WO2021025440A2 - Device for removing thrombi in varicose vein using thrombus collecting mesh and thrombus suction catheter, and method for using same - Google Patents

Device for removing thrombi in varicose vein using thrombus collecting mesh and thrombus suction catheter, and method for using same Download PDF

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Publication number
WO2021025440A2
WO2021025440A2 PCT/KR2020/010286 KR2020010286W WO2021025440A2 WO 2021025440 A2 WO2021025440 A2 WO 2021025440A2 KR 2020010286 W KR2020010286 W KR 2020010286W WO 2021025440 A2 WO2021025440 A2 WO 2021025440A2
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Prior art keywords
thrombus
blood
vein
net
clot
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PCT/KR2020/010286
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French (fr)
Korean (ko)
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WO2021025440A3 (en
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박의준
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계명대학교 산학협력단
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Publication of WO2021025440A2 publication Critical patent/WO2021025440A2/en
Publication of WO2021025440A3 publication Critical patent/WO2021025440A3/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/221—Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/22031—Gripping instruments, e.g. forceps, for removing or smashing calculi
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/84—Drainage tubes; Aspiration tips
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/22031—Gripping instruments, e.g. forceps, for removing or smashing calculi
    • A61B2017/22034—Gripping instruments, e.g. forceps, for removing or smashing calculi for gripping the obstruction or the tissue part from inside
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22038—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with a guide wire
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22072—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with an instrument channel, e.g. for replacing one instrument by the other
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22079—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with suction of debris
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22094—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for for crossing total occlusions, i.e. piercing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/221—Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions
    • A61B2017/2212—Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions having a closed distal end, e.g. a loop
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2217/00—General characteristics of surgical instruments
    • A61B2217/002—Auxiliary appliance
    • A61B2217/005—Auxiliary appliance with suction drainage system

Definitions

  • the present invention relates to a lower extremity vein thrombus eliminator and a method of using the same, and more particularly, to a lower extremity vein thrombus eliminator using a blood clot collection net and a thrombus suction catheter, and a method of using the same.
  • deep vein thrombosis is a disease that causes symptoms of swelling of the lower extremities, and seriously causes pulmonary embolism, leading to respiratory distress or death. It occurs mainly in the veins of the lower extremities.
  • Treatment with an anticoagulant or in case of severe blood clots is removed by dissolving the clots using a thrombolytic agent while removing the clots with a catheter.
  • the method of removing a blood clot using a conventional catheter is a process of repeatedly inserting a catheter and aspirating blood clots in a thick vein, which has potential problems of (1) blood vessel damage, (2) valve damage, and (3) procedure.
  • various types of devices for mechanically removing blood clots are being developed, but they must be applicable to blood vessels of various thicknesses, minimize embolization, do not damage venous valves, and be bent and curved. It was difficult to effectively remove blood clots from veins and to satisfy all safety requirements that the amount of blood loss should be small.
  • the general method of removing blood clots is (1) diagnosing venous thrombosis by ultrasound or CT, (2) installing a filter in the inferior vena cava when the risk of pulmonary embolization of blood clots is high, and (3) a multi-side hole catheter. ) Is placed in the iliac vein blocked by a blood clot, and a thrombolytic agent is continuously injected for more than 12 hours to partially dissolve the blood clot, and (4) mechanically remove the clot using a catheter or other device. At this time, if the stricture causing the blood clot remains, it is made by inserting a stent.
  • the problem of embolization is the step of mechanical blood clot removal in (4), where the instrument is used in the conventional clot removal method described above, and is a thick catheter (6Fr, about 2.5 mm) close to a straight line.
  • the blood clot is passively aspirated with an outer diameter), which is a simple and very primitive method as shown in FIG. 1.
  • the problem of bleeding, upper embolism, and blood vessel damage can be controlled to some extent by the operator, but as shown in FIG. 2, thrombi in a specific region of the bend due to the limitation of the instrument are thrombosis with a straightened catheter. There is a disadvantage in that it cannot be removed.
  • a method of crushing the blood clots into small pieces using a mechanical grinder is used, which is made by twisting wires and potentially risking pulmonary embolism.
  • the present invention has been proposed in order to solve the above problems of the previously proposed methods, a guide guide tube having a guide wire that is mounted up to a normal vein through a lesion of a vein closed by a thick blood clot, and a guide guide tube A sheath that is guided along the vein and mounted at an appropriate blood vessel position for removal of blood clots from a vein, a clot removal net that is installed in a catheter inserted into the sheath and spreads out from a normal blood vessel through the clot, and a clot removal net that is inserted into the sheath and collected in the clot removal net.
  • a vein thrombus eliminator using a blood clot collection net and a clot inhalation catheter that allows easy removal of clots in veins closed by thick clots without depending on the skill of the operator, and Its purpose is to provide a method of use.
  • the present invention can be applied to blood vessels of various thicknesses by collecting and aspirating venous thrombus using a thrombus removal net and a suction catheter, and in particular, unnecessary bleeding in curved and curved veins, upper Another object of the present invention is to provide a lower extremity vein thrombus eliminator using a mesh for collecting thrombi and a thrombus suction catheter, and a method of using the same, to minimize embolization, damage to blood vessels, residual blood clots, and blood loss.
  • the venous blood clot remover using a mesh for collecting blood clots and a blood clot suction catheter according to the features of the present invention
  • Introducer (introducer) having a guide wire that is mounted by passing through the lesion of the vein closed by a thick blood clot to the normal vein;
  • a blood clot removal net that is mounted on a catheter inserted into the sheath and spreads through the blood clot in normal blood vessels;
  • It is characterized in that it comprises a suction catheter inserted into the sheath to suck the blood clots collected in the clot removal net.
  • the guide guide pipe Preferably, the guide guide pipe,
  • the sheath When the sheath is mounted, it can function as a necessary guide pipe.
  • the sheath may be removed after being mounted at an appropriate blood vessel position for removing blood clots in a vein.
  • the sheath Preferably, the sheath,
  • Fr Fr size
  • the blood clot removal net Preferably, the blood clot removal net
  • the blood clot removal net More preferably, the blood clot removal net
  • One end of a long thin wire can be configured in a structure in which the net is unfolded in an oval shape.
  • the blood clot removal net Even more preferably, the blood clot removal net,
  • One end of the elongated wire has a structure in which the net is unfolded in an oval shape, but the net at the rear end area where the blood clot is collected may be formed more densely.
  • the suction catheter More preferably, the suction catheter,
  • a plurality of side holes for aspiration of blood clots collected in the clot removal net may be further formed.
  • the suction catheter Even more preferably, the suction catheter,
  • It may be configured in a form having a flexible tube shape having an elongated shape that further forms a plurality of side holes for aspiration of the blood clots collected in the clot removal net, and a slightly curved end.
  • the suction catheter Even more preferably, the suction catheter,
  • the sheath has a size of a diameter that can fit into the inner diameter of the sheath, but may be configured with a diameter of 8 to 11 Fr (French size).
  • the sheath in a state in which a guide guide tube having a guide wire is mounted through the step (1), the sheath is guided along the guide guide tube to be mounted at an appropriate blood vessel position for removing blood clots from a vein;
  • a suction catheter is inserted into the sheath to suck the thrombus collected in the thrombus removal net.
  • the guide guide pipe Preferably, the guide guide pipe,
  • the sheath When the sheath is mounted, it can function as a necessary guide pipe.
  • the sheath may be removed after being mounted at an appropriate blood vessel position for removing blood clots in a vein.
  • the sheath Preferably, the sheath,
  • Fr Fr size
  • the blood clot removal net Preferably, the blood clot removal net
  • the blood clot removal net More preferably, the blood clot removal net
  • One end of a long thin wire can be configured in a structure in which the net is unfolded in an oval shape.
  • the blood clot removal net Even more preferably, the blood clot removal net,
  • One end of the elongated wire has a structure in which the net is unfolded in an oval shape, but the net at the rear end area where the blood clot is collected may be formed more densely.
  • the suction catheter More preferably, the suction catheter,
  • a plurality of side holes for aspiration of blood clots collected in the clot removal net may be further formed.
  • the suction catheter Even more preferably, the suction catheter,
  • It may be configured in a form having a flexible tube shape having an elongated shape that further forms a plurality of side holes for aspiration of the blood clots collected in the clot removal net, and a slightly curved end.
  • the suction catheter Even more preferably, the suction catheter,
  • the sheath has a size of a diameter that can fit into the inner diameter of the sheath, but may be configured with a diameter of 8 to 11 Fr (French size).
  • a guide wire provided with a guide wire that goes up to a normal vein through a lesion of a vein closed by a thick thrombus
  • the sheath is guided along the tube and the guiding tube and placed at an appropriate blood vessel location for removal of blood clots from the vein, a clot removal net that is attached to a catheter that is inserted into the sheath and spreads from a normal blood vessel through the blood clot, and is inserted into the sheath.
  • the venous thrombus can be collected and removed by aspiration using a thrombus removal net and a suction catheter, so that the thickness is increased. It can be applied to various blood vessels, and in particular, it is possible to minimize unnecessary bleeding, upper embolization, blood vessel damage, residual blood clots, and blood loss in a curved and curved vein.
  • FIG. 1 is a diagram showing the configuration of a catheter device used in a conventional method for removing blood clots.
  • FIG. 2 is a view showing a configuration of a venous blood vessel insertion of a catheter device used in a conventional method for removing blood clots.
  • FIG. 3 is a diagram showing a configuration of a blood clot crushing device and a venous blood vessel insertion device used in a conventional method for removing blood clots.
  • FIG. 4 is a diagram showing the configuration of a vein thrombus remover using a blood clot collection net and a blood clot suction catheter according to an embodiment of the present invention as a functional block.
  • FIG. 5 is a view schematically showing the configuration of a vein thrombus remover using a blood clot collection net and a blood clot suction catheter according to an embodiment of the present invention.
  • FIG. 6 is a view showing the configuration of a blood clot removal net of a vein thrombus remover using a blood clot collection net and a clot suction catheter according to an embodiment of the present invention.
  • FIG. 7 is a view showing the configuration of another example of a vein thrombus remover using a blood clot collection net and a blood clot suction catheter according to an embodiment of the present invention.
  • FIG. 8 is a view showing a flow of a method of using a vein thrombus remover using a blood clot collecting net and a blood clot suction catheter according to an embodiment of the present invention.
  • FIGS. 9 to 12 are diagrams illustrating a procedure for removing blood clots according to a sequence of a method of using a vein thrombus remover using a blood clot collection net and a blood clot suction catheter according to an embodiment of the present invention.
  • S120 A step in which the sheath is guided along the guiding tube and placed at an appropriate blood vessel position for removing blood clots from the vein
  • FIG. 4 is a diagram showing the configuration of a vein thrombus remover using a blood clot collecting net and a thrombus suction catheter according to an embodiment of the present invention as a functional block
  • FIG. 5 is a diagram for collecting blood clots according to an embodiment of the present invention.
  • FIG. 6 is a blood clot removal network of the lower extremity vein thrombus remover using a thrombus collecting mesh and a thrombus suction catheter according to an embodiment of the present invention
  • FIG. 6 is a blood clot removal network of the lower extremity vein thrombus remover using a thrombus collecting mesh and a thrombus suction catheter according to an embodiment of the present invention
  • the lower extremity vein thrombus remover 100 using a thrombus collecting net and a thrombus suction catheter according to an embodiment of the present invention includes a guide guide tube 110, a sheath 120 It may be configured to include a blood clot removal net 130, and a suction catheter 140.
  • the guide guide tube 110 is configured to include a guide wire 111 that passes through a lesion of a vein closed by a thick blood clot and is mounted up to a normal vein.
  • a guide wire 111 that passes through a lesion of a vein closed by a thick blood clot and is mounted up to a normal vein.
  • Such an introducer 110 functions as a guide conduit required when mounting the sheath 120 as shown in FIG. 5.
  • the guide guide tube 110 may be removed after the sheath 120 is mounted at an appropriate blood vessel position for removing blood clots in a vein.
  • the sheath 120 is guided along the guide guide tube 110 and mounted at an appropriate blood vessel position for removing blood clots from a vein.
  • This sheath 120 serves as a protective sheath that allows the use of a clot removal net 130 and an inhalation catheter 140, which will be described later, to remove a lesion of a vein closed by a thick thrombus, that is, a venous thrombus. do.
  • the sheath 120 may be configured with a diameter of 9 to 12 Fr (French size) that can be mounted in a thick venous blood vessel.
  • the blood clot removal net 130 is mounted on the catheter 131 inserted into the sheath 120 and is a structure of a net that passes through the clot and unfolds in normal blood vessels.
  • the blood clot removal net 130 is mounted so as to be mounted inside the catheter 131 made of a flexible tube having an elongated shape, and spreads through a blood clot in a vein in a normal blood vessel and then pulls down the clot. Can function to capture within.
  • the blood clot removal net 130 may be configured in a structure in which the net is unfolded in an oval shape with one end of an elongated wire, as shown in FIG. 6.
  • the blood clot removal net 130 has a structure in which the net is unfolded in an elliptical shape with one end of a long thin wire, and the net in the rear end area where the clot is collected may be formed more densely.
  • 6 shows the configuration of a blood clot removal net of a vein thrombus remover using a blood clot collecting net and a clot suction catheter according to an embodiment of the present invention.
  • 6A shows a configuration in which the blood clot removal net 130 is mounted on the catheter 131 having an elongated tube shape.
  • 6B shows a configuration in which the blood clot removal net 130 is drawn out from the elongated tube-shaped catheter 131 and unfolded.
  • 6(c) shows the shape of a mesh that is pulled to collect blood clots in a state in which the blood clot removal net 130 is pulled out from the catheter 131 in the shape of a long thin tube and is unfolded.
  • the suction catheter 140 is a configuration of an inhalation catheter that is inserted into the sheath 120 and sucks a blood clot collected in the blood clot removal net 130.
  • the suction catheter 140 is a flexible tube having an elongated shape, and has a plurality of side holes 141 for aspiration of blood clots collected in the clot removal net 130. Can be further formed.
  • the suction catheter 140 has a flexible tube shape of an elongated shape that further forms a plurality of side holes 141 for aspiration of blood clots collected in the blood clot removal net 130, and the end is slightly curved. It can be configured in a form.
  • the suction catheter 140 may be configured to have a size of a diameter that can enter the inner diameter of the sheath 120 depending on the thickness of the sheath 120, preferably 8 to 11 Fr (French size) Can be configured.
  • the suction catheter 140 is configured to have a diameter of 8 to 11 Fr that can be inserted into the sheath 120 according to the thickness of the sheath 120 of 9 to 12 Fr, but is not limited thereto, and the thickness of the sheath 120 It is preferred that it is understood to have a corresponding diameter that can be inserted according to.
  • FIG. 7 is a block diagram illustrating another example of a lower extremity vein thrombus eliminator using a blood clot collection net and a blood clot suction catheter according to an embodiment of the present invention.
  • another example of the lower extremity vein thrombus remover 100 is a double tube in which the tube of the sheath 120 is branched, and a thrombus removal net 130 is inserted into the branched upper tube.
  • the blood clots are collected, and the suction catheter 140 is inserted into the branched lower tube so that the blood clots collected by the clot removal net 130 can be sucked.
  • FIG. 8 is a view showing a flow of a method of using a vein thrombus remover using a blood clot collection net and a thrombus suction catheter according to an embodiment of the present invention
  • FIGS. 9 to 12 are diagrams according to an embodiment of the present invention. It is a diagram showing a blood clot removal process according to the sequence of a method of using a venous blood clot remover using a blood clot collection net and a clot suction catheter. As shown in FIG.
  • a method of using a lower extremity vein thrombus eliminator using a blood clot collection net and a thrombus suction catheter is a vein in which a guide guide tube having a guide wire is closed with a thick blood clot.
  • It may be implemented including a step (S130) of being inserted into the blood clot and unfolding in a normal blood vessel (S130), and a step (S140) of aspirating the blood clot collected in the blood clot removal net by the suction catheter.
  • step S110 the guide guide tube 110 provided with the guide wire 111 passes through the lesion of the vein closed by a thick thrombus and is mounted up to a normal vein.
  • the guide guide pipe 110 in this step S110 functions as a guide pipe required when mounting the sheath 120, as shown in FIG. 9.
  • the guide guide tube 110 may be removed for use of the blood clot removal net 130 and the suction catheter 140 after the sheath 120 is mounted at an appropriate blood vessel position for removing blood clots from a vein.
  • step S120 in a state in which the guide guide tube 110 having the guide wire 111 is mounted through the step S110, the sheath 120 is guided along the guide guide tube 110 to remove blood clots in the vein. It is mounted in the blood vessel position.
  • the sheath 120 in this step S120 serves as a protective sheath that enables the use of the clot removal net 130 and the suction catheter 140 to remove a lesion of a vein closed by a thick blood clot, that is, venous blood clot, Preferably, it may be configured with a diameter of 9 to 12 Fr (French size) that can be mounted in a thick vein vessel.
  • step S130 the blood clot removal net 130 mounted on the catheter 131 is inserted into the sheath 120 to pass through the blood clot and unfold in the normal blood vessel.
  • the blood clot removal net 130 in this step S130 is mounted so as to be mounted inside the catheter 131 made of a flexible tube having an elongated shape, as shown in FIGS. 10 and 11, respectively, The blood clot is collected in the net as it passes through the clot and spreads out of the normal blood vessel and is pulled down.
  • the blood clot removal net 130 has a structure in which the net is spread in an oval shape with one end of a long thin wire, and the net in the rear end area where the clot is collected may be formed more densely. .
  • step S140 the suction catheter 140 is inserted into the sheath 120 to suck the blood clots collected in the clot removal net 130.
  • the suction catheter 140 in this step S140 as shown in Figure 12, the flexibility of the elongated shape through the plurality of side holes 141 formed at the end of the tube to remove the blood clots collected in the net 130 It is removed by suction.
  • the suction catheter 140 is a flexible tube having an elongated shape, as shown in FIG. 5, and a plurality of side holes 141 for aspiration of blood clots collected in the clot removal net 130 This is formed, and the end of the tube in which the plurality of side holes 141 are formed is configured in a slightly curved shape.
  • the suction catheter 140 may have a diameter of 8 to 11 Fr (French size) having a size of a diameter that can enter the inner diameter of the sheath 120 depending on the thickness of the sheath 120.
  • the lower extremity vein thrombus eliminator using a blood clot collection net and a thrombus suction catheter is a guide that goes up to a normal vein through a lesion of a vein closed by a thick thrombus.
  • a catheter inserted into the sheath and spreads out from the normal blood vessel through the blood clot
  • an inhalation catheter that is inserted into the sheath and sucks the blood clots collected in the clot removal net
  • it is possible to easily remove the clots in the veins closed by thick clots without depending on the skill of the operator.
  • By collecting and aspirating venous thrombus using a removal net and a suction catheter it can be applied to blood vessels of various thicknesses. In particular, unnecessary bleeding from curved and curved veins, upper embolism, blood vessel damage, blood clots It is possible to minimize residual and blood loss.

Abstract

Proposed in the present invention are a device for removing thrombi in varicose veins using a thrombus collecting mesh and a thrombus suction catheter, and a method for using same, the device comprising: a guide delivery tube which is provided with a guide wire that passes through lesions in the vein obstructed by thick thrombi, and ascends to a normal area of the vein to be mounted thereto; a sheath which is guided along the guide delivery tube and mounted to an appropriate blood vessel position for removing the thrombi in the vein; a thrombus collecting mesh which is mounted to the catheter inserted into the sheath, and passes through the thrombi and spreads out in the normal area of the blood vessel; and a suction catheter which is inserted into the sheath and suctions the thrombi collected in the thrombus collecting mesh. Accordingly, the thrombi in the vein obstructed by the thick thrombi can be easily removed without depending on the skill of a clinician.

Description

혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기 및 그 이용 방법Leg vein thrombus eliminator using a blood clot collection net and a thrombus suction catheter and its use method
본 발명은 하지정맥 혈전 제거기 및 그 이용 방법에 관한 것으로서, 보다 구체적으로는 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기 및 그 이용 방법에 관한 것이다.The present invention relates to a lower extremity vein thrombus eliminator and a method of using the same, and more particularly, to a lower extremity vein thrombus eliminator using a blood clot collection net and a thrombus suction catheter, and a method of using the same.
일반적으로 심부정맥혈전증은 하지 부종의 증상을 유발하며, 심각하게는 폐동맥 색전증을 일으켜 호흡곤란이나 사망에 이르게 하는 질환이다. 주로 하지의 정맥에 발생하는데, 항응고제를 사용하여 치료하거나, 혈전이 심한 경우에는 카테터를 이용하여 혈전을 제거하면서 혈전 용해제를 사용하여 혈전을 녹여서 제거한다.In general, deep vein thrombosis is a disease that causes symptoms of swelling of the lower extremities, and seriously causes pulmonary embolism, leading to respiratory distress or death. It occurs mainly in the veins of the lower extremities. Treatment with an anticoagulant or in case of severe blood clots is removed by dissolving the clots using a thrombolytic agent while removing the clots with a catheter.
기존의 카테터를 이용하여 혈전을 제거하는 방법은, 굵은 정맥에서 반복적인 카테터 삽입과 혈전 흡인을 하는 과정으로 (1) 혈관 손상, (2) 밸브 손상의 잠재적인 문제를 가지고 있으며, (3) 시술 중 혈전을 떠내려 보내 폐색전을 일으키는 문제, 그리고 (4) 굽어져서 돌아가는 혈관에서 혈전의 흡인이 불완전할 뿐 아니라, (5) 혈전과 함께 다량의 혈액을 함께 흡인함에 따른 혈액 소실의 위험이 있다. 이에 따라 혈전을 기계적으로 제거하는 여러 가지 형태의 기구들이 개발되고는 있으나, 굵기가 다양한 혈관에 적용할 수 있어야 하고, 색전 발생을 최소화하여야 하며, 정맥 밸브의 손상이 없어야 하고, 굽어져 있고 굴곡 있는 정맥에서도 효과적으로 혈전을 제거할 수 있으며, 혈액 소실의 양이 적어야 하는 안전의 조건을 모두 만족하기에는 어려움이 있었다.The method of removing a blood clot using a conventional catheter is a process of repeatedly inserting a catheter and aspirating blood clots in a thick vein, which has potential problems of (1) blood vessel damage, (2) valve damage, and (3) procedure. There is a risk of blood loss due to aspiration of blood clots together with blood clots, as well as (4) incomplete aspiration of blood clots from bent and rotating blood vessels. Accordingly, various types of devices for mechanically removing blood clots are being developed, but they must be applicable to blood vessels of various thicknesses, minimize embolization, do not damage venous valves, and be bent and curved. It was difficult to effectively remove blood clots from veins and to satisfy all safety requirements that the amount of blood loss should be small.
현재 일반적인 혈전 제거의 방법은, (1) 초음파 또는 CT로 정맥혈전증을 진단하고, (2) 혈전의 폐색전 위험이 큰 경우 하대정맥 내에 필터를 설치하며, (3) 다공성 카테터(multi side hole catheter)를 혈전으로 막힌 장골정맥 내에 거치하여 12시간 이상 혈전 용해제를 지속 주입하여 혈전을 일부 용해시키고, (4) 카테터 등의 기구를 이용하여 기계적으로 혈전을 제거한다. 이때, 혈전의 원인이 되는 협착이 남아있다면, 스텐트(stent)를 삽입하는 과정으로 이루어지고 있다.Currently, the general method of removing blood clots is (1) diagnosing venous thrombosis by ultrasound or CT, (2) installing a filter in the inferior vena cava when the risk of pulmonary embolization of blood clots is high, and (3) a multi-side hole catheter. ) Is placed in the iliac vein blocked by a blood clot, and a thrombolytic agent is continuously injected for more than 12 hours to partially dissolve the blood clot, and (4) mechanically remove the clot using a catheter or other device. At this time, if the stricture causing the blood clot remains, it is made by inserting a stent.
이러한 현재의 일반적인 혈전 제거 방법에서, 색전 제거술의 문제는 앞서 설명한 기존의 혈전 제거 방법에서 기구가 사용되는 (4)의 기계적 혈전 제거의 단계로서, 거의 일직선에 가까운 굵은 카테터(6Fr, 2.5㎜ 정도의 외경)로 수동적으로 혈전을 흡인하게 되는데, 도 1과 같이 단순하며 매우 원초적인 방법의 기구이다. 이러한 기구를 이용하여 혈전을 흡인할 때는 굴곡진 굵은 혈관에서 모양과 방향, 흡인할 혈전을 특정하기가 어렵기 때문에 불필요한 출혈, 상부 색전, 혈관 손상, 혈전의 잔존 등의 문제가 발생할 수 있다.In the current general method of removing blood clots, the problem of embolization is the step of mechanical blood clot removal in (4), where the instrument is used in the conventional clot removal method described above, and is a thick catheter (6Fr, about 2.5 mm) close to a straight line. The blood clot is passively aspirated with an outer diameter), which is a simple and very primitive method as shown in FIG. 1. When a blood clot is aspirated using such a device, since it is difficult to specify the shape and direction of the blood clot to be aspirated in a thick curved blood vessel, problems such as unnecessary bleeding, upper embolization, damage to blood vessels, and residual blood clots may occur.
또한, 출혈이나, 상부 색전, 혈관 손상의 문제는 시술자에 의해 어느 정도 조절이 가능할 수 있으나, 도 2에 도시된 바와 같이, 기구의 한계에 의해 굴곡의 특정 부위의 혈전들은 직선화된 카테터로는 혈전을 제거하지 못하는 단점이 있다. 또한, 일부에서는 잔존 혈전에 대해서, 도 3에 도시된 바와 같이, 기계적 분쇄기를 이용하여 작은 조각으로 혈전을 부숴서 떠내려 보내는 방법을 사용하기도 하는데, 이 분쇄기는 와이어를 꼬아 만든 것으로 잠재적으로 폐색전의 위험이 있고, 혈관의 밸브를 손상시킬 수 있는 문제가 있으며, 기구의 크기가 충분히 크지 않기 때문에 굵은 장골정맥의 굵어진 혈관에서는 효과적이지 못하게 된다.In addition, the problem of bleeding, upper embolism, and blood vessel damage can be controlled to some extent by the operator, but as shown in FIG. 2, thrombi in a specific region of the bend due to the limitation of the instrument are thrombosis with a straightened catheter. There is a disadvantage in that it cannot be removed. In addition, in some cases, as shown in FIG. 3, for residual blood clots, a method of crushing the blood clots into small pieces using a mechanical grinder is used, which is made by twisting wires and potentially risking pulmonary embolism. In addition, there is a problem that can damage the valve of the blood vessel, and because the size of the instrument is not large enough, it is not effective in the thick blood vessel of the thick iliac vein.
본 발명은 기존에 제안된 방법들의 상기와 같은 문제점들을 해결하기 위해 제안된 것으로서, 굵은 혈전으로 폐쇄된 정맥의 병변을 지나 정상적인 정맥까지 올라가서 거치되는 가이드 와이어를 구비하는 안내유도관과, 안내유도관을 따라 유도되어 정맥의 혈전 제거를 위한 적정 혈관 위치에 거치되는 시스와, 시스 내로 삽입되는 카테터에 장착되어 혈전을 지나 정상적인 혈관에서 펼쳐지는 혈전 제거 그물망과, 시스 내로 삽입되어 혈전 제거 그물망에 포집된 혈전을 흡인하는 흡입 카테터를 포함하여 구성함으로써, 시술자의 숙련도에 의존하지 않고도 굵은 혈전으로 폐쇄된 정맥의 혈전을 손쉽게 제거할 수 있도록 하는, 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기 및 그 이용 방법을 제공하는 것을 그 목적으로 한다.The present invention has been proposed in order to solve the above problems of the previously proposed methods, a guide guide tube having a guide wire that is mounted up to a normal vein through a lesion of a vein closed by a thick blood clot, and a guide guide tube A sheath that is guided along the vein and mounted at an appropriate blood vessel position for removal of blood clots from a vein, a clot removal net that is installed in a catheter inserted into the sheath and spreads out from a normal blood vessel through the clot, and a clot removal net that is inserted into the sheath and collected in the clot removal net. By including an inhalation catheter for aspirating blood clots, a vein thrombus eliminator using a blood clot collection net and a clot inhalation catheter that allows easy removal of clots in veins closed by thick clots without depending on the skill of the operator, and Its purpose is to provide a method of use.
또한, 본 발명은, 혈전 제거 그물망과 흡입 카테터를 이용하여 정맥 혈전을 포집하고 흡인하여 제거할 수 있도록 함으로써, 굵기가 다양한 혈관에 적용이 가능하고, 특히 굽어져 있고 굴곡 있는 정맥에서 불필요한 출혈, 상부 색전, 혈관 손상, 혈전의 잔존, 및 혈액 소실의 최소화가 가능하도록 하는, 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기 및 그 이용 방법을 제공하는 것을 또 다른 목적으로 한다.In addition, the present invention can be applied to blood vessels of various thicknesses by collecting and aspirating venous thrombus using a thrombus removal net and a suction catheter, and in particular, unnecessary bleeding in curved and curved veins, upper Another object of the present invention is to provide a lower extremity vein thrombus eliminator using a mesh for collecting thrombi and a thrombus suction catheter, and a method of using the same, to minimize embolization, damage to blood vessels, residual blood clots, and blood loss.
상기한 목적을 달성하기 위한 본 발명의 특징에 따른 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기는,In order to achieve the above object, the venous blood clot remover using a mesh for collecting blood clots and a blood clot suction catheter according to the features of the present invention,
혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기로서,As a vein thrombus eliminator using a blood clot collection net and a blood clot suction catheter,
굵은 혈전으로 폐쇄된 정맥의 병변을 지나 정상적인 정맥까지 올라가서 거치되는 가이드 와이어를 구비하는 안내유도관(introducer);Introducer (introducer) having a guide wire that is mounted by passing through the lesion of the vein closed by a thick blood clot to the normal vein;
상기 안내유도관을 따라 유도되어 정맥의 혈전 제거를 위한 적정 혈관 위치에 거치되는 시스(sheath);A sheath guided along the guide guide tube and mounted at an appropriate blood vessel location for removing blood clots from a vein;
상기 시스 내로 삽입되는 카테터에 장착되어 혈전을 지나 정상적인 혈관에서 펼쳐지는 혈전 제거 그물망; 및A blood clot removal net that is mounted on a catheter inserted into the sheath and spreads through the blood clot in normal blood vessels; And
상기 시스 내로 삽입되어 상기 혈전 제거 그물망에 포집된 혈전을 흡인하는 흡입 카테터를 포함하는 것을 그 구성상의 특징으로 한다.It is characterized in that it comprises a suction catheter inserted into the sheath to suck the blood clots collected in the clot removal net.
바람직하게는, 상기 안내유도관은,Preferably, the guide guide pipe,
상기 시스를 거치시킬 때 필요한 안내도관으로 기능할 수 있다.When the sheath is mounted, it can function as a necessary guide pipe.
더욱 바람직하게는, 상기 안내유도관은,More preferably, the guide guide pipe,
상기 시스가 정맥의 혈전 제거를 위한 적정 혈관 위치에 거치된 후 제거될 수 있다.The sheath may be removed after being mounted at an appropriate blood vessel position for removing blood clots in a vein.
바람직하게는, 상기 시스는,Preferably, the sheath,
굵은 정맥혈관 내에 거치될 수 있는 9 내지 12 Fr(French size)의 직경으로 구성될 수 있다.It may be composed of a diameter of 9 to 12 Fr (French size) that can be mounted in a thick vein vessel.
바람직하게는, 상기 혈전 제거 그물망은,Preferably, the blood clot removal net,
가늘고 긴 형상의 유연성을 갖는 튜브로 이루어지는 카테터의 내부에 거치되도록 장착된 상태에서, 정맥의 혈전을 지나 정상적인 혈관에서 펼쳐진 후 당겨 내려짐에 따라 혈전을 그물망 내에 포집하도록 기능할 수 있다.In a state mounted so as to be mounted inside a catheter made of a flexible tube having an elongated shape, it can function to collect the blood clot in the net as it is unfolded in the normal blood vessel and then pulled down through the blood clot in the vein.
더욱 바람직하게는, 상기 혈전 제거 그물망은,More preferably, the blood clot removal net,
가늘고 긴 와이어의 일단으로 그물망이 타원형으로 펼쳐지는 구조로 구성될 수 있다.One end of a long thin wire can be configured in a structure in which the net is unfolded in an oval shape.
더욱 더 바람직하게는, 상기 혈전 제거 그물망은,Even more preferably, the blood clot removal net,
가늘고 긴 와이어의 일단으로 그물망이 타원형으로 펼쳐지는 구조를 갖되, 혈전이 포집되는 후단 영역의 그물망이 더 조밀하게 형성될 수 있다.One end of the elongated wire has a structure in which the net is unfolded in an oval shape, but the net at the rear end area where the blood clot is collected may be formed more densely.
더욱 바람직하게는, 상기 흡입 카테터는,More preferably, the suction catheter,
가늘고 긴 형상의 유연성을 갖는 튜브로서, 상기 혈전 제거 그물망에 포집된 혈전을 흡인(aspiration)해 내는 복수의 측면공을 더 형성할 수 있다.As a flexible tube having an elongated shape, a plurality of side holes for aspiration of blood clots collected in the clot removal net may be further formed.
더욱 더 바람직하게는, 상기 흡입 카테터는,Even more preferably, the suction catheter,
상기 혈전 제거 그물망에 포집된 혈전을 흡인(aspiration)해 내는 복수의 측면공을 더 형성하는 가늘고 긴 형상의 유연성을 갖는 튜브 형상으로 말단이 약간 굽은 형태로 구성될 수 있다.It may be configured in a form having a flexible tube shape having an elongated shape that further forms a plurality of side holes for aspiration of the blood clots collected in the clot removal net, and a slightly curved end.
더더욱 바람직하게는, 상기 흡입 카테터는,Even more preferably, the suction catheter,
상기 시스의 굵기에 따라 시스의 내경으로 들어갈 수 있는 직경의 크기를 갖되, 8 내지 11 Fr(French size)의 직경으로 구성될 수 있다.Depending on the thickness of the sheath, it has a size of a diameter that can fit into the inner diameter of the sheath, but may be configured with a diameter of 8 to 11 Fr (French size).
상기한 목적을 달성하기 위한 본 발명의 특징에 따른 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기의 이용 방법은,In order to achieve the above object, a method of using a vein thrombus eliminator using a blood clot collection net and a blood clot suction catheter according to the features of the present invention,
혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기의 이용 방법으로서,As a method of using a vein thrombus eliminator using a blood clot collection net and a blood clot suction catheter,
(1) 가이드 와이어를 구비하는 안내유도관이 굵은 혈전으로 폐쇄된 정맥의 병변을 지나 정상적인 정맥까지 올라가서 거치되는 단계;(1) step in which a guide guide tube having a guide wire goes up to a normal vein through a lesion of a vein closed by a thick thrombus and is mounted;
(2) 상기 단계 (1)을 통해 가이드 와이어를 구비하는 안내유도관이 거치된 상태에서, 시스가 상기 안내유도관을 따라 유도되어 정맥의 혈전 제거를 위한 적정 혈관 위치에 거치되는 단계;(2) in a state in which a guide guide tube having a guide wire is mounted through the step (1), the sheath is guided along the guide guide tube to be mounted at an appropriate blood vessel position for removing blood clots from a vein;
(3) 카테터에 장착된 혈전 제거 그물망이 상기 시스 내로 삽입되어 혈전을 지나 정상적인 혈관에서 펼쳐지는 단계; 및(3) the thrombus removal net mounted on the catheter is inserted into the sheath to pass through the thrombus and spread out in a normal blood vessel; And
(4) 흡인 카테터가 상기 시스 내로 삽입되어 상기 혈전 제거 그물망에 포집된 혈전을 흡인하는 단계를 포함하는 것을 그 구성상의 특징으로 한다.(4) A suction catheter is inserted into the sheath to suck the thrombus collected in the thrombus removal net.
바람직하게는, 상기 안내유도관은,Preferably, the guide guide pipe,
상기 시스를 거치시킬 때 필요한 안내도관으로 기능할 수 있다.When the sheath is mounted, it can function as a necessary guide pipe.
더욱 바람직하게는, 상기 안내유도관은,More preferably, the guide guide pipe,
상기 시스가 정맥의 혈전 제거를 위한 적정 혈관 위치에 거치된 후 제거될 수 있다.The sheath may be removed after being mounted at an appropriate blood vessel position for removing blood clots in a vein.
바람직하게는, 상기 시스는,Preferably, the sheath,
굵은 정맥혈관 내에 거치될 수 있는 9 내지 12 Fr(French size)의 직경으로 구성될 수 있다.It may be composed of a diameter of 9 to 12 Fr (French size) that can be mounted in a thick vein vessel.
바람직하게는, 상기 혈전 제거 그물망은,Preferably, the blood clot removal net,
가늘고 긴 형상의 유연성을 갖는 튜브로 이루어지는 카테터의 내부에 거치되도록 장착된 상태에서, 정맥의 혈전을 지나 정상적인 혈관에서 펼쳐진 후 당겨 내려짐에 따라 혈전을 그물망 내에 포집하도록 기능할 수 있다.In a state mounted so as to be mounted inside a catheter made of a flexible tube having an elongated shape, it can function to collect the blood clot in the net as it is unfolded in the normal blood vessel and then pulled down through the blood clot in the vein.
더욱 바람직하게는, 상기 혈전 제거 그물망은,More preferably, the blood clot removal net,
가늘고 긴 와이어의 일단으로 그물망이 타원형으로 펼쳐지는 구조로 구성될 수 있다.One end of a long thin wire can be configured in a structure in which the net is unfolded in an oval shape.
더욱 더 바람직하게는, 상기 혈전 제거 그물망은,Even more preferably, the blood clot removal net,
가늘고 긴 와이어의 일단으로 그물망이 타원형으로 펼쳐지는 구조를 갖되, 혈전이 포집되는 후단 영역의 그물망이 더 조밀하게 형성될 수 있다.One end of the elongated wire has a structure in which the net is unfolded in an oval shape, but the net at the rear end area where the blood clot is collected may be formed more densely.
더욱 바람직하게는, 상기 흡입 카테터는,More preferably, the suction catheter,
가늘고 긴 형상의 유연성을 갖는 튜브로서, 상기 혈전 제거 그물망에 포집된 혈전을 흡인(aspiration)해 내는 복수의 측면공을 더 형성할 수 있다.As a flexible tube having an elongated shape, a plurality of side holes for aspiration of blood clots collected in the clot removal net may be further formed.
더욱 더 바람직하게는, 상기 흡입 카테터는,Even more preferably, the suction catheter,
상기 혈전 제거 그물망에 포집된 혈전을 흡인(aspiration)해 내는 복수의 측면공을 더 형성하는 가늘고 긴 형상의 유연성을 갖는 튜브 형상으로 말단이 약간 굽은 형태로 구성될 수 있다.It may be configured in a form having a flexible tube shape having an elongated shape that further forms a plurality of side holes for aspiration of the blood clots collected in the clot removal net, and a slightly curved end.
더더욱 바람직하게는, 상기 흡입 카테터는,Even more preferably, the suction catheter,
상기 시스의 굵기에 따라 시스의 내경으로 들어갈 수 있는 직경의 크기를 갖되, 8 내지 11 Fr(French size)의 직경으로 구성될 수 있다.Depending on the thickness of the sheath, it has a size of a diameter that can fit into the inner diameter of the sheath, but may be configured with a diameter of 8 to 11 Fr (French size).
본 발명에서 제안하고 있는 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기 및 그 이용 방법에 따르면, 굵은 혈전으로 폐쇄된 정맥의 병변을 지나 정상적인 정맥까지 올라가서 거치되는 가이드 와이어를 구비하는 안내유도관과, 안내유도관을 따라 유도되어 정맥의 혈전 제거를 위한 적정 혈관 위치에 거치되는 시스와, 시스 내로 삽입되는 카테터에 장착되어 혈전을 지나 정상적인 혈관에서 펼쳐지는 혈전 제거 그물망과, 시스 내로 삽입되어 혈전 제거 그물망에 포집된 혈전을 흡인하는 흡입 카테터를 포함하여 구성함으로써, 시술자의 숙련도에 의존하지 않고도 굵은 혈전으로 폐쇄된 정맥의 혈전을 손쉽게 제거할 수 있도록 할 수 있다.According to the lower extremity vein thrombus eliminator using a blood clot collection net and a thrombus suction catheter proposed in the present invention, and a method of using the same, a guide wire provided with a guide wire that goes up to a normal vein through a lesion of a vein closed by a thick thrombus The sheath is guided along the tube and the guiding tube and placed at an appropriate blood vessel location for removal of blood clots from the vein, a clot removal net that is attached to a catheter that is inserted into the sheath and spreads from a normal blood vessel through the blood clot, and is inserted into the sheath. By including an inhalation catheter that sucks blood clots collected in the clot removal net, it is possible to easily remove clots in veins closed by thick clots without depending on the skill of the operator.
또한, 본 발명의 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기 및 그 이용 방법에 따르면, 혈전 제거 그물망과 흡입 카테터를 이용하여 정맥 혈전을 포집하고 흡인하여 제거할 수 있도록 함으로써, 굵기가 다양한 혈관에 적용이 가능하고, 특히 굽어져 있고 굴곡 있는 정맥에서 불필요한 출혈, 상부 색전, 혈관 손상, 혈전의 잔존, 및 혈액 소실의 최소화가 가능하도록 할 수 있다.In addition, according to the lower extremity vein thrombus eliminator using a thrombus collecting net and a thrombus suction catheter of the present invention, and a method of using the same, the venous thrombus can be collected and removed by aspiration using a thrombus removal net and a suction catheter, so that the thickness is increased. It can be applied to various blood vessels, and in particular, it is possible to minimize unnecessary bleeding, upper embolization, blood vessel damage, residual blood clots, and blood loss in a curved and curved vein.
도 1은 종래의 혈전 제거 방법에 사용되는 카테터 기구의 구성을 도시한 도면.1 is a diagram showing the configuration of a catheter device used in a conventional method for removing blood clots.
도 2는 종래의 혈전 제거 방법에 사용되는 카테터 기구의 정맥혈관 삽입 구성을 도시한 도면.2 is a view showing a configuration of a venous blood vessel insertion of a catheter device used in a conventional method for removing blood clots.
도 3은 종래의 혈전 제거 방법에 사용되는 혈전 분쇄 기구 및 정맥혈관 삽입 구성을 도시한 도면.3 is a diagram showing a configuration of a blood clot crushing device and a venous blood vessel insertion device used in a conventional method for removing blood clots.
도 4는 본 발명의 일실시예에 따른 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기의 구성을 기능 블록으로 도시한 도면.4 is a diagram showing the configuration of a vein thrombus remover using a blood clot collection net and a blood clot suction catheter according to an embodiment of the present invention as a functional block.
도 5는 본 발명의 일실시예에 따른 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기의 구성을 개략적으로 도시한 도면.5 is a view schematically showing the configuration of a vein thrombus remover using a blood clot collection net and a blood clot suction catheter according to an embodiment of the present invention.
도 6은 본 발명의 일실시예에 따른 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기의 혈전 제거 그물망의 구성을 도시한 도면.6 is a view showing the configuration of a blood clot removal net of a vein thrombus remover using a blood clot collection net and a clot suction catheter according to an embodiment of the present invention.
도 7은 본 발명의 일실시예에 따른 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기의 다른 일례의 구성을 도시한 도면.7 is a view showing the configuration of another example of a vein thrombus remover using a blood clot collection net and a blood clot suction catheter according to an embodiment of the present invention.
도 8은 본 발명의 일실시예에 따른 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기의 이용 방법의 흐름을 도시한 도면.8 is a view showing a flow of a method of using a vein thrombus remover using a blood clot collecting net and a blood clot suction catheter according to an embodiment of the present invention.
도 9 내지 도 12는 본 발명의 일실시예에 따른 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기의 이용 방법의 순서에 따른 혈전 제거 과정을 도시한 도면.9 to 12 are diagrams illustrating a procedure for removing blood clots according to a sequence of a method of using a vein thrombus remover using a blood clot collection net and a blood clot suction catheter according to an embodiment of the present invention.
<부호의 설명><Explanation of code>
100: 하지정맥 혈전 제거기100: lower limb vein thrombus eliminator
110: 안내유도관110: guide guide
111: 가이드 와이어111: guide wire
120: 시스120: cis
130: 혈전 제거 그물망130: blood clot removal net
131: 카테터131: catheter
140: 흡인 카테터140: suction catheter
141: 측면공141: side ball
S110: 가이드 와이어를 구비하는 안내유도관이 굵은 혈전으로 폐쇄된 정맥의 병변을 지나 정상적인 정맥까지 올라가서 거치되는 단계S110: Step in which the guide guide tube provided with the guide wire passes through the lesion of the vein closed by a thick thrombus and goes up to the normal vein and is mounted
S120: 시스가 안내유도관을 따라 유도되어 정맥의 혈전 제거를 위한 적정 혈관 위치에 거치되는 단계S120: A step in which the sheath is guided along the guiding tube and placed at an appropriate blood vessel position for removing blood clots from the vein
S130: 카테터에 장착된 혈전 제거 그물망이 시스 내로 삽입되어 혈전을 지나 정상적인 혈관에서 펼쳐지는 단계S130: A step in which the blood clot removal net attached to the catheter is inserted into the sheath to pass through the blood clot and unfold in the normal blood vessel
S140: 흡인 카테터가 혈전 제거 그물망에 포집된 혈전을 흡인하는 단계S140: step of aspirating the blood clots collected in the clot removal net by the suction catheter
이하, 첨부된 도면을 참조하여 본 발명이 속하는 기술분야에서 통상의 지식을 가진 자가 본 발명을 용이하게 실시할 수 있도록 바람직한 실시예를 상세히 설명한다. 다만, 본 발명의 바람직한 실시예를 상세하게 설명함에 있어, 관련된 공지 기능 또는 구성에 대한 구체적인 설명이 본 발명의 요지를 불필요하게 흐릴 수 있다고 판단되는 경우에는 그 상세한 설명을 생략한다. 또한, 유사한 기능 및 작용을 하는 부분에 대해서는 도면 전체에 걸쳐 동일한 부호를 사용한다.Hereinafter, preferred embodiments will be described in detail with reference to the accompanying drawings so that those of ordinary skill in the art may easily implement the present invention. However, in describing a preferred embodiment of the present invention in detail, if it is determined that a detailed description of a related known function or configuration may unnecessarily obscure the subject matter of the present invention, the detailed description thereof will be omitted. In addition, the same reference numerals are used throughout the drawings for portions having similar functions and functions.
덧붙여, 명세서 전체에서, 어떤 부분이 다른 부분과 연결 되어 있다고 할 때, 이는 직접적으로 연결 되어 있는 경우뿐만 아니라, 그 중간에 다른 소자를 사이에 두고 간접적으로 연결 되어 있는 경우도 포함한다. 또한, 어떤 구성요소를 포함 한다는 것은, 특별히 반대되는 기재가 없는 한 다른 구성요소를 제외하는 것이 아니라 다른 구성요소를 더 포함할 수 있다는 것을 의미한다.In addition, throughout the specification, when a part is said to be connected to another part, this includes not only the case that it is directly connected, but also the case that it is indirectly connected with another element in the middle. In addition, the inclusion of certain components means that other components may be further included rather than excluding other components unless specifically stated to the contrary.
도 4는 본 발명의 일실시예에 따른 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기의 구성을 기능 블록으로 도시한 도면이고, 도 5는 본 발명의 일실시예에 따른 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기의 구성을 개략적으로 도시한 도면이며, 도 6은 본 발명의 일실시예에 따른 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기의 혈전 제거 그물망의 구성을 도시한 도면이고, 도 7은 본 발명의 일실시예에 따른 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기의 다른 일례의 구성을 도시한 도면이다. 도 4 내지 도 7에 각각 도시된 바와 같이, 본 발명의 일실시예에 따른 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기(100)는, 안내유도관(110), 시스(120), 혈전 제거 그물망(130), 및 흡입 카테터(140)를 포함하여 구성될 수 있다.FIG. 4 is a diagram showing the configuration of a vein thrombus remover using a blood clot collecting net and a thrombus suction catheter according to an embodiment of the present invention as a functional block, and FIG. 5 is a diagram for collecting blood clots according to an embodiment of the present invention. A diagram schematically showing the configuration of a lower extremity vein thrombus remover using a mesh and a thrombus suction catheter, and FIG. 6 is a blood clot removal network of the lower extremity vein thrombus remover using a thrombus collecting mesh and a thrombus suction catheter according to an embodiment of the present invention FIG. 7 is a view showing the configuration of another example of a vein thrombus remover using a blood clot collecting net and a thrombus suction catheter according to an embodiment of the present invention. As shown in Figs. 4 to 7, respectively, the lower extremity vein thrombus remover 100 using a thrombus collecting net and a thrombus suction catheter according to an embodiment of the present invention includes a guide guide tube 110, a sheath 120 It may be configured to include a blood clot removal net 130, and a suction catheter 140.
안내유도관(110)은, 굵은 혈전으로 폐쇄된 정맥의 병변을 지나 정상적인 정맥까지 올라가서 거치되는 가이드 와이어(111)를 구비하는 구성이다. 이러한 안내유도관(introducer)(110)은 도 5에 도시된 바와 같이, 시스(120)를 거치시킬 때 필요한 안내도관으로 기능한다. 여기서, 안내유도관(110)은 시스(120)가 정맥의 혈전 제거를 위한 적정 혈관 위치에 거치된 후 제거될 수 있다.The guide guide tube 110 is configured to include a guide wire 111 that passes through a lesion of a vein closed by a thick blood clot and is mounted up to a normal vein. Such an introducer 110 functions as a guide conduit required when mounting the sheath 120 as shown in FIG. 5. Here, the guide guide tube 110 may be removed after the sheath 120 is mounted at an appropriate blood vessel position for removing blood clots in a vein.
시스(120)는, 안내유도관(110)을 따라 유도되어 정맥의 혈전 제거를 위한 적정 혈관 위치에 거치되는 구성이다. 이러한 시스(sheath)(120)는 굵은 혈전으로 폐쇄된 정맥의 병변, 즉 정맥 혈전 제거를 위해 후술하게 될 혈전 제거 그물망(130)과 흡입 카테터(140)의 사용이 가능하도록 하는 보호 피복관의 역할을 한다. 여기서, 시스(120)는 굵은 정맥혈관 내에 거치될 수 있는 9 내지 12 Fr(French size)의 직경으로 구성될 수 있다.The sheath 120 is guided along the guide guide tube 110 and mounted at an appropriate blood vessel position for removing blood clots from a vein. This sheath 120 serves as a protective sheath that allows the use of a clot removal net 130 and an inhalation catheter 140, which will be described later, to remove a lesion of a vein closed by a thick thrombus, that is, a venous thrombus. do. Here, the sheath 120 may be configured with a diameter of 9 to 12 Fr (French size) that can be mounted in a thick venous blood vessel.
혈전 제거 그물망(130)은, 시스(120) 내로 삽입되는 카테터(131)에 장착되어 혈전을 지나 정상적인 혈관에서 펼쳐지는 그물망의 구성이다. 이러한 혈전 제거 그물망(130)은 가늘고 긴 형상의 유연성을 갖는 튜브로 이루어지는 카테터(131)의 내부에 거치되도록 장착된 상태에서, 정맥의 혈전을 지나 정상적인 혈관에서 펼쳐진 후 당겨 내려짐에 따라 혈전을 그물망 내에 포집하도록 기능할 수 있다.The blood clot removal net 130 is mounted on the catheter 131 inserted into the sheath 120 and is a structure of a net that passes through the clot and unfolds in normal blood vessels. The blood clot removal net 130 is mounted so as to be mounted inside the catheter 131 made of a flexible tube having an elongated shape, and spreads through a blood clot in a vein in a normal blood vessel and then pulls down the clot. Can function to capture within.
또한, 혈전 제거 그물망(130)은 도 6에 도시된 바와 같이, 가늘고 긴 와이어의 일단으로 그물망이 타원형으로 펼쳐지는 구조로 구성될 수 있다.In addition, the blood clot removal net 130 may be configured in a structure in which the net is unfolded in an oval shape with one end of an elongated wire, as shown in FIG. 6.
또한, 혈전 제거 그물망(130)은 가늘고 긴 와이어의 일단으로 그물망이 타원형으로 펼쳐지는 구조를 갖되, 혈전이 포집되는 후단 영역의 그물망이 더 조밀하게 형성될 수 있다.In addition, the blood clot removal net 130 has a structure in which the net is unfolded in an elliptical shape with one end of a long thin wire, and the net in the rear end area where the clot is collected may be formed more densely.
도 6은 본 발명의 일실시예에 따른 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기의 혈전 제거 그물망의 구성을 나타내고 있다. 도 6의 (a)는 혈전 제거 그물망(130)이 가늘고 긴 튜브 형상의 카테터(131)에 장착된 구성을 나타내고 있다. 도 6의 (b)는 혈전 제거 그물망(130)이 가늘고 긴 튜브 형상의 카테터(131)에서 인출되어 펼쳐진 상태의 구성을 나타내고 있다. 도 6의 (c)는 혈전 제거 그물망(130)이 가늘고 긴 튜브 형상의 카테터(131)에서 인출되어 펼쳐진 상태에서 혈전 포집을 위해 당겨진 그물망 형태를 나타내고 있다.6 shows the configuration of a blood clot removal net of a vein thrombus remover using a blood clot collecting net and a clot suction catheter according to an embodiment of the present invention. 6A shows a configuration in which the blood clot removal net 130 is mounted on the catheter 131 having an elongated tube shape. 6B shows a configuration in which the blood clot removal net 130 is drawn out from the elongated tube-shaped catheter 131 and unfolded. 6(c) shows the shape of a mesh that is pulled to collect blood clots in a state in which the blood clot removal net 130 is pulled out from the catheter 131 in the shape of a long thin tube and is unfolded.
흡입 카테터(140)는, 시스(120) 내로 삽입되어 혈전 제거 그물망(130)에 포집된 혈전을 흡인하는 흡입용 카테터의 구성이다. 이러한 흡입 카테터(140)는 도 5에 도시된 바와 같이, 가늘고 긴 형상의 유연성을 갖는 튜브로서, 혈전 제거 그물망(130)에 포집된 혈전을 흡인(aspiration)해 내는 복수의 측면공(141)을 더 형성할 수 있다.The suction catheter 140 is a configuration of an inhalation catheter that is inserted into the sheath 120 and sucks a blood clot collected in the blood clot removal net 130. As shown in FIG. 5, the suction catheter 140 is a flexible tube having an elongated shape, and has a plurality of side holes 141 for aspiration of blood clots collected in the clot removal net 130. Can be further formed.
또한, 흡입 카테터(140)는 혈전 제거 그물망(130)에 포집된 혈전을 흡인(aspiration)해 내는 복수의 측면공(141)을 더 형성하는 가늘고 긴 형상의 유연성을 갖는 튜브 형상으로 말단이 약간 굽은 형태로 구성될 수 있다.In addition, the suction catheter 140 has a flexible tube shape of an elongated shape that further forms a plurality of side holes 141 for aspiration of blood clots collected in the blood clot removal net 130, and the end is slightly curved. It can be configured in a form.
또한, 흡입 카테터(140)는 시스(120)의 굵기에 따라 시스(120)의 내경으로 들어갈 수 있는 직경의 크기를 갖도록 구성될 수 있으며, 바람직하게는 8 내지 11 Fr(French size)의 직경으로 구성될 수 있다. 이러한 흡입 카테터(140)는 9 내지 12 Fr의 시스(120)의 굵기에 따라 그 안으로 들어갈 수 있는 8 내지 11 Fr의 직경을 갖도록 구성하고 있으나, 이에 제한을 두지는 않으며, 시스(120)의 굵기에 따라 삽입이 가능한 대응하는 직경을 갖는 것으로 이해됨이 바람직하다.In addition, the suction catheter 140 may be configured to have a size of a diameter that can enter the inner diameter of the sheath 120 depending on the thickness of the sheath 120, preferably 8 to 11 Fr (French size) Can be configured. The suction catheter 140 is configured to have a diameter of 8 to 11 Fr that can be inserted into the sheath 120 according to the thickness of the sheath 120 of 9 to 12 Fr, but is not limited thereto, and the thickness of the sheath 120 It is preferred that it is understood to have a corresponding diameter that can be inserted according to.
도 7은 본 발명의 일실시예에 따른 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기의 다른 일례의 구성을 나타내고 있다. 도 7에 도시된 바와 같이, 다른 일례의 하지정맥 혈전 제거기(100)는 시스(120)의 관이 분기된 형태의 이중 관으로, 분기된 상부 관으로는 혈전 제거 그물망(130)이 삽입되어 정맥의 혈전을 포집하도록 하고, 분기된 하부 관으로는 흡입 카테터(140)가 삽입되어 혈전 제거 그물망(130)에 의해 포집된 혈전을 흡인할 수 있도록 한다.7 is a block diagram illustrating another example of a lower extremity vein thrombus eliminator using a blood clot collection net and a blood clot suction catheter according to an embodiment of the present invention. As shown in FIG. 7, another example of the lower extremity vein thrombus remover 100 is a double tube in which the tube of the sheath 120 is branched, and a thrombus removal net 130 is inserted into the branched upper tube. The blood clots are collected, and the suction catheter 140 is inserted into the branched lower tube so that the blood clots collected by the clot removal net 130 can be sucked.
도 8은 본 발명의 일실시예에 따른 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기의 이용 방법의 흐름을 도시한 도면이고, 도 9 내지 도 12는 본 발명의 일실시예에 따른 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기의 이용 방법의 순서에 따른 혈전 제거 과정을 도시한 도면이다. 도 8에 도시된 바와 같이, 본 발명의 일실시예에 따른 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기의 이용 방법은, 가이드 와이어를 구비하는 안내유도관이 굵은 혈전으로 폐쇄된 정맥의 병변을 지나 정상적인 정맥까지 올라가서 거치되는 단계(S110), 시스가 안내유도관을 따라 유도되어 정맥의 혈전 제거를 위한 적정 혈관 위치에 거치되는 단계(S120), 카테터에 장착된 혈전 제거 그물망이 시스 내로 삽입되어 혈전을 지나 정상적인 혈관에서 펼쳐지는 단계(S130), 및 흡인 카테터가 혈전 제거 그물망에 포집된 혈전을 흡인하는 단계(S140)를 포함하여 구현될 수 있다.8 is a view showing a flow of a method of using a vein thrombus remover using a blood clot collection net and a thrombus suction catheter according to an embodiment of the present invention, and FIGS. 9 to 12 are diagrams according to an embodiment of the present invention. It is a diagram showing a blood clot removal process according to the sequence of a method of using a venous blood clot remover using a blood clot collection net and a clot suction catheter. As shown in FIG. 8, a method of using a lower extremity vein thrombus eliminator using a blood clot collection net and a thrombus suction catheter according to an embodiment of the present invention is a vein in which a guide guide tube having a guide wire is closed with a thick blood clot. The step of going up to the normal vein after passing the lesion of (S110), the step of being guided along the guide guide tube and placing the sheath at an appropriate blood vessel position for removing blood clots from the vein (S120), the thrombus removal net attached to the catheter is sheath It may be implemented including a step (S130) of being inserted into the blood clot and unfolding in a normal blood vessel (S130), and a step (S140) of aspirating the blood clot collected in the blood clot removal net by the suction catheter.
단계 S110에서는, 가이드 와이어(111)를 구비하는 안내유도관(110)이 굵은 혈전으로 폐쇄된 정맥의 병변을 지나 정상적인 정맥까지 올라가서 거치된다. 이러한 단계 S110에서의 안내유도관(110)은 도 9에 도시된 바와 같이, 시스(120)를 거치시킬 때 필요한 안내도관으로 기능한다. 여기서, 안내유도관(110)은 시스(120)가 정맥의 혈전 제거를 위한 적정 혈관 위치에 거치된 후에는 혈전 제거 그물망(130) 및 흡입 카테터(140)의 사용을 위해 제거될 수 있다.In step S110, the guide guide tube 110 provided with the guide wire 111 passes through the lesion of the vein closed by a thick thrombus and is mounted up to a normal vein. The guide guide pipe 110 in this step S110 functions as a guide pipe required when mounting the sheath 120, as shown in FIG. 9. Here, the guide guide tube 110 may be removed for use of the blood clot removal net 130 and the suction catheter 140 after the sheath 120 is mounted at an appropriate blood vessel position for removing blood clots from a vein.
단계 S120에서는, 단계 S110을 통해 가이드 와이어(111)를 구비하는 안내유도관(110)이 거치된 상태에서, 시스(120)가 안내유도관(110)을 따라 유도되어 정맥의 혈전 제거를 위한 적정 혈관 위치에 거치된다. 이러한 단계 S120에서의 시스(120)는 굵은 혈전으로 폐쇄된 정맥의 병변, 즉 정맥 혈전 제거를 위해 혈전 제거 그물망(130)과 흡입 카테터(140)의 사용이 가능하도록 하는 보호 피복관의 역할을 하며, 바람직하게는 굵은 정맥혈관 내에 거치될 수 있는 9 내지 12 Fr(French size)의 직경으로 구성될 수 있다.In step S120, in a state in which the guide guide tube 110 having the guide wire 111 is mounted through the step S110, the sheath 120 is guided along the guide guide tube 110 to remove blood clots in the vein. It is mounted in the blood vessel position. The sheath 120 in this step S120 serves as a protective sheath that enables the use of the clot removal net 130 and the suction catheter 140 to remove a lesion of a vein closed by a thick blood clot, that is, venous blood clot, Preferably, it may be configured with a diameter of 9 to 12 Fr (French size) that can be mounted in a thick vein vessel.
단계 S130에서는, 카테터(131)에 장착된 혈전 제거 그물망(130)이 시스(120) 내로 삽입되어 혈전을 지나 정상적인 혈관에서 펼쳐진다. 이러한 단계 S130에서의 혈전 제거 그물망(130)은 도 10 및 도 11에 각각 도시된 바와 같이, 가늘고 긴 형상의 유연성을 갖는 튜브로 이루어지는 카테터(131)의 내부에 거치되도록 장착된 상태에서, 정맥의 혈전을 지나 정상적인 혈관에서 펼쳐진 후 당겨 내려짐에 따라 혈전을 그물망 내에 포집하게 된다.In step S130, the blood clot removal net 130 mounted on the catheter 131 is inserted into the sheath 120 to pass through the blood clot and unfold in the normal blood vessel. The blood clot removal net 130 in this step S130 is mounted so as to be mounted inside the catheter 131 made of a flexible tube having an elongated shape, as shown in FIGS. 10 and 11, respectively, The blood clot is collected in the net as it passes through the clot and spreads out of the normal blood vessel and is pulled down.
또한, 혈전 제거 그물망(130)은 도 6에 도시된 바와 같이, 가늘고 긴 와이어의 일단으로 그물망이 타원형으로 펼쳐지는 구조로 구성되며, 혈전이 포집되는 후단 영역의 그물망이 더 조밀하게 형성될 수 있다.In addition, as shown in FIG. 6, the blood clot removal net 130 has a structure in which the net is spread in an oval shape with one end of a long thin wire, and the net in the rear end area where the clot is collected may be formed more densely. .
단계 S140에서는, 흡인 카테터(140)가 시스(120) 내로 삽입되어 혈전 제거 그물망(130)에 포집된 혈전을 흡인한다. 이러한 단계 S140에서의 흡인 카테터(140)는 도 12에 도시된 바와 같이, 가늘고 긴 형상의 유연성을 튜브의 말단에 형성된 복수의 측면공(141)을 통해 혈전 제거 그물망(130)에 포집된 혈전을 흡인하여 제거하게 된다.In step S140, the suction catheter 140 is inserted into the sheath 120 to suck the blood clots collected in the clot removal net 130. The suction catheter 140 in this step S140, as shown in Figure 12, the flexibility of the elongated shape through the plurality of side holes 141 formed at the end of the tube to remove the blood clots collected in the net 130 It is removed by suction.
또한, 흡인 카테터(140)는 도 5에 도시된 바와 같이, 가늘고 긴 형상의 유연성을 갖는 튜브로서, 혈전 제거 그물망(130)에 포집된 혈전을 흡인(aspiration)해 내는 복수의 측면공(141)이 형성되고, 복수의 측면공(141)이 형성되는 튜브의 말단이 약간 굽은 형태로 구성된다. 이러한 흡입 카테터(140)는 시스(120)의 굵기에 따라 시스(120)의 내경으로 들어갈 수 있는 직경의 크기를 갖는 8 내지 11 Fr(French size)의 직경으로 구성될 수 있다.In addition, the suction catheter 140 is a flexible tube having an elongated shape, as shown in FIG. 5, and a plurality of side holes 141 for aspiration of blood clots collected in the clot removal net 130 This is formed, and the end of the tube in which the plurality of side holes 141 are formed is configured in a slightly curved shape. The suction catheter 140 may have a diameter of 8 to 11 Fr (French size) having a size of a diameter that can enter the inner diameter of the sheath 120 depending on the thickness of the sheath 120.
상술한 바와 같이, 본 발명의 일실시예에 따른 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기 및 그 이용 방법은, 굵은 혈전으로 폐쇄된 정맥의 병변을 지나 정상적인 정맥까지 올라가서 거치되는 가이드 와이어를 구비하는 안내유도관과, 안내유도관을 따라 유도되어 정맥의 혈전 제거를 위한 적정 혈관 위치에 거치되는 시스와, 시스 내로 삽입되는 카테터에 장착되어 혈전을 지나 정상적인 혈관에서 펼쳐지는 혈전 제거 그물망과, 시스 내로 삽입되어 혈전 제거 그물망에 포집된 혈전을 흡인하는 흡입 카테터를 포함하여 구성함으로써, 시술자의 숙련도에 의존하지 않고도 굵은 혈전으로 폐쇄된 정맥의 혈전을 손쉽게 제거할 수 있도록 할 수 있으며, 혈전 제거 그물망과 흡입 카테터를 이용하여 정맥 혈전을 포집하고 흡인하여 제거할 수 있도록 함으로써, 굵기가 다양한 혈관에 적용이 가능하고, 특히 굽어져 있고 굴곡 있는 정맥에서 불필요한 출혈, 상부 색전, 혈관 손상, 혈전의 잔존, 및 혈액 소실의 최소화가 가능하도록 할 수 있게 된다.As described above, the lower extremity vein thrombus eliminator using a blood clot collection net and a thrombus suction catheter according to an embodiment of the present invention, and a method of using the same, is a guide that goes up to a normal vein through a lesion of a vein closed by a thick thrombus. A guide guide tube having a wire, a sheath guided along the guide guide tube and mounted at an appropriate blood vessel position for removal of blood clots from a vein, and a clot removal net that is installed on a catheter inserted into the sheath and spreads out from the normal blood vessel through the blood clot By including an inhalation catheter that is inserted into the sheath and sucks the blood clots collected in the clot removal net, it is possible to easily remove the clots in the veins closed by thick clots without depending on the skill of the operator. By collecting and aspirating venous thrombus using a removal net and a suction catheter, it can be applied to blood vessels of various thicknesses. In particular, unnecessary bleeding from curved and curved veins, upper embolism, blood vessel damage, blood clots It is possible to minimize residual and blood loss.
이상 설명한 본 발명은 본 발명이 속한 기술분야에서 통상의 지식을 가진 자에 의하여 다양한 변형이나 응용이 가능하며, 본 발명에 따른 기술적 사상의 범위는 아래의 특허청구범위에 의하여 정해져야 할 것이다.The present invention described above can be modified or applied in various ways by those of ordinary skill in the technical field to which the present invention belongs, and the scope of the technical idea according to the present invention should be determined by the following claims.

Claims (20)

  1. 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기(100)로서,As a lower extremity vein thrombus remover 100 using a blood clot collection net and a thrombus suction catheter,
    굵은 혈전으로 폐쇄된 정맥의 병변을 지나 정상적인 정맥까지 올라가서 거치되는 가이드 와이어(111)를 구비하는 안내유도관(introducer)(110);Introducer 110 having a guide wire 111 that is mounted by passing through a lesion of a vein closed by a thick blood clot to a normal vein;
    상기 안내유도관(110)을 따라 유도되어 정맥의 혈전 제거를 위한 적정 혈관 위치에 거치되는 시스(sheath)(120);A sheath 120 guided along the guide guide tube 110 and mounted at an appropriate blood vessel position for removing blood clots from a vein;
    상기 시스(120) 내로 삽입되는 카테터(131)에 장착되어 혈전을 지나 정상적인 혈관에서 펼쳐지는 혈전 제거 그물망(130); 및A thrombus removal net 130 which is mounted on the catheter 131 inserted into the sheath 120 and spreads through the thrombus in normal blood vessels; And
    상기 시스(120) 내로 삽입되어 상기 혈전 제거 그물망(130)에 포집된 혈전을 흡인하는 흡입 카테터(140)를 포함하는 것을 특징으로 하는, 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기.It characterized in that it comprises a suction catheter 140 that is inserted into the sheath 120 and sucks the blood clots collected in the clot removal net 130, a blood clot collecting net and a vein thrombus eliminator using a clot suction catheter.
  2. 제1항에 있어서, 상기 안내유도관(110)은,The method of claim 1, wherein the guide guide pipe (110),
    상기 시스(120)를 거치시킬 때 필요한 안내도관으로 기능하는 것을 특징으로 하는, 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기.A lower extremity vein thrombus eliminator using a mesh for collecting blood clots and a blood clot suction catheter, characterized in that it functions as a guide tube required when mounting the sheath 120.
  3. 제2항에 있어서, 상기 안내유도관(110)은,The method of claim 2, wherein the guide guide pipe (110),
    상기 시스(120)가 정맥의 혈전 제거를 위한 적정 혈관 위치에 거치된 후 제거되는 것을 특징으로 하는, 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기.The sheath 120 is removed after being mounted at an appropriate blood vessel position for removing blood clots from a vein, characterized in that the blood clot collecting net and a blood clot inhalation catheter used in the lower limb vein thrombus remover.
  4. 제1항에 있어서, 상기 시스(120)는,The method of claim 1, wherein the sheath (120),
    굵은 정맥혈관 내에 거치될 수 있는 9 내지 12 Fr(French size)의 직경으로 구성되는 것을 특징으로 하는, 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기.A lower extremity vein thrombus eliminator using a network for collecting thrombi and a thrombus suction catheter, characterized in that it consists of a diameter of 9 to 12 Fr (French size) that can be mounted in a thick vein vessel.
  5. 제1항 내지 제4항 중 어느 한 항에 있어서, 상기 혈전 제거 그물망(130)은,The method of any one of claims 1 to 4, wherein the blood clot removal net (130),
    가늘고 긴 형상의 유연성을 갖는 튜브로 이루어지는 카테터(131)의 내부에 거치되도록 장착된 상태에서, 정맥의 혈전을 지나 정상적인 혈관에서 펼쳐진 후 당겨 내려짐에 따라 혈전을 그물망 내에 포집하도록 기능하는 것을 특징으로 하는, 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기.In a state mounted to be mounted inside the catheter 131 made of a flexible tube having an elongated shape, it functions to collect the thrombus in the net as it is unfolded in the normal blood vessel and then pulled down through the blood clot in the vein. The lower extremity vein thrombus eliminator using a mesh for thrombus collection and a thrombus suction catheter.
  6. 제5항에 있어서, 상기 혈전 제거 그물망(130)은,The method of claim 5, wherein the blood clot removal net (130),
    가늘고 긴 와이어의 일단으로 그물망이 타원형으로 펼쳐지는 구조로 구성되는 것을 특징으로 하는, 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기.A vein thrombus eliminator using a network for collecting blood clots and a blood clot suction catheter, characterized in that the net is formed in an oval-shaped structure with one end of a long thin wire.
  7. 제6항에 있어서, 상기 혈전 제거 그물망(130)은,The method of claim 6, wherein the blood clot removal net (130),
    가늘고 긴 와이어의 일단으로 그물망이 타원형으로 펼쳐지는 구조를 갖되, 혈전이 포집되는 후단 영역의 그물망이 더 조밀하게 형성되는 것을 특징으로 하는, 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기.It has a structure in which the net is spread in an oval shape with one end of a long and thin wire, and the net of the rear end area where the blood clot is collected is formed more densely, a net for collecting blood clots and a blood clot remover using a blood clot suction catheter.
  8. 제5항에 있어서, 상기 흡입 카테터(140)는,The method of claim 5, wherein the suction catheter (140),
    가늘고 긴 형상의 유연성을 갖는 튜브로서, 상기 혈전 제거 그물망(130)에 포집된 혈전을 흡인(aspiration)해 내는 복수의 측면공(141)을 더 형성하는 것을 특징으로 하는, 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기.As a flexible tube having an elongated shape, characterized in that it further forms a plurality of side holes 141 for aspiration of blood clots collected in the clot removal net 130, a net for clot collection and a clot Leg vein thrombus eliminator using an inhalation catheter.
  9. 제8항에 있어서, 상기 흡입 카테터(140)는,The method of claim 8, wherein the suction catheter (140),
    상기 혈전 제거 그물망(130)에 포집된 혈전을 흡인(aspiration)해 내는 복수의 측면공(141)을 더 형성하는 가늘고 긴 형상의 유연성을 갖는 튜브 형상으로 말단이 약간 굽은 형태로 구성되는 것을 특징으로 하는, 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기.It is characterized in that it is configured in a shape having a flexible tube shape of an elongated shape that further forms a plurality of side holes 141 for aspiration of the blood clots collected in the blood clot removal net 130, and the end is slightly bent. The lower extremity vein thrombus eliminator using a mesh for thrombus collection and a thrombus suction catheter.
  10. 제9항에 있어서, 상기 흡입 카테터(140)는,The method of claim 9, wherein the suction catheter (140),
    상기 시스(120)의 굵기에 따라 시스(120)의 내경으로 들어갈 수 있는 직경의 크기를 갖되, 8 내지 11 Fr(French size)의 직경으로 구성되는 것을 특징으로 하는, 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기.Depending on the thickness of the sheath 120, it has a size of a diameter that can fit into the inner diameter of the sheath 120, but is configured with a diameter of 8 to 11 Fr (French size), a net for collecting blood clots and a blood clot suction Leg vein thrombus eliminator using a catheter.
  11. 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기(100)의 이용 방법으로서,As a method of using the vein thrombus remover 100 using a blood clot collection net and a blood clot suction catheter,
    (1) 가이드 와이어(111)를 구비하는 안내유도관(110)이 굵은 혈전으로 폐쇄된 정맥의 병변을 지나 정상적인 정맥까지 올라가서 거치되는 단계;(1) step in which the guide guide tube 110 provided with the guide wire 111 goes up to the normal vein through the lesion of the vein closed by a thick blood clot and is mounted;
    (2) 상기 단계 (1)을 통해 가이드 와이어(111)를 구비하는 안내유도관(110)이 거치된 상태에서, 시스(120)가 상기 안내유도관(110)을 따라 유도되어 정맥의 혈전 제거를 위한 적정 혈관 위치에 거치되는 단계;(2) Through the step (1), in a state in which the guide guide tube 110 having the guide wire 111 is mounted, the sheath 120 is guided along the guide guide tube 110 to remove blood clots in the vein. Being mounted at an appropriate blood vessel position for;
    (3) 카테터(131)에 장착된 혈전 제거 그물망(130)이 상기 시스(120) 내로 삽입되어 혈전을 지나 정상적인 혈관에서 펼쳐지는 단계; 및(3) the thrombus removal net 130 mounted on the catheter 131 is inserted into the sheath 120 to pass through the thrombus and spread out in a normal blood vessel; And
    (4) 흡인 카테터(140)가 상기 시스(120) 내로 삽입되어 상기 혈전 제거 그물망(130)에 포집된 혈전을 흡인하는 단계를 포함하는 것을 특징으로 하는, 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기의 이용 방법.(4) A suction catheter 140 is inserted into the sheath 120 to aspirate the thrombus collected in the thrombus removal net 130, characterized in that How to use a vein thrombus eliminator.
  12. 제1항에 있어서, 상기 안내유도관(110)은,The method of claim 1, wherein the guide guide pipe (110),
    상기 시스(120)를 거치시킬 때 필요한 안내도관으로 기능하는 것을 특징으로 하는, 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기의 이용 방법.A method of using a vein thrombus eliminator using a blood clot collection net and a blood clot suction catheter, characterized in that it functions as a guide tube required when mounting the sheath 120.
  13. 제12항에 있어서, 상기 안내유도관(110)은,The method of claim 12, wherein the guide guide pipe (110),
    상기 시스(120)가 정맥의 혈전 제거를 위한 적정 혈관 위치에 거치된 후 제거되는 것을 특징으로 하는, 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기의 이용 방법.The method of using a lower limb vein thrombus remover using a mesh for collecting thrombi and a thrombus suction catheter, characterized in that the sheath 120 is removed after being mounted at an appropriate blood vessel position for removing blood clots from a vein.
  14. 제11항에 있어서, 상기 시스(120)는,The method of claim 11, wherein the sheath (120),
    굵은 정맥혈관 내에 거치될 수 있는 9 내지 12 Fr(French size)의 직경으로 구성되는 것을 특징으로 하는, 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기의 이용 방법.A method of using a vein thrombus eliminator using a blood clot collection net and a blood clot suction catheter, characterized in that consisting of a diameter of 9 to 12 Fr (French size) that can be mounted in a thick vein vessel.
  15. 제11항 내지 제14항 중 어느 한 항에 있어서, 상기 혈전 제거 그물망(130)은,The method of any one of claims 11 to 14, wherein the blood clot removal net (130),
    가늘고 긴 형상의 유연성을 갖는 튜브로 이루어지는 카테터(131)의 내부에 거치되도록 장착된 상태에서, 정맥의 혈전을 지나 정상적인 혈관에서 펼쳐진 후 당겨 내려짐에 따라 혈전을 그물망 내에 포집하도록 기능하는 것을 특징으로 하는, 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기의 이용 방법.In a state mounted to be mounted inside the catheter 131 made of a flexible tube having an elongated shape, it functions to collect the thrombus in the net as it is unfolded in the normal blood vessel and then pulled down through the blood clot in the vein. How to use a vein thrombus eliminator using a blood clot collection net and a thrombus suction catheter.
  16. 제15항에 있어서, 상기 혈전 제거 그물망(130)은,The method of claim 15, wherein the blood clot removal net (130),
    가늘고 긴 와이어의 일단으로 그물망이 타원형으로 펼쳐지는 구조로 구성되는 것을 특징으로 하는, 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기의 이용 방법.A method of using a vein thrombus eliminator using a mesh for collecting blood clots and a blood clot suction catheter, characterized in that the net is formed in an oval-shaped structure with one end of a long thin wire.
  17. 제16항에 있어서, 상기 혈전 제거 그물망(130)은,The method of claim 16, wherein the blood clot removal net (130),
    가늘고 긴 와이어의 일단으로 그물망이 타원형으로 펼쳐지는 구조를 갖되, 혈전이 포집되는 후단 영역의 그물망이 더 조밀하게 형성되는 것을 특징으로 하는, 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기의 이용 방법.It has a structure in which the net is spread out in an oval shape with one end of a long thin wire, and the net in the rear end area where the clot is collected is formed more densely. How to use.
  18. 제15항에 있어서, 상기 흡입 카테터(140)는,The method of claim 15, wherein the suction catheter (140),
    가늘고 긴 형상의 유연성을 갖는 튜브로서, 상기 혈전 제거 그물망(130)에 포집된 혈전을 흡인(aspiration)해 내는 복수의 측면공(141)을 더 형성하는 것을 특징으로 하는, 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기의 이용 방법.As a flexible tube having an elongated shape, characterized in that it further forms a plurality of side holes 141 for aspiration of blood clots collected in the clot removal net 130, a net for clot collection and a clot How to use a vein thrombus eliminator using an inhalation catheter.
  19. 제18항에 있어서, 상기 흡입 카테터(140)는,The method of claim 18, wherein the suction catheter (140),
    상기 혈전 제거 그물망(130)에 포집된 혈전을 흡인(aspiration)해 내는 복수의 측면공(141)을 더 형성하는 가늘고 긴 형상의 유연성을 갖는 튜브 형상으로 말단이 약간 굽은 형태로 구성되는 것을 특징으로 하는, 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기의 이용 방법.It is characterized in that it is configured in a shape having a flexible tube shape of an elongated shape that further forms a plurality of side holes 141 for aspiration of the blood clots collected in the blood clot removal net 130, and the end is slightly bent. How to use a vein thrombus eliminator using a blood clot collection net and a thrombus suction catheter.
  20. 제19항에 있어서, 상기 흡입 카테터(140)는,The method of claim 19, wherein the suction catheter (140),
    상기 시스(120)의 굵기에 따라 시스(120)의 내경으로 들어갈 수 있는 직경의 크기를 갖되, 8 내지 11 Fr(French size)의 직경으로 구성되는 것을 특징으로 하는, 혈전 포집용 그물망과 혈전 흡입 카테터를 이용한 하지정맥 혈전 제거기의 이용 방법.Depending on the thickness of the sheath 120, it has a size of a diameter that can fit into the inner diameter of the sheath 120, but is configured with a diameter of 8 to 11 Fr (French size), a net for collecting blood clots and a blood clot suction How to use a lower extremity vein thrombus eliminator using a catheter.
PCT/KR2020/010286 2019-08-05 2020-08-04 Device for removing thrombi in varicose vein using thrombus collecting mesh and thrombus suction catheter, and method for using same WO2021025440A2 (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113208770A (en) * 2021-04-12 2021-08-06 聚辉医疗科技(深圳)有限公司 Conveying device

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8430837B2 (en) * 2007-02-05 2013-04-30 Boston Scientific Scimed, Inc. Thrombectomy apparatus and method
US8771289B2 (en) * 2009-12-21 2014-07-08 Acist Medical Systems, Inc. Thrombus removal device and system
JP5783637B2 (en) * 2012-11-28 2015-09-24 朝日インテック株式会社 Suction catheter and suction catheter assembly
KR20160046215A (en) * 2014-10-20 2016-04-28 가톨릭관동대학교산학협력단 Catheter assembly
KR102115426B1 (en) * 2017-12-08 2020-05-26 (주) 타우피엔유메디칼 Catch Catheter

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113208770A (en) * 2021-04-12 2021-08-06 聚辉医疗科技(深圳)有限公司 Conveying device
CN113208770B (en) * 2021-04-12 2021-11-16 聚辉医疗科技(深圳)有限公司 Conveying device
CN113827369A (en) * 2021-04-12 2021-12-24 聚辉医疗科技(深圳)有限公司 Conveying device

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