WO2021056645A1 - 弹性成像方法、系统及计算机可读存储介质 - Google Patents
弹性成像方法、系统及计算机可读存储介质 Download PDFInfo
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- WO2021056645A1 WO2021056645A1 PCT/CN2019/112507 CN2019112507W WO2021056645A1 WO 2021056645 A1 WO2021056645 A1 WO 2021056645A1 CN 2019112507 W CN2019112507 W CN 2019112507W WO 2021056645 A1 WO2021056645 A1 WO 2021056645A1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/08—Detecting organic movements or changes, e.g. tumours, cysts, swellings
- A61B8/0833—Detecting organic movements or changes, e.g. tumours, cysts, swellings involving detecting or locating foreign bodies or organic structures
- A61B8/085—Detecting organic movements or changes, e.g. tumours, cysts, swellings involving detecting or locating foreign bodies or organic structures for locating body or organic structures, e.g. tumours, calculi, blood vessels, nodules
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/44—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
- A61B8/4444—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device related to the probe
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/46—Ultrasonic, sonic or infrasonic diagnostic devices with special arrangements for interfacing with the operator or the patient
- A61B8/467—Ultrasonic, sonic or infrasonic diagnostic devices with special arrangements for interfacing with the operator or the patient characterised by special input means
- A61B8/469—Ultrasonic, sonic or infrasonic diagnostic devices with special arrangements for interfacing with the operator or the patient characterised by special input means for selection of a region of interest
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/48—Diagnostic techniques
- A61B8/485—Diagnostic techniques involving measuring strain or elastic properties
Definitions
- This application relates to the field of medical technology, and in particular to an elastography method, system, and computer-readable storage medium.
- Instantaneous elastography uses the vibration of the probe to generate a shear wave that is transmitted to the tested tissue, and transmits ultrasound to detect the internal displacement of the tissue, thereby calculating and displaying the elastic parameters of the tested tissue.
- a motion parameter image of tissue displacement or strain is generally provided.
- the embodiments of the present application provide an elasticity imaging method, system, and computer-readable storage medium, which can improve the comprehensibility of elasticity test results.
- an elastography method is provided, which is applied to an elastography system.
- the elastography system includes a probe, a transmitting circuit connected to the probe, a receiving circuit connected to the probe, and a receiving circuit connected to the receiving device.
- a beam combiner of a circuit, a processor connected to the beam combiner, and a display screen for displaying image information transmitted by the processor, the elastic imaging method includes:
- the processor is controlled to display the main propagation path map and the elasticity information of the tested tissue in the display screen.
- an elastography method which includes:
- an elastography method which includes:
- an elastography method including:
- an elastography system including:
- the probe is used to transmit the first ultrasonic wave to the tested tissue to track the shear wave propagating in the tested tissue, and the probe is also used to receive the first ultrasonic echo returned by the tested tissue to obtain the first ultrasonic echo -Ultrasonic echo data;
- the display screen is connected to the processor, and the processor is used to display the main propagation path map and the elasticity information of the tested tissue in the display screen.
- a computer-readable storage medium is provided, and the computer-readable storage medium is used to store a computer program for electronic data exchange, wherein the computer program causes a computer to execute the method described in any of the foregoing embodiments. Some or all of the steps described.
- the elastic imaging method, system, and computer-readable storage medium of the embodiments of the present application obtain the main propagation path of the shear wave according to the motion parameter or the motion parameter image, and display the main propagation path.
- the motion parameter image caused by the probe can be reduced. Vibration will cause various after-waves, reflected waves and other interference information to cause medical staff to be unable to more accurately explain the insufficiency of the meaning displayed by the motion parameter image, and it is also helpful to improve the intelligibility of the elasticity test results.
- FIG. 1 is a schematic diagram of the hardware structure of an elasticity imaging system in an embodiment of the present application.
- Fig. 2 is a flow chart of the steps of an elastography method in an embodiment of the present application.
- Fig. 3 is a schematic diagram of a motion parameter image in an embodiment of the present application.
- Fig. 4 is a block diagram of the hardware structure of the probe in an embodiment of the present application.
- FIG. 5 is a schematic diagram of multiple band-shaped regions in a motion parameter image in an embodiment of the present application.
- FIG. 6 is a schematic diagram of binarization of the main propagation path graph in an embodiment of the present application.
- FIG. 7 is a schematic diagram of non-binarization of the main propagation path graph in an embodiment of the present application.
- FIG. 8 is a schematic diagram of the main propagation path in an embodiment of the present application.
- Fig. 9 is a flow chart of the steps of an elastography method in an embodiment of the present application.
- Fig. 10 is a schematic block diagram of an elastography system in an embodiment of the present application.
- Fig. 11 is a schematic diagram of a motion parameter image in an embodiment of the present application.
- Fig. 12 is a schematic diagram of a motion parameter image in another embodiment of the present application.
- Fig. 13 is a schematic diagram of a motion parameter image in still another embodiment of the present application.
- the elastography system 10 may include a probe 100, a transmitting circuit 102 connected to the probe 100, a receiving circuit 104 connected to the probe 100, a beam combiner 106, a processor 110, and a display 112.
- the receiving circuit 104, the beam combiner 106, The processor 110 and the display 112 can be electrically connected in sequence.
- the elastography system 10 can obtain the motion parameter or motion parameter image of the tested tissue, and obtain the main propagation path of the shear wave in the tested tissue according to the motion parameter or motion parameter image, and can display it on the display screen. The main propagation path is displayed in 112.
- the main propagation path can be a single path that can accurately represent the propagation position of shear waves at different depths, various residual waves, reflected waves and other interference information can be excluded when acquiring the main propagation path. In this way, medical staff intuitively pass the inclusion of the main propagation path.
- the motion parameter image of the propagation path or the main propagation path diagram for diagnosis is beneficial to improve the intelligibility of the elasticity test results.
- the beam combiner 106 and the processor 110 may be implemented by a dedicated circuit or a commercially available chip.
- FIG. 2 shows a flow chart of the steps of the elastography method in an embodiment of the present application.
- the elastography method includes the following steps:
- Step 200 Obtain a motion parameter image of the tissue under test.
- the transmitting circuit 102 transmits the first transmitting sequence to the probe 100 to control the probe 100 to transmit the first ultrasonic wave to the tested tissue, where the first ultrasonic wave is used to track the shear wave propagating in the tested tissue.
- the probe 100 can receive the first ultrasonic echo with the information of the test object reflected from the tested tissue.
- the probe 100 can convert this ultrasonic echo into an electrical signal.
- the receiving circuit 104 receives the electric signal converted and generated by the probe 100 to obtain the first ultrasonic echo data, and sends the first ultrasonic echo data to the beam combiner 106.
- the beam combiner 106 performs beam combining processing such as focus delay, weighting, and channel summation on the ultrasonic echo data, and then sends the ultrasonic echo data after beam processing to the processor 110, which is based on the first ultrasonic echo
- the data acquires the motion parameter or motion parameter image of the tissue under test, and is used to display it on the display screen 112.
- FIG. 3 shows a schematic diagram of a motion parameter image in an embodiment of the application.
- the motion parameter image includes horizontal time attributes and vertical depth attributes.
- the processor 110 obtains the motion parameters of the tested tissue at different times and at different depths caused by the propagation of the shear wave in the tested tissue based on the first ultrasonic echo data, where the motion parameters may include displacement and velocity. Or strain.
- the processor 110 compares and analyzes the first ultrasonic echo data obtained at different times (such as a cross-correlation algorithm), and can calculate the displacement of the tested tissue at different times, and the first echo from different depths of the tested tissue
- the data is separately calculated for displacement, and finally a displacement matrix corresponding to different depths and different times can be obtained.
- each data represents the displacement information of the measured tissue at a certain depth at a certain time.
- the strain matrix can be obtained accordingly.
- each data represents the strain information of a certain depth of the tissue under test at a certain moment.
- the processor 110 may determine the motion parameter image 150 of the tissue under test based on the motion parameters of the shear wave at different times and at different depths.
- the probe 100 includes an array-type acoustic head 130, a vibrator 132, and a sensor 134 located between the array-type acoustic head 130 and the vibrator 132.
- the transmitting circuit 102 may transmit an excitation sequence to the probe 100 to control the vibrator 132 of the probe 100 to vibrate and generate shear waves in the tissue under test.
- the array acoustic head 130 of the probe 100 tracks the shear wave propagating in the tested tissue according to the first emission timing.
- the array acoustic head 130 includes a preset number of array elements, and the arrangement of the array elements of the array acoustic head 130 is a linear arrangement or a fan arrangement.
- the sensor 132 is used to sense the force with which the probe 100 presses the tested tissue. In an embodiment, the probe 100 may not include the sensor 134.
- the medical staff may need to detect a target location range of the tested tissue. Therefore, the medical staff needs to select the region of interest corresponding to the target location range in the basic image, where the basic image includes the B image , One or more of C images.
- the transmitting circuit 102 transmits a second transmission sequence to the probe 100 to control the probe 100 to transmit the second ultrasonic wave to the tissue under test. After the probe 100 transmits the second ultrasonic wave to the tested tissue, after a certain delay, the probe 100 can receive the second ultrasonic echo with the information of the test object reflected from the tested tissue. The probe 100 can convert this ultrasonic echo into an electrical signal.
- the receiving circuit 104 receives the electric signal converted and generated by the probe 100 to obtain the second ultrasonic echo data, and sends the second ultrasonic echo data to the beam combiner 106.
- the beam combiner 106 performs beam combining processing such as focus delay, weighting, and channel summation on the ultrasound echo data, and then sends the ultrasound echo data after beam processing to the processor 110, and the processor 110 performs imaging according to the user's requirements.
- Different modes of the signal are processed differently to obtain tissue image data of different modes, and then processed by logarithmic compression, dynamic range adjustment, digital scan transformation, etc., to form ultrasound tissue images of different modes, which are used for display on the display 112.
- different modes of ultrasound tissue images may include M images, B images, C images, etc., or other types of two-dimensional ultrasound tissue images or three-dimensional ultrasound tissue images.
- the first ultrasonic wave and the second ultrasonic wave emitted by the probe 100 can be the same, that is, the processor 110 can simultaneously obtain the parameter information corresponding to the shear wave and generate the instantaneous wave after processing the ultrasonic echo received by the probe 100.
- Ultrasound and first ultrasonic waves, or interspersed emission of first ultrasound and second ultrasound (for example, after emitting the first ultrasound, the second ultrasound is emitted, and then the first ultrasound is emitted, so that the interspersed and repeated cycles are performed), so, the processor 110 can obtain the parameter information corresponding to the shear wave by processing the first ultrasonic echo corresponding to the first ultrasonic wave received by the probe 100, generate the instantaneous elastic image, and receive the second ultrasonic wave corresponding to the second ultrasonic wave by the probe 100 After ultrasonic echo processing, different modes of ultrasonic tissue images can be generated.
- the medical staff can determine the region of interest in the basic image; the processor 110 can obtain the target position range corresponding to the region of interest in the first ultrasound echo data, and base it on The first ultrasonic echo data within the target position range determines the elastic information of the tested tissue, such as the shear wave propagation velocity, shear modulus, and Young's modulus within the target position range of the tested tissue.
- Step 202 Determine the main propagation path of the shear wave propagating in the tested tissue in the motion parameter image, and obtain a main propagation path map.
- the processor 110 determines the target area corresponding to the motion parameters in the preset range at each depth in the motion parameter image 150, and may determine the target time range of the target area in the time attribute, where the target time range Including several target moments.
- the processor 110 determines a band-shaped area based on consecutive target areas in the motion parameter image 150. Due to the influence of various residual waves, reflected waves and other interference information caused by the vibration of the probe, the processor 110 may obtain one or more band regions when acquiring the band regions based on the continuous target regions in the motion parameter image 150.
- the motion parameter image 150 may include a first strip-shaped area S1, a second strip-shaped area S2, and a third strip-shaped area S3.
- the motion parameter image 150 includes several pixels. Because the pixel value of each pixel in the motion parameter image 150 corresponds to the size of the motion parameter at the depth corresponding to the pixel.
- the processor 110 may perform grayscale processing on the motion parameter image 150.
- the processor 110 may determine the maximum extreme value range or the minimum extreme value range as the preset range, where the maximum extreme value range may be a to 255, and the target area may be the motion parameter image 150 (as shown in FIG. 3 ); the minimum extreme value range can be 0 to b, and the target area can be the black belt area in the motion parameter image 150 (as shown in FIG. 3).
- the target area may also be the area between the bright band area and the black band area in the motion parameter image 150 (as shown in FIG. 3).
- the processor 110 can use this pixel and a preset number of other pixels separated from the pixel as the target area corresponding to the set depth; or, when the pixel value of a pixel is in the maximum extreme value range and is in line with the The pixel values of other pixels with a preset number of pixel intervals are all within the minimum extreme value range.
- the processor 110 may use the pixel and the preset number of other pixels with the pixel point as the set depth.
- the corresponding target area below.
- the processor 110 determines the depth
- the target area corresponding to V1 includes the target area AB and the target area EF, where the target area AB is a set of pixels in the motion parameter image 150 whose motion parameters are within the minimum extreme value range at a depth of V1 (such as line segments).
- the target time range corresponding to the target area AB is from t1 to the target time t2;
- the target area EF is a set of pixels in the motion parameter image 150 whose motion parameters are within the minimum extreme value range at a depth of V1 (such as line segment EF ), the target time range corresponding to the target area EF is t5 to t6 target time; and when the depth of the motion parameter image 150 is V1, the target area AB and other areas outside the target area EF do not meet the minimum extreme value range.
- the processor 110 may also determine the target area corresponding to the depth V2, including the target area CD, where the target area CD is the set of pixels in the motion parameter image 150 whose motion parameters are within the minimum extreme value range at the depth V2 (Such as the line segment CD), the target time range corresponding to the target area CD is t3 to t4 target time, and the other areas outside the target area CD in the motion parameter image 150 do not meet the minimum extreme value range when the depth is V2.
- the processor 110 determines one or more band-shaped regions based on consecutive target regions in the motion parameter image 150. Since the shear wave is continuous in the tested tissue, the target area at different depths is continuous. In this way, the processor 110 has a strip-shaped area composed of consecutive target areas in the motion parameter image 150. For example, the processor 110 determines the first strip-shaped area S1, the second strip-shaped area S2, and the second strip-shaped area S2 in the motion parameter image 150. The third band S3.
- the processor 110 determines that there are multiple band-shaped regions in the motion parameter image 150, it means that there is interference information in the motion parameter image 150. Therefore, the processor 110 can determine the target band-shaped region that meets the preset condition among the plurality of band-shaped regions. Is the main propagation path of the shear wave.
- the processor 110 can obtain the reference time corresponding to the end of the vibration of the probe 100, and determine the target time in the one or more band-shaped regions
- the band-shaped area composed of the target area later than the reference time is the main propagation path. For example, if the reference time corresponding to the end of the vibration of the probe 100 is t0, since the target time corresponding to the third strip-shaped area S3 is earlier than the reference time t0, the processor 110 determines the first strip-shaped area S1 and the first The target time in the two belt-shaped areas S2 is later than the reference time t0 in the target area.
- the main propagation path of the motion parameter image 150 is a band-shaped area.
- the processor 110 may determine that the first belt-shaped area S1 and the second belt-shaped area S2 have the largest length or the largest area as the main propagation path of the shear wave, wherein each belt-shaped area includes the first A hypotenuse and a second hypotenuse, the length of the band-shaped area can be expressed as the length of the first hypotenuse or the second hypotenuse, or the longer of the first and second hypotenuses; the area of the band-shaped area It can be expressed as the first hypotenuse, the second hypotenuse, the difference between the projections of the first end of the first hypotenuse and the first end of the second hypotenuse on the time axis, and the second end of the first hypotenuse and the second oblique The area of the quadrilateral enclosed by the difference between the projections of the second end of the edge on the time axis, and the second end of the first hypotenuse and the second oblique The area of the quadr
- the processor 110 may determine that the first belt-shaped area is the main propagation of the shear wave. path.
- the processor 110 may directly determine that the strip-shaped region with the largest length or the largest area among the one or more strip-shaped regions is the main propagation path of the shear wave. For example, in the first belt-shaped area S1, the second belt-shaped area S2, and the third belt-shaped area S3, the first belt-shaped area S1 has the largest length and the largest area. Therefore, the processor 110 may determine the first belt-shaped area. The area is the main propagation path of the shear wave.
- the processor 110 may also no longer need to determine the band. Attribute information of the length or area of the shape area.
- the region of interest when determining the region of interest of the tested tissue, the region of interest may be located at a preset depth.
- the processor 110 may determine that the target band-shaped region located at the preset depth is the main propagation path .
- the preset depth is the depth V1
- the processor 110 may determine that the target area below the line segment AB in the first belt-shaped area S1 satisfies the condition, the second belt-shaped area S2 satisfies the condition, and the line segment in the third belt-shaped area S3
- the target area below EF satisfies the condition, and the processor 110 may also obtain three band-shaped areas.
- the main propagation path of the motion parameter image 150 is a band-shaped area.
- the processor 110 may determine that the target area below the line segment AB in the first strip-shaped area S1, the second strip-shaped area S2, and the target area below the line segment EF in the third strip-shaped area S3 have the largest length or the largest area.
- the strip area is the main propagation path of the shear wave.
- the processor 110 may determine that the target area below the line segment AB in the first strip area S1 is the main propagation path of the shear wave.
- the processor 110 when it is determined that there are multiple band regions in the target band region located at the preset depth, the processor 110 also determines the target band region based on the reference time corresponding to the end of the vibration of the probe 100. For example, since the target time corresponding to the second strip-shaped area S2 is earlier than the reference time t0, the processor 110 may determine the target area below the line segment AB in the first strip-shaped area S1 and the target area in the third strip-shaped area S3. The target area below the line segment EF satisfies the condition, and then the processor 110 may determine that the target area below the line segment AB in the first strip-shaped area S1 and the target area below the line segment EF in the third strip-shaped area S3 have the largest length or the largest area.
- the belt-shaped area of is the main propagation path of the shear wave, that is, the processor 110 may determine that the target area below the line segment AB in the first belt-shaped area S1 is the main propagation path of the shear wave.
- the main propagation path diagram is a diagram that characterizes the actual main propagation path of the shear wave in the tested tissue. It is based on the propagation of the shear wave in the tested tissue at different times. And the motion parameters or motion parameter maps at different depths.
- the band-shaped area on the right side that extends to the upper right is the reflected wave of the shear wave.
- the band-shaped area on the right side of the dashed line in Figure 12 is the aftermath of the shear wave.
- the right side of the dashed line in Figure 13 The band-shaped and oblong area of is the reflected wave and after wave of the shear wave. It can be seen that the obtained motion parameter or motion parameter map contains interference information such as various aftermaths and reflected waves of the shear wave, which will affect the doctor's view and the detection of elastic parameters.
- the main propagation path diagram representing the actual main propagation path of the shear wave in the tested tissue is obtained based on the motion parameter or the motion parameter map, and the main propagation path diagram can be Excluding interference information such as residual waves and reflected waves in the motion parameter or motion parameter graph, so as to more accurately reflect the actual main propagation path of the shear wave in the tested tissue, which is convenient for doctors to view.
- Step 204 Display the motion parameter image including the main propagation path.
- the processor 110 When the processor 110 obtains the main propagation path of the shear wave in the motion parameter image 150, the processor 110 displays the main propagation path diagram 160 (shown in FIG. 6) through the display 112, where the main propagation path diagram also includes The motion parameter image of the main propagation path. Since the main propagation path diagram includes the display area corresponding to the main propagation path and other areas outside the main propagation path, the main propagation path diagram has eliminated the influence of interference information, which improves the comprehensibility of the elastic test results and also It can make the medical staff intuitively diagnose according to the main propagation path diagram.
- the processor 110 may also determine the elasticity information of the tissue under test based on the aforementioned first ultrasound echo data or the aforementioned motion parameter image or the aforementioned main propagation path map.
- the elastic information of the tested tissue can be parameters such as the propagation velocity of the shear wave, the Young's modulus of the tested tissue, and the shear modulus of the tested tissue.
- FIG. 6 shows a schematic diagram of binarization of the main propagation path graph in an embodiment of the present application.
- the processor 110 may perform binarization processing on the motion parameter image 150, so that the main propagation path in the motion parameter image 150 is displayed in the first color, which is one of the main propagation paths.
- the outer area is displayed in the second color, which is better for medical staff to identify.
- the processor 110 may set the target band-shaped area corresponding to the main propagation path in the motion parameter image 150 to the first color (such as white), and set the area outside the target band-shaped area corresponding to the main propagation path as The second color (such as black).
- the main propagation path map obtained can distinguish the display area of the main propagation path and the main propagation path. Other areas. For example, when the preset range is the minimum extreme value range, the processor 110 sets the pixels in the motion parameter image 150 whose pixel values are greater than the preset threshold as the first color, that is, sets the colors of other areas outside the main propagation path to Black; the processor 110 also sets the pixel points in the motion parameter image whose pixel value is not greater than the preset threshold value as the second color, that is, sets the color of the display area of the main propagation path to white. In this way, after the processor 110 performs binarization processing on the motion parameter image 150, the main propagation path map 160 can be directly obtained.
- FIG. 7 is a schematic diagram of non-binarization of the main propagation path graph in an embodiment of the application.
- the motion parameters such as strain information or displacement information
- the processor 110 can display the main propagation path graph 160 non-binarized.
- the processor 110 may set the pixel value of the pixel at each depth in the target strip region corresponding to the main propagation path to a third color having a corresponding motion parameter, wherein the third color corresponding to different motion parameters is different ;
- the area outside the target band-shaped area corresponding to the main propagation path can be set to the fourth color.
- FIG. 8 shows a schematic diagram of the main propagation path in another embodiment of the present application.
- the processor 110 may also display some specific depth points on the main propagation path for a simple display. For example, the processor 110 can display only the circle in FIG. 8 (not including the two oblique sides of the first belt-shaped area S1) in the display 112 for simple display.
- the processor 110 may calculate the elastic parameters of the tested tissue, including but not limited to shear wave velocity, Young's modulus, and shear modulus. Wait. As shown in FIG. 5, the processor 110 can fit the straight line shown by the dashed line in the figure based on the main propagation path, where the slope of the straight line shown by the dashed line can be used to represent the shear wave velocity; the processor 110 can be willing to the shear wave Speed to calculate the Young’s modulus of the tested structure, etc. In an embodiment, the processor 110 also includes multiple measurement statistical results of the aforementioned parameters, etc., such as the median, quartile, and ratio of the quartile to the median of Young’s modulus obtained from 10 measurements. Wait.
- the processor 110 may control the display screen 112 to display the basic image, the region of interest located in the basic image, the Young's modulus of the tested tissue, and/or the main propagation path diagram for medical personnel to diagnose.
- the above-mentioned elastic imaging method obtains the main propagation path of the shear wave in the motion parameter image and displays the motion parameter image including the main propagation path. In this way, it can reduce various after waves and reflected waves caused by the vibration of the probe in the motion parameter image.
- the influence of the interference information causes the medical staff to be unable to more accurately explain the insufficiency of the meaning displayed by the motion parameter image, and it is also helpful to improve the intelligibility of the elasticity test results.
- an elastography method may include the following steps:
- the first ultrasonic echo Receiving the ultrasonic echo of the first ultrasonic wave returned by the tested tissue (herein referred to as the first ultrasonic echo) to obtain the first ultrasonic echo data;
- the motion parameters may include the displacement of the tested tissue , Speed or strain;
- the elastic information of the tested tissue can also be determined according to the aforementioned first ultrasonic echo data or the motion parameter or the main propagation path diagram, and the elastic information of the tested tissue can also be displayed to the user.
- the flexibility information may be displayed simultaneously with the main propagation path diagram, or may be displayed non-simultaneously with the main propagation path diagram.
- the motion parameters that meet the preset conditions can be determined from these motion parameters (herein referred to as "target motion parameters"), and the main propagation path of the shear wave can be obtained according to the depth and time corresponding to the target motion parameters.
- the preset conditions can be various suitable conditions, which can be set according to actual needs. For example, the preset conditions can be greater than a preset threshold, within a preset range, and so on.
- the confidence level of the elasticity information of the tested tissue can also be determined according to the obtained main propagation path.
- one or more confidence parameters corresponding to the main propagation path may be determined according to the main propagation path, and the confidence of the elasticity information of the tissue under test may be determined according to the one or more confidence parameters.
- the confidence parameter may include the linearity parameter of the main propagation path, the error parameter when calculating the shear wave propagation velocity by the straight line fitting of the main propagation path, the length parameter of the main propagation path, One or more of the area parameters of the main propagation path and so on.
- the basic image of the tested tissue can also be acquired, and the basic image of the tested tissue can be displayed simultaneously with the aforementioned main propagation path diagram and elasticity information of the tested tissue.
- the basic image may be one or more of the B image, C image or other mode images of the tissue under test.
- the basic image can be obtained in real time by the ultrasound imaging system, that is, the ultrasound probe is used to transmit ultrasound to the tested tissue and receive the ultrasound echo to obtain the ultrasound echo signal, and obtain the basic image of the tested tissue according to the ultrasound echo signal; or The basic image of the tissue under test read in advance from other equipment and stored.
- the confidence level of the elasticity information of the tested tissue can also be displayed.
- FIG. 9 shows a flowchart of the steps of the elastic imaging method in another embodiment of the present application.
- the elastography method includes the following steps:
- Step 300 Obtain a motion parameter image of the tissue under test.
- Step 300 in this embodiment is similar to step 200 in the foregoing embodiment. For details, please refer to step 200 described above.
- Step 302 Determine the main propagation path of the shear wave propagating in the tested tissue in the motion parameter image.
- Step 302 in this embodiment is similar to step 202 in the foregoing embodiment.
- Step 302 please refer to the foregoing step 202.
- Step 304 Display the motion parameter image including the main propagation path.
- Step 304 in this embodiment is similar to step 204 in the foregoing embodiment.
- Step 204 please refer to step 204 described above.
- Step 306 Control the processor to determine the confidence level of the elasticity information of the tested tissue.
- the processor 110 may calculate the elastic information of the tested tissue according to the main propagation path, and further, the reliability of the main propagation path affects the elastic information of the tested tissue. Therefore, the processor 150 may determine the confidence level of the elasticity information of the tested tissue based on the one or more confidence parameters corresponding to the main propagation path, and based on the one or more confidence parameters, where the confidence parameter includes the main propagation path.
- the processor 150 may determine the confidence level of the elasticity information of the tested tissue based on the one or more confidence parameters corresponding to the main propagation path, and based on the one or more confidence parameters, where the confidence parameter includes the main propagation path.
- the Young's modulus value of the liver tissue is calculated mainly by judging the average propagation velocity of the shear wave in the liver tissue, thereby reflecting the degree of liver fibrosis.
- the larger the Young's modulus the harder the liver tissue and the higher the degree of liver fibrosis.
- liver fibrosis is mainly a diffuse disease, the shear wave propagation speed is uniform, the main propagation path is a straight path, and the slope of the straight path corresponds to the speed of the shear wave one by one.
- the main propagation path is too short (for example, it only propagates to a depth of 50mm), it means that the shear wave energy is weak or the attenuation is large, resulting in insufficient penetration; if the main propagation path is curved or not too straight If the main propagation path is not calculated at all, it means that the calculated slope or the propagation velocity of the shear wave or the Young’s modulus of the organization may be inaccurate; if the main propagation path is not calculated at all, it means that the The data quality of this inspection is too poor to obtain effective results.
- the confidence level may be the linearity parameter of the above-mentioned main propagation path (such as determining the linearity of the main propagation path path). The better the linearity of the main propagation path, the higher the reliability of the processor 110 in determining the elasticity information of the tested tissue; Alternatively, the confidence level may be the error corresponding to the processor 110 fitting a straight line to the main propagation path (such as fitting by the least squares method) and calculating the slope of the fitted straight line. When the error is smaller, the processor 110 determines The higher the reliability of the elasticity information of the tested tissue; or, the confidence level may be the length parameter that the processor 110 can determine the main propagation path.
- the processor 110 determines the elasticity information of the tested tissue.
- the higher the reliability of the; or, the confidence level may be the area parameter of the main propagation path that the processor 110 can determine. The larger the area, the higher the reliability of the processor 110 in determining the elasticity information of the tested tissue.
- the confidence level may be a comprehensive scoring parameter obtained by the processor 110 based on the weighted balance of the multiple confidence parameters described above.
- Step 308 Control to output prompt information corresponding to the confidence level of the elasticity information of the tested tissue.
- the processor 110 may display the confidence level of the elasticity information of the tested tissue based on the above-mentioned one or more confidence parameters on the display screen 112, and the value corresponding to each confidence parameter has a corresponding confidence level, such as the confidence level. In this way, the medical staff can determine the reliability of calculating the elasticity information of the tested tissue according to the displayed confidence.
- the processor 110 may display the basic image, the confidence level, and the main propagation path map of the tested tissue on the display screen 112.
- the processor 110 may also display the region of interest determined by the medical staff on the basic image, and may display the Young's modulus of the tested tissue calculated according to the calculated shear wave velocity.
- the above-mentioned elasticity imaging method determines the confidence level of the elasticity information of the tested tissue through the main propagation path graph, and the medical staff can conveniently determine the reliability and comprehensibility of the elasticity information of the tested tissue according to the displayed confidence.
- FIG. 10 shows a schematic block diagram of an elastic imaging system 80 in another embodiment of the present application.
- the elastic imaging system 80 can apply the above-mentioned embodiments.
- the elastography system 80 provided by the present application will be described below.
- the elastography system 80 may include a processor 800, a storage device 802, a probe 100, a control circuit 804, and a display screen 112, as well as being stored in the storage device 802 and A computer program (instruction) that can be run on the processor 800, and the elastic imaging system 80 may also include other hardware parts, such as communication devices, keys, and keyboards, which are not repeated here.
- the processor 800 can exchange data with the probe 100, the control circuit 904, the storage device 802, and the display 112 through the signal line 808.
- the processor 800 may be a central processing unit (Central Processing Unit, CPU), other general-purpose processors, digital signal processors (Digital Signal Processor, DSP), application specific integrated circuits (Application Specific Integrated Circuit, ASIC), Ready-made programmable gate array (Field-Programmable Gate Array, FPGA) or other programmable logic devices, discrete gates or transistor logic devices, discrete hardware components, etc.
- the general-purpose processor can be a microprocessor or the processor can also be any conventional processor, etc.
- the processor is the control center of the elastography system 80, and various interfaces and lines are used to connect the entire elastography system 80. Various parts.
- the processor 800 can be used to implement all the functions of the aforementioned image processing module 110, and can also integrate the functions of components such as the beam combiner 106.
- the processor 800 can generate a first emission sequence to control the probe 100 to generate the first ultrasound; the processor 800 can generate a second emission sequence to control the probe 100 to generate the second ultrasound; the processor 800 can generate an excitation sequence and control After the probe 100 vibrates, a shear wave is generated in the tested tissue.
- the control circuit 804 may include the functions of the transmitting circuit 102, the receiving circuit 104, and/or the beam combiner 106 in the foregoing embodiment, and the functions of the specific components may refer to the foregoing embodiment.
- the control circuit 804 can generate the first emission sequence to control the probe 100 to generate the first ultrasonic wave; the control circuit 804 can generate the second emission sequence to control the probe 100 to generate the second ultrasonic wave; the control circuit 804 can generate the excitation sequence and control After the probe 100 vibrates, a shear wave is generated in the tested tissue.
- the storage device 802 may be used to store the computer program and/or module.
- the processor 800 runs or executes the computer program and/or module stored in the storage device 802 and calls the computer program and/or module stored in the storage device 802.
- the data to achieve the various functions of the above-mentioned elastography method.
- the storage device 802 may store ultrasonic echo data, and the processor 800 can determine the main propagation path of the shear wave according to the ultrasonic echo data.
- the storage device 802 may mainly include a storage program area and a storage data area, wherein , The storage program area can store the operating system, at least one application program required by the function, and so on.
- the storage device 802 may include a high-speed random access storage device, and may also include a non-volatile storage device, such as a hard disk, a memory, a plug-in hard disk, a smart media card (SMC), and a secure digital (Secure Digital). , SD) card, flash memory card (Flash Card), at least one magnetic disk storage device, flash memory device, or other volatile solid-state storage device.
- the display 112 can display a user interface (UI), a graphical user interface (GUI), and the display 112 can include a liquid crystal display (LCD), a thin film transistor LCD (TFT-LCD), an organic light emitting diode (OLED) touch display, and a flexible At least one of a touch display, a three-dimensional (3D) touch display, and the like.
- UI user interface
- GUI graphical user interface
- LCD liquid crystal display
- TFT-LCD thin film transistor LCD
- OLED organic light emitting diode
- the processor 800 reads the executable program code stored in the storage device 802 to run a program corresponding to the executable program code, so as to execute the elastic imaging method in any of the foregoing embodiments.
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Abstract
Description
Claims (39)
- 一种弹性成像方法,应用于弹性成像系统,其特征在于,所述弹性成像系统包括探头、连接于所述探头的发射电路、连接于所述探头的接收电路、连接于所述接收电路的波束合成器、连接于所述波束合成器的处理器和显示所述处理器所传输的图像信息的显示屏,所述弹性成像方法包括:控制所述探头在接收到所述发射电路的第一发射时序时向受测组织发射第一超声波,以跟踪在所述受测组织内传播的剪切波;控制所述探头接收所述受测组织返回的第一超声回波,并将所述第一超声回波转换为电信号后传输至所述接收电路;控制所述波束合成器对所述接收电路传输来的电信号进行波束合成,获得第一超声回波数据;控制所述处理器基于所述第一超声回波数据获得所述受测组织的运动参数图像;控制所述处理器确定所述运动参数图像中所述剪切波的主传播路径,获得主传播路径图,其中所述主传播路径图表征所述剪切波在所述受测组织中的主传播路径;控制所述处理器根据所述第一超声回波数据或者所述运动参数图像或者所述主传播路径图确定所述受测组织的弹性信息;控制所述处理器将所述主传播路径图和所述受测组织的弹性信息显示于所述显示屏内。
- 如权利要求1所述的弹性成像方法,其特征在于,所述控制所述处理器基于所述第一超声回波数据获取所述受测组织的运动参数图像,包括:控制所述处理器基于所述第一超声回波数据获得所述剪切波在所述受测组织中的传播引起的所述受测组织在不同时刻及不同深度下的运动参数,其中,所述运动参数包括位移、速度或者应变;控制所述处理器基于所述剪切波在不同时刻及不同深度下的运动参数确定所述受测组织的运动参数图像。
- 如权利要求1或者2所述的弹性成像方法,其特征在于,所述控制所述处理器确定所述运动参数图像中所述剪切波的主传播路径包括:控制所述处理器确定每一深度下位于预设范围的运动参数所对应的目标区域;控制所述处理器基于所述运动参数图像中相连续的目标区域确定一个或多个带状区域;控制所述处理器确定所述一个或多个带状区域中满足预设条件的目标带状区域为所述主传播路径。
- 如权利要求1至3中任意一项所述的弹性成像方法,其特征在于,所述弹性成像方法还包括:控制所述探头在接收到所述发射电路的激励时序时振动,以在所述受测组织内产生所述剪切波。
- 如权利要求3所述的弹性成像方法,其特征在于,每一目标区域对应目标时刻范围,每一目标时刻范围包括若干目标时刻,所述弹性成像方法还包括:控制所述处理器获取所述探头振动结束时所对应的参考时刻;其中,所述控制所述处理器确定所述一个或多个带状区域中满足预设条件的目标带状区域为所述主传播路径包括:控制所述处理器确定所述一个或多个带状区域中目标时刻晚于所述参考时刻的目标区域;控制所述处理器确定所述一个或多个带状区域中目标时刻晚于所述参考时刻的目标区域所组成的带状区域为所述主传播路径。
- 如权利要求3所述的弹性成像方法,其特征在于,所述控制所述处理器确定所述一个或多个带状区域中满足预设条件的目标带状区域为所述主传播路径包括:控制所述处理器确定位于预设深度下的目标带状区域为所述主传播路径。
- 如权利要求3所述的弹性成像方法,其特征在于,所述控制所述处理器确定所述一个或多个带状区域中满足预设条件的目标带状区域为所述主传播路径包括:控制所述处理器确定所述一个或多个带状区域中具有最大长度或者最大面积的目标带状区域为所述主传播路径。
- 如权利要求1所述的弹性成像方法,其特征在于,所述控制所述处理器确定所述运动参数图像中所述剪切波的主传播路径包括:控制所述处理器对所述运动参数图像进行二值化处理,其中,二值化处理后的所述运动参数图像为所述主传播路径图。
- 如权利要求8所述的弹性成像方法,其特征在于,所述运动参数图像包括若干像素点,每一像素点的像素值与像素点所对应的深度下的运动参数的大小相对应,其中所述控制所述处理器对所述运动参数图像进行二值化处理包括:控制所述处理器将所述运动参数图像中像素值大于预设阈值的像素点设置为第一颜色;控制所述处理器将所述运动参数图像中像素值不大于所述预设阈值的像素点设置为第二颜色。
- 如权利要求8所述的弹性成像方法,其特征在于,所述控制所述处理器对所述运动参数图像进行二值化处理包括:控制所述处理器将所述运动参数图像中所述主传播路径所对应的目标带状区域设置为第一颜色;控制所述处理器将所述主传播路径所对应的目标带状区域之外的区域设置为第二颜色。
- 如权利要求3所述的弹性成像方法,其特征在于,所述控制所述处理器 将所述主传播路径图显示于所述显示屏内,包括:控制所述处理器将所述主传播路径所对应的目标带状区域中每一深度处的像素点的像素值设置为具有与运动参数对应的第三颜色,其中,不同的运动参数所对应的第三颜色不同;控制所述处理器将所述主传播路径所对应的目标带状区域之外的区域设置为第四颜色。
- 如权利要求1至11中任意一项所述的弹性成像方法,其特征在于,所述弹性成像方法还包括:控制所述处理器确定所述受测组织的弹性信息的置信度。
- 如权利要求12所述的弹性成像方法,其特征在于,所述弹性成像方法还包括:控制所述处理器显示与所述受测组织的弹性信息的置信度相对应的提示信息。
- 如权利要求12或13所述的弹性成像方法,其特征在于,所述控制所述处理器确定所述受测组织的弹性信息的置信度,包括:控制所述处理器确定所述主传播路径所对应的一个或多个置信度参数;控制所述处理器基于所述一个或多个置信度参数确定所述受测组织的弹性信息的置信度。
- 如权利要求14所述的弹性成像方法,其特征在于,所述置信度参数包括所述主传播路径的线性度参数、所述主传播路径直线拟合计算所述剪切波传播速度时的误差参数、所述主传播路径的长度参数、所述主传播路径的面积参数中的一个或多个。
- 如权利要求13所述的弹性成像方法,其特征在于,所述控制所述处理器显示与所述受测组织的弹性信息的置信度相对应的提示信息,包括:控制所述处理器获取所述受测组织的基础图像;控制所述处理器将所述基础图像及与所述受测组织的弹性信息的置信度相对应的提示信息显示于所述显示屏内。
- 如权利要求16所述的弹性成像方法,其特征在于,所述控制所述处理器获取所述受测组织的基础图像,包括:控制所述探头在接收到所述发射电路的第二发射时序时向所述受测组织发射第二超声波;控制所述探头接收所述受测组织返回的第二超声回波,并将所述第二超声回波转换为电信号后传输至所述接收电路;控制所述波束合成器对所述接收电路传输来的电信号进行波束合成,获得第二超声回波数据;控制所述处理器基于所述第二超声回波数据生成所述基础图像。
- 如权利要求17所述的弹性成像方法,其特征在于,所述基础图像包括B图像、C图像中的一种或多种。
- 一种弹性成像方法,其特征在于,包括:向受测组织发射第一超声波,以跟踪在所述受测组织内传播的剪切波;接收所述受测组织返回的第一超声回波,获得第一超声回波数据;根据所述第一超声回波数据获得由所述剪切波在所述受测组织中的传播引起的所述受测组织在不同时刻及不同深度下的运动参数;根据所述运动参数确定所述剪切波的主传播路径,获得主传播路径图,其中所述主传播路径图表征所述剪切波在所述受测组织中的主传播路径;根据所述第一超声回波数据或者所述运动参数或者所述主传播路径确定所述受测组织的弹性信息;显示所述主传播路径图和所述受测组织的弹性信息。
- 如权利要求19所述的弹性成像方法,其特征在于,所述运动参数包括位移、速度或者应变。
- 如权利要求19或者20所述的弹性成像方法,其特征在于,所述根据所述运动参数确定所述剪切波的主传播路径包括:从所述运动参数中确定满足预设条件的目标运动参数;根据所述目标运动参数对应的深度和时刻获得所述主传播路径。
- 如权利要求21所述的弹性成像方法,其特征在于,所述预设条件为:大于预设阈值。
- 如权利要求21所述的弹性成像方法,其特征在于,所述预设条件为:在预设范围内。
- 如权利要求19至23中任意一项所述的弹性成像方法,其特征在于,还包括:根据所述主传播路径确定所述受测组织的弹性信息的置信度。
- 如权利要求24所述的弹性成像方法,其特征在于,根据所述主传播路径确定所述受测组织的弹性信息的置信度包括:根据所述主传播路径确定所述主传播路径所对应的一个或多个置信度参数;根据所述一个或多个置信度参数确定所述受测组织的弹性信息的置信度。
- 如权利要求25所述的弹性成像方法,其特征在于,所述置信度参数包括所述主传播路径的线性度参数、所述主传播路径直线拟合计算所述剪切波传播速度时的误差参数、所述主传播路径的长度参数、所述主传播路径的面积参数中的一个或多个。
- 如权利要求19至26中任意一项所述的弹性成像方法,其特征在于,还包括:获取所述受测组织的基础图像;同时显示所述受测组织的基础图像、所述主传播路径图和所述受测组织的弹性信息。
- 如权利要求27所述的弹性成像方法,其特征在于,所述基础图像包括B图像、C图像中的一种或多种。
- 一种弹性成像方法,其特征在于,包括:向受测组织发射第一超声波,以跟踪在所述受测组织内传播的剪切波;接收所述受测组织返回的第一超声回波,获得第一超声回波数据;根据所述第一超声回波数据获得由所述剪切波在所述受测组织中的传播引起的所述受测组织在不同时刻及不同深度下的运动参数;根据所述运动参数确定所述剪切波的主传播路径,获得主传播路径图,其中所述主传播路径图表征所述剪切波在所述受测组织中的主传播路径;显示所述主传播路径图。
- 一种弹性成像方法,其特征在于,所述弹性成像方法包括:获取受测组织的运动参数图像;根据所述运动参数图像确定在所述受测组织内传播的剪切波的主传播路径;显示所述主传播路径。
- 如权利要求30所述的弹性成像方法,其特征在于,所述根据所述运动参数图像确定在所述受测组织内传播的剪切波的主传播路径包括:获取所述运动参数图像中一个或多个带状区域;确定所述一个或多个带状区域中满足预设条件的目标带状区域为所述主传播路径。
- 如权利要求31所述的弹性成像方法,其特征在于,所述运动参数图像包括深度及时间的属性信息,所述确定所述一个或多个带状区域中满足预设条件的目标带状区域为所述主传播路径包括:选择所述一个或多个带状区域中时间的属性信息晚于预设时刻的目标带状区域为所述主传播路径;或者选择所述一个或多个带状区域中深度的属性信息位于预设深度下的目标带状区域为所述主传播路径;或者选择所述一个或多个带状区域中具有最大长度或者最大面积的目标带状区域为所述主传播路径。
- 如权利要求30至32中任意一项所述的弹性成像方法,其特征在于,所述主传播路径包括位于所述运动参数图像中的带状区域,所述显示所述主传播路径包括:将所述运动参数图像中所述主传播路径所对应的带状区域设置为第一颜色;将所述主传播路径所对应的带状区域之外的区域设置为第二颜色。
- 如权利要求30至32中任意一项所述的弹性成像方法,其特征在于,所述主传播路径包括位于所述运动参数图像中的带状区域,所述显示所述主传播路径包括:将所述主传播路径所对应的带状区域中每一深度处的像素点的像素值设置为具有与运动参数对应的第三颜色,其中,不同的运动参数所对应的第三颜色不同;将所述主传播路径所对应的目标带状区域之外的区域设置为第四颜色。
- 如权利要求30至34中任意一项所述的弹性成像方法,其特征在于,所述弹性成像方法还包括:确定所述受测组织的弹性信息的置信度。
- 如权利要求35所述的弹性成像方法,其特征在于,所述确定所述受测组织的弹性信息的置信度包括:确定所述主传播路径所对应的一个或多个置信度参数;基于所述一个或多个置信度参数确定所述受测组织的弹性信息的置信度。
- 如权利要求36所述的弹性成像方法,其特征在于,所述置信度参数包括所述主传播路径的线性度参数、所述主传播路径直线拟合计算所述剪切波传播速度时的误差参数、所述主传播路径的长度参数、所述主传播路径的面积参数中的一个或多个。
- 一种弹性成像系统,其特征在于,所述弹性成像系统包括:探头,用于向受测组织发射第一超声波,以跟踪在所述受测组织内传播的剪切波,所述探头还用于接收所述受测组织返回的第一超声回波,获得第一超声回波数据;处理器,连接于所述探头,所述处理器用于基于所述第一超声回波数据获得由所述剪切波在所述受测组织中的传播引起的所述受测组织在不同时刻及不同深度下的运动参数,根据所述运动参数确定所述剪切波的主传播路径,获得主传播路径图,并根据所述第一超声回波数据或者所述运动参数或者所述主传播路径图确定所述受测组织的弹性信息,其中所述主传播路径图表征所述剪切波在所述受测组织中的主传播路径;显示屏,连接于所处理器,所述处理器用于将所述主传播路径图和所述受测组织的弹性信息显示于所述显示屏内。
- 一种计算机可读存储介质,存储有计算机指令,其特征在于,所述计算机指令被处理器执行时实现如权利要求1至37中任意一项所述的弹性成像方法。
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