WO2021067968A1 - Interventions sur le microbiome - Google Patents

Interventions sur le microbiome Download PDF

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Publication number
WO2021067968A1
WO2021067968A1 PCT/US2020/054316 US2020054316W WO2021067968A1 WO 2021067968 A1 WO2021067968 A1 WO 2021067968A1 US 2020054316 W US2020054316 W US 2020054316W WO 2021067968 A1 WO2021067968 A1 WO 2021067968A1
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WO
WIPO (PCT)
Prior art keywords
composition
companion animal
microbiome
day
bacterial
Prior art date
Application number
PCT/US2020/054316
Other languages
English (en)
Inventor
Zoe Marshall-Jones
Richard HAYDOCK
Ciaran O'FLYNN
Luis Molina
Yann Queau
Hirotaka IGARASHI
Original Assignee
Mars, Incorporated
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Filing date
Publication date
Application filed by Mars, Incorporated filed Critical Mars, Incorporated
Priority to US17/766,103 priority Critical patent/US20220362324A1/en
Priority to EP20803681.4A priority patent/EP4037493A1/fr
Priority to CN202080070142.9A priority patent/CN114786494A/zh
Priority to EP24152595.5A priority patent/EP4368730A2/fr
Publication of WO2021067968A1 publication Critical patent/WO2021067968A1/fr

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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/40—Feeding-stuffs specially adapted for particular animals for carnivorous animals, e.g. cats or dogs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/82—Theaceae (Tea family), e.g. camellia
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • A23K10/37—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms from waste material
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/105—Aliphatic or alicyclic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/111—Aromatic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/163—Sugars; Polysaccharides
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/179—Colouring agents, e.g. pigmenting or dyeing agents
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/20—Inorganic substances, e.g. oligoelements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/01—Hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/717—Celluloses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • A23K10/18—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/174—Vitamins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/20—Inorganic substances, e.g. oligoelements
    • A23K20/30—Oligoelements
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P60/00—Technologies relating to agriculture, livestock or agroalimentary industries
    • Y02P60/80—Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
    • Y02P60/87—Re-use of by-products of food processing for fodder production

Abstract

La présente invention concerne des compositions comprenant une gamme d'ingrédients appropriés pour une utilisation dans l'adaptation et/ou le traitement d'un animal de compagnie tel qu'un canidé (par exemple un chien) ou un félin (par exemple un chat) et leurs microbiomes, des outils de surveillance et des méthodes de diagnostic pour déterminer l'état de santé d'un animal de compagnie et son microbiome.
PCT/US2020/054316 2019-10-04 2020-10-05 Interventions sur le microbiome WO2021067968A1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
US17/766,103 US20220362324A1 (en) 2019-10-04 2020-10-05 Microbiome interventions
EP20803681.4A EP4037493A1 (fr) 2019-10-04 2020-10-05 Interventions sur le microbiome
CN202080070142.9A CN114786494A (zh) 2019-10-04 2020-10-05 微生物组干预
EP24152595.5A EP4368730A2 (fr) 2019-10-04 2020-10-05 Interventions sur le microbiome

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB201914385A GB201914385D0 (en) 2019-10-04 2019-10-04 Microbiome Interventions
GB1914385.8 2019-10-04

Publications (1)

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WO2021067968A1 true WO2021067968A1 (fr) 2021-04-08

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PCT/US2020/054316 WO2021067968A1 (fr) 2019-10-04 2020-10-05 Interventions sur le microbiome

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US (1) US20220362324A1 (fr)
EP (2) EP4368730A2 (fr)
CN (1) CN114786494A (fr)
GB (1) GB201914385D0 (fr)
WO (1) WO2021067968A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210375430A1 (en) * 2020-05-29 2021-12-02 Kpn Innovations, Llc. Methods, systems, and devices for generating a refreshment instruction set based on individual preferences

Citations (7)

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Publication number Priority date Publication date Assignee Title
US20050281910A1 (en) * 1999-09-22 2005-12-22 Eduardo Schiffrin Method for increasing pet activity
US8722112B2 (en) * 2005-07-14 2014-05-13 Hill's Pet Nutrition, Inc. Method for prolonging the life of animals
WO2017117091A1 (fr) * 2015-12-30 2017-07-06 Hill's Pet Nutrition, Inc. Compositions alimentaires pour animal domestique
WO2018006080A1 (fr) 2016-07-01 2018-01-04 Evolve Biosystems Inc. Méthode pour faciliter la maturation du système immunitaire de mammifères
US20180064140A1 (en) * 2016-09-02 2018-03-08 Nestec Sa Compositions and methods for modulating gastrointestinal microflora in a canine
US20200014292A1 (en) 2017-02-17 2020-01-09 General Electric Technology Gmbh Improvements in or relating to gate drivers for gas tubes
WO2020150712A1 (fr) 2019-01-18 2020-07-23 Mars, Incorporated Outils de surveillance et méthodes de diagnostic

Patent Citations (7)

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Publication number Priority date Publication date Assignee Title
US20050281910A1 (en) * 1999-09-22 2005-12-22 Eduardo Schiffrin Method for increasing pet activity
US8722112B2 (en) * 2005-07-14 2014-05-13 Hill's Pet Nutrition, Inc. Method for prolonging the life of animals
WO2017117091A1 (fr) * 2015-12-30 2017-07-06 Hill's Pet Nutrition, Inc. Compositions alimentaires pour animal domestique
WO2018006080A1 (fr) 2016-07-01 2018-01-04 Evolve Biosystems Inc. Méthode pour faciliter la maturation du système immunitaire de mammifères
US20180064140A1 (en) * 2016-09-02 2018-03-08 Nestec Sa Compositions and methods for modulating gastrointestinal microflora in a canine
US20200014292A1 (en) 2017-02-17 2020-01-09 General Electric Technology Gmbh Improvements in or relating to gate drivers for gas tubes
WO2020150712A1 (fr) 2019-01-18 2020-07-23 Mars, Incorporated Outils de surveillance et méthodes de diagnostic

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ANNA SALAS-MANI ET AL: "Fecal microbiota composition changes after a BW loss diet in Beagle dogs", JOURNAL OF ANIMAL SCIENCE, vol. 96, no. 8, 28 July 2018 (2018-07-28), US, pages 3102 - 3111, XP055698927, ISSN: 0021-8812, DOI: 10.1093/jas/sky193 *
BIAGI G ET AL: "Influence of some potential prebiotics and fibre-rich foodstuffs on composition and activity of canine intestinal microbiota", ANIMAL FEED SCIENCE AND TECHNOLOGY, ELSEVIER, AMSTERDAM, NL, vol. 159, no. 1-2, 20 July 2010 (2010-07-20), pages 50 - 58, XP027118431, ISSN: 0377-8401, [retrieved on 20100714] *
CARLO PINNA ET AL: "The Utilisation of Prebiotics and Synbiotics in Dogs", ITALIAN JOURNAL OF ANIMAL SCIENCE, vol. 13, no. 1, 1 January 2014 (2014-01-01), pages 3107, XP055764685, DOI: 10.4081/ijas.2014.3107 *
DATABASE GNPD [online] MINTEL; 14 March 2019 (2019-03-14), ANONYMOUS: "Chicken + Vegetable Vitalized Nutrition Dog Food", XP055764797, Database accession no. 6403589 *
DATABASE GNPD [online] MINTEL; 19 June 2019 (2019-06-19), ANONYMOUS: "Dog Food for Adult to Senior Maltese 10 Months and Up", XP055764765, Database accession no. 6643663 *
DATABASE GNPD [online] MINTEL; 20 March 2019 (2019-03-20), ANONYMOUS: "Lamb Meal & Brown Rice Recipe Balanced Natural Nutrition Food for Adult Dogs", XP055764792, Database accession no. 6402839 *
DATABASE GNPD [online] MINTEL; 20 September 2019 (2019-09-20), ANONYMOUS: "Chicken, Sweet Potato & Pumpkin Grain Free Adult Dog Food", XP055764788, Database accession no. 6880667 *
DATABASE GNPD [online] MINTEL; 21 August 2019 (2019-08-21), ANONYMOUS: "Wishbone Chicken & Green Lentil Recipe Dog Food", XP055764790, Database accession no. 6795561 *
DATABASE GNPD [online] MINTEL; 22 September 2017 (2017-09-22), ANONYMOUS: "Super Premium Food For Senior Dogs", XP055764762, Database accession no. 5123787 *
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DATABASE GNPD [online] MINTEL; 7 May 2019 (2019-05-07), ANONYMOUS: "Fit & Firm 7+ Senior Dog Food", XP055764814, Database accession no. 6520579 *
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JAN S. SUCHODOLSKI ET AL: "The Fecal Microbiome in Dogs with Acute Diarrhea and Idiopathic Inflammatory Bowel Disease", PLOS ONE, vol. 7, no. 12, 26 December 2012 (2012-12-26), pages e51907, XP055221020, DOI: 10.1371/journal.pone.0051907 *
KRISTY N KUZMUK ET AL: "Nutrient Metabolism Diet and Age Affect Intestinal Morphology and Large Bowel Fermentative End-Product Concentrations in Senior and Young Adult Dogs 1,2", 4 May 2005 (2005-05-04), pages 1 - 6, XP055418537, Retrieved from the Internet <URL:http://jn.nutrition.org/content/135/8/1940.full.pdf> [retrieved on 20171024] *

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GB201914385D0 (en) 2019-11-20
EP4037493A1 (fr) 2022-08-10
CN114786494A (zh) 2022-07-22
EP4368730A2 (fr) 2024-05-15
US20220362324A1 (en) 2022-11-17

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