WO2020242256A3 - 인간 미뢰 오가노이드의 배양용 조성물 - Google Patents

인간 미뢰 오가노이드의 배양용 조성물 Download PDF

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WO2020242256A3
WO2020242256A3 PCT/KR2020/007028 KR2020007028W WO2020242256A3 WO 2020242256 A3 WO2020242256 A3 WO 2020242256A3 KR 2020007028 W KR2020007028 W KR 2020007028W WO 2020242256 A3 WO2020242256 A3 WO 2020242256A3
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human taste
taste bud
bud organoid
present
organoid
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WO2020242256A2 (ko
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김철훈
권순성
조형주
문석준
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연세대학교 산학협력단
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Priority claimed from KR1020200064908A external-priority patent/KR102334245B1/ko
Publication of WO2020242256A2 publication Critical patent/WO2020242256A2/ko
Publication of WO2020242256A3 publication Critical patent/WO2020242256A3/ko

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Abstract

본 발명은 인간 미뢰(taste bud) 오가노이드 배양용 배지 조성물 및 이를 이용한 인간 미뢰 오가노이드의 제조 방법에 관한 것이다. 본 발명은 다각적인 실험을 통해 섬세한 감각기관인 인간 미뢰 특이적 필수 배양성분을 선별함으로써, 아직까지 제안된 적 없는 인간 미뢰 오가노이드를 위한 최적의 배양 환경을 제공한다. 이에, 본 발명은 인간 미뢰의 유전자 발현 프로파일과 미각원에 대한 반응 등 생체 내 주요 기능 및 표현형이 완전히 재연되는 효율적인 오가노이드 제작에 유용하게 이용될 수 있다.
PCT/KR2020/007028 2019-05-29 2020-05-29 인간 미뢰 오가노이드의 배양용 조성물 WO2020242256A2 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
KR10-2019-0062988 2019-05-29
KR20190062988 2019-05-29
KR1020200064908A KR102334245B1 (ko) 2019-05-29 2020-05-29 인간 미뢰 오가노이드의 배양용 조성물
KR10-2020-0064908 2020-05-29

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WO2020242256A2 WO2020242256A2 (ko) 2020-12-03
WO2020242256A3 true WO2020242256A3 (ko) 2021-07-08

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CN114561335B (zh) * 2022-02-11 2024-06-25 中山大学 一种外周血单个核细胞制备肝脏类器官的方法
CN116396939A (zh) * 2023-05-11 2023-07-07 杭州济扶科技有限公司 一种适应泛癌种类器官高效扩增的组合式培养基及应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20140037210A (ko) * 2011-06-10 2014-03-26 코닌클리즈케 네덜란드세 아카데미 반 베텐샤펜 줄기세포용 배양 배지
US20170191030A1 (en) * 2014-05-16 2017-07-06 Koninklijke Nederlandse Akademie Van Wetenschappen Improved culture method for organoids
US20170275592A1 (en) * 2014-11-27 2017-09-28 Koninklijke Nederlandse Akademie Van Wetenschappen Culture medium
WO2017199811A1 (ja) * 2016-05-18 2017-11-23 学校法人慶應義塾 オルガノイド培養用細胞培養培地、培養方法、及びオルガノイド

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20140037210A (ko) * 2011-06-10 2014-03-26 코닌클리즈케 네덜란드세 아카데미 반 베텐샤펜 줄기세포용 배양 배지
US20170191030A1 (en) * 2014-05-16 2017-07-06 Koninklijke Nederlandse Akademie Van Wetenschappen Improved culture method for organoids
US20170275592A1 (en) * 2014-11-27 2017-09-28 Koninklijke Nederlandse Akademie Van Wetenschappen Culture medium
WO2017199811A1 (ja) * 2016-05-18 2017-11-23 学校法人慶應義塾 オルガノイド培養用細胞培養培地、培養方法、及びオルガノイド

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