WO2020155236A1

WO2020155236A1 - Monitoring host and cardiopulmonary bypass system

Info

Publication number: WO2020155236A1
Application number: PCT/CN2019/075950
Authority: WO
Inventors: 王维宁; 李晓坤; 刘日东
Original assignee: 江苏赛腾医疗科技有限公司
Priority date: 2019-01-31
Filing date: 2019-02-22
Publication date: 2020-08-06
Also published as: CN109771724A

Abstract

Provided are a monitoring host (10) and a cardiopulmonary bypass system (1), the monitoring host (10) comprises a control module (101), a power supply module (102) and a sensing module (103), the power supply module (102) and the sensing module (103) are electrically connected with the control module (101) respectively, the power supply module (102) supplies power to the control module (101) and the sensing module (103); the sensing module (103) monitors the blood state and generates a sensing signal, and transmits the sensing signal to the control module (101), the control module (101) processes the sensing signal and acquires state data of the blood according to the sensing signal, the power supply module (102) comprises at least one of a direct current interface(1022) and a battery (1023). The power supply module (102) of the monitoring host (10) of the cardiopulmonary bypass system (1) utilizes a vehicle-mounted direct current power supply and a direct current power supply of a built-in battery, and the cardiopulmonary bypass system (1) can be used under the condition of no stabilized power supplies, and prolong the using time under the condition of no stabilized power supplies.

Description

Monitoring host and cardiopulmonary bypass system

Technical field

The invention relates to the field of medical devices used for extracorporeal life support, and in particular to a monitoring host and a cardiopulmonary bypass system.

Background technique

Cardiopulmonary bypass system, also known as extracorporeal membrane oxygenation (ECMO), is a mechanical circulatory assist technology that can be inserted percutaneously. The cardiopulmonary bypass system usually consists of three parts: the main engine, the pump head and the membrane oxygenator. The host computer controls and monitors the operation of the cardiopulmonary bypass system. The pump head is used to circulate the blood inside and outside the body, and the membrane oxygenator is used to provide oxygen and exchange carbon dioxide in the blood discharged from the body. The cardiopulmonary bypass system mainly drains the venous blood in the patient's body to the outside of the body, and the blood that passes through the membrane oxygenator to oxygenate and remove the carbon dioxide in the blood is returned to the patient's body. According to the different ways of blood reinfusion, the cardiopulmonary bypass system mainly has two forms: venous-to-venous ECMO (VV-ECMO) and venous-arterial ECMO (VA-ECMO). The former only has a respiratory assist function. The latter has both circulation and breathing assistance.

Since the cardiopulmonary bypass system is usually used for emergency patients and patient transfer between hospitals, but the weight of the host of the cardiopulmonary bypass system is greater than 10 kg, the power supply in the host can be used without connecting to the mains, but its independent working time is short, resulting in cardiopulmonary The portability of the diversion system is poor. Of course, you can choose not to use the host, and directly supply power to the pump head through the battery. The pump head directly drives the membrane oxygenator to operate. However, in this mode, the flow of blood and bubbles discharged from the body cannot be detected because there is no host. , It brings security risks.

Summary of the invention

The embodiment of the present invention provides a monitoring host and a cardiopulmonary bypass system to solve the problem that the cardiopulmonary bypass system can not be used for a long time without a stable power supply.

In order to solve the above technical problems, the present invention is implemented as follows:

In a first aspect, a monitoring host is provided, which includes a control module, a power supply module, and a sensing module. The power supply module and the sensing module are respectively electrically connected to the control module, and the power supply module supplies power to the control module and The sensing module, the sensing module monitors the state of the blood, generates a sensing signal, and transmits the sensing signal to the control module, the control module processes the sensing signal, and obtains the blood according to the sensing signal The power module includes at least one of a direct current interface and a battery.

In a second aspect, a cardiopulmonary bypass system is provided, including the monitoring host, a pump, and a membrane oxygenator as described above, the monitoring host is electrically connected to the pump, and the pump is connected to the membrane oxygenator through a pipeline, The pump and the membrane oxygenator are respectively connected to blood vessels in the body through a medical cannula. When the blood of the blood vessels in the body circulates through the pump and the membrane oxygenator, the monitoring host monitors the state of the blood.

In the embodiment of the present invention, the power module of the monitoring host of the cardiopulmonary bypass system of the present invention uses the on-board DC power supply and the DC power supply of the built-in battery, so that the cardiopulmonary bypass system of the present invention can be used without a stable power supply. And can extend the use time in the state without stable power supply.

Description of the drawings

The drawings described here are used to provide a further understanding of the present invention and constitute a part of the present invention. The exemplary embodiments and descriptions of the present invention are used to explain the present invention, and do not constitute an improper limitation of the present invention. In the attached picture:

Figure 1 is a block diagram of a cardiopulmonary bypass system according to a first embodiment of the present invention;

2 is a block diagram of the monitoring host in the first embodiment of the present invention;

Fig. 3 is another block diagram of the monitoring host in the first embodiment of the present invention.

detailed description

The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are part of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative work shall fall within the protection scope of the present invention.

Please refer to FIG. 1, which is a block diagram of a cardiopulmonary bypass system according to a first embodiment of the present invention; as shown in the figure, this embodiment provides a cardiopulmonary bypass system 1, which includes a monitoring host 10 and a pump 12. And membrane oxygenator 13. The monitoring host 10 is connected to a pump 12, and the pump 12 is connected to a membrane oxygenator 13. During the operation of the cardiopulmonary bypass system 1 of this embodiment, two medical cannulas are first inserted into the blood vessels of the heart or lungs in the human body. One of the two medical cannulas is used as the blood output end, and the other is used as the blood output port. Blood input port. The pump 12 is connected to a medical cannula as a blood output end, and the medical cannula as a blood output end is usually inserted into a venous blood vessel. The membrane oxygenator 13 is connected to a medical cannula as a liquid input end, and the medical cannula as a liquid input end is usually inserted into a venous blood vessel or an arterial blood vessel. The pump 12 and the membrane oxygenator 13 are connected by pipelines. The monitoring host 10 drives the pump 12 to operate. The medical cannula used as the blood output port outputs venous blood in the body. The venous blood in the body flows through the pump 12 and flows into the membrane oxygenator 13, which oxygenates and discharges the venous blood in the body Carbon dioxide in the blood in the veins of the body. The membrane oxygenator 13 outputs oxygenated blood, and the oxygenated blood is fed into a venous or arterial blood vessel from a medical cannula as a blood input end, so that the human heart or lungs, the pump 12 and the membrane oxygenator 13 form Circulation, when the pump 12 continues to operate, the venous blood in the heart or lungs is discharged, and then the venous blood is oxygenated by the membrane oxygenator 13, and finally the oxygenated blood is infused to the heart or lungs. The monitoring host 10 monitors the state of the blood during the blood circulation process, such as blood flow, bubble volume, temperature, pressure, or blood oxygen saturation.

Please refer to FIGS. 2 and 3 together, which are block diagrams of the monitoring host according to the first embodiment of the present invention; as shown in the figure, the monitoring host 10 includes a control module 101, a power module 102, and a sensing module 103. The power module 102 and the sensor module 103 are electrically connected to the control module 101 respectively. The control module 101 includes a first processor 1011, a power conversion circuit 1012, and a sensing signal conversion circuit 1013. The power conversion circuit 1012 and the sensing signal generation circuit 1013 are electrically connected to the first processor 1011, and the power conversion circuit 1012 is electrically connected. The power module 102 is used to adjust the voltage or current form of the power signal input by the power module 102, and the adjusted power signal is supplied to the first processor 1011. The power conversion circuit 1012 includes at least one of a rectifier circuit 10121 and a transformer circuit 10122, which mainly depends on the source of the power signal supplied by the power module 102. The power signal provided by the power module 102 includes the AC power signal of the mains, At least one of the DC power signal of the vehicle and the DC power signal of the battery. If there are multiple sources of the power signal provided by the power module 102, the power conversion circuit 1012 further includes a power selection circuit 10123, which is electrically connected The power output terminal of at least one of the rectifier circuit 10121 and the transformer circuit 10122 is used to switch the source of the power signal.

For specific applications, the power module 102 can provide the above three types of power sources, which include an AC power interface 1021, a DC power interface 1022, and a battery 1023. The AC power interface 1021 is used to connect to external mains, and the DC power interface 1022 is used to connect to vehicle power supplies or other external DC power sources. . The power conversion circuit 1012 electrically connected to the power module 102 of this embodiment includes a rectifier circuit 10121, two transformer circuits 10122, and a power selection circuit 10123. The power input end of the rectifier circuit 10121 is electrically connected to the AC interface 1021 and the rectifier circuit 10121 The power output terminal of is electrically connected to the power selection circuit 10123. The power input terminals of the two transformer circuits 10122 are respectively electrically connected to the DC interface 1022 and the battery 1023, and the power output terminals of the two transformer circuits 10122 are respectively electrically connected to the power selection circuit 10123. The power selection circuit 10123 is electrically connected to the first processor 1011, and the power selection circuit 10123 is implemented using a power switch.

When the power module 102 provides an AC power signal, the power selection circuit 10123 makes the AC power interface 1021, the rectifier circuit 10121 and the first processor 1011 form a path. At this time, the AC power interface 1021 is connected to the external mains, the AC power signal of the mains enters the rectifier circuit 10121 through the AC power interface 1021, and the rectifier circuit 10121 converts the AC power signal into a DC power signal suitable for the first processor 1011. The DC power signal passes The power selection circuit 10123 is transmitted to the first processor 1011, so that the first processor 1011 starts to operate.

When the power module 102 provides a DC power signal, the power selection circuit 10123 makes the DC power interface 1022, the transformer circuit 10122 electrically connected to the DC power interface 1022 and the first processor 1011 form a path, wherein the DC power interface 1022 is connected to an external vehicle power supply; Or the power supply selection circuit 10123 allows the battery 1023, the transformer circuit 10122 electrically connected to the battery 1023, and the first processor 1011 to form a path. The vehicle power supply enters the transformer circuit 10122 through the DC power signal provided by the DC power interface 1021 or the battery 1023, and the transformer circuit 10122 adjusts the voltage of the DC power signal to a voltage suitable for the DC power signal used by the first processor 1011. The adjusted DC The power signal is transmitted to the first processor 1011 through the power selection circuit 10123, so that the first processor 1011 starts to operate. The power output end of the power selection circuit 10123 also provides DC power to other modules in the monitoring host 10 so that other modules can operate normally.

The sensor signal conversion circuit 1013 is electrically connected to the sensor module 103 for receiving the sensor signal transmitted by the sensor module 103; it can also convert the format of the sensor signal so that the format of the converted sensor signal conforms to the first processing The processing format of the processor 1011; it can further process the converted sensor signal and transmit the processed sensor signal to the first processor 1011. The sensor signal conversion circuit 1013 includes at least one of an analog-digital conversion circuit 10131 and a data conversion interface 10132, which is mainly determined according to the format of the sensor signal generated by the sensor module 103. If the sensor signal generated by the sensor module 103 When the signal is a digital signal, the sensor signal needs to be converted by the analog-digital conversion circuit 10131. If the sensing signal generated by the sensing module 103 is an analog signal, the sensing signal can be transmitted through the data conversion interface 10132. The sensing signal conversion circuit 1013 further includes a second processor 10133, which is electrically connected to at least one of the analog-digital conversion circuit 10131 and the data conversion interface 10132 for preprocessing the sensing signal or the converted sensing signal. signal. The second processor 10133 is electrically connected to the first processor 1011 and transmits the preprocessed sensor signal to the first processor 1011. The second processor 10133 preprocessing the sensing signal can reduce the calculation of the first processor 1011, thereby improving the efficiency of the first processor 1011. The sensor in the sensing module 103 can be selected from at least one of the flow sensor 1030, the temperature sensor 1031, the pressure sensor 1032, and the blood oxygen saturation sensor 1033. The main sensor (for example: the flow sensor 1030) can be added, and the auxiliary sensor can be reduced. (For example: temperature sensor 1031, pressure sensor 1032, blood oxygen saturation sensor 1033).

For specific applications, the sensing module 103 includes a flow sensor 1030, a temperature sensor 1031, a pressure sensor 1032, and a blood oxygen saturation sensor 1033. The sensing signals generated by the temperature sensor 1031 and the pressure sensor 1032 are digital signals, and the flow sensor 1030 and blood oxygen The sensing signal generated by the saturation sensor 1033 is an analog signal. The sensing signal conversion circuit 1013 electrically connected to the sensing module 103 of this embodiment includes two analog-digital conversion circuits 10131, two data conversion interfaces 10132, and a second processor 10133. The two analog-digital conversion circuits 10131 are electrically connected to each other. The temperature sensor 1031 and the pressure sensor 1032 are connected, the two data conversion interfaces 10132 are electrically connected to the flow sensor 1031 and the blood oxygen saturation sensor 1033 respectively, and the second processor 10133 is electrically connected to the first processor 1011. The flow sensor 1030, the temperature sensor 1031, the pressure sensor 1032 and the blood oxygen saturation sensor 1033 respectively detect the flow, temperature, pressure and blood oxygen saturation of the blood output from the patient's body, and generate flow sensor signals and temperature sensor signals , Pressure sensor signal and blood oxygen saturation sensor signal, temperature sensor signal and pressure sensor signal are analog signals, which are converted into digital by analog-digital conversion circuit 10131 electrically connected to temperature sensor 1031 and pressure sensor 1032, respectively The signals, the converted temperature sensing signals and pressure sensing signals are sent to the second processor 10133. The flow sensing signal and the blood oxygen saturation sensing signal are analog signals, and the flow sensing signal and the blood oxygen saturation sensing signal are directly transmitted to the second processor 10133 through the data conversion interface 10132, respectively. The second processor 10133 preprocesses the converted flow sensor signal, temperature sensor signal, pressure sensor signal and blood oxygen saturation sensor signal, and transmits the preprocessed flow sensor signal, temperature sensor signal, and pressure The sensing signal and the blood oxygen saturation sensing signal are sent to the first processor 1011.

Furthermore, the monitoring host 10 further includes a display module 104, an input module 105, and a storage module 106. The display module 104, the input module 105, and the storage module 106 are respectively electrically connected to the first processor 1011, and the first processor 1011 processes After sensing the signal, the blood status data is obtained, and the display signal is generated at the same time, and the display signal is transmitted to the display module 104. The display module 104 displays the blood status data according to the display signal to facilitate the user to monitor the patient's physical status. The input module 105 can be a button or a knob. The monitoring parameter can be adjusted or set in the first processor 1011 through the input of the input module 105. The monitoring parameter can be the monitoring threshold of the blood state data. The first processor 1011 judges according to the monitoring parameter Whether the blood status data exceeds the monitoring threshold value, if the blood status data exceeds the monitoring threshold value, the first processor 1011 sends a warning signal to the display module 104, and the display module 104 displays the warning information according to the warning signal. The storage module 106 stores blood status data. The storage module 106 can be an internal memory or an external memory. The internal memory includes flash memory, read-only memory or random access memory, and the external memory includes a floppy disk, a hard disk, or a solid state disk.

When the cardiopulmonary bypass system 1 of this embodiment is in use, the power supply provided by the power module 102 of the monitoring host 10 can be an external AC power supply, an external DC power supply, or a battery 1023. The power supply module 102 of this embodiment uses an external DC power supply. The external DC power supply is electrically connected to the DC interface 1022 in the power supply module 102 that is electrically connected to the transformer circuit 10122. The DC power signal is adjusted by the transformer circuit 10122 to adjust its voltage. The adjusted DC power signal is transmitted to the monitoring host 10, the portable first processor 1011, the flow sensor 1030 of the sensing module 103, the temperature sensor 1031, the pressure sensor 1032, the blood oxygen saturation sensor 1033, the second processor 10133 and the display The module 104 enables the modules of the monitoring host 10 to operate normally.

There is no motor module in the monitoring host 10 to avoid the weight increase of the monitoring host 10, so the monitoring host 10 needs to be used with a pump 12 with a built-in motor module. The first processor 1011 first generates a motor control signal, and transmits the motor control signal to the pump 12, and the pump 12 starts to operate according to the motor control signal. After the pump 12 starts to operate, the venous blood in the fluid is oxygenated through the membrane oxygenator 13, and the membrane oxygenator 13 inputs the oxygenated blood to the venous or arterial blood vessels in the patient. In the process of blood circulation, the flow sensor 1030, temperature sensor 1031, pressure sensor 1032 and blood oxygen saturation sensor 1033 of the sensing module 103 respectively detect the flow, temperature, pressure and blood oxygen saturation of the blood, and respectively generate flow Sensing signal, temperature sensing signal, pressure sensing signal and blood oxygen saturation sensing signal, and transmitting flow sensing signal, temperature sensing signal, pressure sensing signal and blood oxygen saturation sensing signal to the second processing The second processor 10133 preprocesses the flow sensor signal, temperature sensor signal, pressure sensor signal and blood oxygen saturation sensor signal. The second processor 10133 transmits the preprocessed flow sensor signal, temperature sensor Signal, pressure sensing signal, and blood oxygen saturation sensing signal to the first processor 1011, and the first processor 1011 transmits the preprocessed flow sensing signal, temperature sensing signal, pressure sensing signal, and blood oxygen saturation The sensory signal knows the current blood flow, temperature, pressure and blood oxygen saturation and other blood state data. The user can set the monitoring threshold values of flow, temperature, pressure and blood oxygen saturation in the first processor 1011 through the input module 105, and the portable processor 111 can judge the blood flow, temperature, pressure and blood oxygen saturation. Whether at least one of them exceeds the corresponding monitoring threshold, if it is determined that at least one of blood flow, temperature, pressure, and blood oxygen saturation exceeds the monitoring threshold, the first processor 1011 generates a warning signal and sends the warning signal to the display Module 104, the display module 104 displays warning information according to the warning signal, and the user can take other medical measures through the warning information.

To sum up, the present invention provides a monitoring host and a cardiopulmonary bypass system. The power module of the monitoring host can use AC power from mains, DC power on the vehicle, and DC power with built-in battery. The monitoring host can be used without a stable power supply. When there is no stable power supply, the vehicle's DC power supply and the built-in battery DC power supply can be used interchangeably to extend the working time of the monitoring host without a stable power supply.

It should be noted that, in this article, the terms "including", "including" or any other variations thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements not only includes those elements, It also includes other elements not explicitly listed, or elements inherent to the process, method, article, or device. If there are no more restrictions, the element defined by the sentence "including a..." does not exclude the existence of other identical elements in the process, method, article or device that includes the element.

The embodiments of the present invention are described above with reference to the accompanying drawings, but the present invention is not limited to the above-mentioned specific embodiments. The above-mentioned specific embodiments are only illustrative and not restrictive. Those of ordinary skill in the art are Under the enlightenment of the present invention, many forms can be made without departing from the purpose of the present invention and the scope of protection of the claims, and they all fall within the protection of the present invention.

Claims

A monitoring host, characterized in that it includes a control module, a power supply module, and a sensing module. The power supply module and the sensing module are respectively electrically connected to the control module. The power supply module supplies power to the control module. Module and the sensing module, the sensing module monitors the state of the blood, generates a sensing signal, and transmits the sensing signal to the control module, and the control module processes the sensing signal, The blood status data is obtained according to the sensing signal, and the power module includes at least one of a direct current interface and a battery.
The monitoring host according to claim 1, wherein the control module includes a first processor, a power conversion circuit, and a sensing signal conversion circuit, and the power conversion circuit and the sensing signal conversion circuit are electrically respectively The first processor is connected, the power module is electrically connected to the power conversion circuit, and the sensing module is electrically connected to the sensing signal conversion circuit.
The monitoring host according to claim 1, wherein the power supply module further comprises an AC power interface.
The monitoring host according to claim 3, wherein the power module is the AC power interface, the power conversion circuit includes a rectifier circuit, and the rectifier circuit is electrically connected to the AC power interface and the first processor. Device.
The monitoring host according to claim 3, wherein the power module is the direct current interface or the battery, the power conversion circuit includes a transformer circuit, and the direct current interface or the battery is electrically connected to the The voltage transformation circuit is electrically connected to the first processor.
The monitoring host according to claim 3, wherein the power module includes the AC power interface, the DC power interface and the battery, the power conversion circuit includes a rectifier circuit and two transformer circuits, the The AC power interface is electrically connected to the rectifier circuit, the DC power interface and the battery are respectively electrically connected to the corresponding transformer circuit, and the rectifier circuit and the two transformer circuits are respectively connected to the first The processor is electrically connected.
8. The monitoring host according to claim 6, wherein the power conversion circuit further comprises a power selection circuit, and the power selection circuit is electrically connected to the first processor and the rectifier circuit and the two Between transformer circuits.
The monitoring host according to claim 1, wherein the sensor module includes at least one of a flow sensor, a temperature sensor, a pressure sensor, and a blood oxygen saturation sensor.
The monitoring host according to claim 8, wherein the sensing module includes at least one of the flow sensor and the blood oxygen saturation sensor, and the sensing signal conversion circuit includes at least one data conversion interface At least one of the flow sensor and the blood oxygen saturation sensor is electrically connected to the corresponding data conversion interface, and the data conversion interface is electrically connected to the first processor.
The monitoring host according to claim 9, wherein the sensor signal conversion circuit further comprises a second processor, and the second processor is electrically connected to the first processor and the data conversion interface. between.
The monitoring host according to claim 8, wherein the sensing module includes at least one of the temperature sensor and the pressure sensor, and the sensing signal conversion circuit includes at least one analog-to-digital conversion circuit, so At least one of the temperature sensor and the pressure sensor is electrically connected to the corresponding analog-digital conversion circuit, and the analog-digital conversion circuit is electrically connected to the first processor.
The monitoring host according to claim 11, wherein the sensor signal conversion circuit further comprises a second processor, and the second processor is electrically connected to the first processor and the analog-digital conversion circuit between.
The monitoring host according to claim 1, wherein the monitoring host further comprises a display module, the display module is electrically connected to the control module, and the control module generates a display signal according to the sensing signal, and The display signal is transmitted to the display module, and the display module displays the state data of the blood according to the display signal.
The heart monitoring host according to claim 1, wherein the monitoring host further comprises an input module, the input module is electrically connected to the control module, and the control module is set or adjusted through the input module Monitoring parameters.
The monitoring host according to claim 1, wherein the monitoring host further comprises a storage module, and the storage module stores status data of the blood.
A cardiopulmonary bypass system, comprising the monitoring host, a pump, and a membrane oxygenator according to any one of claims 1-15, the monitoring host is electrically connected to the pump, and the pump The membrane oxygenator is connected through a pipeline, the pump and the membrane oxygenator are respectively connected to blood vessels in the body through a medical cannula, when the blood in the blood vessels in the body passes through the pump and the membrane oxygenator When circulating, the monitoring host monitors the state of the blood.