WO2020197043A3 - Oral vaccine preparation for fish or crustaceans containing acid-treated low-molecular-weight alginic acid - Google Patents

Oral vaccine preparation for fish or crustaceans containing acid-treated low-molecular-weight alginic acid Download PDF

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Publication number
WO2020197043A3
WO2020197043A3 PCT/KR2019/017275 KR2019017275W WO2020197043A3 WO 2020197043 A3 WO2020197043 A3 WO 2020197043A3 KR 2019017275 W KR2019017275 W KR 2019017275W WO 2020197043 A3 WO2020197043 A3 WO 2020197043A3
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WO
WIPO (PCT)
Prior art keywords
fish
vaccine preparation
acid
molecular
oral vaccine
Prior art date
Application number
PCT/KR2019/017275
Other languages
French (fr)
Korean (ko)
Other versions
WO2020197043A2 (en
Inventor
안경진
이민경
김지연
김형미
정진송
Original Assignee
주식회사 준원지비아이
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 주식회사 준원지비아이 filed Critical 주식회사 준원지비아이
Publication of WO2020197043A2 publication Critical patent/WO2020197043A2/en
Publication of WO2020197043A3 publication Critical patent/WO2020197043A3/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/385Haptens or antigens, bound to carriers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/09Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/09Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092Streptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/107Vibrio
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/542Mucosal route oral/gastrointestinal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552Veterinary vaccine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6087Polysaccharides; Lipopolysaccharides [LPS]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Farming Of Fish And Shellfish (AREA)

Abstract

The present invention relates to an oral vaccine preparation for fish or crustaceans containing an acid-treated low-molecular-weight alginic acid. The oral vaccine preparation is prepared in the form of beads carrying an attenuated microorganism, and thus, simply through an oral administration method, can easily induce immunization against diseases caused by the corresponding microorganism. Accordingly, the preparation can also address existing problems with rising costs, reduction in the water quality of farms, and the like, which may occur due to spraying of large amounts of attenuated microorganisms or antibiotics, antimicrobial agents, and the like in fish farms.
PCT/KR2019/017275 2019-03-27 2019-12-09 Oral vaccine preparation for fish or crustaceans containing acid-treated low-molecular-weight alginic acid WO2020197043A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020190035030A KR102257242B1 (en) 2019-03-27 2019-03-27 Oral formulation of oral vaccine comprising low molecular weight alginate using acid treatment for fish or crustacea
KR10-2019-0035030 2019-03-27

Publications (2)

Publication Number Publication Date
WO2020197043A2 WO2020197043A2 (en) 2020-10-01
WO2020197043A3 true WO2020197043A3 (en) 2020-11-19

Family

ID=72611609

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2019/017275 WO2020197043A2 (en) 2019-03-27 2019-12-09 Oral vaccine preparation for fish or crustaceans containing acid-treated low-molecular-weight alginic acid

Country Status (2)

Country Link
KR (1) KR102257242B1 (en)
WO (1) WO2020197043A2 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20000032630A (en) * 1998-11-13 2000-06-15 박병권 Red tide eliminating composition and therapeutic composition for ectoparasitic diseases of fish using alginate polygalacturonite oligomer derivative

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101569151B1 (en) 2009-03-20 2015-11-16 (주)인터리스 A Vaccine Composition For cultured fish
KR20180105945A (en) 2017-03-16 2018-10-01 대한민국(농림축산식품부 농림축산검역본부장) Novel Salmonella Typhimurium strain and vaccine composition comprising the same
KR101953460B1 (en) 2017-03-21 2019-02-28 주식회사 코미팜 Method and apparatus for preparing inhibitable vaccine for prevention of stability bacterial disease including protected serum form of new streptococcus paraberis
KR20180112257A (en) 2017-04-03 2018-10-12 주식회사 이뮤너스 Pharmaceutical composition for preventing or treating edwardsiellosis of fish, and a method for preventing or treating edwardsiellosis of fish

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20000032630A (en) * 1998-11-13 2000-06-15 박병권 Red tide eliminating composition and therapeutic composition for ectoparasitic diseases of fish using alginate polygalacturonite oligomer derivative

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
EMBREGTS CARMEN W.E.; FORLENZA MARIA: "Oral vaccination of fish: Lessons from humans and veterinary species", DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY., PERGAMON PRESS., US, vol. 64, 25 March 2016 (2016-03-25), US, pages 118 - 137, XP029623504, ISSN: 0145-305X, DOI: 10.1016/j.dci.2016.03.024 *
F SAREI, N MOHAMMADPOUR DOUNIGHI, H ZOLFAGHARIAN, P KHAKI, S MORADI BIDHENDI: "Alginate nanoparticles as a promising adjuvant and vaccine delivery system", INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES, MEDKNOW PUBLICATIONS AND MEDIA PVT. LTD, INDIA, 1 July 2013 (2013-07-01), India, pages 442, XP055423455, DOI: 10.4103/0250-474X.119829 *
PHILIPPE E. RAMOS, ET AL.: "Effect of alginate molecular weight and M/G ratio in beads properties foreseeing the protection of probiotics", FOOD HYDROCOLLOIDS, ELSEVIER BV, NL, vol. 77, 1 April 2018 (2018-04-01), NL, pages 8 - 16, XP055622795, ISSN: 0268-005X, DOI: 10.1016/j.foodhyd.2017.08.031 *

Also Published As

Publication number Publication date
KR20200115829A (en) 2020-10-08
WO2020197043A2 (en) 2020-10-01
KR102257242B1 (en) 2021-05-28

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