WO2020169045A1 - Micro-delivery device - Google Patents
Micro-delivery device Download PDFInfo
- Publication number
- WO2020169045A1 WO2020169045A1 PCT/CN2020/075801 CN2020075801W WO2020169045A1 WO 2020169045 A1 WO2020169045 A1 WO 2020169045A1 CN 2020075801 W CN2020075801 W CN 2020075801W WO 2020169045 A1 WO2020169045 A1 WO 2020169045A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- planar electrode
- delivery device
- micro
- substrate
- sharp corner
- Prior art date
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14212—Pumping with an aspiration and an expulsion action
- A61M5/14224—Diaphragm type
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
- A61M5/14526—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons the piston being actuated by fluid pressure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/14586—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of a flexible diaphragm
- A61M5/14593—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of a flexible diaphragm the diaphragm being actuated by fluid pressure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D83/00—Containers or packages with special means for dispensing contents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D83/00—Containers or packages with special means for dispensing contents
- B65D83/0055—Containers or packages provided with a flexible bag or a deformable membrane or diaphragm for expelling the contents
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B19/00—Machines or pumps having pertinent characteristics not provided for in, or of interest apart from, groups F04B1/00 - F04B17/00
- F04B19/006—Micropumps
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B43/00—Machines, pumps, or pumping installations having flexible working members
- F04B43/02—Machines, pumps, or pumping installations having flexible working members having plate-like flexible members, e.g. diaphragms
- F04B43/04—Pumps having electric drive
- F04B43/043—Micropumps
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K99/00—Subject matter not provided for in other groups of this subclass
- F16K99/0001—Microvalves
- F16K99/0003—Constructional types of microvalves; Details of the cutting-off member
- F16K99/0015—Diaphragm or membrane valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M2005/14204—Pressure infusion, e.g. using pumps with gas-producing electrochemical cell
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/82—Internal energy supply devices
- A61M2205/8218—Gas operated
- A61M2205/8231—Gas operated using electrochemical gas generating device for the driving gas
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Vascular Medicine (AREA)
- Mechanical Engineering (AREA)
- General Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Fluid Mechanics (AREA)
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Water Treatment By Electricity Or Magnetism (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
Description
Claims (12)
- A micro-delivery device, comprising:a substrate having an upper surface;a shell disposed on the upper surface of the substrate and defining a chamber between the shell and the substrate;a planar electrode disposed on the upper surface of the substrate;a separator disposed in the chamber and dividing the chamber into an upper reservoir and a lower reservoir; anda cannula inserted in an opening of the rigid shell and in fluid communication with the upper reservoir;wherein at least one sharp corner is formed on the surface of the planar electrode.
- The micro-delivery device as claimed in claim 1, wherein the planar electrode has a first side surface and a second side surface which is opposite to the first side surface in a cross-sectional view, and at least one sharp corner is formed on the first side surface and/or the second side surface respectively.
- The micro-delivery device as claimed in claim 1, wherein the planar electrode has a first side surface and a second side surface which is opposite to the first side surface in a cross-sectional view, the planar electrode further has a top surface connecting the first side surface and the second side surface, and at least one sharp corner is formed on the top surface.
- The micro-delivery device as claimed in claim 1, wherein the planar electrode further comprises a top surface and a bottom surface opposite to the top surface, and an area of the top surface is larger than an area of the bottom surface, forming a sharp corner between the side surface and the top surface from a cross-section view.
- The micro-delivery device as claimed in claim 1, wherein the sharp corner has a sharp angle which has a range between 0.01-90°.
- The micro-delivery device as claimed in claim 1, wherein the sharp corner has a width which has a range between 0.01-100 μm.
- The micro-delivery device as claimed in claim 1, wherein the sharp corner is formed by the method of isotropic etching or anisotropic etching.
- The micro-delivery device as claimed in claim 1, 2, or 3, wherein the sharp corners are formed at and protruded from the surface in the shape of zig-zag.
- The micro-delivery device as claimed in claim 1, 2, or 3, wherein the sharp corners are formed at and protruded from the surface in the shape of tip of pyramid.
- The micro-delivery device as claimed in claim 1, wherein the planar electrode is a porous electrode.
- The micro-delivery device as claimed in claim 1, further comprising an electronic device is electrically connected to the planar electrode.
- The micro-delivery device as claimed in claim 1, wherein the planar electrode is hydrophilic and the substrate is hydrophilic.
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2020224897A AU2020224897A1 (en) | 2019-02-19 | 2020-02-19 | Micro-delivery device |
KR1020217029963A KR20210130761A (en) | 2019-02-19 | 2020-02-19 | smile delivery device |
CN202080015483.6A CN113543824A (en) | 2019-02-19 | 2020-02-19 | Micro delivery device |
JP2021548630A JP2022521228A (en) | 2019-02-19 | 2020-02-19 | Micro delivery device |
EP20759211.4A EP3927393A4 (en) | 2019-02-19 | 2020-02-19 | Micro-delivery device |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962807538P | 2019-02-19 | 2019-02-19 | |
US62/807,538 | 2019-02-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2020169045A1 true WO2020169045A1 (en) | 2020-08-27 |
Family
ID=72040599
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/CN2020/075801 WO2020169045A1 (en) | 2019-02-19 | 2020-02-19 | Micro-delivery device |
Country Status (8)
Country | Link |
---|---|
US (1) | US11460020B2 (en) |
EP (1) | EP3927393A4 (en) |
JP (1) | JP2022521228A (en) |
KR (1) | KR20210130761A (en) |
CN (1) | CN113543824A (en) |
AU (1) | AU2020224897A1 (en) |
TW (1) | TW202039014A (en) |
WO (1) | WO2020169045A1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114517775A (en) * | 2020-11-18 | 2022-05-20 | 洁霺生医科技股份有限公司 | Electrochemical pump device with grid-assembled electrodes |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI741949B (en) * | 2020-02-21 | 2021-10-01 | 潔霺生醫科技股份有限公司 | Electrochemical pump and delivery device |
TWI785565B (en) * | 2021-04-15 | 2022-12-01 | 國立高雄科技大學 | Device and method for electrolysis pump for drug delivery |
Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4297689A (en) * | 1980-01-08 | 1981-10-27 | Interscan Corporation | Personnel-carried dosimeter |
US20050252772A1 (en) * | 2002-07-17 | 2005-11-17 | Paul Philip H | Flow device |
US20070125650A1 (en) * | 2005-09-14 | 2007-06-07 | Stmicroeletronics S.R.L. | Treatment of Biological Samples Using Dielectrophoresis |
CN101356675A (en) * | 2006-06-26 | 2009-01-28 | 松下电器产业株式会社 | Solid polymer electrolyte fuel cell |
US20100320088A1 (en) * | 2006-12-05 | 2010-12-23 | Commissariat A L'energie | Microdevice for treating liquid specimens |
CN102202708A (en) * | 2008-05-08 | 2011-09-28 | 迷你泵有限责任公司 | Drug-delivery pumps and methods of manufacture |
CN103108665A (en) * | 2010-04-20 | 2013-05-15 | 迷你泵有限责任公司 | Electrolytically driven drug pump devices |
US20160206811A1 (en) * | 2014-12-30 | 2016-07-21 | Jason Shih | Implantable Electrolytic Diaphragm Pumps |
US20180104408A1 (en) * | 2016-10-17 | 2018-04-19 | MicroMED Co., Ltd. | Micro delivery device |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1910810B (en) * | 2004-02-05 | 2010-04-21 | 松下电器产业株式会社 | Actuator and method for manufacturing planar electrode support for actuator |
IL169807A (en) * | 2005-07-21 | 2015-03-31 | Steadymed Ltd | Drug delivery device |
TWI261868B (en) * | 2005-09-06 | 2006-09-11 | Wintek Corp | Electrode partition wall |
US9333297B2 (en) * | 2008-05-08 | 2016-05-10 | Minipumps, Llc | Drug-delivery pump with intelligent control |
TW201120516A (en) * | 2009-12-03 | 2011-06-16 | Chunghwa Picture Tubes Ltd | Multistable liquid crystal display device and the driving method thereof |
US20130184640A1 (en) * | 2010-04-20 | 2013-07-18 | Minipumps, Llc | Accurate flow control in drug pump devices |
EP2689142B1 (en) | 2011-03-21 | 2017-05-03 | Danfoss A/S | Valve |
US8939930B2 (en) * | 2011-11-18 | 2015-01-27 | Minipumps, Llc | Accurate flow control in drug pump devices |
US20140088554A1 (en) * | 2012-09-24 | 2014-03-27 | Po-Ying Li | Drug-delivery pump with intelligent control |
WO2014204957A1 (en) * | 2013-06-17 | 2014-12-24 | Replenish, Inc. | Vented implantable drug-delivery device |
CA2915985A1 (en) * | 2013-06-25 | 2014-12-31 | Andrew Dunn | Electrolysis recombination control mask and method of manufacture thereof |
FR3068625B1 (en) * | 2017-07-06 | 2019-08-09 | Aptar France Sas | DEVICE FOR DISPENSING FLUID PRODUCT. |
-
2020
- 2020-02-18 US US16/793,143 patent/US11460020B2/en active Active
- 2020-02-19 KR KR1020217029963A patent/KR20210130761A/en unknown
- 2020-02-19 JP JP2021548630A patent/JP2022521228A/en active Pending
- 2020-02-19 CN CN202080015483.6A patent/CN113543824A/en active Pending
- 2020-02-19 EP EP20759211.4A patent/EP3927393A4/en active Pending
- 2020-02-19 WO PCT/CN2020/075801 patent/WO2020169045A1/en unknown
- 2020-02-19 AU AU2020224897A patent/AU2020224897A1/en active Pending
- 2020-02-19 TW TW109105349A patent/TW202039014A/en unknown
Patent Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
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US4297689A (en) * | 1980-01-08 | 1981-10-27 | Interscan Corporation | Personnel-carried dosimeter |
US20050252772A1 (en) * | 2002-07-17 | 2005-11-17 | Paul Philip H | Flow device |
US20070125650A1 (en) * | 2005-09-14 | 2007-06-07 | Stmicroeletronics S.R.L. | Treatment of Biological Samples Using Dielectrophoresis |
CN101356675A (en) * | 2006-06-26 | 2009-01-28 | 松下电器产业株式会社 | Solid polymer electrolyte fuel cell |
US20100320088A1 (en) * | 2006-12-05 | 2010-12-23 | Commissariat A L'energie | Microdevice for treating liquid specimens |
CN102202708A (en) * | 2008-05-08 | 2011-09-28 | 迷你泵有限责任公司 | Drug-delivery pumps and methods of manufacture |
CN103108665A (en) * | 2010-04-20 | 2013-05-15 | 迷你泵有限责任公司 | Electrolytically driven drug pump devices |
US20160206811A1 (en) * | 2014-12-30 | 2016-07-21 | Jason Shih | Implantable Electrolytic Diaphragm Pumps |
US20180104408A1 (en) * | 2016-10-17 | 2018-04-19 | MicroMED Co., Ltd. | Micro delivery device |
Non-Patent Citations (1)
Title |
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See also references of EP3927393A4 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114517775A (en) * | 2020-11-18 | 2022-05-20 | 洁霺生医科技股份有限公司 | Electrochemical pump device with grid-assembled electrodes |
WO2022105576A1 (en) * | 2020-11-18 | 2022-05-27 | 洁霺生医科技股份有限公司 | Electrochemical pump device of grid combined electrode |
Also Published As
Publication number | Publication date |
---|---|
JP2022521228A (en) | 2022-04-06 |
TW202039014A (en) | 2020-11-01 |
KR20210130761A (en) | 2021-11-01 |
EP3927393A4 (en) | 2022-11-02 |
CN113543824A (en) | 2021-10-22 |
AU2020224897A1 (en) | 2021-09-16 |
US11460020B2 (en) | 2022-10-04 |
US20200263679A1 (en) | 2020-08-20 |
EP3927393A1 (en) | 2021-12-29 |
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