Mascavo, Côco, Beterraba, e outros como base do adoçante; - use of organic sugars or not: Cristal, VHP, VVHP, DEMERARA, Mascavo, Côco, Beet, and others as a base for the sweetener;
- invertidos QUIMICAMENTE ou ENZIMATICAMENTE em diferentes taxas de inversão (relação sacarose/glicose+frutose: > 90% de inversão); - CHEMICALLY or ENZYMATICALLY inverted at different inversion rates (sucrose / glucose + fructose ratio:> 90% inversion);
- Podendo ser aditivado com edulcorante natural ou sintético; - Can be added with natural or synthetic sweetener;
- Podendo ser enriquecido com FIBRAS; - It can be enriched with FIBERS;
- Podendo ser enriquecido com MINERAIS; - Can be enriched with MINERALS;
- Podendo ser enriquecido com VITAMINAS; - It can be enriched with VITAMINS;
- Podendo ser enriquecido com SUBSTÂNCIAS ENCAPSULADAS; - Can be enriched with ENCAPSULATED SUBSTANCES;
- Podendo ser enriquecido com EXTRATOS DE PLANTAS; - Can be enriched with PLANT EXTRACTS;
- Podendo ser aditivado com AROMAS; - Can be added with AROMAS;
- Podendo ser aditivado com SUBSTÂNCIAS FUNCIONAIS; - Can be added with FUNCTIONAL SUBSTANCES;
- Podendo ser aditivado com OUTROS AÇÚCARES. - Can be added with OTHER SUGARS.
[112] Os exemplos acima foram descritos para ilustrar as diferentes formas de produção do adoçante e sua composição final em função dos tipos de inversão, diversos tipos de matéria prima e aditivos, não devendo ser encarados como limitativos desta invenção, sabendo-se que pequenas variações do que fora acima descrito ainda farão parte do escopo desta invenção. [112] The above examples were described to illustrate the different ways of producing the sweetener and its final composition depending on the types of inversion, different types of raw materials and additives, and should not be seen as limiting this invention, knowing that small variations of the above described will still be part of the scope of this invention.
[113] Neste sentido, o escopo da presente invenção também abarca os diferentes usos e aplicações de uma composição de adoçante com propriedades melhoradas, conforme descrita nesta invenção. As aplicações principais, porém, não limitativas, são: Indústria Farmacêutica, Indústria Cosmética, Indústria Alimentícia e Uso de mesa em geral. [113] In this sense, the scope of the present invention also encompasses the different uses and applications of a sweetener composition with improved properties, as described in this invention. The main applications, however, not limiting, are: Pharmaceutical Industry, Cosmetic Industry, Food Industry and Table use in general.

Claims

REIVINDICAÇÕES
1) PROCESSO DE PRODUÇÃO DE ADOÇANTES NUTRITIVOS E BLENDAS caracterizado por produzir composições adoçantes contendo sabor tradicional do açúcar, sem aditivos químicos, com menos calorias nas blendas com edulcorantes, naturais ou sintéticos, contendo aditivos alimentares que permitem a digestibilidade mais lenta dos carboidratos, evitando picos de insulina e melhorando a flora intestinal, e funcionalidades farmacêuticas, contendo as seguintes etapas: a) diluir a sacarose sólida, presente em diferentes tipos de fonte de carboidrato selecionada, com água a um xarope de sacarose de cerca de 76,0 a 80,0 Q Brix; b) aquecer a cerca de 80QC para total dissolução da sacarose, sob agitação no tanque; c) o xarope é então resfriado a cerca de 55,0 a 60,0 QC e o pH acertado a 2,0 a 5,0 com uso de ácidos ou barrilhas; d) nos casos de inversão enzimática, o pH é acertado a 4,5 e adiciona-se a enzima invertase, GMO-free ou comercial, ao xarope e a reação é mantida a 55QC até o tempo necessário para atingir a inversão de até cerca de 98,0% da sacarose em partes equimolares de glicose e frutose nas condições descritas; além disso, no caso da inversão enzimática o controle de pH e temperatura permitem evitar a produção de furfural; e) opcionalmente, o xarope pode ser aditivado com edulcorantes naturais ou sintéticos, fibras naturais, vitaminas, minerais, aminoácidos, aromas, extratos vegetais, substâncias funcionais e outros açúcares e, desta forma, mantendo o potencial farmacológico devido ao uso de açúcares escuros que apresentam na sua composição natural os compostos farmacologicamente ativos. 1) NUTRITIVE AND BLENDING PROCESSES PRODUCTION PROCESS characterized by producing sweetening compositions containing traditional sugar flavor, without chemical additives, with less calories in blends with sweeteners, natural or synthetic, containing food additives that allow the slower digestibility of carbohydrates, avoiding insulin spikes and improving intestinal flora, and pharmaceutical functionalities, containing the following steps: a) dilute the solid sucrose, present in different types of selected carbohydrate source, with water to a sucrose syrup of about 76.0 to 80 , 0 Q Brix; b) heat to about 80 Q C to complete dissolution of the sucrose, stirring in the tank; c) the syrup is then cooled to about 55.0 to 60.0 Q C and the pH adjusted to 2.0 to 5.0 with the use of acids or shanks; d) in the case of enzymatic inversion, the pH is adjusted to 4.5 and the enzyme invertase, GMO-free or commercial, is added to the syrup and the reaction is maintained at 55 Q C until the time necessary to reach the inversion of up to about 98.0% of sucrose in equimolar parts of glucose and fructose under the conditions described; in addition, in the case of enzymatic inversion, the pH and temperature control allow to avoid the production of furfural; e) optionally, the syrup can be added with natural or synthetic sweeteners, natural fibers, vitamins, minerals, amino acids, flavors, plant extracts, functional substances and other sugars and, thus, maintaining the pharmacological potential due to the use of dark sugars that present in their natural composition the pharmacologically active compounds.
2) PROCESSO, de acordo com a reivindicação 1, caracterizado pelas fontes de sacarose para a produção do adoçante serem preferencialmente: açúcar cristal, Demerara, VHP, VVHP, mascavo, de beterraba, de côco, orgânicos ou não, sólidos ou líquidos. 2) PROCESS, according to claim 1, characterized by the sources of sucrose for the production of the sweetener being preferably: crystal sugar, Demerara, VHP, VVHP, brown, beet, coconut, organic or not, solid or liquid.
3) PROCESSO, de acordo com a reivindicação 1, caracterizado pelos ácidos utilizados para inversão química da sacarose serem preferencialmente ácido cítrico, ácido fosfórico, ácidos da lista positiva de orgânicos. 4) PROCESSO, de acordo com a reivindicação 1 , caracterizado pelo processo possuir opcionalmente uma etapa de filtração do xarope para retirada dos particulados. 3) PROCESS, according to claim 1, characterized in that the acids used for chemical inversion of sucrose are preferably citric acid, phosphoric acid, acids from the positive organic list. 4) PROCESS, according to claim 1, characterized by the process optionally having a syrup filtration step for removing the particulates.
5) PROCESSO, de acordo com a reivindicação 1 , caracterizado pelas blendas de adoçante serem produzidas a partir da adição de edulcorantes ao xarope da etapa “e”, podendo ser Estevia, sacarina, ciclamato, aspartame, acelsulfame, alitame/neotame, sucralose e taumatina, entre outros, em diferentes concentrações de forma a atingir um dulçor igual ou maior ao da sacarose não invertida e uma menor quantidade relativa de caloria. 5) PROCESS, according to claim 1, characterized by the sweetener blends being produced from the addition of sweeteners to the syrup of step “e”, which can be Estevia, saccharin, cyclamate, aspartame, acelsulfame, alitame / neotame, sucralose and thaumatin, among others, in different concentrations in order to achieve a sweetness equal to or greater than that of uninverted sucrose and a smaller relative amount of calorie.
6) PROCESSO, de acordo com as reivindicações 1 e 5, caracterizado pela blenda de adoçante preferencialmente utilizar um xarope 78Q Brix (90 a 98% de inversão) com Estevia em uma concentração, por exemplo de 2,6 g por cada 1 kg de xarope; ainda, por opcionalmente conter um xarope 78Q Brix (90 a 98% de inversão) com Estevia em uma concentração, por exemplo de 5,2 g por cada 1 kg de xarope; bem como pela blenda de adoçante poder ainda apresentar adições preferenciais de outros edulcorantes por kg de xarope, como exemplo: 3,3g/kg de sacarina; 5g/kg de aspartame; 5g/kg de acelsulfame; 0,5g/kg neotame; 1 ,65g/kg de sucralose e 0,33g/kg de taumatina, não se limitando somente a estas concentrações. 6) PROCESS, according to claims 1 and 5, characterized by the sweetener blend preferably using a 78 Q Brix syrup (90 to 98% inversion) with Estevia in a concentration, for example 2.6 g for each 1 kg syrup; also, for optionally containing a 78 Q Brix syrup (90 to 98% inversion) with Estevia in a concentration, for example of 5.2 g for each 1 kg of syrup; as well as the sweetener blend can still present preferential additions of other sweeteners per kg of syrup, as an example: 3.3g / kg of saccharin; 5g / kg of aspartame; 5g / kg of acelsulfame; 0.5g / kg neotame; 1, 65g / kg of sucralose and 0.33g / kg of thaumatin, not limited only to these concentrations.
7) PROCESSO, de acordo com as reivindicações 1 a 6, caracterizado pelas fibras adicionadas de 1 a 20% aos adoçantes ou blendas de adoçante, serem solúveis, insolúveis e suas misturas de 1 a 99% de cada, serem orgânicas ou não, e serem selecionadas preferencialmente dentre: fibras vegetais como as de milho, mandiocas, tapiocas; fibras como inulina, polidextroses, maltodextrinas; fibras constituídas de polímeros de carboidratos, com três ou mais unidades monoméricas; fibras de lignina, fibras polissacarídicas não- amido; oligassacarídeos; carboidratos análogos, como amido resistentes e maltodextrinas resistentes; compostos associados a fibra alimentar, como compostos fenólicos, proteína de parede celular, oxalatos, fitatos, ceras, cutina, suberina; fibras de origem animal, como quitina, quitosana, colágeno, condroitina. 7) PROCESS, according to claims 1 to 6, characterized in that the fibers added from 1 to 20% to the sweeteners or blends of sweetener, are soluble, insoluble and their mixtures from 1 to 99% of each, are organic or not, and preferentially selected from: vegetable fibers such as corn, cassava, tapioca; fibers such as inulin, polydextroses, maltodextrins; fibers made of carbohydrate polymers, with three or more monomer units; lignin fibers, non-starch polysaccharide fibers; oligosaccharides; analogous carbohydrates, such as resistant starch and resistant maltodextrins; compounds associated with dietary fiber, such as phenolic compounds, cell wall protein, oxalates, phytates, waxes, cutin, suberin; fibers of animal origin, such as chitin, chitosan, collagen, chondroitin.
8) PROCESSO, de acordo com as reivindicações 1 a 7, caracterizado pelos aminoácidos da etapa “e” poder ser selecionado dentre diversos tipos de aminoácidos de cadeia ramificada, tais como: ácido glutâmico, ácido aspártico, glutamina, histidina, glicina, treonina, alanina, arginina, prolina, tirosina, valina, metionina, cisteina, leucina, fenilalanina, isoleucina, triptofano, ornitina e/ou lisina; ainda, pelos minerais da etapa “e” poderem ser selecionados dentre: Zinco, Cálcio, Fósforo, Ferro, Magnésio, cobre, selênio, manganês e/ou fósforo, mas não limitado somente a estes; assim como, pelas vitaminas da etapa “e” poderem ser selecionadas dentre: vitaminas dos complexos A, B, C, D e E, ácido fólico, riboflavina, tiamina, niacina e vitamina K, mas não limitado somente a estes. 8) PROCESS, according to claims 1 to 7, characterized by the amino acids of step “e” being able to be selected among several types of branched chain amino acids, such as: glutamic acid, aspartic acid, glutamine, histidine, glycine, threonine, alanine, arginine, proline, tyrosine, valine, methionine, cysteine, leucine, phenylalanine, isoleucine, tryptophan, ornithine and / or lysine; still, by the minerals of step “e” can be selected from: Zinc, Calcium, Phosphorus, Iron, Magnesium, copper, selenium, manganese and / or phosphorus, but not limited to these only; as well as, because the vitamins of step “e” can be selected from: vitamins of complexes A, B, C, D and E, folic acid, riboflavin, thiamine, niacin and vitamin K, but not limited only to these.
9) PROCESSO, de acordo com as reivindicações 1 a 8, caracterizado pelas substâncias aditivadas ao adoçante ou as blendas de adoçantes poderem estar encapsuladas, microencapsuladas ou ainda nanoencapsuladas; ainda, pelas substâncias serem opcionalmente o melaço de cana, o mel de cana, compostos farmacológicos, compostos nutracêuticos, extratos naturais de plantas, vitaminas, aminoácidos e minerais. 9) PROCESS, according to claims 1 to 8, characterized by the substances added to the sweetener or the blends of sweeteners may be encapsulated, microencapsulated or even nanoencapsulated; yet, because the substances are optionally sugarcane molasses, cane honey, pharmacological compounds, nutraceutical compounds, natural plant extracts, vitamins, amino acids and minerals.
10) PROCESSO, de acordo com as reivindicações 1 a 9, caracterizado pelos extratos vegetais serem preferencialmente extratos de plantas com reconhecidas atividades farmacológicas, tais como: gengibre, romã, erva cidreira, canela, cravo, menta, erva doce, entre diversos outros que poderão ser utilizados para dar uma atividade funcional ao adoçante, mas não limitado somente a estes; ainda, pelos aromas adicionados na etapa “e” poderem ser naturais, artificiais e aromas idênticos aos naturais, tais como os exemplos: aroma de mel, limão, maracujá, tangerina, gengibre, laranja, morango, entre outros, mas não limitado somente a estes. 10) PROCESS, according to claims 1 to 9, characterized in that the plant extracts are preferably plant extracts with recognized pharmacological activities, such as: ginger, pomegranate, lemongrass, cinnamon, cloves, mint, fennel, among several others that they can be used to give the sweetener a functional activity, but not limited to them only; also, because the aromas added in step “e” may be natural, artificial and aromas identical to natural ones, such as the examples: aroma of honey, lemon, passion fruit, tangerine, ginger, orange, strawberry, among others, but not limited only to these.
11) PROCESSO, de acordo com as reivindicações 1 a 10, caracterizado pelas substâncias funcionais adicionadas na etapa “e” poderem ser prebióticos como: inulina, FOS (frutooligossacarídeos), GOS (galactooligossacarídeos), e antioxidantes como flavonóides, betacarotenos, carotenóides, licopeno, antocianinas, resveratrol, taninos, entre outros; ainda, pelos açúcares adicionais da etapa “e” poderem ser opcionalmente: xilitol, xaropes de high frutose, eritritol, dextrose, maltose, sorbitol, manitol, lactose, xaropes de frutas (exemplo xarope de maçã), entre outros. 11) PROCESS, according to claims 1 to 10, characterized by the functional substances added in step “e” can be prebiotics such as: inulin, FOS (fructooligosaccharides), GOS (galactooligosaccharides), and antioxidants such as flavonoids, betacarotenes, carotenoids, lycopene , anthocyanins, resveratrol, tannins, among others; also, due to the additional sugars from step “e” they can be optionally: xylitol, high fructose syrups, erythritol, dextrose, maltose, sorbitol, mannitol, lactose, fruit syrups (example apple syrup), among others.
12) COMPOSIÇÃO DE ADOÇANTES NUTRITIVOS E BLENDAS, caracterizada por ser produzida pelo processo das reivindicações 1 a 11 , obtendo uma composição com qualidade uniforme, preservando o sabor do açúcar, reduzindo a quantidade de calorias, contendo pelo menos uma quantidade determinada de uma fonte de sacarose, invertida química ou enzimaticamente, e uma porcentagem de edulcorantes ou blendas de edulcorantes, naturais ou sintéticos, aumentando o poder de dulçor da composição, ao mesmo tempo que diminui o seu teor calórico, assim como quantidades de acordo com a recomendação diária de fibras, aminoácidos minerais, vitaminas, substâncias encapsuladas, extratos vegetais, aromas, substancias funcionais e/ou outros açúcares; ainda, por poder variar a concentração de edulcorantes para mais ou para menos, para se obter um aumento ou diminuição da relação entre dulçor e teor de caloria da composição adoçante final; assim como, 12) COMPOSITION OF NUTRITIVE AND BLENDING SWEETS, characterized by being produced by the process of claims 1 to 11, obtaining a composition with uniform quality, preserving the flavor of the sugar, reducing the amount of calories, containing at least a certain amount of a sucrose source, inverted chemically or enzymatically, and a percentage of sweeteners or blends of sweeteners, natural or synthetic, increasing the sweetening power of the composition at the same time that decreases its caloric content, as well as amounts according to the daily recommendation of fibers, mineral amino acids, vitamins, encapsulated substances, plant extracts, flavors, functional substances and / or other sugars; still, because it can vary the concentration of sweeteners more or less, to obtain an increase or decrease in the relationship between sweetness and calorie content of the final sweetener composition; as,
13) COMPOSIÇÃO, de acordo com as reivindicação 12, caracterizada pela relação dulçor e teor calórico poder ser vantajosamente obtida nas seguintes razões: 151 Kcal com Xarope 78 Q Brix (98% de inversão) e 2,6 g de Estevia por cada kg de xarope obtendo um dulçor duas vezes maior que a de 100% de xarope de sacarose; ou, ainda por também poder ser obtida quando se adiciona 3,3g de sacarina; 33g de ciclamato; 5g de aspartame; 5g de acelsulfame; 0,5 de neotame; 1,65 de sucralose; ou 0,33g de taumatina. 13) COMPOSITION, according to claim 12, characterized by the sweetness and caloric content ratio that can be advantageously obtained in the following reasons: 151 Kcal with 78 Q Brix Syrup (98% inversion) and 2.6 g of Estevia for each kg of syrup obtaining a sweetness twice that of 100% sucrose syrup; or, also because it can also be obtained when adding 3.3 g of saccharin; 33g cyclamate; 5g of aspartame; 5g of acelsulfame; 0.5 neotame; 1.65 sucralose; or 0.33g of thaumatin.
14) COMPOSIÇÃO, de acordo com a reivindicação 12, caracterizada pela quantidade de fibra poder ser de 0,5 a 20% de fibras solúveis e/ou insolúveis, orgânicas ou não, sendo preferencialmente selecionadas entre: fibras vegetais como as de milho, mandiocas, tapiocas; fibras como inulina, polidextroses, maltodextrinas; fibras constituídas de polímeros de carboidratos, com três ou mais unidades monoméricas; fibras de lignina, fibras polissacarídicas não-amido; oligassacarídeos; carboidratos análogos, como amido resistentes e maltodextrinas resistentes; compostos associados a fibra alimentar, como compostos fenólicos, proteína de parede celular, oxalatos, fitatos, ceras, cutina, suberina; fibras de origem animal, como quitina, quitosana, colágeno, condroitina. 14) COMPOSITION, according to claim 12, characterized in that the amount of fiber can be from 0.5 to 20% of soluble and / or insoluble fibers, organic or not, being preferably selected among: vegetable fibers such as corn, cassava , tapioca; fibers such as inulin, polydextroses, maltodextrins; fibers made of carbohydrate polymers, with three or more monomer units; lignin fibers, non-starch polysaccharide fibers; oligosaccharides; analogous carbohydrates, such as resistant starch and resistant maltodextrins; compounds associated with dietary fiber, such as phenolic compounds, cell wall protein, oxalates, phytates, waxes, cutin, suberin; fibers of animal origin, such as chitin, chitosan, collagen, chondroitin.
15) COMPOSIÇÃO, de acordo com as reivindicações 12 a 14, caracterizada pelos aminoácidos estarem em concentrações indicadas para ingestão diária e poderem ser selecionados dentre diversos tipos de aminoácidos de cadeia ramificada, tais como: ácido glutâmico, ácido aspártico, glutamina, histidina, glicina, treonina, alanina, arginina, prolina, tirosina, valina, metionina, cisteina, leucina, fenilalanina, isoleucina, triptofano, ornitina e/ou lisina; ainda, pelos minerais estarem em concentrações indicadas para ingestão diária e poderem ser selecionados dentre: Zinco, Cálcio, Fósforo, Ferro, Magnésio, cobre, selênio, manganês e/ou fósforo. 15) COMPOSITION, according to claims 12 to 14, characterized in that the amino acids are in concentrations indicated for daily intake and can be selected from several types of branched chain amino acids, such as: glutamic acid, aspartic acid, glutamine, histidine, glycine , threonine, alanine, arginine, proline, tyrosine, valine, methionine, cysteine, leucine, phenylalanine, isoleucine, tryptophan, ornithine and / or lysine; also, because the minerals are in concentrations indicated for daily intake and can be selected from: Zinc, Calcium, Phosphorus, Iron, Magnesium, copper, selenium, manganese and / or phosphorus.
16) COMPOSIÇÃO, de acordo com as reivindicações 12 a 15, caracterizada pelas vitaminas estarem em concentrações indicadas para ingestão diária e poderem ser selecionadas dentre: vitaminas dos complexos A, B, C, D e E, ácido fólico, riboflavina, tiamina, niacina e vitamina K; ainda, pelas substâncias aditivadas ao adoçante ou as blendas de adoçantes poderem estar encapsuladas, microencapsuladas ou ainda nanoencapsuladas; e, ainda, pelas substâncias serem opcionalmente o melaço de cana, o mel de cana, compostos farmacológicos, compostos nutracêuticos, extratos naturais de plantas, vitaminas, aminoácidos e minerais. 16) COMPOSITION, according to claims 12 to 15, characterized by the vitamins being in concentrations indicated for daily intake and can be selected from: vitamins of complexes A, B, C, D and E, folic acid, riboflavin, thiamine, niacin and vitamin K; still, due to the substances added to the sweetener or the blends of sweeteners may be encapsulated, microencapsulated or even nanoencapsulated; and, also, because the substances are optionally sugarcane molasses, cane honey, pharmacological compounds, nutraceutical compounds, natural plant extracts, vitamins, amino acids and minerals.
17) COMPOSIÇÃO, de acordo com as reivindicações 12 a 16, caracterizada pelos extratos vegetais poderem ser preferencialmente de 0,5 % a 10,0 % em peso do adoçante e serem preferencialmente extratos de plantas com reconhecidas atividades farmacológicas, tais como: gengibre, romã, erva cidreira, cravo, menta, erva doce, entre diversos outros que poderão ser utilizados para dar uma atividade funcional ao adoçante; ainda, pelos aromas serem adicionados na proporção de 0,5 % a 5,0 % em peso do adoçante e poderem ser naturais, artificiais e aromas idênticos aos naturais, tais como: aroma de mel, limão, gengibre, canela, maracujá, laranja, morango, entre outros. 17) COMPOSITION, according to claims 12 to 16, characterized in that the plant extracts can preferably be from 0.5% to 10.0% by weight of the sweetener and are preferably plant extracts with recognized pharmacological activities, such as: ginger, pomegranate, lemongrass, cloves, mint, fennel, among many others that can be used to give the sweetener a functional activity; also, because the aromas are added in the proportion of 0.5% to 5.0% by weight of the sweetener and can be natural, artificial and aromas identical to the natural ones, such as: aroma of honey, lemon, ginger, cinnamon, passion fruit, orange , strawberry, among others.
18) COMPOSIÇÃO, de acordo com as reivindicações 12 a 17, caracterizada pela quantidade das substâncias funcionais depender do tipo de produto a ser aditivado e da concentração das substâncias de interesse, sendo de forma geral preferencialmente incluído entre 1 ,0 a 5,0% do adoçante final, ajustando ao potencial funcional da substância, bem como aos limites de consumo seguro estabelecido, e poderem ser prebióticos como: inulina, FOS (frutooligossacarídeos), GOS (galactooligossacarídeos), e antioxidantes como: Phytolin (flavonóides da cana), betacarotenos, carotenóides, licopeno, antocianinas, resveratrol, taninos, entre outros; e, ainda, pelos açúcares serem adicionados em uma proporção de 1 a 50% do adoçante final e poderem ser opcionalmente: xilitol, xaropes de high frutose, dextrose, maltose, eritritol, sorbitol, manitol, lactose, xaropes de frutas (exemplo xarope de maçã), entre outros. 18) COMPOSITION, according to claims 12 to 17, characterized in that the quantity of the functional substances depends on the type of product to be added and on the concentration of the substances of interest, being, in general, preferably between 1.0 and 5.0% of the final sweetener, adjusting to the functional potential of the substance, as well as the limits for safe consumption established, and may be prebiotics such as: inulin, FOS (fructooligosaccharides), GOS (galactooligosaccharides), and antioxidants such as: Phytolin (sugarcane flavonoids), beta-carotenes , carotenoids, lycopene, anthocyanins, resveratrol, tannins, among others; and, also, because the sugars are added in a proportion of 1 to 50% of the final sweetener and can be optionally: xylitol, high fructose syrups, dextrose, maltose, erythritol, sorbitol, mannitol, lactose, fruit syrups (example apple syrup), among others.
19) COMPOSIÇÃO, de acordo com as reivindicações acima, caracterizada por uma composição ser a base de açúcar demerara e possuir a seguinte composição média em 100g com 90% de inversão da sacarose e 78Q Brix: a) 22,0 ± 1% de água; b) 35,0 ± 0,5% de frutose; c) 35,0 ± 0,5% de Glicose; d) 7,0 ± 0,5% de Sacarose; e) 0,5 - 20,0% fibras totais; f) de 20 mg a 39 mg de aminoácidos; g) 9,3 mg/1 OOg de sódio; h) Até 7,0 mg/1 OOg de zinco; i) 1 ,4 - 4,9 mg/1 OOg de Potássio; j) Até 260,0 mg/1 OOg de Magnésio; k) Até 1000,0 mg/1 OOg de cálcio; 19) COMPOSITION, according to the above claims, characterized in that a composition is based on demerara sugar and has the following average composition in 100g with 90% sucrose inversion and 78 Q Brix: a) 22.0 ± 1% of Water; b) 35.0 ± 0.5% fructose; c) 35.0 ± 0.5% Glucose; d) 7.0 ± 0.5% of sucrose; e) 0.5 - 20.0% total fibers; f) from 20 mg to 39 mg of amino acids; g) 9.3 mg / 1 OOg of sodium; h) Up to 7.0 mg / 1 OOg of zinc; i) 1, 4 - 4.9 mg / 1 OOg of Potassium; j) Up to 260.0 mg / 1 OOg of Magnesium; k) Up to 1000.0 mg / 1 OOg of calcium;
L) Até 14,0 mg/1 OOg de ferro; m) Até 700,0 mg/1 OOg de fósforo; n) Até 0,6 mg/1 OOg de vitamina A; o) Até 1 ,2 mg/1 OOg de Tiamina; p) Até 1 ,3 mg/1 OOg de riboflavina; q) Até 16,0 mg/1 OOg de niacina; r) Até 1 ,3 mg/1 OOg de piridoxina; s) Até 0,4 mg/1 OOg de ácido fólico t) Até 45,0 mg/1 OOg de vitamina C; u) Até 0,005 mg/1 OOg de vitamina D; e/ou v) Até 10,0 mg/1 OOg de vitamina E. L) Up to 14.0 mg / 1 OOg of iron; m) Up to 700.0 mg / 1 OOg of phosphorus; n) Up to 0.6 mg / 1 OOg of vitamin A; o) Up to 1.2 mg / 1 OOg of Thiamine; p) Up to 1.3 mg / 1 OOg of riboflavin; q) Up to 16.0 mg / 1 OOg of niacin; r) Up to 1.3 mg / 1 OOg of pyridoxine; s) Up to 0.4 mg / 1 OOg of folic acid t) Up to 45.0 mg / 1 OOg of vitamin C; u) Up to 0.005 mg / 1 OOg of vitamin D; and / or v) Up to 10.0 mg / 1 OOg of vitamin E.
20) USO DO ADOÇANTE NUTRITIVO E BLENDAS, caracterizado por aplicar as composições com propriedades melhoradas das reivindicações 12 a 20 e produzidas pelos processos das reivindicações 1 a 19 nas indústrias farmacêutica, cosmética, alimentícia e no uso de mesa em geral, mas não limitado somente a estas 20) USE OF NUTRITIVE SWEETENERS AND BLENDS, characterized by applying the compositions with improved properties of claims 12 to 20 and produced by the processes of claims 1 to 19 in the pharmaceutical, cosmetic, food and table use in general, but not limited only to these
PCT/BR2020/050411 2019-10-17 2020-10-14 Composition, production method and use of nutritive sweeteners and blends WO2021072521A1 (en)

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