WO2021000256A1

WO2021000256A1 - Aqueous humor collection device

Info

Publication number: WO2021000256A1
Application number: PCT/CN2019/094384
Authority: WO
Inventors: 赵潺
Original assignee: 北京华视诺维医疗科技有限公司
Priority date: 2019-07-02
Filing date: 2019-07-02
Publication date: 2021-01-07

Abstract

An aqueous humor collection device (100), comprising: an outer cylinder (1) provided with a puncture needle (2) mounting end and a liquid collecting pipe (31) mounting end; a puncture needle (2) inserted in the puncture needle (2) mounting end and comprising a puncture needle (2) outer end and a puncture needle (2) inner end; and a liquid collecting pipe assembly (3) pluggably and movably inserted in an outer cylinder (1) cavity and comprising a liquid collecting pipe (31) and a pipe stopper (33), wherein a ventilation structure is formed between the liquid collecting pipe assembly (3) and the inner peripheral wall of the outer cylinder (1), and can be communicated with a cylinder cavity area, between the puncture needle (2) inner end and the pipe stopper (33), of the outer cylinder (1) cavity. The aqueous humor collection device (100) also comprises a limiting buffer structure used for limiting radial displacement of the liquid collecting pipe assembly (3) and forming contact damping between the liquid collecting pipe assembly (3) and the inner peripheral wall of the outer cylinder (1). The aqueous humor collection device (100) can control the drainage speed of aqueous humor during puncture, avoid the contamination of the aqueous humor after collection is completed and the waste caused by transfer of the aqueous humor, and can ensure the insertion and pulling stability of the liquid collecting pipe assembly (3), thereby facilitating improving the safety, reliability and detection accuracy.

Description

Aqueous water collection device

Technical field

The invention relates to the technical field of medical appliances, in particular to an aqueous humor collection device.

Background technique

Anterior chamber puncture of the eye is a medical technology that pierces the cornea of the eye to make the aqueous humor flow out. It has important application value in ophthalmology clinical research work. It is mainly used to reduce intraocular pressure, aqueous humor collection and other therapeutic pretreatments. Room discharge.

At present, there is no unified special equipment and consumables for the implementation of anterior chamber puncture. In actual clinical work, 1ml syringe needles are often used as anterior chamber puncture needles. But in the process of puncturing with the 1ml syringe needle, the drainage speed of aqueous humor is difficult to control. When the fluid is discharged too fast, it will cause a rapid drop in intraocular pressure, and even more serious complications may even cause other complications. In addition, since the aqueous humor in the syringe cavity is further transferred to the microcentrifuge tube after the aqueous humor is collected, the aqueous humor will be wasted during this process, and the aqueous humor will be affected by the external environment during the transfer process. Risk of contamination due to contact, resulting in deviations in test results and poor reliability.

It can be seen that there is an urgent need to develop a new collection device that can solve the problems of poor safety and reliability during the anterior chamber puncture.

Summary of the invention

In view of the above-mentioned defects or deficiencies of the prior art, the present invention provides an aqueous humor collection device that can control the drainage speed of aqueous humor during the puncture process, and can avoid contamination of the aqueous humor after collection and waste due to transfer , In order to improve safety, reliability and detection accuracy.

In order to achieve the above objective, the present invention provides an aqueous humor collection device, which includes:

The outer cylinder is provided with a puncture needle installation end and a liquid collection tube installation end;

A puncture needle inserted in the puncture needle installation end and includes an outer end of the puncture needle and an inner end of the puncture needle that extends into the cavity of the outer cylinder;

The liquid sampling tube assembly is pluggable and movably inserted from the installation end of the liquid sampling tube into the barrel cavity of the outer cylinder and includes a liquid sampling tube and a liquid sampling tube for sealing in the barrel cavity of the outer cylinder The pipe plug of the nozzle;

Wherein, a ventilation structure is formed between the liquid sampling tube assembly and the inner peripheral wall of the outer cylinder, and the ventilation structure communicates with the cylinder cavity area of the outer cylinder cavity between the inner end of the puncture needle and the tube plug, The aqueous humor collection device further includes a limiting buffer structure for limiting the displacement of the sampling tube assembly in the radial direction and for forming contact damping between the sampling tube assembly and the inner peripheral wall of the outer cylinder.

Optionally, the limiting buffer structure includes a limiting protrusion protruding from the outer peripheral wall of the sampling tube assembly or from the inner peripheral wall of the outer cylinder, and the radial ends of the limiting protrusion are respectively connected to the The outer peripheral wall of the liquid sampling tube assembly and the inner peripheral wall of the outer cylinder.

Optionally, the limiting buffer structure includes the limiting protrusions arranged at intervals along the tube length direction of the sampling tube assembly or continuously extending along the tube length direction, and the limiting protrusions are arranged along the length of the tube. The total span of the tube length direction is not less than half of the length of the liquid sampling tube.

Optionally, the limiting protrusion is integrally formed on the outer peripheral wall of the liquid sampling tube; or, the liquid sampling tube assembly includes a tube set sheathed on the outer peripheral wall of the liquid sampling tube, and the limiting protrusion The position protrusion is arranged on the outer peripheral wall of the tube set.

Optionally, the tube set is an elastic tube set.

Optionally, the limiting and buffering structure includes a plurality of limiting protrusions arranged at intervals in a circumferential direction, and gaps between the plurality of limiting protrusions are formed as the ventilation structure;

Alternatively, the limiting buffer structure includes the limiting protrusion formed continuously extending in the circumferential direction, between the limiting protrusion and the outer peripheral wall of the liquid sampling tube assembly or between the limiting protrusion and the A vent gap as the ventilation structure is formed between the inner peripheral wall of the outer cylinder.

Optionally, a plurality of the limiting protrusions arranged at intervals along the circumferential direction are all convex points.

Optionally, the limiting protrusion formed continuously extending in the circumferential direction is in a corrugated shape or an oblique tooth shape.

Optionally, the liquid sampling tube assembly further includes a supporting tube frame for fixing the liquid sampling tube, and the limiting buffer structure is formed between the outer peripheral wall of the supporting tube frame and the inner peripheral wall of the outer cylinder .

Optionally, the liquid sampling tube and the supporting tube frame are fixed by screw connection or snap connection.

In the present invention, since the aqueous humor collection device is provided with a limit buffer structure, it can limit its displacement in the radial direction during the process of plugging and unplugging the liquid sampling tube assembly, that is, to ensure that the liquid sampling tube assembly only moves in the axial direction and can A certain movement damping is generated to prevent the insertion and extraction speed from being too fast, so it can not only ensure that the inner end of the puncture needle accurately pierces the tube plug to be inserted into the lumen of the liquid collection tube, but also ensures that it can be pulled out stably after the aqueous humor is collected Liquid collection tube assembly to avoid leakage of aqueous humor in the lumen and greatly improve reliability. In addition, the liquid sampling tube assembly is provided with a tube plug so that the lumen of the liquid sampling tube is in a negative pressure state. When the inner end of the puncture needle pierces the tube plug to drain the aqueous humor into the liquid sampling tube lumen, it follows The amount of fluid gradually increases, and the difference between the pressure in the lumen and the pressure in the anterior chamber gradually decreases, so the drainage speed of aqueous humor is gradually reduced, thereby avoiding the dangerous situation of sudden drop in intraocular pressure and greatly improving safety. Furthermore, after the collection is completed, since the liquid sampling tube assembly can be pulled out from the outer cylinder cavity as a whole, and the aqueous humor in the liquid sampling tube can be detected directly, no further transfer is required, so it can avoid the The aqueous humor contacts the external environment to ensure the purity of the collected aqueous humor, thereby improving the accuracy of subsequent testing.

Other features and advantages of the present invention will be described in detail in the following specific embodiments.

Description of the drawings

The accompanying drawings are used to provide a further understanding of the present invention and constitute a part of the specification. Together with the following specific embodiments, they are used to explain the present invention, but do not constitute a limitation to the present invention. In the attached picture:

Figure 1 is a perspective view of an aqueous humor collection device in a specific embodiment of the present invention;

Figure 2 is a front view of the aqueous humor collection device in Figure 1;

3 is a main cross-sectional view of the aqueous humor collection device in FIG. 2 when the puncture needle does not pierce the tube plug;

Figure 4 is a main cross-sectional view of the aqueous humor collection device in Figure 3 when a puncture-proof partition is provided;

Figure 5 is a cross-sectional view of the aqueous humor collection device in Figure 1;

Fig. 6 is a schematic structural diagram of the puncture needle of the aqueous humor collection device in Fig. 3 when a peripheral wall water outlet hole is provided;

Fig. 7 is a schematic structural view of the pipe plug of the aqueous humor collection device in Fig. 3 provided with an open peripheral wall and semicircular pipe plug exhaust channel;

Fig. 8 is a schematic structural view of the pipe plug of the aqueous humor collection device in Fig. 3 provided with an open peripheral wall and a semi-rectangular pipe plug exhaust channel;

Fig. 9 is a schematic structural diagram of the pipe plug of the aqueous humor collection device in Fig. 3 when a peripheral wall closed and circular pipe plug exhaust channel is provided;

Fig. 10 is a schematic structural diagram of the pipe plug of the aqueous humor collection device in Fig. 3 when a peripheral wall closed and arc-shaped pipe plug exhaust channel is provided;

11 is a schematic structural diagram of the liquid collection tube and the supporting tube frame of the aqueous humor collection device in FIG. 3 when connected by a buckle;

12 is a schematic structural diagram of the liquid collection tube of the aqueous humor collection device in the specific embodiment of the present invention when a convex point-like limiting protrusion is integrally formed;

13 is a schematic diagram of the structure of the liquid collection tube of the aqueous humor collection device in the specific embodiment of the present invention when a corrugated limiting protrusion is integrally formed;

14 is a schematic structural view of the liquid collection tube of the aqueous humor collection device in the specific embodiment of the present invention when the tube kit is sheathed and the limiting protrusion is in the shape of a convex point;

15 is a schematic structural diagram of the liquid collection tube of the aqueous humor collection device in the specific embodiment of the present invention when the tube kit is sheathed and the limiting protrusion is corrugated;

16 is a schematic structural view of the liquid collection tube of the aqueous humor collection device in the specific embodiment of the present invention when the tube kit is sheathed and the limiting protrusion is in the shape of a helical tooth;

FIG. 17 is a schematic structural diagram of the supporting pipe frame of the aqueous humor collection device in the specific embodiment of the present invention when a convex point-like limiting protrusion is integrally formed;

18 is a schematic structural diagram of the supporting pipe frame of the aqueous humor collection device in the specific embodiment of the present invention when a corrugated limiting protrusion is integrally formed;

19 is a schematic diagram of the structure of the supporting tube frame of the aqueous humor collection device in the specific embodiment of the present invention when the oblique tooth-shaped limiting protrusion is integrally formed;

20 is a schematic structural diagram of the supporting tube frame of the aqueous humor collection device in the specific embodiment of the present invention when the tube kit is sheathed and the limiting protrusion is in the shape of a convex point;

21 is a schematic structural diagram of the supporting tube frame of the aqueous humor collection device in the specific embodiment of the present invention when the tube kit is sheathed and the limiting protrusion is corrugated;

22 is a schematic diagram of the structure of the supporting tube frame of the aqueous humor collection device in the specific embodiment of the present invention when the tube kit is sheathed and the limiting protrusion is in the shape of an oblique tooth.

Description of reference signs:

100 Aqueous Water Collection Device

1 Outer cylinder body 2 puncture needles

3 Liquid collection tube assembly 4 Needle holder

5 Anti-puncture spacers 6 6 Limiting protrusions

7 Needle caps 8 soft sleeves

11 Separator insertion slot 21 21 Water outlet hole on the wall

22 Axial water outlet hole 31 Liquid sampling pipe

32 Supporting pipe frame 33 Pipe plugging

34 Pipe kit 35 Annular groove

36 Groove vents 37 Ring limiters

311 Sampling pipe card slot 321 Pipe rack snap

322 Pipe rack snap button 331 Pipe plug exhaust channel

332 Piercing the blind guide hole

Detailed ways

The specific embodiments of the present invention will be described in detail below with reference to the accompanying drawings. It should be understood that the specific embodiments described here are only used to illustrate and explain the present invention, but not to limit the present invention.

The aqueous humor collection device according to the present invention will be described below with reference to the drawings.

As shown in FIGS. 1 to 16, an exemplary embodiment of the present invention provides an aqueous humor collection device 100, which includes an outer cylinder 1, a puncture needle 2, and a collection tube assembly 3. The outer cylinder 1 is provided with a puncture needle installation end and a liquid sampling tube installation end at both ends in the axial direction. The puncture needle 2 is fixedly installed at the installation end of the puncture needle and is provided with an inner end of the puncture needle located in the cavity of the outer cylinder and an outer end of the puncture needle located outside the cavity of the outer cylinder. The sampling tube assembly 3 includes a sampling tube 31 that is inserted from the installation end of the sampling tube into the barrel cavity of the outer cylinder and can be inserted and removed in the axial direction, and is arranged in the outer cylinder cavity for sealing the nozzle of the sampling tube. The pipe plug 33. Among them, the static friction coefficient between the tube plug 33 and the inner peripheral wall of the outer cylinder is μ1, and the static friction coefficient between the tube plug 33 and the nozzle of the liquid collection tube is μ2, and satisfies: μ1<μ2. Alternatively, the pipe plug 33 may be spaced apart from the inner peripheral wall of the outer cylinder to ensure that the pipe plug 33 and the inner peripheral wall of the outer cylinder do not contact each other.

When the aqueous humor collection device 100 in the exemplary embodiment of the present invention is used for anterior chamber puncture, the fluid collection tube assembly 3 can be moved toward the inner end of the puncture needle, so that the inner end of the puncture needle pierces the soft sleeve 8 and the tube plug 33 Then, it is inserted into the lumen of the liquid collection tube to drain the aqueous humor in the anterior chamber to the lumen of the liquid collection tube through the outer end of the puncture needle and the inner end of the puncture needle. During this collection process, because the nozzle of the liquid sampling tube is sealed by the tube plug 33, the lumen of the liquid sampling tube is always in a negative pressure state, but as the amount of liquid in the lumen gradually increases, the pressure in the lumen and the pressure in the anterior chamber The difference is gradually reduced, so the drainage speed of aqueous humor will gradually decrease, so as to avoid the dangerous situation of sudden drop in intraocular pressure, and greatly improve the safety of puncture drainage.

Further, when the aqueous humor is collected, the sampling tube assembly 3 can be pulled out from the outer cylinder cavity as a whole, and then the sampling tube 31 can be directly placed in a specific detection instrument for specific item detection, which is consistent with the prior art In contrast, there is no need to further transfer the collected aqueous humor, so the aqueous humor in the lumen of the liquid collection tube can be prevented from contacting the external environment, and the purity of the collected aqueous humor can be ensured, thereby improving the accuracy and reliability of subsequent testing It can avoid the waste caused by transferring aqueous humor.

In addition, because it is defined that the static friction coefficient μ1 between the pipe plug 33 and the inner peripheral wall of the outer cylinder is smaller than the static friction coefficient between the pipe plug 33 and the nozzle of the liquid sampling tube, which is μ2, or the pipe plug 33 is spaced from the inner peripheral wall of the outer cylinder The setting can ensure that when the liquid sampling tube assembly 3 is pulled out from the outer cylinder cavity as a whole, the tube plug 33 will always tightly block the liquid sampling tube nozzle, thereby more reliably ensuring the purity of the collected aqueous humor .

In some embodiments, when the pipe plug 33 and the inner peripheral wall of the outer cylinder are in contact with each other, in order to better prevent the pipe plug 33 from falling off, the pipe plug 33 and the inner peripheral wall of the outer cylinder are preferably arranged in contact with each other through a smooth surface. For example, the radially outer end surface of the pipe plug 33 or the inner peripheral wall surface of the outer cylinder can be set as a smooth surface, or the radial outer end surface of the pipe plug 33 and the inner peripheral wall surface of the outer cylinder can be set as smooth surfaces at the same time.

In some embodiments, the aqueous humor collection device 100 further includes an anti-sloshing structure for limiting the displacement of the sampling tube assembly 3 along the radial direction of the outer cylinder cavity, and an anti-sloshing structure for limiting the displacement between the sampling tube assembly 3 and the inner peripheral wall of the outer cylinder. A plug-in buffer structure with contact damping is formed between. The anti-sloshing structure can ensure that the liquid sampling tube assembly 3 only moves in the axial direction during the insertion and removal process without radial sloshing. It can not only ensure that the inner end of the puncture needle accurately pierces the tube plug 33 during the puncture process to insert it In the lumen of the liquid collection tube, it can be ensured that the liquid collection tube assembly 3 can be pulled out stably after the aqueous humor collection is completed, so as to avoid the leakage of aqueous humor in the liquid collection tube lumen, thereby further improving the accuracy and reliability of subsequent detection . The plugging buffer structure can prevent the plugging speed of the liquid sampling tube assembly 3 from being too fast, and can also improve the plugging stability of the liquid sampling tube assembly 3.

As shown in FIGS. 3 and 4, the anti-sloshing structure may include an annular groove 35 formed on the outer peripheral wall of the liquid sampling tube assembly 3 and an annular stopper 37 provided in the hoop annular groove 35. The annular stopper 37 The radially outer end of 37 abuts against the inner peripheral wall of the outer cylinder. It should be noted that, in addition to preventing the radial sloshing of the liquid sampling tube assembly 3, the annular stopper 37 can make the inner end of the puncture needle pierce the tube plug 33 more accurately and prevent deviation during the puncture process. Increase the plugging resistance of the sampling tube assembly 3, so that the operator can feel a certain pushing feel, so as to avoid the inaccurate puncture caused by the too fast moving speed when the sampling tube assembly 3 is pushed toward the inner end of the puncture needle In order to prevent the inner end of the puncture needle from being inserted into the lumen of the liquid collection tube, the stability and reliability of the puncture drainage process are effectively improved. In addition, the liquid sampling tube assembly 3 can be prevented from being separated from the outer cylinder when the aqueous humor collection device 100 is taken, thereby improving the reliability of the product. Preferably, multiple sets of annular grooves 35 and corresponding annular stoppers 37 can be provided to obtain better effects.

In order to reduce production difficulty and cost, the annular limiter 37 can be preferably set as an easy-to-obtain, inexpensive and good-quality rubber band or other elastic ring, and the annular limiter 37 made of elastic material and the inner peripheral wall of the outer cylinder The formation of elastic contact between them can avoid excessive friction and abrasion of the inner peripheral wall of the outer cylinder.

Further, a groove vent 36 penetrating along the axial direction of the outer cylinder cavity can be formed on the groove side wall of the annular groove 35, so that the outer cylinder cavity is between the pipe plug 33 and the puncture needle installation end. The area of the barrel cavity can be communicated with the atmosphere through the groove vent 36, so as to avoid the formation of an air plug in the barrel cavity of the outer cylinder and affect the smooth plugging and unplugging of the liquid collection tube assembly 3, thereby improving the reliability of the use of the aqueous humor collection device 100 Sex.

As shown in Figures 12 to 16, the anti-sloshing structure may also include a limiting protrusion 6 protruding from the outer peripheral wall of the liquid sampling tube assembly 3 or from the inner peripheral wall of the outer cylinder, and radial ends of the limiting protrusion 6 The outer circumferential wall of the liquid sampling tube assembly 3 and the inner circumferential wall of the outer cylinder are respectively connected to prevent the liquid sampling tube assembly 3 from sloshing radially. In addition, the limiting protrusion 6 also has the function of a plug-in buffer structure, that is, the limiting protrusion 6 is formed as a limiting buffer structure with a simplified structure.

When the limiting protrusion 6 is provided on the outer peripheral wall of the liquid sampling tube assembly 3, the limiting protrusion 6 can be integrally formed on the outer peripheral wall of the liquid sampling tube 31. Alternatively, a tube set 34 sheathed on the outer peripheral wall of the liquid sampling tube 31 can be provided in the sampling tube assembly 3, and the limiting protrusion 6 can be provided on the outer peripheral wall of the tube set 34, because the tube set 34 is detachable Therefore, it can be reused, and it is relatively less difficult to form the limiting protrusion 6 on the tube sleeve 34, which is more conducive to reducing production costs.

Further, the tube set 34 can be set as an elastic tube set to prevent the liquid sampling tube 31 from rupturing due to rigid contact when subjected to a radial restriction, thereby reducing the risk of aqueous humor leakage.

In some embodiments, the anti-sloshing structure may include a plurality of limiting protrusions 6 arranged at intervals in the circumferential direction to ensure that the liquid sampling tube 31 is coaxially arranged with the outer cylinder cavity, thereby ensuring that the liquid sampling tube 31 is arranged along the Axial smooth plug-in movement. In addition, since a vent gap is formed between the plurality of spacing protrusions 6 spaced apart, the barrel cavity of the outer cylinder body between the puncture needle installation end and the pipe plug 33 can communicate with the atmosphere through the vent gap , Thereby avoiding the formation of a gas plug in the cavity of the outer cylinder and affecting the smooth insertion and removal of the liquid sampling tube assembly 3. For example, referring to FIGS. 12 and 14, a plurality of limiting protrusions 6 arranged at intervals along the circumferential direction may be arranged in a convex point shape.

Alternatively, in some embodiments, the limiting protrusion 6 may also be continuously extended in the circumferential direction. When the limiting protrusion 6 is formed on the inner peripheral wall of the outer cylinder, an exhaust gap is preferably formed between the limiting protrusion 6 and the outer peripheral wall of the liquid sampling tube assembly 3 to avoid the formation of a gas plug. When the limiting protrusion 6 is formed on the outer peripheral wall of the liquid sampling tube assembly 3, an exhaust gap is also preferably formed between the limiting protrusion 6 and the inner peripheral wall of the outer cylinder. For example, referring to FIGS. 13, 15 and 16, the limiting protrusions 6 continuously extending in the circumferential direction may be arranged in a corrugated shape or a helical tooth shape.

It can be seen that a ventilation structure can be formed in the limit buffer structure at the same time, so as to further simplify the structure of the aqueous humor collection device 100.

In order to further improve the plugging and unplugging stability of the liquid sampling tube assembly 3, no matter whether the limiting protrusions 6 are arranged at intervals along the tube length direction of the liquid sampling tube assembly 3, or are continuously extended and formed along the tube length direction, it is preferable to limit the protrusions 6 The total span of the position protrusion 6 along the length of the tube is set to be not less than half of the length of the liquid sampling tube. In other words, when the number of limiting protrusions 6 arranged along the length of the tube is large enough, the formation of a lever fulcrum on the outer peripheral wall of the sampling tube assembly 3 can be avoided, thereby more reliably preventing the sampling tube assembly 3 from shaking in the radial direction. .

In some embodiments, the liquid sampling tube assembly 3 further includes a supporting tube frame 32 for fixing the liquid sampling tube 31. Under this structure, the anti-sloshing structure can be arranged between the outer peripheral wall of the support pipe frame 32 and the inner peripheral wall of the outer cylinder, for example, as shown in FIGS. 17 to 22. The supporting tube frame 32 can better improve the stability of the liquid sampling tube assembly 3 and reduce the risk of the liquid sampling tube assembly 3 being broken due to collision or pressing.

Since the liquid sampling tube needs to be taken out separately after the aqueous humor is collected, the connection method between the liquid sampling tube 31 and the support tube frame 32 must meet the requirements of stability and quick disassembly. Preferably, the liquid sampling tube 31 and the support tube frame 32 can be fixed by screw connection or snap connection.

For example, referring to FIG. 11, the sampling tube 31 and the supporting tube frame 32 are connected by a snap. When the sampling tube 31 needs to be inserted into the supporting tube frame 32, the sampling tube 31 is pushed to the right until the tube The rack buckle 321 is clamped into the liquid collection tube clamping groove 311, so that the liquid collection tube 31 and the supporting tube rack 32 can be locked and locked with each other. When the liquid sampling tube 31 needs to be taken out, the tube rack buckle button 322 can be pressed to lift the tube rack buckle 321 to escape the liquid sampling tube clamping groove 311, and the liquid sampling tube 31 can be quickly taken out from the supporting tube rack 32.

In some embodiments, the aqueous humor collection device 100 further includes a needle holder 4 for fixing the puncture needle 2. Among them, the outer end of the puncture needle protrudes from the outer end of the needle holder and the inner end of the puncture needle protrudes from the inner end of the needle holder, and a quick plug-in connection is formed between the inner end of the needle holder and the installation end of the puncture needle, which helps reduce the difficulty of installation. Thereby improving assembly efficiency. For example, a threaded connection or a snap-fit connection can be formed between the inner end of the needle holder and the puncture needle installation end.

In some embodiments, the aqueous humor collection device 100 further includes an anti-puncture spacer 5, which is used to isolate the inner end of the puncture needle and the tube plug 33 from each other along the axial direction of the outer cylinder cavity. This prevents the inner end of the puncture needle from piercing the tube plug 33 when the aqueous humor collection device 100 is not used for anterior chamber puncture, which effectively prevents the device from failing before being used. For example, in the case of transportation or misoperation by medical personnel, the puncture-proof partition 5 can prevent the aqueous humor collection device 100 from failing. Of course, in order not to affect the normal puncture and drainage of the aqueous humor collection device 100, the anti-puncture spacer 5 is set as a detachable piece, and the anti-puncture spacer 5 can be removed before the puncture.

For example, referring to FIG. 4, a spacer inserting groove 11 can be provided on the peripheral wall of the outer cylinder 1, and the spacer inserting groove 11 and the outer cylinder cavity are in the cylindrical cavity between the inner end of the puncture needle and the pipe plug 33. The areas communicate with each other, and the anti-puncture spacer 5 can be inserted into the barrel cavity area through the spacer insertion slot 11, and placed between the inner end of the puncture needle and the tube plug 33, thereby connecting the inner end of the puncture needle and the tube plug 33 33 are isolated from each other. When the puncture-proof spacer 5 needs to be removed, it can be quickly pulled out from the spacer insertion slot 11, which is quite convenient for operation.

In some embodiments, as shown in Figures 7 to 10, in order to better avoid the formation of a gas plug in the cavity of the outer cylinder and affecting the smooth insertion and removal of the liquid sampling tube assembly 3, the tube plug 33 can be placed radially outward The rim forms a pipe plug exhaust passage 331 arranged along the extension direction of the outer barrel cavity, and the barrel cavity area of the outer barrel cavity between the pipe plug 33 and the puncture needle installation end can pass through the pipe plug exhaust passage 331 And the peripheral wall exhaust gap between the above-mentioned liquid sampling tube 31 and the inner peripheral wall of the outer cylinder communicates with the atmosphere. In other words, the barrel cavity of the outer cylinder is in the barrel cavity area between the pipe plug 33 and the puncture needle mounting end, the pipe plug exhaust passage 331 and the peripheral wall exhaust gap are in sequence connected, and the atmospheric environment is connected in sequence.

In order to improve the ventilation effect and make the structure of the pipe plug 33 more uniform and reasonable, a plurality of pipe plug exhaust passages 331 that extend along the axial direction of the outer cylinder cavity and are sequentially spaced along the circumferential direction of the pipe plug 33 are provided.

The specific shape of the pipe plug exhaust passage 331 may be determined according to actual needs. For example, referring to FIGS. 7 and 8, a pipe plug exhaust groove serving as the pipe plug exhaust passage 331 may be formed on the outer peripheral wall of the pipe plug 33 The exhaust groove of the pipe plug is provided with a groove opening facing the radially outer side. In other words, the plug exhaust passage 331 may be set as an exhaust passage with an open peripheral wall. Alternatively, referring to Figures 9 and 10, the peripheral wall of the pipe plug exhaust channel 331 can be set as a closed peripheral wall, that is, the pipe plug exhaust channel 331 can be set as a peripheral wall closed exhaust channel. In addition, the cross-section of the pipe plug exhaust passage 331 can be set to have different shapes such as a semicircle, a square or an arc.

In some embodiments, the pipe plug 33 includes a pipe plug center portion for sealing the nozzle of the liquid extraction pipe and an outer ring portion of the pipe plug located radially outside the pipe plug center portion and provided with a pipe plug exhaust channel 331, which is To ensure internal and external ventilation, the outer ring portion of the pipe plug can be at least partially set as a loose ventilation structure, but it is still necessary to ensure that the central portion of the pipe plug has a tightness.

In order to ensure that the inner end of the puncture needle does not shake when piercing the tube plug 33 and affect the accuracy of puncture, a puncture guide hole 332 for guiding the inner end of the puncture needle can be provided at the end of the tube plug 33. And the outer contour shape of the inner end of the puncture needle and the shape of the blind guide hole 332 are matched with each other. For example, referring to FIG. 3, the inner end of the puncture needle and the puncture blind guide hole 332 may be set in a long tapered shape that matches with each other.

It should be noted that in the process of piercing the tube plug 33 at the inner end of the puncture needle, it may happen that the axial water outlet 22 at the inner end of the puncture needle is blocked by the material of the tube plug, causing the drainage to be blocked and the device not working properly. jobs. Therefore, in order to avoid the occurrence of cut-off, the peripheral wall water outlet hole 21 communicating with the needle cavity of the puncture needle 2 can be provided on the outer peripheral wall of the inner end of the puncture needle. With this structure, even if the axial water outlet hole 22 is blocked by the pipe plug material, The aqueous humor can also flow out into the lumen of the liquid collection tube through the water outlet hole 21 of the peripheral wall, thereby ensuring the working reliability of the device.

In addition, the axial distance between the peripheral wall outlet hole 21 and the axial outlet hole 22 should not be too large, otherwise when the axial outlet hole 22 is inserted into the lumen of the liquid sampling tube, the peripheral wall outlet hole 21 is still located in the pipe plug 33 and is blocked. As a result, the water outlet hole 21 of the peripheral wall loses its effectiveness. For this reason, the axial distance between the hole center of the peripheral wall water outlet hole 21 and the hole center of the axial water outlet hole 22 can be preferably set to be no more than 3 mm to ensure that when the axial water outlet hole 22 is inserted into the lumen of the liquid collection tube, the peripheral wall The water outlet 21 can also be located in the lumen of the liquid sampling tube without being blocked.

In the description of the present invention, it should be understood that the terms "center", "longitudinal", "transverse", "length", "width", "thickness", "upper", "lower", "front", " "Back", "Left", "Right", "Vertical", "Horizontal", "Top", "Bottom", "Inner", "Outer", "Clockwise", "Counterclockwise", "Axial", The orientation or positional relationship indicated by "radial", "circumferential", etc. is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying the pointed device or element It must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation to the present invention.

In addition, the terms "first" and "second" are only used for descriptive purposes, and cannot be understood as indicating or implying relative importance or implicitly indicating the number of indicated technical features. Therefore, the features defined with "first" and "second" may explicitly or implicitly include at least one of the features. In the description of the present invention, "a plurality of" means at least two, such as two, three, etc., unless otherwise specifically defined.

In the present invention, unless otherwise clearly defined and defined, the terms "installed", "connected", "connected", "fixed" and other terms should be understood in a broad sense, for example, it can be a fixed connection or a detachable connection. , Or integrated; it can be mechanically connected, or it can be electrically connected or can communicate with each other; it can be directly connected or indirectly connected through an intermediate medium, it can be the internal communication of two components or the interaction relationship between two components, Unless otherwise clearly defined. For those of ordinary skill in the art, the specific meaning of the above-mentioned terms in the present invention can be understood according to specific circumstances.

In the present invention, unless expressly stipulated and defined otherwise, the first feature “on” or “under” the second feature may be in direct contact with the first and second features, or the first and second features may be indirectly through an intermediary. contact. Moreover, the "above", "above" and "above" of the first feature on the second feature may mean that the first feature is directly above or obliquely above the second feature, or simply means that the level of the first feature is higher than the second feature. The “below”, “below” and “below” of the second feature of the first feature may mean that the first feature is directly below or obliquely below the second feature, or it simply means that the level of the first feature is smaller than the second feature.

In the description of this specification, descriptions with reference to the terms "one embodiment", "some embodiments", "examples", "specific examples", or "some examples" etc. mean specific features described in conjunction with the embodiment or example , Structure, materials or features are included in at least one embodiment or example of the present invention. In this specification, the schematic representations of the above-mentioned terms do not necessarily refer to the same embodiment or example. Moreover, the described specific features, structures, materials or characteristics can be combined in any one or more embodiments or examples in a suitable manner. In addition, those skilled in the art can combine and combine the different embodiments or examples and the characteristics of the different embodiments or examples described in this specification without contradicting each other.

Although the embodiments of the present invention have been shown and described above, it can be understood that the above-mentioned embodiments are exemplary and should not be construed as limiting the present invention. Those of ordinary skill in the art can comment on the foregoing within the scope of the present invention. The embodiment undergoes changes, modifications, substitutions and modifications.

Claims

An aqueous humor collection device, characterized in that the aqueous humor collection device (100) comprises:

The outer cylinder (1) is provided with a puncture needle installation end and a liquid sampling tube installation end;

The puncture needle (2) is inserted into the puncture needle installation end and includes an outer end of the puncture needle and an inner end of the puncture needle that extends into the cavity of the outer cylinder;

The sampling tube assembly (3) is pluggable and movably inserted from the installation end of the sampling tube into the barrel cavity of the outer cylinder and includes a sampling tube (31) and a tube for sealing the outer cylinder. Tube plug (33) of the nozzle of the liquid sampling tube in the cavity;

Wherein, a ventilation structure is formed between the liquid sampling tube assembly (3) and the inner peripheral wall of the outer cylinder, and the ventilation structure communicates with the cavity of the outer cylinder between the inner end of the puncture needle and the tube plug (33). In the cylindrical cavity area between the liquid collection device (100), the aqueous humor collection device (100) further includes a position for limiting the displacement of the liquid collection tube assembly (3) in the radial direction and for connecting the liquid collection tube assembly (3) to the A contact damping limit buffer structure is formed between the inner peripheral walls of the outer cylinder.
The aqueous humor collection device according to claim 1, wherein the limiting buffer structure comprises a limiting protrusion protruding from the outer peripheral wall of the sampling tube assembly (3) or from the inner peripheral wall of the outer cylinder From (6), the radial ends of the limiting protrusion (6) are respectively connected with the outer peripheral wall of the liquid sampling tube assembly (3) and the inner peripheral wall of the outer cylinder.
The aqueous humor collection device according to claim 2, characterized in that the limit buffer structure comprises a spaced-apart or continuous extension along the length of the tube assembly (3). The limiting protrusion (6), the total span of the limiting protrusion (6) along the tube length direction is not less than half of the tube length of the liquid sampling tube.
The aqueous humor collection device according to claim 2, wherein the limiting protrusion (6) is integrally formed on the outer peripheral wall of the liquid collection tube (31); or, the liquid collection tube assembly ( 3) comprising a tube set (34) sheathed on the outer peripheral wall of the liquid collection tube (31), and the limiting protrusion (6) is arranged on the outer peripheral wall of the tube set (34).
The aqueous humor collection device according to claim 4, wherein the tube set (34) is an elastic tube set.
The aqueous humor collection device according to claim 2, wherein the limit buffer structure comprises a plurality of the limit protrusions (6) arranged at intervals in the circumferential direction, and a plurality of the limit protrusions The gap between (6) is formed as the ventilation structure;

Alternatively, the limiting buffer structure includes the limiting protrusion (6) continuously extending in the circumferential direction, and between the limiting protrusion (6) and the outer peripheral wall of the sampling tube assembly (3) or An exhaust gap serving as the ventilation structure is formed between the limiting protrusion (6) and the inner peripheral wall of the outer cylinder.
The aqueous humor collection device according to claim 6, wherein the plurality of limiting protrusions (6) arranged at intervals along the circumferential direction are all convex points.
The aqueous humor collection device according to claim 6, characterized in that the limiting protrusion (6) continuously extending in the circumferential direction is shaped like a corrugated or helical tooth.
The aqueous humor collection device according to claim 1, wherein the liquid sampling tube assembly (3) further comprises a supporting tube frame (32) for fixedly installing the liquid sampling tube (31), and the supporting tube The limiting buffer structure is formed between the outer peripheral wall of the frame (32) and the inner peripheral wall of the outer cylinder.
The aqueous humor collection device according to claim 9, characterized in that the liquid collection tube (31) and the supporting tube frame (32) are fixed by screw connection or snap connection.