WO2020224330A1 - 微流控装置、用于微流控装置的操作方法及控制装置 - Google Patents
微流控装置、用于微流控装置的操作方法及控制装置 Download PDFInfo
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- WO2020224330A1 WO2020224330A1 PCT/CN2020/079596 CN2020079596W WO2020224330A1 WO 2020224330 A1 WO2020224330 A1 WO 2020224330A1 CN 2020079596 W CN2020079596 W CN 2020079596W WO 2020224330 A1 WO2020224330 A1 WO 2020224330A1
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- target droplet
- microfluidic chip
- touch panel
- microfluidic
- touch
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- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F3/00—Input arrangements for transferring data to be processed into a form capable of being handled by the computer; Output arrangements for transferring data from processing unit to output unit, e.g. interface arrangements
- G06F3/01—Input arrangements or combined input and output arrangements for interaction between user and computer
- G06F3/03—Arrangements for converting the position or the displacement of a member into a coded form
- G06F3/041—Digitisers, e.g. for touch screens or touch pads, characterised by the transducing means
- G06F3/0412—Digitisers structurally integrated in a display
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- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F3/00—Input arrangements for transferring data to be processed into a form capable of being handled by the computer; Output arrangements for transferring data from processing unit to output unit, e.g. interface arrangements
- G06F3/01—Input arrangements or combined input and output arrangements for interaction between user and computer
- G06F3/048—Interaction techniques based on graphical user interfaces [GUI]
- G06F3/0487—Interaction techniques based on graphical user interfaces [GUI] using specific features provided by the input device, e.g. functions controlled by the rotation of a mouse with dual sensing arrangements, or of the nature of the input device, e.g. tap gestures based on pressure sensed by a digitiser
- G06F3/0488—Interaction techniques based on graphical user interfaces [GUI] using specific features provided by the input device, e.g. functions controlled by the rotation of a mouse with dual sensing arrangements, or of the nature of the input device, e.g. tap gestures based on pressure sensed by a digitiser using a touch-screen or digitiser, e.g. input of commands through traced gestures
Definitions
- the embodiments of the present disclosure relate to a microfluidic device, an operation method and a control device for the microfluidic device.
- the microfluidic chip has a path for the droplet movement designed in advance, so after the design is completed, the microfluidic drive circuit can only drive processing for the existing path.
- the microfluidic drive circuit can only drive processing for the existing path.
- several buttons with specific functions are designed in advance. When the microfluidic chip is used, only one of these functions can be selected, so that relatively limited functions can be realized.
- At least one embodiment of the present disclosure provides a microfluidic device, which includes:
- a touch panel wherein the touch panel is configured to detect contact actions on a touch surface of the touch panel
- the microfluidic chip is configured to perform a preset operation on the target droplet according to the detected contact action.
- the microfluidic device further includes a display panel, wherein the display panel is configured to display the target droplet,
- the touch panel is located on the display side of the display panel, and
- the microfluidic chip is configured to perform the preset operation on the target droplet according to the operation of the contact action on the target droplet displayed on the display panel.
- the microfluidic device further includes an image capture device, wherein the image capture device is configured to capture image information of the target droplet and transmit the image information of the target droplet To the display panel, and
- the display panel is configured to display the target droplet based on image information of the target droplet.
- the microfluidic device further includes a controller, wherein the controller is signally connected to the touch panel and the microfluidic chip, and is configured to respond to the touch panel detecting The reached contact action controls the microfluidic chip to perform the preset operation on the target droplet.
- the controller is further configured to plan the movement route of the target droplet according to the contact action, and control the microfluidic chip to drive The target droplet moves according to the movement route.
- any two of the touch panel, the microfluidic chip, and the controller can be detachably connected.
- the detection area of the touch panel corresponds to the operation area of the microfluidic chip.
- the touch panel and the microfluidic chip overlap in a direction perpendicular to the touch surface of the touch panel, and the touch panel
- the detection area is at least partially transparent, so that the operating area of the microfluidic chip is visible.
- At least one embodiment of the present disclosure further provides a control device, which includes: a controller, a first interface, and a second interface, wherein the first interface is configured to be signal-connected to the touch panel, and the second interface is configured to Signal connection with microfluidic chip,
- the controller is configured to obtain the detection result of the touch action by the touch panel, and control the microfluidic chip to perform a preset operation on the target droplet according to the detection result.
- the controller includes:
- a system-on-chip configured to connect to the first interface signal and determine touch information according to the touch signal from the touch panel received by the first interface
- the micro control unit is configured to be connected to the second interface signal, generate a driving signal according to the touch information provided by the system on chip, and output to the microfluidic chip through the second interface.
- At least one embodiment of the present disclosure also provides an operating method for a microfluidic device, the microfluidic device including a touch panel and a microfluidic chip, and the method includes:
- the microfluidic chip performs a preset operation on the target droplet according to the detected contact action.
- the microfluidic device further includes a display panel configured to display the target droplet
- the method further includes: displaying the target droplet through the display panel.
- the step of performing a preset operation on the target droplet by the microfluidic chip according to the detected contact action includes:
- the preset operation is performed on the target droplet.
- the microfluidic device further includes an image acquisition device, and
- the displaying the target droplet on the display panel includes:
- the microfluidic device further includes a controller, and the controller is in signal connection with the touch panel and the microfluidic chip, and
- the performing the preset operation on the target droplet according to the detected contact action by the microfluidic chip includes: in response to the contact action detected by the touch panel, controlling by the controller The microfluidic chip performs the preset operation on the target droplet according to the detected contact action.
- the preset operation includes at least one of the following: moving, separating, polymerizing, applying voltage, and heating.
- the contact action includes a click action
- the target droplet is a droplet located at a corresponding position on the microfluidic chip where the click action occurs.
- the contact action includes: a sliding action starting from a first position on the touch panel and continuing to a second position on the touch panel, as well as
- the target droplet is a droplet located on a corresponding track on the microfluidic chip on the track of the sliding motion.
- the step of performing a preset operation on the target droplet by the microfluidic chip according to the detected contact action includes:
- the movement route of the target droplet is planned according to the trajectory of the sliding motion detected by the touch panel, and the microfluidic chip is controlled to drive the target droplet to move according to the movement route.
- Fig. 1 is a schematic structural block diagram of a microfluidic device according to at least one embodiment of the present disclosure.
- Fig. 2 is a schematic structural diagram of a touch panel according to at least one embodiment of the present disclosure.
- Fig. 3 is a top view of a microfluidic chip according to at least one embodiment of the present disclosure.
- Fig. 4 is a cross-sectional view taken along the line L-L' in Fig. 3.
- Fig. 5 is a schematic structural diagram of a control device according to at least one embodiment of the present disclosure.
- FIG. 6 is a schematic diagram of an example of a trajectory of a contact action on a touch panel according to at least one embodiment of the present disclosure.
- Fig. 7 is another structural diagram of a control device according to at least one embodiment of the present disclosure.
- Fig. 8 is a schematic structural block diagram of a microfluidic device according to at least one embodiment of the present disclosure.
- Fig. 9 is a schematic structural block diagram of a microfluidic device according to at least one embodiment of the present disclosure.
- FIG. 10 is a schematic flowchart of an operating method for a microfluidic device according to at least one embodiment of the present disclosure.
- the microfluidic chip has a path for the droplet movement designed in advance, so after the design is completed, the microfluidic drive circuit can only drive processing for the existing path.
- At least one embodiment of the present disclosure provides a microfluidic device, an operation method for the microfluidic device, and a control device, which can control the microfluidic chip through a touch panel to operate the liquid to be detected , So the operation mode is more flexible and the function is richer.
- Fig. 1 is a schematic structural block diagram of a microfluidic device according to at least one embodiment of the present disclosure.
- the microfluidic device 100 according to at least one embodiment of the present disclosure includes a touch panel 110, a microfluidic chip 120 and a control device 130.
- the touch panel 110 is used to detect contact actions on the touch surface of the touch panel 110, and these contact actions may include a tap, a double tap, a long touch, a slide, and the like.
- the touch panel 110 may generate a detection signal according to a contact action on the touch surface of the touch panel 110.
- the detection signal may include a signal representing position information of the contact action on the touch panel 110, a signal representing pressing strength information of the contact action on the touch panel 110, a signal representing duration information of the contact action on the touch panel 110, and the like.
- the aforementioned position information may include, for example, coordinate information of a contact action on the touch panel 110.
- the touch panel 110 may include, but is not limited to, a resistive touch panel, an infrared touch panel, a surface acoustic wave touch panel, and a capacitive touch panel, for example, which is not limited in the embodiments of the present disclosure.
- the detection area of the touch panel 110 corresponds to the operation area of the microfluidic chip 120.
- the detection area of the touch panel 110 is The projection on the chip 120 is greater than or equal to the operating area of the microfluidic chip 120, so that the user's operations on the microfluidic chip 120 seen through the touch panel 110 can be detected;
- the microfluidic device 100 also includes a display panel for displaying an image of the microfluidic chip 120 and when the display panel overlaps the touch panel 110, the projection of the detection area of the touch panel 110 on the display panel is greater than or equal to that displayed on the display panel The operating area of the microfluidic chip 120 on the upper side, so that the user's operations on the microfluidic chip 120 seen through the touch panel 110 can be detected.
- the touch panel 110 can overlap the microfluidic chip 120 up and down, and the touch panel 110 is on the side facing the user, so that the user can perform touch operations.
- the touch panel The detection area of 110 can cover the operating area of the microfluidic chip 120 so as to overlap with the operating area of the microfluidic chip 120.
- the detection area of the touch panel 110 may be at least partially transparent, so that the operating area of the microfluidic chip 120 located on the back side of the touch panel 110 is visible, so that the user can intuitively observe and control the movement of the target droplet.
- the detection area of the touch panel 110 may have different degrees of transmittance, such as 100%, 90%, 80%, 70%, 60%, 50%, 40%, 30%, 20%, 10%, or 5%
- the transmittance is not limited in the embodiments of the present disclosure.
- Fig. 2 is a schematic structural diagram of a touch panel according to at least one embodiment of the present disclosure.
- the touch panel 110 is a capacitive touch panel, which is a mutual capacitance type, and includes a substrate 111, a plurality of first electrode bars 112, a plurality of second electrode bars 113, and a second signal line 114 and the first signal line 115.
- the substrate 111 includes a detection area 1111 and a lead area 1112 located around the detection area 1111; a plurality of first electrode strips 112 are arranged in parallel on the substrate 111 of the detection area 1111, and each first electrode strip 112 includes a plurality of spaced apart The first sub-electrode; a plurality of second electrode strips 113 are arranged in parallel on the substrate 111 of the detection area 1111, each second electrode strip 113 includes a plurality of second sub-electrodes arranged at intervals, and the second electrode strip 113 is located The extension line of ⁇ and the extension line where the first electrode strip 112 is located cross each other; the first signal line 115 is correspondingly connected to the first electrode strip 112, and the second signal line 114 is correspondingly connected to the second electrode strip 113.
- the first electrode bar 112 and the second electrode bar 113 are located in the detection area, and the second signal line 114 and the first signal line 115 are located in the lead area 1112.
- one of the first sub-electrode and the second sub-electrode may be a driving electrode, and the other may be a sensing electrode.
- the first sub-electrode and the second sub-electrode intersecting with it can form an induction capacitor at the intersection position, whereby a plurality of first sub-electrodes and a plurality of second sub-electrodes cross each other to obtain an array of inductive capacitors in the detection area , Used to detect touch operation.
- a foreign object such as a finger, etc.
- the second signal line 114 and the first signal line 115 detect the position of the corresponding inductive capacitor whose capacitance changes, and the contact can be located.
- the first signal line 115 and the second signal line 114 may be converged to the port area B so as to be electrically connected to an external control unit such as a control device through, for example, a flexible circuit board.
- the substrate 111 may be a separate transparent substrate, such as a glass substrate, a plastic substrate, etc., or it may reuse, for example, the surface layer of the microfluidic chip 120, such as a protective cover plate of the microfluidic chip 120 (for example, a glass substrate, Plastic substrate, etc.) or encapsulation layer, etc.
- the first electrode strip 112 and the second electrode strip 113 can be prepared by, for example, a transparent conductive material (such as ITO); the first electrode strip 112 and the second electrode strip 113 can be located in different layers on the substrate 111 and are composed of at least one insulating layer.
- the first electrode strip 112 and the second electrode strip 113 can be located in the same layer on the substrate 111, but cross each other at a position where they cross each other by bridging. insulation.
- the second signal line 114 and the first signal line 115 may be made of aluminum or aluminum alloy, copper or copper alloy, for example.
- touch panel 110 shown in FIG. 2 is only exemplary, and the comparison of the embodiments of the present disclosure is not limited.
- the microfluidic chip 120 is configured to perform a preset operation on the target droplet according to the detected contact action, where the target droplet is on the microfluidic chip 120 or in the microfluidic chip 120.
- the preset operation may include, but is not limited to, moving the target droplet, separating the target droplet, polymerizing the target droplet, applying voltage to the target droplet, heating the target droplet, etc., which are not limited in the embodiments of the present disclosure.
- FIG. 3 is a top view of a microfluidic chip according to at least one embodiment of the present disclosure
- FIG. 4 is a cross-sectional view taken along the line L-L' in FIG. 3.
- the microfluidic chip 120 includes an operating area 1221 shown by a dashed frame.
- the operating area 1221 includes a drive array.
- the drive array includes a plurality of drive units 1222 distributed in an array. Each drive unit 1222 is configured to be powered on. Operate the droplet under the control of the signal.
- the driving unit 1222 is located on the base substrate 401.
- the driving unit 1222 may be directly formed on the base substrate 401, or may be prepared as an independent device and then bonded to the base substrate 401 by means of bonding.
- the base substrate 401 may also be a glass substrate, a plastic substrate, or the like.
- the microfluidic chip 120 may adopt a passive driving method or an active driving method, which is not limited in the embodiment of the present disclosure.
- the following article will take the active driving mode as an example for description.
- each driving unit 1222 may include a switching element and a driving electrode 409 electrically connected to the switching element.
- the driving electrode 409 operates the liquid droplet when a voltage is applied.
- Each switching element is used to provide a driving signal to one or more driving electrodes 409.
- the switching elements and the driving electrodes 409 correspond one-to-one.
- the switching element is shown in the form of a thin film transistor, but those skilled in the art will understand that the switching element can also be implemented in other forms, such as a field effect transistor, which is not limited in the embodiments of the present disclosure.
- the driving electrode 409 can be formed of, for example, any suitable material such as metal (such as alloy), doped semiconductor material (such as polysilicon), oxide conductive material (such as indium tin oxide (ITO), indium tin oxide (IZO)), etc.
- metal such as alloy
- doped semiconductor material such as polysilicon
- oxide conductive material such as indium tin oxide (ITO), indium tin oxide (IZO)
- ITO indium tin oxide
- IZO indium tin oxide
- a switching element taking a thin film transistor may include a gate 402, a gate insulating layer 403, an active layer 404, a first electrode 405, and a second electrode 406.
- the first electrode 405 is a source electrode and the second electrode 406 is a drain electrode.
- the first electrode 405 may also be a drain electrode, and the second electrode 406 is also a drain electrode. It may be a source electrode, which is not limited in the embodiments of the present disclosure.
- An insulating layer or a dielectric layer 407 is formed between the driving electrode 409 and the thin film transistor. The driving electrode 409 is in electrical contact with the second electrode 406 through the through hole 408 in the insulating layer 407 to receive the electrical signal from the second electrode 406.
- the microfluidic chip 120 may further include a hydrophobic layer 411 formed on the surface of the microfluidic chip 120 for carrying liquid droplets.
- the hydrophobic layer 411 can prevent the droplets from penetrating into the microfluidic chip 120, reduce the loss of the droplets, and help the droplets move on the microfluidic chip 120.
- the hydrophobic layer 411 is located on the surface of the driving electrode 409 away from the base substrate 401.
- the hydrophobic layer 411 can increase the surface tension gradient, thereby facilitating the movement of liquid droplets on the microfluidic chip 120.
- the hydrophobic layer 411 may be directly formed on the surface of the driving electrode 409, or an insulating layer 410 may be formed between the hydrophobic layer 411 and the driving electrode 409, thereby electrically insulating the driving electrode 409 from the droplet.
- the insulating layer 410 can also function as a flat layer, so that the microfluidic chip 120 has a flat surface.
- the hydrophobic layer 411 may be passed through Teflon, (perfluoro (1-butenylvinylether) polymer) and other materials, the insulating layer 410 may be formed of an inorganic insulating material or an organic insulating material, such as a resin, but the embodiment of the present disclosure does not limit this.
- the microfluidic chip 120 may also include a controller, a gate driving circuit, and a data driving circuit.
- the controller is coupled to the gate drive circuit and the data drive circuit, receives input signals and provides timing signals, drive signals, etc. to the gate drive circuit and the data drive circuit according to the input signals to control the gate drive circuit and the data drive circuit to work synchronously .
- the gate driving circuit may apply scan signals to the driving array, for example row by row, through the gate lines to control the on or off of the switching elements, and the data driving circuit may apply driving signals to the driving array through the data lines.
- the gate of the switching element of each driving unit 1222 is electrically connected to the gate line corresponding to the row where the driving unit is located, and the first pole 405 of the switching element is electrically connected to the data line of the column where the driving unit is located, thereby electrically connecting to the data driving circuit
- the driving signal can be provided to the driving electrode 409 when the switching element is turned on.
- the microfluidic chip 120 may further include a port part that is connected to an external signal through, for example, a flexible circuit board to receive an input signal (control signal) and provide the input signal to the controller of the microfluidic chip 120 to Generate corresponding signals for the gate drive circuit and the data drive circuit.
- microfluidic chip 120 shown in FIG. 3 and FIG. 4 is only exemplary, and the comparison of the embodiments of the present disclosure is not limited.
- the microfluidic device 100 may further include a control device 130.
- the control device 130 is signally connected to the touch panel 110 and the microfluidic chip 120 to generate a control signal for controlling the microfluidic chip 120 according to the detection signal provided by the touch panel 110 to perform a preset operation on the target droplet.
- the control device 130 may include: a first interface 1311, a controller 1312, and a second interface 1313.
- the first interface 1311 is configured for signal connection with the touch panel 110
- the second interface 1313 is configured for signal connection with the microfluidic chip 120
- the controller 1312 is configured to obtain the detection of the touch panel 110 on the touch surface of the touch panel 110
- the microfluidic chip 120 is controlled to perform a preset operation on the target droplet according to the detection result.
- the first interface 1311 may be electrically connected to the port area B of the touch panel 110 shown in FIG.
- the second interface 1313 may be through, for example, the port of the flexible circuit board and the microfluidic chip 120
- the areas are electrically connected to send input signals required by the microfluidic chip 120, so that a driving signal can be provided to the first pole 405 of the switching element of the corresponding driving unit in the driving array of the microfluidic chip 120, that is, the The driving electrode 409 of the driving unit provides a driving signal to perform a driving operation corresponding to the touch signal on the liquid drop.
- the first interface 1311 may be configured to be directly or indirectly coupled to the touch panel 110 through a network (such as the Internet, wireless LAN, etc.) to receive touch signals.
- the second interface 1313 may be configured to be directly or indirectly coupled to the microfluidic chip 120 through a network (such as the Internet, wireless LAN, etc.) to provide a driving signal to the microfluidic chip 120.
- the first interface 1311 and the second interface 1313 may be I 2 C (Inter-Integrated Circuit, inter-integrated circuit) interfaces, SPI (Serial Peripheral Interface, serial peripheral interface) interfaces, or universal serial interfaces.
- I 2 C Inter-Integrated Circuit, inter-integrated circuit
- SPI Serial Peripheral Interface, serial peripheral interface
- any two of the control device 130, the touch panel 110 and the microfluidic chip 120 can be detachably connected to facilitate maintenance and replacement of the microfluidic device.
- any two of the control device 130, the touch panel 110 and the microfluidic chip 120 may also be fixedly connected, which is not limited in the embodiment of the present disclosure.
- the touch panel 110 and the microfluidic chip 120 may be connected by a detachable fastening device, such as a snap-fit fastening device or a magnetic fastening device.
- the touch panel 110 and the microfluidic chip 120 may be fixedly connected by an adhesive or the like.
- the detachable connection between the control device 130 and the touch panel 110 and/or the microfluidic chip 120 can be realized by, for example, a plug and a socket.
- the controller 1312 may include, for example, a field programmable gate array (FPGA), a program-specific integrated circuit (ASIC), a program-specific standard product (ASSP), a system on chip (SOC), a complex programmable logic device (CPLD), and digital signal The processor (DSP), etc., the embodiment of the present disclosure does not limit this.
- the controller 1312 may be connected to the first interface 1311 and the second interface 1313 by signals, for example, via a bus.
- the controller 1312 can also be configured to plan the movement route of the target droplets in the microfluidic chip 120 or on the microfluidic chip 120 according to the contact action on the touch surface of the touch panel 110, and control the microfluidic chip 120 to drive The target droplet moves according to the movement route.
- the controller 1312 may be configured to: in the case that the contact action is a click action, determine the droplet located at the corresponding position on the microfluidic chip 120 where the click action occurs as the target droplet and to select the selected target The droplet performs a preset operation.
- the controller 1312 may be configured to: in the case where the contact action is a sliding action starting from the first position on the touch panel 110 and continuing to the second position on the touch panel 110, the first position is located in the micro
- the droplet at the corresponding position on the fluidic chip 120 is determined as the target droplet, the trajectory of the sliding motion is identified, and the movement route of the target droplet is planned according to the trajectory, and the microfluidic chip 120 is controlled to drive the target droplet according to the planned Movement route moves.
- the controller 1312 may be configured to plan the movement route of the target droplet as the trajectory of the sliding motion, so that the target droplet moves along the trajectory of the sliding motion.
- the controller 1312 can also be configured to control the microfluidic chip 120 so that the target droplet moves at the speed of the sliding motion.
- FIG. 6 is a schematic diagram of an example of the trajectory of a contact action on a touch panel according to at least one embodiment of the present disclosure.
- an exemplary liquid in the microfluidic chip 120 or on the microfluidic chip 120 is also shown.
- D1-D4 and the driving unit 1222 of the microfluidic chip 120.
- the sliding motion starts from the first position P1 on the touch panel 110 and continues to the second position P2 on the touch panel 110.
- the controller 1312 can be configured to place the first position P1 in the microfluidic chip
- the droplet D1 at the corresponding position on the 120 is determined as the target droplet, the trajectory T of the sliding motion is recognized, and the microfluidic chip 120 is controlled to drive the droplet S1 to move according to the trajectory T.
- the controller 1312 may be configured to: in the case where the contact action is a sliding action starting from a first position on the touch panel 110 and continuing to a second position on the touch panel 110, set the trajectory of the sliding action to The droplet on the corresponding trajectory on the microfluidic chip is determined to be the target droplet, the trajectory of the sliding motion is identified and the movement route of the target droplet is planned according to the trajectory, and the microfluidic chip 120 is controlled to drive the target droplet to follow The planned movement route moves.
- the controller 1312 may be configured to plan the movement route of the target droplet as the trajectory of the sliding motion, so that the target droplet moves along the trajectory of the sliding motion.
- the controller 1312 may also be configured to control the microfluidic chip 120 so that the target droplet moves at the speed of the sliding motion. As shown in FIG. 6, the sliding motion starts from the first position P1 on the touch panel 110 and continues to the second position P2 on the touch panel 110.
- the controller 1312 can be configured to set the trajectory T of the sliding motion in the microfluidic control
- the droplets D1 to D4 on the corresponding track on the chip 120 are determined as target droplets, and the microfluidic chip 120 is controlled to drive the droplets D1 to D4 to move according to the track T.
- the droplets in the operation area of the microfluidic chip 120 may also include droplets of various reagents (such as diluents, stains, etc.), so as to The droplets of the liquid to be tested are mixed with the reagents to facilitate subsequent analysis and detection.
- various reagents such as diluents, stains, etc.
- the controller 1312 may include a system on chip (SoC) 13121 signally connected to the first interface 1311 and a micro control unit (MCU) signally connected to the second interface 1313 131122.
- SoC system on chip
- MCU micro control unit
- the system-on-chip 13121 is configured to process the touch signals received by the first interface 1311 to determine touch information, where the touch information includes but is not limited to the position information of the contact action on the touch panel 110, and the contact action on the touch panel 110. Information on the intensity of the pressing on the 110, the duration of the contact action on the touch panel 110, and so on.
- the micro control unit 13122 is configured to generate and output a driving signal for the microfluidic chip according to the touch information provided by the system on chip 13121.
- control device 130 may be provided on a flexible circuit board (FPC), for example, to reduce the size of the microfluidic device 100.
- FPC flexible circuit board
- Fig. 8 is a schematic structural block diagram of a microfluidic device according to at least one embodiment of the present disclosure.
- the microfluidic device 200 may further include a display panel 140.
- the display panel 140 is used to display target droplets on or in the microfluidic chip 120, and the display panel 140 is arranged such that the touch panel 110 is located on the display side of the display panel 140.
- the display panel 140 may include, for example, a liquid crystal display panel, an organic light emitting diode display panel, an electronic paper display panel, etc., which are not limited in the embodiments of the present disclosure.
- the display area of the display panel 140 can display liquid droplets in the operation area of the microfluidic chip 120, and the detection area of the touch panel 110 can overlap the display area of the display panel 140, and correspond to the operation area of the microfluidic chip 120.
- the shapes of the two are in a similar relationship, so geometrically, the points in the detection area of the touch panel 110 and the points in the operation area of the microfluidic chip 120 have a one-to-one correspondence.
- the microfluidic chip 120 is used to operate the target droplet displayed on the display panel 140 according to the contact action on the touch surface of the touch panel 110, and perform the aforementioned preset operation on the target droplet .
- the display panel 140 can magnify and display the droplets in the operation area of the microfluidic chip 120, so that the droplets can be operated more accurately.
- the microfluidic chip 120 is in an environment that is not suitable for human entry such as high temperature or dust-free, the touch panel 110 and the display panel 140 can be arranged separately from the microfluidic chip 120, so that the microfluidic The droplets in the control chip 120 or on the microfluidic chip 120 are operated remotely.
- the display panel 140 may be signally connected to the control device 130 (for example, the wired connection shown in FIG. 8), so that display can be performed under the control of the control device 130, for example, the display panel 140 may be
- the control device 130 receives signals such as an opening signal, a closing signal, and a data signal of the image of the microfluidic chip 120 to be displayed.
- the display panel 140 may not be connected to the control device 130, but may be signal-connected to other control devices provided separately to receive, for example, a turn-on signal, a turn-off signal, a data signal of the image of the microfluidic chip 120 to be displayed, etc. Signal, the embodiment of the present disclosure does not limit this.
- Fig. 9 is a schematic structural block diagram of a microfluidic device according to at least one embodiment of the present disclosure.
- the microfluidic device 300 may further include an image acquisition device 150.
- the image acquisition device 150 is used to collect the image information of the target droplet on the microfluidic chip 120 or in the microfluidic chip 120, and provide the image information of the target droplet to the control device 130, and the control device 130 is checking the image information After necessary processing, it is transmitted to the display panel 140, and the display panel 140 is used to display the target droplet based on the image information of the target droplet.
- the image acquisition device 150 may be configured to capture an image of the operating area of the microfluidic chip 120 to obtain droplet image information in the operating area of the microfluidic chip 120.
- the image capture device 150 may include, for example, a camera, etc., which is not limited in the embodiment of the present disclosure.
- the image capture device 150 may be signally connected to the control device 130 (for example, the wired connection shown in FIG. 9), so that the microfluidic chip 120 can be captured under the control of the control device 130.
- the image capture device 150 may receive an on signal from the control device 130, a control signal for instructing the image capture device 150 to capture an image, and other signals, and the image capture device 150 may send an image of the target droplet on the microfluidic chip 120.
- the control device 130 transmits the data signal of the collected image so that the control device 130 can process the data signal (for example, identify, filter, denoise, etc.) and transmit the processed data signal to the display panel 140.
- the image capture device 150 may not be connected to the control device 130, but may be signal-connected to other control devices provided separately to receive signals such as a turn-on signal, a control signal instructing the image capture device 150 to capture images, etc.
- the embodiment does not limit this.
- the image capture device 150 may also be directly signal connected with the display panel 140 to directly transmit the data signal of the captured image to the display panel 140, which is not limited in the embodiments of the present disclosure.
- the microfluidic device can realize the control of the microfluidic chip through the touch panel to operate the liquid to be detected, which improves the interactivity and operability.
- At least one embodiment of the present disclosure also provides an operating method for a microfluidic device, which can be implemented in the microfluidic device according to any of the above-mentioned embodiments.
- an operating method 1000 for a microfluidic device according to at least one embodiment of the present disclosure may include:
- S1400 Perform a preset operation on the target droplet through the microfluidic chip according to the detected contact action.
- the microfluidic device may further include a display panel, wherein the display panel is used to display target droplets, wherein the target droplets are on or in the microfluidic chip.
- the method may further include: displaying the target droplet on the display panel, and the above-mentioned step S940 may include: contacting the target displayed on the display panel by the microfluidic chip according to the contact action.
- Droplet operations perform preset operations on target droplets.
- the microfluidic device may further include an image capture device, wherein the image capture device is used to capture image information of the target droplet on or in the microfluidic chip, and provide the target fluid The image information of the drop is transmitted to the display panel so that the display panel displays the target drop based on the image information of the target drop.
- the above step of displaying the target droplet through the display panel may include: acquiring image information of the target droplet through the image acquisition device, and transmitting the image information of the target droplet to the display panel And displaying the target droplet based on the image information of the target droplet through the display panel.
- the microfluidic device may further include a control device, wherein the control device is signally connected to the touch panel and the microfluidic chip.
- the control device can receive the detection result of the touch action on the touch surface of the touch panel by the touch panel, and based on the detection result, generate the input signal required for controlling the microfluidic chip, thereby enabling the drive array of the microfluidic chip
- the first pole of the switch element of the corresponding drive unit in the drive unit provides a drive signal, that is, a drive signal can be provided to the drive electrode of the drive unit, so as to drive the liquid droplet corresponding to the touch signal.
- the above-mentioned step S1400 may include: in response to the contact action detected by the touch panel, controlling the microfluidic chip by the controller to perform pre-processing on the target droplet according to the detected contact action. Set up operation.
- the above-mentioned contact action on the touch surface of the touch panel may include a click action
- the method may include: setting the position of the click action to the corresponding position on the microfluidic chip. Determined as the target drop.
- the above-mentioned contact action on the touch surface of the touch panel may include: a sliding action starting from the first position on the touch panel and continuing to the second position on the touch panel, and the method It may include: determining the droplet located on the trajectory of the sliding motion on the corresponding trajectory on the microfluidic chip as the target droplet.
- the foregoing preset operations may include, but are not limited to: moving the target droplet, separating the target droplet, polymerizing the target droplet, applying a voltage to the target droplet, heating the target droplet, etc.
- the embodiments of the present disclosure are to this No restrictions.
- the above step S1400 may include: planning the movement route of the target droplet according to the trajectory of the sliding motion detected by the touch panel, and controlling the microfluidic chip to drive the target droplet to move according to the movement. The route moves.
- the movement route of the target droplet can be planned according to the user's contact action, so that the target droplet moves according to the user's contact action.
- this step please refer to the description of the above embodiment of the microfluidic device, which will not be repeated here.
- the operating method for a microfluidic device can realize the control of the microfluidic chip through the touch panel to operate the liquid to be detected, which improves the interactivity and operability.
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Abstract
Description
Claims (19)
- 一种微流控装置,包括:触摸面板,其中,所述触摸面板配置为检测所述触摸面板的触摸面上的接触动作;以及微流控芯片,配置为根据检测到的所述接触动作对目标液滴执行预设操作。
- 根据权利要求1所述的微流控装置,还包括显示面板,其中,所述显示面板配置为显示所述目标液滴,所述触摸面板位于所述显示面板的显示侧,以及所述微流控芯片配置为根据所述接触动作对显示在所述显示面板上的所述目标液滴的操作,对所述目标液滴执行所述预设操作。
- 根据权利要求2所述的微流控装置,还包括图像采集装置,其中,所述图像采集装置配置为采集所述目标液滴的图像信息,并将所述目标液滴的图像信息传输至所述显示面板,以及所述显示面板配置为基于所述目标液滴的图像信息显示所述目标液滴。
- 根据权利要求1至3任一所述的微流控装置,还包括控制器,其中,所述控制器与所述触摸面板和所述微流控芯片信号连接,并配置为响应于所述触摸面板检测到的所述接触动作,控制所述微流控芯片对所述目标液滴执行所述预设操作。
- 根据权利要求4所述的微流控装置,其中,所述控制器还配置为根据所述接触动作来规划所述目标液滴的运动路线,并控制所述微流控芯片以驱动所述目标液滴按照所述运动路线进行移动。
- 根据权利要求4或5所述的微流控装置,其中,所述触摸面板、所述微流控芯片以及所述控制器中任意两者均可拆卸地连接。
- 根据权利要求1至6任一所述的微流控装置,其中,所述触摸面板的检测区与所述微流控芯片的操作区域相对应。
- 根据权利要求1至7任一项所述的微流控装置,其中,所述触摸面板和所述微流控芯片在垂直于所述触摸面板的所述触摸面的方向上重叠,且所述触摸面板的检测区至少是部分透明的,使得所述微流控芯片的操作区域可 见。
- 一种控制装置,包括:控制器、第一接口和第二接口,其中,所述第一接口配置为与触摸面板信号连接,所述第二接口配置为与微流控芯片信号连接,所述控制器配置为获取所述触摸面板对接触动作的检测结果,控制所述微流控芯片根据所述检测结果对目标液滴执行预设操作。
- 根据权利要求9所述的控制装置,其中,所述控制器包括:片上系统,配置为与所述第一接口信号连接并根据所述第一接口接收的来自所述触摸面板的触控信号确定出触控信息;以及微控制单元,配置为与所述第二接口信号连接,根据所述片上系统提供的所述触控信息生成驱动信号,并通过所述第二接口输出至所述微流控芯片。
- 一种用于微流控装置的操作方法,所述微流控装置包括触摸面板和微流控芯片,所述方法包括:通过所述触摸面板对所述触摸面板的触摸面上的接触动作进行检测;以及通过所述微流控芯片根据检测到的所述接触动作对目标液滴执行预设操作。
- 根据权利要求11所述的方法,其中,所述微流控装置还包括显示面板,所述显示面板配置为显示所述目标液滴,以及所述方法还包括:通过所述显示面板显示所述目标液滴。
- 根据权利要求12所述的方法,其中,所述通过所述微流控芯片根据检测到的所述接触动作对目标液滴执行预设操作的步骤,包括:通过所述微流控芯片根据所述接触动作对显示在所述显示面板上的所述目标液滴的操作,对所述目标液滴执行所述预设操作。
- 根据权利要求12或13所述的方法,其中,所述微流控装置还包括图像采集装置,以及所述通过所述显示面板显示所述目标液滴,包括:通过所述图像采集装置采集所述目标液滴的图像信息,并将将所述目标液滴的图像信息传输至所述显示面板;以及通过所述显示面板基于所述目标液滴的图像信息显示所述目标液滴。
- 根据权利要求11至14任一项所述的方法,其中,所述微流控装置还包括控制器,所述控制器与所述触摸面板和所述微流控芯片信号连接,以及所述通过所述微流控芯片根据检测到的所述接触动作对目标液滴执行所述预设操作,包括:响应于所述触摸面板检测到的所述接触动作,通过所述控制器控制所述微流控芯片以根据检测到的所述接触动作对目标液滴执行所述预设操作。
- 根据权利要求11至15任一项所述的方法,其中,所述预设操作包括以下中至少之一:移动、分离、聚合、施加电压、加热。
- 根据权利要求11至16任一项所述的方法,其中,所述接触动作包括点击动作,以及所述目标液滴为位于所述点击动作的发生位置在所述微流控芯片上的对应位置处的液滴。
- 根据权利要求11至16任一项所述的方法,其中,所述接触动作包括:从所述触摸面板上的第一位置处开始接触并持续到所述触摸面板上的第二位置的滑行动作,以及所述目标液滴为位于所述滑行动作的轨迹在所述微流控芯片上的对应轨迹上的液滴。
- 根据权利要求18所述的方法,其中,所述通过微流控芯片根据检测到的所述接触动作对目标液滴执行预设操作的步骤,包括:根据所述触摸面板检测到的所述滑行动作的轨迹来规划所述目标液滴的运动路线,并控制所述微流控芯片以驱动所述目标液滴按照所述运动路线进行移动。
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